Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_009_I21
(894 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|O43772|MCAT_HUMAN Mitochondrial carnitine/acylcarnitine ... 359 7e-99
sp|Q8HXY2|MCAT_MACFA Mitochondrial carnitine/acylcarnitine ... 357 3e-98
sp|Q9Z2Z6|MCAT_MOUSE Mitochondrial carnitine/acylcarnitine ... 352 8e-97
sp|P97521|MCAT_RAT Mitochondrial carnitine/acylcarnitine ca... 352 8e-97
sp|Q9VQG4|COLT_DROME Congested-like trachea protein 314 2e-85
sp|Q27257|DIF1_CAEEL Protein dif-1 306 7e-83
sp|Q93XM7|MCAT_ARATH Mitochondrial carnitine/acylcarnitine ... 187 3e-47
sp|Q9WVD5|ORNT1_MOUSE Mitochondrial ornithine transporter 1... 160 6e-39
sp|Q9Y619|ORNT1_HUMAN Mitochondrial ornithine transporter 1... 158 2e-38
sp|Q12289|CRC1_YEAST Mitochondrial carnitine carrier 155 1e-37
>sp|O43772|MCAT_HUMAN Mitochondrial carnitine/acylcarnitine carrier protein
(Carnitine/acylcarnitine translocase) (CAC)
Length = 301
Score = 359 bits (921), Expect = 7e-99
Identities = 175/267 (65%), Positives = 205/267 (76%)
Frame = +3
Query: 39 PLDTLKVRLQAMPIPKPGEPPVYKGLVDCFLQTLRNEGPVGFYKGMAAPLIGVTPMFAVC 218
PLDT+KVRLQ P PG+PP+Y G DCF +TL EG G Y+GMAAP+IGVTPMFAVC
Sbjct: 30 PLDTVKVRLQTQPPSLPGQPPMYSGTFDCFRKTLFREGITGLYRGMAAPIIGVTPMFAVC 89
Query: 219 FFGYNLGRKLQVKDENTPLTKPQIFAAGMLSGVFTTAIMTPGERIKCLLQVQGASKEPPK 398
FFG+ LG+KLQ K L+ PQ+FAAGMLSGVFTT IMTPGERIKCLLQ+Q +S E K
Sbjct: 90 FFGFGLGKKLQQKHPEDVLSYPQLFAAGMLSGVFTTGIMTPGERIKCLLQIQASSGES-K 148
Query: 399 YKGPGDVIRKLYKEGGIRSIYKGTAATLLRDIPATGTYFMSYEWLKEILTPEGGDKSHLS 578
Y G D +KLY+E GIR IYKGT TL+RD+PA+G YFM+YEWLK I TPEG S LS
Sbjct: 149 YTGTLDCAKKLYQEFGIRGIYKGTVLTLMRDVPASGMYFMTYEWLKNIFTPEGKRVSELS 208
Query: 579 PGRTLFAGGIAGMCNWLVCIPPDTLKSRLQTAPEGKYPHGLRSVFREMMANEGIVGLYRG 758
R L AGGIAG+ NW V IPPD LKSR QTAP GKYP+G R V RE++ +EG+ LY+G
Sbjct: 209 APRILVAGGIAGIFNWAVAIPPDVLKSRFQTAPPGKYPNGFRDVLRELIRDEGVTSLYKG 268
Query: 759 VSPVLIRAFPANAACFLGYEVSLKLLN 839
+ V+IRAFPANAACFLG+EV++K LN
Sbjct: 269 FNAVMIRAFPANAACFLGFEVAMKFLN 295
Score = 68.2 bits (165), Expect = 3e-11
Identities = 57/205 (27%), Positives = 90/205 (43%), Gaps = 5/205 (2%)
Frame = +3
Query: 258 DENTPLTKPQIFAAGMLSGVFTTAIMTPGERIKCLLQVQGASK--EPPKYKGPGDVIRKL 431
D+ P++ + AG GV + P + +K LQ Q S +PP Y G D RK
Sbjct: 3 DQPKPISPLKNLLAGGFGGVCLVFVGHPLDTVKVRLQTQPPSLPGQPPMYSGTFDCFRKT 62
Query: 432 YKEGGIRSIYKGTAATLLRDIPATGTYFMSYEWLKEILTPEGGDKSHLSPGRTLFAGGIA 611
GI +Y+G AA ++ P F + K++ D LS + AG ++
Sbjct: 63 LFREGITGLYRGMAAPIIGVTPMFAVCFFGFGLGKKLQQKHPEDV--LSYPQLFAAGMLS 120
Query: 612 GMCNWLVCIPPDTLKSRLQ---TAPEGKYPHGLRSVFREMMANEGIVGLYRGVSPVLIRA 782
