Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_009_H16
(861 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q61879|MYH10_MOUSE Myosin-10 (Myosin heavy chain, nonmus... 173 6e-43
sp|Q9JLT0|MYH10_RAT Myosin-10 (Myosin heavy chain, nonmuscl... 173 6e-43
sp|Q27991|MYH10_BOVIN Myosin-10 (Myosin heavy chain, nonmus... 173 6e-43
sp|P35580|MYH10_HUMAN Myosin-10 (Myosin heavy chain, nonmus... 171 3e-42
sp|P35579|MYH9_HUMAN Myosin-9 (Myosin heavy chain, nonmuscl... 170 4e-42
sp|Q99105|MYSU_RABIT Myosin heavy chain, embryonic smooth m... 170 4e-42
sp|Q8VDD5|MYH9_MOUSE Myosin-9 (Myosin heavy chain, nonmuscl... 170 5e-42
sp|P14105|MYH9_CHICK Myosin-9 (Myosin heavy chain, nonmuscl... 169 7e-42
sp|P10587|MYH11_CHICK Myosin-11 (Myosin heavy chain, gizzar... 166 1e-40
sp|P35749|MYH11_HUMAN Myosin-11 (Myosin heavy chain, smooth... 165 2e-40
>sp|Q61879|MYH10_MOUSE Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy
chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin
heavy chain, type B) (Nonmuscle myosin heavy chain-B)
(NMMHC-B)
Length = 1976
Score = 173 bits (438), Expect = 6e-43
Identities = 95/279 (34%), Positives = 161/279 (57%)
Frame = +3
Query: 18 LNRQLNELVSNKDDVGKNIGSLKNAKIQLENDLENCKKTIEELEEENATLQMNKERIEMQ 197
L + +L+S+KDDVGKN+ L+ +K LE +E + +EELE+E + K R+E+
Sbjct: 1509 LRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVN 1568
Query: 198 LTATKAQLDRELSSKDEMHDEQFKILNKKLRDTEATLEEEQKQRTSLASLKKKLEIENVD 377
+ A KAQ +R+L ++DE ++E+ ++L K++R+ EA LE+E+KQR + KKK+EI+ D
Sbjct: 1569 MQAMKAQFERDLQTRDEQNEEKKRLLLKQVRELEAELEDERKQRALAVASKKKMEIDLKD 1628
Query: 378 LMNQXXXXXXXXXXXXRQIKKHQGTSLNSQREMQEVLNAKNEALKQIKELEKRLRAAESS 557
L Q +Q++K Q + QRE++E +++E Q KE EK+L++ E+
Sbjct: 1629 LEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAE 1688
Query: 558 TNQLIEDLSQSERIKRTLISERDDALEEIATLTVNKDTAIADKKRIESNLSALNMDYXXX 737
QL E+L+ SER +R ERD+ +EIA K + +K+R+E+ ++ L +
Sbjct: 1689 ILQLQEELASSERARRHAEQERDELADEIANSASGKSALLDEKRRLEARIAQLEEELEEE 1748
Query: 738 XXXXXXXXDKNKKVTNQLEQVQNELNVERQNATRLENQK 854
D+ +K T Q++ + EL ER A + +N +
Sbjct: 1749 QSNMELLNDRFRKTTLQVDTLNTELAAERSAAQKSDNAR 1787
Score = 58.2 bits (139), Expect = 3e-08
Identities = 55/298 (18%), Positives = 128/298 (42%), Gaps = 30/298 (10%)
Frame = +3
Query: 9 KSLLNRQLN---ELVSNKDDVGKNIGSLKNAKIQLENDLENCKKTIEELEEENATLQMNK 179
K++L QL EL + +++ + + K +LE L + + +EE EE N LQ K
Sbjct: 889 KNILAEQLQAETELFAEAEEMRARLAAKKQ---ELEEILHDLESRVEEEEERNQILQNEK 945
Query: 180 ERIEMQLTATKAQLDRELSSKDEMHDEQF---------------------------KILN 278
++++ + + QLD E ++ ++ E+ K++
Sbjct: 946 KKMQAHIQDLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEVLLLEDQNSKFIKEKKLME 1005
Query: 279 KKLRDTEATLEEEQKQRTSLASLKKKLEIENVDLMNQXXXXXXXXXXXXRQIKKHQGTSL 458
++ + + L EE+++ +LA ++ K E+ DL ++KK + T
Sbjct: 1006 DRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDL--------------EERLKKEEKT-- 1049
Query: 459 NSQREMQEVLNAKNEALKQIKELEKRLRAAESSTNQLIEDLSQSERIKRTLISERDDALE 638
QE+ AK + + +L+ ++ ++ ++L L++ E + ++ DD
Sbjct: 1050 -----RQELEKAKRKLDGETTDLQDQIAELQAQVDELKVQLTKKEEELQGALARGDDE-- 1102
Query: 639 EIATLTVNKDTAIADKKRIESNLSALNMDYXXXXXXXXXXXDKNKKVTNQLEQVQNEL 812
T++K+ A+ + +++ ++ L D+ + + ++ +LE ++ EL
Sbjct: 1103 -----TLHKNNALKVARELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTEL 1155
Score = 50.8 bits (120), Expect = 5e-06
Identities = 53/241 (21%), Positives = 117/241 (48%), Gaps = 8/241 (3%)
Frame = +3
Query: 9 KSLLNRQLNELVSNKDDVGKNIGSLKNAKIQLENDLENCKKTIEELEEENATLQMNKERI 188
K+ L + L ++ ++ + L+ K + E+ + ++EL + + + ++ R+
Sbjct: 1219 KANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVS--EGDRLRV 1276
Query: 189 EMQLTATKAQ--LDRELSSKDEMHDEQFKI------LNKKLRDTEATLEEEQKQRTSLAS 344
E+ A K Q LD + +E + K L +L+DT+ L+EE +Q+ +L+S
Sbjct: 1277 ELAEKANKLQNELDNVSTLLEEAEKKGIKFAKDAAGLESQLQDTQELLQEETRQKLNLSS 1336
Query: 345 LKKKLEIENVDLMNQXXXXXXXXXXXXRQIKKHQGTSLNSQREMQEVLNAKNEALKQIKE 524
++LE E L Q +Q+ Q ++++++ + L E+L++ K
Sbjct: 1337 RIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGT-IESLEEAK- 1394
Query: 525 LEKRLRAAESSTNQLIEDLSQSERIKRTLISERDDALEEIATLTVNKDTAIADKKRIESN 704
+K L+ E+ + +L E + +++++T ++ +E+ LTV+ D +++I SN
Sbjct: 1395 -KKLLKDVEALSQRLEEKVLAYDKLEKT----KNRLQQELDDLTVDLD----HQRQIVSN 1445
Query: 705 L 707
L
Sbjct: 1446 L 1446
Score = 48.1 bits (113), Expect = 3e-05
Identities = 62/316 (19%), Positives = 121/316 (38%), Gaps = 35/316 (11%)
Frame = +3
Query: 3 NSKSLLNRQLNELVSNKDDVGKNIGSLKNAKIQLENDLENCKKTIEELEEENATLQMNKE 182
+ + L+ Q+ EL + + + L +L+N+L+N +EE E++ +
Sbjct: 1252 HKRKKLDAQVQELHAKVSEGDRLRVELAEKANKLQNELDNVSTLLEEAEKKGIKFAKDAA 1311
Query: 183 RIEMQLTATK-----------------AQLDRELSSKDEMHDE----------QFKILNK 281
+E QL T+ QL+ E +S E +E Q L
Sbjct: 1312 GLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQS 1371
Query: 282 KLRDTEATLEEEQKQRTSLASLKKKLEIENVDLMNQXXXXXXXXXXXXRQIKKH------ 443
+L DT+ ++++ SL KKKL +++V+ ++Q + K
Sbjct: 1372 QLADTKKKVDDDLGTIESLEEAKKKL-LKDVEALSQRLEEKVLAYDKLEKTKNRLQQELD 1430
Query: 444 -QGTSLNSQREMQEVLNAKNEALKQIKELEKRLRAAESSTNQLIEDLSQSERIKR-TLIS 617
L+ QR++ L K + Q+ EK + A + E ++ + K +L
Sbjct: 1431 DLTVDLDHQRQIVSNLEKKQKKFDQLLAEEKGISARYAEERDRAEAEAREKETKALSLAR 1490
Query: 618 ERDDALEEIATLTVNKDTAIADKKRIESNLSALNMDYXXXXXXXXXXXDKNKKVTNQLEQ 797
++ALE AD + + S+ + + + +++ QLE+
Sbjct: 1491 ALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEE 1550
Query: 798 VQNELNVERQNATRLE 845
+++EL RLE
Sbjct: 1551 LEDELQATEDAKLRLE 1566
Score = 38.1 bits (87), Expect = 0.032
Identities = 42/221 (19%), Positives = 83/221 (37%), Gaps = 36/221 (16%)
Frame = +3
Query: 51 KDDVGKNIGSLKNAKIQLENDLENCKKTIEELEEENATLQMNKERIEMQLTATKAQLD-- 224
+D++ I + + K L ++ + I +LEEE Q N E + + T Q+D
Sbjct: 1710 RDELADEIANSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTL 1769
Query: 225 -------RELSSKDEMHDEQFKILNKKLR--------------------------DTEAT 305
R + K + +Q + NK+L+ E
Sbjct: 1770 NTELAAERSAAQKSDNARQQLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQ 1829
Query: 306 LEEEQKQRTSLASLKKKLEIENVDLMNQXXXXXXXXXXXXRQIKKHQGTSLNSQREMQEV 485
LE+E K+R + L ++ E + ++ Q Q++K +R+++E
Sbjct: 1830 LEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQLEEA 1889
Query: 486 LNAKNEALKQIKELEKRLRAAESSTNQLIEDLSQ-SERIKR 605
A ++L++ L A + L ++S R++R
Sbjct: 1890 EEEATRANASRRKLQRELDDATEANEGLSREVSTLKNRLRR 1930
>sp|Q9JLT0|MYH10_RAT Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy
chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin
heavy chain, type B) (Nonmuscle myosin heavy chain-B)
(NMMHC-B)
Length = 1976
Score = 173 bits (438), Expect = 6e-43
Identities = 95/279 (34%), Positives = 161/279 (57%)
Frame = +3
Query: 18 LNRQLNELVSNKDDVGKNIGSLKNAKIQLENDLENCKKTIEELEEENATLQMNKERIEMQ 197
L + +L+S+KDDVGKN+ L+ +K LE +E + +EELE+E + K R+E+
Sbjct: 1509 LRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVN 1568
Query: 198 LTATKAQLDRELSSKDEMHDEQFKILNKKLRDTEATLEEEQKQRTSLASLKKKLEIENVD 377
+ A KAQ +R+L ++DE ++E+ ++L K++R+ EA LE+E+KQR + KKK+EI+ D
Sbjct: 1569 MQAMKAQFERDLQTRDEQNEEKKRLLLKQVRELEAELEDERKQRALAVASKKKMEIDLKD 1628
Query: 378 LMNQXXXXXXXXXXXXRQIKKHQGTSLNSQREMQEVLNAKNEALKQIKELEKRLRAAESS 557
L Q +Q++K Q + QRE++E +++E Q KE EK+L++ E+
Sbjct: 1629 LEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAE 1688
Query: 558 TNQLIEDLSQSERIKRTLISERDDALEEIATLTVNKDTAIADKKRIESNLSALNMDYXXX 737
QL E+L+ SER +R ERD+ +EIA K + +K+R+E+ ++ L +
Sbjct: 1689 ILQLQEELASSERARRHAEQERDELADEIANSASGKSALLDEKRRLEARIAQLEEELEEE 1748
Query: 738 XXXXXXXXDKNKKVTNQLEQVQNELNVERQNATRLENQK 854
D+ +K T Q++ + EL ER A + +N +
Sbjct: 1749 QSNMELLNDRFRKTTLQVDTLNTELAAERSAAQKSDNAR 1787
Score = 58.9 bits (141), Expect = 2e-08
Identities = 60/298 (20%), Positives = 119/298 (39%), Gaps = 14/298 (4%)
Frame = +3
Query: 3 NSKSLLNRQLNELVSNKDDVGKNIGSLKNAKIQLENDLENCKKTIEELEEENATLQMNKE 182
