Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_009_F07
(587 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q19673|TYR3_CAEEL Putative tyrosinase-like protein tyr-3... 106 5e-23
sp|Q20191|NAS13_CAEEL Zinc metalloproteinase nas-13 precurs... 65 1e-10
sp|P34269|TYR1_CAEEL Putative tyrosinase-like protein tyr-1... 61 2e-09
sp|Q9QXX0|JAG1_MOUSE Jagged-1 precursor (Jagged1) 55 2e-07
sp|P78504|JAG1_HUMAN Jagged-1 precursor (Jagged1) (hJ1) (CD... 55 2e-07
sp|Q63722|JAG1_RAT Jagged-1 precursor (Jagged1) 55 2e-07
sp|P55115|NAS15_CAEEL Zinc metalloproteinase nas-15 precurs... 53 6e-07
sp|Q90Y54|JAG1B_BRARE Jagged-1b precursor (Jagged1b) (Jagged3) 51 2e-06
sp|Q19269|NAS14_CAEEL Zinc metalloproteinase nas-14 precurs... 50 3e-06
sp|Q6DI48|DLLA_BRARE Delta-like protein A precursor (DeltaA... 50 4e-06
>sp|Q19673|TYR3_CAEEL Putative tyrosinase-like protein tyr-3 precursor
Length = 683
Score = 106 bits (264), Expect = 5e-23
Identities = 63/203 (31%), Positives = 89/203 (43%), Gaps = 35/203 (17%)
Frame = +3
Query: 51 CGKENKCADYRKRCPIMAKYGLCESDPSFMLQNCKESCGVCDGSSK-NRPCVDANQDCAG 227
C EN+C C + G C+ +P +M CK SC C + N C D + +CA
Sbjct: 462 CFNENEC------CGPWSAKGECQKNPVYMNVWCKASCRQCTPNYNINEECSDRHTNCAM 515
Query: 228 WAASHECETNPSWMLYNCKKSCNHCRDAR---------LESISNPN-------------- 338
W+ S EC NP WM NC+ SC C +R +SISNP
Sbjct: 516 WSRSGECNKNPLWMSENCRSSCQKCGRSRAATCGGGGGADSISNPTTMPPATNNGQQNTP 575
Query: 339 -----CKDLQIHCLYWANAGECQLNPGWAKQNCPFSCQHC------GGCRDLIQNCQNFA 485
C + C WA G+C+ NPG+ C SC C G C D +C +A
Sbjct: 576 CDSPMCYNEDQCCPIWAQRGQCRSNPGYMTCQCKVSCGVCRPNYVYGPCADYHYDCAAWA 635
Query: 486 NQGYCKTNEVYMNQSCKKTCGFC 554
+G C N+ +M ++C+++C C
Sbjct: 636 RRGECLKNK-WMPENCRRSCNTC 657
Score = 93.6 bits (231), Expect = 3e-19
Identities = 56/192 (29%), Positives = 76/192 (39%), Gaps = 36/192 (18%)
Frame = +3
Query: 6 NPGYMLVSCKKACNVCGKE----NKCADYRKRCPIMAKYGLCESDPSFMLQNCKESCGVC 173
NP YM V CK +C C +C+D C + ++ G C +P +M +NC+ SC C
Sbjct: 481 NPVYMNVWCKASCRQCTPNYNINEECSDRHTNCAMWSRSGECNKNPLWMSENCRSSCQKC 540
Query: 174 ---------------------------DGSSKNRP-----CVDANQDCAGWAASHECETN 257
+ +N P C + +Q C WA +C +N
Sbjct: 541 GRSRAATCGGGGGADSISNPTTMPPATNNGQQNTPCDSPMCYNEDQCCPIWAQRGQCRSN 600
Query: 258 PSWMLYNCKKSCNHCRDARLESISNPNCKDLQIHCLYWANAGECQLNPGWAKQNCPFSCQ 437
P +M CK SC CR + P C D C WA GEC N W +NC SC
Sbjct: 601 PGYMTCQCKVSCGVCRP---NYVYGP-CADYHYDCAAWARRGECLKNK-WMPENCRRSCN 655
Query: 438 HCGGCRDLIQNC 473
C + L C
Sbjct: 656 TCVNQQQLAARC 667
Score = 52.4 bits (124), Expect = 8e-07
Identities = 25/60 (41%), Positives = 31/60 (51%), Gaps = 3/60 (5%)
Frame = +3
Query: 3 SNPGYMLVSCKKACNVCGKE---NKCADYRKRCPIMAKYGLCESDPSFMLQNCKESCGVC 173
SNPGYM CK +C VC CADY C A+ G C + +M +NC+ SC C
