Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_008_M03
(932 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q91YI4|ARRB2_MOUSE Beta-arrestin-2 (Arrestin, beta 2) 45 4e-04
sp|P29066|ARRB1_RAT Beta-arrestin-1 (Arrestin, beta 1) 45 4e-04
sp|P29067|ARRB2_RAT Beta-arrestin-2 (Arrestin, beta 2) 45 4e-04
sp|P49407|ARRB1_HUMAN Beta-arrestin-1 (Arrestin, beta 1) 45 4e-04
sp|P17870|ARRB1_BOVIN Beta-arrestin-1 (Arrestin, beta 1) 45 4e-04
sp|Q8BWG8|ARRB1_MOUSE Beta-arrestin-1 (Arrestin, beta 1) 43 0.001
sp|P32121|ARRB2_HUMAN Beta-arrestin-2 (Arrestin, beta 2) 42 0.002
sp|P32120|ARRB2_BOVIN Beta-arrestin-2 (Arrestin, beta 2) (A... 42 0.002
sp|P55274|ARRH_HELVI ARRESTIN HOMOLOG 40 0.007
sp|P15372|ARRA_DROME Phosrestin-2 (Phosrestin II) (Arrestin... 40 0.009
>sp|Q91YI4|ARRB2_MOUSE Beta-arrestin-2 (Arrestin, beta 2)
Length = 410
Score = 44.7 bits (104), Expect = 4e-04
Identities = 34/134 (25%), Positives = 60/134 (44%), Gaps = 1/134 (0%)
Frame = +1
Query: 451 GLHVFNFEFQLPAHLPASFVVPDVPEADCFHAFVIYNIKIEVVNVTHQVSHSRERDILVF 630
G H F F +P +LP S + PE V + I+ + SH R L+
Sbjct: 110 GQHAHPFFFTIPQNLPCSVTLQPGPEDTGKACGVDFEIRAFCAKSIEEKSHKRNSVRLII 169
Query: 631 KSLDLT-QFPKLKDKITLRKEFQISECCASKSKLLCELTVNKCAFVPGEILSVEVLVKNG 807
+ + + P + + F +S+ + L E +++K + GE L+V V V N
Sbjct: 170 RKVQFAPETPGPQPSAETTRHFLMSD----RRSLHLEASLDKELYYHGEPLNVNVHVTNN 225
Query: 808 SAKPIESVQLSLYQ 849
SAK ++ +++S+ Q
Sbjct: 226 SAKTVKKIRVSVRQ 239
>sp|P29066|ARRB1_RAT Beta-arrestin-1 (Arrestin, beta 1)
Length = 418
Score = 44.7 bits (104), Expect = 4e-04
Identities = 38/151 (25%), Positives = 67/151 (44%), Gaps = 2/151 (1%)
Frame = +1
Query: 403 EDRYESNCCPEFIITK-GLHVFNFEFQLPAHLPASFVVPDVPEADCFHAFVIYNIKIEVV 579
ED+ E +I K G H + F F++P +LP S + PE V Y +K
Sbjct: 92 EDKKPLTRLQERLIKKLGEHAYPFTFEIPPNLPCSVTLQPGPEDTGKACGVDYEVKAFCA 151
Query: 580 NVTHQVSHSRERDILVFKSLDLT-QFPKLKDKITLRKEFQISECCASKSKLLCELTVNKC 756
+ H R LV + + + P + ++F +S+ L E +++K
Sbjct: 152 ENLEEKIHKRNSVRLVIRKVQYAPERPGPQPTAETTRQFLMSD-----KPLHLEASLDKE 206
Query: 757 AFVPGEILSVEVLVKNGSAKPIESVQLSLYQ 849
+ GE +SV V V N + K ++ +++S+ Q
Sbjct: 207 IYYHGEPISVNVHVTNNTNKTVKKIKISVRQ 237
>sp|P29067|ARRB2_RAT Beta-arrestin-2 (Arrestin, beta 2)
Length = 410
Score = 44.7 bits (104), Expect = 4e-04
Identities = 34/134 (25%), Positives = 60/134 (44%), Gaps = 1/134 (0%)
Frame = +1
Query: 451 GLHVFNFEFQLPAHLPASFVVPDVPEADCFHAFVIYNIKIEVVNVTHQVSHSRERDILVF 630
G H F F +P +LP S + PE V + I+ + SH R L+
Sbjct: 110 GQHAHPFFFTIPQNLPCSVTLQPGPEDTGKACGVDFEIRAFCAKSIEEKSHKRNSVRLII 169
Query: 631 KSLDLT-QFPKLKDKITLRKEFQISECCASKSKLLCELTVNKCAFVPGEILSVEVLVKNG 807
+ + + P + + F +S+ + L E +++K + GE L+V V V N
