Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_009_I19
(782 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P49900|ARGI_RANCA Arginase, hepatic 232 8e-61
sp|P78540|ARGI2_HUMAN Arginase-2, mitochondrial precursor (... 223 5e-58
sp|P07824|ARGI1_RAT Arginase-1 (Type I arginase) (Liver-typ... 219 7e-57
sp|Q61176|ARGI1_MOUSE Arginase-1 (Type I arginase) (Liver-t... 218 1e-56
sp|Q95JC8|ARGI1_PIG Arginase-1 (Type I arginase) (Liver-typ... 218 1e-56
sp|O08691|ARGI2_MOUSE Arginase-2, mitochondrial precursor (... 218 1e-56
sp|P05089|ARGI1_HUMAN Arginase-1 (Type I arginase) (Liver-t... 218 2e-56
sp|Q91555|ARGN3_XENLA Arginase, non-hepatic 3 216 6e-56
sp|O08701|ARGI2_RAT Arginase-2, mitochondrial precursor (Ar... 215 1e-55
sp|Q91554|ARGN2_XENLA Arginase, non-hepatic 2 215 1e-55
>sp|P49900|ARGI_RANCA Arginase, hepatic
Length = 323
Score = 232 bits (592), Expect = 8e-61
Identities = 115/209 (55%), Positives = 149/209 (71%), Gaps = 1/209 (0%)
Frame = +1
Query: 1 SITTGTILGHARRHEDLCVIWVDAHADINTPLSSSSGNMHGMPLSFLIHEMQNEMPWIEE 180
S+ GTI GHA+ H DLCV+WVDAHADINTP++S SGN+HG P+SFLI E+Q ++P I
Sbjct: 103 SLAVGTITGHAKVHPDLCVVWVDAHADINTPITSPSGNLHGQPVSFLIRELQTKVPAIPG 162
Query: 181 FKDIPPVISAKNIVYIGLRSVDPYERHVLNKYNIKSFSMEDIDRDGINCVIQQAIKAVNP 360
F + P +SAK+IVYIGLR VDP E ++L IKS+SM D+DR IN V+++ I+ +
Sbjct: 163 FSWVQPSLSAKDIVYIGLRDVDPGEHYILKTLGIKSYSMSDVDRLTINKVMEETIEFLVG 222
Query: 361 NLDRYFHLSFDIDALDPLYAPSTGTAVPGGLTLREGVYLCEQLFNTGKLAAIDVTEINTQ 540
R HLSFDID LDP AP+TGT VPGGLT REG+Y+ EQL+NTG L+A+D+ E+N
Sbjct: 223 KKKRPIHLSFDIDGLDPSVAPATGTPVPGGLTYREGMYITEQLYNTGLLSAVDMMEVNPS 282
Query: 541 VG-TYSEVVTTINSATKIIQGCLGIKREG 624
G T E T+N++ +I C G REG
Sbjct: 283 RGETERESKLTVNTSLNMILSCFGKAREG 311
>sp|P78540|ARGI2_HUMAN Arginase-2, mitochondrial precursor (Arginase II) (Non-hepatic
arginase) (Kidney-type arginase)
Length = 354
Score = 223 bits (568), Expect = 5e-58
Identities = 112/213 (52%), Positives = 146/213 (68%), Gaps = 1/213 (0%)
Frame = +1
Query: 1 SITTGTILGHARRHEDLCVIWVDAHADINTPLSSSSGNMHGMPLSFLIHEMQNEMPWIEE 180
S+ GTI GHAR DLCV+WVDAHADINTPL++SSGN+HG P+SFL+ E+Q+++P +
Sbjct: 121 SLAIGTISGHARHCPDLCVVWVDAHADINTPLTTSSGNLHGQPVSFLLRELQDKVPQLPG 180
