Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= Dr_sW_008_N14 (797 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q13573|SNW1_HUMAN Nuclear protein SkiP (Ski-interacting ... 204 3e-52 sp|Q9CSN1|SNW1_MOUSE Nuclear protein SkiP (Ski-interacting ... 203 5e-52 sp|P39736|BX42_DROME Puff-specific protein Bx42 186 8e-47 sp|Q22836|YGH1_CAEEL Hypothetical protein T27F2.1 in chromo... 154 2e-37 sp|Q09882|PRP45_SCHPO Pre-mRNA splicing factor prp45 (Compl... 143 6e-34 sp|Q759B6|PRP45_ASHGO Pre-mRNA splicing factor PRP45 (Pre-m... 112 1e-24 sp|P54705|SNWA_DICDI Protein snwA 94 3e-19 sp|P28004|PRP45_YEAST Pre-mRNA splicing factor PRP45 (Pre-m... 80 5e-15 sp|Q8SX83|SPEN_DROME Split ends protein 43 0.001 sp|P53278|YG3A_YEAST Hypothetical 92.7 kDa protein in ASN2-... 42 0.001
>sp|Q13573|SNW1_HUMAN Nuclear protein SkiP (Ski-interacting protein) (SNW1 protein) (Nuclear receptor coactivator NCoA-62) Length = 536 Score = 204 bits (518), Expect = 3e-52 Identities = 108/242 (44%), Positives = 159/242 (65%), Gaps = 9/242 (3%) Frame = +1 Query: 1 RPPTKREKAMWKIPPCVSNWKNPRGYTVPLANRVAADGRNNQVTGSNEKINSFSEALFIA 180 R T +E+ WKIPPC+SNWKN +GYT+PL R+AADGR Q NE +EAL+IA Sbjct: 235 RKMTVKEQQEWKIPPCISNWKNAKGYTIPLDKRLAADGRGLQTVHINENFAKLAEALYIA 294 Query: 181 ERKSREEISQRNLLRQKLNQKEKDKNDAKLRQYALKVREKQ---NMATEEDSLEAKERDE 351 +RK+RE + R + +K+ QKEK+K++ KLR+ A K RE++ E++ EA+ERDE Sbjct: 295 DRKAREAVEMRAQVERKMAQKEKEKHEEKLREMAQKARERRAGIKTHVEKEDGEARERDE 354 Query: 352 IRHDRQRIRNRERNMNKAGPEVRRKVL--EDRDISEQIALGQANPLLNRLKDDNVYDRRL 525 IRHDR++ R +RN+++A P+ R K+ E+RDISE IALG NP R ++ YD+RL Sbjct: 355 IRHDRRKERQHDRNLSRAAPDKRSKLQRNENRDISEVIALGVPNP---RTSNEVQYDQRL 411 Query: 526 MDKTGGLDSGFLAGEDEMYNIYDKPL---FNQNKSVYKAPRHTDSSAL-EDIETYQKGKK 693 +++ G+DSGF GEDE+YN+YD+ + +S+Y+ ++ D +D+E K + Sbjct: 412 FNQSKGMDSGFAGGEDEIYNVYDQAWRGGKDMAQSIYRPSKNLDKDMYGDDLEARIKTNR 471 Query: 694 FV 699 FV Sbjct: 472 FV 473