G+ + P + +K LQ ++ E KY G +++ GI G+Y+G L+R
Sbjct: 121 GVFTTGIMTPGERIKCLLQIQASSGESKYT-GTLDCAKKLYQEFGIRGIYKGTVLTLMRD 179
Query: 783 FPANAACFLGYEVSLKLLNKVFKRV 857
PA+ F+ YE + KRV
Sbjct: 180 VPASGMYFMTYEWLKNIFTPEGKRV 204
>sp|Q8HXY2|MCAT_MACFA Mitochondrial carnitine/acylcarnitine carrier protein
(Carnitine/acylcarnitine translocase) (CAC)
Length = 301
Score = 357 bits (915), Expect = 3e-98
Identities = 173/267 (64%), Positives = 205/267 (76%)
Frame = +3
Query: 39 PLDTLKVRLQAMPIPKPGEPPVYKGLVDCFLQTLRNEGPVGFYKGMAAPLIGVTPMFAVC 218
PLDT+KVRLQ P PG+PP+Y G DCF +TL EG G Y+GMAAP+IGVTPMFAVC
Sbjct: 30 PLDTVKVRLQTQPPSLPGQPPMYSGTFDCFRKTLFREGIRGLYRGMAAPIIGVTPMFAVC 89
Query: 219 FFGYNLGRKLQVKDENTPLTKPQIFAAGMLSGVFTTAIMTPGERIKCLLQVQGASKEPPK 398
FFG+ LG+KLQ K L+ PQ+FAAGMLSG+FTT IMTPGERIKCLLQ+Q +S E K
Sbjct: 90 FFGFGLGKKLQQKHPEDVLSYPQLFAAGMLSGIFTTGIMTPGERIKCLLQIQASSGET-K 148
Query: 399 YKGPGDVIRKLYKEGGIRSIYKGTAATLLRDIPATGTYFMSYEWLKEILTPEGGDKSHLS 578
Y G D +KLY+E GIR IYKGT TL+RD+PA+G YFM+YEW+K I TPEG S LS
Sbjct: 149 YTGTLDCAKKLYQEFGIRGIYKGTVVTLMRDVPASGMYFMTYEWVKNIFTPEGKRVSELS 208
Query: 579 PGRTLFAGGIAGMCNWLVCIPPDTLKSRLQTAPEGKYPHGLRSVFREMMANEGIVGLYRG 758
R L AGGIAG+ NW V IPPD LKSR QTAP GKYP+G R V RE++ +EG+ LY+G
Sbjct: 209 VPRVLVAGGIAGIFNWAVAIPPDVLKSRFQTAPPGKYPNGFRDVLRELIPDEGVTSLYKG 268
Query: 759 VSPVLIRAFPANAACFLGYEVSLKLLN 839
+ V+IRAFPANAACFLG+EV++K LN
Sbjct: 269 FNAVMIRAFPANAACFLGFEVAMKFLN 295
Score = 70.1 bits (170), Expect = 8e-12
Identities = 58/205 (28%), Positives = 91/205 (44%), Gaps = 5/205 (2%)
Frame = +3
Query: 258 DENTPLTKPQIFAAGMLSGVFTTAIMTPGERIKCLLQVQGASK--EPPKYKGPGDVIRKL 431
D+ P++ + AG GV + P + +K LQ Q S +PP Y G D RK
Sbjct: 3 DQPKPISPLKNLLAGGFGGVCLVFVGHPLDTVKVRLQTQPPSLPGQPPMYSGTFDCFRKT 62
Query: 432 YKEGGIRSIYKGTAATLLRDIPATGTYFMSYEWLKEILTPEGGDKSHLSPGRTLFAGGIA 611
GIR +Y+G AA ++ P F + K++ D LS + AG ++
Sbjct: 63 LFREGIRGLYRGMAAPIIGVTPMFAVCFFGFGLGKKLQQKHPEDV--LSYPQLFAAGMLS 120
Query: 612 GMCNWLVCIPPDTLKSRLQ---TAPEGKYPHGLRSVFREMMANEGIVGLYRGVSPVLIRA 782
G+ + P + +K LQ ++ E KY G +++ GI G+Y+G L+R
Sbjct: 121 GIFTTGIMTPGERIKCLLQIQASSGETKYT-GTLDCAKKLYQEFGIRGIYKGTVVTLMRD 179
Query: 783 FPANAACFLGYEVSLKLLNKVFKRV 857
PA+ F+ YE + KRV
Sbjct: 180 VPASGMYFMTYEWVKNIFTPEGKRV 204
>sp|Q9Z2Z6|MCAT_MOUSE Mitochondrial carnitine/acylcarnitine carrier protein
(Carnitine/acylcarnitine translocase) (CAC) (mCAC)
Length = 301
Score = 352 bits (903), Expect = 8e-97
Identities = 169/267 (63%), Positives = 201/267 (75%)
Frame = +3
Query: 39 PLDTLKVRLQAMPIPKPGEPPVYKGLVDCFLQTLRNEGPVGFYKGMAAPLIGVTPMFAVC 218