N K + + +L D+ L+ K+ E ++ ++ + LE++N+ K+
Sbjct: 943 NEKKKMQAHIQDLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEVLLLEDQNSKFIKEKK 1002
Query: 183 RIEMQLTATKAQLDRELSSKDEMHDEQFKILNKK---LRDTEATLEEEQKQRTSLASLKK 353
+E ++ A+ +L+ ++E KI NK+ + D E L++E+K R L K+
Sbjct: 1003 LMEDRI----AECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKR 1058
Query: 354 KLEIENVDLMNQXXXXXXXXXXXXRQIKKHQGTSLNSQREMQEVLNAKNEALKQIKELEK 533
KL+ E DL +Q Q+ K + + + KN ALK +EL+
Sbjct: 1059 KLDGETTDLQDQIAELQAQVDELKVQLTKKEEELQGALARGDDETLHKNNALKVARELQA 1118
Query: 534 RL----------RAAESSTNQLIEDLSQSERIKRTLISERDDALEEIATLTVNKDTAIAD 683
++ +A+ + + DLS+ +T + + D L ++ +A+
Sbjct: 1119 QIAELQEDFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAE 1178
Query: 684 -KKRIESNLSALNMDYXXXXXXXXXXXDKNKKVTNQLEQVQNELNVERQNATRLENQK 854
KK +E D ++ LE++ +L ++ LE K
Sbjct: 1179 LKKALEDETK----------NHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNK 1226
Score = 50.8 bits (120), Expect = 5e-06
Identities = 40/243 (16%), Positives = 113/243 (46%), Gaps = 6/243 (2%)
Frame = +3
Query: 102 LENDLENCKKTIEELEEENATLQMNKERIEMQLTATKAQLDRE------LSSKDEMHDEQ 263
L+N+ + + I++LEE+ + +++++++ +A++ + L ++ ++
Sbjct: 941 LQNEKKKMQAHIQDLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEVLLLEDQNSKFIKE 1000
Query: 264 FKILNKKLRDTEATLEEEQKQRTSLASLKKKLEIENVDLMNQXXXXXXXXXXXXRQIKKH 443
K++ ++ + + L EE+++ +LA ++ K E+ DL ++KK
Sbjct: 1001 KKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDL--------------EERLKKE 1046
Query: 444 QGTSLNSQREMQEVLNAKNEALKQIKELEKRLRAAESSTNQLIEDLSQSERIKRTLISER 623
+ T QE+ AK + + +L+ ++ ++ ++L L++ E + ++
Sbjct: 1047 EKT-------RQELEKAKRKLDGETTDLQDQIAELQAQVDELKVQLTKKEEELQGALARG 1099
Query: 624 DDALEEIATLTVNKDTAIADKKRIESNLSALNMDYXXXXXXXXXXXDKNKKVTNQLEQVQ 803
DD T++K+ A+ + +++ ++ L D+ + + ++ +LE ++
Sbjct: 1100 DDE-------TLHKNNALKVARELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALK 1152
Query: 804 NEL 812
EL
Sbjct: 1153 TEL 1155
Score = 50.4 bits (119), Expect = 6e-06
Identities = 53/241 (21%), Positives = 116/241 (48%), Gaps = 8/241 (3%)
Frame = +3
Query: 9 KSLLNRQLNELVSNKDDVGKNIGSLKNAKIQLENDLENCKKTIEELEEENATLQMNKERI 188
K+ L + L ++ ++ + L+ K + E+ + ++EL + + + ++ R+
Sbjct: 1219 KANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVS--EGDRLRV 1276
Query: 189 EMQLTATKAQ--LDRELSSKDEMHDEQFKI------LNKKLRDTEATLEEEQKQRTSLAS 344
E+ A K Q LD + +E + K L +L+DT+ L+EE +Q+ +L+S
Sbjct: 1277 ELAEKANKLQNELDNVSTLLEEAEKKGMKFAKDAAGLESQLQDTQELLQEETRQKLNLSS 1336
Query: 345 LKKKLEIENVDLMNQXXXXXXXXXXXXRQIKKHQGTSLNSQREMQEVLNAKNEALKQIKE 524
++LE E L Q +Q+ Q ++++++ + L E L++ K
Sbjct: 1337 RIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGT-IEGLEEAK- 1394
Query: 525 LEKRLRAAESSTNQLIEDLSQSERIKRTLISERDDALEEIATLTVNKDTAIADKKRIESN 704
+K L+ E+ + +L E + +++++T ++ +E+ LTV+ D +++I SN
Sbjct: 1395 -KKLLKDVEALSQRLEEKVLAYDKLEKT----KNRLQQELDDLTVDLD----HQRQIVSN 1445
Query: 705 L 707
L
Sbjct: 1446 L 1446
Score = 46.6 bits (109), Expect = 9e-05
Identities = 61/316 (19%), Positives = 120/316 (37%), Gaps = 35/316 (11%)
Frame = +3
Query: 3 NSKSLLNRQLNELVSNKDDVGKNIGSLKNAKIQLENDLENCKKTIEELEEENATLQMNKE 182
+ + L+ Q+ EL + + + L +L+N+L+N +EE E++ +
Sbjct: 1252 HKRKKLDAQVQELHAKVSEGDRLRVELAEKANKLQNELDNVSTLLEEAEKKGMKFAKDAA 1311
Query: 183 RIEMQLTATK-----------------AQLDRELSSKDEMHDE----------QFKILNK 281
+E QL T+ QL+ E +S E +E Q L
Sbjct: 1312 GLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQS 1371
Query: 282 KLRDTEATLEEEQKQRTSLASLKKKLEIENVDLMNQXXXXXXXXXXXXRQIKKH------ 443
+L DT+ ++++ L KKKL +++V+ ++Q + K
Sbjct: 1372 QLADTKKKVDDDLGTIEGLEEAKKKL-LKDVEALSQRLEEKVLAYDKLEKTKNRLQQELD 1430
Query: 444 -QGTSLNSQREMQEVLNAKNEALKQIKELEKRLRAAESSTNQLIEDLSQSERIKR-TLIS 617
L+ QR++ L K + Q+ EK + A + E ++ + K +L
Sbjct: 1431 DLTVDLDHQRQIVSNLEKKQKKFDQLLAEEKGISARYAEERDRAEAEAREKETKALSLAR 1490
Query: 618 ERDDALEEIATLTVNKDTAIADKKRIESNLSALNMDYXXXXXXXXXXXDKNKKVTNQLEQ 797
++ALE AD + + S+ + + + +++ QLE+
Sbjct: 1491 ALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEE 1550
Query: 798 VQNELNVERQNATRLE 845
+++EL RLE
Sbjct: 1551 LEDELQATEDAKLRLE 1566
Score = 38.1 bits (87), Expect = 0.032
Identities = 42/221 (19%), Positives = 83/221 (37%), Gaps = 36/221 (16%)
Frame = +3
Query: 51 KDDVGKNIGSLKNAKIQLENDLENCKKTIEELEEENATLQMNKERIEMQLTATKAQLD-- 224
+D++ I + + K L ++ + I +LEEE Q N E + + T Q+D
Sbjct: 1710 RDELADEIANSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTL 1769
Query: 225 -------RELSSKDEMHDEQFKILNKKLR--------------------------DTEAT 305
R + K + +Q + NK+L+ E
Sbjct: 1770 NTELAAERSAAQKSDNARQQLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQ 1829
Query: 306 LEEEQKQRTSLASLKKKLEIENVDLMNQXXXXXXXXXXXXRQIKKHQGTSLNSQREMQEV 485
LE+E K+R + L ++ E + ++ Q Q++K +R+++E
Sbjct: 1830 LEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQLEEA 1889
Query: 486 LNAKNEALKQIKELEKRLRAAESSTNQLIEDLSQ-SERIKR 605
A ++L++ L A + L ++S R++R
Sbjct: 1890 EEEATRANASRRKLQRELDDATEANEGLSREVSTLKNRLRR 1930
>sp|Q27991|MYH10_BOVIN Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy
chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin
heavy chain, type B) (Nonmuscle myosin heavy chain-B)
(NMMHC-B)
Length = 1976
Score = 173 bits (438), Expect = 6e-43
Identities = 95/279 (34%), Positives = 161/279 (57%)
Frame = +3
Query: 18 LNRQLNELVSNKDDVGKNIGSLKNAKIQLENDLENCKKTIEELEEENATLQMNKERIEMQ 197
L + +L+S+KDDVGKN+ L+ +K LE +E + +EELE+E + K R+E+
Sbjct: 1509 LRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVN 1568
Query: 198 LTATKAQLDRELSSKDEMHDEQFKILNKKLRDTEATLEEEQKQRTSLASLKKKLEIENVD 377
+ A KAQ +R+L ++DE ++E+ ++L K++R+ EA LE+E+KQR + KKK+EI+ D
Sbjct: 1569 MQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKD 1628
Query: 378 LMNQXXXXXXXXXXXXRQIKKHQGTSLNSQREMQEVLNAKNEALKQIKELEKRLRAAESS 557
L Q +Q++K Q + QRE++E +++E Q KE EK+L++ E+
Sbjct: 1629 LEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAE 1688
Query: 558 TNQLIEDLSQSERIKRTLISERDDALEEIATLTVNKDTAIADKKRIESNLSALNMDYXXX 737
QL E+L+ SER +R ERD+ +EIA K + +K+R+E+ ++ L +
Sbjct: 1689 ILQLQEELASSERARRHAEQERDELADEIANSASGKSALLDEKRRLEARIAQLEEELEEE 1748
Query: 738 XXXXXXXXDKNKKVTNQLEQVQNELNVERQNATRLENQK 854
D+ +K T Q++ + EL ER A + +N +
Sbjct: 1749 QSNMELLNDRFRKTTLQVDTLNTELAAERSAAQKSDNAR 1787
Score = 55.8 bits (133), Expect = 1e-07
Identities = 54/298 (18%), Positives = 128/298 (42%), Gaps = 30/298 (10%)
Frame = +3
Query: 9 KSLLNRQLN---ELVSNKDDVGKNIGSLKNAKIQLENDLENCKKTIEELEEENATLQMNK 179
K++L QL EL + +++ + + K +LE L + + +EE EE N LQ K
Sbjct: 889 KNILAEQLQAETELFAEAEEMRARLAAKKQ---ELEEILHDLESRVEEEEERNQILQNEK 945
Query: 180 ERIEMQLTATKAQLDRELSSKDEMHDEQF---------------------------KILN 278
++++ + + QLD E ++ ++ E+ K++
Sbjct: 946 KKMQAHIQDLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLME 1005
Query: 279 KKLRDTEATLEEEQKQRTSLASLKKKLEIENVDLMNQXXXXXXXXXXXXRQIKKHQGTSL 458
++ + + L EE+++ +LA ++ K E+ DL ++KK + T
Sbjct: 1006 DRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDL--------------EERLKKEEKT-- 1049
Query: 459 NSQREMQEVLNAKNEALKQIKELEKRLRAAESSTNQLIEDLSQSERIKRTLISERDDALE 638
QE+ AK + + +L+ ++ ++ ++L +++ E + ++ DD
Sbjct: 1050 -----RQELEKAKRKLDGETTDLQDQIAELQAQIDELKIQVAKKEEELQGALARGDDE-- 1102
Query: 639 EIATLTVNKDTAIADKKRIESNLSALNMDYXXXXXXXXXXXDKNKKVTNQLEQVQNEL 812
T++K+ A+ + +++ ++ L D+ + + ++ +LE ++ EL
Sbjct: 1103 -----TLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTEL 1155
Score = 51.6 bits (122), Expect = 3e-06
Identities = 50/227 (22%), Positives = 103/227 (45%), Gaps = 15/227 (6%)
Frame = +3
Query: 9 KSLLNRQLNELVSNKDDVGKNIGSLKNAKIQLENDLENCKKTIEELEEENATLQMNKERI 188
K+ L + L ++ ++ + L+ K + E+ + ++EL + + + ++ R+
Sbjct: 1219 KANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVS--EGDRLRV 1276
