Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_009_L15
(866 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P51990|RO22_XENLA Heterogeneous nuclear ribonucleoprotei... 97 4e-20
sp|P51989|RO21_XENLA Heterogeneous nuclear ribonucleoprotei... 97 6e-20
sp|P22626|ROA2_HUMAN Heterogeneous nuclear ribonucleoprotei... 95 2e-19
sp|O88569|ROA2_MOUSE Heterogeneous nuclear ribonucleoprotei... 95 2e-19
sp|Q22037|ROA1_CAEEL Heterogeneous nuclear ribonucleoprotei... 87 6e-17
sp|P48810|RB87F_DROME Heterogeneous nuclear ribonucleoprote... 85 2e-16
sp|P49312|ROA1_MOUSE Heterogeneous nuclear ribonucleoprotei... 85 3e-16
sp|P09651|ROA1_HUMAN Heterogeneous nuclear ribonucleoprotei... 85 3e-16
sp|P17130|ROA1_XENLA Heterogeneous nuclear ribonucleoprotei... 84 4e-16
sp|P09867|ROA1_BOVIN Heterogeneous nuclear ribonucleoprotei... 84 5e-16
>sp|P51990|RO22_XENLA Heterogeneous nuclear ribonucleoprotein A2 homolog 2 (hnRNP A2(B))
Length = 358
Score = 97.4 bits (241), Expect = 4e-20
Identities = 44/85 (51%), Positives = 58/85 (68%)
Frame = +1
Query: 13 GLKKDVTTEHLRHYFGSYGTITDCEIVTWKDSGESRGFGFVTFDDYDPVDKAILYKPHQI 192
G+K+D HLR YF YG I EI+T K SG+ RGFGFVTF+D+DPVDK +L K H I
Sbjct: 106 GIKEDTEEHHLREYFEEYGKIESTEIITDKQSGKKRGFGFVTFNDHDPVDKIVLQKYHTI 165
Query: 193 GSSRVDVKKALSKDEMEEIRRKQQN 267
+V+KALSK EM++++ + N
Sbjct: 166 NGHNAEVRKALSKQEMQDVQNTRNN 190
Score = 62.8 bits (151), Expect = 1e-09
Identities = 30/75 (40%), Positives = 47/75 (62%)
Frame = +1
Query: 13 GLKKDVTTEHLRHYFGSYGTITDCEIVTWKDSGESRGFGFVTFDDYDPVDKAILYKPHQI 192
GL + T E LR+++ +G +TDC ++ S SRGFGFVTF + VD A+ +PH I
Sbjct: 15 GLSFETTEESLRNFYEQWGQLTDCVVMRDPASKRSRGFGFVTFSCMNEVDAAMSARPHTI 74
Query: 193 GSSRVDVKKALSKDE 237
V+ K+A++++E
Sbjct: 75 DGRVVEPKRAVAREE 89
>sp|P51989|RO21_XENLA Heterogeneous nuclear ribonucleoprotein A2 homolog 1 (hnRNP A2(A))
Length = 346
Score = 97.1 bits (240), Expect = 6e-20
Identities = 44/85 (51%), Positives = 57/85 (67%)
Frame = +1
Query: 13 GLKKDVTTEHLRHYFGSYGTITDCEIVTWKDSGESRGFGFVTFDDYDPVDKAILYKPHQI 192
G+K+D HLR YF YG I EI+T K SG+ RGF FVTFDD+DPVDK +L K H I
Sbjct: 106 GIKEDTEEHHLREYFEEYGKIDSIEIITDKQSGKKRGFAFVTFDDHDPVDKIVLQKYHTI 165
Query: 193 GSSRVDVKKALSKDEMEEIRRKQQN 267
+V+KALSK EM++++ + N
Sbjct: 166 NGHNAEVRKALSKQEMQDVQNTRNN 190
Score = 67.0 bits (162), Expect = 6e-11
Identities = 32/75 (42%), Positives = 48/75 (64%)
Frame = +1
Query: 13 GLKKDVTTEHLRHYFGSYGTITDCEIVTWKDSGESRGFGFVTFDDYDPVDKAILYKPHQI 192
GL + T E LR+Y+ +GT+TDC ++ S SRGFGFVTF + VD A+ +PH I
Sbjct: 15 GLSFETTEESLRNYYEQWGTLTDCVVMRDPASKRSRGFGFVTFSCMNEVDAAMATRPHTI 74
Query: 193 GSSRVDVKKALSKDE 237
V+ K+A++++E
Sbjct: 75 DGRVVEPKRAVAREE 89
