Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_009_C04
(891 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9VCP0|ELOA1_DROME Probable transcription elongation fac... 43 0.001
sp|Q8NG57|ELOA3_HUMAN RNA polymerase II transcription facto... 41 0.005
sp|Q63187|ELOA1_RAT Transcription elongation factor B polyp... 39 0.019
sp|Q8CB77|ELOA1_MOUSE Transcription elongation factor B pol... 39 0.019
sp|Q14241|ELOA1_HUMAN Transcription elongation factor B pol... 37 0.097
sp|Q96N68|CR015_HUMAN Hypothetical protein C18orf15 34 0.48
sp|Q8IYF1|ELOA2_HUMAN RNA polymerase II transcription facto... 33 0.82
sp|Q9Z1S5|SEPT3_MOUSE Neuronal-specific septin-3 32 2.4
sp|Q6PFR5|TRA2A_MOUSE Transformer-2 protein homolog (TRA-2 ... 32 2.4
sp|Q8NG92|O13H1_HUMAN Olfactory receptor 13H1 31 5.3
>sp|Q9VCP0|ELOA1_DROME Probable transcription elongation factor B polypeptide 3 (RNA
polymerase II transcription factor SIII subunit A)
(Elongin A)
Length = 643
Score = 42.7 bits (99), Expect = 0.001
Identities = 22/98 (22%), Positives = 51/98 (52%)
Frame = +3
Query: 3 VLETEIAQYNYEKLKAFDGDSKKIQRKTECFWEKLFKKNHKSANKRDGETWREAYIRNQS 182
VL + + ++L F+ + + ++ W++ +++ +S + + ETWRE ++R Q
Sbjct: 465 VLRPVLERATPQQLLNFEEYNPYLMDDSDVLWQQHVQRHCRSQRREEMETWREMFLRCQE 524
Query: 183 AQDYRLKEISERLKKNTVESLNAIPKAKLLTNSNLAKP 296
+D +L ++E +K + S + K +L ++ KP
Sbjct: 525 EKDRKLSILAESIKASQKISEAPVRKTQLAFVDSMVKP 562
>sp|Q8NG57|ELOA3_HUMAN RNA polymerase II transcription factor SIII subunit A3 (Elongin A3)
(EloA3) (Transcription elongation factor B polypeptide
3C)
Length = 546
Score = 40.8 bits (94), Expect = 0.005
Identities = 22/97 (22%), Positives = 55/97 (56%)
Frame = +3
Query: 3 VLETEIAQYNYEKLKAFDGDSKKIQRKTECFWEKLFKKNHKSANKRDGETWREAYIRNQS 182
VLE + + ++L + D+ + R+T+ W ++ K ++ E+WRE Y+R +
Sbjct: 362 VLEPVLEGWTPDQLYRTEKDNAALARETDELWRIHCLQDFKEEKPQEHESWRELYLRLRD 421
Query: 183 AQDYRLKEISERLKKNTVESLNAIPKAKLLTNSNLAK 293
A++ RL+ ++ ++ ++ E+ + + K++ +++AK
Sbjct: 422 AREQRLRVVTTKI-RSARENKPSGRQTKMICFNSVAK 457
>sp|Q63187|ELOA1_RAT Transcription elongation factor B polypeptide 3 (RNA polymerase II
transcription factor SIII subunit A) (SIII p110)
(Elongin A) (EloA) (Elongin 110 kDa subunit)
Length = 773
Score = 38.9 bits (89), Expect = 0.019
Identities = 29/102 (28%), Positives = 52/102 (50%), Gaps = 4/102 (3%)
Frame = +3
Query: 3 VLETEIAQYNYEKLKAFDGDSKKIQRKTECFWEKLFKKNHKSANKRDGETWREAYIRNQS 182
VLE + + ++L + + + +T+ W+ ++ K + E+WRE Y+R Q
Sbjct: 575 VLEPVLERCTPDQLYRIEECNHVLIEETDQLWKVHCHRDFKEERPEEYESWREMYLRLQD 634
Query: 183 AQDYRLKEISERLKKNTVESLNA-IPK---AKLLTNSNLAKP 296
A++ RL RL N + S +A PK AK+ +++AKP
Sbjct: 635 AREQRL-----RLLTNNIRSAHANKPKGRQAKMAFVNSVAKP 671
>sp|Q8CB77|ELOA1_MOUSE Transcription elongation factor B polypeptide 3 (RNA polymerase II
transcription factor SIII subunit A) (SIII p110)
(Elongin A) (EloA) (Elongin 110 kDa subunit)
Length = 773
Score = 38.9 bits (89), Expect = 0.019
Identities = 29/102 (28%), Positives = 52/102 (50%), Gaps = 4/102 (3%)
Frame = +3
Query: 3 VLETEIAQYNYEKLKAFDGDSKKIQRKTECFWEKLFKKNHKSANKRDGETWREAYIRNQS 182
VLE + + ++L + + + +T+ W+ ++ K + E+WRE Y+R Q
Sbjct: 575 VLEPVLERCTPDQLYRIEECNHVLIEETDQLWKVHCHRDFKEERPEEYESWREMYLRLQD 634
Query: 183 AQDYRLKEISERLKKNTVESLNA-IPK---AKLLTNSNLAKP 296
A++ RL RL N + S +A PK AK+ +++AKP
Sbjct: 635 AREQRL-----RLLTNNIRSAHANKPKGRQAKMAFVNSVAKP 671