Sbjct: 599 SNPGYMTCQCKVSCGVCRPNYVYGPCADYHYDCAAWARRGECLKN-KWMPENCRRSCNTC 657
>sp|Q20191|NAS13_CAEEL Zinc metalloproteinase nas-13 precursor (Nematode astacin 13)
Length = 527
Score = 65.1 bits (157), Expect = 1e-10
Identities = 36/84 (42%), Positives = 41/84 (48%), Gaps = 5/84 (5%)
Frame = +3
Query: 66 KCADYRKRCPIMAKYGLCESDPS--FMLQNCKESCGVCDGSSKNRP-CVDANQDCAGWAA 236
KC D RK C +A+ G CES S FM +NC SCG C K + C DA C WA
Sbjct: 444 KCEDRRKDCEFLARAGHCESRFSIRFMTENCANSCGKCIAEEKRKEVCEDARTWCERWAN 503
Query: 237 SHECETN--PSWMLYNCKKSCNHC 302
S C +M C KSCN C
Sbjct: 504 SGMCNQTVFKDYMRQKCAKSCNFC 527
Score = 49.3 bits (116), Expect = 7e-06
Identities = 27/83 (32%), Positives = 38/83 (45%), Gaps = 11/83 (13%)
Frame = +3
Query: 339 CKDLQIHCLYWANAGECQ--LNPGWAKQNCPFSCQHCGG-------CRDLIQNCQNFANQ 491
C+D + C + A AG C+ + + +NC SC C C D C+ +AN
Sbjct: 445 CEDRRKDCEFLARAGHCESRFSIRFMTENCANSCGKCIAEEKRKEVCEDARTWCERWANS 504
Query: 492 GYCKTN--EVYMNQSCKKTCGFC 554
G C + YM Q C K+C FC
Sbjct: 505 GMCNQTVFKDYMRQKCAKSCNFC 527
Score = 47.8 bits (112), Expect = 2e-05
Identities = 28/86 (32%), Positives = 38/86 (44%), Gaps = 4/86 (4%)
Frame = +3
Query: 198 CVDANQDCAGWAASHECETNPS--WMLYNCKKSCNHCRDARLESISNPNCKDLQIHCLYW 371
C D +DC A + CE+ S +M NC SC C E C+D + C W
Sbjct: 445 CEDRRKDCEFLARAGHCESRFSIRFMTENCANSCGKCI---AEEKRKEVCEDARTWCERW 501
Query: 372 ANAGECQ--LNPGWAKQNCPFSCQHC 443
AN+G C + + +Q C SC C
Sbjct: 502 ANSGMCNQTVFKDYMRQKCAKSCNFC 527
Score = 36.6 bits (83), Expect = 0.048
Identities = 19/59 (32%), Positives = 25/59 (42%), Gaps = 6/59 (10%)
Frame = +3
Query: 15 YMLVSCKKACNVCGKENK----CADYRKRCPIMAKYGLCESD--PSFMLQNCKESCGVC 173
+M +C +C C E K C D R C A G+C +M Q C +SC C
Sbjct: 469 FMTENCANSCGKCIAEEKRKEVCEDARTWCERWANSGMCNQTVFKDYMRQKCAKSCNFC 527
Score = 31.2 bits (69), Expect = 2.0
Identities = 12/39 (30%), Positives = 23/39 (58%), Gaps = 2/39 (5%)
Frame = +3
Query: 444 GGCRDLIQNCQNFANQGYCKT--NEVYMNQSCKKTCGFC 554
G C D ++C+ A G+C++ + +M ++C +CG C
Sbjct: 443 GKCEDRRKDCEFLARAGHCESRFSIRFMTENCANSCGKC 481
>sp|P34269|TYR1_CAEEL Putative tyrosinase-like protein tyr-1 precursor
Length = 601
Score = 60.8 bits (146), Expect = 2e-09
Identities = 30/98 (30%), Positives = 43/98 (43%)
Frame = +3
Query: 198 CVDANQDCAGWAASHECETNPSWMLYNCKKSCNHCRDARLESISNPNCKDLQIHCLYWAN 377
C + + C W+ +EC TN +M C+KSC C+ + +N C D I C YW
Sbjct: 480 CYNEDPCCNQWSRQNECRTNTVYMNRYCRKSCGLCQS----NDNNRGCHDRHISCAYWRG 535
Query: 378 AGECQLNPGWAKQNCPFSCQHCGGCRDLIQNCQNFANQ 491
C W +NC +C C + Q C + A Q
Sbjct: 536 QNFCTRRRQWMAENCQATCGWCN--MNEAQLCASVARQ 571
Score = 60.5 bits (145), Expect = 3e-09
Identities = 23/81 (28%), Positives = 40/81 (49%)
Frame = +3
