Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_009_J21
(609 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q06561|UNC52_CAEEL Basement membrane proteoglycan precur... 106 4e-23
sp|P98160|PGBM_HUMAN Basement membrane-specific heparan sul... 102 1e-21
sp|Q05793|PGBM_MOUSE Basement membrane-specific heparan sul... 100 4e-21
sp|P98164|LRP2_HUMAN Low-density lipoprotein receptor-relat... 71 2e-12
sp|P98157|LRP1_CHICK Low-density lipoprotein receptor-relat... 70 3e-12
sp|Q9NZR2|LRP1B_HUMAN Low-density lipoprotein receptor-rela... 69 9e-12
sp|Q9JI18|LRP1B_MOUSE Low-density lipoprotein receptor-rela... 67 4e-11
sp|Q07954|LRP1_HUMAN Low-density lipoprotein receptor-relat... 67 4e-11
sp|P05156|CFAI_HUMAN Complement factor I precursor (C3B/C4B... 67 5e-11
sp|P98158|LRP2_RAT Low-density lipoprotein receptor-related... 67 5e-11
>sp|Q06561|UNC52_CAEEL Basement membrane proteoglycan precursor (Perlecan homolog)
(Uncoordinated protein 52)
Length = 3375
Score = 106 bits (265), Expect = 4e-23
Identities = 53/152 (34%), Positives = 81/152 (53%), Gaps = 3/152 (1%)
Frame = +2
Query: 29 WKCDGENDCGNNFDESRCTE--TDNMCNNVKFNCKDGK-VIPRAYQCDKEADCVNGDDEI 199
W CDG++DCG+N DE C + + C +F C D + +P ++ CD DC +G DE+
Sbjct: 207 WLCDGDDDCGDNSDELNCNAKPSSSDCKPTEFQCHDRRQCVPSSFHCDGTNDCHDGSDEV 266
Query: 200 GCVLPQVTSTTSDKVKRVRRGSSLELKCESYGVPRPHVVWRFNWGCLKDNLRMPVTTQIE 379
GCV P V ++ V RG++ L C++ VP P++ WR NWG + + R ++
Sbjct: 267 GCVQPTVVDPPQTNLQ-VPRGTTFSLTCKAVAVPEPYINWRLNWGPVCEPPRC-----LQ 320
Query: 380 NCNKVISTLRIINFQPGDDGIYNCESLSGPNR 475
TL I + QP D G Y CE+++ R
Sbjct: 321 TSEGGYGTLTIHDAQPVDQGAYTCEAINVKGR 352
Score = 30.8 bits (68), Expect = 2.8
Identities = 29/100 (29%), Positives = 45/100 (45%), Gaps = 6/100 (6%)
Frame = +2
Query: 182 NGDDEIGCVLPQVTSTTSDKVKRVRRGSSLELKCESYGV---PRPHVVWRFNWGCLKDNL 352
+G+ IG L T+ K+ V G L++KCE++G P P V W + G + +L
Sbjct: 1966 HGNVNIGPSLTVKTNPPGPKLI-VTVGEPLQVKCEAFGAPGDPEPEVEWLHDPGPERGDL 2024
Query: 353 R---MPVTTQIENCNKVISTLRIINFQPGDDGIYNCESLS 463
PVT + +R N G+ G+Y C+ S
Sbjct: 2025 PDDFKPVTISEQ-------FIRHPNVGLGNAGVYTCKGSS 2057
>sp|P98160|PGBM_HUMAN Basement membrane-specific heparan sulfate proteoglycan core
protein precursor (HSPG) (Perlecan) (PLC)
Length = 4391
Score = 102 bits (253), Expect = 1e-21
Identities = 50/154 (32%), Positives = 82/154 (53%), Gaps = 3/154 (1%)
Frame = +2
Query: 29 WKCDGENDCGNNFDESRCT--ETDNMCNNVKFNCKDGKV-IPRAYQCDKEADCVNGDDEI 199
W+CDG+ DC + DE+ C + +C +F C + IP ++ CD+E+DC + DE
Sbjct: 342 WRCDGDFDCEDRTDEANCPTKRPEEVCGPTQFRCVSTNMCIPASFHCDEESDCPDRSDEF 401
Query: 200 GCVLPQVTSTTSDKVKRVRRGSSLELKCESYGVPRPHVVWRFNWGCLKDNLRMPVTTQIE 379
GC+ PQV + + + + RG ++ C + GVP P + WR NWG + + R+ VT++
Sbjct: 402 GCMPPQVVTPpreSI-QASRGQTVTFTCVAIGVPTPIINWRLNWGHIPSHPRVTVTSEGG 460
Query: 380 NCNKVISTLRIINFQPGDDGIYNCESLSGPNRSF 481
TL I + + D G Y CE+++ F
Sbjct: 461 R-----GTLIIRDVKESDQGAYTCEAMNARGMVF 489
Score = 40.4 bits (93), Expect = 0.004
Identities = 16/38 (42%), Positives = 22/38 (57%)
Frame = +2
Query: 101 CNNVKFNCKDGKVIPRAYQCDKEADCVNGDDEIGCVLP 214
C + C++G IPR Y CD + DC +G DE+ C P
Sbjct: 285 CGPQEAACRNGHCIPRDYLCDGQEDCEDGSDELDCGPP 322
Score = 32.7 bits (73), Expect = 0.74
Identities = 22/72 (30%), Positives = 29/72 (40%)
Frame = +2
Query: 248 RVRRGSSLELKCESYGVPRPHVVWRFNWGCLKDNLRMPVTTQIENCNKVISTLRIINFQP 427
+V G ++ L C + GVP + WR G L R T I+TL I
Sbjct: 1966 QVHAGRTVRLYCRAAGVPSATITWRKEGGSLPPQARSERTD--------IATLLIPAITT 2017
Query: 428 GDDGIYNCESLS 463
D G Y C + S
Sbjct: 2018 ADAGFYLCVATS 2029
Score = 32.0 bits (71), Expect = 1.3
Identities = 25/78 (32%), Positives = 31/78 (39%), Gaps = 2/78 (2%)
Frame = +2
Query: 251 VRRGSSLELKCESYGVPRPHVVWRFNWGCLKDNLRMPVTTQIENCNKVISTLRIINFQPG 430
V G +L+L C G V W G L P TQ+ S LR+ P
Sbjct: 2062 VTEGQTLDLNCVVAGSAHAQVTWYRRGGSL------PPHTQVHG-----SRLRLPQVSPA 2110
Query: 431 DDGIYNC--ESLSGPNRS 478
D G Y C E+ SGP +
Sbjct: 2111 DSGEYVCRVENGSGPKEA 2128
Score = 32.0 bits (71), Expect = 1.3
Identities = 20/69 (28%), Positives = 27/69 (39%)
Frame = +2
Query: 248 RVRRGSSLELKCESYGVPRPHVVWRFNWGCLKDNLRMPVTTQIENCNKVISTLRIINFQP 427
RV G +L+LKC G V W G +P Q+ LR+ P
Sbjct: 2837 RVAEGQTLDLKCVVPGQAHAQVTWHKRGG------NLPARHQVHG-----PLLRLNQVSP 2885
Query: 428 GDDGIYNCE 454
D G Y+C+
Sbjct: 2886 ADSGEYSCQ 2894
Score = 31.2 bits (69), Expect = 2.2
Identities = 23/73 (31%), Positives = 27/73 (36%)
Frame = +2
Query: 251 VRRGSSLELKCESYGVPRPHVVWRFNWGCLKDNLRMPVTTQIENCNKVISTLRIINFQPG 430
V G +L+L C G V W G L P Q S LR+ P
Sbjct: 2936 VTEGQTLDLNCVVPGQAHAQVTWYKRGGSL------PARHQTHG-----SQLRLHLVSPA 2984
Query: 431 DDGIYNCESLSGP 469
D G Y C + SGP
Sbjct: 2985 DSGEYVCRAASGP 2997
Score = 30.8 bits (68), Expect = 2.8
Identities = 23/98 (23%), Positives = 38/98 (38%)
Frame = +2
Query: 209 LPQVTSTTSDKVKRVRRGSSLELKCESYGVPRPHVVWRFNWGCLKDNLRMPVTTQIENCN 388
LP V V+ V G ++E +C + G P+P V W G L+ +
Sbjct: 3486 LPSVLINIRTSVQTVVVGHAVEFECLALGDPKPQVTWSKVGGHLRPGIVQSG-------- 3537
Query: 389 KVISTLRIINFQPGDDGIYNCESLSGPNRSFSEDYQLI 502
+RI + + D G Y C + + + S L+
Sbjct: 3538 ---GVVRIAHVELADAGQYRCTATNAAGTTQSHVLLLV 3572
Score = 30.4 bits (67), Expect = 3.7
Identities = 12/39 (30%), Positives = 19/39 (48%), Gaps = 1/39 (2%)
Frame = +2
Query: 101 CNNVKFNCKD-GKVIPRAYQCDKEADCVNGDDEIGCVLP 214
C +F C + + Y+CD+ DC + DE+ C P
Sbjct: 199 CTEAEFACHSYNECVALEYRCDRRPDCRDMSDELNCEEP 237
Score = 30.4 bits (67), Expect = 3.7
Identities = 24/82 (29%), Positives = 31/82 (37%)
Frame = +2
Query: 206 VLPQVTSTTSDKVKRVRRGSSLELKCESYGVPRPHVVWRFNWGCLKDNLRMPVTTQIENC 385
V P V +S +V G +L+L C G V W G L P Q+
Sbjct: 2435 VTPTVRIESSSS--QVAEGQTLDLNCLVAGQAHAQVTWHKRGGSL------PARHQVHG- 2485
Query: 386 NKVISTLRIINFQPGDDGIYNC 451
S LR++ P D G Y C
Sbjct: 2486 ----SRLRLLQVTPADSGEYVC 2503
Score = 30.0 bits (66), Expect = 4.8
Identities = 27/81 (33%), Positives = 37/81 (45%), Gaps = 2/81 (2%)
Frame = +2
Query: 251 VRRGSSLELKCESYGVPRPHVVWRFNWGCLKDNLRMPVTTQIENCNKVISTLRIINFQPG 430
V +G S L+C+ G P PH F W +D +P TQ + S L + QP
Sbjct: 1688 VPQGGSHSLRCQVSGSP-PHY---FYWS-REDGRPVPSGTQQRHQG---SELHFPSVQPS 1739
Query: 431 DDGIY--NCESLSGPNRSFSE 487
D G+Y C +L N S +E
Sbjct: 1740 DAGVYICTCRNLHQSNTSRAE 1760
Score = 29.6 bits (65), Expect = 6.3
Identities = 22/71 (30%), Positives = 26/71 (36%)
Frame = +2
Query: 248 RVRRGSSLELKCESYGVPRPHVVWRFNWGCLKDNLRMPVTTQIENCNKVISTLRIINFQP 427
+V G +L+L C G V W G L PV Q S LR+ P
Sbjct: 2351 QVAEGQTLDLNCVVPGQSHAQVTWHKRGGSL------PVRHQTHG-----SLLRLYQASP 2399
Query: 428 GDDGIYNCESL 460
D G Y C L
Sbjct: 2400 ADSGEYVCRVL 2410
>sp|Q05793|PGBM_MOUSE Basement membrane-specific heparan sulfate proteoglycan core
protein precursor (HSPG) (Perlecan) (PLC)
Length = 3707
Score = 100 bits (248), Expect = 4e-21
Identities = 49/154 (31%), Positives = 81/154 (52%), Gaps = 3/154 (1%)
Frame = +2
Query: 29 WKCDGENDCGNNFDESRCT--ETDNMCNNVKFNC-KDGKVIPRAYQCDKEADCVNGDDEI 199
W+CDG+ DC + DE+ C+ + +C F C + IP ++ CD+E+DC + DE
Sbjct: 342 WRCDGDFDCEDRTDEANCSVKQPGEVCGPTHFQCVSTNRCIPASFHCDEESDCPDRSDEF 401
Query: 200 GCVLPQVTSTTSDKVKRVRRGSSLELKCESYGVPRPHVVWRFNWGCLKDNLRMPVTTQIE 379
GC+ PQV + + + RG ++ C + GVP P + WR NWG + + R+ +T++
Sbjct: 402 GCMPPQVVTPPQQSI-QASRGQTVTFTCVATGVPTPIINWRLNWGHIPAHPRVTMTSEGG 460
Query: 380 NCNKVISTLRIINFQPGDDGIYNCESLSGPNRSF 481
TL I + + D G Y CE+++ F
Sbjct: 461 R-----GTLIIRDVKEADQGAYTCEAMNSRGMVF 489
Score = 43.9 bits (102), Expect = 3e-04
Identities = 17/38 (44%), Positives = 22/38 (57%)
Frame = +2
Query: 101 CNNVKFNCKDGKVIPRAYQCDKEADCVNGDDEIGCVLP 214
C + +C G IPR Y CD + DC +G DE+GC P
Sbjct: 285 CGPQEASCHSGHCIPRDYLCDGQEDCRDGSDELGCASP 322
Score = 35.8 bits (81), Expect = 0.088
Identities = 24/80 (30%), Positives = 40/80 (50%), Gaps = 2/80 (2%)
Frame = +2
Query: 80 CTETDNMCNNVKFNCKDGKVIPRAYQCDKEADCVNGDDEIGC--VLPQVTSTTSDKVKRV 253
CTET+ C++ + + Y+CD+ DC + DE+ C +P+++S+T V
Sbjct: 199 CTETEFACHSYN------ECVALEYRCDRRPDCRDMSDELNCEEPVPELSSST----PAV 248
Query: 254 RRGSSLELKCESYGVPRPHV 313
+ S L L E+ P P V
Sbjct: 249 GKVSPLPLWPEAATTPPPPV 268
Score = 33.5 bits (75), Expect = 0.43
Identities = 25/98 (25%), Positives = 38/98 (38%)
Frame = +2
Query: 209 LPQVTSTTSDKVKRVRRGSSLELKCESYGVPRPHVVWRFNWGCLKDNLRMPVTTQIENCN 388
LP V V V G S+E +C + G P+P V W G L+ + T
Sbjct: 2807 LPSVLINVRTSVHSVVVGHSVEFECLALGDPKPQVTWSKVGGHLRPGIVQSGT------- 2859
Query: 389 KVISTLRIINFQPGDDGIYNCESLSGPNRSFSEDYQLI 502
+RI + + D G Y C + + + S L+
Sbjct: 2860 ----IIRIAHVELADAGQYRCAATNAAGTTQSHVLLLV 2893
Score = 33.1 bits (74), Expect = 0.57
Identities = 21/71 (29%), Positives = 31/71 (43%)
Frame = +2
Query: 251 VRRGSSLELKCESYGVPRPHVVWRFNWGCLKDNLRMPVTTQIENCNKVISTLRIINFQPG 430
V+ G E +C + G P P + W + ++P QI N LR+ +P
Sbjct: 1876 VQPGQQAEFRCSATGNPTPMLEWIGG-----PSGQLPAKAQIHN-----GILRLPAIEPS 1925
Query: 431 DDGIYNCESLS 463
D G Y C +LS
Sbjct: 1926 DQGQYLCRALS 1936
Score = 32.3 bits (72), Expect = 0.97
Identities = 24/83 (28%), Positives = 32/83 (38%)
Frame = +2
Query: 206 VLPQVTSTTSDKVKRVRRGSSLELKCESYGVPRPHVVWRFNWGCLKDNLRMPVTTQIENC 385
V+P + TS RV G +L+L C G V W G L P Q+
Sbjct: 2147 VVPPIRIETSSS--RVAEGQTLDLSCVVPGQAHAQVTWHKRGGSL------PAGHQVHG- 2197
Query: 386 NKVISTLRIINFQPGDDGIYNCE 454
LR+ P D G Y+C+
