Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_009_G10
(383 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9BUN8|DERL1_HUMAN Derlin-1 (Degradation in endoplasmic ... 136 1e-32
sp|Q99J56|DERL1_MOUSE Derlin-1 (Degradation in endoplasmic ... 136 1e-32
sp|Q71SS4|DERL1_BOVIN Derlin-1 (Degradation in endoplasmic ... 136 1e-32
sp|Q5R9W3|DERL1_PONPY Derlin-1 (Degradation in endoplasmic ... 136 1e-32
sp|Q9VQ57|DERL1_DROME Derlin-1 (DER1-like protein 1) 104 7e-23
sp|Q93561|DERL1_CAEEL Derlin-1 (DER1-like protein 1) (cDerl... 99 4e-21
sp|Q96Q80|DERL3_HUMAN Derlin-3 (Degradation in endoplasmic ... 63 2e-10
sp|Q5RC74|DERL2_PONPY Derlin-2 (Degradation in endoplasmic ... 62 3e-10
sp|Q8BNI4|DERL2_MOUSE Derlin-2 (Degradation in endoplasmic ... 62 4e-10
sp|Q9D8K3|DERL3_MOUSE Derlin-3 (Degradation in endoplasmic ... 62 4e-10
>sp|Q9BUN8|DERL1_HUMAN Derlin-1 (Degradation in endoplasmic reticulum protein 1)
(Der1-like protein 1) (DERtrin-1)
Length = 251
Score = 136 bits (343), Expect = 1e-32
Identities = 62/111 (55%), Positives = 79/111 (71%)
Frame = +1
Query: 1 VIVQFWFGTQFKAMYLPWILLGFNMIISGGGFSDLLGIVVGHLYFFLMFKYPQEFGGNVW 180
+IV FWFGT+FKA YLPW++LGFN II G ++L+G +VGHLYFFLMF+YP + GG +
Sbjct: 140 MIVSFWFGTRFKACYLPWVILGFNYIIGGSVINELIGNLVGHLYFFLMFRYPMDLGGRNF 199
Query: 181 LRTPQFLYKWLPNTVGGVSGFGMAPSSRIARGDTSSNSRPRFPGRGQTLGD 333
L TPQFLY+WLP+ GGVSGFG+ P+S D + G+G LGD
Sbjct: 200 LSTPQFLYRWLPSRRGGVSGFGVPPASMRRAADQNGGGGRHNWGQGFRLGD 250
>sp|Q99J56|DERL1_MOUSE Derlin-1 (Degradation in endoplasmic reticulum protein 1)
(Der1-like protein 1)
Length = 251
Score = 136 bits (343), Expect = 1e-32
Identities = 62/111 (55%), Positives = 79/111 (71%)
Frame = +1
Query: 1 VIVQFWFGTQFKAMYLPWILLGFNMIISGGGFSDLLGIVVGHLYFFLMFKYPQEFGGNVW 180
+IV FWFGT+FKA YLPW++LGFN II G ++L+G +VGHLYFFLMF+YP + GG +
Sbjct: 140 LIVSFWFGTRFKACYLPWVILGFNYIIGGSVINELIGNLVGHLYFFLMFRYPMDLGGRNF 199
Query: 181 LRTPQFLYKWLPNTVGGVSGFGMAPSSRIARGDTSSNSRPRFPGRGQTLGD 333
L TPQFLY+WLP+ GGVSGFG+ P+S D + G+G LGD
Sbjct: 200 LSTPQFLYRWLPSRRGGVSGFGVPPASMRRAADQNGGGGRHNWGQGFRLGD 250
>sp|Q71SS4|DERL1_BOVIN Derlin-1 (Degradation in endoplasmic reticulum protein 1)
(Der1-like protein 1)
Length = 251
Score = 136 bits (343), Expect = 1e-32
Identities = 62/111 (55%), Positives = 79/111 (71%)
Frame = +1
