Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_009_F19
(535 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q16222|UAP1_HUMAN UDP-N-acetylhexosamine pyrophosphoryla... 197 1e-50
sp|Q91YN5|UAP1_MOUSE UDP-N-acetylhexosamine pyrophosphoryla... 196 4e-50
sp|O64765|UAP1_ARATH Probable UDP-N-acetylglucosamine pyrop... 176 4e-44
sp|O74933|UAP1_CANAL UDP-N-acetylglucosamine pyrophosphorylase 162 6e-40
sp|P43123|UAP1_YEAST UDP-N-acetylglucosamine pyrophosphorylase 159 5e-39
sp|O94617|UAP1_SCHPO Probable UDP-N-acetylglucosamine pyrop... 145 5e-35
sp|Q18493|UAP1_CAEEL Probable UDP-N-acetylglucosamine pyrop... 102 6e-22
sp|P78811|UGPA1_SCHPO Probable UTP--glucose-1-phosphate uri... 37 0.023
sp|P08800|UGPA_DICDI UTP--glucose-1-phosphate uridylyltrans... 37 0.039
sp|O59819|UGPA2_SCHPO Probable UTP--glucose-1-phosphate uri... 36 0.067
>sp|Q16222|UAP1_HUMAN UDP-N-acetylhexosamine pyrophosphorylase (Antigen X) (AGX)
(Sperm-associated antigen 2) [Includes:
UDP-N-acetylgalactosamine pyrophosphorylase (AGX-1);
UDP-N-acetylglucosamine pyrophosphorylase (AGX-2)]
Length = 522
Score = 197 bits (502), Expect = 1e-50
Identities = 98/177 (55%), Positives = 127/177 (71%)
Frame = +2
Query: 5 ISWYIMTSDCTADATMEYFKDNNYFGLSPDQIIFFEQFTLPVVGCNGKIILETKCKISKS 184
I WYIMTS T ++T E+F + YFGL + +IFF+Q LP + +GKIILE K K+S +
Sbjct: 160 IPWYIMTSGRTMESTKEFFTKHKYFGLKKENVIFFQQGMLPAMSFDGKIILEEKNKVSMA 219
Query: 185 PDGNGGLYRALYNYKLVDDMKSRGIKYALVYGVDNILVKIVDPVFLGFCVEKGAECAAKV 364
PDGNGGLYRAL +V+DM+ RGI VY VDNILVK+ DP F+GFC++KGA+C AKV
Sbjct: 220 PDGNGGLYRALAAQNIVEDMEQRGIWSIHVYCVDNILVKVADPRFIGFCIQKGADCGAKV 279
Query: 365 VEKVHPKEAVGIVGKVNVCYQVIEYSEISLETATMRDIKNDKLLYRCGSICTHLFSV 535
VEK +P E VG+V +V+ YQV+EYSEISL TA R + +LL+ G+I H F+V
Sbjct: 280 VEKTNPTEPVGVVCRVDGVYQVVEYSEISLATAQKRS-SDGRLLFNAGNIANHFFTV 335
>sp|Q91YN5|UAP1_MOUSE UDP-N-acetylhexosamine pyrophosphorylase [Includes:
UDP-N-acetylgalactosamine pyrophosphorylase ;
UDP-N-acetylglucosamine pyrophosphorylase ]
Length = 522
Score = 196 bits (497), Expect = 4e-50
Identities = 96/177 (54%), Positives = 127/177 (71%)
Frame = +2
Query: 5 ISWYIMTSDCTADATMEYFKDNNYFGLSPDQIIFFEQFTLPVVGCNGKIILETKCKISKS 184
I WYIMTS T ++T E+F + +FGL + ++FF+Q LP + +GKIILE K K+S +
Sbjct: 160 IPWYIMTSGRTMESTKEFFTKHKFFGLKKENVVFFQQGMLPAMSFDGKIILEEKNKVSMA 219