PLDT+KVRLQ P G+PP+Y G +DCF +TL EG G Y+GMAAP+IGVTPMFAVC
Sbjct: 30 PLDTVKVRLQTQPPSLSGQPPMYSGTLDCFRKTLMREGITGLYRGMAAPIIGVTPMFAVC 89
Query: 219 FFGYNLGRKLQVKDENTPLTKPQIFAAGMLSGVFTTAIMTPGERIKCLLQVQGASKEPPK 398
FFG+ LG+KLQ K L+ PQ+F AGMLSGVFTT IMTPGERIKCLLQ+Q +S E K
Sbjct: 90 FFGFGLGKKLQQKSPEDELSYPQLFTAGMLSGVFTTGIMTPGERIKCLLQIQASSGEN-K 148
Query: 399 YKGPGDVIRKLYKEGGIRSIYKGTAATLLRDIPATGTYFMSYEWLKEILTPEGGDKSHLS 578
Y G D +KLY+E GIR YKGT TL+RD+PA+G YFM+YEWLK + TPEG S LS
Sbjct: 149 YSGTLDCAKKLYQEFGIRGFYKGTVLTLMRDVPASGMYFMTYEWLKNLFTPEGKSVSDLS 208
Query: 579 PGRTLFAGGIAGMCNWLVCIPPDTLKSRLQTAPEGKYPHGLRSVFREMMANEGIVGLYRG 758
R L AGG AG+ NW V IPPD LKSR QTAP GKYP+G R V RE++ EG+ LY+G
Sbjct: 209 VPRILVAGGFAGIFNWAVAIPPDVLKSRFQTAPPGKYPNGFRDVLRELIREEGVTSLYKG 268
Query: 759 VSPVLIRAFPANAACFLGYEVSLKLLN 839
+ V+IRAFPANAACFLG+E+++K LN
Sbjct: 269 FNAVMIRAFPANAACFLGFEIAMKFLN 295
Score = 69.7 bits (169), Expect = 1e-11
Identities = 41/95 (43%), Positives = 52/95 (54%), Gaps = 5/95 (5%)
Frame = +3
Query: 573 LSPGRTLFAGGIAGMCNWLVCIPPDTLKSRLQTAP---EGKYP--HGLRSVFREMMANEG 737
+SP + L AGG GMC V P DT+K RLQT P G+ P G FR+ + EG
Sbjct: 8 ISPFKNLLAGGFGGMCLVFVGHPLDTVKVRLQTQPPSLSGQPPMYSGTLDCFRKTLMREG 67
Query: 738 IVGLYRGVSPVLIRAFPANAACFLGYEVSLKLLNK 842
I GLYRG++ +I P A CF G+ + KL K
Sbjct: 68 ITGLYRGMAAPIIGVTPMFAVCFFGFGLGKKLQQK 102
>sp|P97521|MCAT_RAT Mitochondrial carnitine/acylcarnitine carrier protein
(Carnitine/acylcarnitine translocase) (CAC)
Length = 301
Score = 352 bits (903), Expect = 8e-97
Identities = 168/267 (62%), Positives = 201/267 (75%)
Frame = +3
Query: 39 PLDTLKVRLQAMPIPKPGEPPVYKGLVDCFLQTLRNEGPVGFYKGMAAPLIGVTPMFAVC 218
PLDT+KVRLQ P PG+PP+Y G +DCF +TL EG G Y+GMAAP+IGVTPMFAVC
Sbjct: 30 PLDTVKVRLQTQPPSLPGQPPMYSGTIDCFRKTLFREGITGLYRGMAAPIIGVTPMFAVC 89
Query: 219 FFGYNLGRKLQVKDENTPLTKPQIFAAGMLSGVFTTAIMTPGERIKCLLQVQGASKEPPK 398
FFG+ LG++LQ K LT PQ+F AGMLSGVFTT IMTPGERIKCLLQ+Q AS K
Sbjct: 90 FFGFGLGKRLQQKSPEDELTYPQLFTAGMLSGVFTTGIMTPGERIKCLLQIQ-ASSGKNK 148
Query: 399 YKGPGDVIRKLYKEGGIRSIYKGTAATLLRDIPATGTYFMSYEWLKEILTPEGGDKSHLS 578
Y G D +KLY+E GIR YKGTA TL+RD+PA+G YFM+YEWLK + TP+G LS
Sbjct: 149 YSGTLDCAKKLYQEFGIRGFYKGTALTLMRDVPASGMYFMTYEWLKNLFTPQGKSVHDLS 208
Query: 579 PGRTLFAGGIAGMCNWLVCIPPDTLKSRLQTAPEGKYPHGLRSVFREMMANEGIVGLYRG 758
R L AGG G+ NW+V IPPD LKSR QTAP GKYP+G R V RE++ EG+ LY+G
Sbjct: 209 VPRVLVAGGFRGIFNWVVAIPPDVLKSRFQTAPPGKYPNGFRDVLRELIREEGVTSLYKG 268
Query: 759 VSPVLIRAFPANAACFLGYEVSLKLLN 839
+ V+IRAFPANAACFLG+E+ +K+LN
Sbjct: 269 FNAVMIRAFPANAACFLGFEIPMKILN 295
Score = 65.5 bits (158), Expect = 2e-10