Sbjct: 2198 ----HMLRLNRVSPADSGEYSCQ 2216
Score = 30.0 bits (66), Expect = 4.8
Identities = 19/70 (27%), Positives = 29/70 (41%)
Frame = +2
Query: 248 RVRRGSSLELKCESYGVPRPHVVWRFNWGCLKDNLRMPVTTQIENCNKVISTLRIINFQP 427
+V G ++ L C + GVP + WR K+ +P Q S LR+ +
Sbjct: 1965 QVHEGRTVRLYCRAAGVPSASITWR------KEGGSLPFRHQAHG-----SRLRLHHMSV 2013
Query: 428 GDDGIYNCES 457
D G Y C +
Sbjct: 2014 ADSGEYVCRA 2023
Score = 29.6 bits (65), Expect = 6.3
Identities = 25/101 (24%), Positives = 42/101 (41%), Gaps = 2/101 (1%)
Frame = +2
Query: 212 PQVTSTTSDKVKRVRRGSSLELKCESYGVPRPHVVWRFNWGCLKDNLRMPVTTQIENCNK 391
P S + V+ G + L+C S G PR W L +PV +
Sbjct: 2433 PPTVSVLPEGPVHVKMGKDITLECISSGEPRSSPRWT--------RLGIPVKLEPRMFGL 2484
Query: 392 VIS--TLRIINFQPGDDGIYNCESLSGPNRSFSEDYQLILD 508
+ S L+I + +P D G Y C++ + + + +LI+D
Sbjct: 2485 MNSHAMLKIASVKPSDAGTYVCQAQNALGTA-QKQVELIVD 2524
Score = 29.6 bits (65), Expect = 6.3
Identities = 22/81 (27%), Positives = 37/81 (45%)
Frame = +2
Query: 209 LPQVTSTTSDKVKRVRRGSSLELKCESYGVPRPHVVWRFNWGCLKDNLRMPVTTQIENCN 388
LPQ+++ RV GS+ C + G P P + W K + +P +++EN
Sbjct: 2896 LPQISTPPEI---RVPAGSAAVFPCMASGYPTPAITWS------KVDGDLPPDSRLEN-- 2944
Query: 389 KVISTLRIINFQPGDDGIYNC 451
+ L + + +P D G Y C
Sbjct: 2945 ---NMLMLPSVRPEDAGTYVC 2962
>sp|P98164|LRP2_HUMAN Low-density lipoprotein receptor-related protein 2 precursor
(Megalin) (Glycoprotein 330) (gp330)
Length = 4655
Score = 70.9 bits (172), Expect = 2e-12
Identities = 28/62 (45%), Positives = 40/62 (64%)
Frame = +2
Query: 26 HWKCDGENDCGNNFDESRCTETDNMCNNVKFNCKDGKVIPRAYQCDKEADCVNGDDEIGC 205
+W CD +NDCG+ DE C T+ C +FNC + + I ++ CD + DCV+G DE+GC
Sbjct: 1125 NWVCDTDNDCGDGSDEKNCNSTET-CQPSQFNCPNHRCIDLSFVCDGDKDCVDGSDEVGC 1183
Query: 206 VL 211
VL
Sbjct: 1184 VL 1185
Score = 66.2 bits (160), Expect = 6e-11
Identities = 26/68 (38%), Positives = 38/68 (55%)
Frame = +2
Query: 29 WKCDGENDCGNNFDESRCTETDNMCNNVKFNCKDGKVIPRAYQCDKEADCVNGDDEIGCV 208
WKCD +NDCG+ DE + C+ F C +G+ + +Y+CD DC +G DE GC+
Sbjct: 2717 WKCDNDNDCGDGSDEMESVCALHTCSPTAFTCANGRCVQYSYRCDYYNDCGDGSDEAGCL 2776
Query: 209 LPQVTSTT 232
+TT
Sbjct: 2777 FRDCNATT 2784
Score = 65.5 bits (158), Expect = 1e-10
Identities = 26/60 (43%), Positives = 37/60 (61%)
Frame = +2
Query: 26 HWKCDGENDCGNNFDESRCTETDNMCNNVKFNCKDGKVIPRAYQCDKEADCVNGDDEIGC 205
++ CDG +DC +N DE C +N C++ F C G+ IP ++CDK DCV+G DE C
Sbjct: 1042 YYLCDGVDDCHDNSDEQLCGTLNNTCSSSAFTCGHGECIPAHWRCDKRNDCVDGSDEHNC 1101
Score = 62.8 bits (151), Expect = 7e-10
Identities = 24/54 (44%), Positives = 36/54 (66%)
Frame = +2
Query: 35 CDGENDCGNNFDESRCTETDNMCNNVKFNCKDGKVIPRAYQCDKEADCVNGDDE 196
CDG+NDCG+N DE+ T + C++ +F C G+ IP+ + CD+E DC + DE
Sbjct: 2842 CDGDNDCGDNSDENPTYCTTHTCSSSEFQCASGRCIPQHWYCDQETDCFDASDE 2895
Score = 62.0 bits (149), Expect = 1e-09
Identities = 28/61 (45%), Positives = 39/61 (63%)
Frame = +2
Query: 32 KCDGENDCGNNFDESRCTETDNMCNNVKFNCKDGKVIPRAYQCDKEADCVNGDDEIGCVL 211
KCD + DC ++ DE CTE +C + +F+C +G+ IPRAY CD + DC +G DE C
Sbjct: 163 KCDWKVDCRDSSDEINCTE---ICLHNEFSCGNGECIPRAYVCDHDNDCQDGSDEHACNY 219
Query: 212 P 214
P
Sbjct: 220 P 220
Score = 59.3 bits (142), Expect = 7e-09
Identities = 24/61 (39%), Positives = 34/61 (55%)
Frame = +2
Query: 23 VHWKCDGENDCGNNFDESRCTETDNMCNNVKFNCKDGKVIPRAYQCDKEADCVNGDDEIG 202
+ W+CDG+NDCG+N DE C + C +F C + + IP + CD DC + DE
Sbjct: 3735 LRWQCDGQNDCGDNSDEENCApre--CTESEFRCVNQQCIPSRWICDHYNDCGDNSDERD 3792
Query: 203 C 205
C
Sbjct: 3793 C 3793
Score = 56.6 bits (135), Expect = 5e-08
Identities = 26/64 (40%), Positives = 38/64 (59%), Gaps = 2/64 (3%)
Frame = +2
Query: 32 KCDGENDCGNNFDESRC-TETDNMCNNVKFNCK-DGKVIPRAYQCDKEADCVNGDDEIGC 205
+CDG DC +N DE+ C T MC++ +F C+ DG IP ++CD DC+ G DE
Sbjct: 1206 RCDGVFDCSDNSDEAGCPTRPPGMCHSDEFQCQEDGICIPNFWECDGHPDCLYGSDEHNA 1265
Query: 206 VLPQ 217
+P+
Sbjct: 1266 CVPK 1269
Score = 55.8 bits (133), Expect = 8e-08
Identities = 24/61 (39%), Positives = 37/61 (60%), Gaps = 1/61 (1%)
Frame = +2
Query: 29 WKCDGENDCGNNFDESR-CTETDNMCNNVKFNCKDGKVIPRAYQCDKEADCVNGDDEIGC 205
W CDG+ DC + +DE++ CT C+ +F C G IP+ ++CD+ DC + DE GC
Sbjct: 2970 WVCDGDVDCTDGYDENQNCTR--RTCSENEFTCGYGLCIPKIFRCDRHNDCGDYSDERGC 3027
Query: 206 V 208
+
Sbjct: 3028 L 3028
Score = 55.5 bits (132), Expect = 1e-07
Identities = 25/71 (35%), Positives = 38/71 (53%), Gaps = 1/71 (1%)
Frame = +2
Query: 29 WKCDGENDCGNNFDESR-CTETDNMCNNVKFNCKDGKVIPRAYQCDKEADCVNGDDEIGC 205
W CD + DC + DE + C+++ C++ + C +G+ IP Y+CD DC +G DE C
Sbjct: 85 WVCDQDQDCDDGSDERQDCSQST--CSSHQITCSNGQCIPSEYRCDHVRDCPDGADENDC 142
Query: 206 VLPQVTSTTSD 238
P T D
Sbjct: 143 QYPTCEQLTCD 153
Score = 54.7 bits (130), Expect = 2e-07
Identities = 22/61 (36%), Positives = 33/61 (54%), Gaps = 1/61 (1%)
Frame = +2
Query: 26 HWKCDGENDCGNNFDESRC-TETDNMCNNVKFNCKDGKVIPRAYQCDKEADCVNGDDEIG 202
HW+CD NDC + DE C T C + ++ C + + I + + CD + DC +G DE
Sbjct: 1083 HWRCDKRNDCVDGSDEHNCPTHAPASCLDTQYTCDNHQCISKNWVCDTDNDCGDGSDEKN 1142
Query: 203 C 205
C
Sbjct: 1143 C 1143
Score = 54.3 bits (129), Expect = 2e-07
Identities = 22/56 (39%), Positives = 32/56 (57%)
Frame = +2
Query: 29 WKCDGENDCGNNFDESRCTETDNMCNNVKFNCKDGKVIPRAYQCDKEADCVNGDDE 196
W+CD NDC +N DE C +F C +G+ IP+A++CD + DC + DE
Sbjct: 3611 WQCDTFNDCEDNSDEDSSHCASRTCRPGQFRCANGRCIPQAWKCDVDNDCGDHSDE 3666
Score = 53.1 bits (126), Expect = 5e-07
Identities = 24/62 (38%), Positives = 37/62 (59%), Gaps = 6/62 (9%)
Frame = +2
Query: 29 WKCDGENDCGNNFDESRCTETDNM-CNNVKFNC-----KDGKVIPRAYQCDKEADCVNGD 190
W CDG+NDCG+ DE + + N C++ +F C D + IP+++ CD + DC +G
Sbjct: 2923 WICDGDNDCGDMSDEDKRHQCQNQNCSDSEFLCVNDRPPDRRCIPQSWVCDGDVDCTDGY 2982
Query: 191 DE 196
DE
Sbjct: 2983 DE 2984
Score = 53.1 bits (126), Expect = 5e-07
Identities = 24/67 (35%), Positives = 38/67 (56%), Gaps = 2/67 (2%)
Frame = +2
Query: 29 WKCDGENDCGNNFDESRCTETDNMCNNVKFNCKDGKVIPRAYQCDKEADCVNGDDEIG-- 202
++CD NDCG+ DE C C +F C++G+ I + + CD++ DC +G DE+
Sbjct: 3010 FRCDRHNDCGDYSDERGCLY--QTCQQNQFTCQNGRCISKTFVCDEDNDCGDGSDELMHL 3067
Query: 203 CVLPQVT 223
C P+ T
Sbjct: 3068 CHTPEPT 3074
Score = 52.8 bits (125), Expect = 7e-07
Identities = 25/63 (39%), Positives = 38/63 (60%), Gaps = 4/63 (6%)
Frame = +2
Query: 29 WKCDGENDCGNNFDE--SRCTETDNMCNN-VKFNCKDG-KVIPRAYQCDKEADCVNGDDE 196
WKCD +NDCG++ DE C + ++C+N +F+CK + IP+ C+ DC + DE
Sbjct: 3652 WKCDVDNDCGDHSDEPIEECMSSAHLCDNFTEFSCKTNYRCIPKWAVCNGVDDCRDNSDE 3711
Query: 197 IGC 205
GC
Sbjct: 3712 QGC 3714
Score = 52.4 bits (124), Expect = 9e-07
Identities = 23/59 (38%), Positives = 29/59 (49%)
Frame = +2
Query: 29 WKCDGENDCGNNFDESRCTETDNMCNNVKFNCKDGKVIPRAYQCDKEADCVNGDDEIGC 205
W CD NDCG+N DE C C+ F C G + +CD ADC++ DE C
Sbjct: 3776 WICDHYNDCGDNSDERDCEM--RTCHPEYFQCTSGHCVHSELKCDGSADCLDASDEADC 3832
Score = 51.6 bits (122), Expect = 2e-06
Identities = 22/57 (38%), Positives = 33/57 (57%), Gaps = 1/57 (1%)
Frame = +2
Query: 29 WKCDGENDCGNNFDESRCTETDNMCNNVKFNCK-DGKVIPRAYQCDKEADCVNGDDE 196
W+CDG DC ++ DE C C F C+ +G+ IP ++ CD++ DC +G DE
Sbjct: 45 WRCDGTKDCSDDADEIGCAVVT--CQQGYFKCQSEGQCIPSSWVCDQDQDCDDGSDE 99
Score = 49.7 bits (117), Expect = 6e-06
Identities = 25/66 (37%), Positives = 35/66 (53%), Gaps = 1/66 (1%)
Frame = +2
Query: 35 CDGENDCGNNFDESRCTETDNMCNNV-KFNCKDGKVIPRAYQCDKEADCVNGDDEIGCVL 211
C+G +DC +N DE C E C+ V F CK+ IP +QCD + DC + DE C
Sbjct: 3699 CNGVDDCRDNSDEQGCEE--RTCHPVGDFRCKNHHCIPLRWQCDGQNDCGDNSDEENCAP 3756
Query: 212 PQVTST 229
+ T +
Sbjct: 3757 RECTES 3762
Score = 49.3 bits (116), Expect = 8e-06
Identities = 22/57 (38%), Positives = 29/57 (50%)
Frame = +2
Query: 35 CDGENDCGNNFDESRCTETDNMCNNVKFNCKDGKVIPRAYQCDKEADCVNGDDEIGC 205
CD +NDC + DE C C +F C G+ I + + CD E DC + DE GC
Sbjct: 202 CDHDNDCQDGSDEHACNYPT--CGGYQFTCPSGRCIYQNWVCDGEDDCKDNGDEDGC 256
Score = 49.3 bits (116), Expect = 8e-06
Identities = 22/58 (37%), Positives = 31/58 (53%), Gaps = 1/58 (1%)
Frame = +2
Query: 26 HWKCDGENDCGNNFDE-SRCTETDNMCNNVKFNCKDGKVIPRAYQCDKEADCVNGDDE 196
HW CD E DC + DE + C ++ C +F C G+ IP + CD + DC + DE
Sbjct: 2880 HWYCDQETDCFDASDEPASCGHSERTCLADEFKCDGGRCIPSEWICDGDNDCGDMSDE 2937
Score = 48.9 bits (115), Expect = 1e-05
Identities = 23/63 (36%), Positives = 33/63 (52%), Gaps = 3/63 (4%)
Frame = +2
Query: 26 HWKCDGENDCGNNFDESR--CTE-TDNMCNNVKFNCKDGKVIPRAYQCDKEADCVNGDDE 196
H C+G +DCG+ DE+ C + T C ++ C +G IP CD DC + DE
Sbjct: 3900 HEVCNGVDDCGDGTDETEEHCRKPTPKPCTEYEYKCGNGHCIPHDNVCDDADDCGDWSDE 3959
Query: 197 IGC 205
+GC
Sbjct: 3960 LGC 3962
Score = 47.8 bits (112), Expect = 2e-05
Identities = 22/59 (37%), Positives = 30/59 (50%)
Frame = +2
Query: 29 WKCDGENDCGNNFDESRCTETDNMCNNVKFNCKDGKVIPRAYQCDKEADCVNGDDEIGC 205
W+CDG DC DE C + F+C +G I RA+ CD++ DC + DE C
Sbjct: 1248 WECDGHPDCLYGSDEHNAC-VPKTCPSSYFHCDNGNCIHRAWLCDRDNDCGDMSDEKDC 1305
Score = 47.0 bits (110), Expect = 4e-05
Identities = 22/58 (37%), Positives = 32/58 (55%), Gaps = 1/58 (1%)
Frame = +2
Query: 26 HWKCDGENDCGNNFDESRCTETDNMCNNV-KFNCKDGKVIPRAYQCDKEADCVNGDDE 196
+WKCDG++DCG+ DE D CN+ +F C + + I C+ DC +G DE
Sbjct: 3858 YWKCDGDDDCGDGSDEELHLCLDVPCNSPNRFRCDNNRCIYSHEVCNGVDDCGDGTDE 3915
Score = 45.4 bits (106), Expect = 1e-04
Identities = 21/59 (35%), Positives = 30/59 (50%), Gaps = 2/59 (3%)
Frame = +2