Query: 1 VIVQFWFGTQFKAMYLPWILLGFNMIISGGGFSDLLGIVVGHLYFFLMFKYPQEFGGNVW 180
+IV FWFGT+FKA YLPW++LGFN II G ++L+G +VGHLYFFLMF+YP + GG +
Sbjct: 140 MIVSFWFGTRFKACYLPWVILGFNYIIGGSVINELIGNLVGHLYFFLMFRYPMDLGGRNF 199
Query: 181 LRTPQFLYKWLPNTVGGVSGFGMAPSSRIARGDTSSNSRPRFPGRGQTLGD 333
L TPQFLY+WLP+ GGVSGFG+ P+S D + G+G LGD
Sbjct: 200 LSTPQFLYRWLPSRRGGVSGFGVPPASMRRAADQNGGGGRHNWGQGFRLGD 250
>sp|Q5R9W3|DERL1_PONPY Derlin-1 (Degradation in endoplasmic reticulum protein 1)
(Der1-like protein 1)
Length = 251
Score = 136 bits (343), Expect = 1e-32
Identities = 62/111 (55%), Positives = 79/111 (71%)
Frame = +1
Query: 1 VIVQFWFGTQFKAMYLPWILLGFNMIISGGGFSDLLGIVVGHLYFFLMFKYPQEFGGNVW 180
+IV FWFGT+FKA YLPW++LGFN II G ++L+G +VGHLYFFLMF+YP + GG +
Sbjct: 140 MIVSFWFGTRFKACYLPWVILGFNYIIGGSVINELIGNLVGHLYFFLMFRYPMDLGGRNF 199
Query: 181 LRTPQFLYKWLPNTVGGVSGFGMAPSSRIARGDTSSNSRPRFPGRGQTLGD 333
L TPQFLY+WLP+ GGVSGFG+ P+S D + G+G LGD
Sbjct: 200 LSTPQFLYRWLPSRRGGVSGFGVPPASMRRAADQNGGGGRHNWGQGFRLGD 250
>sp|Q9VQ57|DERL1_DROME Derlin-1 (DER1-like protein 1)
Length = 245
Score = 104 bits (259), Expect = 7e-23
Identities = 52/110 (47%), Positives = 66/110 (60%)
Frame = +1
Query: 1 VIVQFWFGTQFKAMYLPWILLGFNMIISGGGFSDLLGIVVGHLYFFLMFKYPQEFGGNVW 180
V V FWFGT+FKAMYLPW+L F I + L+GI VGH+Y+F F+Y Q+ GG
Sbjct: 139 VTVSFWFGTRFKAMYLPWVLAAFEFIFHFS-LASLVGIFVGHVYYFFKFQYSQDLGGTPL 197
Query: 181 LRTPQFLYKWLPNTVGGVSGFGMAPSSRIARGDTSSNSRPRFPGRGQTLG 330
L TPQFL + +P+ GG GFG+ P SR + + GRG TLG
Sbjct: 198 LETPQFLKRLVPDVSGGFGGFGLPPESRAPPRQATESPW----GRGMTLG 243
>sp|Q93561|DERL1_CAEEL Derlin-1 (DER1-like protein 1) (cDerlin-1)
Length = 245
Score = 98.6 bits (244), Expect = 4e-21
Identities = 41/79 (51%), Positives = 60/79 (75%)
Frame = +1
Query: 4 IVQFWFGTQFKAMYLPWILLGFNMIISGGGFSDLLGIVVGHLYFFLMFKYPQEFGGNVWL 183
IV FWFG +F A YLPW+L GFN ++ GGG ++L+GI+VGH YFF+ KYP E+G ++ +
Sbjct: 140 IVSFWFGMRFPARYLPWVLWGFNAVLRGGGTNELVGILVGHAYFFVALKYPDEYGVDL-I 198
Query: 184 RTPQFLYKWLPNTVGGVSG 240
TP+FL++ +P+ GG+ G
Sbjct: 199 STPEFLHRLIPDEDGGIHG 217
>sp|Q96Q80|DERL3_HUMAN Derlin-3 (Degradation in endoplasmic reticulum protein 3)
(Der1-like protein 3) (DERtrin-3)
Length = 235
Score = 63.2 bits (152), Expect = 2e-10
Identities = 30/67 (44%), Positives = 43/67 (64%)
Frame = +1