Identities = 39/95 (41%), Positives = 52/95 (54%), Gaps = 5/95 (5%)
Frame = +3
Query: 573 LSPGRTLFAGGIAGMCNWLVCIPPDTLKSRLQTAPE---GKYP--HGLRSVFREMMANEG 737
+SP + L AGG G+C V P DT+K RLQT P G+ P G FR+ + EG
Sbjct: 8 ISPLKNLLAGGFGGVCLVFVGHPLDTVKVRLQTQPPSLPGQPPMYSGTIDCFRKTLFREG 67
Query: 738 IVGLYRGVSPVLIRAFPANAACFLGYEVSLKLLNK 842
I GLYRG++ +I P A CF G+ + +L K
Sbjct: 68 ITGLYRGMAAPIIGVTPMFAVCFFGFGLGKRLQQK 102
>sp|Q9VQG4|COLT_DROME Congested-like trachea protein
Length = 306
Score = 314 bits (804), Expect = 2e-85
Identities = 149/269 (55%), Positives = 196/269 (72%)
Frame = +3
Query: 39 PLDTLKVRLQAMPIPKPGEPPVYKGLVDCFLQTLRNEGPVGFYKGMAAPLIGVTPMFAVC 218
PLDT+KVRLQ MP P PGE P+Y+G DC +T++NEG G YKGM+APL GV P+FA+C
Sbjct: 35 PLDTIKVRLQTMPRPAPGEQPLYRGTFDCAAKTIKNEGVRGLYKGMSAPLTGVAPIFAMC 94
Query: 219 FFGYNLGRKLQVKDENTPLTKPQIFAAGMLSGVFTTAIMTPGERIKCLLQVQGASKEPPK 398
F GY LG++LQ + E+ LT PQIF AG SG+F+T IM PGERIK LLQ Q K
Sbjct: 95 FAGYALGKRLQQRGEDAKLTYPQIFVAGSFSGLFSTLIMAPGERIKVLLQTQQGQGGERK 154
Query: 399 YKGPGDVIRKLYKEGGIRSIYKGTAATLLRDIPATGTYFMSYEWLKEILTPEGGDKSHLS 578
Y G D KLYKEGG+RS++KG+ AT+LRD+PA G YF+ YE L+++ + + +S
Sbjct: 155 YNGMIDCAGKLYKEGGLRSVFKGSCATMLRDLPANGLYFLVYEALQDVAKSK-SETGQIS 213
Query: 579 PGRTLFAGGIAGMCNWLVCIPPDTLKSRLQTAPEGKYPHGLRSVFREMMANEGIVGLYRG 758
T+FAGG+AGM W++ +P D LKSRLQ+APEG Y HG+RSVF++++ +G + LYRG
Sbjct: 214 TASTIFAGGVAGMAYWILGMPADVLKSRLQSAPEGTYKHGIRSVFKDLIVKDGPLALYRG 273
Query: 759 VSPVLIRAFPANAACFLGYEVSLKLLNKV 845
V+P+++RAFPANAACF G E++ K N V
Sbjct: 274 VTPIMLRAFPANAACFFGIELANKFFNIV 302
Score = 60.1 bits (144), Expect = 8e-09
Identities = 35/91 (38%), Positives = 48/91 (52%), Gaps = 5/91 (5%)
Frame = +3
Query: 576 SPGRTLFAGGIAGMCNWLVCIPPDTLKSRLQTAPE---GKYP--HGLRSVFREMMANEGI 740
+P ++ GG G+CN L P DT+K RLQT P G+ P G + + NEG+
Sbjct: 14 NPVKSFLTGGFGGICNVLSGHPLDTIKVRLQTMPRPAPGEQPLYRGTFDCAAKTIKNEGV 73
Query: 741 VGLYRGVSPVLIRAFPANAACFLGYEVSLKL 833
GLY+G+S L P A CF GY + +L
Sbjct: 74 RGLYKGMSAPLTGVAPIFAMCFAGYALGKRL 104
>sp|Q27257|DIF1_CAEEL Protein dif-1
Length = 312
Score = 306 bits (783), Expect = 7e-83
Identities = 154/265 (58%), Positives = 193/265 (72%), Gaps = 2/265 (0%)
Frame = +3
Query: 39 PLDTLKVRLQAMPIPKPGEPPVYKGLVDCFLQTLRNEGPVGFYKGMAAPLIGVTPMFAVC 218
P DT+KVR+Q MP+PKPGE P + G +DC +T+ EG YKGMAAPL+GV+P+FAV
Sbjct: 24 PFDTVKVRIQTMPMPKPGEKPQFTGALDCVKRTVSKEGFFALYKGMAAPLVGVSPLFAVF 83
Query: 219 FFGYNLGRKLQVKDENTPLTKPQIFAAGMLSGVFTTAIMTPGERIKCLLQVQ--GASKEP 392
F G +G+ LQ D + +T Q AG L+GVFTT +M PGERIKCLLQVQ G++
Sbjct: 84 FGGCAVGKWLQQTDPSQEMTFIQNANAGALAGVFTTIVMVPGERIKCLLQVQQAGSAGSG 143