>sp|Q9CSN1|SNW1_MOUSE Nuclear protein SkiP (Ski-interacting protein) (SNW1 protein) Length = 536 Score = 203 bits (516), Expect = 5e-52 Identities = 107/242 (44%), Positives = 159/242 (65%), Gaps = 9/242 (3%) Frame = +1 Query: 1 RPPTKREKAMWKIPPCVSNWKNPRGYTVPLANRVAADGRNNQVTGSNEKINSFSEALFIA 180 R T +E+ WKIPPC+SNWKN +GYT+P+ R+AADGR Q NE +EAL+IA Sbjct: 235 RKMTVKEQQEWKIPPCISNWKNAKGYTIPIDKRLAADGRGLQTVHINENFAKLAEALYIA 294 Query: 181 ERKSREEISQRNLLRQKLNQKEKDKNDAKLRQYALKVREKQ---NMATEEDSLEAKERDE 351 +RK+RE + R + +K+ QKEK+K++ KLR+ A K RE++ E++ EA+ERDE Sbjct: 295 DRKAREAVEMRAQVERKMAQKEKEKHEEKLREMAQKARERRAGIKTHVEKEDGEARERDE 354 Query: 352 IRHDRQRIRNRERNMNKAGPEVRRKVL--EDRDISEQIALGQANPLLNRLKDDNVYDRRL 525 IRHDR++ R +RN+++A P+ R K+ E+RDISE IALG NP R ++ YD+RL Sbjct: 355 IRHDRRKERQHDRNLSRAAPDKRSKLQRNENRDISEVIALGVPNP---RTSNEVQYDQRL 411 Query: 526 MDKTGGLDSGFLAGEDEMYNIYDKPL---FNQNKSVYKAPRHTDSSAL-EDIETYQKGKK 693 +++ G+DSGF GEDE+YN+YD+ + +S+Y+ ++ D +D+E K + Sbjct: 412 FNQSKGMDSGFAGGEDEIYNVYDQAWRGGKDMAQSIYRPSKNLDKDMYGDDLEARIKTNR 471 Query: 694 FV 699 FV Sbjct: 472 FV 473
>sp|P39736|BX42_DROME Puff-specific protein Bx42 Length = 547 Score = 186 bits (471), Expect = 8e-47 Identities = 107/249 (42%), Positives = 153/249 (61%), Gaps = 16/249 (6%) Frame = +1 Query: 1 RPPTKREKAMWKIPPCVSNWKNPRGYTVPLANRVAADGRNNQVTGSNEKINSFSEALFIA 180 R T +E+ WKIPPC+SNWKN +GYT+PL R+AADGR Q NEK +EAL+IA Sbjct: 238 RKVTVKEQKEWKIPPCISNWKNAKGYTIPLDKRLAADGRGLQQVHINEKFAKMAEALYIA 297 Query: 181 ERKSREEISQRNLLRQKLNQKEKDKNDAKLRQYALKVREK----QNMATEEDS------L 330 +RK+RE + R+ L +KL QKEK+K + LR A + RE+ +N E S Sbjct: 298 DRKAREAVEARSQLEKKLAQKEKEKKEDMLRMMAQRAREERAGLRNPEAAEPSGSGATGS 357 Query: 331 EAKERDEIRHDRQRIRNRERNMNKAGPEVRRKVLE--DRDISEQIALGQANPLLNRLKDD 504 E +ER+++R +RQR R R+RN+ +A PE R K+ + +RDISEQIALG P + + Sbjct: 358 EVRERNDLRAERQRERQRDRNLQRAAPEKRSKLQKERERDISEQIALGL--PAKSAGNGE 415 Query: 505 NVYDRRLMDKTGGLDSGFLAGEDEMYNIYDKPLFNQN---KSVYKAPRHTDSSAL-EDIE 672 ++D+RL + T G+DSG+ G+DE YN+YDKP + N +Y+ + DS D++ Sbjct: 416 TLFDQRLFNTTKGMDSGY--GDDEAYNVYDKPWRDSNTLGAHIYRPSKQADSDNYGGDLD 473 Query: 673 TYQKGKKFV 699 K+FV Sbjct: 474 AIVNTKRFV 482
>sp|Q22836|YGH1_CAEEL Hypothetical protein T27F2.1 in chromosome V Length = 535 Score = 154 bits (390), Expect = 2e-37 Identities = 86/203 (42%), Positives = 129/203 (63%), Gaps = 5/203 (2%) Frame = +1 Query: 1 RPPTKREKAMWKIPPCVSNWKNPRGYTVPLANRVAADGRNNQVTGSNEKINSFSEALFIA 180 R T +++ WKIPPC+SNWKNP+G+TV L R+AADGR Q T NE ++AL+IA Sbjct: 238 RKMTAKDQNDWKIPPCISNWKNPKGFTVGLDKRLAADGRGLQQTHINENFAKLADALYIA 