Query: 189 EMQLTATKAQ--LDRELSSKDEMHDEQFKI------LNKKLRDTEATLEEEQKQRTSLAS 344
E+ A K Q LD + +E + K L +L+DT+ L+EE +Q+ +L+S
Sbjct: 1277 ELAEKANKLQNELDNVSTLLEEAEKKGIKFAKDAAGLESQLQDTQELLQEETRQKLNLSS 1336
Query: 345 LKKKLEIENVDLMNQXXXXXXXXXXXXRQIKKHQGTSLNSQREMQEVL-------NAKNE 503
++LE E L Q +Q++ Q ++++++ + L AK +
Sbjct: 1337 RIRQLEEERSSLQEQQEEEEEARRSLEKQLQALQAQLTDTKKKVDDDLGTIENLEEAKKK 1396
Query: 504 ALKQIKELEKRLRAAESSTNQLIEDLSQSERIKRTLISERDDALEEI 644
LK ++ L +RL + ++L E+ K L E DD L ++
Sbjct: 1397 LLKDVEVLSQRLEEKALAYDKL-------EKTKTRLQQELDDLLVDL 1436
Score = 50.1 bits (118), Expect = 8e-06
Identities = 62/316 (19%), Positives = 123/316 (38%), Gaps = 35/316 (11%)
Frame = +3
Query: 3 NSKSLLNRQLNELVSNKDDVGKNIGSLKNAKIQLENDLENCKKTIEELEEENATLQMNKE 182
+ + L+ Q+ EL + + + L +L+N+L+N +EE E++ +
Sbjct: 1252 HKRKKLDAQVQELHAKVSEGDRLRVELAEKANKLQNELDNVSTLLEEAEKKGIKFAKDAA 1311
Query: 183 RIEMQLTATK-----------------AQLDRELSSKDEMHDE----------QFKILNK 281
+E QL T+ QL+ E SS E +E Q + L
Sbjct: 1312 GLESQLQDTQELLQEETRQKLNLSSRIRQLEEERSSLQEQQEEEEEARRSLEKQLQALQA 1371
Query: 282 KLRDTEATLEEEQKQRTSLASLKKKLEIENVDLMNQXXXXXXXXXXXXRQIKKHQG---- 449
+L DT+ ++++ +L KKKL +++V++++Q + K
Sbjct: 1372 QLTDTKKKVDDDLGTIENLEEAKKKL-LKDVEVLSQRLEEKALAYDKLEKTKTRLQQELD 1430
Query: 450 ---TSLNSQREMQEVLNAKNEALKQIKELEKRLRAAESSTNQLIEDLSQSERIKR-TLIS 617
L+ QR++ L K + Q+ EK + A + E ++ + K +L
Sbjct: 1431 DLLVDLDHQRQIVSNLEKKQKKFDQLLAEEKNISARYAEERDRAEAEAREKETKALSLAR 1490
Query: 618 ERDDALEEIATLTVNKDTAIADKKRIESNLSALNMDYXXXXXXXXXXXDKNKKVTNQLEQ 797
++ALE AD + + S+ + + + +++ QLE+
Sbjct: 1491 ALEEALEAREEAERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEE 1550
Query: 798 VQNELNVERQNATRLE 845
+++EL RLE
Sbjct: 1551 LEDELQATEDAKLRLE 1566
Score = 38.1 bits (87), Expect = 0.032
Identities = 42/221 (19%), Positives = 83/221 (37%), Gaps = 36/221 (16%)
Frame = +3
Query: 51 KDDVGKNIGSLKNAKIQLENDLENCKKTIEELEEENATLQMNKERIEMQLTATKAQLD-- 224
+D++ I + + K L ++ + I +LEEE Q N E + + T Q+D
Sbjct: 1710 RDELADEIANSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTL 1769
Query: 225 -------RELSSKDEMHDEQFKILNKKLR--------------------------DTEAT 305
R + K + +Q + NK+L+ E
Sbjct: 1770 NTELAAERSAAQKSDNARQQLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQ 1829
Query: 306 LEEEQKQRTSLASLKKKLEIENVDLMNQXXXXXXXXXXXXRQIKKHQGTSLNSQREMQEV 485
LE+E K+R + L ++ E + ++ Q Q++K +R+++E
Sbjct: 1830 LEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQLEEA 1889
Query: 486 LNAKNEALKQIKELEKRLRAAESSTNQLIEDLSQ-SERIKR 605
A ++L++ L A + L ++S R++R
Sbjct: 1890 EEEATRANASRRKLQRELDDATEANEGLSREVSTLKNRLRR 1930
>sp|P35580|MYH10_HUMAN Myosin-10 (Myosin heavy chain, nonmuscle IIb) (Nonmuscle myosin heavy
chain IIb) (NMMHC II-b) (NMMHC-IIB) (Cellular myosin
heavy chain, type B) (Nonmuscle myosin heavy chain-B)
(NMMHC-B)
Length = 1976
Score = 171 bits (432), Expect = 3e-42
Identities = 94/279 (33%), Positives = 160/279 (57%)
Frame = +3
Query: 18 LNRQLNELVSNKDDVGKNIGSLKNAKIQLENDLENCKKTIEELEEENATLQMNKERIEMQ 197
L + +L+S+KDDVGKN+ L+ +K LE +E + +EELE+E + K R+E+
Sbjct: 1509 LRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVN 1568
Query: 198 LTATKAQLDRELSSKDEMHDEQFKILNKKLRDTEATLEEEQKQRTSLASLKKKLEIENVD 377
+ A KAQ +R+L ++DE ++E+ ++L K++R+ EA LE+E+KQR + KKK+EI+ D
Sbjct: 1569 MQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKD 1628
Query: 378 LMNQXXXXXXXXXXXXRQIKKHQGTSLNSQREMQEVLNAKNEALKQIKELEKRLRAAESS 557
L Q +Q++K Q + QRE++E +++E Q KE EK+L++ E+
Sbjct: 1629 LEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAE 1688
Query: 558 TNQLIEDLSQSERIKRTLISERDDALEEIATLTVNKDTAIADKKRIESNLSALNMDYXXX 737
QL E+L+ SER +R ERD+ +EI K + +K+R+E+ ++ L +
Sbjct: 1689 ILQLQEELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEEE 1748
Query: 738 XXXXXXXXDKNKKVTNQLEQVQNELNVERQNATRLENQK 854
D+ +K T Q++ + EL ER A + +N +
Sbjct: 1749 QSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNAR 1787
Score = 57.4 bits (137), Expect = 5e-08
Identities = 54/304 (17%), Positives = 127/304 (41%), Gaps = 30/304 (9%)
Frame = +3
Query: 9 KSLLNRQLN---ELVSNKDDVGKNIGSLKNAKIQLENDLENCKKTIEELEEENATLQMNK 179
K++L QL EL + +++ + + K +LE L + + +EE EE N LQ K
Sbjct: 889 KNILAEQLQAETELFAEAEEMRARLAAKKQ---ELEEILHDLESRVEEEEERNQILQNEK 945
Query: 180 ERIEMQLTATKAQLDRELSSKDEMHDEQF---------------------------KILN 278
++++ + + QLD E ++ ++ E+ K++
Sbjct: 946 KKMQAHIQDLEEQLDEEEGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLME 1005
Query: 279 KKLRDTEATLEEEQKQRTSLASLKKKLEIENVDLMNQXXXXXXXXXXXXRQIKKHQGTSL 458
++ + + L EE+++ +LA ++ K E+ DL + + +K G +
Sbjct: 1006 DRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETT 1065
Query: 459 NSQREMQEVLNAKNEALKQIKELEKRLRAAESSTNQLIEDLSQSERIKRTLISERDDALE 638
+ Q ++ E+ +E Q+ + E+ L+ A + + + + ++ R L ++ + E
Sbjct: 1066 DLQDQIAELQAQIDELKLQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQE 1125
Query: 639 EIATLTVNKDTAIADKKRIESNLSALNMDYXXXXXXXXXXXDKNKKVTNQLEQVQNELNV 818
+ + +++ A K+ + L AL + + K ++ +++ L
Sbjct: 1126 DFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEE 1185
Query: 819 ERQN 830
E +N
Sbjct: 1186 ETKN 1189
Score = 52.4 bits (124), Expect = 2e-06
Identities = 51/243 (20%), Positives = 116/243 (47%), Gaps = 10/243 (4%)
Frame = +3
Query: 9 KSLLNRQLNELVSNKDDVGKNIGSLKNAKIQLENDLENCKKTIEELEEENATLQMNKERI 188
K+ L + L ++ ++ + L+ K + E+ + ++EL + + +R+
Sbjct: 1219 KANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVS----EGDRL 1274
Query: 189 EMQLTATKAQLDRELSSKDEMHDEQFK----------ILNKKLRDTEATLEEEQKQRTSL 338
++L ++L EL + + +E K L +L+DT+ L+EE +Q+ +L
Sbjct: 1275 RVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNL 1334
Query: 339 ASLKKKLEIENVDLMNQXXXXXXXXXXXXRQIKKHQGTSLNSQREMQEVLNAKNEALKQI 518
+S ++LE E L Q +Q+ Q ++++++ + L E+L++
Sbjct: 1335 SSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGT-IESLEEA 1393
Query: 519 KELEKRLRAAESSTNQLIEDLSQSERIKRTLISERDDALEEIATLTVNKDTAIADKKRIE 698
K +K L+ AE+ + +L E +++++T ++ +E+ LTV+ D ++++
Sbjct: 1394 K--KKLLKDAEALSQRLEEKALAYDKLEKT----KNRLQQELDDLTVDLD----HQRQVA 1443
Query: 699 SNL 707
SNL
Sbjct: 1444 SNL 1446
Score = 48.1 bits (113), Expect = 3e-05
Identities = 61/316 (19%), Positives = 120/316 (37%), Gaps = 35/316 (11%)
Frame = +3
Query: 3 NSKSLLNRQLNELVSNKDDVGKNIGSLKNAKIQLENDLENCKKTIEELEEENATLQMNKE 182
+ + L+ Q+ EL + + + L +L+N+L+N +EE E++ +
Sbjct: 1252 HKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAA 1311
Query: 183 RIEMQLTATK-----------------AQLDRELSSKDEMHDE----------QFKILNK 281
+E QL T+ QL+ E +S E +E Q L
Sbjct: 1312 SLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQS 1371
Query: 282 KLRDTEATLEEEQKQRTSLASLKKKLEIENVDLMNQXXXXXXXXXXXXRQIKKH------ 443
+L DT+ ++++ SL KKKL +++ + ++Q + K
Sbjct: 1372 QLADTKKKVDDDLGTIESLEEAKKKL-LKDAEALSQRLEEKALAYDKLEKTKNRLQQELD 1430
Query: 444 -QGTSLNSQREMQEVLNAKNEALKQIKELEKRLRAAESSTNQLIEDLSQSERIKR-TLIS 617
L+ QR++ L K + Q+ EK + A + E ++ + K +L
Sbjct: 1431 DLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLAR 1490
Query: 618 ERDDALEEIATLTVNKDTAIADKKRIESNLSALNMDYXXXXXXXXXXXDKNKKVTNQLEQ 797
++ALE AD + + S+ + + + +++ QLE+
Sbjct: 1491 ALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEE 1550
Query: 798 VQNELNVERQNATRLE 845
+++EL RLE
Sbjct: 1551 LEDELQATEDAKLRLE 1566
Score = 37.4 bits (85), Expect = 0.054
Identities = 42/221 (19%), Positives = 83/221 (37%), Gaps = 36/221 (16%)
Frame = +3
Query: 51 KDDVGKNIGSLKNAKIQLENDLENCKKTIEELEEENATLQMNKERIEMQLTATKAQLD-- 224
+D++ I + + K L ++ + I +LEEE Q N E + + T Q+D
Sbjct: 1710 RDELADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTL 1769
Query: 225 -------RELSSKDEMHDEQFKILNKKLR--------------------------DTEAT 305
R + K + +Q + NK+L+ E
Sbjct: 1770 NAELAAERSAAQKSDNARQQLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQ 1829