>sp|P22626|ROA2_HUMAN Heterogeneous nuclear ribonucleoproteins A2/B1 (hnRNP A2 / hnRNP
B1)
Length = 353
Score = 95.1 bits (235), Expect = 2e-19
Identities = 43/80 (53%), Positives = 56/80 (70%)
Frame = +1
Query: 13 GLKKDVTTEHLRHYFGSYGTITDCEIVTWKDSGESRGFGFVTFDDYDPVDKAILYKPHQI 192
G+K+D HLR YF YG I EI+T + SG+ RGFGFVTFDD+DPVDK +L K H I
Sbjct: 118 GIKEDTEEHHLRDYFEEYGKIDTIEIITDRQSGKKRGFGFVTFDDHDPVDKIVLQKYHTI 177
Query: 193 GSSRVDVKKALSKDEMEEIR 252
+V+KALS+ EM+E++
Sbjct: 178 NGHNAEVRKALSRQEMQEVQ 197
Score = 65.1 bits (157), Expect = 2e-10
Identities = 31/75 (41%), Positives = 46/75 (61%)
Frame = +1
Query: 13 GLKKDVTTEHLRHYFGSYGTITDCEIVTWKDSGESRGFGFVTFDDYDPVDKAILYKPHQI 192
GL + T E LR+Y+ +G +TDC ++ S SRGFGFVTF VD A+ +PH I
Sbjct: 27 GLSFETTEESLRNYYEQWGKLTDCVVMRDPASKRSRGFGFVTFSSMAEVDAAMAARPHSI 86
Query: 193 GSSRVDVKKALSKDE 237
V+ K+A++++E
Sbjct: 87 DGRVVEPKRAVAREE 101
>sp|O88569|ROA2_MOUSE Heterogeneous nuclear ribonucleoproteins A2/B1 (hnRNP A2 / hnRNP
B1)
Length = 341
Score = 95.1 bits (235), Expect = 2e-19
Identities = 43/80 (53%), Positives = 56/80 (70%)
Frame = +1
Query: 13 GLKKDVTTEHLRHYFGSYGTITDCEIVTWKDSGESRGFGFVTFDDYDPVDKAILYKPHQI 192
G+K+D HLR YF YG I EI+T + SG+ RGFGFVTFDD+DPVDK +L K H I
Sbjct: 106 GIKEDTEEHHLRDYFEEYGKIDTIEIITDRQSGKKRGFGFVTFDDHDPVDKIVLQKYHTI 165
Query: 193 GSSRVDVKKALSKDEMEEIR 252
+V+KALS+ EM+E++
Sbjct: 166 NGHNAEVRKALSRQEMQEVQ 185
Score = 65.1 bits (157), Expect = 2e-10
Identities = 31/75 (41%), Positives = 46/75 (61%)
Frame = +1
Query: 13 GLKKDVTTEHLRHYFGSYGTITDCEIVTWKDSGESRGFGFVTFDDYDPVDKAILYKPHQI 192
GL + T E LR+Y+ +G +TDC ++ S SRGFGFVTF VD A+ +PH I
Sbjct: 15 GLSFETTEESLRNYYEQWGKLTDCVVMRDPASKRSRGFGFVTFSSMAEVDAAMAARPHSI 74
Query: 193 GSSRVDVKKALSKDE 237
V+ K+A++++E
Sbjct: 75 DGRVVEPKRAVAREE 89
>sp|Q22037|ROA1_CAEEL Heterogeneous nuclear ribonucleoprotein A1
Length = 346
Score = 87.0 bits (214), Expect = 6e-17
Identities = 40/86 (46%), Positives = 56/86 (65%)
Frame = +1
Query: 13 GLKKDVTTEHLRHYFGSYGTITDCEIVTWKDSGESRGFGFVTFDDYDPVDKAILYKPHQI 192
G+++D T + L YF YGT+T EI+ K + + RGFGFVTFDD+D VD+ +L K H +
Sbjct: 120 GVREDHTEDMLTEYFTKYGTVTKSEIILDKATQKPRGFGFVTFDDHDSVDQCVLQKSHMV 179
Query: 193 GSSRVDVKKALSKDEMEEIRRKQQNE 270
R DV+K LSKDEM + + + E
Sbjct: 180 NGHRCDVRKGLSKDEMSKAQMNRDRE 205
Score = 58.5 bits (140), Expect = 2e-08
Identities = 28/75 (37%), Positives = 43/75 (57%)
Frame = +1
Query: 13 GLKKDVTTEHLRHYFGSYGTITDCEIVTWKDSGESRGFGFVTFDDYDPVDKAILYKPHQI 192
GL + T + +R ++ +G ITD ++ + SRGFGFVTF VD A+ +PH I
Sbjct: 29 GLTSNTTDDLMREFYSQFGEITDIIVMRDPTTKRSRGFGFVTFSGKTEVDAAMKQRPHII 88
Query: 193 GSSRVDVKKALSKDE 237
VD K+A+ +D+
Sbjct: 89 DGKTVDPKRAVPRDD 103
