Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_009_C07
(946 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9UI08|EVL_HUMAN Ena/vasodilator-stimulated phosphoprote... 65 2e-10
sp|P70429|EVL_MOUSE Ena/vasodilator-stimulated phosphoprote... 65 2e-10
sp|O08719|EVL_RAT Ena/vasodilator-stimulated phosphoprotein... 62 3e-09
sp|P50552|VASP_HUMAN Vasodilator-stimulated phosphoprotein ... 50 9e-06
sp|P70460|VASP_MOUSE Vasodilator-stimulated phosphoprotein ... 46 1e-04
sp|P50551|VASP_CANFA Vasodilator-stimulated phosphoprotein ... 42 0.002
sp|Q9NJG9|SUZ12_DROME Polycomb protein Su(z)12 (Suppressor ... 39 0.021
sp|O00203|AP3B1_HUMAN Adapter-related protein complex 3 bet... 36 0.14
sp|O77459|KEN_DROME Probable transcription factor Ken (Ken ... 36 0.14
sp|P32583|SRP40_YEAST Suppressor protein SRP40 35 0.31
>sp|Q9UI08|EVL_HUMAN Ena/vasodilator-stimulated phosphoprotein-like protein
(Ena/VASP-like protein)
Length = 416
Score = 65.5 bits (158), Expect = 2e-10
Identities = 60/196 (30%), Positives = 94/196 (47%), Gaps = 16/196 (8%)
Frame = +2
Query: 83 SDEESNQSGLASQLRQAKLKSRGGPVEPDVSSNQNKNVTSSATLGRA----GGDSMMSEM 250
S +ES+ SGLA+ + AKL+ P D S + + TS + RA GG +M EM
Sbjct: 214 SHDESSMSGLAAAIAGAKLRRVQRP--EDASGGSSPSGTSKSDANRASSGGGGGGLMEEM 271
Query: 251 QRVLAARKKA-KEVVKPTGSECTDNGGSGDNSSKNPQWR---QNHHRSQSDCDQTNGTNN 418
++LA R+KA + KP + ++ ++S +P R Q + S++ +N+
Sbjct: 272 NKLLAKRRKAASQSDKPAEKKEDESQMEDPSTSPSPGTRAASQPPNSSEAGRKPWERSNS 331
Query: 419 QSKPAADAAKSTSMQCATLGRKGSLQ--PDSQ-QPVSSITRQ-----DLDNFKREILQEV 574
KP + T + K LQ P S+ +P S+ DLD K+EIL+EV
Sbjct: 332 VEKPVSSILSRTPSVAKSPEAKSPLQSQPHSRMKPAGSVNDMALDAFDLDRMKQEILEEV 391
Query: 575 RSIIQQFKADIIDVIR 622
+ + K +IID IR
Sbjct: 392 VRELHKVKEEIIDAIR 407
>sp|P70429|EVL_MOUSE Ena/vasodilator-stimulated phosphoprotein-like protein
(Ena/VASP-like protein)
Length = 414
Score = 65.5 bits (158), Expect = 2e-10
Identities = 60/194 (30%), Positives = 93/194 (47%), Gaps = 16/194 (8%)
Frame = +2
Query: 89 EESNQSGLASQLRQAKLKSRGGPVEPDVSSNQNKNVTSSATLGRA----GGDSMMSEMQR 256
+ES+ SGLA+ L AKL+ P D S + + TS + RA GG +M EM +
Sbjct: 214 DESSASGLAAALAGAKLRRVQRP--EDASGGSSPSGTSKSDANRASSGGGGGGLMEEMNK 271
Query: 257 VLAARKKA-KEVVKPTGSECTDNGGSGDNSSKNPQWR---QNHHRSQSDCDQTNGTNNQS 424
+LA R+KA + KP + ++ ++S +P R Q + S++ +N+
Sbjct: 272 LLAKRRKAASQTDKPADRKEDESQTEDPSTSPSPGTRATSQPPNSSEAGRKPWERSNSVE 331