Query: 185 PDGNGGLYRALYNYKLVDDMKSRGIKYALVYGVDNILVKIVDPVFLGFCVEKGAECAAKV 364
PDGNGGLYRAL +V+DM+ RGI VY VDNILVK+ DP F+GFC++KGA+C AKV
Sbjct: 220 PDGNGGLYRALAAQNIVEDMEQRGICSIHVYCVDNILVKVADPRFIGFCIQKGADCGAKV 279
Query: 365 VEKVHPKEAVGIVGKVNVCYQVIEYSEISLETATMRDIKNDKLLYRCGSICTHLFSV 535
VEK +P E VG+V +V+ YQV+EYSEISL TA R + +LL+ G+I H F+V
Sbjct: 280 VEKTNPTEPVGVVCRVDGVYQVVEYSEISLATAQRRS-SDGRLLFNAGNIANHFFTV 335
>sp|O64765|UAP1_ARATH Probable UDP-N-acetylglucosamine pyrophosphorylase
Length = 502
Score = 176 bits (445), Expect = 4e-44
Identities = 85/180 (47%), Positives = 122/180 (67%), Gaps = 3/180 (1%)
Frame = +2
Query: 5 ISWYIMTSDCTADATMEYFKDNNYFGLSPDQIIFFEQFTLPVVGCNGKIILETKCKISKS 184
I WYIMTS T + T ++FK + YFGL PDQ+ FF+Q TLP + +GK I+ET +SK+
Sbjct: 187 IQWYIMTSPFTHEPTQKFFKSHKYFGLEPDQVTFFQQGTLPCISKDGKFIMETPFSLSKA 246
Query: 185 PDGNGGLYRALYNYKLVDDMKSRGIKYALVYGVDNILVKIVDPVFLGFCVEKGAECAAKV 364
PDGNGG+Y AL + +L++DM SRGIKY YGVDN+LV++ DP FLG+ ++K A AAKV
Sbjct: 247 PDGNGGVYTALKSSRLLEDMASRGIKYVDCYGVDNVLVRVADPTFLGYFIDKSAASAAKV 306
Query: 365 VEKVHPKEAVGIV---GKVNVCYQVIEYSEISLETATMRDIKNDKLLYRCGSICTHLFSV 535
V K +P+E VG+ GK V+EY+E+ A+ + + +L Y ++C H+F++
Sbjct: 307 VRKAYPQEKVGVFVRRGKGGP-LTVVEYTELDQSMASATNQQTGRLQYCWSNVCLHMFTL 365
>sp|O74933|UAP1_CANAL UDP-N-acetylglucosamine pyrophosphorylase
Length = 486
Score = 162 bits (409), Expect = 6e-40
Identities = 89/181 (49%), Positives = 120/181 (66%), Gaps = 4/181 (2%)
Frame = +2
Query: 5 ISWYIMTSDCTADATMEYFKDNNYFGLSPDQIIFFEQFTLPVVGCNG-KIILETKCKISK 181
I+WYIMTS T +AT +F +NNYFGL+ Q+IFF Q TLP G KI+LE+K I +
Sbjct: 163 INWYIMTSGPTRNATESFFIENNYFGLNSHQVIFFNQGTLPCFNLQGNKILLESKNSICQ 222
Query: 182 SPDGNGGLYRALYNYKLVDDMKSRGIKYALVYGVDNILVKIVDPVFLGFCVEKGAECAAK 361
SPDGNGGLY+AL + ++DD+ S+GIK+ +Y VDN LVK+ DP+F+GF + K + A K
Sbjct: 223 SPDGNGGLYKALKDNGILDDLNSKGIKHIHMYCVDNCLVKVADPIFIGFAIAKKFDLATK 282
Query: 362 VVEKVHPKEAVGIV--GKVNVCYQVIEYSEISLETATMRDIK-NDKLLYRCGSICTHLFS 532
VV K E+VG++ + N VIEYSEIS E A +D + + KL R +I H +S
Sbjct: 283 VVRKRDANESVGLIVLDQDNQKPCVIEYSEISQELANKKDPQDSSKLFLRAANIVNHYYS 342
Query: 533 V 535
V
Sbjct: 343 V 343
>sp|P43123|UAP1_YEAST UDP-N-acetylglucosamine pyrophosphorylase
Length = 477
Score = 159 bits (401), Expect = 5e-39
Identities = 87/178 (48%), Positives = 112/178 (62%), Gaps = 1/178 (0%)
Frame = +2
