Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_009_E02
(837 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9Y4L1|OXRP_HUMAN 150 kDa oxygen-regulated protein precu... 145 1e-34
sp|Q63617|OXRP_RAT 150 kDa oxygen-regulated protein precurs... 145 1e-34
sp|Q60432|OXRP_CRIGR 150 kDa oxygen-regulated protein precu... 145 2e-34
sp|P02827|HSP70_XENLA Heat shock 70 kDa protein (HSP70) 49 2e-05
sp|P11147|HSP7D_DROME Heat shock 70 kDa protein cognate 4 (... 48 3e-05
sp|Q6BZH1|GRP78_DEBHA 78 kDa glucose-regulated protein homo... 48 3e-05
sp|Q707X3|HSP75_ZYGRO Heat shock protein SSB 48 4e-05
sp|P36415|HSP7C_DICDI Heat shock cognate protein (Aginactin) 47 7e-05
sp|Q75E44|HSP75_ASHGO Heat shock protein SSB 47 7e-05
sp|Q24789|HSP70_ECHGR Heat shock cognate 70 kDa protein (HS... 47 9e-05
>sp|Q9Y4L1|OXRP_HUMAN 150 kDa oxygen-regulated protein precursor (Orp150) (Hypoxia
up-regulated 1)
Length = 999
Score = 145 bits (367), Expect = 1e-34
Identities = 86/218 (39%), Positives = 131/218 (60%), Gaps = 4/218 (1%)
Frame = +3
Query: 3 AQIPMPVIKEVILMGGGTRIPKIQEILLKTTEFQELGKSINTDEXXXXXXXXXXXYISPG 182
A++ + I++VIL+GG TR+P++QE+LLK +ELGK+IN DE +S
Sbjct: 370 AEMSLDEIEQVILVGGATRVPRVQEVLLKAVGKEELGKNINADEAAAMGAVYQAAALSKA 429
Query: 183 FKVKTFIVKDANLLPIAVDFLR-FKMTDNKEVAHFTSRILFDAMILFPVKRVITFNKHSK 359
FKVK F+V+DA + PI V+F R + R+LF M +P ++VITFN++S
Sbjct: 430 FKVKPFVVRDAVVYPILVEFTREVEEEPGIHSLKHNKRVLFSRMGPYPQRKVITFNRYSH 489
Query: 360 NFNFNVTIGTQD-IDKKTLFSIEVNNLTEVHSEYMEPSDKYVTDF--KGVKAHFGLDTSG 530
+FNF++ G + + L NLT V + + S K D+ KG+KAHF LD SG
Sbjct: 490 DFNFHINYGDLGFLGPEDLRVFGSQNLTTVKLKGVGDSFKKYPDYESKGIKAHFNLDESG 549
Query: 531 LVTLNYIEALFERQWNNNGKNEASTFEKIGNTISNLFG 644
+++L+ +E++FE ++ + E ST K+GNTIS+LFG
Sbjct: 550 VLSLDRVESVFETLVEDSAEEE-STLTKLGNTISSLFG 586
>sp|Q63617|OXRP_RAT 150 kDa oxygen-regulated protein precursor (Orp150) (Hypoxia
up-regulated 1)
Length = 999
Score = 145 bits (367), Expect = 1e-34
Identities = 87/218 (39%), Positives = 131/218 (60%), Gaps = 4/218 (1%)
Frame = +3
Query: 3 AQIPMPVIKEVILMGGGTRIPKIQEILLKTTEFQELGKSINTDEXXXXXXXXXXXYISPG 182
A++ + I++VIL+GG TR+PK+QE+LLK +ELGK+IN DE +S
