Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_008_L18
(393 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q94981|ARI1_DROME Ariadne-1 protein (Ari-1) 178 3e-45
sp|Q9Y4X5|ARI1_HUMAN Ariadne-1 protein homolog (ARI-1) (Ubi... 174 7e-44
sp|Q9Z1K5|ARI1_MOUSE Ariadne-1 protein homolog (ARI-1) (Ubi... 174 7e-44
sp|O95376|ARI2_HUMAN Ariadne-2 protein homolog (ARI-2) (Tri... 65 6e-11
sp|Q9Z1K6|ARI2_MOUSE Ariadne-2 protein homolog (ARI-2) (Tri... 65 6e-11
sp|O76924|ARI2_DROME Ariadne-2 protein (Ari-2) 64 1e-10
sp|Q22431|ARI2_CAEEL Probable ariadne-2 protein (Ari-2) 57 1e-08
sp|P36113|YKZ7_YEAST Hypothetical 63.6 kDa protein in YPT52... 46 2e-05
sp|Q6ZPS6|AKIB1_MOUSE Ankyrin repeat and IBR domain contain... 41 0.001
sp|Q9P2G1|AKIB1_HUMAN Ankyrin repeat and IBR domain contain... 41 0.001
>sp|Q94981|ARI1_DROME Ariadne-1 protein (Ari-1)
Length = 503
Score = 178 bits (452), Expect = 3e-45
Identities = 80/107 (74%), Positives = 96/107 (89%)
Frame = +1
Query: 1 MSWIEVQFLKQAVDVLCDCRRTLNYTYVFAYYLKKNNQSIIFEGNQSDLEQSTEQLSEYL 180
MSWIEVQFLK+AVD+LC CR+TL YTYVFAYYLKKNNQS+IFE NQ DLE +TE LSEYL
Sbjct: 397 MSWIEVQFLKKAVDILCQCRQTLMYTYVFAYYLKKNNQSMIFEDNQKDLESATEMLSEYL 456
Query: 181 ERDITTDSLVDIKQRVQDKTRYCKQRRAVLLKHVHEGYENDWWEHLD 321
ERDIT+++L DIKQ+VQDK RYC++R +VLLKHVHEGY+ +WWE+ +
Sbjct: 457 ERDITSENLADIKQKVQDKYRYCEKRCSVLLKHVHEGYDKEWWEYTE 503
>sp|Q9Y4X5|ARI1_HUMAN Ariadne-1 protein homolog (ARI-1) (Ubiquitin-conjugating enzyme
E2-binding protein 1) (UbcH7-binding protein)
(UbcM4-interacting protein) (HHARI) (H7-AP2) (MOP-6)
Length = 557
Score = 174 bits (440), Expect = 7e-44
Identities = 82/107 (76%), Positives = 93/107 (86%)
Frame = +1
Query: 1 MSWIEVQFLKQAVDVLCDCRRTLNYTYVFAYYLKKNNQSIIFEGNQSDLEQSTEQLSEYL 180
MSWIEVQFLK+AVDVLC CR TL YTYVFA+YLKKNNQSIIFE NQ+DLE +TE LS YL
Sbjct: 450 MSWIEVQFLKKAVDVLCQCRATLMYTYVFAFYLKKNNQSIIFENNQADLENATEVLSGYL 509
Query: 181 ERDITTDSLVDIKQRVQDKTRYCKQRRAVLLKHVHEGYENDWWEHLD 321
ERDI+ DSL DIKQ+VQDK RYC+ RR VLL+HVHEGYE D WE+++
Sbjct: 510 ERDISQDSLQDIKQKVQDKYRYCESRRRVLLQHVHEGYEKDLWEYIE 556
>sp|Q9Z1K5|ARI1_MOUSE Ariadne-1 protein homolog (ARI-1) (Ubiquitin-conjugating enzyme
E2-binding protein 1) (UbcH7-binding protein)
(UbcM4-interacting protein 77)
Length = 555
Score = 174 bits (440), Expect = 7e-44
Identities = 82/107 (76%), Positives = 93/107 (86%)
Frame = +1
Query: 1 MSWIEVQFLKQAVDVLCDCRRTLNYTYVFAYYLKKNNQSIIFEGNQSDLEQSTEQLSEYL 180
MSWIEVQFLK+AVDVLC CR TL YTYVFA+YLKKNNQSIIFE NQ+DLE +TE LS YL
Sbjct: 448 MSWIEVQFLKKAVDVLCQCRATLMYTYVFAFYLKKNNQSIIFENNQADLENATEVLSGYL 507
Query: 181 ERDITTDSLVDIKQRVQDKTRYCKQRRAVLLKHVHEGYENDWWEHLD 321
ERDI+ DSL DIKQ+VQDK RYC+ RR VLL+HVHEGYE D WE+++
Sbjct: 508 ERDISQDSLQDIKQKVQDKYRYCESRRRVLLQHVHEGYEKDLWEYIE 554
>sp|O95376|ARI2_HUMAN Ariadne-2 protein homolog (ARI-2) (Triad1 protein)
Length = 493
Score = 64.7 bits (156), Expect = 6e-11
Identities = 34/95 (35%), Positives = 54/95 (56%)
Frame = +1
Query: 4 SWIEVQFLKQAVDVLCDCRRTLNYTYVFAYYLKKNNQSIIFEGNQSDLEQSTEQLSEYLE 183
+WI+ Q+L+ A +L CR TL YTY +AYY++ + +FE Q+ LE E LS +E
Sbjct: 403 TWIDWQYLQNAAKLLAKCRYTLQYTYPYAYYMESGPRKKLFEYQQAQLEAEIENLSWKVE 462
Query: 184 RDITTDSLVDIKQRVQDKTRYCKQRRAVLLKHVHE 288
R + D + ++++ +QRR LLK H+
Sbjct: 463 RADSYD-----RGDLENQMHIAEQRRRTLLKDFHD 492
