Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= Dr_sW_008_K09 (314 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|P06761|GRP78_RAT 78 kDa glucose-regulated protein precur... 79 2e-15 sp|P11021|GRP78_HUMAN 78 kDa glucose-regulated protein prec... 77 2e-14 sp|P07823|GRP78_MESAU 78 kDa glucose-regulated protein prec... 77 2e-14 sp|P20029|GRP78_MOUSE 78 kDa glucose-regulated protein prec... 76 2e-14 sp|Q90593|GRP78_CHICK 78 kDa glucose-regulated protein prec... 76 2e-14 sp|Q91883|GRP78_XENLA 78 kDa glucose-regulated protein prec... 76 3e-14 sp|Q16956|GRP78_APLCA 78 kDa glucose-regulated protein prec... 75 5e-14 sp|P27420|HSP7C_CAEEL Heat shock 70 kDa protein C precursor 72 3e-13 sp|P19208|HSP7C_CAEBR Heat shock 70 kDa protein C precursor 70 1e-12 sp|P20163|HSP7D_CAEEL Heat shock 70 kDa protein D precursor 67 1e-11
>sp|P06761|GRP78_RAT 78 kDa glucose-regulated protein precursor (GRP 78) (Immunoglobulin heavy chain binding protein) (BiP) (Steroidogenesis-activator polypeptide) Length = 654 Score = 79.3 bits (194), Expect = 2e-15 Identities = 37/59 (62%), Positives = 46/59 (77%) Frame = +3 Query: 3 KLGGKLSPSDKETITKATEEAISWLEKNQQADSEELKAQKKKVEDIVTPIMTKLYQQSG 179 KLGGKLSP DKET+ KA EE I WLE +Q AD E+ KA+KK++E+IV PI++KLY G Sbjct: 581 KLGGKLSPEDKETMEKAVEEKIEWLESHQDADIEDFKAKKKELEEIVQPIISKLYGSGG 639
>sp|P11021|GRP78_HUMAN 78 kDa glucose-regulated protein precursor (GRP 78) (Immunoglobulin heavy chain binding protein) (BiP) (Endoplasmic reticulum lumenal Ca(2+) binding protein grp78) Length = 654 Score = 76.6 bits (187), Expect = 2e-14 Identities = 36/59 (61%), Positives = 46/59 (77%) Frame = +3 Query: 3 KLGGKLSPSDKETITKATEEAISWLEKNQQADSEELKAQKKKVEDIVTPIMTKLYQQSG 179 KLGGKLS DKET+ KA EE I WLE +Q AD E+ KA+KK++E+IV PI++KLY +G Sbjct: 581 KLGGKLSSEDKETMEKAVEEKIEWLESHQDADIEDFKAKKKELEEIVQPIISKLYGSAG 639
>sp|P07823|GRP78_MESAU 78 kDa glucose-regulated protein precursor (GRP 78) (Immunoglobulin heavy chain binding protein) (BiP) Length = 654 Score = 76.6 bits (187), Expect = 2e-14 Identities = 36/59 (61%), Positives = 46/59 (77%) Frame = +3 Query: 3 KLGGKLSPSDKETITKATEEAISWLEKNQQADSEELKAQKKKVEDIVTPIMTKLYQQSG 179 KLGGKLS DKET+ KA EE I WLE +Q AD E+ KA+KK++E+IV PI++KLY +G Sbjct: 581 KLGGKLSSEDKETMEKAVEEKIEWLESHQDADIEDFKAKKKELEEIVQPIISKLYGSAG 639
>sp|P20029|GRP78_MOUSE 78 kDa glucose-regulated protein precursor (GRP 78) (Immunoglobulin heavy chain binding protein) (BiP) Length = 655 Score = 76.3 bits (186), Expect = 2e-14 Identities = 36/59 (61%), Positives = 45/59 (76%) Frame = +3 Query: 3 KLGGKLSPSDKETITKATEEAISWLEKNQQADSEELKAQKKKVEDIVTPIMTKLYQQSG 179 KLGGKLS DKET+ KA EE I WLE +Q AD E+ KA+KK++E+IV PI++KLY G Sbjct: 582 KLGGKLSSEDKETMEKAVEEKIEWLESHQDADIEDFKAKKKELEEIVQPIISKLYGSGG 640