Query: 35 CDGENDCGNNFDESR--CTETDNMCNNVKFNCKDGKVIPRAYQCDKEADCVNGDDEIGC 205
CD +NDCG+ DE C + C +F C +G+ I C+ DC++ DE GC
Sbjct: 3051 CDEDNDCGDGSDELMHLCHTPEPTCPPHEFKCDNGRCIEMMKLCNHLDDCLDNSDEKGC 3109
Score = 45.1 bits (105), Expect = 1e-04
Identities = 22/58 (37%), Positives = 29/58 (50%), Gaps = 3/58 (5%)
Frame = +2
Query: 32 KCDGENDCGNNFDESRCTET---DNMCNNVKFNCKDGKVIPRAYQCDKEADCVNGDDE 196
KCDG DC + DE+ C C F CK+ IP ++CD + DC +G DE
Sbjct: 3816 KCDGSADCLDASDEADCPTRFPDGAYCQATMFECKNHVCIPPYWKCDGDDDCGDGSDE 3873
Score = 44.7 bits (104), Expect = 2e-04
Identities = 20/59 (33%), Positives = 29/59 (49%), Gaps = 1/59 (1%)
Frame = +2
Query: 23 VHWKCDGENDCGNNFDE-SRCTETDNMCNNVKFNCKDGKVIPRAYQCDKEADCVNGDDE 196
+ WKCDG+ DC + DE + C + C +F C DG C+ +C +G DE
Sbjct: 3528 IWWKCDGQKDCSDGSDELALCPQ--RFCRLGQFQCSDGNCTSPQTLCNAHQNCPDGSDE 3584
Score = 43.1 bits (100), Expect = 5e-04
Identities = 20/57 (35%), Positives = 28/57 (49%), Gaps = 1/57 (1%)
Frame = +2
Query: 29 WKCDGENDCGNNFDESRCTETDNMCNNVKFNCKDGKV-IPRAYQCDKEADCVNGDDE 196
W CD +NDCG+ DE C C + ++ C + + + CD DC NG DE
Sbjct: 1288 WLCDRDNDCGDMSDEKDCPTQPFRCPSWQWQCLGHNICVNLSVVCDGIFDCPNGTDE 1344
Score = 42.4 bits (98), Expect = 0.001
Identities = 23/62 (37%), Positives = 33/62 (53%), Gaps = 3/62 (4%)
Frame = +2
Query: 29 WKCDGENDCGNNFDESRCTETDNMCN-NVKFNCKDGKVIPRAYQCDKEADC--VNGDDEI 199
++CD NDCG+ DE+ C D CN +F C + + IPR + C+ +C N DE
Sbjct: 2758 YRCDYYNDCGDGSDEAGCLFRD--CNATTEFMCNNRRCIpreFICNGVDNCHDNNTSDEK 2815
Query: 200 GC 205
C
Sbjct: 2816 NC 2817
Score = 42.0 bits (97), Expect = 0.001
Identities = 16/54 (29%), Positives = 30/54 (55%)
Frame = +2
Query: 35 CDGENDCGNNFDESRCTETDNMCNNVKFNCKDGKVIPRAYQCDKEADCVNGDDE 196
C+ +C + DE R ++ C++ ++ C + + IP ++QCD DC + DE
Sbjct: 3572 CNAHQNCPDGSDEDRLLCENHHCDSNEWQCANKRCIPESWQCDTFNDCEDNSDE 3625
Score = 40.8 bits (94), Expect = 0.003
Identities = 21/61 (34%), Positives = 32/61 (52%), Gaps = 4/61 (6%)
Frame = +2
Query: 26 HWKCDGENDCGNNFDESRCTETD---NMCNNVKFNC-KDGKVIPRAYQCDKEADCVNGDD 193
+W CDGE+DC +N DE C + C+ +++C + G+ I CD DC +D
Sbjct: 238 NWVCDGEDDCKDNGDEDGCESGPHDVHKCSpreWSCPESGRCISIYKVCDGILDCPGRED 297
Query: 194 E 196
E
Sbjct: 298 E 298
Score = 39.7 bits (91), Expect = 0.006
Identities = 15/37 (40%), Positives = 21/37 (56%)
Frame = +2
Query: 101 CNNVKFNCKDGKVIPRAYQCDKEADCVNGDDEIGCVL 211
C++ F C G IP ++CD DC + DEIGC +
Sbjct: 28 CDSAHFRCGSGHCIPADWRCDGTKDCSDDADEIGCAV 64
Score = 37.4 bits (85), Expect = 0.030
Identities = 18/59 (30%), Positives = 28/59 (47%)
Frame = +2
Query: 29 WKCDGENDCGNNFDESRCTETDNMCNNVKFNCKDGKVIPRAYQCDKEADCVNGDDEIGC 205
++CD DC + DE+ C C + C +G + +CD + DC + DEI C
Sbjct: 125 YRCDHVRDCPDGADENDCQYPT--CEQL--TCDNGACYNTSQKCDWKVDCRDSSDEINC 179
Score = 35.4 bits (80), Expect = 0.11
Identities = 13/36 (36%), Positives = 20/36 (55%)
Frame = +2
Query: 101 CNNVKFNCKDGKVIPRAYQCDKEADCVNGDDEIGCV 208
C F C +G+ I ++CD + DC +G DE+ V
Sbjct: 2700 CGASSFTCSNGRCISEEWKCDNDNDCGDGSDEMESV 2735
Score = 35.0 bits (79), Expect = 0.15
Identities = 14/35 (40%), Positives = 18/35 (51%)
Frame = +2
Query: 101 CNNVKFNCKDGKVIPRAYQCDKEADCVNGDDEIGC 205
C F CK+G+ +P Y CD DC + DE C
Sbjct: 1026 CGLFSFPCKNGRCVPNYYLCDGVDDCHDNSDEQLC 1060
Score = 33.9 bits (76), Expect = 0.33
Identities = 14/35 (40%), Positives = 23/35 (65%), Gaps = 1/35 (2%)
Frame = +2
Query: 98 MCNNVKFNCKDG-KVIPRAYQCDKEADCVNGDDEI 199
MC++ +F C + K IP ++CD + DC +G DE+
Sbjct: 3511 MCSSTQFLCANNEKCIPIWWKCDGQKDCSDGSDEL 3545
>sp|P98157|LRP1_CHICK Low-density lipoprotein receptor-related protein 1 precursor (LRP)
(Alpha-2-macroglobulin receptor) (A2MR)
Length = 4543
Score = 70.5 bits (171), Expect = 3e-12
Identities = 29/65 (44%), Positives = 41/65 (63%), Gaps = 4/65 (6%)
Frame = +2
Query: 29 WKCDGENDCGNNFDES----RCTETDNMCNNVKFNCKDGKVIPRAYQCDKEADCVNGDDE 196
W+CDGE DC ++ DE+ RC+ ++ CN+ F CK+GK IP A CD DC +G DE
Sbjct: 2874 WECDGEFDCHDHSDEAPKNPRCSSPESKCNDSFFMCKNGKCIPEALLCDNNNDCADGSDE 2933
Query: 197 IGCVL 211
+ C +
Sbjct: 2934 LNCFI 2938
Score = 64.7 bits (156), Expect = 2e-10
Identities = 28/63 (44%), Positives = 38/63 (60%), Gaps = 1/63 (1%)
Frame = +2
Query: 29 WKCDGENDCGNNFDESRCTETDNMCNNVKFNCKDGKVIPRAYQCDKEADCVNGDDE-IGC 205
W CDG+NDCGNN DES T + C+ +F+C G+ IP ++ CD + DC + DE C
Sbjct: 910 WLCDGDNDCGNNEDESNSTCSARTCSPNQFSCASGRCIPISWTCDLDDDCGDRSDESASC 969
Query: 206 VLP 214
P
Sbjct: 970 AYP 972
Score = 64.3 bits (155), Expect = 2e-10
Identities = 25/60 (41%), Positives = 38/60 (63%)
Frame = +2
Query: 29 WKCDGENDCGNNFDESRCTETDNMCNNVKFNCKDGKVIPRAYQCDKEADCVNGDDEIGCV 208
W+CD +NDCG+N DE CT C+ +F+C +G+ I ++CD + DC +G DE C+
Sbjct: 3550 WQCDYDNDCGDNSDEESCTPRP--CSESEFSCANGRCIAGRWKCDGDHDCADGSDEKDCI 3607
Score = 63.2 bits (152), Expect = 5e-10
Identities = 24/59 (40%), Positives = 35/59 (59%)
Frame = +2
Query: 29 WKCDGENDCGNNFDESRCTETDNMCNNVKFNCKDGKVIPRAYQCDKEADCVNGDDEIGC 205
WKCDGE+DCG+ DE + + C +F CK+ + +P +QCD + DC + DE C
Sbjct: 3509 WKCDGEDDCGDGSDEPKEECDERTCEPYQFRCKNNRCVPGRWQCDYDNDCGDNSDEESC 3567
Score = 62.8 bits (151), Expect = 7e-10
Identities = 26/63 (41%), Positives = 40/63 (63%), Gaps = 2/63 (3%)
Frame = +2
Query: 23 VHWKCDGENDCGNNFDESRCTETDNMCN-NVKFNCKD-GKVIPRAYQCDKEADCVNGDDE 196
+ W+CDG+ DC ++ DE C ++C+ NVKF CKD + I +A+ CD ++DC + DE
Sbjct: 1076 MRWRCDGDTDCMDSSDEKNCEGVTHVCDPNVKFGCKDSARCISKAWVCDGDSDCEDNSDE 1135
Query: 197 IGC 205
C
Sbjct: 1136 ENC 1138
Score = 62.8 bits (151), Expect = 7e-10
Identities = 25/59 (42%), Positives = 36/59 (61%)
Frame = +2
Query: 29 WKCDGENDCGNNFDESRCTETDNMCNNVKFNCKDGKVIPRAYQCDKEADCVNGDDEIGC 205
WKCDG++DC + DE C C ++ CK+G IP ++CD +ADC++G DE C
Sbjct: 3589 WKCDGDHDCADGSDEKDCIPR---CEFDQYQCKNGHCIPMRWRCDADADCMDGTDEEDC 3644
Score = 62.0 bits (149), Expect = 1e-09
Identities = 28/60 (46%), Positives = 32/60 (53%), Gaps = 1/60 (1%)
Frame = +2
Query: 29 WKCDGENDCGNNFDESRCTETDN-MCNNVKFNCKDGKVIPRAYQCDKEADCVNGDDEIGC 205
W CDG NDCG+ DE C C F C G+ IP + CDKE DC NG+DE C
Sbjct: 2665 WVCDGANDCGDYSDERNCPGGRKPKCPANYFACPSGRCIPMTWTCDKEDDCENGEDETHC 2724
Score = 61.6 bits (148), Expect = 1e-09
Identities = 27/68 (39%), Positives = 39/68 (57%), Gaps = 7/68 (10%)
Frame = +2
Query: 23 VHWKCDGENDCGNNFDE------SRCTETDNMCNNVKFNCK-DGKVIPRAYQCDKEADCV 181
VHW CDG+NDCG+ DE ++ T C+ +F C+ DG IP ++CD + DC+
Sbjct: 1028 VHWTCDGDNDCGDYSDETHANCTNQATRPPGGCHTDEFQCRLDGLCIPMRWRCDGDTDCM 1087
Query: 182 NGDDEIGC 205
+ DE C
Sbjct: 1088 DSSDEKNC 1095
Score = 60.5 bits (145), Expect = 3e-09
Identities = 23/58 (39%), Positives = 38/58 (65%)
Frame = +2
Query: 23 VHWKCDGENDCGNNFDESRCTETDNMCNNVKFNCKDGKVIPRAYQCDKEADCVNGDDE 196
++W+CD +NDCG+N DE+ C+ + C++ +F C G+ IP + CD + DC + DE
Sbjct: 990 INWRCDNDNDCGDNSDEAGCSHS---CSSNQFKCNSGRCIPVHWTCDGDNDCGDYSDE 1044
Score = 59.7 bits (143), Expect = 6e-09
Identities = 24/56 (42%), Positives = 35/56 (62%)
Frame = +2
Query: 29 WKCDGENDCGNNFDESRCTETDNMCNNVKFNCKDGKVIPRAYQCDKEADCVNGDDE 196
WKCDG+NDC +N DE+ + C + +F CK+ + IP + CD + DC N +DE
Sbjct: 869 WKCDGDNDCLDNSDEAPELCHQHTCPSDRFKCKNNRCIPNRWLCDGDNDCGNNEDE 924
Score = 56.2 bits (134), Expect = 6e-08
Identities = 24/57 (42%), Positives = 33/57 (57%), Gaps = 1/57 (1%)
Frame = +2
Query: 29 WKCDGENDCGNNFDESRCTET-DNMCNNVKFNCKDGKVIPRAYQCDKEADCVNGDDE 196
W CD E+DC N DE+ C+E D C V+F C + + I + + CD DC +G DE
Sbjct: 2707 WTCDKEDDCENGEDETHCSERQDKFCYPVQFECNNHRCISKLWVCDGADDCGDGSDE 2763
Score = 55.1 bits (131), Expect = 1e-07
Identities = 29/84 (34%), Positives = 45/84 (53%)
Frame = +2
Query: 35 CDGENDCGNNFDESRCTETDNMCNNVKFNCKDGKVIPRAYQCDKEADCVNGDDEIGCVLP 214
C+G +DCG+N DE C +T C +F C+DG I + +C++ DC + DE+ C
Sbjct: 2579 CNGVDDCGDNSDEVPCNKTS--CAATEFRCRDGSCIGNSSRCNQFIDCEDASDEMNCTAT 2636
Query: 215 QVTSTTSDKVKRVRRGSSLELKCE 286
+S VK G++ + KCE
Sbjct: 2637 DCSSYFKLGVK----GTTFQ-KCE 2655
Score = 52.8 bits (125), Expect = 7e-07
Identities = 26/58 (44%), Positives = 35/58 (60%), Gaps = 2/58 (3%)
Frame = +2
Query: 29 WKCDGENDCGNNFDE-SRCTETDNMCNNVKFNCKD-GKVIPRAYQCDKEADCVNGDDE 196
W CD +NDC + DE + CT+ C +F CKD G+ IP ++CD E DC +G DE
Sbjct: 3468 WVCDRDNDCVDGSDEPANCTQMT--CGVDEFRCKDSGRCIPARWKCDGEDDCGDGSDE 3523
Score = 52.0 bits (123), Expect = 1e-06
Identities = 21/61 (34%), Positives = 32/61 (52%)
Frame = +2
Query: 23 VHWKCDGENDCGNNFDESRCTETDNMCNNVKFNCKDGKVIPRAYQCDKEADCVNGDDEIG 202
+ W CD ++DCG+ DES +F C +G+ I ++CD + DC + DE G
Sbjct: 949 ISWTCDLDDDCGDRSDESASCAYPTCFPLTQFTCNNGRCININWRCDNDNDCGDNSDEAG 1008
Query: 203 C 205
C
Sbjct: 1009 C 1009
Score = 50.8 bits (120), Expect = 3e-06
Identities = 21/58 (36%), Positives = 33/58 (56%), Gaps = 2/58 (3%)
Frame = +2
Query: 29 WKCDGENDCGNNFDESRCTET--DNMCNNVKFNCKDGKVIPRAYQCDKEADCVNGDDE 196
W CDG+ DC + DE+ +N C+ +F C + + IP+ + CD + DC +G DE
Sbjct: 2790 WLCDGDKDCADGADETLAAGCLYNNTCDEREFMCGNRQCIPKHFVCDHDDDCGDGSDE 2847
Score = 50.8 bits (120), Expect = 3e-06
Identities = 37/136 (27%), Positives = 67/136 (49%), Gaps = 1/136 (0%)
Frame = +2
Query: 35 CDGENDCGNNFDESRCTETDNMCNNVKFNCKD-GKVIPRAYQCDKEADCVNGDDEIGCVL 211
CDG+NDC +N DE+ C ++C +F C + + IP ++C+ + +C +G+DE C
Sbjct: 3390 CDGDNDCQDNSDEANC--DIHVCLPSQFKCTNTNRCIPGIFRCNGQDNCGDGEDEKDC-- 3445
Query: 212 PQVTSTTSDKVKRVRRGSSLELKCESYGVPRPHVVWRFNWGCLKDNLRMPVTTQIENCNK 391
P+VT + + ++ +C +PR W C +DN + + + NC +
