Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_009_I24
(458 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9D8Y8|ING5_MOUSE Inhibitor of growth protein 5 94 1e-19
sp|Q8WYH8|ING5_HUMAN Inhibitor of growth protein 5 (p28ING5) 93 3e-19
sp|Q9UNL4|ING4_HUMAN Inhibitor of growth protein 4 (p29ING4) 87 1e-17
sp|Q8C0D7|ING4_MOUSE Inhibitor of growth protein 4 87 1e-17
sp|Q9QXV3|ING1_MOUSE Inhibitor of growth protein 1 63 4e-10
sp|Q9UK53|ING1_HUMAN Inhibitor of growth protein 1 63 4e-10
sp|Q8VEK6|ING3_MOUSE Inhibitor of growth protein 3 (p47ING3... 59 4e-09
sp|Q9H160|ING2_HUMAN Inhibitor of growth protein 2 (p33ING2... 59 7e-09
sp|Q9ESK4|ING2_MOUSE Inhibitor of growth protein 2 (p33ING2... 59 7e-09
sp|Q9NXR8|ING3_HUMAN Inhibitor of growth protein 3 (p47ING3... 57 2e-08
>sp|Q9D8Y8|ING5_MOUSE Inhibitor of growth protein 5
Length = 240
Score = 94.4 bits (233), Expect = 1e-19
Identities = 56/180 (31%), Positives = 79/180 (43%), Gaps = 28/180 (15%)
Frame = +2
Query: 2 ELDKKIMDVTKKIQFLTXXXXXXXXXXSKSDHLNEVAKIERLFSQGRDMCNDKVSLAENI 181
ELD++ D +I L S + + + KI+ +S+ ++ +DKV LA
Sbjct: 30 ELDQRTEDKKAEIDILAAEYISTVKTLSSAQRVEHLQKIQSAYSKCKEYSDDKVQLAMQT 89
Query: 182 YEMIDKQIRSLDTDLQHYXXXXXXXXXXXXXXXYSMNTV--------------------- 298
YEM+DK IR LD DL + ++
Sbjct: 90 YEMVDKHIRRLDADLARFEADLKDRMDGSDFESTGARSLKKGRSQKEKRSSRGRGRRTSE 149
Query: 299 DDIPSMVA-------LTMALTDNKDEILDMPVDPNEPVYCLCHQVSFGEMVACDNKICPI 457
+D P L+ + ++LDMPVDPNEP YCLCHQVS+GEM+ CDN CPI
Sbjct: 150 EDTPKKKKHKSGSEFTDSILSVHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCPI 209
>sp|Q8WYH8|ING5_HUMAN Inhibitor of growth protein 5 (p28ING5)
Length = 240
Score = 92.8 bits (229), Expect = 3e-19
Identities = 56/180 (31%), Positives = 77/180 (42%), Gaps = 28/180 (15%)
Frame = +2
Query: 2 ELDKKIMDVTKKIQFLTXXXXXXXXXXSKSDHLNEVAKIERLFSQGRDMCNDKVSLAENI 181
ELD++ D +I L S + + KI+ +S+ ++ +DKV LA
Sbjct: 30 ELDQRTEDKKAEIDILAAEYISTVKTLSPDQRVERLQKIQNAYSKCKEYSDDKVQLAMQT 89
Query: 182 YEMIDKQIRSLDTDLQHYXXXXXXXXXXXXXXXYS---------------------MNTV 298
YEM+DK IR LD DL + +
Sbjct: 90 YEMVDKHIRRLDADLARFEADLKDKMEGSDFESSGGRGLKKGRGQKEKRGSRGRGRRTSE 149
Query: 299 DDIPSMVA-------LTMALTDNKDEILDMPVDPNEPVYCLCHQVSFGEMVACDNKICPI 457
+D P L+ + ++LDMPVDPNEP YCLCHQVS+GEM+ CDN CPI
Sbjct: 150 EDTPKKKKHKGGSEFTDTILSVHPSDVLDMPVDPNEPTYCLCHQVSYGEMIGCDNPDCPI 209
>sp|Q9UNL4|ING4_HUMAN Inhibitor of growth protein 4 (p29ING4)
Length = 249
Score = 87.4 bits (215), Expect = 1e-17
Identities = 56/190 (29%), Positives = 79/190 (41%), Gaps = 38/190 (20%)
Frame = +2
Query: 2 ELDKKIMDVTKKIQFLTXXXXXXXXXXSKSDHLNEVAKIERLFSQGRDMCNDKVSLAENI 181
+LD++ D+ +I L S + L + +I+ + + ++ +DKV LA
Sbjct: 30 DLDQRTEDLKAEIDKLATEYMSSARSLSSEEKLALLKQIQEAYGKCKEFGDDKVQLAMQT 89
Query: 182 YEMIDKQIRSLDTDLQHYXXXXXXXXXXXXXXXYSM-----------------------N 292
YEM+DK IR LDTDL + S N
Sbjct: 90 YEMVDKHIRRLDTDLARFEADLKEKQIESSDYDSSSSKGKKKGRTQKEKKAARARSKGKN 149
Query: 293 TVDDIPSMVALTMALTDNKDE---------------ILDMPVDPNEPVYCLCHQVSFGEM 427
+ ++ P + L E +LDMPVDPNEP YCLCHQVS+GEM
Sbjct: 150 SDEEAPKTAQKKLKLVRTSPEYGMPSVTFGSVHPSDVLDMPVDPNEPTYCLCHQVSYGEM 209
Query: 428 VACDNKICPI 457
+ CDN C I
Sbjct: 210 IGCDNPDCSI 219
>sp|Q8C0D7|ING4_MOUSE Inhibitor of growth protein 4
Length = 249
Score = 87.4 bits (215), Expect = 1e-17