Sbjct: 370 AEMSLDQIEQVILVGGPTRVPKVQEVLLKPVGKEELGKNINADEAAAMGAVYQAAALSKA 429
Query: 183 FKVKTFIVKDANLLPIAVDFLR-FKMTDNKEVAHFTSRILFDAMILFPVKRVITFNKHSK 359
FKVK F+V+DA + PI V+F R + R+LF M +P ++VITFN++S
Sbjct: 430 FKVKPFVVRDAVIYPILVEFTREVEEEPGLRSLKHNKRVLFSRMGPYPQRKVITFNRYSH 489
Query: 360 NFNFNVTIGTQD-IDKKTLFSIEVNNLTEVHSEYMEPSDKYVTDF--KGVKAHFGLDTSG 530
+FNF++ G + + L NLT V + + S K D+ KG+KAHF LD SG
Sbjct: 490 DFNFHINYGDLGFLGPEDLRVFGSQNLTTVKLKGVGESFKKYPDYESKGIKAHFNLDESG 549
Query: 531 LVTLNYIEALFERQWNNNGKNEASTFEKIGNTISNLFG 644
+++L+ +E++FE ++ + E ST K+GNTIS+LFG
Sbjct: 550 VLSLDRVESVFETLVEDSPEEE-STLTKLGNTISSLFG 586
>sp|Q60432|OXRP_CRIGR 150 kDa oxygen-regulated protein precursor (Orp150) (Hypoxia
up-regulated 1) (170 kDa glucose regulated protein)
Length = 999
Score = 145 bits (365), Expect = 2e-34
Identities = 87/218 (39%), Positives = 130/218 (59%), Gaps = 4/218 (1%)
Frame = +3
Query: 3 AQIPMPVIKEVILMGGGTRIPKIQEILLKTTEFQELGKSINTDEXXXXXXXXXXXYISPG 182
A++ + I++VIL+GG TR+PK+QE+LLK +ELGK+IN DE +S
Sbjct: 370 AEMSLDEIEQVILVGGATRVPKVQEVLLKAVGKEELGKNINADEAAAMGAVYQAAALSKA 429
Query: 183 FKVKTFIVKDANLLPIAVDFLR-FKMTDNKEVAHFTSRILFDAMILFPVKRVITFNKHSK 359
FKVK F+V+DA + PI V+F R + R+LF M +P +VITFN++S
Sbjct: 430 FKVKPFVVRDAVIYPILVEFTREVEEEPGVRSLKHNKRVLFSRMGPYPQGKVITFNRYSH 489
Query: 360 NFNFNVTIGTQD-IDKKTLFSIEVNNLTEVHSEYMEPSDKYVTDF--KGVKAHFGLDTSG 530
+FNF++ G + + L NLT V + + S K D+ KG+KAHF LD SG
Sbjct: 490 DFNFHINYGDLGFLGPEDLRVFGSQNLTTVKLKGVGESLKKYPDYESKGIKAHFNLDESG 549
Query: 531 LVTLNYIEALFERQWNNNGKNEASTFEKIGNTISNLFG 644
+++L+ +E++FE ++ + E ST K+GNTIS+LFG
Sbjct: 550 VLSLDRVESVFETLVEDSPEEE-STLTKLGNTISSLFG 586
>sp|P02827|HSP70_XENLA Heat shock 70 kDa protein (HSP70)
Length = 647
Score = 48.5 bits (114), Expect = 2e-05
Identities = 49/210 (23%), Positives = 90/210 (42%), Gaps = 5/210 (2%)
Frame = +3
Query: 3 AQIPMPVIKEVILMGGGTRIPKIQEILLKTTEFQELGKSINTDEXXXXXXXXXXXYISPG 182
A++ I E++L+GG TRIPK+Q++L +EL KSIN DE +
Sbjct: 325 AKLDKSQIHEIVLVGGSTRIPKVQKLLQDFFNGRELNKSINPDEAVAYGAAVQAAILMGD 384
Query: 183 FKVKTFIVKDANLLPIAVDFLRFKMTDNKEVAHFTSRILFDAMILFPVKRVITFNKHSKN 362
K+ V+D LL +A ++ E A +L P K+ +F +S N
Sbjct: 385 ---KSENVQDLLLLDVA------PLSLGLETAGGVMTVLIKRNTTIPTKQTQSFTTYSDN 435
