Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_008_K14
(364 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P80067|CATC_RAT Dipeptidyl-peptidase I precursor (DPP-I)... 69 4e-12
sp|Q60HG6|CATC_MACFA Dipeptidyl-peptidase I precursor (DPP-... 68 6e-12
sp|Q26563|CATC_SCHMA Cathepsin C precursor 68 8e-12
sp|P53634|CATC_HUMAN Dipeptidyl-peptidase I precursor (DPP-... 67 1e-11
sp|P97821|CATC_MOUSE Dipeptidyl-peptidase I precursor (DPP-... 67 1e-11
sp|O97578|CATC_CANFA Dipeptidyl-peptidase I precursor (DPP-... 63 2e-10
sp|Q8IIJ9|CATC_PLAF7 Probable cathepsin C precursor 49 5e-06
sp|P80884|ANAN_ANACO Ananain precursor 44 9e-05
sp|P92131|CATB1_GIALA Cathepsin B-like CP1 precursor (Cathe... 44 1e-04
sp|P43510|CPR6_CAEEL Cathepsin B-like cysteine proteinase 6... 41 8e-04
>sp|P80067|CATC_RAT Dipeptidyl-peptidase I precursor (DPP-I) (DPPI) (Cathepsin C)
(Cathepsin J) (Dipeptidyl transferase) [Contains:
Dipeptidyl-peptidase I exclusion domain chain;
Dipeptidyl-peptidase I heavy chain; Dipeptidyl-peptidase
I light chain]
Length = 462
Score = 68.6 bits (166), Expect = 4e-12
Identities = 37/76 (48%), Positives = 48/76 (63%), Gaps = 1/76 (1%)
Frame = +1
Query: 1 GPIAVGFEVYDDFMSYSGGVYHHNFGTRKLTTSKFGFNPFELTNHAVLVVGSGKPP-PER 177
GP+AV FEV+DDF+ Y G+YHH T FNPFELTNHAVL+VG GK P
Sbjct: 367 GPMAVAFEVHDDFLHYHSGIYHH-------TGLSDPFNPFELTNHAVLLVGYGKDPVTGL 419
Query: 178 NFGMVKTVGGTEGVET 225
++ +VK G++ E+
Sbjct: 420 DYWIVKNSWGSQWGES 435
Score = 45.4 bits (106), Expect = 4e-05
Identities = 22/43 (51%), Positives = 27/43 (62%)
Frame = +3
Query: 168 SGKKFWNGKNSWGNGRGGNGYFRIPRGNDEWGIQRPGGAAEPI 296
+G +W KNSWG+ G +GYFRI RG DE I+ AA PI
Sbjct: 417 TGLDYWIVKNSWGSQWGESGYFRIRRGTDECAIESIAMAAIPI 459
>sp|Q60HG6|CATC_MACFA Dipeptidyl-peptidase I precursor (DPP-I) (DPPI) (Cathepsin C)
(Cathepsin J) (Dipeptidyl transferase) [Contains:
Dipeptidyl-peptidase I exclusion domain chain;
Dipeptidyl-peptidase I heavy chain; Dipeptidyl-peptidase
I light chain]
Length = 463
Score = 68.2 bits (165), Expect = 6e-12
Identities = 36/71 (50%), Positives = 44/71 (61%), Gaps = 1/71 (1%)
Frame = +1
Query: 1 GPIAVGFEVYDDFMSYSGGVYHHNFGTRKLTTSKFGFNPFELTNHAVLVVGSGKPPPE-R 177
GP+AV FEVYDDF+ Y G+YHH T + FNPFELTNHAVL+VG G
Sbjct: 368 GPLAVAFEVYDDFLHYQNGIYHH-------TGLRDPFNPFELTNHAVLLVGYGTDSASGM 420
Query: 178 NFGMVKTVGGT 210
++ +VK GT
Sbjct: 421 DYWIVKNSWGT 431
Score = 49.7 bits (117), Expect = 2e-06
Identities = 23/46 (50%), Positives = 29/46 (63%)
Frame = +3
Query: 159 ETSSGKKFWNGKNSWGNGRGGNGYFRIPRGNDEWGIQRPGGAAEPI 296
+++SG +W KNSWG G +GYFRI RG DE I+ AA PI
Sbjct: 415 DSASGMDYWIVKNSWGTSWGEDGYFRIRRGTDECAIESIAVAATPI 460
>sp|Q26563|CATC_SCHMA Cathepsin C precursor
Length = 454
Score = 67.8 bits (164), Expect = 8e-12
Identities = 31/53 (58%), Positives = 36/53 (67%)
Frame = +1
Query: 1 GPIAVGFEVYDDFMSYSGGVYHHNFGTRKLTTSKFGFNPFELTNHAVLVVGSG 159
GP VGFEVY+DF Y G+YHH + T + FNPFELTNHAVL+VG G
Sbjct: 358 GPFPVGFEVYEDFQFYKEGIYHHT----TVQTDHYNFNPFELTNHAVLLVGYG 406
Score = 49.7 bits (117), Expect = 2e-06
