Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_009_K08
(688 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P48721|GRP75_RAT Stress-70 protein, mitochondrial precur... 331 1e-90
sp|P38646|GRP75_HUMAN Stress-70 protein, mitochondrial prec... 330 2e-90
sp|P38647|GRP75_MOUSE Stress-70 protein, mitochondrial prec... 330 2e-90
sp|P29845|HSP7E_DROME Heat shock 70 kDa protein cognate 5 330 2e-90
sp|O35501|GRP75_CRIGR Stress-70 protein, mitochondrial prec... 330 3e-90
sp|P11141|HSP7F_CAEEL Heat shock 70 kDa protein F, mitochon... 323 3e-88
sp|Q01899|HSP7M_PHAVU Heat shock 70 kDa protein, mitochondr... 275 1e-73
sp|P37900|HSP7M_PEA Heat shock 70 kDa protein, mitochondria... 270 3e-72
sp|Q8YE76|DNAK_BRUME Chaperone protein dnaK (Heat shock pro... 270 3e-72
sp|P42374|DNAK_RHIME Chaperone protein dnaK (Heat shock pro... 269 6e-72
>sp|P48721|GRP75_RAT Stress-70 protein, mitochondrial precursor (75 kDa glucose regulated
protein) (GRP 75) (Peptide-binding protein 74) (PBP74)
(MTHSP70) (Mortalin)
Length = 679
Score = 331 bits (848), Expect = 1e-90
Identities = 169/226 (74%), Positives = 190/226 (84%)
Frame = +3
Query: 3 GGMTRMPRVQETVQKLFGRVPSKSVNPDEAVAMGAAIQXXXXXXXXXXXXXXXXXXXXXX 182
GGMTRMP+VQ+TVQ LFGR PSK+VNPDEAVA+GAAIQ
Sbjct: 387 GGMTRMPKVQQTVQDLFGRAPSKAVNPDEAVAIGAAIQGGVLAGDVTDVLLLDVTPLSLG 446
Query: 183 IETLGGVFTKLINRNTTIPTKKSQVFSTAADGQTQVEIKVHQGEREMAADNKILGQFSLI 362
IETLGGVFTKLINRNTTIPTKKSQVFSTAADGQTQVEIKV QGEREMA DNK+LGQF+LI
Sbjct: 447 IETLGGVFTKLINRNTTIPTKKSQVFSTAADGQTQVEIKVCQGEREMAGDNKLLGQFTLI 506
Query: 363 GIPPAPRGVPQIEVTFDIDANGIVNVSARDKGTGKEQQIVIHSSGGLSKDEIENMIKRAE 542
GIPPAPRGVPQIEVTFDIDANGIV+VSA+DKGTG+EQQIVI SSGGLSKD+IENM+K AE
Sbjct: 507 GIPPAPRGVPQIEVTFDIDANGIVHVSAKDKGTGREQQIVIQSSGGLSKDDIENMVKNAE 566
Query: 543 ENAENDKRKREMGEVVYQAEGIVYDTESKIDEFKNQLPAEECEKLR 680
+ AE D+RK+E E V AEGIV+DTE+K++EFK+QLPA+EC KL+
Sbjct: 567 KYAEEDRRKKERVEAVNMAEGIVHDTETKMEEFKDQLPADECNKLK 612
>sp|P38646|GRP75_HUMAN Stress-70 protein, mitochondrial precursor (75 kDa glucose regulated
protein) (GRP 75) (Peptide-binding protein 74) (PBP74)
(Mortalin) (MOT)
Length = 679
Score = 330 bits (847), Expect = 2e-90
Identities = 168/226 (74%), Positives = 190/226 (84%)
Frame = +3
Query: 3 GGMTRMPRVQETVQKLFGRVPSKSVNPDEAVAMGAAIQXXXXXXXXXXXXXXXXXXXXXX 182