Query: 393 PKYKGPGDVIRKLYKEGGIRSIYKGTAATLLRDIPATGTYFMSYEWLKEILTPEGGDKSH 572
Y GP DV++KLYK+GGI SIY+GT ATLLRDIPA+ Y YE+LK+ + EG ++
Sbjct: 144 VHYDGPLDVVKKLYKQGGISSIYRGTGATLLRDIPASAAYLSVYEYLKKKFSGEGAQRT- 202
Query: 573 LSPGRTLFAGGIAGMCNWLVCIPPDTLKSRLQTAPEGKYPHGLRSVFREMMANEGIVGLY 752
LSPG TL AGG+AG+ NW VCIP D LKSRLQTAPEGKYP G+R V RE++ EG L+
Sbjct: 203 LSPGATLMAGGLAGIANWGVCIPADVLKSRLQTAPEGKYPDGIRGVLREVLREEGPRALF 262
Query: 753 RGVSPVLIRAFPANAACFLGYEVSL 827
+G PV++RAFPANAACF G E++L
Sbjct: 263 KGFWPVMLRAFPANAACFFGLELTL 287
Score = 44.7 bits (104), Expect = 4e-04
Identities = 28/80 (35%), Positives = 40/80 (50%), Gaps = 5/80 (6%)
Frame = +3
Query: 597 AGGIAGMCNWLVCIPPDTLKSRLQTAP---EGKYPH--GLRSVFREMMANEGIVGLYRGV 761
AGG+ G C +V P DT+K R+QT P G+ P G + ++ EG LY+G+
Sbjct: 10 AGGVGGSCTVIVGHPFDTVKVRIQTMPMPKPGEKPQFTGALDCVKRTVSKEGFFALYKGM 69
Query: 762 SPVLIRAFPANAACFLGYEV 821
+ L+ P A F G V
Sbjct: 70 AAPLVGVSPLFAVFFGGCAV 89
>sp|Q93XM7|MCAT_ARATH Mitochondrial carnitine/acylcarnitine carrier-like protein (A BOUT
DE SOUFFLE) (Carnitine/acylcarnitine translocase-like
protein) (CAC-like protein)
Length = 300
Score = 187 bits (476), Expect = 3e-47
Identities = 113/274 (41%), Positives = 144/274 (52%), Gaps = 12/274 (4%)
Frame = +3
Query: 39 PLDTLKVRLQAMPIPKPGEPPVYKGLVDCFLQTLRNEGPVGFYKGMAAPLIGVTPMFAVC 218
P DT+KV+LQ+ P P PG+ P Y G +D QT+ +EG G YKGM APL V AV
Sbjct: 24 PFDTIKVKLQSQPTPAPGQLPRYTGAIDAVKQTVASEGTKGLYKGMGAPLATVAAFNAVL 83
Query: 219 FFGYNLGRKLQVKDENTPLTKPQIFAAGMLSGVFTTAIMTPGERIKCLLQVQGASK---- 386
F L + PLT Q F AG +G + + P E IKC LQ QGA
Sbjct: 84 FTVRGQMEGLLRSEAGVPLTISQQFVAGAGAGFAVSFLACPTELIKCRLQAQGALAGAST 143
Query: 387 -----EPPKYKGPGDVIRK-LYKEGGIRSIYKGTAATLLRDIPATGTYFMSYEWLKEILT 548
KY GP DV R L EGG R ++KG T R++P T F +YE K L
Sbjct: 144 TSSVVAAVKYGGPMDVARHVLRSEGGARGLFKGLFPTFAREVPGNATMFAAYEAFKRFLA 203
Query: 549 PEGGDKSHLSPGRTLFAGGIAGMCNWLVCIPPDTLKSRLQTAPEGKYPH--GLRSVFREM 722
G D S L G + AGG+AG W + P D +KS LQ + K P G FR++
Sbjct: 204 -GGSDTSSLGQGSLIMAGGVAGASFWGIVYPTDVVKSVLQ-VDDYKNPRYTGSMDAFRKI 261
Query: 723 MANEGIVGLYRGVSPVLIRAFPANAACFLGYEVS 824
+ +EG+ GLY+G P + R+ PANAACFL YE++
Sbjct: 262 LKSEGVKGLYKGFGPAMARSVPANAACFLAYEMT 295
Score = 67.0 bits (162), Expect = 7e-11
Identities = 43/149 (28%), Positives = 68/149 (45%), Gaps = 2/149 (1%)
Frame = +3
Query: 105 YKGLVDCFLQTLRNEGPV-GFYKGMAAPLIGVTPMFAVCFFGYNLGRKLQVKDENTP-LT 278
Y G +D LR+EG G +KG+ P A F Y ++ +T L
Sbjct: 153 YGGPMDVARHVLRSEGGARGLFKGLFPTFAREVPGNATMFAAYEAFKRFLAGGSDTSSLG 212
Query: 279 KPQIFAAGMLSGVFTTAIMTPGERIKCLLQVQGASKEPPKYKGPGDVIRKLYKEGGIRSI 458