Query: 181 FKDIPPVISAKNIVYIGLRSVDPYERHVLNKYNIKSFSMEDIDRDGINCVIQQAIKAVNP 360
F I P IS+ +IVYIGLR VDP E +L Y+I+ FSM DIDR GI V+++ +
Sbjct: 181 FSWIKPCISSASIVYIGLRDVDPPEHFILKNYDIQYFSMRDIDRLGIQKVMERTFDLLIG 240
Query: 361 NLDRYFHLSFDIDALDPLYAPSTGTAVPGGLTLREGVYLCEQLFNTGKLAAIDVTEINTQ 540
R HLSFDIDA DP AP+TGT V GGLT REG+Y+ E++ NTG L+A+D+ E+N Q
Sbjct: 241 KRQRPIHLSFDIDAFDPTLAPATGTPVVGGLTYREGMYIAEEIHNTGLLSALDLVEVNPQ 300
Query: 541 VGT-YSEVVTTINSATKIIQGCLGIKREGAPLI 636
+ T E TT N A +I G REG ++
Sbjct: 301 LATSEEEAKTTANLAVDVIASSFGQTREGGHIV 333
>sp|P07824|ARGI1_RAT Arginase-1 (Type I arginase) (Liver-type arginase)
Length = 323
Score = 219 bits (558), Expect = 7e-57
Identities = 105/217 (48%), Positives = 147/217 (67%), Gaps = 1/217 (0%)
Frame = +1
Query: 1 SITTGTILGHARRHEDLCVIWVDAHADINTPLSSSSGNMHGMPLSFLIHEMQNEMPWIEE 180
S+ G+I GHAR H DLCVIWVDAH DINTPL++SSGN+HG P++FL+ E++ + P +
Sbjct: 102 SMAIGSISGHARVHPDLCVIWVDAHTDINTPLTTSSGNLHGQPVAFLLKELKGKFPDVPG 161
Query: 181 FKDIPPVISAKNIVYIGLRSVDPYERHVLNKYNIKSFSMEDIDRDGINCVIQQAIKAVNP 360
F + P ISAK+IVYIGLR VDP E +++ IK FSM ++D+ GI V+++ +
Sbjct: 162 FSWVTPCISAKDIVYIGLRDVDPGEHYIIKTLGIKYFSMTEVDKLGIGKVMEETFSYLLG 221
Query: 361 NLDRYFHLSFDIDALDPLYAPSTGTAVPGGLTLREGVYLCEQLFNTGKLAAIDVTEINTQ 540
R HLSFD+D LDP++ P+TGT V GGL+ REG+Y+ E+++ TG L+ +D+ E+N
Sbjct: 222 RKKRPIHLSFDVDGLDPVFTPATGTPVVGGLSYREGLYITEEIYKTGLLSGLDIMEVNPT 281
Query: 541 VG-TYSEVVTTINSATKIIQGCLGIKREGAPLITPDY 648
+G T EV T+N+A + C G KREG DY
Sbjct: 282 LGKTPEEVTRTVNTAVALTLSCFGTKREGNHKPETDY 318
>sp|Q61176|ARGI1_MOUSE Arginase-1 (Type I arginase) (Liver-type arginase)
Length = 323
Score = 218 bits (556), Expect = 1e-56
Identities = 105/217 (48%), Positives = 147/217 (67%), Gaps = 1/217 (0%)
Frame = +1
Query: 1 SITTGTILGHARRHEDLCVIWVDAHADINTPLSSSSGNMHGMPLSFLIHEMQNEMPWIEE 180
S+ G+I GHAR H DLCVIWVDAH DINTPL++SSGN+HG P+SFL+ E++ + P +
Sbjct: 102 SLAVGSISGHARVHPDLCVIWVDAHTDINTPLTTSSGNLHGQPVSFLLKELKGKFPDVPG 161
Query: 181 FKDIPPVISAKNIVYIGLRSVDPYERHVLNKYNIKSFSMEDIDRDGINCVIQQAIKAVNP 360
F + P ISAK+IVYIGLR VDP E +++ IK FSM ++D+ GI V+++ +
Sbjct: 162 FSWVTPCISAKDIVYIGLRDVDPGEHYIIKTLGIKYFSMTEVDKLGIGKVMEETFSYLLG 221