Query: 306 LEEEQKQRTSLASLKKKLEIENVDLMNQXXXXXXXXXXXXRQIKKHQGTSLNSQREMQEV 485
LE+E K+R + L ++ E + ++ Q Q++K +R+++E
Sbjct: 1830 LEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQLEEA 1889
Query: 486 LNAKNEALKQIKELEKRLRAAESSTNQLIEDLSQ-SERIKR 605
A ++L++ L A + L ++S R++R
Sbjct: 1890 EEEATRANASRRKLQRELDDATEANEGLSREVSTLKNRLRR 1930
>sp|P35579|MYH9_HUMAN Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy
chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin
heavy chain, type A) (Nonmuscle myosin heavy chain-A)
(NMMHC-A)
Length = 1960
Score = 170 bits (431), Expect = 4e-42
Identities = 94/276 (34%), Positives = 160/276 (57%)
Frame = +3
Query: 27 QLNELVSNKDDVGKNIGSLKNAKIQLENDLENCKKTIEELEEENATLQMNKERIEMQLTA 206
++ +L+S+KDDVGK++ L+ +K LE +E K +EELE+E + K R+E+ L A
Sbjct: 1505 EMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQA 1564
Query: 207 TKAQLDRELSSKDEMHDEQFKILNKKLRDTEATLEEEQKQRTSLASLKKKLEIENVDLMN 386
KAQ +R+L +DE +E+ K L +++R+ EA LE+E+KQR+ + +KKLE++ DL
Sbjct: 1565 MKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLEA 1624
Query: 387 QXXXXXXXXXXXXRQIKKHQGTSLNSQREMQEVLNAKNEALKQIKELEKRLRAAESSTNQ 566
+Q++K Q + RE+ + ++ E L Q KE EK+L++ E+ Q
Sbjct: 1625 HIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQ 1684
Query: 567 LIEDLSQSERIKRTLISERDDALEEIATLTVNKDTAIADKKRIESNLSALNMDYXXXXXX 746
L E+L+ +ER KR ERD+ +EIA + A+ +K+R+E+ ++ L +
Sbjct: 1685 LQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGN 1744
Query: 747 XXXXXDKNKKVTNQLEQVQNELNVERQNATRLENQK 854
D+ KK Q++Q+ +LN+ER +A + EN +
Sbjct: 1745 TELINDRLKKANLQIDQINTDLNLERSHAQKNENAR 1780
Score = 69.3 bits (168), Expect = 1e-11
Identities = 64/293 (21%), Positives = 121/293 (41%), Gaps = 21/293 (7%)
Frame = +3
Query: 9 KSLLNRQLNELVSNKDDVGKNIGSLKNAKIQLENDLENCKKTIEELEEENATLQMNKERI 188
K + + + EL ++ L+ K+ E L+ ++ LE++N L K+ +
Sbjct: 938 KKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEEQIILEDQNCKLAKEKKLL 997
Query: 189 EMQLTATKAQLDRELSSKDEMHDEQFKILNKK---LRDTEATLEEEQKQRTSLASLKKKL 359
E ++ A+ L+ ++E K+ NK + D E L E+KQR L ++KL
Sbjct: 998 EDRI----AEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKL 1053
Query: 360 EIENVDLMNQXXXXXXXXXXXXRQIKKHQGTSLNSQREMQEVLNAKNEALKQIKELEKRL 539
E ++ DL +Q Q+ K + + ++E KN ALK+I+ELE ++
Sbjct: 1054 EGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELESQI 1113
Query: 540 RAAESSTNQLIEDLSQSERIKR-------TLISERDDALEEIAT-----------LTVNK 665
+ +++E+ KR L +E +D L+ A + + K
Sbjct: 1114 SELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVNILK 1173
Query: 666 DTAIADKKRIESNLSALNMDYXXXXXXXXXXXDKNKKVTNQLEQVQNELNVER 824
T + K E+ + + + ++ K+V LE+ + L ER
Sbjct: 1174 KTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENER 1226
Score = 55.5 bits (132), Expect = 2e-07
Identities = 43/213 (20%), Positives = 90/213 (42%)
Frame = +3
Query: 6 SKSLLNRQLNELVSNKDDVGKNIGSLKNAKIQLENDLENCKKTIEELEEENATLQMNKER 185
+K L + EL + + + G ++ + ++E L+ + E E L +
Sbjct: 1218 AKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTK 1277
Query: 186 IEMQLTATKAQLDRELSSKDEMHDEQFKILNKKLRDTEATLEEEQKQRTSLASLKKKLEI 365
++++L L + SK + F L +L+DT+ L+EE +Q+ SL++ K++E
Sbjct: 1278 LQVELDNVTGLLSQS-DSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVED 1336
Query: 366 ENVDLMNQXXXXXXXXXXXXRQIKKHQGTSLNSQREMQEVLNAKNEALKQIKELEKRLRA 545
E Q +QI + +++M++ + A + ++L+K L
Sbjct: 1337 EKNSFREQLEEEEEAKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEG 1396
Query: 546 AESSTNQLIEDLSQSERIKRTLISERDDALEEI 644
+ + + E+ K L E DD L ++
Sbjct: 1397 LSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDL 1429
Score = 55.5 bits (132), Expect = 2e-07
Identities = 60/303 (19%), Positives = 121/303 (39%), Gaps = 21/303 (6%)
Frame = +3
Query: 9 KSLLNRQLNELVSNKDDVGKNIGSLKNAKIQLENDLENCKKTIEELEEENATLQMNKERI 188
K L + L L ++ L+ K +L+ +L++ ++ + L+ +++
Sbjct: 1387 KRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKF 1446
Query: 189 EMQLTATKAQLDRELSSKDEMHDEQFKILNKKLRDTEATLEEEQKQRTSLASLKKKLEIE 368
+ QL A + + + + + + + + + K LEE +Q+ L L K+ E
Sbjct: 1447 D-QLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEAMEQKAELERLNKQFRTE 1505
Query: 369 NVDLMNQXXXXXXXXXXXXRQIKKHQGTSLNSQREMQEVLNAKNEALK-QIKELEKRLRA 545
DLM+ K G S++ + + L + E +K Q++ELE L+A
Sbjct: 1506 MEDLMSS---------------KDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQA 1550
Query: 546 AESSTNQLIEDL---------------SQSERIKRTLISERDDALEEIATLTVNKDTAIA 680
E + +L +L QSE K+ L+ + + E+ + A+A
Sbjct: 1551 TEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAVA 1610
Query: 681 DKKRIESNLSALNMDYXXXXXXXXXXXDKNKKVTNQLEQVQNELNVERQN-----ATRLE 845
+K++E +L L + +K+ Q++ EL+ R + A E
Sbjct: 1611 ARKKLEMDLKDLEAHIDSANKNRDEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKE 1670
Query: 846 NQK 854
N+K
Sbjct: 1671 NEK 1673
Score = 49.7 bits (117), Expect = 1e-05
Identities = 60/284 (21%), Positives = 105/284 (36%), Gaps = 45/284 (15%)
Frame = +3
Query: 138 EELEEENATLQMNKERIEMQLTATKAQLDRELSSKDEMHDEQFKI----------LNKKL 287
++L EN +M E ++ QL A K QL +L ++ E+ E ++ L +
Sbjct: 860 KQLAAENRLTEM--ETLQSQLMAEKLQLQEQLQAETELCAEAEELRARLTAKKQELEEIC 917
Query: 288 RDTEATLEEEQKQRTSLASLK-----------------------------------KKLE 362
D EA +EEE+++ L + K KKLE
Sbjct: 918 HDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLE 977
Query: 363 IENVDLMNQXXXXXXXXXXXXRQIKKHQGTSLNSQREMQEVLNAKNEALKQIKELEKRLR 542
E + L +Q +I + + + + + KN+ I +LE+RLR
Sbjct: 978 EEQIILEDQNCKLAKEKKLLEDRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLR 1037
Query: 543 AAESSTNQLIEDLSQSERIKRTLISERDDALEEIATLTVNKDTAIADKKRIESNLSALNM 722
E +L E+ +R L + D ++IA L + E L A
Sbjct: 1038 REEKQRQEL-------EKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALA 1090
Query: 723 DYXXXXXXXXXXXDKNKKVTNQLEQVQNELNVERQNATRLENQK 854
K +++ +Q+ ++Q +L ER + + E QK
Sbjct: 1091 RVEEEAAQKNMALKKIRELESQISELQEDLESERASRNKAEKQK 1134
Score = 43.1 bits (100), Expect = 0.001
Identities = 49/221 (22%), Positives = 92/221 (41%), Gaps = 16/221 (7%)
Frame = +3
Query: 24 RQLNELVSNKDDVGKNIGSLKNAKIQLENDLENCKKTIEELEEENATLQMNKERIEMQLT 203
R + +D++ I + + + I +LEEE Q N E I +L
Sbjct: 1694 RAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIAQLEEELEEEQGNTELINDRLK 1753
Query: 204 ATKAQLD---------RELSSKDEMHDEQFKILNK----KLRDTEATLEEEQKQRTSLAS 344
Q+D R + K+E +Q + NK KL++ E T+ + K + S+ +
Sbjct: 1754 KANLQIDQINTDLNLERSHAQKNENARQQLERQNKELKVKLQEMEGTV--KSKYKASITA 1811
Query: 345 LKKKLEIENVDLMNQXXXXXXXXXXXXRQIKKHQGTSL---NSQREMQEVLNAKNEALKQ 515
L+ K+ L N+ R KK + L + +R ++ + ++A +
Sbjct: 1812 LEAKIAQLEEQLDNETKERQAACKQVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTR 1871
Query: 516 IKELEKRLRAAESSTNQLIEDLSQSERIKRTLISERDDALE 638
+K+L+++L AE E+ ++ +R L E +DA E
Sbjct: 1872 LKQLKRQLEEAE-------EEAQRANASRRKLQRELEDATE 1905
Score = 33.5 bits (75), Expect = 0.78
Identities = 19/75 (25%), Positives = 39/75 (52%), Gaps = 3/75 (4%)
Frame = +3
Query: 24 RQLNELVSNKDDVGKNIGSLKNAKIQLENDLENCKKTIEELEEENATLQMNKERIEMQL- 200
++L +++ DD +N K+ + L+ K+ +EE EEE ++ +++ +L
Sbjct: 1842 KKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELE 1901
Query: 201 --TATKAQLDRELSS 239
T T ++RE+SS
Sbjct: 1902 DATETADAMNREVSS 1916
>sp|Q99105|MYSU_RABIT Myosin heavy chain, embryonic smooth muscle isoform
Length = 501
Score = 170 bits (431), Expect = 4e-42
Identities = 94/279 (33%), Positives = 158/279 (56%)
Frame = +3
Query: 18 LNRQLNELVSNKDDVGKNIGSLKNAKIQLENDLENCKKTIEELEEENATLQMNKERIEMQ 197
L + +L+S+KDDVGKN+ L+ +K LE +E + +EELE+E + K R+E+
Sbjct: 34 LRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVN 93
Query: 198 LTATKAQLDRELSSKDEMHDEQFKILNKKLRDTEATLEEEQKQRTSLASLKKKLEIENVD 377
A KAQ +R+L ++DE +E+ ++L K++R+ EA LE+E+KQR + KKK+EI+ D
Sbjct: 94 TQAMKAQFERDLQARDEQSEEKKRLLTKQVRELEAELEDERKQRALAVASKKKMEIDLKD 153