Query: 60 ENKCADYRKRCPIMAKYGLCESDPSFMLQNCKESCGVCDGSSKNRPCVDANQDCAGWAAS 239
++ C + C ++ C ++ +M + C++SCG+C + NR C D + CA W
Sbjct: 477 QSNCYNEDPCCNQWSRQNECRTNTVYMNRYCRKSCGLCQSNDNNRGCHDRHISCAYWRGQ 536
Query: 240 HECETNPSWMLYNCKKSCNHC 302
+ C WM NC+ +C C
Sbjct: 537 NFCTRRRQWMAENCQATCGWC 557
Score = 50.4 bits (119), Expect = 3e-06
Identities = 23/79 (29%), Positives = 36/79 (45%), Gaps = 6/79 (7%)
Frame = +3
Query: 336 NCKDLQIHCLYWANAGECQLNPGWAKQNCPFSCQHCG------GCRDLIQNCQNFANQGY 497
NC + C W+ EC+ N + + C SC C GC D +C + Q +
Sbjct: 479 NCYNEDPCCNQWSRQNECRTNTVYMNRYCRKSCGLCQSNDNNRGCHDRHISCAYWRGQNF 538
Query: 498 CKTNEVYMNQSCKKTCGFC 554
C +M ++C+ TCG+C
Sbjct: 539 CTRRRQWMAENCQATCGWC 557
Score = 42.4 bits (98), Expect = 9e-04
Identities = 14/29 (48%), Positives = 21/29 (72%)
Frame = +3
Query: 471 CQNFANQGYCKTNEVYMNQSCKKTCGFCR 557
C ++ Q C+TN VYMN+ C+K+CG C+
Sbjct: 487 CNQWSRQNECRTNTVYMNRYCRKSCGLCQ 515
Score = 37.4 bits (85), Expect = 0.028
Identities = 17/61 (27%), Positives = 27/61 (44%), Gaps = 3/61 (4%)
Frame = +3
Query: 3 SNPGYMLVSCKKACNVCGKENK---CADYRKRCPIMAKYGLCESDPSFMLQNCKESCGVC 173
+N YM C+K+C +C + C D C C +M +NC+ +CG C
Sbjct: 498 TNTVYMNRYCRKSCGLCQSNDNNRGCHDRHISCAYWRGQNFCTRRRQWMAENCQATCGWC 557
Query: 174 D 176
+
Sbjct: 558 N 558
>sp|Q9QXX0|JAG1_MOUSE Jagged-1 precursor (Jagged1)
Length = 1218
Score = 54.7 bits (130), Expect = 2e-07
Identities = 49/214 (22%), Positives = 79/214 (36%), Gaps = 30/214 (14%)
Frame = +3
Query: 6 NPGYMLVSCKKACNVCGKENKCADYRKRCPIMAKYGLCESDPSFMLQNCKESCGVCDGSS 185
+PG+ +C + C N + C + C P + + C+ C+
Sbjct: 363 SPGWTGPTCSTNIDDCSPNN--CSHGGTCQDLVNGFKCVCPPQWTGKTCQLDANECEA-- 418
Query: 186 KNRPCVDANQDCAGWAASHECETNPSWMLYNCKKSCNHC-----RDARLESISN------ 332
+PCV+A + C AS+ C+ P WM NC + N C DA + N
Sbjct: 419 --KPCVNA-RSCKNLIASYYCDCLPGWMGQNCDININDCLGQCQNDASCRDLVNGYRCIC 475
Query: 333 ------PNC-KDLQI----------HCLYWANAGECQLNPGWAKQNCPFSCQHC--GGCR 455
+C +D+ HC N +C G++ C +C C+
Sbjct: 476 PPGYAGDHCERDIDECASNPCLNGGHCQNEINRFQCLCPTGFSGNLCQLDIDYCEPNPCQ 535
Query: 456 DLIQNCQNFANQGYCKTNEVYMNQSCKKTCGFCR 557
+ Q C N A+ +CK E Y ++C CR
Sbjct: 536 NGAQ-CYNRASDYFCKCPEDYEGKNCSHLKDHCR 568
Score = 50.1 bits (118), Expect = 4e-06
Identities = 49/196 (25%), Positives = 64/196 (32%), Gaps = 40/196 (20%)
Frame = +3
Query: 30 CKKACNVCGKENKCAD-----------YRKRCPIMAKYGLCE-------SDPSFMLQNCK 155
C K N CG C + Y+ CP CE SDP +CK
Sbjct: 293 CDKDLNYCGTHQPCLNRGTCSNTGPDKYQCSCPEGYSGPNCEIAEHACLSDPCHNRGSCK 352
Query: 156 ESCG----VCDGSSKNRPCVDANQDCAGWAASH-----------ECETNPSWMLYNCKKS 290
E+ C C DC+ SH +C P W C+
Sbjct: 353 ETSSGFECECSPGWTGPTCSTNIDDCSPNNCSHGGTCQDLVNGFKCVCPPQWTGKTCQLD 412
Query: 291 CNHCRDARLESISNPNCKDLQIHCLYWANAGECQLNPGWAKQNCPFS-------CQHCGG 449
N C ++ +CK+L I Y C PGW QNC + CQ+