GGMTRMP+VQ+TVQ LFGR PSK+VNPDEAVA+GAAIQ
Sbjct: 387 GGMTRMPKVQQTVQDLFGRAPSKAVNPDEAVAIGAAIQGGVLAGDVTDVLLLDVTPLSLG 446
Query: 183 IETLGGVFTKLINRNTTIPTKKSQVFSTAADGQTQVEIKVHQGEREMAADNKILGQFSLI 362
IETLGGVFTKLINRNTTIPTKKSQVFSTAADGQTQVEIKV QGEREMA DNK+LGQF+LI
Sbjct: 447 IETLGGVFTKLINRNTTIPTKKSQVFSTAADGQTQVEIKVCQGEREMAGDNKLLGQFTLI 506
Query: 363 GIPPAPRGVPQIEVTFDIDANGIVNVSARDKGTGKEQQIVIHSSGGLSKDEIENMIKRAE 542
GIPPAPRGVPQIEVTFDIDANGIV+VSA+DKGTG+EQQIVI SSGGLSKD+IENM+K AE
Sbjct: 507 GIPPAPRGVPQIEVTFDIDANGIVHVSAKDKGTGREQQIVIQSSGGLSKDDIENMVKNAE 566
Query: 543 ENAENDKRKREMGEVVYQAEGIVYDTESKIDEFKNQLPAEECEKLR 680
+ AE D+RK+E E V AEGI++DTE+K++EFK+QLPA+EC KL+
Sbjct: 567 KYAEEDRRKKERVEAVNMAEGIIHDTETKMEEFKDQLPADECNKLK 612
>sp|P38647|GRP75_MOUSE Stress-70 protein, mitochondrial precursor (75 kDa glucose regulated
protein) (GRP 75) (Peptide-binding protein 74) (PBP74)
(P66 MOT) (Mortalin)
Length = 679
Score = 330 bits (847), Expect = 2e-90
Identities = 168/226 (74%), Positives = 190/226 (84%)
Frame = +3
Query: 3 GGMTRMPRVQETVQKLFGRVPSKSVNPDEAVAMGAAIQXXXXXXXXXXXXXXXXXXXXXX 182
GGMTRMP+VQ+TVQ LFGR PSK+VNPDEAVA+GAAIQ
Sbjct: 387 GGMTRMPKVQQTVQDLFGRAPSKAVNPDEAVAIGAAIQGGVLAGDVTDVLLLDVTPLSLG 446
Query: 183 IETLGGVFTKLINRNTTIPTKKSQVFSTAADGQTQVEIKVHQGEREMAADNKILGQFSLI 362
IETLGGVFTKLINRNTTIPTKKSQVFSTAADGQTQVEIKV QGEREMA DNK+LGQF+LI
Sbjct: 447 IETLGGVFTKLINRNTTIPTKKSQVFSTAADGQTQVEIKVCQGEREMAGDNKLLGQFTLI 506
Query: 363 GIPPAPRGVPQIEVTFDIDANGIVNVSARDKGTGKEQQIVIHSSGGLSKDEIENMIKRAE 542
GIPPAPRGVPQIEVTFDIDANGIV+VSA+DKGTG+EQQIVI SSGGLSKD+IENM+K AE
Sbjct: 507 GIPPAPRGVPQIEVTFDIDANGIVHVSAKDKGTGREQQIVIQSSGGLSKDDIENMVKNAE 566
Query: 543 ENAENDKRKREMGEVVYQAEGIVYDTESKIDEFKNQLPAEECEKLR 680
+ AE D+RK+E E V AEGI++DTE+K++EFK+QLPA+EC KL+
Sbjct: 567 KYAEEDRRKKERVEAVNMAEGIIHDTETKMEEFKDQLPADECNKLK 612
>sp|P29845|HSP7E_DROME Heat shock 70 kDa protein cognate 5
Length = 686
Score = 330 bits (847), Expect = 2e-90
Identities = 168/226 (74%), Positives = 191/226 (84%)
Frame = +3
Query: 3 GGMTRMPRVQETVQKLFGRVPSKSVNPDEAVAMGAAIQXXXXXXXXXXXXXXXXXXXXXX 182
GGMTRMP+VQ TVQ+LFGR PS+SVNPDEAVA+GAA+Q
Sbjct: 387 GGMTRMPKVQSTVQELFGRQPSRSVNPDEAVAVGAAVQGGVLAGDVTDVLLLDVTPLSLG 446
Query: 183 IETLGGVFTKLINRNTTIPTKKSQVFSTAADGQTQVEIKVHQGEREMAADNKILGQFSLI 362
IETLGGVFT+LI+RNTTIPTKKSQVFSTA+DGQTQVEIKVHQGEREMA DNK+LG F+L+