Query: 378 LMNQXXXXXXXXXXXXRQIKKHQGTSLNSQREMQEVLNAKNEALKQIKELEKRLRAAESS 557
L Q +Q+++ Q + QRE++E +++E Q KE EK+L++ E+
Sbjct: 154 LEAQIEAANKARERRVKQLRRLQAQMKDYQRELEEARGSRDEIFAQSKESEKKLKSLEAE 213
Query: 558 TNQLIEDLSQSERIKRTLISERDDALEEIATLTVNKDTAIADKKRIESNLSALNMDYXXX 737
QL E+L+ SER +R ERD+ +EIA K + +K+R+E+ + L +
Sbjct: 214 ILQLQEELASSERARRHAEQERDELADEIANSASGKSALLDEKRRLEARMRQLEEELEEE 273
Query: 738 XXXXXXXXDKNKKVTNQLEQVQNELNVERQNATRLENQK 854
D+ +K T Q++ + EL ER A + +N +
Sbjct: 274 QSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNAR 312
Score = 37.4 bits (85), Expect = 0.054
Identities = 43/212 (20%), Positives = 85/212 (40%), Gaps = 33/212 (15%)
Frame = +3
Query: 69 NIGSLKNAKIQLENDLE-NCKKTIEELEEENATLQMNKERIE---MQLTATKAQL--DRE 230
N S K+A + + LE ++ EELEEE + +++ +R +Q+ A+L +R
Sbjct: 244 NSASGKSALLDEKRRLEARMRQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERS 303
Query: 231 LSSKDEMHDEQFKILNKKLR--------------------------DTEATLEEEQKQRT 332
+ K + +Q + NK L+ E LE+E K+R
Sbjct: 304 AAQKSDNARQQLERQNKDLKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERA 363
Query: 333 SLASLKKKLEIENVDLMNQXXXXXXXXXXXXRQIKKHQGTSLNSQREMQEVLNAKNEALK 512
+ L ++ E + ++ Q Q++K +R+++E A
Sbjct: 364 AANKLVRRTEKKLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANA 423
Query: 513 QIKELEKRLRAAESSTNQLIEDLSQ-SERIKR 605
++L++ L A + L ++S R++R
Sbjct: 424 SRRKLQRELDDATEANEGLSREVSTLKNRLRR 455
>sp|Q8VDD5|MYH9_MOUSE Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy
chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin
heavy chain, type A) (Nonmuscle myosin heavy chain-A)
(NMMHC-A)
Length = 1960
Score = 170 bits (430), Expect = 5e-42
Identities = 94/276 (34%), Positives = 160/276 (57%)
Frame = +3
Query: 27 QLNELVSNKDDVGKNIGSLKNAKIQLENDLENCKKTIEELEEENATLQMNKERIEMQLTA 206
++ +L+S+KDDVGK++ L+ +K LE +E K +EELE+E + K R+E+ L A
Sbjct: 1505 EMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNLQA 1564
Query: 207 TKAQLDRELSSKDEMHDEQFKILNKKLRDTEATLEEEQKQRTSLASLKKKLEIENVDLMN 386
KAQ +R+L +DE +E+ K L +++R+ EA LE+E+KQR+ + +KKLE++ DL
Sbjct: 1565 MKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMAMAARKKLEMDLKDLEA 1624
Query: 387 QXXXXXXXXXXXXRQIKKHQGTSLNSQREMQEVLNAKNEALKQIKELEKRLRAAESSTNQ 566
+Q++K Q + RE+ + ++ E L Q KE EK+L++ E+ Q
Sbjct: 1625 HIDTANKNREEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKENEKKLKSMEAEMIQ 1684
Query: 567 LIEDLSQSERIKRTLISERDDALEEIATLTVNKDTAIADKKRIESNLSALNMDYXXXXXX 746
L E+L+ +ER KR ERD+ +EIA + A+ +K+R+E+ ++ L +
Sbjct: 1685 LQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEKRRLEARIALLEEELEEEQGN 1744
Query: 747 XXXXXDKNKKVTNQLEQVQNELNVERQNATRLENQK 854
D+ KK Q++Q+ +LN+ER +A + EN +
Sbjct: 1745 TELINDRLKKANLQIDQINTDLNLERSHAQKNENAR 1780
Score = 66.6 bits (161), Expect = 8e-11
Identities = 63/293 (21%), Positives = 121/293 (41%), Gaps = 21/293 (7%)
Frame = +3
Query: 9 KSLLNRQLNELVSNKDDVGKNIGSLKNAKIQLENDLENCKKTIEELEEENATLQMNKERI 188
K + + + EL ++ L+ K+ E L+ ++ +E++N L K+ +
Sbjct: 938 KKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEDQIIMEDQNCKLAKEKKLL 997
Query: 189 EMQLTATKAQLDRELSSKDEMHDEQFKILNKK---LRDTEATLEEEQKQRTSLASLKKKL 359
E ++ A+ L ++E K+ NK + D E L E+KQR L ++KL
Sbjct: 998 EDRV----AEFTTNLMEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKL 1053
Query: 360 EIENVDLMNQXXXXXXXXXXXXRQIKKHQGTSLNSQREMQEVLNAKNEALKQIKELEKRL 539
E ++ DL +Q Q+ K + + ++E KN ALK+I+ELE ++
Sbjct: 1054 EGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELETQI 1113
Query: 540 RAAESSTNQLIEDLSQSERIKR-------TLISERDDALEEIAT-----------LTVNK 665
+ +++E+ KR L +E +D L+ A +++ K
Sbjct: 1114 SELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVSILK 1173
Query: 666 DTAIADKKRIESNLSALNMDYXXXXXXXXXXXDKNKKVTNQLEQVQNELNVER 824
T + K E+ + + + ++ K+V LE+ + L ER
Sbjct: 1174 KTLEDEAKTHEAQIQEMRQKHSQAVEELADQLEQTKRVKATLEKAKQTLENER 1226
Score = 59.7 bits (143), Expect = 1e-08
Identities = 57/271 (21%), Positives = 112/271 (41%), Gaps = 1/271 (0%)
Frame = +3
Query: 18 LNRQLNELVSNKDDVGKNIGSLKNAKIQLENDLENCKKTIEELEEENATLQMNKERIEMQ 197
L+ Q+ ++ +D + + + AK +L+ DLE + +EE L+ K R++ +
Sbjct: 1362 LHAQVTDMKKKMEDGVGCLETAEEAKRRLQKDLEGLSQRLEEKVAAYDKLEKTKTRLQQE 1421
Query: 198 LTATKAQLDRELSSKDEMHDEQFKILNKKLRDTEATLEEEQKQRTSLASLKKKLEIENVD 377
L LD + S L KK + + L EE+ A + + E E +
Sbjct: 1422 LDDLLVDLDHQRQSVSN--------LEKKQKKFDQLLAEEKTISAKYAEERDRAEAEARE 1473
Query: 378 LMNQXXXXXXXXXXXXRQIKKHQGTSLNSQREMQEVLNAKNEALKQIKELEKRLRAAESS 557
+ Q + + + + EM++++++K++ K + ELEK RA E
Sbjct: 1474 KETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQ 1533
Query: 558 TNQLIEDLSQSERIKRTLISERDDALEEIATLTVNKDTAIADKKRIESNLSALNMDY-XX 734
++ +T + E +D L+ +D K R+E NL A+ +
Sbjct: 1534 VEEM-----------KTQLEELEDELQ------ATEDA----KLRLEVNLQAMKAQFERD 1572
Query: 735 XXXXXXXXXDKNKKVTNQLEQVQNELNVERQ 827
+K K++ Q+ +++ EL ER+
Sbjct: 1573 LQGRDEQSEEKKKQLVRQVREMEAELEDERK 1603
Score = 57.4 bits (137), Expect = 5e-08
Identities = 43/213 (20%), Positives = 90/213 (42%)
Frame = +3
Query: 6 SKSLLNRQLNELVSNKDDVGKNIGSLKNAKIQLENDLENCKKTIEELEEENATLQMNKER 185
+K L + EL + + + G ++ + ++E L+ + E E L +
Sbjct: 1218 AKQTLENERGELANEVKALLQGKGDSEHKRKKVEAQLQELQVKFSEGERVRTELADKVTK 1277
Query: 186 IEMQLTATKAQLDRELSSKDEMHDEQFKILNKKLRDTEATLEEEQKQRTSLASLKKKLEI 365
++++L + L + SK + F L +L+DT+ L+EE +Q+ SL++ K++E
Sbjct: 1278 LQVELDSVTGLLSQS-DSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQMED 1336
Query: 366 ENVDLMNQXXXXXXXXXXXXRQIKKHQGTSLNSQREMQEVLNAKNEALKQIKELEKRLRA 545
E Q +QI + +++M++ + A + + L+K L
Sbjct: 1337 EKNSFREQLEEEEEAKRNLEKQIATLHAQVTDMKKKMEDGVGCLETAEEAKRRLQKDLEG 1396
Query: 546 AESSTNQLIEDLSQSERIKRTLISERDDALEEI 644
+ + + E+ K L E DD L ++
Sbjct: 1397 LSQRLEEKVAAYDKLEKTKTRLQQELDDLLVDL 1429
Score = 51.2 bits (121), Expect = 4e-06
Identities = 70/305 (22%), Positives = 132/305 (43%), Gaps = 22/305 (7%)
Frame = +3
Query: 6 SKSLLNRQLNELVSNKDDVGKN----IGSLKNAKIQLEN---DLENCKKTIEEL-----E 149
++ L L +L ++ D KN I L+ + Q+++ +L++ + + EE+ E
Sbjct: 1611 ARKKLEMDLKDLEAHIDTANKNREEAIKQLRKLQAQMKDCMRELDDTRASREEILAQAKE 1670
Query: 150 EENATLQMNKERIEMQ--LTATKAQLDRELSSKDEMHDEQFKILNKKLRDTEATLEEEQK 323
E M E I++Q L A + + +DE+ DE I N + A LEE+++
Sbjct: 1671 NEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADE---IANSSGKGALA-LEEKRR 1726
Query: 324 QRTSLASLKKKLEIE--NVDLMNQXXXXXXXXXXXXRQIKKHQGTSLNSQRE-MQEVLNA 494
+A L+++LE E N +L+N T LN +R Q+ NA
Sbjct: 1727 LEARIALLEEELEEEQGNTELINDRLKKANLQIDQIN-------TDLNLERSHAQKNENA 1779
Query: 495 KNEALKQIKELEKRLRAAESSTNQLIEDLSQSERIKRTLISERDDALEEIATLTVNKDTA 674
+ + +Q KEL+ +L+ ES+ S+ + L ++ E++ T + A
Sbjct: 1780 RQQLERQNKELKAKLQEMESAVK------SKYKASIAALEAKIAQLEEQLDNETKERQAA 1833
Query: 675 IADKKRIESNLSALNMDYXXXXXXXXXXXDKNKKVTNQLEQVQNEL-----NVERQNATR 839
+R E L + + D+ K + +L+Q++ +L +R NA+R
Sbjct: 1834 SKQVRRTEKKLKDVLLQVEDERRNAEQFKDQADKASTRLKQLKRQLEEAEEEAQRANASR 1893
Query: 840 LENQK 854
+ Q+
Sbjct: 1894 RKLQR 1898
Score = 50.8 bits (120), Expect = 5e-06
Identities = 59/307 (19%), Positives = 120/307 (39%), Gaps = 28/307 (9%)
Frame = +3
Query: 18 LNRQLNELVSNKDDVGKNIGSLK----NAKIQLENDLENCKKTIEELEEENATLQMNKER 185
L + +L + D+ I L+ K+QL E + + +EEE A M ++
Sbjct: 1046 LEKTRRKLEGDSTDLSDQIAELQAQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKK 1105
Query: 186 I---EMQLTATKAQLDRELSSKDEMHD------EQFKILNKKLRDT----EATLEEEQKQ 326
I E Q++ + L+ E +S+++ E+ + L +L DT A E K+
Sbjct: 1106 IRELETQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKR 1165
Query: 327 RTSLASLKKKLEIE----NVDLMNQXXXXXXXXXXXXRQIKKHQGTSLNSQREMQEVLNA 494
++ LKK LE E + Q+++ + ++ Q + N
Sbjct: 1166 EQEVSILKKTLEDEAKTHEAQIQEMRQKHSQAVEELADQLEQTKRVKATLEKAKQTLENE 1225
Query: 495 KNEALKQIKEL-------EKRLRAAESSTNQLIEDLSQSERIKRTLISERDDALEEIATL 653
+ E ++K L E + + E+ +L S+ ER++ L + E+ ++
Sbjct: 1226 RGELANEVKALLQGKGDSEHKRKKVEAQLQELQVKFSEGERVRTELADKVTKLQVELDSV 1285