Sbjct: 413 ANECEAK--PCVNARSCKNL-IASYY------CDCLPGWMGQNCDININDCLGQCQNDAS 463
Query: 450 CRDLIQNCQNFANQGY 497
CRDL+ + GY
Sbjct: 464 CRDLVNGYRCICPPGY 479
Score = 39.7 bits (91), Expect = 0.006
Identities = 40/177 (22%), Positives = 61/177 (34%), Gaps = 14/177 (7%)
Frame = +3
Query: 45 NVCGKENKCADYRKRCPIMAKYGLCESDPSFMLQNCKESCGVCDGSSKNRPCVDANQDCA 224
NVCG KC K+ C+ + F C E+ C+ + PC + C
Sbjct: 597 NVCGPHGKCKSQSG-----GKF-TCDCNKGFTGTYCHENINDCESN----PCKNGGT-CI 645
Query: 225 GWAASHECETNPSWMLYNCKKSCNHCRDARLESISNP-----NCKDLQIHCLYWANAGEC 389
S++C + W +C+ + N C NP C+DL N C
Sbjct: 646 DGVNSYKCICSDGWEGAHCENNINDCS-------QNPCHYGGTCRDL-------VNDFYC 691
Query: 390 QLNPGWAKQNC--------PFSCQHCGGCRDLIQNCQNFANQGYCKTN-EVYMNQSC 533
GW + C +C + G C D + + G+ T + N SC
Sbjct: 692 DCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEVDTFKCMCPGGWEGTTCNIARNSSC 748
Score = 28.9 bits (63), Expect = 9.9
Identities = 25/117 (21%), Positives = 41/117 (35%), Gaps = 9/117 (7%)
Frame = +3
Query: 9 PGYMLVSCKKACNVCGK---------ENKCADYRKRCPIMAKYGLCESDPSFMLQNCKES 161
PGY C++ + C +N+ ++ CP LC+ D + N
Sbjct: 477 PGYAGDHCERDIDECASNPCLNGGHCQNEINRFQCLCPTGFSGNLCQLDIDYCEPN---- 532
Query: 162 CGVCDGSSKNRPCVDANQDCAGWAASHECETNPSWMLYNCKKSCNHCRDARLESISN 332
PC + Q C A+ + C+ + NC +HCR E I +
Sbjct: 533 -----------PCQNGAQ-CYNRASDYFCKCPEDYEGKNCSHLKDHCRTTTCEVIDS 577
>sp|P78504|JAG1_HUMAN Jagged-1 precursor (Jagged1) (hJ1) (CD339 antigen)
Length = 1218
Score = 54.7 bits (130), Expect = 2e-07
Identities = 49/214 (22%), Positives = 79/214 (36%), Gaps = 30/214 (14%)
Frame = +3
Query: 6 NPGYMLVSCKKACNVCGKENKCADYRKRCPIMAKYGLCESDPSFMLQNCKESCGVCDGSS 185
+PG+ +C + C N + C + C P + + C+ C+
Sbjct: 363 SPGWTGPTCSTNIDDCSPNN--CSHGGTCQDLVNGFKCVCPPQWTGKTCQLDANECEA-- 418
Query: 186 KNRPCVDANQDCAGWAASHECETNPSWMLYNCKKSCNHC-----RDARLESISN------ 332
+PCV+A + C AS+ C+ P WM NC + N C DA + N
Sbjct: 419 --KPCVNA-KSCKNLIASYYCDCLPGWMGQNCDININDCLGQCQNDASCRDLVNGYRCIC 475
Query: 333 ------PNC-KDLQI----------HCLYWANAGECQLNPGWAKQNCPFSCQHC--GGCR 455
+C +D+ HC N +C G++ C +C C+
Sbjct: 476 PPGYAGDHCERDIDECASNPCLNGGHCQNEINRFQCLCPTGFSGNLCQLDIDYCEPNPCQ 535
Query: 456 DLIQNCQNFANQGYCKTNEVYMNQSCKKTCGFCR 557
+ Q C N A+ +CK E Y ++C CR
Sbjct: 536 NGAQ-CYNRASDYFCKCPEDYEGKNCSHLKDHCR 568
Score = 50.1 bits (118), Expect = 4e-06
Identities = 51/196 (26%), Positives = 65/196 (33%), Gaps = 40/196 (20%)
Frame = +3
Query: 30 CKKACNVCGKENKCAD-----------YRKRCPIMAKYGLCE-------SDPSFMLQNCK 155
C K N CG C + Y+ CP CE SDP +CK
Sbjct: 293 CDKDLNYCGTHQPCLNGGTCSNTGPDKYQCSCPEGYSGPNCEIAEHACLSDPCHNRGSCK 352
Query: 156 E-SCGV---CDGSSKNRPCVDANQDCAGWAASH-----------ECETNPSWMLYNCKKS 290
E S G C C DC+ SH +C P W C+