Identities = 56/190 (29%), Positives = 79/190 (41%), Gaps = 38/190 (20%)
Frame = +2
Query: 2 ELDKKIMDVTKKIQFLTXXXXXXXXXXSKSDHLNEVAKIERLFSQGRDMCNDKVSLAENI 181
+LD++ D+ +I L S + L + +I+ + + ++ +DKV LA
Sbjct: 30 DLDQRTEDLKAEIDKLATEYMSSARSLSSEEKLALLRQIQEAYGKCKEFGDDKVQLAMQT 89
Query: 182 YEMIDKQIRSLDTDLQHYXXXXXXXXXXXXXXXYSM-----------------------N 292
YEM+DK IR LDTDL + S N
Sbjct: 90 YEMVDKHIRRLDTDLARFEADLKEKQIESSDYDSSSSKGKKKGRTQKEKKAARARSKGKN 149
Query: 293 TVDDIPSMVALTMALTDNKDE---------------ILDMPVDPNEPVYCLCHQVSFGEM 427
+ ++ P + L E +LDMPVDPNEP YCLCHQVS+GEM
Sbjct: 150 SDEEAPKAAQKKLKLVRTSPEYGMPSVTFGSVHPSDVLDMPVDPNEPTYCLCHQVSYGEM 209
Query: 428 VACDNKICPI 457
+ CDN C I
Sbjct: 210 IGCDNPDCSI 219
>sp|Q9QXV3|ING1_MOUSE Inhibitor of growth protein 1
Length = 279
Score = 62.8 bits (151), Expect = 4e-10
Identities = 23/32 (71%), Positives = 28/32 (87%)
Frame = +2
Query: 362 DMPVDPNEPVYCLCHQVSFGEMVACDNKICPI 457
D+P+DPNEP YCLC+QVS+GEM+ CDN CPI
Sbjct: 202 DLPIDPNEPTYCLCNQVSYGEMIGCDNDECPI 233
>sp|Q9UK53|ING1_HUMAN Inhibitor of growth protein 1
Length = 422
Score = 62.8 bits (151), Expect = 4e-10
Identities = 23/32 (71%), Positives = 28/32 (87%)
Frame = +2
Query: 362 DMPVDPNEPVYCLCHQVSFGEMVACDNKICPI 457
D+P+DPNEP YCLC+QVS+GEM+ CDN CPI
Sbjct: 345 DLPIDPNEPTYCLCNQVSYGEMIGCDNDECPI 376
>sp|Q8VEK6|ING3_MOUSE Inhibitor of growth protein 3 (p47ING3 protein)
Length = 421
Score = 59.3 bits (142), Expect = 4e-09
Identities = 28/58 (48%), Positives = 38/58 (65%)
Frame = +2
Query: 284 SMNTVDDIPSMVALTMALTDNKDEILDMPVDPNEPVYCLCHQVSFGEMVACDNKICPI 457
S +TV S A + +D+ ++ D DPNEP YC+C+QVS+GEMV CDN+ CPI
Sbjct: 330 SSSTVVQEVSQQATVVPESDSNSQV-DWTYDPNEPRYCICNQVSYGEMVGCDNQDCPI 386
>sp|Q9H160|ING2_HUMAN Inhibitor of growth protein 2 (p33ING2) (Inhibitor of growth 1-like
protein) (ING1Lp) (p32)
Length = 280
Score = 58.5 bits (140), Expect = 7e-09
Identities = 21/33 (63%), Positives = 28/33 (84%)
Frame = +2
Query: 359 LDMPVDPNEPVYCLCHQVSFGEMVACDNKICPI 457
++ +DPNEP YCLC+QVS+GEM+ CDN+ CPI
Sbjct: 203 VEFAIDPNEPTYCLCNQVSYGEMIGCDNEQCPI 235
>sp|Q9ESK4|ING2_MOUSE Inhibitor of growth protein 2 (p33ING2) (Inhibitor of growth 1-like
protein)
Length = 281
Score = 58.5 bits (140), Expect = 7e-09
Identities = 21/33 (63%), Positives = 28/33 (84%)
Frame = +2
Query: 359 LDMPVDPNEPVYCLCHQVSFGEMVACDNKICPI 457
++ +DPNEP YCLC+QVS+GEM+ CDN+ CPI
Sbjct: 204 VEFAIDPNEPTYCLCNQVSYGEMIGCDNEQCPI 236
>sp|Q9NXR8|ING3_HUMAN Inhibitor of growth protein 3 (p47ING3 protein)
Length = 418
Score = 57.4 bits (137), Expect = 2e-08
Identities = 27/58 (46%), Positives = 37/58 (63%)
Frame = +2
Query: 284 SMNTVDDIPSMVALTMALTDNKDEILDMPVDPNEPVYCLCHQVSFGEMVACDNKICPI 457
S +TV S + +D+ ++ D DPNEP YC+C+QVS+GEMV CDN+ CPI
Sbjct: 327 SSSTVVQEISQQTTVVPESDSNSQV-DWTYDPNEPRYCICNQVSYGEMVGCDNQDCPI 383
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 42,640,684
Number of Sequences: 369166
Number of extensions: 676468
Number of successful extensions: 1426
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 1407
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 1426
length of database: 68,354,980
effective HSP length: 101
effective length of database: 49,696,745
effective search space used: 2534533995
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)