Query: 5 ISWYIMTSDCTADATMEYFKDNNYFGLSPDQIIFFEQFTLPVVGCNGK-IILETKCKISK 181
I WYIMTS T AT YF+++NYFGL+ +QI FF Q TLP GK +++ +S+
Sbjct: 158 IPWYIMTSGPTRAATEAYFQEHNYFGLNKEQITFFNQGTLPAFDLTGKHFLMKDPVNLSQ 217
Query: 182 SPDGNGGLYRALYNYKLVDDMKSRGIKYALVYGVDNILVKIVDPVFLGFCVEKGAECAAK 361
SPDGNGGLYRA+ KL +D RGIK+ +Y VDN+L KI DPVF+GF ++ G E A K
Sbjct: 218 SPDGNGGLYRAIKENKLNEDFDRRGIKHVYMYCVDNVLSKIADPVFIGFAIKHGFELATK 277
Query: 362 VVEKVHPKEAVGIVGKVNVCYQVIEYSEISLETATMRDIKNDKLLYRCGSICTHLFSV 535
V K E+VG++ N VIEYSEIS E A +D K+ L R G+I H + V
Sbjct: 278 AVRKRDAHESVGLIATKNEKPCVIEYSEISNELAEAKD-KDGLLKLRAGNIVNHYYLV 334
>sp|O94617|UAP1_SCHPO Probable UDP-N-acetylglucosamine pyrophosphorylase
Length = 475
Score = 145 bits (367), Expect = 5e-35
Identities = 74/178 (41%), Positives = 109/178 (61%), Gaps = 2/178 (1%)
Frame = +2
Query: 5 ISWYIMTSDCTADATMEYFKDNNYFGLSPDQIIFFEQFTLPVVGCNGKIILETKCKISKS 184
I WYIM S+CT++ T+ +FK+N++FG+ + FF+Q LP + +G+++ E+ ++ +
Sbjct: 158 IPWYIMVSECTSEETISFFKENDFFGIDKKDVFFFQQGVLPCLDISGRVLFESDSSLAWA 217
Query: 185 PDGNGGLYRALYNYKLVDDMKSRGIKYALVYGVDNILVKIVDPVFLGFCVEKGAECAAKV 364
P+GNGG+Y AL + ++DM RGI + Y VDN+LV VDPVF+G K E A K
Sbjct: 218 PNGNGGIYEALLSSGALNDMNRRGILHITAYSVDNVLVLPVDPVFIGMATTKKLEVATKT 277
Query: 365 VEKVHPKEAVGIVGKVNVCYQVIEYSEISLET--ATMRDIKNDKLLYRCGSICTHLFS 532
VEK+ P E VG++ + V+EYSEIS E AT + LL R +I H FS
Sbjct: 278 VEKIDPAEKVGLLVSSHNHPCVVEYSEISDEACKATENVDGHKHLLLRAANIAYHYFS 335
>sp|Q18493|UAP1_CAEEL Probable UDP-N-acetylglucosamine pyrophosphorylase
Length = 484
Score = 102 bits (254), Expect = 6e-22
Identities = 68/179 (37%), Positives = 96/179 (53%), Gaps = 2/179 (1%)
Frame = +2
Query: 5 ISWYIMTSDCTADATMEYFKD-NNYFGLSPD-QIIFFEQFTLPVVGCNGKIILETKCKIS 178
I W +MTS T +AT E+ K + G D QI F Q + G +L TK +
Sbjct: 162 IHWAVMTSPGTEEATREHVKKLAAHHGFDFDEQITIFSQDEIAAYDEQGNFLLGTKGSVV 221
Query: 179 KSPDGNGGLYRALYNYKLVDDMKSRGIKYALVYGVDNILVKIVDPVFLGFCVEKGAECAA 358
+P+GNGGLY A+ + + ++++GIKY VY VDNIL K+ DP F+GF + A+ A
Sbjct: 222 AAPNGNGGLYSAISAH--LPRLRAKGIKYFHVYCVDNILCKVADPHFIGFAISNEADVAT 279
Query: 359 KVVEKVHPKEAVGIVGKVNVCYQVIEYSEISLETATMRDIKNDKLLYRCGSICTHLFSV 535
K V K E VG V +V+EYSE+ E A + + K L+ GSI H F++
Sbjct: 280 KCVPK-QKGELVGSVCLDRGLPRVVEYSELGAELAEQK-TPDGKYLFGAGSIANHFFTM 336
>sp|P78811|UGPA1_SCHPO Probable UTP--glucose-1-phosphate uridylyltransferase (UDP-glucose