>sp|P48810|RB87F_DROME Heterogeneous nuclear ribonucleoprotein 87F (HRP36.1 protein) (P11
protein)
Length = 385
Score = 85.1 bits (209), Expect = 2e-16
Identities = 40/77 (51%), Positives = 52/77 (67%)
Frame = +1
Query: 13 GLKKDVTTEHLRHYFGSYGTITDCEIVTWKDSGESRGFGFVTFDDYDPVDKAILYKPHQI 192
GL+ D E LR YF +G I IV+ KD+G+ RGF F+ FDDYDPVDK IL K H I
Sbjct: 121 GLRDDHDEECLREYFKDFGQIVSVNIVSDKDTGKKRGFAFIEFDDYDPVDKIILQKTHSI 180
Query: 193 GSSRVDVKKALSKDEME 243
+ +DVKKA++K +M+
Sbjct: 181 KNKTLDVKKAIAKQDMD 197
Score = 49.3 bits (116), Expect = 1e-05
Identities = 24/77 (31%), Positives = 42/77 (54%)
Frame = +1
Query: 13 GLKKDVTTEHLRHYFGSYGTITDCEIVTWKDSGESRGFGFVTFDDYDPVDKAILYKPHQI 192
GL T + L+ +F +G I D ++ + SRGFGF+T+ +D A +PH+I
Sbjct: 30 GLDYRTTDDGLKAHFEKWGNIVDVVVMKDPKTKRSRGFGFITYSQSYMIDNAQNARPHKI 89
Query: 193 GSSRVDVKKALSKDEME 243
V+ K+A+ + E++
Sbjct: 90 DGRTVEPKRAVPRQEID 106
>sp|P49312|ROA1_MOUSE Heterogeneous nuclear ribonucleoprotein A1 (Helix-destabilizing
protein) (Single-strand binding protein) (hnRNP core
protein A1) (HDP-1) (Topoisomerase-inhibitor suppressed)
Length = 320
Score = 84.7 bits (208), Expect = 3e-16
Identities = 42/91 (46%), Positives = 54/91 (59%)
Frame = +1
Query: 13 GLKKDVTTEHLRHYFGSYGTITDCEIVTWKDSGESRGFGFVTFDDYDPVDKAILYKPHQI 192
G+K+D HLR YF YG I EI+T + SG+ RGF FVTFDD+D VDK ++ K H +
Sbjct: 111 GIKEDTEEHHLRDYFEQYGKIEVIEIMTDRGSGKKRGFAFVTFDDHDSVDKIVIQKYHTV 170
Query: 193 GSSRVDVKKALSKDEMEEIRRKQQNEPLSVN 285
+V+KALSK EM Q+ S N
Sbjct: 171 NGHNCEVRKALSKQEMASASSSQRGRSGSGN 201
Score = 64.7 bits (156), Expect = 3e-10
Identities = 29/77 (37%), Positives = 50/77 (64%)
Frame = +1
Query: 13 GLKKDVTTEHLRHYFGSYGTITDCEIVTWKDSGESRGFGFVTFDDYDPVDKAILYKPHQI 192
GL + T E LR +F +GT+TDC ++ ++ SRGFGFVT+ + VD A+ +PH++
Sbjct: 20 GLSFETTDESLRSHFEQWGTLTDCVVMRDPNTKRSRGFGFVTYATVEEVDAAMNARPHKV 79
Query: 193 GSSRVDVKKALSKDEME 243
V+ K+A+S+++ +
Sbjct: 80 DGRVVEPKRAVSREDSQ 96
>sp|P09651|ROA1_HUMAN Heterogeneous nuclear ribonucleoprotein A1 (Helix-destabilizing
protein) (Single-strand binding protein) (hnRNP core
protein A1)
Length = 372
Score = 84.7 bits (208), Expect = 3e-16
Identities = 42/91 (46%), Positives = 54/91 (59%)
Frame = +1
Query: 13 GLKKDVTTEHLRHYFGSYGTITDCEIVTWKDSGESRGFGFVTFDDYDPVDKAILYKPHQI 192
G+K+D HLR YF YG I EI+T + SG+ RGF FVTFDD+D VDK ++ K H +
Sbjct: 111 GIKEDTEEHHLRDYFEQYGKIEVIEIMTDRGSGKKRGFAFVTFDDHDSVDKIVIQKYHTV 170
Query: 193 GSSRVDVKKALSKDEMEEIRRKQQNEPLSVN 285
+V+KALSK EM Q+ S N
Sbjct: 171 NGHNCEVRKALSKQEMASASSSQRGRSGSGN 201
Score = 64.7 bits (156), Expect = 3e-10
Identities = 29/77 (37%), Positives = 50/77 (64%)
Frame = +1