Sbjct: 170 RKVQFAPETPGPQPSAETTRHFLMSD----RRSLHLEASLDKELYYHGEPLNVNVHVTNN 225
Query: 808 SAKPIESVQLSLYQ 849
SAK ++ +++S+ Q
Sbjct: 226 SAKTVKKIRVSVRQ 239
>sp|P49407|ARRB1_HUMAN Beta-arrestin-1 (Arrestin, beta 1)
Length = 418
Score = 44.7 bits (104), Expect = 4e-04
Identities = 38/151 (25%), Positives = 67/151 (44%), Gaps = 2/151 (1%)
Frame = +1
Query: 403 EDRYESNCCPEFIITK-GLHVFNFEFQLPAHLPASFVVPDVPEADCFHAFVIYNIKIEVV 579
ED+ E +I K G H + F F++P +LP S + PE V Y +K
Sbjct: 92 EDKKPLTRLQERLIKKLGEHAYPFTFEIPPNLPCSVTLQPGPEDTGKACGVDYEVKAFCA 151
Query: 580 NVTHQVSHSRERDILVFKSLDLT-QFPKLKDKITLRKEFQISECCASKSKLLCELTVNKC 756
+ H R LV + + + P + ++F +S+ L E +++K
Sbjct: 152 ENLEEKIHKRNSVRLVIRKVQYAPERPGPQPTAETTRQFLMSD-----KPLHLEASLDKE 206
Query: 757 AFVPGEILSVEVLVKNGSAKPIESVQLSLYQ 849
+ GE +SV V V N + K ++ +++S+ Q
Sbjct: 207 IYYHGEPISVNVHVTNNTNKTVKKIKISVRQ 237
>sp|P17870|ARRB1_BOVIN Beta-arrestin-1 (Arrestin, beta 1)
Length = 418
Score = 44.7 bits (104), Expect = 4e-04
Identities = 38/151 (25%), Positives = 67/151 (44%), Gaps = 2/151 (1%)
Frame = +1
Query: 403 EDRYESNCCPEFIITK-GLHVFNFEFQLPAHLPASFVVPDVPEADCFHAFVIYNIKIEVV 579
ED+ E +I K G H + F F++P +LP S + PE V Y +K
Sbjct: 92 EDKKPLTRLQERLIKKLGEHAYPFTFEIPPNLPCSVTLQPGPEDTGKACGVDYEVKAFCA 151
Query: 580 NVTHQVSHSRERDILVFKSLDLT-QFPKLKDKITLRKEFQISECCASKSKLLCELTVNKC 756
+ H R LV + + + P + ++F +S+ L E +++K
Sbjct: 152 ENLEEKIHKRNSVRLVIRKVQYAPERPGPQPTAETTRQFLMSD-----KPLHLEASLDKE 206
Query: 757 AFVPGEILSVEVLVKNGSAKPIESVQLSLYQ 849
+ GE +SV V V N + K ++ +++S+ Q
Sbjct: 207 IYYHGEPISVNVHVTNNTNKTVKKIKISVRQ 237
>sp|Q8BWG8|ARRB1_MOUSE Beta-arrestin-1 (Arrestin, beta 1)
Length = 418
Score = 42.7 bits (99), Expect = 0.001
Identities = 38/151 (25%), Positives = 66/151 (43%), Gaps = 2/151 (1%)
Frame = +1
Query: 403 EDRYESNCCPEFIITK-GLHVFNFEFQLPAHLPASFVVPDVPEADCFHAFVIYNIKIEVV 579
ED+ E +I K G H F F++P +LP S + PE V Y +K
Sbjct: 92 EDKKPLTRLQERLIKKLGEHACPFTFEIPPNLPCSVTLQPGPEDTGKACGVDYEVKAFCA 151
Query: 580 NVTHQVSHSRERDILVFKSLDLT-QFPKLKDKITLRKEFQISECCASKSKLLCELTVNKC 756
+ H R LV + + + P + ++F +S+ L E +++K
Sbjct: 152 ENLEEKIHKRNSVRLVIRKVQYAPERPGPQPTAETTRQFLMSD-----KPLHLEASLDKE 206
Query: 757 AFVPGEILSVEVLVKNGSAKPIESVQLSLYQ 849
+ GE +SV V V N + K ++ +++S+ Q
Sbjct: 207 IYYHGEPISVNVHVTNNTNKTVKKIKISVRQ 237
>sp|P32121|ARRB2_HUMAN Beta-arrestin-2 (Arrestin, beta 2)
Length = 409
Score = 42.0 bits (97), Expect = 0.002
Identities = 34/134 (25%), Positives = 58/134 (43%), Gaps = 1/134 (0%)
Frame = +1
Query: 451 GLHVFNFEFQLPAHLPASFVVPDVPEADCFHAFVIYNIKIEVVNVTHQVSHSRERDILVF 630
G H F F +P +LP S + PE V + I+ + SH R LV
Sbjct: 110 GQHAHPFFFTIPQNLPCSVTLQPGPEDTGKACGVDFEIRAFCAKSLEEKSHKRNSVRLVI 169
Query: 631 KSLDLT-QFPKLKDKITLRKEFQISECCASKSKLLCELTVNKCAFVPGEILSVEVLVKNG 807