Query: 425 KPAADAAKSTSMQCATLGRKGSLQ--PDSQ-QPVSSIT-----RQDLDNFKREILQEVRS 580
KP + T + K LQ P S+ +P S+ DLD K+EIL+EV
Sbjct: 332 KPVSSLLSRTPSVAKSPEAKSPLQSQPHSRVKPAGSVNDVGLDALDLDRMKQEILEEVVR 391
Query: 581 IIQQFKADIIDVIR 622
+ + K +IID IR
Sbjct: 392 ELHKVKEEIIDAIR 405
>sp|O08719|EVL_RAT Ena/vasodilator-stimulated phosphoprotein-like protein
(Ena/VASP-like protein)
Length = 393
Score = 61.6 bits (148), Expect = 3e-09
Identities = 54/183 (29%), Positives = 85/183 (46%), Gaps = 5/183 (2%)
Frame = +2
Query: 89 EESNQSGLASQLRQAKLKSRGGPVEPDVSSNQNKNVTSSATLGRA----GGDSMMSEMQR 256
+ES+ SGLA+ L AKL+ P D S + + TS + RA GG +M EM +
Sbjct: 214 DESSASGLAAALAGAKLRRVQRP--EDASGGSSPSGTSKSDANRASSGGGGGGLMEEMNK 271
Query: 257 VLAARKKA-KEVVKPTGSECTDNGGSGDNSSKNPQWRQNHHRSQSDCDQTNGTNNQSKPA 433
+LA R+KA + KP + +N ++S +P S++ N + KP
Sbjct: 272 LLAKRRKAASQTDKPADRKEDENQTEDPSTSPSPG-------SRATSQPPNSSEAGRKPW 324
Query: 434 ADAAKSTSMQCATLGRKGSLQPDSQQPVSSITRQDLDNFKREILQEVRSIIQQFKADIID 613
+S S++ ++P + DLD K+EIL+EV + + K +IID
Sbjct: 325 E---RSNSVEKPVSSLLSRVKPAGSVNDVGLDALDLDRMKQEILEEVVRELHKVKEEIID 381
Query: 614 VIR 622
IR
Sbjct: 382 AIR 384
>sp|P50552|VASP_HUMAN Vasodilator-stimulated phosphoprotein (VASP)
Length = 380
Score = 50.1 bits (118), Expect = 9e-06
Identities = 44/176 (25%), Positives = 77/176 (43%), Gaps = 7/176 (3%)
Frame = +2
Query: 107 GLASQLRQAKLK-------SRGGPVEPDVSSNQNKNVTSSATLGRAGGDSMMSEMQRVLA 265
GLA+ + AKL+ + GGP P S GR+GG +M EM +LA
Sbjct: 225 GLAAAIAGAKLRKVSKQEEASGGPTAPKAES------------GRSGGGGLMEEMNAMLA 272
Query: 266 ARKKAKEVVKPTGSECTDNGGSGDNSSKNPQWRQNHHRSQSDCDQTNGTNNQSKPAADAA 445
R+KA +V + T + ++ + ++ P ++ R ++ + T + K ++
Sbjct: 273 RRRKATQVGEKTPKD--ESANQEEPEARVPAQSESVRR---PWEKNSTTLPRMKSSSSVT 327
Query: 446 KSTSMQCATLGRKGSLQPDSQQPVSSITRQDLDNFKREILQEVRSIIQQFKADIID 613
S + C SS DL K+E+L+EV+ +Q+ K +II+
Sbjct: 328 TSETQPCTP---------------SSSDYSDLQRVKQELLEEVKKELQKVKEEIIE 368
>sp|P70460|VASP_MOUSE Vasodilator-stimulated phosphoprotein (VASP)
Length = 376
Score = 46.2 bits (108), Expect = 1e-04
Identities = 45/183 (24%), Positives = 74/183 (40%), Gaps = 9/183 (4%)
Frame = +2
Query: 95 SNQSGLASQLRQAKLK-------SRGGPVEPDVSSNQNKNVTSSATLGRAGGDSMMSEMQ 253
S GLA+ + AKL+ + GGP+ P ++ R+ G +M EM
Sbjct: 217 SGAPGLAAAIAGAKLRKVSKQEEASGGPLAPKAENS------------RSTGGGLMEEMN 264
Query: 254 RVLAARKKAKEVVKPTGSECTDNGGSGDNSSKNPQWRQNHHRSQSDCDQTNGTNNQSKPA 433