Sbjct: 353 ETSLGFECECSPGWTGPTCSTNIDDCSPNNCSHGGTCQDLVNGFKCVCPPQWTGKTCQLD 412
Query: 291 CNHCRDARLESISNPNCKDLQIHCLYWANAGECQLNPGWAKQNCPFS-------CQHCGG 449
N C ++ +CK+L I Y C PGW QNC + CQ+
Sbjct: 413 ANECEAK--PCVNAKSCKNL-IASYY------CDCLPGWMGQNCDININDCLGQCQNDAS 463
Query: 450 CRDLIQNCQNFANQGY 497
CRDL+ + GY
Sbjct: 464 CRDLVNGYRCICPPGY 479
>sp|Q63722|JAG1_RAT Jagged-1 precursor (Jagged1)
Length = 1219
Score = 54.7 bits (130), Expect = 2e-07
Identities = 49/214 (22%), Positives = 79/214 (36%), Gaps = 30/214 (14%)
Frame = +3
Query: 6 NPGYMLVSCKKACNVCGKENKCADYRKRCPIMAKYGLCESDPSFMLQNCKESCGVCDGSS 185
+PG+ +C + C N + C + C P + + C+ C+
Sbjct: 363 SPGWTGPTCSTNIDDCSPNN--CSHGGTCQDLVNGFKCVCPPQWTGKTCQLDANECEA-- 418
Query: 186 KNRPCVDANQDCAGWAASHECETNPSWMLYNCKKSCNHC-----RDARLESISN------ 332
+PCV+A + C AS+ C+ P WM NC + N C DA + N
Sbjct: 419 --KPCVNA-RSCKNLIASYYCDCLPGWMGQNCDININDCLGQCQNDASCRDLVNGYRCIC 475
Query: 333 ------PNC-KDLQI----------HCLYWANAGECQLNPGWAKQNCPFSCQHC--GGCR 455
+C +D+ HC N +C G++ C +C C+
Sbjct: 476 PPGYAGDHCERDIDECASNPCLNGGHCQNEINRFQCLCPTGFSGNLCQLDIDYCEPNPCQ 535
Query: 456 DLIQNCQNFANQGYCKTNEVYMNQSCKKTCGFCR 557
+ Q C N A+ +CK E Y ++C CR
Sbjct: 536 NGAQ-CYNRASDYFCKCPEDYEGKNCSHLKDHCR 568
Score = 50.1 bits (118), Expect = 4e-06
Identities = 49/196 (25%), Positives = 64/196 (32%), Gaps = 40/196 (20%)
Frame = +3
Query: 30 CKKACNVCGKENKCAD-----------YRKRCPIMAKYGLCE-------SDPSFMLQNCK 155
C K N CG C + Y+ CP CE SDP +CK
Sbjct: 293 CDKDLNYCGTHQPCLNRGTCSNTGPDKYQCSCPEGYSGPNCEIAEHACLSDPCHNRGSCK 352
Query: 156 ESCG----VCDGSSKNRPCVDANQDCAGWAASH-----------ECETNPSWMLYNCKKS 290
E+ C C DC+ SH +C P W C+
Sbjct: 353 ETSSGFECECSPGWTGPTCSTNIDDCSPNNCSHGGTCQDLVNGFKCVCPPQWTGKTCQLD 412
Query: 291 CNHCRDARLESISNPNCKDLQIHCLYWANAGECQLNPGWAKQNCPFS-------CQHCGG 449
N C ++ +CK+L I Y C PGW QNC + CQ+
Sbjct: 413 ANECEAK--PCVNARSCKNL-IASYY------CDCLPGWMGQNCDININDCLGQCQNDAS 463
Query: 450 CRDLIQNCQNFANQGY 497
CRDL+ + GY
Sbjct: 464 CRDLVNGYRCICPPGY 479
Score = 42.7 bits (99), Expect = 7e-04
Identities = 41/177 (23%), Positives = 63/177 (35%), Gaps = 14/177 (7%)
Frame = +3
Query: 45 NVCGKENKCADYRKRCPIMAKYGLCESDPSFMLQNCKESCGVCDGSSKNRPCVDANQDCA 224
NVCG KC + K+ C+ + F C E+ C+G+ PC + C
Sbjct: 597 NVCGPHGKC-----KSESGGKF-TCDCNKGFTGTYCHENINDCEGN----PCTNGGT-CI 645
Query: 225 GWAASHECETNPSWMLYNCKKSCNHCRDARLESISNP-----NCKDLQIHCLYWANAGEC 389
S++C + W +C+ + N C NP C+DL N C
Sbjct: 646 DGVNSYKCICSDGWEGAHCENNINDCS-------QNPCHYGGTCRDL-------VNDFYC 691
Query: 390 QLNPGWAKQNC--------PFSCQHCGGCRDLIQNCQNFANQGYCKTN-EVYMNQSC 533
GW + C +C + G C D + + G+ T + N SC
Sbjct: 692 DCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEVDTFKCMCPGGWEGTTCNIARNSSC 748