Query: 654 TVNKDTAIADKKRIESNLSALNMDYXXXXXXXXXXXDKNKKVTNQLEQVQNELNVERQNA 833
T + + ++ + SAL + ++ +L+Q+++E N R+
Sbjct: 1286 TGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQMEDEKNSFREQL 1345
Query: 834 TRLENQK 854
E K
Sbjct: 1346 EEEEEAK 1352
Score = 49.7 bits (117), Expect = 1e-05
Identities = 61/306 (19%), Positives = 113/306 (36%), Gaps = 45/306 (14%)
Frame = +3
Query: 72 IGSLKNAKIQLENDLENCKKTIEELEEENATLQMNKERIEMQLTATKAQLDRELSSKDEM 251
+ S+++ L + E K + L EN +M E ++ QL A K QL +L ++ E+
Sbjct: 838 LNSIRHEDELLAKEAELTKVREKHLAAENRLTEM--ETMQSQLMAEKLQLQEQLQAETEL 895
Query: 252 HDEQFKI----------LNKKLRDTEATLEEEQKQRTSLASLK----------------- 350
E ++ L + D EA +EEE+++ L + K
Sbjct: 896 CAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQYLQAEKKKMQQNIQELEEQLEEE 955
Query: 351 ------------------KKLEIENVDLMNQXXXXXXXXXXXXRQIKKHQGTSLNSQREM 476
KKLE + + + +Q ++ + + + +
Sbjct: 956 ESARQKLQLEKVTTEAKLKKLEEDQIIMEDQNCKLAKEKKLLEDRVAEFTTNLMEEEEKS 1015
Query: 477 QEVLNAKNEALKQIKELEKRLRAAESSTNQLIEDLSQSERIKRTLISERDDALEEIATLT 656
+ + KN+ I +LE+RLR E +L E+ +R L + D ++IA L
Sbjct: 1016 KSLAKLKNKHEAMITDLEERLRREEKQRQEL-------EKTRRKLEGDSTDLSDQIAELQ 1068
Query: 657 VNKDTAIADKKRIESNLSALNMDYXXXXXXXXXXXDKNKKVTNQLEQVQNELNVERQNAT 836
+ E L A K +++ Q+ ++Q +L ER +
Sbjct: 1069 AQIAELKMQLAKKEEELQAALARVEEEAAQKNMALKKIRELETQISELQEDLESERASRN 1128
Query: 837 RLENQK 854
+ E QK
Sbjct: 1129 KAEKQK 1134
Score = 32.3 bits (72), Expect = 1.7
Identities = 18/75 (24%), Positives = 39/75 (52%), Gaps = 3/75 (4%)
Frame = +3
Query: 24 RQLNELVSNKDDVGKNIGSLKNAKIQLENDLENCKKTIEELEEENATLQMNKERIEMQL- 200
++L +++ +D +N K+ + L+ K+ +EE EEE ++ +++ +L
Sbjct: 1842 KKLKDVLLQVEDERRNAEQFKDQADKASTRLKQLKRQLEEAEEEAQRANASRRKLQRELE 1901
Query: 201 --TATKAQLDRELSS 239
T T ++RE+SS
Sbjct: 1902 DATETADAMNREVSS 1916
>sp|P14105|MYH9_CHICK Myosin-9 (Myosin heavy chain, nonmuscle IIa) (Nonmuscle myosin heavy
chain IIa) (NMMHC II-a) (NMMHC-IIA) (Cellular myosin
heavy chain, type A) (Nonmuscle myosin heavy chain-A)
(NMMHC-A)
Length = 1959
Score = 169 bits (429), Expect = 7e-42
Identities = 94/276 (34%), Positives = 159/276 (57%)
Frame = +3
Query: 27 QLNELVSNKDDVGKNIGSLKNAKIQLENDLENCKKTIEELEEENATLQMNKERIEMQLTA 206
++ +L+S+KDDVGK++ L+ AK LE +E K +EELE+E + K R+E+ A
Sbjct: 1505 EMEDLMSSKDDVGKSVHELEKAKRALEQQVEEMKTQLEELEDELQATEDAKLRLEVNQQA 1564
Query: 207 TKAQLDRELSSKDEMHDEQFKILNKKLRDTEATLEEEQKQRTSLASLKKKLEIENVDLMN 386
KAQ DR+L +DE ++E+ K L +++R+ E LE+E+KQR+ + +KKLE++ DL +
Sbjct: 1565 MKAQFDRDLLGRDEQNEEKRKQLIRQVREMEVELEDERKQRSIAVAARKKLELDLKDLES 1624
Query: 387 QXXXXXXXXXXXXRQIKKHQGTSLNSQREMQEVLNAKNEALKQIKELEKRLRAAESSTNQ 566
+ ++K Q + RE+++ ++ E L Q KE EK+L++ E+ Q
Sbjct: 1625 HIDTANKNRDEAIKHVRKLQAQMKDYMRELEDTRTSREEILAQAKENEKKLKSMEAEMIQ 1684
Query: 567 LIEDLSQSERIKRTLISERDDALEEIATLTVNKDTAIADKKRIESNLSALNMDYXXXXXX 746
L E+L+ +ER KR ERD+ +EIA + A+ +K+R+E+ ++ L +
Sbjct: 1685 LQEELAAAERAKRQAQQERDELADEIANSSGKGALAMEEKRRLEARIAQLEEELEEEQGN 1744
Query: 747 XXXXXDKNKKVTNQLEQVQNELNVERQNATRLENQK 854
D+ KK Q++Q+ +LN ER NA + EN +
Sbjct: 1745 TEIINDRLKKANLQIDQMNADLNAERSNAQKNENAR 1780
Score = 71.2 bits (173), Expect = 3e-12
Identities = 65/293 (22%), Positives = 123/293 (41%), Gaps = 21/293 (7%)
Frame = +3
Query: 9 KSLLNRQLNELVSNKDDVGKNIGSLKNAKIQLENDLENCKKTIEELEEENATLQMNKERI 188
K + + + EL ++ L+ K+ E L+ ++ + LE++N L K+ +
Sbjct: 938 KKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLEEDVIVLEDQNLKLAKEKKLL 997
Query: 189 EMQLTATKAQLDRELSSKDEMHDEQFKILNKK---LRDTEATLEEEQKQRTSLASLKKKL 359
E +++ + L+ ++E K+ NK + D E L E+KQR L ++KL
Sbjct: 998 EDRMS----EFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLRREEKQRQELEKTRRKL 1053
Query: 360 EIENVDLMNQXXXXXXXXXXXXRQIKKHQGTSLNSQREMQEVLNAKNEALKQIKELEKRL 539
E ++ DL +Q Q+ K + + ++E KN ALK+I+ELE ++
Sbjct: 1054 EGDSSDLHDQIAELQAQIAELKIQLSKKEEELQAALARVEEEAAQKNMALKKIRELESQI 1113
Query: 540 RAAESSTNQLIEDLSQSERIKR-------TLISERDDALEEIAT-----------LTVNK 665
+ +++E+ KR L +E +D L+ A +TV K
Sbjct: 1114 TELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVTVLK 1173
Query: 666 DTAIADKKRIESNLSALNMDYXXXXXXXXXXXDKNKKVTNQLEQVQNELNVER 824
T + K E+ + + + ++ K+V LE+ + L ER
Sbjct: 1174 KTLEDEAKTHEAQIQEMRQKHSQAIEELAEQLEQTKRVKANLEKAKQALESER 1226
Score = 51.2 bits (121), Expect = 4e-06
Identities = 45/213 (21%), Positives = 89/213 (41%), Gaps = 6/213 (2%)
Frame = +3
Query: 9 KSLLNRQLNELVSNKDDVGKNIGSLKNAKIQLENDLENCKKTIEELEEENATLQMNKERI 188
K+ L + L S + ++ + L K E+ + ++EL+ + + K +
Sbjct: 1212 KANLEKAKQALESERAELSNEVKVLLQGKGDAEHKRKKVDAQLQELQVKFTEGERVKTEL 1271
Query: 189 EMQLTATKAQLDR------ELSSKDEMHDEQFKILNKKLRDTEATLEEEQKQRTSLASLK 350
++ + +LD + SK + F L +L+DT+ L+EE + + S ++
Sbjct: 1272 AERVNKLQVELDNVTGLLNQSDSKSIKLAKDFSALESQLQDTQELLQEETRLKLSFSTKL 1331
Query: 351 KKLEIENVDLMNQXXXXXXXXXXXXRQIKKHQGTSLNSQREMQEVLNAKNEALKQIKELE 530
K+ E E L Q +QI Q ++ ++++M + L A + K+L+
Sbjct: 1332 KQTEDEKNALKEQLEEEEEAKRNLEKQISVLQQQAVEARKKMDDGLGCLEIAEEAKKKLQ 1391
Query: 531 KRLRAAESSTNQLIEDLSQSERIKRTLISERDD 629
K L + + I + E+ K L E DD
Sbjct: 1392 KDLESLTQRYEEKIAAYDKLEKTKTRLQQELDD 1424
Score = 50.4 bits (119), Expect = 6e-06
Identities = 63/284 (22%), Positives = 119/284 (41%), Gaps = 10/284 (3%)
Frame = +3
Query: 18 LNRQLNELVSNKDDVGKNIGSLKNAKIQLENDLENCKKTIEEL-----EEENATLQMNKE 182
L ++ N+D+ K++ L+ +LE+ + + EE+ E E M E
Sbjct: 1622 LESHIDTANKNRDEAIKHVRKLQAQMKDYMRELEDTRTSREEILAQAKENEKKLKSMEAE 1681
Query: 183 RIEMQ--LTATKAQLDRELSSKDEMHDEQFKILNKKLRDTEATLEEEQKQRTSLASLKKK 356
I++Q L A + + +DE+ DE I N + A +EE+++ +A L+++
Sbjct: 1682 MIQLQEELAAAERAKRQAQQERDELADE---IANSSGKGALA-MEEKRRLEARIAQLEEE 1737
Query: 357 LEIE--NVDLMNQXXXXXXXXXXXXRQIKKHQGTSLNSQR-EMQEVLNAKNEALKQIKEL 527
LE E N +++N QI + LN++R Q+ NA+ + +Q KEL
Sbjct: 1738 LEEEQGNTEIINDRLKKANL------QIDQ-MNADLNAERSNAQKNENARQQMERQNKEL 1790
Query: 528 EKRLRAAESSTNQLIEDLSQSERIKRTLISERDDALEEIATLTVNKDTAIADKKRIESNL 707
+ +L+ ES+ + + K + E+ D T + A +R E L
Sbjct: 1791 KLKLQEMESAVKSKYKATITALEAKIVQLEEQLD------METKERQAASKQVRRAEKKL 1844
Query: 708 SALNMDYXXXXXXXXXXXDKNKKVTNQLEQVQNELNVERQNATR 839
+ + D+ K +L+Q++ +L + A R
Sbjct: 1845 KDILLQVDDERRNAEQFKDQADKANMRLKQLKRQLEEAEEEAQR 1888
Score = 50.1 bits (118), Expect = 8e-06
Identities = 59/304 (19%), Positives = 121/304 (39%), Gaps = 21/304 (6%)
Frame = +3
Query: 6 SKSLLNRQLNELVSNKDDVGKNIGSLKNAKIQLENDLENCKKTIEELEEENATLQMNKER 185
+K L + L L ++ L+ K +L+ +L++ ++ + + L+ +++
Sbjct: 1386 AKKKLQKDLESLTQRYEEKIAAYDKLEKTKTRLQQELDDIAVDLDHQRQTVSNLEKKQKK 1445
Query: 186 IEMQLTATKAQLDRELSSKDEMHDEQFKILNKKLRDTEATLEEEQKQRTSLASLKKKLEI 365
+ QL A + + + + + + + + + K LEE +Q+ L + K+
Sbjct: 1446 FD-QLLAEEKNISAKYAEERDRAEAEAREKETKALSLARALEEAIEQKAELERVNKQFRT 1504
Query: 366 ENVDLMNQXXXXXXXXXXXXRQIKKHQGTSLNSQREMQEVLNAKNEALK-QIKELEKRLR 542
E DLM+ K G S++ + + L + E +K Q++ELE L+
Sbjct: 1505 EMEDLMSS---------------KDDVGKSVHELEKAKRALEQQVEEMKTQLEELEDELQ 1549
Query: 543 AAESS-----TNQ----------LIEDLSQSERIKRTLISERDDALEEIATLTVNKDTAI 677
A E + NQ L+ Q+E ++ LI + + E+ + A+
Sbjct: 1550 ATEDAKLRLEVNQQAMKAQFDRDLLGRDEQNEEKRKQLIRQVREMEVELEDERKQRSIAV 1609
Query: 678 ADKKRIESNLSALNMDYXXXXXXXXXXXDKNKKVTNQLEQVQNELNVERQN-----ATRL 842
A +K++E +L L +K+ Q++ EL R + A
Sbjct: 1610 AARKKLELDLKDLESHIDTANKNRDEAIKHVRKLQAQMKDYMRELEDTRTSREEILAQAK 1669
Query: 843 ENQK 854
EN+K
Sbjct: 1670 ENEK 1673
Score = 48.5 bits (114), Expect = 2e-05
Identities = 58/292 (19%), Positives = 117/292 (40%), Gaps = 25/292 (8%)
Frame = +3
Query: 54 DDVGKNIGSLKNAKIQLENDLENCKKTIEELEEENATLQMNKERI---EMQLTATKAQLD 224
D + + + KIQL E + + +EEE A M ++I E Q+T + L+
Sbjct: 1062 DQIAELQAQIAELKIQLSKKEEELQAALARVEEEAAQKNMALKKIRELESQITELQEDLE 1121
Query: 225 RELSSKDEMHD------EQFKILNKKLRDT----EATLEEEQKQRTSLASLKKKLEIE-- 368
E +S+++ E+ + L +L DT A E K+ + LKK LE E