>sp|Q9Z1K6|ARI2_MOUSE Ariadne-2 protein homolog (ARI-2) (Triad1 protein)
(UbcM4-interacting protein 48)
Length = 492
Score = 64.7 bits (156), Expect = 6e-11
Identities = 34/95 (35%), Positives = 54/95 (56%)
Frame = +1
Query: 4 SWIEVQFLKQAVDVLCDCRRTLNYTYVFAYYLKKNNQSIIFEGNQSDLEQSTEQLSEYLE 183
+WI+ Q+L+ A +L CR TL YTY +AYY++ + +FE Q+ LE E LS +E
Sbjct: 402 TWIDWQYLQNAAKLLAKCRYTLQYTYPYAYYMESGPRKKLFEYQQAQLEAEIENLSWKVE 461
Query: 184 RDITTDSLVDIKQRVQDKTRYCKQRRAVLLKHVHE 288
R + D + ++++ +QRR LLK H+
Sbjct: 462 RADSYD-----RGDLENQMHIAEQRRRTLLKDFHD 491
>sp|O76924|ARI2_DROME Ariadne-2 protein (Ari-2)
Length = 509
Score = 63.5 bits (153), Expect = 1e-10
Identities = 36/91 (39%), Positives = 54/91 (59%)
Frame = +1
Query: 4 SWIEVQFLKQAVDVLCDCRRTLNYTYVFAYYLKKNNQSIIFEGNQSDLEQSTEQLSEYLE 183
+WI+ Q+L A +L CR TL YTY +AYY++ ++ +FE Q+ LE E LS +E
Sbjct: 417 TWIDWQYLFNAAALLAKCRYTLQYTYPYAYYMEAGSRKNLFEYQQAQLEAEIENLSWKIE 476
Query: 184 RDITTDSLVDIKQRVQDKTRYCKQRRAVLLK 276
R TTD L D++ ++ ++RR LLK
Sbjct: 477 RAETTD-LGDLENQMD----IAEKRRTTLLK 502
>sp|Q22431|ARI2_CAEEL Probable ariadne-2 protein (Ari-2)
Length = 482
Score = 57.0 bits (136), Expect = 1e-08
Identities = 26/61 (42%), Positives = 40/61 (65%)
Frame = +1
Query: 4 SWIEVQFLKQAVDVLCDCRRTLNYTYVFAYYLKKNNQSIIFEGNQSDLEQSTEQLSEYLE 183
+WI+ Q+L ++V +L CR TL YTY FAY+L + +FE Q+ LE+ E+L+ +E
Sbjct: 393 TWIDWQYLHKSVSLLTKCRYTLQYTYPFAYFLSATPRKNLFEYQQAQLEKEVEELAWAVE 452
Query: 184 R 186
R
Sbjct: 453 R 453
>sp|P36113|YKZ7_YEAST Hypothetical 63.6 kDa protein in YPT52-GCN3 intergenic region
Length = 551
Score = 46.2 bits (108), Expect = 2e-05
Identities = 29/93 (31%), Positives = 50/93 (53%), Gaps = 1/93 (1%)
Frame = +1
Query: 1 MSWIEVQFLKQAVDVLCDCRRTLNYTYVFAYYL-KKNNQSIIFEGNQSDLEQSTEQLSEY 177
+SWI+ QFL +++ VL + R L +++ AYY +N + IF NQ L + E LSE
Sbjct: 445 ISWIDGQFLSESLKVLNEGRTVLKWSFAVAYYSDASHNLTKIFVDNQMLLANAVESLSEL 504
Query: 178 LERDITTDSLVDIKQRVQDKTRYCKQRRAVLLK 276
L+ T + ++ + +K Y + R L++
Sbjct: 505 LQIK-TPEVIMKRRPEFYNKAGYVENRTTALME 536
>sp|Q6ZPS6|AKIB1_MOUSE Ankyrin repeat and IBR domain containing protein 1
Length = 1087
Score = 40.8 bits (94), Expect = 0.001
Identities = 22/59 (37%), Positives = 36/59 (61%), Gaps = 1/59 (1%)
Frame = +1
Query: 13 EVQFLKQAVDVLCDCRRTLNYTYVFAYYLK-KNNQSIIFEGNQSDLEQSTEQLSEYLER 186
+ F++ AV VL RR L +Y + ++L+ K+ + IFE Q+DLE TE L++ + R
Sbjct: 645 DTTFIEDAVHVLLKTRRILKCSYPYGFFLEPKSTKKEIFELMQTDLEMVTEDLAQKVNR 703
>sp|Q9P2G1|AKIB1_HUMAN Ankyrin repeat and IBR domain containing protein 1
Length = 1214
Score = 40.8 bits (94), Expect = 0.001
Identities = 22/59 (37%), Positives = 36/59 (61%), Gaps = 1/59 (1%)
Frame = +1
Query: 13 EVQFLKQAVDVLCDCRRTLNYTYVFAYYLK-KNNQSIIFEGNQSDLEQSTEQLSEYLER 186
+ F++ AV VL RR L +Y + ++L+ K+ + IFE Q+DLE TE L++ + R
Sbjct: 767 DTTFIEDAVHVLLKTRRILKCSYPYGFFLEPKSTKKEIFELMQTDLEMVTEDLAQKVNR 825
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 39,674,410
Number of Sequences: 369166
Number of extensions: 713237
Number of successful extensions: 2600
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2532
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2600
length of database: 68,354,980
effective HSP length: 96
effective length of database: 50,620,420
effective search space used: 1721094280
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)