Query: 363 FNFNVTIGTQDIDKKTLFSIEVNNLTEVHSEYMEPSDKYVTDFKGVKAHFGLDTSGLVTL 542
+ Q + + + + N L + + P+ + V ++ F +D +G++ +
Sbjct: 436 ---QPGVLIQVFEGERAMTKDNNLLGKFELSGIPPAPRGVPQ---IEVTFDIDANGILNV 489
Query: 543 NYIEALFERQ-----WNNNGKNEASTFEKI 617
+ +E +Q N+ G+ EK+
Sbjct: 490 SAVEKSSGKQNKITITNDKGRLSKEDIEKM 519
>sp|P11147|HSP7D_DROME Heat shock 70 kDa protein cognate 4 (Heat shock 70 kDa protein 88E)
Length = 651
Score = 48.1 bits (113), Expect = 3e-05
Identities = 46/214 (21%), Positives = 88/214 (41%), Gaps = 7/214 (3%)
Frame = +3
Query: 3 AQIPMPVIKEVILMGGGTRIPKIQEILLKTTEFQELGKSINTDEXXXXXXXXXXXYI--S 176
A++ VI +++L+GG TRIPK+Q +L +EL KSIN DE +
Sbjct: 324 AKLDKSVIHDIVLVGGSTRIPKVQRLLQDLFNGKELNKSINPDEAVAYGAAVQAAILHGD 383
Query: 177 PGFKVKTFIVKDANLLPIAVDFLRFKMTDNKEVAHFTSRILFDAMILFPVKRVITFNKHS 356
+V+ ++ D L + + E A +L P K+ TF +S
Sbjct: 384 KSQEVQDLLLLDVTPLSLGI-----------ETAGGVMSVLIKRNTTIPTKQTQTFTTYS 432
Query: 357 KNFNFNVTIGTQDIDKKTLFSIEVNNLTEVHSEYMEPSDKYVTDFKGVKAHFGLDTSGLV 536
N + Q + + + + N L + + P+ + V ++ F +D +G++
Sbjct: 433 DN---QPGVLIQVYEGERAMTKDNNLLGKFELSGIPPAPRGVPQ---IEVTFDIDANGIL 486
Query: 537 TLNYIEALFERQ-----WNNNGKNEASTFEKIGN 623
+ +E ++ N+ G+ E++ N
Sbjct: 487 NVTALERSTNKENKITITNDKGRLSKEDIERMVN 520
>sp|Q6BZH1|GRP78_DEBHA 78 kDa glucose-regulated protein homolog precursor (GRP 78)
(Immunoglobulin heavy chain binding protein homolog)
(BIP)
Length = 683
Score = 48.1 bits (113), Expect = 3e-05
Identities = 43/194 (22%), Positives = 82/194 (42%)
Frame = +3
Query: 24 IKEVILMGGGTRIPKIQEILLKTTEFQELGKSINTDEXXXXXXXXXXXYISPGFKVKTFI 203
+ +++L+GG TRIPK+QE+L K + ++ K IN DE +S V +
Sbjct: 375 VDDIVLVGGSTRIPKVQELLEKFFDGKKASKGINPDEAVAYGAAVQAGVLSGEEGVHDIV 434
Query: 204 VKDANLLPIAVDFLRFKMTDNKEVAHFTSRILFDAMILFPVKRVITFNKHSKNFNFNVTI 383
+ D N L + ++ MT L + P K+ F+ + N T+
Sbjct: 435 LLDVNPLTLGIETTGGVMT-----------TLINRNTAIPTKKSQIFSTAADN---QPTV 480
Query: 384 GTQDIDKKTLFSIEVNNLTEVHSEYMEPSDKYVTDFKGVKAHFGLDTSGLVTLNYIEALF 563
Q + + + + N L + + P+ + V ++ F LD +G++ + ++
Sbjct: 481 LIQVFEGERALAKDNNKLGKFELTSIPPAPRGVPQ---IEVTFSLDANGILKVEAMD--- 534
Query: 564 ERQWNNNGKNEAST 605
GK+E+ T
Sbjct: 535 ----KGTGKSESIT 544