Sbjct: 3446 PEVTCAPN------QFQCAITKRC----IPRV-------WVCDRDNDCVDGSDEPANCTQ 3488
Query: 392 VISTLRIINFQPGDDG 439
+ T + F+ D G
Sbjct: 3489 M--TCGVDEFRCKDSG 3502
Score = 50.1 bits (118), Expect = 4e-06
Identities = 23/57 (40%), Positives = 35/57 (61%), Gaps = 1/57 (1%)
Frame = +2
Query: 29 WKCDGENDCGNNFDESRCTETDNMCNNVKFNCKDGK-VIPRAYQCDKEADCVNGDDE 196
++C+G+++CG+ DE C E C +F C K IPR + CD++ DCV+G DE
Sbjct: 3428 FRCNGQDNCGDGEDEKDCPEVT--CAPNQFQCAITKRCIPRVWVCDRDNDCVDGSDE 3482
Score = 49.7 bits (117), Expect = 6e-06
Identities = 27/65 (41%), Positives = 35/65 (53%), Gaps = 5/65 (7%)
Frame = +2
Query: 29 WKCDGENDCGNNFDE-SRCTETDNMCNNVKFNCKDGKV-IPRAYQCDKEADCVNGDDE-- 196
W CDG +DCG+ DE SRC T C+ F C V +P + CD + DC +G DE
Sbjct: 2749 WVCDGADDCGDGSDEDSRCRLTT--CSTGSFQCPGTYVCVPERWLCDGDKDCADGADETL 2806
Query: 197 -IGCV 208
GC+
Sbjct: 2807 AAGCL 2811
Score = 49.3 bits (116), Expect = 8e-06
Identities = 24/60 (40%), Positives = 30/60 (50%), Gaps = 1/60 (1%)
Frame = +2
Query: 29 WKCDGENDCGNNFDESR-CTETDNMCNNVKFNCKDGKVIPRAYQCDKEADCVNGDDEIGC 205
WKCD E+DCG+ DE C E C +F C G A+ CD + DC + DE C
Sbjct: 3348 WKCDTEDDCGDRSDEPEDCPEF--KCRPGQFQCSTGICTNPAFICDGDNDCQDNSDEANC 3405
Score = 46.6 bits (109), Expect = 5e-05
Identities = 20/58 (34%), Positives = 29/58 (50%)
Frame = +2
Query: 23 VHWKCDGENDCGNNFDESRCTETDNMCNNVKFNCKDGKVIPRAYQCDKEADCVNGDDE 196
+ W+CD + DC + DE C C +F C + P A++CD E DC + DE
Sbjct: 3625 MRWRCDADADCMDGTDEEDCGTGVRTCPLDEFQCNNTLRKPLAWKCDGEDDCGDNSDE 3682
Score = 46.2 bits (108), Expect = 6e-05
Identities = 26/64 (40%), Positives = 34/64 (53%), Gaps = 2/64 (3%)
Frame = +2
Query: 29 WKCDGENDCGNNFDESRCTETDNMC-NNVKFNCKDGKV-IPRAYQCDKEADCVNGDDEIG 202
WKCDGE+DCG+N DE+ C N F CK+ +V + QCD +C + DE
Sbjct: 3668 WKCDGEDDCGDNSDENPEECLKFQCPPNRPFRCKNDRVCLWIGRQCDGIDNCGDNTDEKD 3727
Query: 203 CVLP 214
C P
Sbjct: 3728 CESP 3731
Score = 42.7 bits (99), Expect = 7e-04
Identities = 21/58 (36%), Positives = 27/58 (46%), Gaps = 2/58 (3%)
Frame = +2
Query: 29 WKCDGENDCGNNFDESRCTETDNMCNNVKFNCKDGKVI--PRAYQCDKEADCVNGDDE 196
W CDG++DC +N DE C +C C + I P CD DC +G DE
Sbjct: 1121 WVCDGDSDCEDNSDEENCESL--VCKPPSHTCANNTSICLPPEKLCDGSDDCGDGSDE 1176
Score = 42.7 bits (99), Expect = 7e-04
Identities = 23/63 (36%), Positives = 33/63 (52%), Gaps = 5/63 (7%)
Frame = +2
Query: 32 KCDGENDCGNNFDESRC---TETDNMCNNVK--FNCKDGKVIPRAYQCDKEADCVNGDDE 196
+CDG ++CG+N DE C T C+ K F C++ K I +C+ DC +G DE
Sbjct: 3712 QCDGIDNCGDNTDEKDCESPTAKPKSCSQDKNEFLCENKKCISANLRCNFFDDCGDGSDE 3771
Query: 197 IGC 205
C
Sbjct: 3772 KSC 3774
Score = 37.7 bits (86), Expect = 0.023
Identities = 18/49 (36%), Positives = 26/49 (53%), Gaps = 1/49 (2%)
Frame = +2
Query: 74 SRCTETDNMCNNVKFNCKDG-KVIPRAYQCDKEADCVNGDDEIGCVLPQ 217
+R E C+ +F CKD I + ++CD E DC +G DE + PQ
Sbjct: 20 ARALEAPKTCSPKQFACKDQITCISKGWRCDGEKDCPDGSDESPDICPQ 68
Score = 37.7 bits (86), Expect = 0.023
Identities = 21/60 (35%), Positives = 32/60 (53%), Gaps = 4/60 (6%)
Frame = +2
Query: 29 WKCDGENDCGNNFDESR--CTETD-NMCNNVKFNCKDGKV-IPRAYQCDKEADCVNGDDE 196
W+CDGE DC + DES C ++ + C + NC ++ I + C+ DC +G DE
Sbjct: 47 WRCDGEKDCPDGSDESPDICPQSKVSRCQPNEHNCLGTELCIHMSKLCNGLHDCFDGSDE 106
Score = 37.4 bits (85), Expect = 0.030
Identities = 15/57 (26%), Positives = 26/57 (45%)
Frame = +2
Query: 35 CDGENDCGNNFDESRCTETDNMCNNVKFNCKDGKVIPRAYQCDKEADCVNGDDEIGC 205
CDG C + DE + + C +C +G+ + + C+ DC + DE+ C
Sbjct: 2538 CDGVVHCKDKSDEKQSYCSSRKCKKGFLHCMNGRCVASRFWCNGVDDCGDNSDEVPC 2594
Score = 33.9 bits (76), Expect = 0.33
Identities = 19/52 (36%), Positives = 24/52 (46%), Gaps = 4/52 (7%)
Frame = +2
Query: 53 CGNNF----DESRCTETDNMCNNVKFNCKDGKVIPRAYQCDKEADCVNGDDE 196
C NF D C C +F CK+ K IP ++CD E DC + DE
Sbjct: 3314 CPTNFYLGSDGKTCVSN---CTASQFVCKNDKCIPFWWKCDTEDDCGDRSDE 3362
Score = 32.0 bits (71), Expect = 1.3
Identities = 11/32 (34%), Positives = 19/32 (59%)
Frame = +2
Query: 101 CNNVKFNCKDGKVIPRAYQCDKEADCVNGDDE 196
C +F CK+ + I ++CD + DC++ DE
Sbjct: 852 CQPGEFACKNNRCIQERWKCDGDNDCLDNSDE 883
>sp|Q9NZR2|LRP1B_HUMAN Low-density lipoprotein receptor-related protein 1B precursor
(Low-density lipoprotein receptor-related protein-deleted
in tumor) (LRP-DIT)
Length = 4599
Score = 68.9 bits (167), Expect = 9e-12
Identities = 38/88 (43%), Positives = 49/88 (55%), Gaps = 1/88 (1%)
Frame = +2
Query: 29 WKCDGENDCGNNFDESRCTETDNMCNNVKFNCKDGKVIPRAYQCDKEADCVNGDDEI-GC 205
W CDG NDCG+N DES T T C +F+C +G+ IPRA+ CD+E DC + DE+ C
Sbjct: 903 WLCDGANDCGSNEDESNQTCTARTCQVDQFSCGNGRCIPRAWLCDREDDCGDQTDEMASC 962
Query: 206 VLPQVTSTTSDKVKRVRRGSSLELKCES 289
P T K R SS + C+S
Sbjct: 963 EFPTCEPLTQFVCKSGRCISS-KWHCDS 989
Score = 64.7 bits (156), Expect = 2e-10
Identities = 30/67 (44%), Positives = 41/67 (61%), Gaps = 7/67 (10%)
Frame = +2
Query: 26 HWKCDGENDCGNNFDESR--CTETDNM----CNNVKFNCK-DGKVIPRAYQCDKEADCVN 184
HW CDG+NDCG+ DE++ CT+ + CN +F C DG +P ++CD E DC +
Sbjct: 1022 HWACDGDNDCGDFSDEAQINCTKEEIHSPAGCNGNEFQCHPDGNCVPDLWRCDGEKDCED 1081
Query: 185 GDDEIGC 205
G DE GC
Sbjct: 1082 GSDEKGC 1088
Score = 63.5 bits (153), Expect = 4e-10
Identities = 27/57 (47%), Positives = 35/57 (61%)
Frame = +2
Query: 35 CDGENDCGNNFDESRCTETDNMCNNVKFNCKDGKVIPRAYQCDKEADCVNGDDEIGC 205
CDGENDCG+N DE C + C V+F C DG IPR+ +C++ DC + DE C
Sbjct: 2571 CDGENDCGDNSDELDCKVST--CATVEFRCADGTCIPRSARCNQNIDCADASDEKNC 2625
Score = 61.2 bits (147), Expect = 2e-09
Identities = 28/92 (30%), Positives = 47/92 (51%), Gaps = 4/92 (4%)
Frame = +2
Query: 29 WKCDGENDCGNNFDES----RCTETDNMCNNVKFNCKDGKVIPRAYQCDKEADCVNGDDE 196
W+CDG+ DC ++ DE+ +C + CN+ F CK+G+ IP CD + DC +G DE
Sbjct: 2863 WQCDGDFDCPDHSDEAPLNPKCKSAEQSCNSSFFMCKNGRCIPSGGLCDNKDDCGDGSDE 2922
Query: 197 IGCVLPQVTSTTSDKVKRVRRGSSLELKCESY 292
C + + S + + + KC+ +
Sbjct: 2923 RNCHINECLSKKVSGCSQDCQDLPVSYKCKCW 2954
Score = 59.3 bits (142), Expect = 7e-09
Identities = 25/60 (41%), Positives = 33/60 (55%)
Frame = +2
Query: 29 WKCDGENDCGNNFDESRCTETDNMCNNVKFNCKDGKVIPRAYQCDKEADCVNGDDEIGCV 208
W CD E+DCG+ DE E +F CK G+ I + CD + DC +G DE+GCV
Sbjct: 944 WLCDREDDCGDQTDEMASCEFPTCEPLTQFVCKSGRCISSKWHCDSDDDCGDGSDEVGCV 1003
Score = 58.5 bits (140), Expect = 1e-08
Identities = 23/60 (38%), Positives = 31/60 (51%)
Frame = +2
Query: 26 HWKCDGENDCGNNFDESRCTETDNMCNNVKFNCKDGKVIPRAYQCDKEADCVNGDDEIGC 205
HW+CD +NDC +N DE C C F C +G + + CD + DC +G DE C
Sbjct: 3492 HWRCDSQNDCSDNSDEENC--KPQTCTLKDFLCANGDCVSSRFWCDGDFDCADGSDERNC 3549
Score = 57.8 bits (138), Expect = 2e-08
Identities = 24/60 (40%), Positives = 33/60 (55%), Gaps = 1/60 (1%)
Frame = +2
Query: 29 WKCDGENDCGNNFDESRC-TETDNMCNNVKFNCKDGKVIPRAYQCDKEADCVNGDDEIGC 205
W CDG NDCG+ DE +C + + C F+C G+ I + CD + DC +G DE C
Sbjct: 2657 WICDGSNDCGDYSDELKCPVQNKHKCEENYFSCPSGRCILNTWICDGQKDCEDGRDEFHC 2716
Score = 57.0 bits (136), Expect = 4e-08
Identities = 27/83 (32%), Positives = 41/83 (49%)
Frame = +2
Query: 35 CDGENDCGNNFDESRCTETDNMCNNVKFNCKDGKVIPRAYQCDKEADCVNGDDEIGCVLP 214
CDG+ DC + DE C + C+ +F C +G+ IP ++CD DC G+DE C
Sbjct: 3534 CDGDFDCADGSDERNC---ETSCSKDQFRCSNGQCIPAKWKCDGHEDCKYGEDEKSCEPA 3590
Query: 215 QVTSTTSDKVKRVRRGSSLELKC 283
T ++ + + S LKC
Sbjct: 3591 SPTCSSREYICASDGCISASLKC 3613
Score = 57.0 bits (136), Expect = 4e-08
Identities = 28/74 (37%), Positives = 37/74 (50%), Gaps = 4/74 (5%)
Frame = +2
Query: 35 CDGENDCGNNFDESRC----TETDNMCNNVKFNCKDGKVIPRAYQCDKEADCVNGDDEIG 202
C+G ++CG+N DE C T C +F C + K IP QCD+ DC +G DE G
Sbjct: 3736 CNGIDECGDNSDEDHCGGKLTYKARPCKKDEFACSNKKCIPMDLQCDRLDDCGDGSDEQG 3795
Query: 203 CVLPQVTSTTSDKV 244
C + T D V
Sbjct: 3796 CRIAPTEYTCEDNV 3809
Score = 56.6 bits (135), Expect = 5e-08
Identities = 25/61 (40%), Positives = 36/61 (59%), Gaps = 2/61 (3%)
Frame = +2
Query: 29 WKCDGENDCGNNFDESRCTETDNMCNN-VKFNC-KDGKVIPRAYQCDKEADCVNGDDEIG 202
W+CDGE DC + DE C T +C++ KF+C G+ I +A+ CD + DC + DE
Sbjct: 1071 WRCDGEKDCEDGSDEKGCNGTIRLCDHKTKFSCWSTGRCINKAWVCDGDIDCEDQSDEDD 1130
Query: 203 C 205
C
Sbjct: 1131 C 1131
Score = 56.6 bits (135), Expect = 5e-08
Identities = 27/64 (42%), Positives = 36/64 (56%), Gaps = 4/64 (6%)
Frame = +2
Query: 26 HWKCDGENDCGNNFDESRCTETDNMCNNVKFNCKDGKV-IPRAYQCDKEADCVNGDDEI- 199
HW CDGE+DCG+ DES C F+C+ + +PR + CD E DC +G DE+
Sbjct: 2736 HWICDGEDDCGDGLDESDSICGAITCAADMFSCQGSRACVPRHWLCDGERDCPDGSDELS 2795
Query: 200 --GC 205
GC
Sbjct: 2796 TAGC 2799
Score = 55.5 bits (132), Expect = 1e-07
Identities = 22/60 (36%), Positives = 31/60 (51%)
Frame = +2
Query: 29 WKCDGENDCGNNFDESRCTETDNMCNNVKFNCKDGKVIPRAYQCDKEADCVNGDDEIGCV 208
WKCDG DC DE C C++ ++ C I + +C+ E DC +G DE+ CV
Sbjct: 3570 WKCDGHEDCKYGEDEKSCEPASPTCSSREYICASDGCISASLKCNGEYDCADGSDEMDCV 3629
Score = 53.1 bits (126), Expect = 5e-07
Identities = 20/56 (35%), Positives = 34/56 (60%)
Frame = +2
Query: 29 WKCDGENDCGNNFDESRCTETDNMCNNVKFNCKDGKVIPRAYQCDKEADCVNGDDE 196
WKCDG++DC + DE ++ C + +F C++ + IP+ + CD DC + +DE
Sbjct: 862 WKCDGDDDCLDGSDEDSVNCFNHSCPDDQFKCQNNRCIPKRWLCDGANDCGSNEDE 917
Score = 52.4 bits (124), Expect = 9e-07
Identities = 24/68 (35%), Positives = 36/68 (52%), Gaps = 2/68 (2%)
Frame = +2
Query: 29 WKCDGENDCGNNFDESRCTETDNMCNNVKFNCKDGKVIPRAYQCDKEADCVNGDDE--IG 202
W CD ++DCG+ DE C + C + +F C G+ IP + CD + DC + DE I
Sbjct: 985 WHCDSDDDCGDGSDEVGCVHS---CFDNQFRCSSGRCIPGHWACDGDNDCGDFSDEAQIN 1041