Sbjct: 447 IETLGGVFTRLISRNTTIPTKKSQVFSTASDGQTQVEIKVHQGEREMANDNKLLGSFTLV 506
Query: 363 GIPPAPRGVPQIEVTFDIDANGIVNVSARDKGTGKEQQIVIHSSGGLSKDEIENMIKRAE 542
GIPPAPRGVPQIEV FDIDANGIV+VSA+DKGTGKEQQIVI SSGGLSKDEIENMIK+AE
Sbjct: 507 GIPPAPRGVPQIEVVFDIDANGIVHVSAKDKGTGKEQQIVIQSSGGLSKDEIENMIKKAE 566
Query: 543 ENAENDKRKREMGEVVYQAEGIVYDTESKIDEFKNQLPAEECEKLR 680
E A DK+KRE+ E+V Q E IV+DTE+K++EFK+QLPAEECEKL+
Sbjct: 567 EYATADKQKRELIEIVNQGESIVHDTETKMEEFKSQLPAEECEKLK 612
>sp|O35501|GRP75_CRIGR Stress-70 protein, mitochondrial precursor (75 kDa glucose regulated
protein) (GRP 75)
Length = 679
Score = 330 bits (845), Expect = 3e-90
Identities = 167/226 (73%), Positives = 190/226 (84%)
Frame = +3
Query: 3 GGMTRMPRVQETVQKLFGRVPSKSVNPDEAVAMGAAIQXXXXXXXXXXXXXXXXXXXXXX 182
GGMTRMP+VQ+TVQ LFGR PSK+VNPDEAVA+GAAIQ
Sbjct: 387 GGMTRMPKVQQTVQDLFGRAPSKAVNPDEAVAIGAAIQGGVLAGDVTDVLLLDVTPLSLG 446
Query: 183 IETLGGVFTKLINRNTTIPTKKSQVFSTAADGQTQVEIKVHQGEREMAADNKILGQFSLI 362
IETLGGVFTKLINRNTTIPTKKSQVFSTAADGQTQVEIKV QGEREMA DNK+LGQF+LI
Sbjct: 447 IETLGGVFTKLINRNTTIPTKKSQVFSTAADGQTQVEIKVCQGEREMAGDNKLLGQFTLI 506
Query: 363 GIPPAPRGVPQIEVTFDIDANGIVNVSARDKGTGKEQQIVIHSSGGLSKDEIENMIKRAE 542
GIPPAPRGVPQIEVTFD+DANGIV+VSA+DKGTG+EQQIVI SSGGLSKD+IENM+K AE
Sbjct: 507 GIPPAPRGVPQIEVTFDLDANGIVHVSAKDKGTGREQQIVIQSSGGLSKDDIENMVKNAE 566
Query: 543 ENAENDKRKREMGEVVYQAEGIVYDTESKIDEFKNQLPAEECEKLR 680
+ AE D+RK+E E V AEGI++DTE+K++EFK+QLPA+EC KL+
Sbjct: 567 KYAEEDRRKKERVEAVNMAEGIIHDTETKMEEFKDQLPADECNKLK 612
>sp|P11141|HSP7F_CAEEL Heat shock 70 kDa protein F, mitochondrial precursor
Length = 657
Score = 323 bits (827), Expect = 3e-88
Identities = 162/226 (71%), Positives = 187/226 (82%)
Frame = +3
Query: 3 GGMTRMPRVQETVQKLFGRVPSKSVNPDEAVAMGAAIQXXXXXXXXXXXXXXXXXXXXXX 182
GGM+RMP+VQ TVQ++FG+VPSK+VNPDEAVAMGAAIQ
Sbjct: 366 GGMSRMPKVQATVQEIFGKVPSKAVNPDEAVAMGAAIQGAVLAGDVTDVLLLDVTPLSLG 425
Query: 183 IETLGGVFTKLINRNTTIPTKKSQVFSTAADGQTQVEIKVHQGEREMAADNKILGQFSLI 362
IETLGG+ TKLI RNTTIPTKKSQVFSTAADGQTQV+IKV QGEREMA NK+LGQFSL+
Sbjct: 426 IETLGGIMTKLITRNTTIPTKKSQVFSTAADGQTQVQIKVFQGEREMATSNKLLGQFSLV 485
Query: 363 GIPPAPRGVPQIEVTFDIDANGIVNVSARDKGTGKEQQIVIHSSGGLSKDEIENMIKRAE 542
GIPPAPRGVPQ+EVTFDIDANGIVNVSARD+GTGKEQQIVI SSGGLSKD+IENMIK AE
Sbjct: 486 GIPPAPRGVPQVEVTFDIDANGIVNVSARDRGTGKEQQIVIQSSGGLSKDQIENMIKEAE 545