>sp|P55115|NAS15_CAEEL Zinc metalloproteinase nas-15 precursor (Nematode astacin 15)
Length = 571
Score = 52.8 bits (125), Expect = 6e-07
Identities = 31/118 (26%), Positives = 41/118 (34%), Gaps = 46/118 (38%)
Frame = +3
Query: 339 CKDLQIHCLYWANAGECQLNPGWAKQNCPFSCQHC------------------------- 443
C++L+ C A G C NPGW + NCP SC C
Sbjct: 354 CRNLRGDCDDLAKQGWCIRNPGWMRANCPISCGMCIPTKETQKPYVQTTTQAATTTARPQ 413
Query: 444 ---------------------GGCRDLIQNCQNFANQGYCKTNEVYMNQSCKKTCGFC 554
C DL +C +Q YCK ++ +M C K+CGFC
Sbjct: 414 KPVTQPIQPLPPVPPLPPTTPEDCEDLRVDCLVLVSQRYCKISQNFMKSYCAKSCGFC 471
Score = 51.6 bits (122), Expect = 1e-06
Identities = 35/131 (26%), Positives = 56/131 (42%), Gaps = 2/131 (1%)
Frame = +3
Query: 57 KENKCADYRKRCPIMAKYGLCESDPSFMLQNCKESCGVCDGSSK-NRPCVDANQDCAGWA 233
K ++C + R C +AK G C +P +M NC SCG+C + + +P V A
Sbjct: 350 KPSECRNLRGDCDDLAKQGWCIRNPGWMRANCPISCGMCIPTKETQKPYVQTTTQAATTT 409
Query: 234 A-SHECETNPSWMLYNCKKSCNHCRDARLESISNPNCKDLQIHCLYWANAGECQLNPGWA 410
A + T P L L + +C+DL++ CL + C+++ +
Sbjct: 410 ARPQKPVTQPIQPLPPVPP---------LPPTTPEDCEDLRVDCLVLVSQRYCKISQNFM 460
Query: 411 KQNCPFSCQHC 443
K C SC C
Sbjct: 461 KSYCAKSCGFC 471
Score = 46.2 bits (108), Expect = 6e-05
Identities = 33/135 (24%), Positives = 51/135 (37%), Gaps = 10/135 (7%)
Frame = +3
Query: 69 CADYRKRCPIMAKYGLCESDPSFMLQNCKESCGVC-----DGSSKNRPCVDANQDCAGWA 233
C D R C ++ C+ +FM C +SCG C NRP V +
Sbjct: 437 CEDLRVDCLVLVSQRYCKISQNFMKSYCAKSCGFCFKPPPTEIPDNRPTVVTTRPLVTLP 496
Query: 234 ASHECETNPSWMLYNCKKSCNHCRDARLESISNP----NCKDLQIHCLYWANAGECQ-LN 398
+ +P+ + K+ S C D + C +W +AG C+ +
Sbjct: 497 PAVIRSRSPAPPVSTTTKAAPTTSTTSAAPYSPTPLPSECSDRKHFCSHWKSAGFCEGIF 556
Query: 399 PGWAKQNCPFSCQHC 443
+ K+NCP SC C
Sbjct: 557 MNYMKKNCPASCGLC 571
Score = 30.8 bits (68), Expect = 2.6
Identities = 13/38 (34%), Positives = 21/38 (55%), Gaps = 1/38 (2%)
Frame = +3
Query: 63 NKCADYRKRCPIMAKYGLCESD-PSFMLQNCKESCGVC 173
++C+D + C G CE ++M +NC SCG+C
Sbjct: 534 SECSDRKHFCSHWKSAGFCEGIFMNYMKKNCPASCGLC 571
>sp|Q90Y54|JAG1B_BRARE Jagged-1b precursor (Jagged1b) (Jagged3)
Length = 1213
Score = 50.8 bits (120), Expect = 2e-06
Identities = 46/221 (20%), Positives = 76/221 (34%), Gaps = 39/221 (17%)
Frame = +3
Query: 12 GYMLVSCKKACNVCGKENKCADYRKRCPIMAKYGLCESDPSFMLQNCKESCGVCDGSSKN 191
G+ SC+ + C N+C + C + C P + + C+ C+ +
Sbjct: 362 GWSGTSCEINVDDC-TPNQCK-HGGTCQDLVNGFKCACPPHWTGKTCQIDANECE----D 415
Query: 192 RPCVDANQDCAGWAASHECETNPSWMLYNCKKSCNHCRDARLESISNPNCKDLQIHCLYW 371
+PCV+A + C ++ CE P W NC + N C+ + ++ CKDL
Sbjct: 416 KPCVNA-KSCHNLIGAYFCECLPGWSGQNCDININDCKG---QCLNGGTCKDL------- 464
Query: 372 ANAGECQLNPGWAKQNCPFSCQHC--------GGCRDLIQN------------------- 470
N C PG+ + C C G C+D +
Sbjct: 465 VNGYRCLCPPGYTGEQCEKDVDECASSPCLNGGRCQDEVNGFQCLCPAGFSGQLCQLDID 524