Query: 1 VIVQFWFGTQFKAMYLPWILLGFNMIISGGGFSDLLGIVVGHLYFFLMFKYPQEFGGNVW 180
V V F+ F+A +LPW L+GF++++ DLLGI VGH+Y+FL +P + GG
Sbjct: 139 VRVNFFGLLTFQAPFLPWALMGFSLLLGNSILVDLLGIAVGHIYYFLEDVFPNQPGGKRL 198
Query: 181 LRTPQFL 201
L+TP FL
Sbjct: 199 LQTPGFL 205
>sp|Q5RC74|DERL2_PONPY Derlin-2 (Degradation in endoplasmic reticulum protein 2)
(Der1-like protein 2)
sp|Q9GZP9|DERL2_HUMAN Derlin-2 (Degradation in endoplasmic reticulum protein 2)
(Der1-like protein 2) (DERtrin-2) (F-LANa) (F-LAN-1)
Length = 239
Score = 62.4 bits (150), Expect = 3e-10
Identities = 29/67 (43%), Positives = 43/67 (64%)
Frame = +1
Query: 1 VIVQFWFGTQFKAMYLPWILLGFNMIISGGGFSDLLGIVVGHLYFFLMFKYPQEFGGNVW 180
V + F+ F+A +LPW+L+GF++++ DLLGI VGH+YFFL +P + GG
Sbjct: 139 VRMNFFGLLNFQAPFLPWVLMGFSLLLGNSIIVDLLGIAVGHIYFFLEDVFPNQPGGIRI 198
Query: 181 LRTPQFL 201
L+TP L
Sbjct: 199 LKTPSIL 205
>sp|Q8BNI4|DERL2_MOUSE Derlin-2 (Degradation in endoplasmic reticulum protein 2)
(Der1-like protein 2) (F-LANa)
Length = 239
Score = 62.0 bits (149), Expect = 4e-10
Identities = 29/67 (43%), Positives = 43/67 (64%)
Frame = +1
Query: 1 VIVQFWFGTQFKAMYLPWILLGFNMIISGGGFSDLLGIVVGHLYFFLMFKYPQEFGGNVW 180
V + F+ F+A +LPW+L+GF++++ DLLGI VGH+YFFL +P + GG
Sbjct: 139 VRMNFFGLLNFQAPFLPWVLMGFSLLLGNSIIVDLLGIAVGHIYFFLEDIFPNQPGGIRI 198
Query: 181 LRTPQFL 201
L+TP L
Sbjct: 199 LKTPSIL 205
>sp|Q9D8K3|DERL3_MOUSE Derlin-3 (Degradation in endoplasmic reticulum protein 3)
(Der1-like protein 3) (Protein IZP6)
Length = 228
Score = 62.0 bits (149), Expect = 4e-10
Identities = 29/67 (43%), Positives = 43/67 (64%)
Frame = +1
Query: 1 VIVQFWFGTQFKAMYLPWILLGFNMIISGGGFSDLLGIVVGHLYFFLMFKYPQEFGGNVW 180
V V F+ F+A +LPW L+GF++++ +DLLGI+VGH+Y+FL +P + GG
Sbjct: 139 VRVNFFGLLNFQAPFLPWALMGFSLLLGNSVVTDLLGILVGHIYYFLEDVFPNQPGGKRL 198
Query: 181 LRTPQFL 201
L TP L
Sbjct: 199 LLTPSVL 205
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 49,237,494
Number of Sequences: 369166
Number of extensions: 1067097
Number of successful extensions: 2672
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2583
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2668
length of database: 68,354,980
effective HSP length: 94
effective length of database: 50,989,890
effective search space used: 1682666370
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)