Query: 203 CVLPQVTS 226
C ++ S
Sbjct: 1042 CTKEEIHS 1049
Score = 52.4 bits (124), Expect = 9e-07
Identities = 23/59 (38%), Positives = 31/59 (52%), Gaps = 2/59 (3%)
Frame = +2
Query: 26 HWKCDGENDCGNNFDESRCT--ETDNMCNNVKFNCKDGKVIPRAYQCDKEADCVNGDDE 196
HW CDGE DC + DE +N C+ F C + IP+ + CD + DC +G DE
Sbjct: 2778 HWLCDGERDCPDGSDELSTAGCAPNNTCDENAFMCHNKVCIPKQFVCDHDDDCGDGSDE 2836
Score = 52.4 bits (124), Expect = 9e-07
Identities = 24/62 (38%), Positives = 36/62 (58%), Gaps = 1/62 (1%)
Frame = +2
Query: 23 VHWKCDGENDCGNNFDESRCTETDNMCNNVKFNCKDGK-VIPRAYQCDKEADCVNGDDEI 199
V+ +C+G++DCG+ DE C E N C+ F CK K I + + CD++ DC + DE
Sbjct: 3412 VNLRCNGQDDCGDEEDERDCPE--NSCSPDYFQCKTTKHCISKLWVCDEDPDCADASDEA 3469
Query: 200 GC 205
C
Sbjct: 3470 NC 3471
Score = 51.6 bits (122), Expect = 2e-06
Identities = 25/58 (43%), Positives = 36/58 (62%), Gaps = 1/58 (1%)
Frame = +2
Query: 35 CDGENDCGNNFDESRCTETDNMCNNVKFNC-KDGKVIPRAYQCDKEADCVNGDDEIGC 205
CDGENDCG+N DE C ++C + +F C K+ K IP +C+ + DC + +DE C
Sbjct: 3376 CDGENDCGDNSDELNC--DTHVCLSGQFKCTKNQKCIPVNLRCNGQDDCGDEEDERDC 3431
Score = 51.6 bits (122), Expect = 2e-06
Identities = 21/59 (35%), Positives = 31/59 (52%)
Frame = +2
Query: 29 WKCDGENDCGNNFDESRCTETDNMCNNVKFNCKDGKVIPRAYQCDKEADCVNGDDEIGC 205
W CD + DC + DE+ C + C +F CK+ IP ++CD + DC + DE C
Sbjct: 3454 WVCDEDPDCADASDEANCDK--KTCGPHEFQCKNNNCIPDHWRCDSQNDCSDNSDEENC 3510
Score = 49.3 bits (116), Expect = 8e-06
Identities = 24/65 (36%), Positives = 34/65 (52%)
Frame = +2
Query: 29 WKCDGENDCGNNFDESRCTETDNMCNNVKFNCKDGKVIPRAYQCDKEADCVNGDDEIGCV 208
W CDG+ DC + DE C D+ C+ +F C K I + + CD E DC +G DE +
Sbjct: 2699 WICDGQKDCEDGRDEFHC---DSSCSWNQFACSAQKCISKHWICDGEDDCGDGLDESDSI 2755
Query: 209 LPQVT 223
+T
Sbjct: 2756 CGAIT 2760
Score = 47.8 bits (112), Expect = 2e-05
Identities = 24/60 (40%), Positives = 30/60 (50%), Gaps = 1/60 (1%)
Frame = +2
Query: 29 WKCDGENDCGNNFDE-SRCTETDNMCNNVKFNCKDGKVIPRAYQCDKEADCVNGDDEIGC 205
WKCD +DCG+ DE C E C +F C G A+ CD E DC + DE+ C
Sbjct: 3334 WKCDTVDDCGDGSDEPDDCPEF--RCQPGRFQCGTGLCALPAFICDGENDCGDNSDELNC 3391
Score = 47.8 bits (112), Expect = 2e-05
Identities = 20/58 (34%), Positives = 28/58 (48%)
Frame = +2
Query: 23 VHWKCDGENDCGNNFDESRCTETDNMCNNVKFNCKDGKVIPRAYQCDKEADCVNGDDE 196
+ W CDG +DC + DE C N+C +F C + + CD E DC + DE
Sbjct: 3648 IRWLCDGIHDCVDGSDEENCERGGNICRADEFLCNNSLCKLHFWVCDGEDDCGDNSDE 3705
Score = 47.4 bits (111), Expect = 3e-05
Identities = 24/59 (40%), Positives = 30/59 (50%), Gaps = 1/59 (1%)
Frame = +2
Query: 32 KCDGENDCGNNFDESRCTETDNMCNNVKFNCKD-GKVIPRAYQCDKEADCVNGDDEIGC 205
KC+GE DC + DE C C +F CK+ IP + CD DCV+G DE C
Sbjct: 3612 KCNGEYDCADGSDEMDCVTE---CKEDQFRCKNKAHCIPIRWLCDGIHDCVDGSDEENC 3667
Score = 37.0 bits (84), Expect = 0.039
Identities = 18/57 (31%), Positives = 24/57 (42%)
Frame = +2
Query: 35 CDGENDCGNNFDESRCTETDNMCNNVKFNCKDGKVIPRAYQCDKEADCVNGDDEIGC 205
CDG C + DE + C C + + IP CD E DC + DE+ C
Sbjct: 2530 CDGIPHCKDKSDEKLLYCENRSCRRGFKPCYNRRCIPHGKLCDGENDCGDNSDELDC 2586
Score = 34.7 bits (78), Expect = 0.20
Identities = 19/52 (36%), Positives = 23/52 (44%), Gaps = 4/52 (7%)
Frame = +2
Query: 53 CGNNF----DESRCTETDNMCNNVKFNCKDGKVIPRAYQCDKEADCVNGDDE 196
C NF D C C +F CK K IP ++CD DC +G DE
Sbjct: 3300 CPTNFYLAADNRTCLSN---CTASQFRCKTDKCIPFWWKCDTVDDCGDGSDE 3348
Score = 34.3 bits (77), Expect = 0.25
Identities = 19/57 (33%), Positives = 29/57 (50%), Gaps = 9/57 (15%)
Frame = +2
Query: 53 CGNN--FDESRCTETDN-------MCNNVKFNCKDGKVIPRAYQCDKEADCVNGDDE 196
C +N DE+ T T N +C +F CK+ I ++CD + DC++G DE
Sbjct: 820 CADNQLLDENGTTCTFNPGEALPHICKAGEFRCKNRHCIQARWKCDGDDDCLDGSDE 876
Score = 32.7 bits (73), Expect = 0.74
Identities = 20/60 (33%), Positives = 28/60 (46%), Gaps = 4/60 (6%)
Frame = +2
Query: 29 WKCDGENDCGNNFDESRCT---ETDNMCNNVKFNC-KDGKVIPRAYQCDKEADCVNGDDE 196
W CDG+ DC ++ DES T E + C C K + + C+ DC +G DE
Sbjct: 50 WLCDGDPDCPDDSDESLDTCPEEVEIKCPLNHIACLGTNKCVHLSQLCNGVLDCPDGYDE 109
Score = 30.0 bits (66), Expect = 4.8
Identities = 18/67 (26%), Positives = 27/67 (40%), Gaps = 9/67 (13%)
Frame = +2
Query: 32 KCDGENDCGNNFDESRCTETD---------NMCNNVKFNCKDGKVIPRAYQCDKEADCVN 184
+C+ DC + DE C TD ++ N V+P + CD DC +
Sbjct: 2609 RCNQNIDCADASDEKNCNNTDCTHFYKLGVKTTGFIRCNSTSLCVLP-TWICDGSNDCGD 2667
Query: 185 GDDEIGC 205
DE+ C
Sbjct: 2668 YSDELKC 2674
>sp|Q9JI18|LRP1B_MOUSE Low-density lipoprotein receptor-related protein 1B precursor
(Low-density lipoprotein receptor-related protein-deleted
in tumor) (LRP-DIT)
Length = 4599
Score = 67.0 bits (162), Expect = 4e-11
Identities = 30/63 (47%), Positives = 39/63 (61%), Gaps = 1/63 (1%)
Frame = +2
Query: 29 WKCDGENDCGNNFDESRCTETDNMCNNVKFNCKDGKVIPRAYQCDKEADCVNGDDEI-GC 205
W CDG NDCG+N DES T T C +F+C +G+ IP A+ CD+E DC + DE+ C
Sbjct: 903 WLCDGANDCGSNEDESNQTCTARTCQADQFSCGNGRCIPTAWLCDREDDCGDQTDEVASC 962
Query: 206 VLP 214
P
Sbjct: 963 EFP 965
Score = 63.2 bits (152), Expect = 5e-10
Identities = 30/67 (44%), Positives = 40/67 (59%), Gaps = 7/67 (10%)
Frame = +2
Query: 26 HWKCDGENDCGNNFDESR--CTETDNM----CNNVKFNCK-DGKVIPRAYQCDKEADCVN 184
HW CDG+NDCG+ DE+ CT+ + C +F C+ DG IP ++CD E DC +
Sbjct: 1022 HWACDGDNDCGDFSDETHINCTKEEARSPAGCIGNEFQCRPDGNCIPDLWRCDGEKDCED 1081
Query: 185 GDDEIGC 205
G DE GC
Sbjct: 1082 GSDEKGC 1088
Score = 62.0 bits (149), Expect = 1e-09
Identities = 26/57 (45%), Positives = 36/57 (63%)
Frame = +2
Query: 35 CDGENDCGNNFDESRCTETDNMCNNVKFNCKDGKVIPRAYQCDKEADCVNGDDEIGC 205
CDG NDCG++ DE C + C+ V+F C DG IPR+ +C++ DC + DE GC
Sbjct: 2571 CDGTNDCGDSSDELDCKVST--CSTVEFRCADGTCIPRSARCNQNMDCSDASDEKGC 2625
Score = 61.2 bits (147), Expect = 2e-09
Identities = 29/92 (31%), Positives = 47/92 (51%), Gaps = 4/92 (4%)
Frame = +2
Query: 29 WKCDGENDCGNNFDES----RCTETDNMCNNVKFNCKDGKVIPRAYQCDKEADCVNGDDE 196
W+CDG+ DC ++ DE+ RC ++ CN+ F CK+G+ IP CD DC +G DE
Sbjct: 2863 WQCDGDFDCPDSSDEAPINPRCRSAEHSCNSSFFMCKNGRCIPSDGLCDIRDDCGDGSDE 2922
Query: 197 IGCVLPQVTSTTSDKVKRVRRGSSLELKCESY 292
C + + S + + + KC+ +
Sbjct: 2923 TNCHINECLSKKISGCSQDCQDLPVSYKCKCW 2954
Score = 60.8 bits (146), Expect = 3e-09
Identities = 23/61 (37%), Positives = 35/61 (57%)
Frame = +2
Query: 29 WKCDGENDCGNNFDESRCTETDNMCNNVKFNCKDGKVIPRAYQCDKEADCVNGDDEIGCV 208
WKCDG DC DE C +C++ ++ C G + + +C+ E DCV+G DE+ CV
Sbjct: 3570 WKCDGHEDCKYGEDEKNCEPAFPVCSSSEYMCASGGCLSASLKCNGEPDCVDGSDEMDCV 3629
Query: 209 L 211
+
Sbjct: 3630 I 3630
Score = 60.1 bits (144), Expect = 4e-09
Identities = 24/60 (40%), Positives = 31/60 (51%)
Frame = +2
Query: 26 HWKCDGENDCGNNFDESRCTETDNMCNNVKFNCKDGKVIPRAYQCDKEADCVNGDDEIGC 205
HW+CD +NDC +N DE C C F C +G + + CD E DC +G DE C
Sbjct: 3492 HWRCDNQNDCSDNSDEDNC--KPQTCTLKDFLCSNGDCVSSRFWCDGEFDCADGSDEKNC 3549
Score = 58.2 bits (139), Expect = 2e-08
Identities = 25/63 (39%), Positives = 34/63 (53%), Gaps = 1/63 (1%)
Frame = +2
Query: 20 LVHWKCDGENDCGNNFDESRC-TETDNMCNNVKFNCKDGKVIPRAYQCDKEADCVNGDDE 196
L W CDG NDCG+ DE +C + + C F C G+ I + CD + DC +G DE
Sbjct: 2654 LPSWICDGSNDCGDYSDELKCPVQNKHKCEENYFGCPSGRCILNTWVCDGQKDCEDGLDE 2713
Query: 197 IGC 205
+ C
Sbjct: 2714 LHC 2716
Score = 57.4 bits (137), Expect = 3e-08
Identities = 25/61 (40%), Positives = 36/61 (59%), Gaps = 2/61 (3%)
Frame = +2
Query: 29 WKCDGENDCGNNFDESRCTETDNMCNN-VKFNCKD-GKVIPRAYQCDKEADCVNGDDEIG 202
W+CDGE DC + DE C T +C++ KF+C+ G+ I A+ CD + DC + DE
Sbjct: 1071 WRCDGEKDCEDGSDEKGCNGTIRLCDHKTKFSCRSTGRCINNAWVCDGDVDCEDQSDEED 1130
Query: 203 C 205
C
Sbjct: 1131 C 1131
Score = 56.6 bits (135), Expect = 5e-08
Identities = 26/69 (37%), Positives = 36/69 (52%), Gaps = 4/69 (5%)
Frame = +2
Query: 35 CDGENDCGNNFDESRCTETDNM----CNNVKFNCKDGKVIPRAYQCDKEADCVNGDDEIG 202
C+G NDCG+N DE C+ ++ C +F C + IP QCD DC +G DE G
Sbjct: 3736 CNGINDCGDNSDEEHCSGKLSLKSKPCKKDEFTCSNRNCIPMELQCDSLDDCGDGSDEQG 3795
Query: 203 CVLPQVTST 229
C+ + T
Sbjct: 3796 CLKTPIEHT 3804
Score = 55.8 bits (133), Expect = 8e-08
Identities = 24/60 (40%), Positives = 32/60 (53%)
Frame = +2
Query: 29 WKCDGENDCGNNFDESRCTETDNMCNNVKFNCKDGKVIPRAYQCDKEADCVNGDDEIGCV 208
W CD E+DCG+ DE E +F CK G+ I + CD + DC + DE+GCV
Sbjct: 944 WLCDREDDCGDQTDEVASCEFPTCEPLTQFICKSGRCISNKWHCDTDDDCGDRSDEVGCV 1003
Score = 55.1 bits (131), Expect = 1e-07
Identities = 21/56 (37%), Positives = 35/56 (62%)
Frame = +2
Query: 29 WKCDGENDCGNNFDESRCTETDNMCNNVKFNCKDGKVIPRAYQCDKEADCVNGDDE 196
WKCDG++DC + DE T ++ C + +F C++ + IP+ + CD DC + +DE
Sbjct: 862 WKCDGDDDCLDGSDEDSVTCFNHSCPDDQFKCQNNRCIPKRWLCDGANDCGSNEDE 917
Score = 54.7 bits (130), Expect = 2e-07
Identities = 28/69 (40%), Positives = 40/69 (57%), Gaps = 9/69 (13%)
Frame = +2
Query: 26 HWKCDGENDCGNNFDESRCTETDNMCNNV-----KFNCKDGKV-IPRAYQCDKEADCVNG 187
HW CDGE+DCG++ DES D++C V F+C+ +P+ + CD E DC +G
Sbjct: 2736 HWICDGEDDCGDSLDES-----DSICGAVTCAADMFSCQGSHACVPQHWLCDGERDCPDG 2790
Query: 188 DDEI---GC 205
DE+ GC
Sbjct: 2791 SDELSSAGC 2799
Score = 53.5 bits (127), Expect = 4e-07
Identities = 24/59 (40%), Positives = 32/59 (54%), Gaps = 2/59 (3%)
Frame = +2
Query: 26 HWKCDGENDCGNNFDE--SRCTETDNMCNNVKFNCKDGKVIPRAYQCDKEADCVNGDDE 196
HW CDGE DC + DE S +N C+ F C + IP+ + CD + DC +G DE
Sbjct: 2778 HWLCDGERDCPDGSDELSSAGCAPNNTCDENAFMCHNKVCIPKQFVCDHDDDCGDGSDE 2836
Score = 52.8 bits (125), Expect = 7e-07