Query: 471 ------------CQNFANQGYCKTNEVYMNQSCKKTCGFCR 557
C N A+ +CK + Y ++C CR
Sbjct: 525 YCKPNPCQNGAQCFNLASDYFCKCPDDYEGKNCSHLKDHCR 565
Score = 47.0 bits (110), Expect = 4e-05
Identities = 45/191 (23%), Positives = 65/191 (34%), Gaps = 10/191 (5%)
Frame = +3
Query: 12 GYMLVSCKKACNVCGKENKCAD----------YRKRCPIMAKYGLCESDPSFMLQNCKES 161
GY V+C++A + C N CA+ Y C I CE + N +
Sbjct: 324 GYSGVNCERAEHAC-LSNPCANGGTCKETSQGYECHCAIGWSGTSCEINVDDCTPNQCKH 382
Query: 162 CGVCDGSSKNRPCVDANQDCAGWAASHECETNPSWMLYNCKKSCNHCRDARLESISNPNC 341
G C QD +C P W C+ N C D ++ +C
Sbjct: 383 GGTC-------------QDLVN---GFKCACPPHWTGKTCQIDANECEDK--PCVNAKSC 424
Query: 342 KDLQIHCLYWANAGECQLNPGWAKQNCPFSCQHCGGCRDLIQNCQNFANQGYCKTNEVYM 521
+L A C+ PGW+ QNC + C G C++ N C Y
Sbjct: 425 HNL-------IGAYFCECLPGWSGQNCDININDCKGQCLNGGTCKDLVNGYRCLCPPGYT 477
Query: 522 NQSCKKTCGFC 554
+ C+K C
Sbjct: 478 GEQCEKDVDEC 488
Score = 31.6 bits (70), Expect = 1.5
Identities = 27/108 (25%), Positives = 40/108 (37%)
Frame = +3
Query: 9 PGYMLVSCKKACNVCGKENKCADYRKRCPIMAKYGLCESDPSFMLQNCKESCGVCDGSSK 188
PGY C+K + C + C + RC C F Q C+ C K
Sbjct: 474 PGYTGEQCEKDVDECAS-SPCLN-GGRCQDEVNGFQCLCPAGFSGQLCQLDIDYC----K 527
Query: 189 NRPCVDANQDCAGWAASHECETNPSWMLYNCKKSCNHCRDARLESISN 332
PC + Q C A+ + C+ + NC +HCR + I +
Sbjct: 528 PNPCQNGAQ-CFNLASDYFCKCPDDYEGKNCSHLKDHCRTTSCQVIDS 574
Score = 31.6 bits (70), Expect = 1.5
Identities = 24/104 (23%), Positives = 39/104 (37%), Gaps = 1/104 (0%)
Frame = +3
Query: 246 CETNPSWMLYNCKKSCNHCRDARLESISNPNCKDLQIHCLYWANAGECQLNPGWAKQNCP 425
CE + C ++ N C SNP C++ C+ N +C GW +C
Sbjct: 612 CECQEGFRGTYCHENINDCE-------SNP-CRNGGT-CIDKVNVYQCICADGWEGVHCE 662
Query: 426 FSCQHCGGCRDLIQN-CQNFANQGYCKTNEVYMNQSCKKTCGFC 554
+ C L + CQ+ N YC+ + ++C C
Sbjct: 663 INIDDCSLNPCLNKGACQDLVNDFYCECRNGWKGKTCHSRDSQC 706
>sp|Q19269|NAS14_CAEEL Zinc metalloproteinase nas-14 precursor (Nematode astacin 14)
Length = 503
Score = 50.4 bits (119), Expect = 3e-06
Identities = 31/129 (24%), Positives = 43/129 (33%), Gaps = 42/129 (32%)
Frame = +3
Query: 183 SKNRPCVDANQDCAGWAASHECETNPSWMLYNCKKSCNHC----------------RDAR 314
S+N+ C D N C W C+ + +M + C+K+CN C R+
Sbjct: 375 SRNKKCEDLNAHCGMWEQLGHCQHSVKYMAHYCRKACNLCEVEVTTTTTTTPKPVPRNKE 434
Query: 315 LE--------------------------SISNPNCKDLQIHCLYWANAGECQLNPGWAKQ 416
E S C+D + C YWA GEC + K
Sbjct: 435 KENKSASSTTRGTSTATSTTPKTTTTTTSAPKEKCEDKNLFCSYWAKIGECNSESKFMKI 494
Query: 417 NCPFSCQHC 443
C SC C
Sbjct: 495 FCKASCGKC 503
Score = 42.0 bits (97), Expect = 0.001
Identities = 25/128 (19%), Positives = 39/128 (30%), Gaps = 46/128 (35%)
Frame = +3
Query: 57 KENKCADYRKRCPIMAKYGLCESDPSFMLQNCKESCGVCD-------------------- 176
+ KC D C + + G C+ +M C+++C +C+