297 Query: 181 ERKSREEISQRNLLRQKLNQKEKDKNDAKLRQYALKVREKQN---MATEEDSLEAKERDE 351 +RK+REE+ R L +++ Q +K + +AK+ + A K R++++ +ED + K R+E Sbjct: 298 DRKAREEVETRAQLERRVAQNKKSEQEAKMAEAAAKARQERSAMRRKDDEDDEQVKVREE 357 Query: 352 IRHDRQRIRNRERNMNKAGPEVRRKVLE--DRDISEQIALGQANPLLNRLKDDNVYDRRL 525 IR DR +ERN+ ++ P+ K+ + +RDISE+I LG + R + +D+RL Sbjct: 358 IRRDRLDDIRKERNIARSRPDKADKLRKERERDISEKIVLGLPDTNQKRTGEPQ-FDQRL 416 Query: 526 MDKTGGLDSGFLAGEDEMYNIYD 594 DKT GLDSG A +D+ YN YD Sbjct: 417 FDKTQGLDSG--AMDDDTYNPYD 437
>sp|Q09882|PRP45_SCHPO Pre-mRNA splicing factor prp45 (Complexed with cdc5 protein 13) (Cell cycle control protein cwf13) (Transcriptional coregulator snw1) Length = 557 Score = 143 bits (360), Expect = 6e-34 Identities = 91/267 (34%), Positives = 137/267 (51%), Gaps = 49/267 (18%) Frame = +1 Query: 4 PPTK---REKAMWKIPPCVSNWKNPRGYTVPLANRVAADGRNNQVTGSNEKINSFSEALF 174 PP K +E+ W+IPP +SNWKNP+GYT+PL R+AADGR N+ FSEAL+ Sbjct: 237 PPRKVSAQEQQDWQIPPSISNWKNPKGYTIPLDKRLAADGRGLNDVEINDGFAKFSEALY 296 Query: 175 IAERKSREEISQRNLLRQKLNQKEKDKNDAKLRQYALKVREK---QNMAT---------- 315 ER++REE+ R ++RQK+ +KEK + + +L A K RE +N A+ Sbjct: 297 TVERQAREEVRYRAIMRQKMAEKEKQEKEQRLFMLAQKAREDRMGRNAASSGPSHAKPRS 356 Query: 316 -------------------------EEDSLEAKERDEIRHDRQRIRNRERNMNKAGPEVR 420 +EDS + R E+R +R+R ++ +++ G E R Sbjct: 357 TSVSSEERSRSRAGSFSHHSESENEDEDSEAFRRRQELRRERRRQAEKDLRLSRMGAEKR 416 Query: 421 RKVLE---DRDISEQIALGQANPLLNRLKDDNVYDRRLMDKTGGLDSGFLAGEDEMYNIY 591 K+ E RD++E++ALG + P + D + D RL ++ GL SGF +++ YN+Y Sbjct: 417 AKLAEKDRPRDVAERVALGLSKP---SMSSDTMIDSRLFNQASGLGSGF--QDEDSYNVY 471 Query: 592 DKPLFNQNKSVYKAP-----RHTDSSA 657 DKP S P R D+SA Sbjct: 472 DKPWRAAPSSTLYRPGATLSRQVDASA 498
>sp|Q759B6|PRP45_ASHGO Pre-mRNA splicing factor PRP45 (Pre-mRNA processing protein 45) Length = 443 Score = 112 bits (280), Expect = 1e-24 Identities = 84/247 (34%), Positives = 130/247 (52%), Gaps = 18/247 (7%) Frame = +1 Query: 10 TKREKAMWKIPPCVSNWKNPRGYTVPLANRVAADGRNNQ----VTGSNEKINSFSEALFI 177 TK ++ W+IP VSNWKNP GY + L R+A DGR N+ + NEK+ + AL Sbjct: 172 TKEQREQWRIPSAVSNWKNPNGYAIDLEKRIAIDGRYNREGTAIPAVNEKLLELTNALEE 231 Query: 178 AERKSREEISQRNLLRQKLNQKEKDKNDAKLRQYALKVREKQNMATEEDSLEAKERDEIR 357 AE K+REE+ R R++ +++ + KLR+ A + RE++ + ++ +E DE Sbjct: 232 AESKAREEVRNRAEARKQEAEQQVRLKEDKLRELAQRSREERQRKRRQ-PIDHEEYDESA 290 Query: 358 HDRQRIRNRERN-------MNKAGPEVRRKVL---EDRDISEQIALGQANPLLNRLKDDN 507 RQ RN +R+ ++K R +VL + RD+SE+I LG A P + + D + Sbjct: 291 IIRQTERNEKRDQMKNDMRLSKLSTADRLRVLAHAQGRDVSEKIILGAAKP--SEVPDVH 348 Query: 508 VYDRRLMDKTGGLDSGFLAGEDEMYNIYDKPLFNQN--KSVYKAPRHT--DSSALEDIET 675 YD RL+ K G + G E +YD PLF QN +YK R T ++ AL+ + Sbjct: 349 -YDSRLLTKGAGT---AVPGAPE--QVYDGPLFAQNAMDRLYKPARFTGPENDALDILSK 402 Query: 676 YQKGKKF 696 ++F Sbjct: 403 MTSEQRF 409
>sp|P54705|SNWA_DICDI Protein snwA Length = 685 Score = 94.4 bits (233), Expect = 3e-19 Identities = 47/132 (35%), Positives = 77/132 (58%) Frame = +1 Query: 31 WKIPPCVSNWKNPRGYTVPLANRVAADGRNNQVTGSNEKINSFSEALFIAERKSREEISQ 210 W IPPCVSNWKNP+G+ + + R+ ++G Q N+K F++AL+IAE +REE+S Sbjct: 265 WTIPPCVSNWKNPKGFAISIDKRLVSNGGGLQDVEINDKFAHFTQALYIAESNAREEVSA 324 Query: 211 RNLLRQKLNQKEKDKNDAKLRQYALKVREKQNMATEEDSLEAKERDEIRHDRQRIRNRER 390 R L +KL QKEK++ LR+ A VR +++ ++ K+ + +D + + Sbjct: 325 RAELERKLAQKEKERKQDMLRKLAEDVRNERSGIIQQ-RYTRKDNSDSDNDNDNDSSSDE 383 Query: 391 NMNKAGPEVRRK 426 + NK P + R+ Sbjct: 384 DKNKRTPPMNRR 395
Score = 83.2 bits (204), Expect = 8e-16 Identities = 54/177 (30%), Positives = 98/177 (55%), Gaps = 15/177 (8%) Frame = +1 Query: 184 RKSREEISQRNLLRQKLNQKEKDKNDAKLRQYALKVREKQNMATEEDSLEAK-------- 339 R SR+ R+ + N+ + ++D+ R K R + ++ DS +++ Sbjct: 455 RDSRDNRDSRDSRDNRDNRDNRRRDDSNDRDRYSKRRSDSDSDSDSDSSDSEDERVRRER 514 Query: 340 ----ERDEIRHDRQRIRNRERNMNKAGPEVRRKVLEDRDISEQIALGQANPLLNRLKDDN 507 ERD+IR +++R RE + +G + + +DRDISE+IALGQA+ + +D+ Sbjct: 515 KEKLERDKIRMEKKRELEREYRLEASGKKSKFNRDQDRDISEKIALGQAS---IKRTEDS 571 Query: 508 VYDRRLMDKTGGLDSGFLAGEDEMYNIYDKPLFN--QNKSVYK-APRHTDSSALEDI 669 +YD+RL +++ L SGF G D+ YN+Y KPLF + S+Y+ D+++++D+ Sbjct: 572 IYDQRLFNQSESLTSGF--GNDDSYNVYSKPLFGGAVSNSIYRPKSNQEDNTSIQDV 626