Identities = 22/44 (50%), Positives = 28/44 (63%)
Frame = +3
Query: 168 SGKKFWNGKNSWGNGRGGNGYFRIPRGNDEWGIQRPGGAAEPIL 299
SG+ +W KNSWG G GYFRI RG DE G++ G +P+L
Sbjct: 411 SGEPYWKVKNSWGVEWGEQGYFRILRGTDECGVESLGVRFDPVL 454
>sp|P53634|CATC_HUMAN Dipeptidyl-peptidase I precursor (DPP-I) (DPPI) (Cathepsin C)
(Cathepsin J) (Dipeptidyl transferase) [Contains:
Dipeptidyl-peptidase I exclusion domain chain;
Dipeptidyl-peptidase I heavy chain; Dipeptidyl-peptidase
I light chain]
Length = 463
Score = 67.0 bits (162), Expect = 1e-11
Identities = 36/71 (50%), Positives = 44/71 (61%), Gaps = 1/71 (1%)
Frame = +1
Query: 1 GPIAVGFEVYDDFMSYSGGVYHHNFGTRKLTTSKFGFNPFELTNHAVLVVGSGKPPPE-R 177
GP+AV FEVYDDF+ Y G+YHH T + FNPFELTNHAVL+VG G
Sbjct: 368 GPMAVAFEVYDDFLHYKKGIYHH-------TGLRDPFNPFELTNHAVLLVGYGTDSASGM 420
Query: 178 NFGMVKTVGGT 210
++ +VK GT
Sbjct: 421 DYWIVKNSWGT 431
Score = 53.9 bits (128), Expect = 1e-07
Identities = 25/46 (54%), Positives = 30/46 (65%)
Frame = +3
Query: 159 ETSSGKKFWNGKNSWGNGRGGNGYFRIPRGNDEWGIQRPGGAAEPI 296
+++SG +W KNSWG G G NGYFRI RG DE I+ AA PI
Sbjct: 415 DSASGMDYWIVKNSWGTGWGENGYFRIRRGTDECAIESIAVAATPI 460
>sp|P97821|CATC_MOUSE Dipeptidyl-peptidase I precursor (DPP-I) (DPPI) (Cathepsin C)
(Cathepsin J) (Dipeptidyl transferase) [Contains:
Dipeptidyl-peptidase I exclusion domain chain;
Dipeptidyl-peptidase I heavy chain; Dipeptidyl-peptidase
I light chain]
Length = 462
Score = 67.0 bits (162), Expect = 1e-11
Identities = 32/56 (57%), Positives = 38/56 (67%)
Frame = +1
Query: 1 GPIAVGFEVYDDFMSYSGGVYHHNFGTRKLTTSKFGFNPFELTNHAVLVVGSGKPP 168
GP+AV FEV+DDF+ Y G+YHH T FNPFELTNHAVL+VG G+ P
Sbjct: 367 GPMAVAFEVHDDFLHYHSGIYHH-------TGLSDPFNPFELTNHAVLLVGYGRDP 415
Score = 46.2 bits (108), Expect = 2e-05
Identities = 22/43 (51%), Positives = 28/43 (65%)
Frame = +3
Query: 168 SGKKFWNGKNSWGNGRGGNGYFRIPRGNDEWGIQRPGGAAEPI 296
+G ++W KNSWG+ G +GYFRI RG DE I+ AA PI
Sbjct: 417 TGIEYWIIKNSWGSNWGESGYFRIRRGTDECAIESIAVAAIPI 459
>sp|O97578|CATC_CANFA Dipeptidyl-peptidase I precursor (DPP-I) (DPPI) (Cathepsin C)
(Cathepsin J) (Dipeptidyl transferase) [Contains:
Dipeptidyl-peptidase I exclusion domain chain;
Dipeptidyl-peptidase I heavy chain 1;
Dipeptidyl-peptidase I heavy chain 2;
Dipeptidyl-peptidase I heavy chain 3;
Dipeptidyl-peptidase I heavy chain 4;
Dipeptidyl-peptidase I light chain]
Length = 435
Score = 63.2 bits (152), Expect = 2e-10
Identities = 31/53 (58%), Positives = 36/53 (67%)
Frame = +1
Query: 1 GPIAVGFEVYDDFMSYSGGVYHHNFGTRKLTTSKFGFNPFELTNHAVLVVGSG 159
GP+AV FEVYDDF Y G+Y+H T + FNPFELTNHAVL+VG G
Sbjct: 340 GPMAVAFEVYDDFFHYQKGIYYH-------TGLRDPFNPFELTNHAVLLVGYG 385
Score = 49.3 bits (116), Expect = 3e-06
Identities = 23/46 (50%), Positives = 30/46 (65%)
Frame = +3
Query: 159 ETSSGKKFWNGKNSWGNGRGGNGYFRIPRGNDEWGIQRPGGAAEPI 296
+++SG +W KNSWG+ G +GYFRI RG DE I+ AA PI
Sbjct: 387 DSASGMDYWIVKNSWGSRWGEDGYFRIRRGTDECAIESIAVAATPI 432
>sp|Q8IIJ9|CATC_PLAF7 Probable cathepsin C precursor
Length = 700
Score = 48.5 bits (114), Expect = 5e-06