Query: 543 ENAENDKRKREMGEVVYQAEGIVYDTESKIDEFKNQLPAEECEKLR 680
+NA D +++E+ EV+ QAEGI++DTE+K+ EF +QLP +ECE LR
Sbjct: 546 KNAAEDAKRKELVEVINQAEGIIHDTEAKMTEFADQLPKDECEALR 591
>sp|Q01899|HSP7M_PHAVU Heat shock 70 kDa protein, mitochondrial precursor
Length = 675
Score = 275 bits (702), Expect = 1e-73
Identities = 137/227 (60%), Positives = 171/227 (75%)
Frame = +3
Query: 3 GGMTRMPRVQETVQKLFGRVPSKSVNPDEAVAMGAAIQXXXXXXXXXXXXXXXXXXXXXX 182
GGMTR+P+VQE V +FG+ PSK VNPDEAVAMGAAIQ
Sbjct: 384 GGMTRVPKVQEVVLNIFGKSPSKGVNPDEAVAMGAAIQGGILRGDVKELLLLDVTPLSLG 443
Query: 183 IETLGGVFTKLINRNTTIPTKKSQVFSTAADGQTQVEIKVHQGEREMAADNKILGQFSLI 362
IETLGG+FT+LINRNTTIPTKKSQVFSTAAD QTQV IKV QGEREMA+DNK+LG+F L+
Sbjct: 444 IETLGGIFTRLINRNTTIPTKKSQVFSTAADNQTQVGIKVLQGEREMASDNKMLGEFDLV 503
Query: 363 GIPPAPRGVPQIEVTFDIDANGIVNVSARDKGTGKEQQIVIHSSGGLSKDEIENMIKRAE 542
GIPPAPRG+PQIEVTFDIDANGIV VSA+DK TGKEQQI I SSGGLS+DEIE M+K AE
Sbjct: 504 GIPPAPRGLPQIEVTFDIDANGIVTVSAKDKSTGKEQQITIRSSGGLSEDEIEKMVKEAE 563
Query: 543 ENAENDKRKREMGEVVYQAEGIVYDTESKIDEFKNQLPAEECEKLRN 683
+A+ D+ ++ + ++ A+ +Y E + E++ ++P+E +++ +
Sbjct: 564 LHAQKDQERKTLIDIRNSADTTIYSIEKSLGEYREKIPSETAKEIED 610
>sp|P37900|HSP7M_PEA Heat shock 70 kDa protein, mitochondrial precursor
Length = 675
Score = 270 bits (690), Expect = 3e-72
Identities = 135/227 (59%), Positives = 170/227 (74%)
Frame = +3
Query: 3 GGMTRMPRVQETVQKLFGRVPSKSVNPDEAVAMGAAIQXXXXXXXXXXXXXXXXXXXXXX 182
GGMTR+P+VQ+ V ++FG+ PSK VNPDEAVAMGAA+Q
Sbjct: 385 GGMTRVPKVQQVVSEIFGKSPSKGVNPDEAVAMGAALQGGILRGDVKELLLLDVTPLSLG 444
Query: 183 IETLGGVFTKLINRNTTIPTKKSQVFSTAADGQTQVEIKVHQGEREMAADNKILGQFSLI 362
IETLGG+FT+LI+RNTTIPTKKSQVFSTAAD QTQV IKV QGEREMAADNK LG+F L+
Sbjct: 445 IETLGGIFTRLISRNTTIPTKKSQVFSTAADNQTQVGIKVLQGEREMAADNKSLGEFDLV 504
Query: 363 GIPPAPRGVPQIEVTFDIDANGIVNVSARDKGTGKEQQIVIHSSGGLSKDEIENMIKRAE 542
GIPPAPRG+PQIEVTFDIDANGIV VSA+DK TGKEQQI I SSGGLS DEI+ M+K AE
Sbjct: 505 GIPPAPRGLPQIEVTFDIDANGIVTVSAKDKSTGKEQQITIRSSGGLSDDEIDKMVKEAE 564
Query: 543 ENAENDKRKREMGEVVYQAEGIVYDTESKIDEFKNQLPAEECEKLRN 683
+A+ D+ ++ + ++ A+ +Y E + E++ ++PAE +++ +
Sbjct: 565 LHAQRDQERKALIDIRNSADTSIYSIEKSLAEYREKIPAEVAKEIED 611
>sp|Q8YE76|DNAK_BRUME Chaperone protein dnaK (Heat shock protein 70) (Heat shock 70 kDa
protein) (HSP70)
Length = 637
Score = 270 bits (690), Expect = 3e-72