+ + + P + + F +S+ L E +++K + GE L+V V V N
Sbjct: 170 RKVQFAPEKPGPQPSAETTRHFLMSD-----RSLHLEASLDKELYYHGEPLNVNVHVTNN 224
Query: 808 SAKPIESVQLSLYQ 849
S K ++ +++S+ Q
Sbjct: 225 STKTVKKIKVSVRQ 238
>sp|P32120|ARRB2_BOVIN Beta-arrestin-2 (Arrestin, beta 2) (Arrestin-3)
Length = 420
Score = 42.0 bits (97), Expect = 0.002
Identities = 34/134 (25%), Positives = 58/134 (43%), Gaps = 1/134 (0%)
Frame = +1
Query: 451 GLHVFNFEFQLPAHLPASFVVPDVPEADCFHAFVIYNIKIEVVNVTHQVSHSRERDILVF 630
G H F F +P +LP S + PE V + I+ + SH R LV
Sbjct: 110 GQHAHPFFFTIPQNLPCSVTLQPGPEDTGKACGVDFEIRAFCAKSLEEKSHKRNSVRLVI 169
Query: 631 KSLDLT-QFPKLKDKITLRKEFQISECCASKSKLLCELTVNKCAFVPGEILSVEVLVKNG 807
+ + + P + + F +S+ L E +++K + GE L+V V V N
Sbjct: 170 RKVQFAPEKPGPQPSAETTRHFLMSD-----RSLHLEASLDKELYYHGEPLNVNVHVTNN 224
Query: 808 SAKPIESVQLSLYQ 849
S K ++ +++S+ Q
Sbjct: 225 STKTVKKIKVSVRQ 238
>sp|P55274|ARRH_HELVI ARRESTIN HOMOLOG
Length = 381
Score = 40.4 bits (93), Expect = 0.007
Identities = 39/148 (26%), Positives = 66/148 (44%), Gaps = 2/148 (1%)
Frame = +1
Query: 412 YESNCCPEFIITK-GLHVFNFEFQLPAHLPASFVVPDVPEADCFHAFVIYNIKIEVVNVT 588
YE + E +I K G F +P P S ++ E D V Y +KI V +
Sbjct: 94 YELSRTQERLIKKLGDGAIPFRLTVPPGAPGSVILQPGLEDDGEPCGVQYYVKIFVGDSE 153
Query: 589 HQVSHSRERDILVFKSLDLTQF-PKLKDKITLRKEFQISECCASKSKLLCELTVNKCAFV 765
SH R L + + P + +RK+F +S +L ELT++K ++
Sbjct: 154 IDRSHRRSTVALGIRKVQYAPAKPGPQPCTVVRKDFVLSP-----GQLELELTLDKQLYI 208
Query: 766 PGEILSVEVLVKNGSAKPIESVQLSLYQ 849
GE ++V + V+N S K ++ ++ + Q
Sbjct: 209 HGETVAVNMCVRNHSNKVVKKIKACIQQ 236
>sp|P15372|ARRA_DROME Phosrestin-2 (Phosrestin II) (Arrestin A) (Arrestin-1)
Length = 364
Score = 40.0 bits (92), Expect = 0.009
Identities = 36/137 (26%), Positives = 62/137 (45%), Gaps = 4/137 (2%)
Frame = +1
Query: 451 GLHVFNFEFQLPAHLPASFVVPDVPEADCFHAFVIYNIKIEVVNVTHQVSHSRERDILVF 630
G + + F Q+P PAS V+ + V Y +KI + SH R L
Sbjct: 108 GSNAYPFVMQMPPSSPASVVLQQKASDESQPCGVQYFVKIFTGDSDCDRSHRRSTINLGI 167
Query: 631 KSLDLTQFPKLKDKI----TLRKEFQISECCASKSKLLCELTVNKCAFVPGEILSVEVLV 798
+ + Q+ K I +RK+F + S +L E+T++K + GE +SV + V
Sbjct: 168 RKV---QYAPTKQGIQPCTVVRKDFLL-----SPGELELEVTLDKQLYHHGEKISVNICV 219
Query: 799 KNGSAKPIESVQLSLYQ 849
+N S K ++ ++ + Q
Sbjct: 220 RNNSNKVVKKIKAMVQQ 236
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 99,555,500
Number of Sequences: 369166
Number of extensions: 1946735
Number of successful extensions: 4837
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4667
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4834
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 9606826000
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)