+ + AG ++G I+ P + +K +LQV P+Y G D RK+ K G++ +
Sbjct: 213 QGSLIMAGGVAGASFWGIVYPTDVVKSVLQVDDYKN--PRYTGSMDAFRKILKSEGVKGL 270
Query: 459 YKGTAATLLRDIPATGTYFMSYEWLKEIL 545
YKG + R +PA F++YE + L
Sbjct: 271 YKGFGPAMARSVPANAACFLAYEMTRSSL 299
Score = 58.2 bits (139), Expect = 3e-08
Identities = 53/197 (26%), Positives = 79/197 (40%), Gaps = 16/197 (8%)
Frame = +3
Query: 294 AAGMLSGVFTTAIMTPGERIKCLLQVQG--ASKEPPKYKGPGDVIRKLYKEGGIRSIYKG 467
A+G + G + P + IK LQ Q A + P+Y G D +++ G + +YKG
Sbjct: 9 ASGTVGGAAQLVVGHPFDTIKVKLQSQPTPAPGQLPRYTGAIDAVKQTVASEGTKGLYKG 68
Query: 468 TAATLLRDIPATGTYFMSYEWLKEILTPEGGDKSHLSPGRTLFAGGIAGMCNWLVCIPPD 647
A L F ++ +L E G +S + AG AG + P +
Sbjct: 69 MGAPLATVAAFNAVLFTVRGQMEGLLRSEAGVPLTIS--QQFVAGAGAGFAVSFLACPTE 126
Query: 648 TLKSRLQT-------------APEGKYPHGLRSVFREMMANEGIV-GLYRGVSPVLIRAF 785
+K RLQ KY G V R ++ +EG GL++G+ P R
Sbjct: 127 LIKCRLQAQGALAGASTTSSVVAAVKYG-GPMDVARHVLRSEGGARGLFKGLFPTFAREV 185
Query: 786 PANAACFLGYEVSLKLL 836
P NA F YE + L
Sbjct: 186 PGNATMFAAYEAFKRFL 202
Score = 40.8 bits (94), Expect = 0.005
Identities = 23/68 (33%), Positives = 30/68 (44%)
Frame = +3
Query: 39 PLDTLKVRLQAMPIPKPGEPPVYKGLVDCFLQTLRNEGPVGFYKGMAAPLIGVTPMFAVC 218
P D +K LQ P Y G +D F + L++EG G YKG + P A C
Sbjct: 233 PTDVVKSVLQVDDYKNPR----YTGSMDAFRKILKSEGVKGLYKGFGPAMARSVPANAAC 288
Query: 219 FFGYNLGR 242
F Y + R
Sbjct: 289 FLAYEMTR 296
>sp|Q9WVD5|ORNT1_MOUSE Mitochondrial ornithine transporter 1 (Solute carrier family 25
member 15)
Length = 301
Score = 160 bits (404), Expect = 6e-39
Identities = 97/275 (35%), Positives = 138/275 (50%), Gaps = 8/275 (2%)
Frame = +3
Query: 36 QPLDTLKVRLQAMPIPKPGEPPVYKGLVDCFLQTLRNEGPVGFYKGMAAPLIGVTPMFAV 215
QP DT+KV++Q P +Y+GL DC L+T G GFYKG + LI +V
Sbjct: 28 QPFDTMKVKMQTFP-------DLYRGLTDCCLKTYSQVGFRGFYKGTSPALIANIAENSV 80
Query: 216 CFFGYN----LGRKLQVKDENTPLTKPQIFAAGMLSGVFTTAIMTPGERIKCLLQ----V 371
F Y + RK+ D+ L+ Q AAG + F ++ P E +KC LQ +
Sbjct: 81 LFMCYGFCQQVVRKVVGLDQQAKLSDLQNAAAGSFASAFAALVLCPTELVKCRLQTMYEM 140
Query: 372 QGASKEPPKYKGPGDVIRKLYKEGGIRSIYKGTAATLLRDIPATGTYFMSYEWLKEILTP 551
+ + K V+++++++ G Y G ++TLLR++P +F YE L
Sbjct: 141 ETSGKIAASQNTVWSVVKEIFRKDGPLGFYHGLSSTLLREVPGYFFFFGGYE-LSRSFFA 199
Query: 552 EGGDKSHLSPGRTLFAGGIAGMCNWLVCIPPDTLKSRLQTAPEGKYPHGLRSVFREMMAN 731
G K L P + +GG G+C WL P D +KSR+Q GL F ++ N
Sbjct: 200 SGRSKDELGPVPLMLSGGFGGICLWLAVYPVDCIKSRIQVLSMTGKQTGLVRTFLSIVKN 259
Query: 732 EGIVGLYRGVSPVLIRAFPANAACFLGYEVSLKLL 836
EGI LY G+ P +IRAFPAN A FL YE S KL+
Sbjct: 260 EGITALYSGLKPTMIRAFPANGALFLAYEYSRKLM 294
Score = 41.2 bits (95), Expect = 0.004