Sbjct: 1122 SERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVTVLKKTLEDEAK 1181
Query: 369 --NVDLMNQXXXXXXXXXXXXRQIKKHQGTSLNSQREMQEVLNAKNEALKQIKEL----- 527
+ Q+++ + N ++ Q + + + E ++K L
Sbjct: 1182 THEAQIQEMRQKHSQAIEELAEQLEQTKRVKANLEKAKQALESERAELSNEVKVLLQGKG 1241
Query: 528 --EKRLRAAESSTNQLIEDLSQSERIKRTLISERDDALE-EIATLTVNKDTAIADKKRIE 698
E + + ++ +L ++ ER+K T ++ER + L+ E+ +T + + + ++
Sbjct: 1242 DAEHKRKKVDAQLQELQVKFTEGERVK-TELAERVNKLQVELDNVTGLLNQSDSKSIKLA 1300
Query: 699 SNLSALNMDYXXXXXXXXXXXDKNKKVTNQLEQVQNELNVERQNATRLENQK 854
+ SAL + +L+Q ++E N ++ E K
Sbjct: 1301 KDFSALESQLQDTQELLQEETRLKLSFSTKLKQTEDEKNALKEQLEEEEEAK 1352
Score = 46.2 bits (108), Expect = 1e-04
Identities = 60/284 (21%), Positives = 106/284 (37%), Gaps = 45/284 (15%)
Frame = +3
Query: 138 EELEEENATLQMNKERIEMQLTATKAQLDRELSSKDEMHDEQFKI----------LNKKL 287
++L EN +M E + QL A K QL +L ++ E+ E +I L +
Sbjct: 860 KQLAAENRLSEM--ETFQAQLMAEKMQLQEQLQAEAELCAEAEEIRARLTAKKQELEEIC 917
Query: 288 RDTEATLEEEQKQRTSLASLKKKLEIENVDLMNQXXXXXXXXXXXXRQ------------ 431
D EA +EEE+++ L + KKK++ +L Q +
Sbjct: 918 HDLEARVEEEEERCQHLQAEKKKMQQNIQELEEQLEEEESARQKLQLEKVTTEAKLKKLE 977
Query: 432 ----IKKHQGTSLNSQREMQE-------------------VLNAKNEALKQIKELEKRLR 542
+ + Q L ++++ E + KN+ I +LE+RLR
Sbjct: 978 EDVIVLEDQNLKLAKEKKLLEDRMSEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEERLR 1037
Query: 543 AAESSTNQLIEDLSQSERIKRTLISERDDALEEIATLTVNKDTAIADKKRIESNLSALNM 722
E +L E+ +R L + D ++IA L + E L A
Sbjct: 1038 REEKQRQEL-------EKTRRKLEGDSSDLHDQIAELQAQIAELKIQLSKKEEELQAALA 1090
Query: 723 DYXXXXXXXXXXXDKNKKVTNQLEQVQNELNVERQNATRLENQK 854
K +++ +Q+ ++Q +L ER + + E QK
Sbjct: 1091 RVEEEAAQKNMALKKIRELESQITELQEDLESERASRNKAEKQK 1134
Score = 38.9 bits (89), Expect = 0.019
Identities = 49/219 (22%), Positives = 85/219 (38%), Gaps = 14/219 (6%)
Frame = +3
Query: 24 RQLNELVSNKDDVGKNIGSLKNAKIQLENDLENCKKTIEELEEENATLQMNKERIEMQLT 203
R + +D++ I + + + I +LEEE Q N E I +L
Sbjct: 1694 RAKRQAQQERDELADEIANSSGKGALAMEEKRRLEARIAQLEEELEEEQGNTEIINDRLK 1753
Query: 204 ATKAQLD---------RELSSKDEMHDEQFKILNK--KLRDTEATLEEEQKQRTSLASLK 350
Q+D R + K+E +Q + NK KL+ E + K + ++ +L+
Sbjct: 1754 KANLQIDQMNADLNAERSNAQKNENARQQMERQNKELKLKLQEMESAVKSKYKATITALE 1813
Query: 351 KKLEIENVDLMNQXXXXXXXXXXXXRQIKKHQGTSLNSQREMQEVLNAKNEALK---QIK 521
K+ L + R KK + L E + K++A K ++K
Sbjct: 1814 AKIVQLEEQLDMETKERQAASKQVRRAEKKLKDILLQVDDERRNAEQFKDQADKANMRLK 1873
Query: 522 ELEKRLRAAESSTNQLIEDLSQSERIKRTLISERDDALE 638
+L+++L AE +Q ++R L E DDA E
Sbjct: 1874 QLKRQLEEAEEE--------AQRANVRRKLQRELDDATE 1904
Score = 35.4 bits (80), Expect = 0.21
Identities = 30/178 (16%), Positives = 72/178 (40%), Gaps = 1/178 (0%)
Frame = +3
Query: 21 NRQLNELVSNKDDVGKNIGSLKNAKIQLENDLENCKKTIEELEEE-NATLQMNKERIEMQ 197
N Q++++ ++ + N +NA+ Q+E + K ++E+E + + +E +
Sbjct: 1756 NLQIDQMNADLNAERSNAQKNENARQQMERQNKELKLKLQEMESAVKSKYKATITALEAK 1815
Query: 198 LTATKAQLDRELSSKDEMHDEQFKILNKKLRDTEATLEEEQKQRTSLASLKKKLEIENVD 377
+ + QLD E + + +Q + KKL+D +++E++ K +
Sbjct: 1816 IVQLEEQLDMETKER-QAASKQVRRAEKKLKDILLQVDDERRNAEQFKDQADKANMRLKQ 1874
Query: 378 LMNQXXXXXXXXXXXXRQIKKHQGTSLNSQREMQEVLNAKNEALKQIKELEKRLRAAE 551
L Q + + QRE+ + + +++ L+ +LR +
Sbjct: 1875 LKRQ--------LEEAEEEAQRANVRRKLQRELDDATETADAMNREVSSLKSKLRRGD 1924
Score = 31.2 bits (69), Expect = 3.9
Identities = 25/104 (24%), Positives = 47/104 (45%), Gaps = 5/104 (4%)
Frame = +3
Query: 24 RQLNELVSNKDDVGKNIGSLKNAKIQLENDLENCKKTIEELEEE--NATLQMNKERIEMQ 197
++L +++ DD +N K+ + L+ K+ +EE EEE A ++ +R
Sbjct: 1842 KKLKDILLQVDDERRNAEQFKDQADKANMRLKQLKRQLEEAEEEAQRANVRRKLQRELDD 1901
Query: 198 LTATKAQLDRELS---SKDEMHDEQFKILNKKLRDTEATLEEEQ 320
T T ++RE+S SK D F + + +R +E+
Sbjct: 1902 ATETADAMNREVSSLKSKLRRGDLPFVVTRRLVRKGTGECSDEE 1945
>sp|P10587|MYH11_CHICK Myosin-11 (Myosin heavy chain, gizzard smooth muscle)
Length = 1979
Score = 166 bits (419), Expect = 1e-40
Identities = 91/283 (32%), Positives = 159/283 (56%)
Frame = +3
Query: 6 SKSLLNRQLNELVSNKDDVGKNIGSLKNAKIQLENDLENCKKTIEELEEENATLQMNKER 185
+ +L ++ +LVS+KDDVGKN+ L+ +K LE +E K +EELE+E + K R
Sbjct: 1511 TNKMLKAEMEDLVSSKDDVGKNVHELEKSKRTLEQQVEEMKTQLEELEDELQAAEDAKLR 1570
Query: 186 IEMQLTATKAQLDRELSSKDEMHDEQFKILNKKLRDTEATLEEEQKQRTSLASLKKKLEI 365
+E+ + A K+Q +R+L ++DE ++E+ + L K+L + E LE+E+KQR A+ KKKLE+
Sbjct: 1571 LEVNMQAMKSQFERDLQARDEQNEEKRRQLLKQLHEHETELEDERKQRALAAAAKKKLEV 1630
Query: 366 ENVDLMNQXXXXXXXXXXXXRQIKKHQGTSLNSQREMQEVLNAKNEALKQIKELEKRLRA 545
+ DL +Q +Q++K Q + QR++ + A+ E +E EK+ +
Sbjct: 1631 DVKDLESQVDSANKAREEAIKQLRKLQAQMKDYQRDLDDARAAREEIFATARENEKKAKN 1690
Query: 546 AESSTNQLIEDLSQSERIKRTLISERDDALEEIATLTVNKDTAIADKKRIESNLSALNMD 725
E+ QL EDL+ +ER ++ E+++ EE+A+ + + +K+R+E+ ++ L +
Sbjct: 1691 LEAELIQLQEDLAAAERARKQADLEKEEMAEELASANSGRTSLQDEKRRLEARIAQLEEE 1750
Query: 726 YXXXXXXXXXXXDKNKKVTNQLEQVQNELNVERQNATRLENQK 854
D+ +K Q EQ+ NEL ER A + EN +
Sbjct: 1751 LDEEHSNIETMSDRMRKAVQQAEQLNNELATERATAQKNENAR 1793
Score = 70.5 bits (171), Expect = 6e-12
Identities = 58/276 (21%), Positives = 130/276 (47%), Gaps = 1/276 (0%)
Frame = +3
Query: 3 NSKSLLNRQLNELVSNKDDVGKNIGSLKNAKIQLENDLENCKKTIEELEEENATLQMNKE 182
+ K+ L QL+E V K ++ ++I +L IQL + KK ++E T++ K+
Sbjct: 1349 DDKNSLQEQLDEEVEAKQNLERHISTLT---IQLSDS----KKKLQEFTATVETMEEGKK 1401
Query: 183 RIEMQLTATKAQLDRELSSKDEMHDEQFKILNKKLRDTEATLEEEQKQRTSLASLKKKLE 362
+++ ++ + Q + + +S D++ + + L ++L D L+ +++ ++L +KK +
Sbjct: 1402 KLQREIESLTQQFEEKAASYDKLEKTKNR-LQQELDDLVVDLDNQRQLVSNLEKKQKKFD 1460
Query: 363 IENVDLMNQXXXXXXXXXXXXRQIKKHQGTSLNSQREMQEVLNAKNEALKQIKELEKRLR 542
+ N + ++ + +L+ R ++E L AK E + K L+ +
Sbjct: 1461 QMLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEME 1520
Query: 543 AAESSTNQLIEDLSQSERIKRTLISERDDALEEIATLTVNKDTAIADKKRIESNLSALNM 722
SS + + +++ + E+ KRTL + ++ ++ L A K R+E N+ A+
Sbjct: 1521 DLVSSKDDVGKNVHELEKSKRTLEQQVEEMKTQLEELEDELQAAEDAKLRLEVNMQAMKS 1580
Query: 723 DY-XXXXXXXXXXXDKNKKVTNQLEQVQNELNVERQ 827
+ +K +++ QL + + EL ER+
Sbjct: 1581 QFERDLQARDEQNEEKRRQLLKQLHEHETELEDERK 1616
Score = 62.0 bits (149), Expect = 2e-09
Identities = 50/218 (22%), Positives = 98/218 (44%), Gaps = 3/218 (1%)
Frame = +3
Query: 9 KSLLNRQLNELVSNKDDVGKNIGSLKNAKIQLENDLENCKKTIEELEEENATLQMNKERI 188
K + +Q+ +L ++ L+ K+ + ++ + I +E++N L ++ +
Sbjct: 951 KKKMQQQMLDLEEQLEEEEAARQKLQLEKVTADGKIKKMEDDILIMEDQNNKLTKERKLL 1010
Query: 189 EMQLTATKAQLDRELSSKDEMHDEQFKILNKK---LRDTEATLEEEQKQRTSLASLKKKL 359
E +++ L L+ ++E K+ NK + + E L++E+K R L +K+KL
Sbjct: 1011 EERVS----DLTTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKIKRKL 1066
Query: 360 EIENVDLMNQXXXXXXXXXXXXRQIKKHQGTSLNSQREMQEVLNAKNEALKQIKELEKRL 539
E E+ DL Q Q+ K + + +++ + KN ALK+I+EL
Sbjct: 1067 EGESSDLHEQIAELQAQIAELKAQLAKKEEELQAALARLEDETSQKNNALKKIREL---- 1122
Query: 540 RAAESSTNQLIEDLSQSERIKRTLISERDDALEEIATL 653
ES + L EDL + + ++ D EE+ L
Sbjct: 1123 ---ESHISDLQEDLESEKAARNKAEKQKRDLSEELEAL 1157
Score = 55.1 bits (131), Expect = 3e-07
Identities = 69/314 (21%), Positives = 122/314 (38%), Gaps = 35/314 (11%)
Frame = +3
Query: 18 LNRQLNELVSNKDDVGKNIGSLKNAKIQLENDLENCKKTIEELEEENATLQMNKERIEMQ 197
+ RQ E+ + +++ + K + + E +L+ ++ +L EE LQ K + E +
Sbjct: 853 VTRQEEEMQAKDEELQRT----KERQQKAEAELKELEQKHTQLCEEKNLLQ-EKLQAETE 907
Query: 198 LTATKAQLDRELSSKDEMHDEQFKILNKKLRDTEATLEEEQKQRTSLASLKKKLEIENVD 377
L A ++ L++K + L + L + EA +EEE+++ L + KKK++ + +D
Sbjct: 908 LYAEAEEMRVRLAAKKQE-------LEEILHEMEARIEEEEERSQQLQAEKKKMQQQMLD 960
Query: 378 LMNQXXXXXXXXXXXXRQ----------------IKKHQGTSLNSQREMQE--------- 482
L Q + I + Q L +R++ E
Sbjct: 961 LEEQLEEEEAARQKLQLEKVTADGKIKKMEDDILIMEDQNNKLTKERKLLEERVSDLTTN 1020
Query: 483 ----------VLNAKNEALKQIKELEKRLRAAESSTNQLIEDLSQSERIKRTLISERDDA 632
+ KN+ I ELE RL+ E S +L E+IKR L E D
Sbjct: 1021 LAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQEL-------EKIKRKLEGESSDL 1073