Identities = 24/50 (48%), Positives = 30/50 (60%), Gaps = 2/50 (4%)
Frame = +3
Query: 150 WFGETSSGK--KFWNGKNSWGNGRGGNGYFRIPRGNDEWGIQRPGGAAEP 293
W E +GK K+W G+NSWGNG G GYF+I RG + GI+ EP
Sbjct: 631 WGEEEINGKLYKYWIGRNSWGNGWGKEGYFKILRGQNFSGIESQSLFIEP 680
Score = 31.2 bits (69), Expect = 0.78
Identities = 18/61 (29%), Positives = 30/61 (49%), Gaps = 7/61 (11%)
Frame = +1
Query: 1 GPIAVGFEVYDDFMSYSGGVYH-HNFGTRKLTTSK------FGFNPFELTNHAVLVVGSG 159
GPI FE DF Y+ GVY +F + T + + ++ NHA++++G G
Sbjct: 573 GPIVSSFEASPDFYDYADGVYFVEDFPHARRCTIEPKNDGVYNITGWDRVNHAIVLLGWG 632
Query: 160 K 162
+
Sbjct: 633 E 633
>sp|P80884|ANAN_ANACO Ananain precursor
Length = 345
Score = 44.3 bits (103), Expect = 9e-05
Identities = 18/31 (58%), Positives = 22/31 (70%)
Frame = +3
Query: 153 FGETSSGKKFWNGKNSWGNGRGGNGYFRIPR 245
+G+ SSGKKFW +NSWG G G GY R+ R
Sbjct: 286 YGQDSSGKKFWIVRNSWGAGWGEGGYIRLAR 316
Score = 31.2 bits (69), Expect = 0.78
Identities = 18/68 (26%), Positives = 29/68 (42%)
Frame = +1
Query: 4 PIAVGFEVYDDFMSYSGGVYHHNFGTRKLTTSKFGFNPFELTNHAVLVVGSGKPPPERNF 183
PIA + +F Y GV+ GTR NHA++++G G+ + F
Sbjct: 250 PIAAALDASGNFQHYKRGVFTGPCGTR--------------LNHAIVIIGYGQDSSGKKF 295
Query: 184 GMVKTVGG 207
+V+ G
Sbjct: 296 WIVRNSWG 303
>sp|P92131|CATB1_GIALA Cathepsin B-like CP1 precursor (Cathepsin B-like protease B1)
Length = 303
Score = 43.9 bits (102), Expect = 1e-04
Identities = 20/39 (51%), Positives = 24/39 (61%)
Frame = +3
Query: 153 FGETSSGKKFWNGKNSWGNGRGGNGYFRIPRGNDEWGIQ 269
+G T G +W KNSWG G NGYFRI RG +E I+
Sbjct: 256 YGTTDDGTDYWIIKNSWGPDWGENGYFRIVRGVNECRIE 294
Score = 35.0 bits (79), Expect = 0.054
Identities = 22/71 (30%), Positives = 31/71 (43%)
Frame = +1
Query: 1 GPIAVGFEVYDDFMSYSGGVYHHNFGTRKLTTSKFGFNPFELTNHAVLVVGSGKPPPERN 180
GP+ VY D Y GVY H +GT L GF HA+ +VG G +
Sbjct: 217 GPLQTMIVVYADLSYYESGVYKHTYGTINL-----GF-------HALEIVGYGTTDDGTD 264
Query: 181 FGMVKTVGGTE 213
+ ++K G +
Sbjct: 265 YWIIKNSWGPD 275
>sp|P43510|CPR6_CAEEL Cathepsin B-like cysteine proteinase 6 precursor (Cysteine
protease-related 6)
Length = 379
Score = 41.2 bits (95), Expect = 8e-04
Identities = 22/53 (41%), Positives = 29/53 (54%)
Frame = +1
Query: 1 GPIAVGFEVYDDFMSYSGGVYHHNFGTRKLTTSKFGFNPFELTNHAVLVVGSG 159
GP+ + FEVY+DF++Y GGVY H T K G HAV ++G G
Sbjct: 274 GPLEIAFEVYEDFLNYDGGVYVH-------TGGKLG------GGHAVKLIGWG 313
Score = 37.0 bits (84), Expect = 0.014
Identities = 16/33 (48%), Positives = 20/33 (60%)
Frame = +3
Query: 171 GKKFWNGKNSWGNGRGGNGYFRIPRGNDEWGIQ 269
G +W NSW G +G+FRI RG DE GI+
Sbjct: 317 GIPYWTVANSWNTDWGEDGFFRILRGVDECGIE 349
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 51,419,742
Number of Sequences: 369166
Number of extensions: 1230362
Number of successful extensions: 4119
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3667
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4087
length of database: 68,354,980
effective HSP length: 87
effective length of database: 52,283,035
effective search space used: 1725340155
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)