>sp|P28004|PRP45_YEAST Pre-mRNA splicing factor PRP45 (Pre-mRNA processing protein 45) Length = 379 Score = 80.5 bits (197), Expect = 5e-15 Identities = 68/207 (32%), Positives = 98/207 (47%), Gaps = 7/207 (3%) Frame = +1 Query: 31 WKIPPCVSNWKNPRGYTVPLANRV--AADGRNNQVTGSNEKINSFSEALFIAERKSREEI 204 WKIP VSNWKNP GYTV L RV A D NN + N+ SEAL A++K+R+EI Sbjct: 163 WKIPAAVSNWKNPNGYTVALERRVGKALDNENNTI---NDGFMKLSEALENADKKARQEI 219 Query: 205 SQRNLLRQKLNQKEKDKNDAKLRQYALKVREKQNMATEEDSLEAKERDEIRHDRQRIRNR 384 + L++ ++E ++KL++ L R + + T + K + Sbjct: 220 RSKMELKRLAMEQEMLAKESKLKE--LSQRARYHNGTPQTGAIVKPK------------- 264 Query: 385 ERNMNKAGPEVRRKVL---EDRDISEQIALGQANPLLNRLKDDNVYDRRLMDKTGGLDSG 555 + R K L + RD+SE+I LG A + D YD R T G ++ Sbjct: 265 ----KQTSTVARLKELAYSQGRDVSEKIILGAAK---RSEQPDLQYDSRFF--TRGANAS 315 Query: 556 FLAGEDEMYNIYDKPLFNQN--KSVYK 630 ED+ +YD PLF Q +S+YK Sbjct: 316 AKRHEDQ---VYDNPLFVQQDIESIYK 339
>sp|Q8SX83|SPEN_DROME Split ends protein Length = 5560 Score = 42.7 bits (99), Expect = 0.001 Identities = 31/109 (28%), Positives = 55/109 (50%), Gaps = 17/109 (15%) Frame = +1 Query: 181 ERKSREEISQRNLLRQ--------KLNQKEKDKNDAKLRQYALKVREKQNMATEEDSLEA 336 E+K R+E +++L +Q K Q+E++K D K ++ K RE++ A E+ + Sbjct: 1926 EKKERQEKREKDLRKQVEREEKDRKAQQEEREKEDRKAKEEE-KEREREKKAQEDREKKE 1984 Query: 337 KERDEIRHDRQR--------IRNRE-RNMNKAGPEVRRKVLEDRDISEQ 456 +E E+R QR IR ++ R + + R K L D+D+ E+ Sbjct: 1985 REERELREKEQRDKEQKEKEIREKDLREKEQRERDNREKELRDKDLREK 2033
Score = 41.2 bits (95), Expect = 0.003 Identities = 35/115 (30%), Positives = 62/115 (53%), Gaps = 1/115 (0%) Frame = +1 Query: 181 ERKSREEISQRNLLRQKLNQKEKDKNDAKLRQYALKVREKQNMATEEDSLEAKERDEIRH 360 +RK++EE +R R+K Q++++K + + R+ +REK+ E+ E +E+D +R Sbjct: 1960 DRKAKEEEKERE--REKKAQEDREKKEREERE----LREKEQRDKEQKEKEIREKD-LRE 2012 Query: 361 DRQRIR-NRERNMNKAGPEVRRKVLEDRDISEQIALGQANPLLNRLKDDNVYDRR 522 QR R NRE+ E+R K L ++++ E+ Q L+R KD + R Sbjct: 2013 KEQRERDNREK-------ELRDKDLREKEMREK---EQREKELHREKDQREREHR 2057
Score = 37.0 bits (84), Expect = 0.062 Identities = 28/124 (22%), Positives = 55/124 (44%) Frame = +1 Query: 181 ERKSREEISQRNLLRQKLNQKEKDKNDAKLRQYALKVREKQNMATEEDSLEAKERDEIRH 360 E+K REE R ++ QKEK+ + LR+ + R+ + + L KE E + Sbjct: 1981 EKKEREERELREKEQRDKEQKEKEIREKDLREKEQRERDNREKELRDKDLREKEMRE-KE 2039 Query: 361 DRQRIRNRERNMNKAGPEVRRKVLEDRDISEQIALGQANPLLNRLKDDNVYDRRLMDKTG 540 R++ +RE++ + + + D+ ++ G R+++ + Y + MD G Sbjct: 2040 QREKELHREKDQREREHREKEQSRRAMDVEQEGRGG-------RMRELSSYQKSKMDIAG 2092 Query: 541 GLDS 552 S Sbjct: 2093 EASS 2096