Query: 361 NLDRYFHLSFDIDALDPLYAPSTGTAVPGGLTLREGVYLCEQLFNTGKLAAIDVTEINTQ 540
R HLSFD+D LDP + P+TGT V GGL+ REG+Y+ E+++ TG L+ +D+ E+N
Sbjct: 222 RKKRPIHLSFDVDGLDPAFTPATGTPVLGGLSYREGLYITEEIYKTGLLSGLDIMEVNPT 281
Query: 541 VG-TYSEVVTTINSATKIIQGCLGIKREGAPLITPDY 648
+G T EV +T+N+A + C G +REG DY
Sbjct: 282 LGKTAEEVKSTVNTAVALTLACFGTQREGNHKPGTDY 318
>sp|Q95JC8|ARGI1_PIG Arginase-1 (Type I arginase) (Liver-type arginase)
Length = 322
Score = 218 bits (556), Expect = 1e-56
Identities = 101/209 (48%), Positives = 146/209 (69%), Gaps = 1/209 (0%)
Frame = +1
Query: 1 SITTGTILGHARRHEDLCVIWVDAHADINTPLSSSSGNMHGMPLSFLIHEMQNEMPWIEE 180
S+ G+I GHAR H DLCVIWVDAH DINTPL++++GN+HG P+SFL+ E++ ++P +
Sbjct: 102 SMAIGSISGHARVHPDLCVIWVDAHTDINTPLTTTTGNLHGQPVSFLLKELKEKIPEVPG 161
Query: 181 FKDIPPVISAKNIVYIGLRSVDPYERHVLNKYNIKSFSMEDIDRDGINCVIQQAIKAVNP 360
+ P +SAK+IVYIGLR VDP E ++L IK FSM ++D+ GI V+++A +
Sbjct: 162 LSWVTPCLSAKDIVYIGLRDVDPAEHYILKTLGIKYFSMIEVDKLGIGKVMEEAFSYLLG 221
Query: 361 NLDRYFHLSFDIDALDPLYAPSTGTAVPGGLTLREGVYLCEQLFNTGKLAAIDVTEINTQ 540
R HLSFD+D LDP + P+TGT V GGL+ REG+Y+ E+++ TG L+ +D+ E+N
Sbjct: 222 RKKRPIHLSFDVDGLDPFFTPATGTPVHGGLSYREGIYITEEIYKTGLLSGLDIMEVNPS 281
Query: 541 VG-TYSEVVTTINSATKIIQGCLGIKREG 624
+G T EV T+N+A ++ C G+ REG
Sbjct: 282 LGKTPEEVTRTVNTAVALVLACFGVAREG 310
>sp|O08691|ARGI2_MOUSE Arginase-2, mitochondrial precursor (Arginase II) (Non-hepatic
arginase) (Kidney-type arginase)
Length = 354
Score = 218 bits (555), Expect = 1e-56
Identities = 111/213 (52%), Positives = 142/213 (66%), Gaps = 1/213 (0%)
Frame = +1
Query: 1 SITTGTILGHARRHEDLCVIWVDAHADINTPLSSSSGNMHGMPLSFLIHEMQNEMPWIEE 180
S+ GTI+GHAR DLCVIWVDAHADINTPL++ SGN+HG PLSFLI E+Q+++P +
Sbjct: 121 SLAIGTIIGHARHRPDLCVIWVDAHADINTPLTTVSGNIHGQPLSFLIKELQDKVPQLPG 180
Query: 181 FKDIPPVISAKNIVYIGLRSVDPYERHVLNKYNIKSFSMEDIDRDGINCVIQQAIKAVNP 360
F I P +S NIVYIGLR V+P E +L Y+I+ FSM +IDR GI V++Q +
Sbjct: 181 FSWIKPCLSPPNIVYIGLRDVEPPEHFILKNYDIQYFSMREIDRLGIQKVMEQTFDRLIG 240
Query: 361 NLDRYFHLSFDIDALDPLYAPSTGTAVPGGLTLREGVYLCEQLFNTGKLAAIDVTEINTQ 540
R HLSFDIDA DP AP+TGT V GGLT REGVY+ E++ NTG L+A+D+ E+N
Sbjct: 241 KRQRPIHLSFDIDAFDPKLAPATGTPVVGGLTYREGVYITEEIHNTGLLSALDLVEVNPH 300
Query: 541 VGT-YSEVVTTINSATKIIQGCLGIKREGAPLI 636