Identities = 27/85 (31%), Positives = 39/85 (45%)
Frame = +3
Query: 591 LFAGGIAGMCNWLVCIPPDTLKSRLQTAPEGKYPHGLRSVFREMMANEGIVGLYRGVSPV 770
L AG G L P DT+K ++QT P+ GL + + G G Y+G SP
Sbjct: 13 LTAGAAGGTACVLTGQPFDTMKVKMQTFPD--LYRGLTDCCLKTYSQVGFRGFYKGTSPA 70
Query: 771 LIRAFPANAACFLGYEVSLKLLNKV 845
LI N+ F+ Y +++ KV
Sbjct: 71 LIANIAENSVLFMCYGFCQQVVRKV 95
Score = 39.3 bits (90), Expect = 0.015
Identities = 22/72 (30%), Positives = 32/72 (44%)
Frame = +3
Query: 39 PLDTLKVRLQAMPIPKPGEPPVYKGLVDCFLQTLRNEGPVGFYKGMAAPLIGVTPMFAVC 218
P+D +K R+Q + + GLV FL ++NEG Y G+ +I P
Sbjct: 229 PVDCIKSRIQVLSMTGK-----QTGLVRTFLSIVKNEGITALYSGLKPTMIRAFPANGAL 283
Query: 219 FFGYNLGRKLQV 254
F Y RKL +
Sbjct: 284 FLAYEYSRKLMM 295
>sp|Q9Y619|ORNT1_HUMAN Mitochondrial ornithine transporter 1 (Solute carrier family 25,
member 15)
Length = 301
Score = 158 bits (400), Expect = 2e-38
Identities = 97/275 (35%), Positives = 136/275 (49%), Gaps = 8/275 (2%)
Frame = +3
Query: 36 QPLDTLKVRLQAMPIPKPGEPPVYKGLVDCFLQTLRNEGPVGFYKGMAAPLIGVTPMFAV 215
QP DT+KV++Q P +Y+GL DC L+T G GFYKG + LI +V
Sbjct: 28 QPFDTMKVKMQTFP-------DLYRGLTDCCLKTYSQVGFRGFYKGTSPALIANIAENSV 80
Query: 216 CFFGYN----LGRKLQVKDENTPLTKPQIFAAGMLSGVFTTAIMTPGERIKCLLQ----V 371
F Y + RK+ D+ L+ Q AAG + F ++ P E +KC LQ +
Sbjct: 81 LFMCYGFCQQVVRKVAGLDKQAKLSDLQNAAAGSFASAFAALVLCPTELVKCRLQTMYEM 140
Query: 372 QGASKEPPKYKGPGDVIRKLYKEGGIRSIYKGTAATLLRDIPATGTYFMSYEWLKEILTP 551
+ + K VI+ + ++ G Y G ++TLLR++P +F YE L
Sbjct: 141 ETSGKIAKSQNTVWSVIKSILRKDGPLGFYHGLSSTLLREVPGYFFFFGGYE-LSRSFFA 199
Query: 552 EGGDKSHLSPGRTLFAGGIAGMCNWLVCIPPDTLKSRLQTAPEGKYPHGLRSVFREMMAN 731
G K L P + +GG+ G+C WL P D +KSR+Q G F ++ N
Sbjct: 200 SGRSKDELGPVPLMLSGGVGGICLWLAVYPVDCIKSRIQVLSMSGKQAGFIRTFINVVKN 259
Query: 732 EGIVGLYRGVSPVLIRAFPANAACFLGYEVSLKLL 836
EGI LY G+ P +IRAFPAN A FL YE S KL+
Sbjct: 260 EGITALYSGLKPTMIRAFPANGALFLAYEYSRKLM 294
Score = 41.2 bits (95), Expect = 0.004
Identities = 27/85 (31%), Positives = 39/85 (45%)
Frame = +3
Query: 591 LFAGGIAGMCNWLVCIPPDTLKSRLQTAPEGKYPHGLRSVFREMMANEGIVGLYRGVSPV 770
L AG G L P DT+K ++QT P+ GL + + G G Y+G SP
Sbjct: 13 LTAGAAGGTACVLTGQPFDTMKVKMQTFPD--LYRGLTDCCLKTYSQVGFRGFYKGTSPA 70
Query: 771 LIRAFPANAACFLGYEVSLKLLNKV 845
LI N+ F+ Y +++ KV
Sbjct: 71 LIANIAENSVLFMCYGFCQQVVRKV 95
Score = 37.0 bits (84), Expect = 0.074
Identities = 19/72 (26%), Positives = 31/72 (43%)
Frame = +3
Query: 39 PLDTLKVRLQAMPIPKPGEPPVYKGLVDCFLQTLRNEGPVGFYKGMAAPLIGVTPMFAVC 218
P+D +K R+Q + + G + F+ ++NEG Y G+ +I P
Sbjct: 229 PVDCIKSRIQVLSMSGK-----QAGFIRTFINVVKNEGITALYSGLKPTMIRAFPANGAL 283