Query: 13 GLKKDVTTEHLRHYFGSYGTITDCEIVTWKDSGESRGFGFVTFDDYDPVDKAILYKPHQI 192
GL + T E LR +F +GT+TDC ++ ++ SRGFGFVT+ + VD A+ +PH++
Sbjct: 20 GLSFETTDESLRSHFEQWGTLTDCVVMRDPNTKRSRGFGFVTYATVEEVDAAMNARPHKV 79
Query: 193 GSSRVDVKKALSKDEME 243
V+ K+A+S+++ +
Sbjct: 80 DGRVVEPKRAVSREDSQ 96
>sp|P17130|ROA1_XENLA Heterogeneous nuclear ribonucleoproteins A1 homolog (hnRNP A1)
(Helix-destabilizing protein) (Single-strand binding
protein) (hnRNP core protein A1)
Length = 365
Score = 84.3 bits (207), Expect = 4e-16
Identities = 41/91 (45%), Positives = 56/91 (61%)
Frame = +1
Query: 13 GLKKDVTTEHLRHYFGSYGTITDCEIVTWKDSGESRGFGFVTFDDYDPVDKAILYKPHQI 192
G+K+D +HLR YF YG I EI+T + SG+ RGF FVTF+D+D VDK ++ K H +
Sbjct: 111 GIKEDTEEDHLREYFEQYGKIEVIEIMTDRGSGKKRGFAFVTFEDHDSVDKIVIQKYHTV 170
Query: 193 GSSRVDVKKALSKDEMEEIRRKQQNEPLSVN 285
+ V+KALSK EM + Q+ S N
Sbjct: 171 NNHNSQVRKALSKQEMASVSGSQRERGGSGN 201
Score = 67.4 bits (163), Expect = 5e-11
Identities = 31/75 (41%), Positives = 49/75 (65%)
Frame = +1
Query: 13 GLKKDVTTEHLRHYFGSYGTITDCEIVTWKDSGESRGFGFVTFDDYDPVDKAILYKPHQI 192
GL + T E LR +F +GT+TDC ++ +S SRGFGFVT+ D VD A+ +PH++
Sbjct: 20 GLSFETTDESLREHFEQWGTLTDCVVMRDPNSKRSRGFGFVTYLSTDEVDAAMTARPHKV 79
Query: 193 GSSRVDVKKALSKDE 237
V+ K+A+S+++
Sbjct: 80 DGRVVEPKRAVSRED 94
>sp|P09867|ROA1_BOVIN Heterogeneous nuclear ribonucleoprotein A1 (Helix-destabilizing
protein) (Single-strand binding protein) (hnRNP core
protein A1) (Unwinding protein 1) (UP1)
Length = 195
Score = 84.0 bits (206), Expect = 5e-16
Identities = 40/84 (47%), Positives = 52/84 (61%)
Frame = +1
Query: 13 GLKKDVTTEHLRHYFGSYGTITDCEIVTWKDSGESRGFGFVTFDDYDPVDKAILYKPHQI 192
G+K+D HLR YF YG I EI+T + SG+ RGF FVTFDD+D VDK ++ K H +
Sbjct: 110 GIKEDTEEHHLRDYFEQYGKIEVIEIMTDRGSGKKRGFAFVTFDDHDSVDKIVIQKYHTV 169
Query: 193 GSSRVDVKKALSKDEMEEIRRKQQ 264
+V+KALSK EM Q+
Sbjct: 170 NGHNCEVRKALSKQEMASASSSQR 193
Score = 64.7 bits (156), Expect = 3e-10
Identities = 29/77 (37%), Positives = 50/77 (64%)
Frame = +1
Query: 13 GLKKDVTTEHLRHYFGSYGTITDCEIVTWKDSGESRGFGFVTFDDYDPVDKAILYKPHQI 192
GL + T E LR +F +GT+TDC ++ ++ SRGFGFVT+ + VD A+ +PH++
Sbjct: 19 GLSFETTDESLRSHFEQWGTLTDCVVMRDPNTKRSRGFGFVTYATVEEVDAAMNARPHKV 78
Query: 193 GSSRVDVKKALSKDEME 243
V+ K+A+S+++ +
Sbjct: 79 DGRVVEPKRAVSREDSQ 95
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 86,169,644
Number of Sequences: 369166
Number of extensions: 1647996
Number of successful extensions: 4552
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4271
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4523
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 8550075140
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)