+ T E T A +I G REG ++
Sbjct: 301 LATSEEEAKATARLAVDVIASSFGQTREGGHIV 333
>sp|P05089|ARGI1_HUMAN Arginase-1 (Type I arginase) (Liver-type arginase)
Length = 322
Score = 218 bits (554), Expect = 2e-56
Identities = 105/209 (50%), Positives = 145/209 (69%), Gaps = 1/209 (0%)
Frame = +1
Query: 1 SITTGTILGHARRHEDLCVIWVDAHADINTPLSSSSGNMHGMPLSFLIHEMQNEMPWIEE 180
S+ G+I GHAR H DL VIWVDAH DINTPL+++SGN+HG P+SFL+ E++ ++P +
Sbjct: 102 SLAIGSISGHARVHPDLGVIWVDAHTDINTPLTTTSGNLHGQPVSFLLKELKGKIPDVPG 161
Query: 181 FKDIPPVISAKNIVYIGLRSVDPYERHVLNKYNIKSFSMEDIDRDGINCVIQQAIKAVNP 360
F + P ISAK+IVYIGLR VDP E ++L IK FSM ++DR GI V+++ + +
Sbjct: 162 FSWVTPCISAKDIVYIGLRDVDPGEHYILKTLGIKYFSMTEVDRLGIGKVMEETLSYLLG 221
Query: 361 NLDRYFHLSFDIDALDPLYAPSTGTAVPGGLTLREGVYLCEQLFNTGKLAAIDVTEINTQ 540
R HLSFD+D LDP + P+TGT V GGLT REG+Y+ E+++ TG L+ +D+ E+N
Sbjct: 222 RKKRPIHLSFDVDGLDPSFTPATGTPVVGGLTYREGLYITEEIYKTGLLSGLDIMEVNPS 281
Query: 541 VG-TYSEVVTTINSATKIIQGCLGIKREG 624
+G T EV T+N+A I C G+ REG
Sbjct: 282 LGKTPEEVTRTVNTAVAITLACFGLAREG 310
>sp|Q91555|ARGN3_XENLA Arginase, non-hepatic 3
Length = 360
Score = 216 bits (550), Expect = 6e-56
Identities = 110/210 (52%), Positives = 143/210 (68%), Gaps = 1/210 (0%)
Frame = +1
Query: 1 SITTGTILGHARRHEDLCVIWVDAHADINTPLSSSSGNMHGMPLSFLIHEMQNEMPWIEE 180
S+ G+I GHA++ DLCVIWVDAHADINTPL++ SGN+HG P+SFL+ E+Q+++P I
Sbjct: 123 SLAFGSITGHAQQCPDLCVIWVDAHADINTPLTTPSGNLHGQPVSFLLRELQDKIPPIPG 182
Query: 181 FKDIPPVISAKNIVYIGLRSVDPYERHVLNKYNIKSFSMEDIDRDGINCVIQQAIKAVNP 360
F P +S +IVYIGLR +DP E+ +L YNI +SM ID GI V+++ +
Sbjct: 183 FSWAKPCLSKSDIVYIGLRDLDPAEQFILKNYNISYYSMRHIDCMGIRKVMEKTFDQLLG 242
Query: 361 NLDRYFHLSFDIDALDPLYAPSTGTAVPGGLTLREGVYLCEQLFNTGKLAAIDVTEINTQ 540
DR HLSFDIDA DP AP+TGT V GGLT REGVY+ E++ NTG L+A+D+ E+N
Sbjct: 243 RRDRPIHLSFDIDAFDPALAPATGTPVIGGLTYREGVYITEEIHNTGMLSALDLVEVNPV 302
Query: 541 VGTYS-EVVTTINSATKIIQGCLGIKREGA 627
+ T S EV T N A +I C G REGA
Sbjct: 303 LATTSEEVKATANLAVDVIASCFGQTREGA 332
>sp|O08701|ARGI2_RAT Arginase-2, mitochondrial precursor (Arginase II) (Non-hepatic
arginase) (Kidney-type arginase)
Length = 354
Score = 215 bits (548), Expect = 1e-55
Identities = 109/209 (52%), Positives = 141/209 (67%), Gaps = 1/209 (0%)