+LA R+KA +V G+ K+ Q ++ QS+P
Sbjct: 265 AMLARRRKATQV--------------GEKPPKDESASQEESEARLPA--------QSEPV 302
Query: 434 ADAAKSTSMQCATLGRKGSLQPDSQQPVS--SITRQDLDNFKREILQEVRSIIQQFKADI 607
+ S + S+ P + S DL+ K+E+L+EVR +Q+ K +I
Sbjct: 303 RRPWEKNSTTLPRMKSSSSVTTSEAHPSTPCSSDDSDLERVKQELLEEVRKELQKMKEEI 362
Query: 608 IDV 616
I+V
Sbjct: 363 IEV 365
>sp|P50551|VASP_CANFA Vasodilator-stimulated phosphoprotein (VASP)
Length = 384
Score = 42.4 bits (98), Expect = 0.002
Identities = 46/177 (25%), Positives = 75/177 (42%), Gaps = 8/177 (4%)
Frame = +2
Query: 107 GLASQLRQAKLK-------SRGGPVEPDVSSNQNKNVTSSATLGRAGGDSMMSEMQRVLA 265
GLA+ + AKL+ + GGP P S R+ G +M EM +LA
Sbjct: 228 GLAAAIAGAKLRKVSKQEEASGGPPVPKAEST------------RSTGGGLMEEMNAMLA 275
Query: 266 ARKKAKEV-VKPTGSECTDNGGSGDNSSKNPQWRQNHHRSQSDCDQTNGTNNQSKPAADA 442
R+KA +V KP E ++++ P+ R + N+ + P +
Sbjct: 276 RRRKATQVGEKPPKDE---------SANEEPEARVPVPAQSETVRRPWEKNSTTLPRMKS 326
Query: 443 AKSTSMQCATLGRKGSLQPDSQQPVSSITRQDLDNFKREILQEVRSIIQQFKADIID 613
+ S + A P + SS DL+ K+E+L+EVR +Q+ K +II+
Sbjct: 327 SSSVTTSEA--------HPSTP---SSSDESDLERVKQELLEEVRKELQKVKEEIIE 372
>sp|Q9NJG9|SUZ12_DROME Polycomb protein Su(z)12 (Suppressor 12 of zeste protein)
Length = 900
Score = 38.9 bits (89), Expect = 0.021
Identities = 32/139 (23%), Positives = 56/139 (40%), Gaps = 1/139 (0%)
Frame = +2
Query: 74 NNDSDEESNQSGLASQLRQAKLKSRGGPVEPDVSSNQNKNVTSSATLGR-AGGDSMMSEM 250
N + SN +A + L + E Q +NV+ S A + S+
Sbjct: 746 NGSNSSSSNSKNVAKKSADQPLSTLANTRERRSEYGQKRNVSGSRLAATPASKRKLSSKD 805
Query: 251 QRVLAARKKAKEVVKPTGSECTDNGGSGDNSSKNPQWRQNHHRSQSDCDQTNGTNNQSKP 430
VL R++ + TG GGSG +++N + N+H + + + +++ SK
Sbjct: 806 NTVLNKRQRYSDGSPGTGIGNGHGGGSGSGANRN---KSNNHSLPATSNNASSSSSNSKR 862
Query: 431 AADAAKSTSMQCATLGRKG 487
A +STS + G G
Sbjct: 863 AIARRRSTSERTKASGSTG 881
Score = 33.5 bits (75), Expect = 0.90
Identities = 23/77 (29%), Positives = 39/77 (50%), Gaps = 1/77 (1%)
Frame = +2
Query: 125 RQAKLKSRGGPVEPDVSSNQNKNVTSSATLGRAGGDSMMSEMQRVLAARKKAKEVVKP-T 301
+Q K+ P +P ++Q + +S++T G G S M +R+ A K+ P
Sbjct: 678 KQEDPKTLKSPQKPAPPADQ-ASTSSASTSGSGSGSSSMQPPKRMPAHLKRGSAASSPGV 736
Query: 302 GSECTDNGGSGDNSSKN 352
S+ T+NG +G NSS +
Sbjct: 737 QSKGTENGTNGSNSSSS 753
>sp|O00203|AP3B1_HUMAN Adapter-related protein complex 3 beta 1 subunit (Beta3A-adaptin)
(Adaptor protein complex AP-3 beta-1 subunit) (AP-3