>sp|Q14241|ELOA1_HUMAN Transcription elongation factor B polypeptide 3 (RNA polymerase II
transcription factor SIII subunit A1) (SIII p110)
(Elongin A) (EloA) (Elongin 110 kDa subunit)
Length = 772
Score = 36.6 bits (83), Expect = 0.097
Identities = 22/98 (22%), Positives = 50/98 (51%)
Frame = +3
Query: 3 VLETEIAQYNYEKLKAFDGDSKKIQRKTECFWEKLFKKNHKSANKRDGETWREAYIRNQS 182
VLE + + ++L + + + +T+ W+ ++ K + E+WRE Y+R Q
Sbjct: 576 VLEPVLERCTPDQLYRIEEYNHVLIEETDQLWKVHCHRDFKEERPEEYESWREMYLRLQD 635
Query: 183 AQDYRLKEISERLKKNTVESLNAIPKAKLLTNSNLAKP 296
A++ RL+ +++ ++ +AK+ +++AKP
Sbjct: 636 AREQRLRVLTKNIQFAHANKPKG-RQAKMAFVNSVAKP 672
>sp|Q96N68|CR015_HUMAN Hypothetical protein C18orf15
Length = 181
Score = 34.3 bits (77), Expect = 0.48
Identities = 10/28 (35%), Positives = 16/28 (57%)
Frame = +1
Query: 574 CLCMCARACVCVFVVKCTLIAIIIRFCV 657
C+C+C C CV+V C L+ + C+
Sbjct: 132 CMCVCVHVCACVYVCMCVLVCMCACACM 159
Score = 32.3 bits (72), Expect = 1.8
Identities = 11/27 (40%), Positives = 16/27 (59%)
Frame = +1
Query: 577 LCMCARACVCVFVVKCTLIAIIIRFCV 657
+CMCA CVCV V C + + + C+
Sbjct: 127 VCMCACMCVCVHVCACVYVCMCVLVCM 153
>sp|Q8IYF1|ELOA2_HUMAN RNA polymerase II transcription factor SIII subunit A2 (Elongin A2)
(EloA2) (Transcription elongation factor B polypeptide
3B)
Length = 753
Score = 33.5 bits (75), Expect = 0.82
Identities = 22/97 (22%), Positives = 48/97 (49%)
Frame = +3
Query: 3 VLETEIAQYNYEKLKAFDGDSKKIQRKTECFWEKLFKKNHKSANKRDGETWREAYIRNQS 182
VLE + + ++L D+ + R+T+ ++ K ++ +TWRE Y+R
Sbjct: 554 VLEPVLEGWRPDQLYRRKKDNHALVRETDELRRNHCFQDFKEEKPQENKTWREQYLRLPD 613
Query: 183 AQDYRLKEISERLKKNTVESLNAIPKAKLLTNSNLAK 293
A + RL+ ++ ++ + N +AK++ ++AK
Sbjct: 614 APEQRLRVMTTNIRSARGNNPNG-REAKMICFKSVAK 649
>sp|Q9Z1S5|SEPT3_MOUSE Neuronal-specific septin-3
Length = 465
Score = 32.0 bits (71), Expect = 2.4
Identities = 12/47 (25%), Positives = 22/47 (46%)
Frame = +1
Query: 574 CLCMCARACVCVFVVKCTLIAIIIRFCVANDFQNLCFFSLTFSGTSH 714
C+C+C C+CV C + ++ CV +C + +SG +
Sbjct: 377 CVCVCMYVCMCVMESACVYVCVMESACVC---VCMCVYVCVYSGVRY 420
>sp|Q6PFR5|TRA2A_MOUSE Transformer-2 protein homolog (TRA-2 alpha)
Length = 281
Score = 32.0 bits (71), Expect = 2.4
Identities = 19/75 (25%), Positives = 39/75 (52%)
Frame = -2
Query: 614 TNTHTHARAHIHKQYRIFRFTQMRCNKNTQLYFSRRFSSAFYQRKSQKSSTK*TNLSNGN 435
+ + + +R H H++Y T+ R + + + SR ++ + +R+S+ S +SN
Sbjct: 54 SKSRSRSRRHSHRRY-----TRSRSHSHRRRSRSRSYTPEYRRRRSRSHSP----MSNRR 104
Query: 434 EYTQTAASKPMNTCL 390
+T + A+ NTCL
Sbjct: 105 RHTGSRANPDPNTCL 119
>sp|Q8NG92|O13H1_HUMAN Olfactory receptor 13H1
Length = 308
Score = 30.8 bits (68), Expect = 5.3
Identities = 20/82 (24%), Positives = 36/82 (43%), Gaps = 14/82 (17%)
Frame = +1
Query: 544 LICVKRKIRYCLCMCARACVC---------VFVVKCTLIAIIIRFCVANDFQN-----LC 681
++ + +RY + M CVC + + ++++ + FC AN + L
Sbjct: 123 VVAISNPLRYSVVMNGPVCVCLVATSWGTSLVLTAMLILSLRLHFCGANVINHFACEILS 182
Query: 682 FFSLTFSGTSHHFIMIMILKLF 747
LT S TS + MI+I +F
Sbjct: 183 LIKLTCSDTSLNEFMILITSIF 204
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 85,386,076
Number of Sequences: 369166
Number of extensions: 1604073
Number of successful extensions: 4844
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4477
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4769
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 8934348180
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)