Frame = +1
Query: 1 SITTGTILGHARRHEDLCVIWVDAHADINTPLSSSSGNMHGMPLSFLIHEMQNEMPWIEE 180
S+ GTI GHAR H DLCVIWVDAHADINTPL++ SGN+HG PLSFLI E+Q+++P +
Sbjct: 121 SLAIGTISGHARHHPDLCVIWVDAHADINTPLTTVSGNIHGQPLSFLIRELQDKVPQLPG 180
Query: 181 FKDIPPVISAKNIVYIGLRSVDPYERHVLNKYNIKSFSMEDIDRDGINCVIQQAIKAVNP 360
F I P +S N+VYIGLR V+P E +L ++I+ FSM DIDR GI V++Q +
Sbjct: 181 FSWIKPCLSPPNLVYIGLRDVEPAEHFILKSFDIQYFSMRDIDRLGIQKVMEQTFDRLIG 240
Query: 361 NLDRYFHLSFDIDALDPLYAPSTGTAVPGGLTLREGVYLCEQLFNTGKLAAIDVTEINTQ 540
R HLSFDIDA DP AP+TGT V GGLT REG+Y+ E++ +TG L+A+D+ E+N
Sbjct: 241 KRKRPIHLSFDIDAFDPKLAPATGTPVVGGLTYREGLYITEEIHSTGLLSALDLVEVNPH 300
Query: 541 VGT-YSEVVTTINSATKIIQGCLGIKREG 624
+ T E T + A +I G REG
Sbjct: 301 LATSEEEAKATASLAVDVIASSFGQTREG 329
>sp|Q91554|ARGN2_XENLA Arginase, non-hepatic 2
Length = 360
Score = 215 bits (547), Expect = 1e-55
Identities = 109/210 (51%), Positives = 141/210 (67%), Gaps = 1/210 (0%)
Frame = +1
Query: 1 SITTGTILGHARRHEDLCVIWVDAHADINTPLSSSSGNMHGMPLSFLIHEMQNEMPWIEE 180
S+ G+I GHA++ DLCVIWVDAHADINTPL++ SGN+HG P+SFL+ E+Q+++P I
Sbjct: 123 SLAFGSITGHAQQCPDLCVIWVDAHADINTPLTTPSGNLHGQPVSFLLRELQDKVPPIPG 182
Query: 181 FKDIPPVISAKNIVYIGLRSVDPYERHVLNKYNIKSFSMEDIDRDGINCVIQQAIKAVNP 360
F P +S +IVYIGLR +DP E+ +L YNI +SM ID GI V+++ +
Sbjct: 183 FSWAKPCLSKSDIVYIGLRDLDPAEQFILKNYNISYYSMRHIDCMGIKKVMEKTFDQLLG 242
Query: 361 NLDRYFHLSFDIDALDPLYAPSTGTAVPGGLTLREGVYLCEQLFNTGKLAAIDVTEIN-T 537
DR HLSFDIDA DP AP+TGT V GGLT REGVY+ E++ NTG L+A+D+ E+N
Sbjct: 243 RRDRPIHLSFDIDAFDPALAPATGTPVIGGLTYREGVYITEEIHNTGMLSAVDLVEVNPV 302
Query: 538 QVGTYSEVVTTINSATKIIQGCLGIKREGA 627
T EV T N A +I C G REGA
Sbjct: 303 LAATSEEVKATANLAVDVIASCFGQTREGA 332
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 85,682,505
Number of Sequences: 369166
Number of extensions: 1758073
Number of successful extensions: 4713
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4478
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4665
length of database: 68,354,980
effective HSP length: 108
effective length of database: 48,403,600
effective search space used: 7357347200
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)