Sbjct: 376 RNKKCEDLNAHCGMWEQLGHCQHSVKYMAHYCRKACNLCEVEVTTTTTTTPKPVPRNKEK 435
Query: 177 --------------------------GSSKNRPCVDANQDCAGWAASHECETNPSWMLYN 278
S+ C D N C+ WA EC + +M
Sbjct: 436 ENKSASSTTRGTSTATSTTPKTTTTTTSAPKEKCEDKNLFCSYWAKIGECNSESKFMKIF 495
Query: 279 CKKSCNHC 302
CK SC C
Sbjct: 496 CKASCGKC 503
Score = 35.0 bits (79), Expect = 0.14
Identities = 14/43 (32%), Positives = 19/43 (44%)
Frame = +3
Query: 315 LESISNPNCKDLQIHCLYWANAGECQLNPGWAKQNCPFSCQHC 443
+E N C+DL HC W G CQ + + C +C C
Sbjct: 372 VERSRNKKCEDLNAHCGMWEQLGHCQHSVKYMAHYCRKACNLC 414
Score = 33.1 bits (74), Expect = 0.53
Identities = 12/35 (34%), Positives = 18/35 (51%)
Frame = +3
Query: 450 CRDLIQNCQNFANQGYCKTNEVYMNQSCKKTCGFC 554
C DL +C + G+C+ + YM C+K C C
Sbjct: 380 CEDLNAHCGMWEQLGHCQHSVKYMAHYCRKACNLC 414
>sp|Q6DI48|DLLA_BRARE Delta-like protein A precursor (DeltaA protein)
Length = 772
Score = 50.1 bits (118), Expect = 4e-06
Identities = 46/192 (23%), Positives = 70/192 (36%), Gaps = 9/192 (4%)
Frame = +3
Query: 9 PGYMLVSCKKACNVCGKENKCADYRKRCPIMAKYGLCESDPSFMLQNCKESCGVC-DGSS 185
PG+ SC+ N C N C + C M C P F +NC+ S C DG
Sbjct: 320 PGFSGASCEIEVNEC-TGNPCRNGGS-CTDMENTYSCTCPPGFYGKNCELSAMTCADG-- 375
Query: 186 KNRPCVDANQDCAGWAASHECETNPSWMLYNCKKSCNHCRDARLESISNPNCKDLQIHCL 365
PC + + + C+ + +NC+K +HC S+ C + C+
Sbjct: 376 ---PCFNGGRCADNPDGGYFCQCPTGYAGFNCEKKIDHC--------SSSPCSN-GARCV 423
Query: 366 YWANAGECQLNPGWAKQNCP--------FSCQHCGGCRDLIQNCQNFANQGYCKTNEVYM 521
N+ CQ G+ NC + CQ+ G CQ A+ C Y
Sbjct: 424 DLVNSYLCQCPDGFTGMNCDRAGDECSMYPCQNGG-------TCQEGASGYMCTCPPGYT 476
Query: 522 NQSCKKTCGFCR 557
++C C+
Sbjct: 477 GRNCSSPVSRCQ 488
Score = 37.0 bits (84), Expect = 0.036
Identities = 28/137 (20%), Positives = 50/137 (36%), Gaps = 2/137 (1%)
Frame = +3
Query: 150 CKESCGVCDGSSKNRPCVDANQDCAGWAASHECETNPSWMLYNCKKSCNHCRDARLESIS 329
C + C + ++PC++ S+ C P + +C+ N C +
Sbjct: 287 CNQDLNYC---THHKPCLNGATCSNTGQGSYTCSCRPGFSGASCEIEVNECTGNPCR--N 341
Query: 330 NPNCKDLQIHCLYWANAGECQLNPGWAKQNCPFSCQHC--GGCRDLIQNCQNFANQGYCK 503
+C D++ N C PG+ +NC S C G C + + N +C+
Sbjct: 342 GGSCTDME-------NTYSCTCPPGFYGKNCELSAMTCADGPCFNGGRCADNPDGGYFCQ 394
Query: 504 TNEVYMNQSCKKTCGFC 554
Y +C+K C
Sbjct: 395 CPTGYAGFNCEKKIDHC 411
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 71,247,897
Number of Sequences: 369166
Number of extensions: 1573834
Number of successful extensions: 5271
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4319
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5020
length of database: 68,354,980
effective HSP length: 105
effective length of database: 48,957,805
effective search space used: 4406202450
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)