Query: 219 FFGYNLGRKLQV 254
F Y RKL +
Sbjct: 284 FLAYEYSRKLMM 295
>sp|Q12289|CRC1_YEAST Mitochondrial carnitine carrier
Length = 327
Score = 155 bits (392), Expect = 1e-37
Identities = 97/247 (39%), Positives = 136/247 (55%), Gaps = 11/247 (4%)
Frame = +3
Query: 135 TLRNEGPVGFYKGMAAPLIGVTPMFAVCFFGYNLGRKL----QVKDENTPLTKPQIFAAG 302
TL GFYKG+ PL+GVTP+FAV F+GY++G+KL + + LT Q+ AAG
Sbjct: 89 TLFTNSVKGFYKGVIPPLLGVTPIFAVSFWGYDVGKKLVTFNNKQGGSNELTMGQMAAAG 148
Query: 303 MLSGVFTTAIMTPGERIKCLLQVQGASKEPPKYKGPG-DVIRKLYKEGGIRSIYKGTAAT 479
+S + TT + P ER+K +LQ KG + + KEGGI S++KG+ AT
Sbjct: 149 FISAIPTTLVTAPTERVKVVLQTSS--------KGSFIQAAKTIVKEGGIASLFKGSLAT 200
Query: 480 LLRDIPATGTYFMSYEWLKEILT-----PEGGDKSHLSPGRTLFAGGIAGMCNWLVCIPP 644
L RD P + YF SYE K L + G ++ AGGIAGM WL P
Sbjct: 201 LARDGPGSALYFASYEISKNYLNSRQPRQDAGKDEPVNILNVCLAGGIAGMSMWLAVFPI 260
Query: 645 DTLKSRLQTAPEGKYPHGLRSVFREM-MANEGIVGLYRGVSPVLIRAFPANAACFLGYEV 821
DT+K++LQ + + + S +E+ + GI G + G+ P L+R+FPANAA FLG E+
Sbjct: 261 DTIKTKLQASSTRQ---NMLSATKEIYLQRGGIKGFFPGLGPALLRSFPANAATFLGVEM 317
Query: 822 SLKLLNK 842
+ L K
Sbjct: 318 THSLFKK 324
Score = 47.4 bits (111), Expect = 6e-05
Identities = 26/91 (28%), Positives = 41/91 (45%), Gaps = 7/91 (7%)
Frame = +3
Query: 585 RTLFAGGIAGMCNWLVCIPPDTLKSRLQTAPEGKYPHGLRSVFRE-------MMANEGIV 743
++ AGG+ G+C P D +K R Q H + ++ +E + +
Sbjct: 37 KSFVAGGVGGVCAVFTGHPFDLIKVRCQNGQANSTVHAITNIIKEAKTQVKGTLFTNSVK 96
Query: 744 GLYRGVSPVLIRAFPANAACFLGYEVSLKLL 836
G Y+GV P L+ P A F GY+V KL+
Sbjct: 97 GFYKGVIPPLLGVTPIFAVSFWGYDVGKKLV 127
Score = 37.4 bits (85), Expect = 0.057
Identities = 34/151 (22%), Positives = 59/151 (39%), Gaps = 9/151 (5%)
Frame = +3
Query: 132 QTLRNEGPVG-FYKGMAAPLIGVTPMFAVCFFGYNLGRKL-------QVKDENTPLTKPQ 287
+T+ EG + +KG A L P A+ F Y + + Q ++ P+
Sbjct: 182 KTIVKEGGIASLFKGSLATLARDGPGSALYFASYEISKNYLNSRQPRQDAGKDEPVNILN 241
Query: 288 IFAAGMLSGVFTTAIMTPGERIKCLLQVQGASKEPPKYKGPGDVIRKLY-KEGGIRSIYK 464
+ AG ++G+ + P + IK LQ + +++Y + GGI+ +
Sbjct: 242 VCLAGGIAGMSMWLAVFPIDTIKTKLQASSTRQNMLS------ATKEIYLQRGGIKGFFP 295
Query: 465 GTAATLLRDIPATGTYFMSYEWLKEILTPEG 557
G LLR PA F+ E + G
Sbjct: 296 GLGPALLRSFPANAATFLGVEMTHSLFKKYG 326
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 110,578,605
Number of Sequences: 369166
Number of extensions: 2532600
Number of successful extensions: 7311
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 6111
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6627
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 8982382310
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)