Identities = 24/62 (38%), Positives = 36/62 (58%), Gaps = 1/62 (1%)
Frame = +2
Query: 23 VHWKCDGENDCGNNFDESRCTETDNMCNNVKFNCKDGK-VIPRAYQCDKEADCVNGDDEI 199
V+ +C+G++DCG+ DE C E N C+ F CK K I + + CD++ DC + DE
Sbjct: 3412 VNLRCNGQDDCGDEEDEKDCPE--NSCSPDYFQCKTTKHCISKLWVCDEDPDCADASDEA 3469
Query: 200 GC 205
C
Sbjct: 3470 NC 3471
Score = 52.8 bits (125), Expect = 7e-07
Identities = 26/83 (31%), Positives = 40/83 (48%)
Frame = +2
Query: 35 CDGENDCGNNFDESRCTETDNMCNNVKFNCKDGKVIPRAYQCDKEADCVNGDDEIGCVLP 214
CDGE DC + DE C + C+ +F C +G+ + ++CD DC G+DE C
Sbjct: 3534 CDGEFDCADGSDEKNC---ETSCSKDQFQCSNGQCLSAKWKCDGHEDCKYGEDEKNCEPA 3590
Query: 215 QVTSTTSDKVKRVRRGSSLELKC 283
++S+ + S LKC
Sbjct: 3591 FPVCSSSEYMCASGGCLSASLKC 3613
Score = 51.6 bits (122), Expect = 2e-06
Identities = 21/59 (35%), Positives = 31/59 (52%)
Frame = +2
Query: 29 WKCDGENDCGNNFDESRCTETDNMCNNVKFNCKDGKVIPRAYQCDKEADCVNGDDEIGC 205
W CD + DC + DE+ C + C +F CK+ IP ++CD + DC + DE C
Sbjct: 3454 WVCDEDPDCADASDEANCDK--KTCGPHEFQCKNNNCIPDHWRCDNQNDCSDNSDEDNC 3510
Score = 50.8 bits (120), Expect = 3e-06
Identities = 24/68 (35%), Positives = 35/68 (51%), Gaps = 2/68 (2%)
Frame = +2
Query: 29 WKCDGENDCGNNFDESRCTETDNMCNNVKFNCKDGKVIPRAYQCDKEADCVNGDDE--IG 202
W CD ++DCG+ DE C + C + +F C G+ IP + CD + DC + DE I
Sbjct: 985 WHCDTDDDCGDRSDEVGCVHS---CLDDQFRCSSGRCIPGHWACDGDNDCGDFSDETHIN 1041
Query: 203 CVLPQVTS 226
C + S
Sbjct: 1042 CTKEEARS 1049
Score = 50.4 bits (119), Expect = 3e-06
Identities = 25/58 (43%), Positives = 35/58 (60%), Gaps = 1/58 (1%)
Frame = +2
Query: 35 CDGENDCGNNFDESRCTETDNMCNNVKFNC-KDGKVIPRAYQCDKEADCVNGDDEIGC 205
CDGENDCG+N DE C ++C +F C K+ K IP +C+ + DC + +DE C
Sbjct: 3376 CDGENDCGDNSDELNC--DTHVCLAGQFKCTKNKKCIPVNLRCNGQDDCGDEEDEKDC 3431
Score = 48.5 bits (114), Expect = 1e-05
Identities = 24/65 (36%), Positives = 33/65 (50%)
Frame = +2
Query: 29 WKCDGENDCGNNFDESRCTETDNMCNNVKFNCKDGKVIPRAYQCDKEADCVNGDDEIGCV 208
W CDG+ DC + DE C D+ C+ +F C K I + + CD E DC + DE +
Sbjct: 2699 WVCDGQKDCEDGLDELHC---DSSCSWNQFACSVKKCISKHWICDGEDDCGDSLDESDSI 2755
Query: 209 LPQVT 223
VT
Sbjct: 2756 CGAVT 2760
Score = 47.8 bits (112), Expect = 2e-05
Identities = 24/60 (40%), Positives = 30/60 (50%), Gaps = 1/60 (1%)
Frame = +2
Query: 29 WKCDGENDCGNNFDE-SRCTETDNMCNNVKFNCKDGKVIPRAYQCDKEADCVNGDDEIGC 205
WKCD +DCG+ DE C E C +F C G A+ CD E DC + DE+ C
Sbjct: 3334 WKCDTVDDCGDGSDEPDDCPEFK--CQPGRFQCGTGLCALPAFICDGENDCGDNSDELNC 3391
Score = 45.1 bits (105), Expect = 1e-04
Identities = 19/58 (32%), Positives = 28/58 (48%)
Frame = +2
Query: 23 VHWKCDGENDCGNNFDESRCTETDNMCNNVKFNCKDGKVIPRAYQCDKEADCVNGDDE 196
+ W CDG DC + DE C ++C + +F C + + CD E DC + DE
Sbjct: 3648 IRWLCDGIYDCVDGSDEETCGRGGSICRDDEFLCNNSLCKLHFWVCDGEDDCGDNSDE 3705
Score = 44.3 bits (103), Expect = 2e-04
Identities = 24/59 (40%), Positives = 30/59 (50%), Gaps = 1/59 (1%)
Frame = +2
Query: 32 KCDGENDCGNNFDESRCTETDNMCNNVKFNCKD-GKVIPRAYQCDKEADCVNGDDEIGC 205
KC+GE DC + DE C C +F CK+ IP + CD DCV+G DE C
Sbjct: 3612 KCNGEPDCVDGSDEMDCVIE---CKEDQFQCKNKAYCIPIRWLCDGIYDCVDGSDEETC 3667
Score = 34.7 bits (78), Expect = 0.20
Identities = 16/57 (28%), Positives = 24/57 (42%)
Frame = +2
Query: 35 CDGENDCGNNFDESRCTETDNMCNNVKFNCKDGKVIPRAYQCDKEADCVNGDDEIGC 205
CDG C + DE + C + C + + +P CD DC + DE+ C
Sbjct: 2530 CDGIPHCKDKSDEKLLYCENRSCRSGFKPCYNRRCVPHGKLCDGTNDCGDSSDELDC 2586
Score = 34.7 bits (78), Expect = 0.20
Identities = 19/52 (36%), Positives = 23/52 (44%), Gaps = 4/52 (7%)
Frame = +2
Query: 53 CGNNF----DESRCTETDNMCNNVKFNCKDGKVIPRAYQCDKEADCVNGDDE 196
C NF D C C +F CK K IP ++CD DC +G DE
Sbjct: 3300 CPTNFYLAADNRTCLSN---CTASQFRCKTDKCIPFWWKCDTVDDCGDGSDE 3348
Score = 34.3 bits (77), Expect = 0.25
Identities = 19/57 (33%), Positives = 29/57 (50%), Gaps = 9/57 (15%)
Frame = +2
Query: 53 CGNN--FDESRCTETDN-------MCNNVKFNCKDGKVIPRAYQCDKEADCVNGDDE 196
C +N DE+ T T N +C +F CK+ I ++CD + DC++G DE
Sbjct: 820 CADNQLLDENGTTCTFNPEEIRFHICKPGEFRCKNKHCIQARWKCDGDDDCLDGSDE 876
Score = 32.0 bits (71), Expect = 1.3
Identities = 20/62 (32%), Positives = 27/62 (43%), Gaps = 4/62 (6%)
Frame = +2
Query: 29 WKCDGENDCGNNFDESRCT---ETDNMCNNVKFNCKDGKV-IPRAYQCDKEADCVNGDDE 196
W CDG+ DC + DES T E + C C + + C+ DC +G DE
Sbjct: 50 WLCDGDPDCPDQSDESLDTCPEEVEIKCPLNHIACHGSSACVHLSKLCNGVVDCPDGFDE 109
Query: 197 IG 202
G
Sbjct: 110 GG 111
Score = 30.0 bits (66), Expect = 4.8
Identities = 18/67 (26%), Positives = 28/67 (41%), Gaps = 9/67 (13%)
Frame = +2
Query: 32 KCDGENDCGNNFDESRCTETD---------NMCNNVKFNCKDGKVIPRAYQCDKEADCVN 184
+C+ DC + DE C TD ++ N V+P ++ CD DC +
Sbjct: 2609 RCNQNMDCSDASDEKGCNNTDCTHFYKLGVKSTGFIRCNSTSLCVLP-SWICDGSNDCGD 2667
Query: 185 GDDEIGC 205
DE+ C
Sbjct: 2668 YSDELKC 2674
Score = 29.3 bits (64), Expect = 8.2
Identities = 13/35 (37%), Positives = 19/35 (54%), Gaps = 2/35 (5%)
Frame = +2
Query: 32 KCDGENDCGNNFDESRCTET--DNMCNNVKFNCKD 130
+CD +DCG+ DE C +T ++ C N C D
Sbjct: 3780 QCDSLDDCGDGSDEQGCLKTPIEHTCENNGNPCGD 3814
>sp|Q07954|LRP1_HUMAN Low-density lipoprotein receptor-related protein 1 precursor (LRP)
(Alpha-2-macroglobulin receptor) (A2MR) (Apolipoprotein E
receptor) (APOER) (CD91)
Length = 4544
Score = 67.0 bits (162), Expect = 4e-11
Identities = 27/59 (45%), Positives = 37/59 (62%)
Frame = +2
Query: 29 WKCDGENDCGNNFDESRCTETDNMCNNVKFNCKDGKVIPRAYQCDKEADCVNGDDEIGC 205
WKCDG++DC + DE CT C+ +F CK G IP ++CD +ADC++G DE C
Sbjct: 3592 WKCDGDHDCADGSDEKDCTPR---CDMDQFQCKSGHCIPLRWRCDADADCMDGSDEEAC 3647
Score = 63.2 bits (152), Expect = 5e-10
Identities = 24/59 (40%), Positives = 35/59 (59%)
Frame = +2
Query: 29 WKCDGENDCGNNFDESRCTETDNMCNNVKFNCKDGKVIPRAYQCDKEADCVNGDDEIGC 205
WKCDGE+DCG+ DE + + C +F CK+ + +P +QCD + DC + DE C
Sbjct: 3512 WKCDGEDDCGDGSDEPKEECDERTCEPYQFRCKNNRCVPGRWQCDYDNDCGDNSDEESC 3570
Score = 63.2 bits (152), Expect = 5e-10
Identities = 25/59 (42%), Positives = 37/59 (62%)
Frame = +2
Query: 29 WKCDGENDCGNNFDESRCTETDNMCNNVKFNCKDGKVIPRAYQCDKEADCVNGDDEIGC 205
W+CD +NDCG+N DE CT C+ +F+C +G+ I ++CD + DC +G DE C
Sbjct: 3553 WQCDYDNDCGDNSDEESCTPRP--CSESEFSCANGRCIAGRWKCDGDHDCADGSDEKDC 3609
Score = 62.8 bits (151), Expect = 7e-10
Identities = 23/58 (39%), Positives = 38/58 (65%)
Frame = +2
Query: 23 VHWKCDGENDCGNNFDESRCTETDNMCNNVKFNCKDGKVIPRAYQCDKEADCVNGDDE 196
++W+CD +NDCG+N DE+ C+ + C++ +F C G+ IP + CD + DC + DE
Sbjct: 992 INWRCDNDNDCGDNSDEAGCSHS---CSSTQFKCNSGRCIPEHWTCDGDNDCGDYSDE 1046
Score = 62.0 bits (149), Expect = 1e-09
Identities = 27/63 (42%), Positives = 37/63 (58%), Gaps = 1/63 (1%)
Frame = +2
Query: 29 WKCDGENDCGNNFDESRCTETDNMCNNVKFNCKDGKVIPRAYQCDKEADCVNGDDE-IGC 205
W CDG+NDCGN+ DES T + C +F+C G+ IP ++ CD + DC + DE C
Sbjct: 912 WLCDGDNDCGNSEDESNATCSARTCPPNQFSCASGRCIPISWTCDLDDDCGDRSDESASC 971
Query: 206 VLP 214
P
Sbjct: 972 AYP 974
Score = 60.8 bits (146), Expect = 3e-09
Identities = 28/69 (40%), Positives = 35/69 (50%), Gaps = 1/69 (1%)
Frame = +2
Query: 2 RLKTVFLVHWKCDGENDCGNNFDESRCTETDN-MCNNVKFNCKDGKVIPRAYQCDKEADC 178
R + W CDG NDCG+ DE C C F C G+ IP ++ CDKE DC
Sbjct: 2662 RTSLCYAPSWVCDGANDCGDYSDERDCPGVKRPRCPLNYFACPSGRCIPMSWTCDKEDDC 2721
Query: 179 VNGDDEIGC 205
+G+DE C
Sbjct: 2722 EHGEDETHC 2730
Score = 59.7 bits (143), Expect = 6e-09
Identities = 23/56 (41%), Positives = 35/56 (62%)
Frame = +2
Query: 29 WKCDGENDCGNNFDESRCTETDNMCNNVKFNCKDGKVIPRAYQCDKEADCVNGDDE 196
WKCDG+NDC +N DE+ + C + +F C++ + IP + CD + DC N +DE
Sbjct: 871 WKCDGDNDCLDNSDEAPALCHQHTCPSDRFKCENNRCIPNRWLCDGDNDCGNSEDE 926
Score = 59.7 bits (143), Expect = 6e-09
Identities = 26/67 (38%), Positives = 38/67 (56%), Gaps = 7/67 (10%)
Frame = +2
Query: 26 HWKCDGENDCGNNFDE------SRCTETDNMCNNVKFNCK-DGKVIPRAYQCDKEADCVN 184
HW CDG+NDCG+ DE ++ T C+ +F C+ DG IP ++CD + DC++
Sbjct: 1031 HWTCDGDNDCGDYSDETHANCTNQATRPPGGCHTDEFQCRLDGLCIPLRWRCDGDTDCMD 1090
Query: 185 GDDEIGC 205
DE C
Sbjct: 1091 SSDEKSC 1097
Score = 59.3 bits (142), Expect = 7e-09
Identities = 25/63 (39%), Positives = 39/63 (61%), Gaps = 2/63 (3%)
Frame = +2
Query: 23 VHWKCDGENDCGNNFDESRCTETDNMCN-NVKFNCKD-GKVIPRAYQCDKEADCVNGDDE 196
+ W+CDG+ DC ++ DE C ++C+ +VKF CKD + I +A+ CD + DC + DE
Sbjct: 1078 LRWRCDGDTDCMDSSDEKSCEGVTHVCDPSVKFGCKDSARCISKAWVCDGDNDCEDNSDE 1137
Query: 197 IGC 205
C
Sbjct: 1138 ENC 1140
Score = 57.8 bits (138), Expect = 2e-08
Identities = 26/71 (36%), Positives = 40/71 (56%), Gaps = 5/71 (7%)
Frame = +2
Query: 29 WKCDGENDCGNNFDES----RCTETDNMCN-NVKFNCKDGKVIPRAYQCDKEADCVNGDD 193
W+CDGENDC + DE+ CT ++ CN + +F C G+ + A C+ + DC + D
Sbjct: 2876 WECDGENDCHDQSDEAPKNPHCTSPEHKCNASSQFLCSSGRCVAEALLCNGQDDCGDSSD 2935
Query: 194 EIGCVLPQVTS 226
E GC + + S
Sbjct: 2936 ERGCHINECLS 2946
Score = 52.8 bits (125), Expect = 7e-07
Identities = 21/58 (36%), Positives = 35/58 (60%), Gaps = 2/58 (3%)
Frame = +2
Query: 29 WKCDGENDCGNNFDESRCTET--DNMCNNVKFNCKDGKVIPRAYQCDKEADCVNGDDE 196
W CDG+ DC + DES ++ C++ +F C++ + IP+ + CD + DC +G DE
Sbjct: 2792 WLCDGDKDCADGADESIAAGCLYNSTCDDREFMCQNRQCIPKHFVCDHDRDCADGSDE 2849
Score = 52.8 bits (125), Expect = 7e-07
Identities = 26/58 (44%), Positives = 35/58 (60%), Gaps = 2/58 (3%)
Frame = +2
Query: 29 WKCDGENDCGNNFDE-SRCTETDNMCNNVKFNCKD-GKVIPRAYQCDKEADCVNGDDE 196