>sp|Q90593|GRP78_CHICK 78 kDa glucose-regulated protein precursor (GRP 78) (Immunoglobulin heavy chain binding protein) (BiP) Length = 652 Score = 76.3 bits (186), Expect = 2e-14 Identities = 35/59 (59%), Positives = 46/59 (77%) Frame = +3 Query: 3 KLGGKLSPSDKETITKATEEAISWLEKNQQADSEELKAQKKKVEDIVTPIMTKLYQQSG 179 KLGGKLS DKETI KA EE I WLE +Q AD E+ K++KK++E++V PI++KLY +G Sbjct: 579 KLGGKLSSEDKETIEKAVEEKIEWLESHQDADIEDFKSKKKELEEVVQPIVSKLYGSAG 637
>sp|Q91883|GRP78_XENLA 78 kDa glucose-regulated protein precursor (GRP 78) (Immunoglobulin heavy chain binding protein) (BiP) Length = 658 Score = 75.9 bits (185), Expect = 3e-14 Identities = 37/59 (62%), Positives = 45/59 (76%) Frame = +3 Query: 3 KLGGKLSPSDKETITKATEEAISWLEKNQQADSEELKAQKKKVEDIVTPIMTKLYQQSG 179 KLGGKLS DKETI KA EE I WLE +Q AD E+ KA+KK++E+IV PI+ KLY +G Sbjct: 582 KLGGKLSSEDKETIEKAVEEKIEWLESHQDADIEDFKAKKKELEEIVQPIVGKLYGGAG 640
>sp|Q16956|GRP78_APLCA 78 kDa glucose-regulated protein precursor (GRP 78) (BiP) (Protein 1603) Length = 667 Score = 75.1 bits (183), Expect = 5e-14 Identities = 36/59 (61%), Positives = 44/59 (74%) Frame = +3 Query: 3 KLGGKLSPSDKETITKATEEAISWLEKNQQADSEELKAQKKKVEDIVTPIMTKLYQQSG 179 KLG KLS DKE IT+A +EAI WLE N +A+SE +K ++E IV PIMTKLY+QSG Sbjct: 590 KLGAKLSDEDKEKITEAVDEAIKWLESNAEAESEAFNEKKTELEGIVQPIMTKLYEQSG 648
>sp|P27420|HSP7C_CAEEL Heat shock 70 kDa protein C precursor Length = 661 Score = 72.4 bits (176), Expect = 3e-13 Identities = 35/59 (59%), Positives = 44/59 (74%) Frame = +3 Query: 3 KLGGKLSPSDKETITKATEEAISWLEKNQQADSEELKAQKKKVEDIVTPIMTKLYQQSG 179 KLGGKL DK+TI +A EEAISWL N +A +EELK QKK +E V PI++KLY+ +G Sbjct: 586 KLGGKLDEDDKKTIEEAVEEAISWLGSNAEASAEELKEQKKDLESKVQPIVSKLYKDAG 644
>sp|P19208|HSP7C_CAEBR Heat shock 70 kDa protein C precursor Length = 661 Score = 70.5 bits (171), Expect = 1e-12 Identities = 34/59 (57%), Positives = 43/59 (72%) Frame = +3 Query: 3 KLGGKLSPSDKETITKATEEAISWLEKNQQADSEELKAQKKKVEDIVTPIMTKLYQQSG 179 KLGGKL DK+TI +A +EAISWL N A +EELK QKK++E V PI++KLY+ G Sbjct: 586 KLGGKLDEDDKKTIEEAVDEAISWLGSNADASAEELKEQKKELEGKVQPIVSKLYKDGG 644
>sp|P20163|HSP7D_CAEEL Heat shock 70 kDa protein D precursor Length = 657 Score = 67.0 bits (162), Expect = 1e-11 Identities = 32/59 (54%), Positives = 40/59 (67%) Frame = +3 Query: 3 KLGGKLSPSDKETITKATEEAISWLEKNQQADSEELKAQKKKVEDIVTPIMTKLYQQSG 179 KLGGKL+ DK +I A E AI WL NQ A +EE K QKK++E +V PI++KLY G Sbjct: 583 KLGGKLTDEDKVSIESAVERAIEWLGSNQDASTEENKEQKKELESVVQPIVSKLYSAGG 641
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 27,821,048 Number of Sequences: 369166 Number of extensions: 379800 Number of successful extensions: 1729 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 1706 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 1729 length of database: 68,354,980 effective HSP length: 73 effective length of database: 54,869,325 effective search space used: 1700949075 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)