Identities = 139/221 (62%), Positives = 163/221 (73%)
Frame = +3
Query: 3 GGMTRMPRVQETVQKLFGRVPSKSVNPDEAVAMGAAIQXXXXXXXXXXXXXXXXXXXXXX 182
GGMTRMP++QE V+ FG+ P K VNPDE VAMGAAIQ
Sbjct: 336 GGMTRMPKIQEVVKAFFGKEPHKGVNPDEVVAMGAAIQGGVLQGDVKDVLLLDVTPLSLG 395
Query: 183 IETLGGVFTKLINRNTTIPTKKSQVFSTAADGQTQVEIKVHQGEREMAADNKILGQFSLI 362
IETLGGVFT+LI RNTTIPTKKSQ FSTA D Q+ V I+V QGEREMAADNK+LGQF L+
Sbjct: 396 IETLGGVFTRLIERNTTIPTKKSQTFSTAEDNQSAVTIRVFQGEREMAADNKLLGQFDLV 455
Query: 363 GIPPAPRGVPQIEVTFDIDANGIVNVSARDKGTGKEQQIVIHSSGGLSKDEIENMIKRAE 542
GIPPAPRGVPQIEVTFDIDANGIVNVSA+DKGTGKE QI I +SGGLS +IE M+K AE
Sbjct: 456 GIPPAPRGVPQIEVTFDIDANGIVNVSAKDKGTGKEHQIRIQASGGLSDADIEKMVKDAE 515
Query: 543 ENAENDKRKREMGEVVYQAEGIVYDTESKIDEFKNQLPAEE 665
NAE DK++RE E QAE +V+ TE + E+ +++ A++
Sbjct: 516 ANAEADKKRRESVEAKNQAESLVHSTEKSLAEYGDKVSADD 556
>sp|P42374|DNAK_RHIME Chaperone protein dnaK (Heat shock protein 70) (Heat shock 70 kDa
protein) (HSP70)
Length = 641
Score = 269 bits (687), Expect = 6e-72
Identities = 141/212 (66%), Positives = 159/212 (75%)
Frame = +3
Query: 3 GGMTRMPRVQETVQKLFGRVPSKSVNPDEAVAMGAAIQXXXXXXXXXXXXXXXXXXXXXX 182
GGMTRMP+VQETV++LFG+ P K VNPDE VAMGAAIQ
Sbjct: 336 GGMTRMPKVQETVKQLFGKEPHKGVNPDEVVAMGAAIQAGVLQGDVKDVLLLDVTPLSLG 395
Query: 183 IETLGGVFTKLINRNTTIPTKKSQVFSTAADGQTQVEIKVHQGEREMAADNKILGQFSLI 362
IETLGGVFT+LI RNTTIPTKKSQVFSTA D Q+ V I+V QGEREMAADNK+LGQF L+
Sbjct: 396 IETLGGVFTRLIERNTTIPTKKSQVFSTADDNQSAVTIRVSQGEREMAADNKLLGQFDLV 455
Query: 363 GIPPAPRGVPQIEVTFDIDANGIVNVSARDKGTGKEQQIVIHSSGGLSKDEIENMIKRAE 542
GIPPAPRGVPQIEVTFDIDANGIV VSA+DKGTGKE QI I +SGGLS EIE M+K AE
Sbjct: 456 GIPPAPRGVPQIEVTFDIDANGIVQVSAKDKGTGKEHQIRIQASGGLSDAEIEKMVKDAE 515
Query: 543 ENAENDKRKREMGEVVYQAEGIVYDTESKIDE 638
NAE DK++RE E QAE +V+ +E + E
Sbjct: 516 ANAEADKKRREGVEAKNQAESLVHSSEKSLQE 547
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 67,486,467
Number of Sequences: 369166
Number of extensions: 1214185
Number of successful extensions: 5079
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4419
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4553
length of database: 68,354,980
effective HSP length: 107
effective length of database: 48,588,335
effective search space used: 5879188535
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)