W CD +NDC + DE + CT+ C +F CKD G+ IP ++CD E DC +G DE
Sbjct: 3471 WVCDRDNDCVDGSDEPANCTQMT--CGVDEFRCKDSGRCIPARWKCDGEDDCGDGSDE 3526
Score = 52.4 bits (124), Expect = 9e-07
Identities = 36/95 (37%), Positives = 48/95 (50%), Gaps = 7/95 (7%)
Frame = +2
Query: 29 WKCDGENDCGNNFDESRCTETDNMC-NNVKFNCKDGKV-IPRAYQCDKEADCVNGDDEIG 202
WKCDGE+DCG+N DE+ +C N F CK+ +V + QCD +C +G DE
Sbjct: 3671 WKCDGEDDCGDNSDENPEECARFVCPPNRPFRCKNDRVCLWIGRQCDGTDNCGDGTDEED 3730
Query: 203 CVLPQVTSTTSDKVK-----RVRRGSSLELKCESY 292
C P TT K K R +R S L+C +
Sbjct: 3731 CE-PPTAHTTHCKDKKEFLCRNQRCLSSSLRCNMF 3764
Score = 52.0 bits (123), Expect = 1e-06
Identities = 21/61 (34%), Positives = 32/61 (52%)
Frame = +2
Query: 23 VHWKCDGENDCGNNFDESRCTETDNMCNNVKFNCKDGKVIPRAYQCDKEADCVNGDDEIG 202
+ W CD ++DCG+ DES +F C +G+ I ++CD + DC + DE G
Sbjct: 951 ISWTCDLDDDCGDRSDESASCAYPTCFPLTQFTCNNGRCININWRCDNDNDCGDNSDEAG 1010
Query: 203 C 205
C
Sbjct: 1011 C 1011
Score = 52.0 bits (123), Expect = 1e-06
Identities = 38/136 (27%), Positives = 67/136 (49%), Gaps = 1/136 (0%)
Frame = +2
Query: 35 CDGENDCGNNFDESRCTETDNMCNNVKFNCKD-GKVIPRAYQCDKEADCVNGDDEIGCVL 211
CDG+NDC +N DE+ C ++C +F C + + IP ++C+ + +C +G+DE C
Sbjct: 3393 CDGDNDCQDNSDEANC--DIHVCLPSQFKCTNTNRCIPGIFRCNGQDNCGDGEDERDC-- 3448
Query: 212 PQVTSTTSDKVKRVRRGSSLELKCESYGVPRPHVVWRFNWGCLKDNLRMPVTTQIENCNK 391
P+VT + + S+ +C +PR W C +DN + + + NC +
Sbjct: 3449 PEVTCAPN------QFQCSITKRC----IPRV-------WVCDRDNDCVDGSDEPANCTQ 3491
Query: 392 VISTLRIINFQPGDDG 439
+ T + F+ D G
Sbjct: 3492 M--TCGVDEFRCKDSG 3505
Score = 50.8 bits (120), Expect = 3e-06
Identities = 21/57 (36%), Positives = 33/57 (57%)
Frame = +2
Query: 35 CDGENDCGNNFDESRCTETDNMCNNVKFNCKDGKVIPRAYQCDKEADCVNGDDEIGC 205
C+G +DCG+ DE C +T C +F C+DG I + +C++ DC + DE+ C
Sbjct: 2585 CNGADDCGDGSDEIPCNKT--ACGVGEFRCRDGTCIGNSSRCNQFVDCEDASDEMNC 2639
Score = 50.8 bits (120), Expect = 3e-06
Identities = 20/56 (35%), Positives = 32/56 (57%)
Frame = +2
Query: 29 WKCDGENDCGNNFDESRCTETDNMCNNVKFNCKDGKVIPRAYQCDKEADCVNGDDE 196
W CD E+DC + DE+ C + C+ +F C++ + I + + CD DC +G DE
Sbjct: 2713 WTCDKEDDCEHGEDETHCNK---FCSEAQFECQNHRCISKQWLCDGSDDCGDGSDE 2765
Score = 50.1 bits (118), Expect = 4e-06
Identities = 23/57 (40%), Positives = 35/57 (61%), Gaps = 1/57 (1%)
Frame = +2
Query: 29 WKCDGENDCGNNFDESRCTETDNMCNNVKFNCKDGK-VIPRAYQCDKEADCVNGDDE 196
++C+G+++CG+ DE C E C +F C K IPR + CD++ DCV+G DE
Sbjct: 3431 FRCNGQDNCGDGEDERDCPEVT--CAPNQFQCSITKRCIPRVWVCDRDNDCVDGSDE 3485
Score = 48.9 bits (115), Expect = 1e-05
Identities = 24/60 (40%), Positives = 31/60 (51%), Gaps = 1/60 (1%)
Frame = +2
Query: 29 WKCDGENDCGNNFDE-SRCTETDNMCNNVKFNCKDGKVIPRAYQCDKEADCVNGDDEIGC 205
WKCD E+DCG++ DE C E C +F C G A+ CD + DC + DE C
Sbjct: 3351 WKCDTEDDCGDHSDEPPDCPEF--KCRPGQFQCSTGICTNPAFICDGDNDCQDNSDEANC 3408
Score = 48.1 bits (113), Expect = 2e-05
Identities = 27/75 (36%), Positives = 37/75 (49%), Gaps = 4/75 (5%)
Frame = +2
Query: 29 WKCDGENDCGNNFDESRCTETDNMCNNVKFNCKDGKV-IPRAYQCDKEADCVNGDDE--- 196
W CDG +DCG+ DE+ E C F+C V +P + CD + DC +G DE
Sbjct: 2751 WLCDGSDDCGDGSDEAAHCE-GKTCGPSSFSCPGTHVCVPERWLCDGDKDCADGADESIA 2809
Query: 197 IGCVLPQVTSTTSDK 241
GC+ ST D+
Sbjct: 2810 AGCL---YNSTCDDR 2821
Score = 47.8 bits (112), Expect = 2e-05
Identities = 20/58 (34%), Positives = 29/58 (50%)
Frame = +2
Query: 23 VHWKCDGENDCGNNFDESRCTETDNMCNNVKFNCKDGKVIPRAYQCDKEADCVNGDDE 196
+ W+CD + DC + DE C C +F C + P A++CD E DC + DE
Sbjct: 3628 LRWRCDADADCMDGSDEEACGTGVRTCPLDEFQCNNTLCKPLAWKCDGEDDCGDNSDE 3685
Score = 45.1 bits (105), Expect = 1e-04
Identities = 26/97 (26%), Positives = 48/97 (49%), Gaps = 11/97 (11%)
Frame = +2
Query: 32 KCDGENDCGNNFDESRC----TETDNMCNNVKFNCKDGKVIPRAYQCDKEADCVNGDDEI 199
+CDG ++CG+ DE C T + + +F C++ + + + +C+ DC +G DE
Sbjct: 3715 QCDGTDNCGDGTDEEDCEPPTAHTTHCKDKKEFLCRNQRCLSSSLRCNMFDDCGDGSDEE 3774
Query: 200 GCVL-PQVTSTTS------DKVKRVRRGSSLELKCES 289
C + P++TS + D+ + VR + C S
Sbjct: 3775 DCSIDPKLTSCATNASICGDEARCVRTEKAAYCACRS 3811
Score = 42.4 bits (98), Expect = 0.001
Identities = 21/58 (36%), Positives = 26/58 (44%), Gaps = 2/58 (3%)
Frame = +2
Query: 29 WKCDGENDCGNNFDESRCTETDNMCNNVKFNCKDGKVI--PRAYQCDKEADCVNGDDE 196
W CDG+NDC +N DE C C C + + P CD DC +G DE
Sbjct: 1123 WVCDGDNDCEDNSDEENCESL--ACRPPSHPCANNTSVCLPPDKLCDGNDDCGDGSDE 1178
Score = 42.0 bits (97), Expect = 0.001
Identities = 21/58 (36%), Positives = 31/58 (53%), Gaps = 1/58 (1%)
Frame = +2
Query: 26 HWKCDGENDCGNNFDESRCTETDNMCNNVKFNCKDGKVI-PRAYQCDKEADCVNGDDE 196
H+ CD + DC + DES E C +F C +G+ + R ++CD E DC + DE
Sbjct: 2834 HFVCDHDRDCADGSDESPECEYPT-CGPSEFRCANGRCLSSRQWECDGENDCHDQSDE 2890
Score = 40.8 bits (94), Expect = 0.003
Identities = 20/60 (33%), Positives = 33/60 (55%), Gaps = 4/60 (6%)
Frame = +2
Query: 29 WKCDGENDCGNNFDESR--CTETD-NMCNNVKFNCKDGKV-IPRAYQCDKEADCVNGDDE 196
W+CDGE DC + DE+ C ++ C + NC ++ +P + C+ DC++G DE
Sbjct: 45 WRCDGERDCPDGSDEAPEICPQSKAQRCQPNEHNCLGTELCVPMSRLCNGVQDCMDGSDE 104
Score = 38.1 bits (87), Expect = 0.018
Identities = 17/57 (29%), Positives = 23/57 (40%)
Frame = +2
Query: 35 CDGENDCGNNFDESRCTETDNMCNNVKFNCKDGKVIPRAYQCDKEADCVNGDDEIGC 205
CDG C + DE C C +G+ + C+ DC +G DEI C
Sbjct: 2544 CDGVPHCKDKSDEKPSYCNSRRCKKTFRQCSNGRCVSNMLWCNGADDCGDGSDEIPC 2600
Score = 33.5 bits (75), Expect = 0.43
Identities = 15/40 (37%), Positives = 23/40 (57%), Gaps = 1/40 (2%)
Frame = +2
Query: 101 CNNVKFNCKDG-KVIPRAYQCDKEADCVNGDDEIGCVLPQ 217
C+ +F C+D I + ++CD E DC +G DE + PQ
Sbjct: 27 CSPKQFACRDQITCISKGWRCDGERDCPDGSDEAPEICPQ 66
Score = 33.5 bits (75), Expect = 0.43
Identities = 19/52 (36%), Positives = 24/52 (46%), Gaps = 4/52 (7%)
Frame = +2
Query: 53 CGNNF----DESRCTETDNMCNNVKFNCKDGKVIPRAYQCDKEADCVNGDDE 196
C NF D C C +F CK+ K IP ++CD E DC + DE
Sbjct: 3317 CPTNFYLGSDGRTCVSN---CTASQFVCKNDKCIPFWWKCDTEDDCGDHSDE 3365
Score = 31.2 bits (69), Expect = 2.2
Identities = 15/49 (30%), Positives = 25/49 (51%)
Frame = +2
Query: 101 CNNVKFNCKDGKVIPRAYQCDKEADCVNGDDEIGCVLPQVTSTTSDKVK 247
C +F C + + I ++CD + DC++ DE + Q T SD+ K
Sbjct: 854 CQPGEFACANSRCIQERWKCDGDNDCLDNSDEAPALCHQHT-CPSDRFK 901
>sp|P05156|CFAI_HUMAN Complement factor I precursor (C3B/C4B inactivator) [Contains:
Complement factor I heavy chain; Complement factor I
light chain]
Length = 583
Score = 66.6 bits (161), Expect = 5e-11
Identities = 28/57 (49%), Positives = 34/57 (59%)
Frame = +2
Query: 35 CDGENDCGNNFDESRCTETDNMCNNVKFNCKDGKVIPRAYQCDKEADCVNGDDEIGC 205
CDG NDCG+ DE C C F+CK G IP YQC+ E DC+ G+DE+GC
Sbjct: 241 CDGINDCGDQSDELCC----KACQGKGFHCKSGVCIPSQYQCNGEVDCITGEDEVGC 293
>sp|P98158|LRP2_RAT Low-density lipoprotein receptor-related protein 2 precursor
(Megalin) (Glycoprotein 330) (gp330)
Length = 4660
Score = 66.6 bits (161), Expect = 5e-11
Identities = 27/68 (39%), Positives = 37/68 (54%)
Frame = +2
Query: 29 WKCDGENDCGNNFDESRCTETDNMCNNVKFNCKDGKVIPRAYQCDKEADCVNGDDEIGCV 208
WKCD +NDCG+ DE + C + F C +G+ +P Y+CD DC + DE GC+
Sbjct: 2718 WKCDNDNDCGDGSDELPTVCAFHTCRSTAFTCGNGRCVPYHYRCDYYNDCGDNSDEAGCL 2777
Query: 209 LPQVTSTT 232
STT
Sbjct: 2778 FRNCNSTT 2785
Score = 64.3 bits (155), Expect = 2e-10
Identities = 26/61 (42%), Positives = 36/61 (59%)
Frame = +2
Query: 23 VHWKCDGENDCGNNFDESRCTETDNMCNNVKFNCKDGKVIPRAYQCDKEADCVNGDDEIG 202
+ WKCDG +DCG+N DE C + C+ +F C D + IP + CD+E DC + DE
Sbjct: 3737 LRWKCDGTDDCGDNSDEENCVpre--CSESEFRCADQQCIPSRWVCDQENDCGDNSDERD 3794
Query: 203 C 205
C
Sbjct: 3795 C 3795
Score = 63.9 bits (154), Expect = 3e-10
Identities = 26/61 (42%), Positives = 33/61 (54%)
Frame = +2
Query: 29 WKCDGENDCGNNFDESRCTETDNMCNNVKFNCKDGKVIPRAYQCDKEADCVNGDDEIGCV 208
W CD +NDC + DE C + C +F C D + I Y CD + DC +G DE GCV
Sbjct: 1127 WVCDTDNDCSDGSDEKNC-QASGTCQPTQFRCPDHRCISPLYVCDGDKDCADGSDEAGCV 1185
Query: 209 L 211
L
Sbjct: 1186 L 1186
Score = 61.6 bits (148), Expect = 1e-09
Identities = 26/59 (44%), Positives = 32/59 (54%)
Frame = +2
Query: 29 WKCDGENDCGNNFDESRCTETDNMCNNVKFNCKDGKVIPRAYQCDKEADCVNGDDEIGC 205
W CD ENDCG+N DE C C+ F C G +P+A CD ADC++ DE C
Sbjct: 3778 WVCDQENDCGDNSDERDCEM--KTCHPEHFQCTSGHCVPKALACDGRADCLDASDESAC 3834
Score = 61.2 bits (147), Expect = 2e-09
Identities = 34/108 (31%), Positives = 52/108 (48%), Gaps = 1/108 (0%)
Frame = +2
Query: 29 WKCDGENDCGNNFDESRCTETDNMCNNVKFNC-KDGKVIPRAYQCDKEADCVNGDDEIGC 205
++CDG +DC +N DE +C +N C+ F C + G+ IP + CD++ DC++G DE C
Sbjct: 1042 FRCDGVDDCHDNSDEHQCGVFNNTCSPSAFACVRGGQCIPGQWHCDRQNDCLDGSDEQNC 1101
Query: 206 VLPQVTSTTSDKVKRVRRGSSLELKCESYGVPRPHVVWRFNWGCLKDN 349
+ST S C++ HV +W C DN
Sbjct: 1102 PTHATSSTC----------PSTSFTCDN------HVCIPKDWVCDTDN 1133
Score = 60.8 bits (146), Expect = 3e-09
Identities = 31/71 (43%), Positives = 43/71 (60%), Gaps = 3/71 (4%)
Frame = +2
Query: 29 WKCDGENDCGNNFDESRC-TETDNMCNNVKFNCK-DGKVIPRAYQCDKEADCVNGDDE-I 199
++CDG DC +N DE+ C T MC+ +F C+ DG IP ++CD DC++G DE
Sbjct: 1206 YRCDGVYDCRDNSDEAGCPTRPPGMCHPDEFQCQGDGTCIPNTWECDGHPDCIHGSDEHT 1265
Query: 200 GCVLPQVTSTT 232
GCV P+ S T
Sbjct: 1266 GCV-PKTCSPT 1275
Score = 55.5 bits (132), Expect = 1e-07
Identities = 23/56 (41%), Positives = 36/56 (64%)
Frame = +2
Query: 29 WKCDGENDCGNNFDESRCTETDNMCNNVKFNCKDGKVIPRAYQCDKEADCVNGDDE 196
++CD NDCG+ DE C+ C+ +F C++G+ IPR + CD++ DC +G DE