pyrophosphorylase) (UDPGP) (UGPase)
Length = 506
Score = 37.4 bits (85), Expect = 0.023
Identities = 21/63 (33%), Positives = 34/63 (53%)
Frame = +2
Query: 185 PDGNGGLYRALYNYKLVDDMKSRGIKYALVYGVDNILVKIVDPVFLGFCVEKGAECAAKV 364
P G+G ++ AL N ++D + ++G +Y V +DN L +VD L VE AE ++
Sbjct: 219 PPGHGDVFEALTNSGIIDTLIAQGKEYLFVSNIDN-LGAVVDLNILNHMVETNAEYLMEL 277
Query: 365 VEK 373
K
Sbjct: 278 TNK 280
>sp|P08800|UGPA_DICDI UTP--glucose-1-phosphate uridylyltransferase (UDP-glucose
pyrophosphorylase) (UDPGP) (UGPase)
Length = 511
Score = 36.6 bits (83), Expect = 0.039
Identities = 29/117 (24%), Positives = 53/117 (45%)
Frame = +2
Query: 185 PDGNGGLYRALYNYKLVDDMKSRGIKYALVYGVDNILVKIVDPVFLGFCVEKGAECAAKV 364
P G+G ++R+L L+D+ + G +Y + V+N L I+D L + E +V
Sbjct: 231 PPGSGDIFRSLQRSGLIDEFLAAGKEYIFISNVEN-LGSIIDLQVLNHIHLQKIEFGLEV 289
Query: 365 VEKVHPKEAVGIVGKVNVCYQVIEYSEISLETATMRDIKNDKLLYRCGSICTHLFSV 535
+++ GI+ ++E S++ E I D L+ +I +L SV
Sbjct: 290 TNRINTDSTGGILMSYKDKLHLLELSQVKPEKL---KIFKDFKLWNTNNIWVNLKSV 343
>sp|O59819|UGPA2_SCHPO Probable UTP--glucose-1-phosphate uridylyltransferase (UDP-glucose
pyrophosphorylase) (UDPGP) (UGPase)
Length = 499
Score = 35.8 bits (81), Expect = 0.067
Identities = 34/157 (21%), Positives = 71/157 (45%), Gaps = 9/157 (5%)
Frame = +2
Query: 5 ISWYIMTSDCTADATMEYFKDNNYFGLSPDQIIFFEQFTLPVVGCNGKIILETKCKISKS 184
+ + +M S T D T + + Y G D I FEQ P ++ ++++ + K+
Sbjct: 152 VPFILMNSYDTNDETCKVLR--KYAGCKID-ISTFEQSRYP------RVFVDSQLPVPKA 202
Query: 185 ---------PDGNGGLYRALYNYKLVDDMKSRGIKYALVYGVDNILVKIVDPVFLGFCVE 337
P G+G ++ AL + ++ + ++G Y V +DN L VD L ++
Sbjct: 203 APSPIEEWYPPGHGDIFDALVHSGTIERLLAQGKDYLFVSNIDN-LGASVDLNILSHVID 261
Query: 338 KGAECAAKVVEKVHPKEAVGIVGKVNVCYQVIEYSEI 448
E + ++ +K VGI+ + +++E +++
Sbjct: 262 NQIEYSMEITDKTKADIKVGILVNQDGLLRLLETNQV 298
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 62,412,517
Number of Sequences: 369166
Number of extensions: 1204637
Number of successful extensions: 2982
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2887
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2976
length of database: 68,354,980
effective HSP length: 103
effective length of database: 49,327,275
effective search space used: 3650218350
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)