Query: 633 LEEIATLTVNKDTAIADKKRIESNLSALNMDYXXXXXXXXXXXDKNKKVTNQLEQVQNEL 812
E+IA L A + E L A K +++ + + +Q +L
Sbjct: 1074 HEQIAELQAQIAELKAQLAKKEEELQAALARLEDETSQKNNALKKIRELESHISDLQEDL 1133
Query: 813 NVERQNATRLENQK 854
E+ + E QK
Sbjct: 1134 ESEKAARNKAEKQK 1147
Score = 54.3 bits (129), Expect = 4e-07
Identities = 53/240 (22%), Positives = 113/240 (47%), Gaps = 6/240 (2%)
Frame = +3
Query: 6 SKSLLNRQLNELVSNKDDVGKNIGSLKNAKIQLENDLENCKKTIEELEE-----ENATLQ 170
+K+ L++ L + D+ I SL AK +E+ + + +++L+ E +
Sbjct: 1224 AKANLDKTKQTLEKDNADLANEIRSLSQAKQDVEHKKKKLEVQLQDLQSKYSDGERVRTE 1283
Query: 171 MNKERIEMQLTATKA-QLDRELSSKDEMHDEQFKILNKKLRDTEATLEEEQKQRTSLASL 347
+N++ ++Q+ L E SK+ + L +L+DT+ L+EE +Q+ ++ +
Sbjct: 1284 LNEKVHKLQIEVENVTSLLNEAESKNIKLTKDVATLGSQLQDTQELLQEETRQKLNVTTK 1343
Query: 348 KKKLEIENVDLMNQXXXXXXXXXXXXRQIKKHQGTSLNSQREMQEVLNAKNEALKQIKEL 527
++LE + L Q R I +S++++QE A E +++ K
Sbjct: 1344 LRQLEDDKNSLQEQLDEEVEAKQNLERHISTLTIQLSDSKKKLQE-FTATVETMEEGK-- 1400
Query: 528 EKRLRAAESSTNQLIEDLSQSERIKRTLISERDDALEEIATLTVNKDTAIADKKRIESNL 707
+K R ES T Q E + +++++T ++ +E+ L V+ D +++++ SNL
Sbjct: 1401 KKLQREIESLTQQFEEKAASYDKLEKT----KNRLQQELDDLVVDLD----NQRQLVSNL 1452
Score = 39.3 bits (90), Expect = 0.014
Identities = 35/171 (20%), Positives = 74/171 (43%), Gaps = 1/171 (0%)
Frame = +3
Query: 33 NELVSNKDDVGKNIGSLKNAKIQLENDLENCKKTIEELEEE-NATLQMNKERIEMQLTAT 209
NEL + + KN +NA+ QLE + + ++E+E + + +E ++ +
Sbjct: 1777 NELATERATAQKN----ENARQQLERQNKELRSKLQEMEGAVKSKFKSTIAALEAKIASL 1832
Query: 210 KAQLDRELSSKDEMHDEQFKILNKKLRDTEATLEEEQKQRTSLASLKKKLEIENVDLMNQ 389
+ QL++E K + + + +KKL+D +E+E+KQ +K + L Q
Sbjct: 1833 EEQLEQEAREK-QAAAKTLRQKDKKLKDALLQVEDERKQAEQYKDQAEKGNLRLKQLKRQ 1891
Query: 390 XXXXXXXXXXXXRQIKKHQGTSLNSQREMQEVLNAKNEALKQIKELEKRLR 542
+ ++ QRE+ E + + +++ L+ +LR
Sbjct: 1892 -------LEEAEEESQRINANRRKLQRELDEATESNDALGREVAALKSKLR 1935
>sp|P35749|MYH11_HUMAN Myosin-11 (Myosin heavy chain, smooth muscle isoform) (SMMHC)
Length = 1972
Score = 165 bits (417), Expect = 2e-40
Identities = 91/283 (32%), Positives = 160/283 (56%)
Frame = +3
Query: 6 SKSLLNRQLNELVSNKDDVGKNIGSLKNAKIQLENDLENCKKTIEELEEENATLQMNKER 185
+ +L ++ +LVS+KDDVGKN+ L+ +K LE +E K +EELE+E + K R
Sbjct: 1505 TNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLR 1564
Query: 186 IEMQLTATKAQLDRELSSKDEMHDEQFKILNKKLRDTEATLEEEQKQRTSLASLKKKLEI 365
+E+ + A K Q +R+L ++DE ++E+ + L ++L + E LE+E+KQR A+ KKKLE
Sbjct: 1565 LEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEG 1624
Query: 366 ENVDLMNQXXXXXXXXXXXXRQIKKHQGTSLNSQREMQEVLNAKNEALKQIKELEKRLRA 545
+ DL Q +Q++K Q + QRE+++ +++E KE EK+ ++
Sbjct: 1625 DLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKS 1684
Query: 546 AESSTNQLIEDLSQSERIKRTLISERDDALEEIATLTVNKDTAIADKKRIESNLSALNMD 725
E+ QL EDL+ +ER ++ E+++ EE+A+ ++ +K+R+E+ ++ L +
Sbjct: 1685 LEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEE 1744
Query: 726 YXXXXXXXXXXXDKNKKVTNQLEQVQNELNVERQNATRLENQK 854
D+ +K T Q EQ+ NEL ER A + E+ +
Sbjct: 1745 LEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESAR 1787
Score = 62.8 bits (151), Expect = 1e-09
Identities = 55/274 (20%), Positives = 117/274 (42%), Gaps = 1/274 (0%)
Frame = +3
Query: 9 KSLLNRQLNELVSNKDDVGKNIGSLKNAKIQLENDLENCKKTIEELEEENATLQMNKERI 188
++ L QL+E + K ++ ++I +L + L++ T+E LEE Q E +
Sbjct: 1345 RNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENL 1404
Query: 189 EMQLTATKAQLDRELSSKDEMHDEQFKILNKKLRDTEATLEEEQKQRTSLASLKKKLEIE 368
Q A D+ +K+ + E L D L+ +++ ++L ++K +
Sbjct: 1405 TQQYEEKAAAYDKLEKTKNRLQQE--------LDDLVVDLDNQRQLVSNLEKKQRKFDQL 1456
Query: 369 NVDLMNQXXXXXXXXXXXXRQIKKHQGTSLNSQREMQEVLNAKNEALKQIKELEKRLRAA 548
+ N + ++ + +L+ R ++E L AK E + K L+ +
Sbjct: 1457 LAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDL 1516
Query: 549 ESSTNQLIEDLSQSERIKRTLISERDDALEEIATLTVNKDTAIADKKRIESNLSALNMDY 728
SS + + +++ + E+ KR L ++ ++ ++ L K R+E N+ AL +
Sbjct: 1517 VSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQF 1576
Query: 729 -XXXXXXXXXXXDKNKKVTNQLEQVQNELNVERQ 827
+K +++ QL + + EL ER+
Sbjct: 1577 ERDLQARDEQNEEKRRQLQRQLHEYETELEDERK 1610
Score = 57.4 bits (137), Expect = 5e-08
Identities = 63/271 (23%), Positives = 116/271 (42%), Gaps = 24/271 (8%)
Frame = +3
Query: 93 KIQLENDLENCKKTIEELEEENATL--QMNKERIEMQLTATK-AQLDRELSSKDEMHDEQ 263
K+QLE K I++LE+E + Q NK E +L + + L L+ ++E
Sbjct: 968 KLQLEKVTAEAK--IKKLEDEILVMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNL 1025
Query: 264 FKILNKK---LRDTEATLEEEQKQRTSLASLKKKLEIENVDLMNQXXXXXXXXXXXXRQI 434
K+ NK + + E L++E+K R L LK+KLE + D Q Q+
Sbjct: 1026 TKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQL 1085
Query: 435 KKHQGTSLNSQREMQEVLNAKNEALKQIKELEKRLRAAESSTNQLIEDLSQSERIKR--- 605
K + + + + + KN ALK+I+ELE + + + +++E+ KR
Sbjct: 1086 AKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSERAARNKAEKQKRDLG 1145
Query: 606 ----TLISERDDALEEIAT-----------LTVNKDTAIADKKRIESNLSALNMDYXXXX 740
L +E +D L+ AT +TV K + + E+ + + +
Sbjct: 1146 EELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAV 1205
Query: 741 XXXXXXXDKNKKVTNQLEQVQNELNVERQNA 833
++ K+ L+ +N+ +E++NA
Sbjct: 1206 EELTEQLEQFKRAKANLD--KNKQTLEKENA 1234
Score = 55.8 bits (133), Expect = 1e-07
Identities = 71/314 (22%), Positives = 123/314 (39%), Gaps = 35/314 (11%)
Frame = +3
Query: 18 LNRQLNELVSNKDDVGKNIGSLKNAKIQLENDLENCKKTIEELEEENATLQMNKERIEMQ 197
+ RQ E+ + +D++ K K + + EN+L+ ++ +L EE LQ + + E +
Sbjct: 847 VTRQEEEMQAKEDELQKT----KERQQKAENELKELEQKHSQLTEEKNLLQ-EQLQAETE 901
Query: 198 LTATKAQLDRELSSKDEMHDEQFKILNKKLRDTEATLEEEQKQRTSLASLKKKLEIENVD 377
L A ++ L++K + L + L + EA LEEE+ + L + +KK+ + +D
Sbjct: 902 LYAEAEEMRVRLAAKKQE-------LEEILHEMEARLEEEEDRGQQLQAERKKMAQQMLD 954
Query: 378 LMNQ-------XXXXXXXXXXXXRQIKK---------HQGTSLNSQREMQE--------- 482
L Q +IKK Q L+ +R++ E
Sbjct: 955 LEEQLEEEEAARQKLQLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDLTTN 1014
Query: 483 ----------VLNAKNEALKQIKELEKRLRAAESSTNQLIEDLSQSERIKRTLISERDDA 632
+ KN+ I ELE RL+ E S +L E++KR L + D
Sbjct: 1015 LAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQEL-------EKLKRKLEGDASDF 1067
Query: 633 LEEIATLTVNKDTAIADKKRIESNLSALNMDYXXXXXXXXXXXDKNKKVTNQLEQVQNEL 812
E+IA L + E L A K +++ + +Q +L
Sbjct: 1068 HEQIADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDL 1127
Query: 813 NVERQNATRLENQK 854
+ ER + E QK
Sbjct: 1128 DSERAARNKAEKQK 1141
Score = 47.4 bits (111), Expect = 5e-05
Identities = 55/251 (21%), Positives = 117/251 (46%), Gaps = 21/251 (8%)
Frame = +3
Query: 18 LNRQLNELVSNKDDVGKNIGSLK--NAKI--------QLENDLENCKKTIEELEEENATL 167
L QL + K ++ KN +L+ NA + Q + ++E+ KK +E +E +
Sbjct: 1208 LTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSK 1267
Query: 168 QMNKERIEMQLTATKAQLDRELSSKDEMHDE----------QFKILNKKLRDTEATLEEE 317
+ ER +L +L E+ S M +E L+ +L+DT+ L+EE
Sbjct: 1268 CSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEE 1327
Query: 318 QKQRTSLASLKKKLEIENVDLMNQXXXXXXXXXXXXRQIKKHQGTSLNSQREMQEVLNAK 497
+Q+ ++++ ++LE E L +Q R I +S++++Q+ +
Sbjct: 1328 TRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFAS-- 1385
Query: 498 NEALKQIKELEKRL-RAAESSTNQLIEDLSQSERIKRTLISERDDALEEIATLTVNKDTA 674
++ ++E +KR + E+ T Q E + +++++T ++ +E+ L V+ D
Sbjct: 1386 --TVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKT----KNRLQQELDDLVVDLD-- 1437
Query: 675 IADKKRIESNL 707
+++++ SNL
Sbjct: 1438 --NQRQLVSNL 1446
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 68,310,790
Number of Sequences: 369166
Number of extensions: 1085127
Number of successful extensions: 8209
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5880
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 7351
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 8534739105
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)