>sp|Q707X3|HSP75_ZYGRO Heat shock protein SSB
Length = 613
Score = 47.8 bits (112), Expect = 4e-05
Identities = 23/44 (52%), Positives = 32/44 (72%)
Frame = +3
Query: 3 AQIPMPVIKEVILMGGGTRIPKIQEILLKTTEFQELGKSINTDE 134
A++P I EV+L+GG TRIPK+Q++L E ++L KSIN DE
Sbjct: 327 AKVPKTEIDEVVLVGGSTRIPKVQKMLSDFFEGKQLEKSINPDE 370
>sp|P36415|HSP7C_DICDI Heat shock cognate protein (Aginactin)
Length = 640
Score = 47.0 bits (110), Expect = 7e-05
Identities = 36/113 (31%), Positives = 51/113 (45%)
Frame = +3
Query: 24 IKEVILMGGGTRIPKIQEILLKTTEFQELGKSINTDEXXXXXXXXXXXYISPGFKVKTFI 203
I E++L+GG TRIPK+Q++L + +EL KSIN DE +S K
Sbjct: 329 IHEIVLVGGSTRIPKVQQLLQEFFNGKELNKSINPDEAVAYGAAVQAAILSNEGGAK--- 385
Query: 204 VKDANLLPIAVDFLRFKMTDNKEVAHFTSRILFDAMILFPVKRVITFNKHSKN 362
V D LL +A ++ E A L P K+ TF+ +S N
Sbjct: 386 VADLLLLDVA------PLSMGLETAGGVMTTLIPRNTTIPCKKTQTFSTYSDN 432
>sp|Q75E44|HSP75_ASHGO Heat shock protein SSB
Length = 613
Score = 47.0 bits (110), Expect = 7e-05
Identities = 24/44 (54%), Positives = 31/44 (70%)
Frame = +3
Query: 3 AQIPMPVIKEVILMGGGTRIPKIQEILLKTTEFQELGKSINTDE 134
AQI I EV+L+GG TRIPK+Q++L E ++L KSIN DE
Sbjct: 327 AQISKSQIDEVVLVGGSTRIPKVQKLLSDFFEGKQLEKSINPDE 370
>sp|Q24789|HSP70_ECHGR Heat shock cognate 70 kDa protein (HSP70)
Length = 665
Score = 46.6 bits (109), Expect = 9e-05
Identities = 35/120 (29%), Positives = 54/120 (45%)
Frame = +3
Query: 3 AQIPMPVIKEVILMGGGTRIPKIQEILLKTTEFQELGKSINTDEXXXXXXXXXXXYISPG 182
A++ + E++L+GG TRIPK+Q++L +EL KSIN DE ++
Sbjct: 326 AKLDKGAVHEIVLVGGSTRIPKVQKLLQDFFNGRELNKSINPDEAVAYGAAVQAAILTGD 385
Query: 183 FKVKTFIVKDANLLPIAVDFLRFKMTDNKEVAHFTSRILFDAMILFPVKRVITFNKHSKN 362
K+ V+D LL +A ++ E A L P K+ TF +S N
Sbjct: 386 ---KSEAVQDLLLLDVA------PLSLGLETAGGVMTALIKRNTTIPTKQTQTFTTYSDN 436
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 81,930,249
Number of Sequences: 369166
Number of extensions: 1499272
Number of successful extensions: 4715
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4563
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4693
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 8148988185
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)