Sbjct: 3012 FRCDRRNDCGDYSDERGCSYPP--CHANQFTCQNGRCIPRFFVCDEDNDCGDGSDE 3065
Score = 55.1 bits (131), Expect = 1e-07
Identities = 23/61 (37%), Positives = 32/61 (52%), Gaps = 2/61 (3%)
Frame = +2
Query: 29 WKCDGENDCGNNFDESRCTE--TDNMCNNVKFNCKDGKVIPRAYQCDKEADCVNGDDEIG 202
W CD +NDC + DE C T + C + F C + IP+ + CD + DC +G DE
Sbjct: 1084 WHCDRQNDCLDGSDEQNCPTHATSSTCPSTSFTCDNHVCIPKDWVCDTDNDCSDGSDEKN 1143
Query: 203 C 205
C
Sbjct: 1144 C 1144
Score = 55.1 bits (131), Expect = 1e-07
Identities = 23/64 (35%), Positives = 38/64 (59%), Gaps = 1/64 (1%)
Frame = +2
Query: 26 HWKCDGENDCGNNFDE-SRCTETDNMCNNVKFNCKDGKVIPRAYQCDKEADCVNGDDEIG 202
+W CDG+ DC + DE CT C+ +F+C +G+ + ++++CD+ DC + DE G
Sbjct: 2971 YWVCDGDADCSDALDELQNCTM--RTCSAGEFSCANGRCVRQSFRCDRRNDCGDYSDERG 3028
Query: 203 CVLP 214
C P
Sbjct: 3029 CSYP 3032
Score = 54.7 bits (130), Expect = 2e-07
Identities = 25/69 (36%), Positives = 35/69 (50%), Gaps = 1/69 (1%)
Frame = +2
Query: 29 WKCDGENDCGNNFDESR-CTETDNMCNNVKFNCKDGKVIPRAYQCDKEADCVNGDDEIGC 205
W CD + DC + DE + C T C+ + C +G+ IP Y+CD +DC +G DE C
Sbjct: 85 WVCDEDKDCSDGADEQQNCAGTT--CSAQQMTCSNGQCIPSEYRCDHVSDCPDGSDERNC 142
Query: 206 VLPQVTSTT 232
P T
Sbjct: 143 HYPTCDQLT 151
Score = 53.9 bits (128), Expect = 3e-07
Identities = 23/58 (39%), Positives = 34/58 (58%)
Frame = +2
Query: 32 KCDGENDCGNNFDESRCTETDNMCNNVKFNCKDGKVIPRAYQCDKEADCVNGDDEIGC 205
+CD + DC ++ DE+ CT +C+ +F C G+ I RAY CD + DC + DE C
Sbjct: 163 RCDQKVDCRDSSDEANCT---TLCSQKEFECGSGECILRAYVCDHDNDCEDNSDERNC 217
Score = 53.5 bits (127), Expect = 4e-07
Identities = 21/56 (37%), Positives = 32/56 (57%)
Frame = +2
Query: 29 WKCDGENDCGNNFDESRCTETDNMCNNVKFNCKDGKVIPRAYQCDKEADCVNGDDE 196
W+CD NDC +N DE C +F C +G+ IP++++CD + DC + DE
Sbjct: 3613 WQCDSVNDCLDNSDEDTSHCASRTCRPGQFKCNNGRCIPQSWKCDVDNDCGDYSDE 3668
Score = 52.0 bits (123), Expect = 1e-06
Identities = 23/55 (41%), Positives = 32/55 (58%), Gaps = 1/55 (1%)
Frame = +2
Query: 35 CDGENDCGNNFDESRCTETDNMCNNVKFNC-KDGKVIPRAYQCDKEADCVNGDDE 196
CDG+NDCG+ DE+ + C + +F C + IP + CD EADC +G DE
Sbjct: 2843 CDGDNDCGDGSDENPIYCASHTCRSNEFQCLSPQRCIPSYWFCDGEADCADGSDE 2897
Score = 51.6 bits (122), Expect = 2e-06
Identities = 22/57 (38%), Positives = 32/57 (56%)
Frame = +2
Query: 35 CDGENDCGNNFDESRCTETDNMCNNVKFNCKDGKVIPRAYQCDKEADCVNGDDEIGC 205
CD +NDC +N DE C + C +F C +G+ I + + CD + DC + DE GC
Sbjct: 202 CDHDNDCEDNSDERNCNY--DTCGGHQFTCSNGQCINQNWVCDGDDDCQDSGDEDGC 256
Score = 50.8 bits (120), Expect = 3e-06
Identities = 25/63 (39%), Positives = 38/63 (60%), Gaps = 3/63 (4%)
Frame = +2
Query: 26 HWKCDGENDCGNNFDESRCTETDNMCNN-VKFNCKDGKVIPRAYQCDKEADCVNGD--DE 196
H++CD NDCG+N DE+ C + CN+ +F C +G+ IP +Y C+ +C + D DE
Sbjct: 2758 HYRCDYYNDCGDNSDEAGCLFRN--CNSTTEFTCSNGRCIPLSYVCNGINNCHDNDTSDE 2815
Query: 197 IGC 205
C
Sbjct: 2816 KNC 2818
Score = 50.1 bits (118), Expect = 4e-06
Identities = 24/65 (36%), Positives = 34/65 (52%), Gaps = 3/65 (4%)
Frame = +2
Query: 26 HWKCDGENDCGNNFDESR--CTE-TDNMCNNVKFNCKDGKVIPRAYQCDKEADCVNGDDE 196
H C+G +DCG+ DE C + T C + ++ C +G I + Y CD DC + DE
Sbjct: 3902 HQLCNGVDDCGDGSDEKEEHCRKPTHKPCTDTEYKCSNGNCISQHYVCDNVNDCGDLSDE 3961
Query: 197 IGCVL 211
GC L
Sbjct: 3962 TGCNL 3966
Score = 49.7 bits (117), Expect = 6e-06
Identities = 22/58 (37%), Positives = 31/58 (53%), Gaps = 1/58 (1%)
Frame = +2
Query: 26 HWKCDGENDCGNNFDE-SRCTETDNMCNNVKFNCKDGKVIPRAYQCDKEADCVNGDDE 196
+W CDGE DC + DE C + N C +F C +G+ I + CD + DC + DE
Sbjct: 2882 YWFCDGEADCADGSDEPDTCGHSVNTCRASQFQCDNGRCISGNWVCDGDNDCGDMSDE 2939
Score = 49.7 bits (117), Expect = 6e-06
Identities = 26/63 (41%), Positives = 35/63 (55%), Gaps = 4/63 (6%)
Frame = +2
Query: 29 WKCDGENDCGNNFDE--SRCTETDNMCNN-VKFNCKDG-KVIPRAYQCDKEADCVNGDDE 196
WKCD +NDCG+ DE CT C+N +F+CK + IP+ C+ DC + DE
Sbjct: 3654 WKCDVDNDCGDYSDEPIDECTTAAYNCDNHTEFSCKTNYRCIPQWAVCNGFDDCRDNSDE 3713
Query: 197 IGC 205
GC
Sbjct: 3714 QGC 3716
Score = 48.5 bits (114), Expect = 1e-05
Identities = 22/64 (34%), Positives = 37/64 (57%), Gaps = 6/64 (9%)
Frame = +2
Query: 26 HWKCDGENDCGNNFDESRCTETD-NMCNNVKFNCKDG-----KVIPRAYQCDKEADCVNG 187
+W CDG+NDCG+ DE + + C++ +F C + + IP+ + CD +ADC +
Sbjct: 2924 NWVCDGDNDCGDMSDEDQRHHCELQNCSSTQFTCVNSRPPNRRCIPQYWVCDGDADCSDA 2983
Query: 188 DDEI 199
DE+
Sbjct: 2984 LDEL 2987
Score = 47.4 bits (111), Expect = 3e-05
Identities = 22/57 (38%), Positives = 32/57 (56%), Gaps = 1/57 (1%)
Frame = +2
Query: 29 WKCDGENDCGNNFDESRCTETDNMCNNVKFNCK-DGKVIPRAYQCDKEADCVNGDDE 196
W+CDG DC ++ DE C C + F C +G IP ++ CD++ DC +G DE
Sbjct: 45 WRCDGTRDCLDDTDEIGCPPRS--CESGLFLCPAEGTCIPSSWVCDEDKDCSDGADE 99
Score = 47.0 bits (110), Expect = 4e-05
Identities = 20/58 (34%), Positives = 27/58 (46%)
Frame = +2
Query: 23 VHWKCDGENDCGNNFDESRCTETDNMCNNVKFNCKDGKVIPRAYQCDKEADCVNGDDE 196
+ WKCDG+ DC + DE C +F C+DG C+ DC +G DE
Sbjct: 3530 IWWKCDGQKDCSDGSDEPDLC-PHRFCRLGQFQCRDGNCTSPQALCNARQDCADGSDE 3586
Score = 46.2 bits (108), Expect = 6e-05
Identities = 17/54 (31%), Positives = 30/54 (55%)
Frame = +2
Query: 35 CDGENDCGNNFDESRCTETDNMCNNVKFNCKDGKVIPRAYQCDKEADCVNGDDE 196
C+ DC + DE R + C + ++ C + + IP+++QCD DC++ DE
Sbjct: 3574 CNARQDCADGSDEDRVLCEHHRCESNEWQCANKRCIPQSWQCDSVNDCLDNSDE 3627
Score = 45.1 bits (105), Expect = 1e-04
Identities = 27/71 (38%), Positives = 31/71 (43%), Gaps = 10/71 (14%)
Frame = +2
Query: 35 CDGENDCGNNFDESRCTE---TDNMCNNVKFNCKDGKVIPRAYQCDKEADCVNGDDE--- 196
CDG DC + DES C C F CK+ I + CD E DCV+G DE
Sbjct: 3819 CDGRADCLDASDESACPTRFPNGTYCPAAMFECKNHVCIQSFWICDGENDCVDGSDEEIH 3878
Query: 197 ----IGCVLPQ 217
I C PQ
Sbjct: 3879 LCFNIPCESPQ 3889
Score = 44.7 bits (104), Expect = 2e-04
Identities = 21/59 (35%), Positives = 28/59 (47%), Gaps = 2/59 (3%)
Frame = +2
Query: 35 CDGENDCGNNFDESR--CTETDNMCNNVKFNCKDGKVIPRAYQCDKEADCVNGDDEIGC 205
CD +NDCG+ DE C + C +F C +G I C+ DC + DE GC
Sbjct: 3053 CDEDNDCGDGSDEQEHLCHTPEPTCPLHQFRCDNGHCIEMGRVCNHVDDCSDNSDEKGC 3111
Score = 43.9 bits (102), Expect = 3e-04
Identities = 22/60 (36%), Positives = 31/60 (51%), Gaps = 1/60 (1%)
Frame = +2
Query: 29 WKCDGENDCGNNFDE-SRCTETDNMCNNVKFNCKDGKVIPRAYQCDKEADCVNGDDEIGC 205
W+CDG DC + DE + C C+ F C +G I +A+ CD + DC + DE C
Sbjct: 1249 WECDGHPDCIHGSDEHTGCVP--KTCSPTHFLCDNGNCIYKAWICDGDNDCRDMSDEKDC 1306
Score = 43.1 bits (100), Expect = 5e-04
Identities = 21/57 (36%), Positives = 27/57 (47%), Gaps = 1/57 (1%)
Frame = +2
Query: 29 WKCDGENDCGNNFDESRCTETDNMCNNVKFNCKD-GKVIPRAYQCDKEADCVNGDDE 196
W CDG+NDC + DE C C + ++ C I + CD DC NG DE
Sbjct: 1289 WICDGDNDCRDMSDEKDCPTQPFHCPSTQWQCPGYSTCINLSALCDGVFDCPNGTDE 1345
Score = 42.4 bits (98), Expect = 0.001
Identities = 21/60 (35%), Positives = 32/60 (53%), Gaps = 3/60 (5%)
Frame = +2
Query: 26 HWKCDGENDCGNNFDESRC--TETDNMCNNVKFNCK-DGKVIPRAYQCDKEADCVNGDDE 196
+W CDG++DC ++ DE C ++ + C ++ C G+ I CD DC GDDE
Sbjct: 238 NWVCDGDDDCQDSGDEDGCESNQSHHRCYpreWACPGSGRCISIDKVCDGVPDCPEGDDE 297
Score = 41.6 bits (96), Expect = 0.002
Identities = 21/59 (35%), Positives = 30/59 (50%), Gaps = 1/59 (1%)
Frame = +2
Query: 35 CDGENDCGNNFDESRCTETDNMCN-NVKFNCKDGKVIPRAYQCDKEADCVNGDDEIGCV 208
C+G +DC +N DE C C+ + F C + IP ++CD DC + DE CV
Sbjct: 3701 CNGFDDCRDNSDEQGCESVP--CHPSGDFRCANHHCIPLRWKCDGTDDCGDNSDEENCV 3757
Score = 41.2 bits (95), Expect = 0.002
Identities = 15/35 (42%), Positives = 22/35 (62%)
Frame = +2
Query: 101 CNNVKFNCKDGKVIPRAYQCDKEADCVNGDDEIGC 205
C + F C +G IP +++CD DC++ DEIGC
Sbjct: 28 CGSGNFRCDNGYCIPASWRCDGTRDCLDDTDEIGC 62
Score = 40.4 bits (93), Expect = 0.004
Identities = 17/48 (35%), Positives = 27/48 (56%), Gaps = 1/48 (2%)
Frame = +2
Query: 68 DESRCT-ETDNMCNNVKFNCKDGKVIPRAYQCDKEADCVNGDDEIGCV 208
D C +T CN ++F C +G I + ++CD + DC +G DE+ V
Sbjct: 2689 DNKYCVVDTGTRCNQLQFTCLNGHCINQDWKCDNDNDCGDGSDELPTV 2736
Score = 37.4 bits (85), Expect = 0.030
Identities = 17/59 (28%), Positives = 29/59 (49%)
Frame = +2
Query: 29 WKCDGENDCGNNFDESRCTETDNMCNNVKFNCKDGKVIPRAYQCDKEADCVNGDDEIGC 205
++CD +DC + DE C C+ + C +G + +CD++ DC + DE C
Sbjct: 125 YRCDHVSDCPDGSDERNCHYPT--CDQL--TCANGACYNTSQRCDQKVDCRDSSDEANC 179
Score = 36.6 bits (83), Expect = 0.051
Identities = 13/35 (37%), Positives = 20/35 (57%)
Frame = +2
Query: 101 CNNVKFNCKDGKVIPRAYQCDKEADCVNGDDEIGC 205
C ++ F C +GK +P ++CD DC + DE C
Sbjct: 1025 CGSLSFPCNNGKCVPSFFRCDGVDDCHDNSDEHQC 1059
Score = 32.7 bits (73), Expect = 0.74
Identities = 14/34 (41%), Positives = 22/34 (64%), Gaps = 1/34 (2%)
Frame = +2
Query: 98 MCNNVKFNCKDG-KVIPRAYQCDKEADCVNGDDE 196
MC++ +F C + K IP ++CD + DC +G DE
Sbjct: 3513 MCSSTQFLCGNNEKCIPIWWKCDGQKDCSDGSDE 3546
Score = 31.6 bits (70), Expect = 1.7
Identities = 12/24 (50%), Positives = 15/24 (62%)
Frame = +2
Query: 26 HWKCDGENDCGNNFDESRCTETDN 97
H+ CD NDCG+ DE+ C DN
Sbjct: 3946 HYVCDNVNDCGDLSDETGCNLGDN 3969
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 62,706,902
Number of Sequences: 369166
Number of extensions: 1124815
Number of successful extensions: 4559
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3070
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4059
length of database: 68,354,980
effective HSP length: 105
effective length of database: 48,957,805
effective search space used: 4748907085
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)