complex beta-1 subunit) (Clathrin assembly protein
complex 3 beta-1 large chain)
Length = 1094
Score = 36.2 bits (82), Expect = 0.14
Identities = 33/165 (20%), Positives = 67/165 (40%)
Frame = +2
Query: 56 AKPFQQNNDSDEESNQSGLASQLRQAKLKSRGGPVEPDVSSNQNKNVTSSATLGRAGGDS 235
AK F ++ +E+S+ S S+ G + SN++ + SS+ G
Sbjct: 672 AKKFYSESEEEEDSSDSSSDSESESGSESGEQGESGEEGDSNEDSSEDSSSEQDSESGRE 731
Query: 236 MMSEMQRVLAARKKAKEVVKPTGSECTDNGGSGDNSSKNPQWRQNHHRSQSDCDQTNGTN 415
E +R KAK G +++G + SK ++ S S D ++ +
Sbjct: 732 SGLENKRTAKRNSKAK------GKSDSEDGEKENEKSKTSD--SSNDESSSIEDSSSDSE 783
Query: 416 NQSKPAADAAKSTSMQCATLGRKGSLQPDSQQPVSSITRQDLDNF 550
++S+P ++ + + T ++ + D ++ DLD+F
Sbjct: 784 SESEPESE----SESRRVTKEKEKKTKQDRTPLTKDVSLLDLDDF 824
>sp|O77459|KEN_DROME Probable transcription factor Ken (Ken and Barbie protein)
Length = 601
Score = 36.2 bits (82), Expect = 0.14
Identities = 24/93 (25%), Positives = 41/93 (44%), Gaps = 7/93 (7%)
Frame = +2
Query: 179 NQNKNVTSSATLGRAGGDSMMSEMQRVLAAR-----KKAKEVVKPTGSECTDNGGSGDN- 340
N N N S+A R+GG + E + + K E+V + + + GS N
Sbjct: 180 NSNDNCESAAECERSGGHNNKEEDEDDCTHKDNKSDKDTDEIVNLSNAPPSGTSGSNSNI 239
Query: 341 -SSKNPQWRQNHHRSQSDCDQTNGTNNQSKPAA 436
+S N Q +Q+HH + + N NN + ++
Sbjct: 240 STSSNHQQQQHHHHHHHNHNNNNNNNNNNSSSS 272
>sp|P32583|SRP40_YEAST Suppressor protein SRP40
Length = 406
Score = 35.0 bits (79), Expect = 0.31
Identities = 26/140 (18%), Positives = 65/140 (46%), Gaps = 1/140 (0%)
Frame = +2
Query: 41 STITMAKPFQQNNDSDEESNQSGLASQLRQ-AKLKSRGGPVEPDVSSNQNKNVTSSATLG 217
S+ + + + +++SD +S+ S +S + S + D SS+ + + + S +
Sbjct: 179 SSSSSSSDSESDSESDSQSSSSSSSSDSSSDSDSSSSDSSSDSDSSSSSSSSSSDSDSDS 238
Query: 218 RAGGDSMMSEMQRVLAARKKAKEVVKPTGSECTDNGGSGDNSSKNPQWRQNHHRSQSDCD 397
+ DS S ++ + + + T S+ +D+ D+ S + + +S +
Sbjct: 239 DSSSDSDSSGSSDSSSSSDSSSD--ESTSSDSSDSDSDSDSGSSSELETKEATADESKAE 296
Query: 398 QTNGTNNQSKPAADAAKSTS 457
+T ++N+S P+A ++ S +
Sbjct: 297 ETPASSNESTPSASSSSSAN 316
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 100,457,538
Number of Sequences: 369166
Number of extensions: 1990760
Number of successful extensions: 5879
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5518
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5839
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 9798962520
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)