Score = 33.1 bits (74), Expect = 0.90 Identities = 24/121 (19%), Positives = 58/121 (47%) Frame = +1 Query: 94 NRVAADGRNNQVTGSNEKINSFSEALFIAERKSREEISQRNLLRQKLNQKEKDKNDAKLR 273 N ++D R N T + K + +E + +++N +K ++ ++K + LR Sbjct: 1880 NASSSDKRKNSSTSQSSKSATPRIEDDSSEADDTADKAEKNQRHEKEKKERQEKREKDLR 1939 Query: 274 QYALKVREKQNMATEEDSLEAKERDEIRHDRQRIRNRERNMNKAGPEVRRKVLEDRDISE 453 + RE+++ +++ E ++R +++R R + KA + +K E+R++ E Sbjct: 1940 KQV--EREEKDRKAQQEEREKEDRKAKEEEKEREREK-----KAQEDREKKEREERELRE 1992 Query: 454 Q 456 + Sbjct: 1993 K 1993
>sp|P53278|YG3A_YEAST Hypothetical 92.7 kDa protein in ASN2-PHB1 intergenic region Length = 816 Score = 42.4 bits (98), Expect = 0.001 Identities = 44/170 (25%), Positives = 85/170 (50%), Gaps = 8/170 (4%) Frame = +1 Query: 7 PTKREK----AMWKIPPCVSNWKNPRGYTVPLANRVAADGRNNQVTGSNEKINSFSEALF 174 P+++E+ A+WK P S K+ T +N VA N ++ ++ S+A++ Sbjct: 367 PSRKERTGIFALWKSPTSSSTQKSK---TAAPSNPVATP-ENPELIVKTKEHGYLSKAVY 422 Query: 175 IAERKSREEISQRNLLRQKLNQKEKDKNDAKLRQYALKVREKQNMATE-EDSLEA---KE 342 + E+I Q L L KEKDK DAK ++Y K+++ QN E E+S++A + Sbjct: 423 -DKINYDEKIHQAWLA--DLRAKEKDKYDAKNKEYKEKLQDLQNQIDEIENSMKAMREET 479 Query: 343 RDEIRHDRQRIRNRERNMNKAGPEVRRKVLEDRDISEQIALGQANPLLNR 492 ++I + R+ + ++N + +L+D + + L + N +L++ Sbjct: 480 SEKIEVSKNRLVKKIIDVNAEHNNKKLMILKDTENMKNQKLQEKNEVLDK 529
Score = 33.5 bits (75), Expect = 0.69 Identities = 25/95 (26%), Positives = 46/95 (48%), Gaps = 11/95 (11%) Frame = +1 Query: 181 ERKSREEISQRNLLRQKLNQKEKDKNDAKL--RQYALKVREKQN---------MATEEDS 327 ERK +EE NLL ++ + E+ + A+L Q +V++ N +ATEE Sbjct: 678 ERKRKEE----NLLEKQRQELEEQAHQAQLDHEQQITQVKQTYNDQLTELQDKLATEEKE 733 Query: 328 LEAKERDEIRHDRQRIRNRERNMNKAGPEVRRKVL 432 LEA +R+ R ++ + A +++++L Sbjct: 734 LEAVKRERTRLQAEKAIEEQTRQKNADEALKQEIL 768
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 79,284,040 Number of Sequences: 369166 Number of extensions: 1485591 Number of successful extensions: 6537 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 5579 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 6214 length of database: 68,354,980 effective HSP length: 109 effective length of database: 48,218,865 effective search space used: 7522142940 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)