Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= Dr_sW_008_I11 (500 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q9VNA0|TI17A_DROME Probable mitochondrial import inner m... 116 3e-26 sp|O60830|TI17B_HUMAN Mitochondrial import inner membrane t... 114 1e-25 sp|Q99595|TI17A_HUMAN Mitochondrial import inner membrane t... 113 3e-25 sp|Q9Z0V8|TI17A_MOUSE Mitochondrial import inner membrane t... 111 8e-25 sp|Q9VGA2|TI17C_DROME Probable mitochondrial import inner m... 111 1e-24 sp|Q9Z0V7|TI17B_MOUSE Mitochondrial import inner membrane t... 110 1e-24 sp|O35092|TI17A_RAT Mitochondrial import inner membrane tra... 110 1e-24 sp|P39515|TIM17_YEAST Mitochondrial import inner membrane t... 107 1e-23 sp|O44477|TIM17_CAEEL Probable mitochondrial import inner m... 104 1e-22 sp|Q9VN97|TI17D_DROME Probable mitochondrial import inner m... 103 3e-22
>sp|Q9VNA0|TI17A_DROME Probable mitochondrial import inner membrane translocase subunit Tim17 1 Length = 179 Score = 116 bits (290), Expect = 3e-26 Identities = 56/131 (42%), Positives = 80/131 (61%) Frame = +3 Query: 54 FNFVAGFKDAPSGLSKRLISAATRCKIRSPVLGGSFAMWGGTFSCVDCALIYGRKKEDPI 233 F + GF++APSGL RL + RS ++GG+FA+WG TFS +DC+L+Y RKKEDP Sbjct: 31 FQAIKGFRNAPSGLGYRLSGGLAAVRARSGLVGGNFAVWGATFSAIDCSLVYFRKKEDPW 90 Query: 234 NSILAGGITGGVLAIRGGWSQVAGQAFVGAVLLGIIEGCGILFQRFSTQAIVEESMPDNN 413 N+I++G TGG+LA R G + + A VG LL +IEG GI+ +S + + S + Sbjct: 91 NAIISGATTGGILAARTGLTSMLSSALVGGALLALIEGVGIVVSHYSADSYRQVSPVERQ 150 Query: 414 QTISHQSLGLQ 446 Q + L Q Sbjct: 151 QRYKQELLRQQ 161
>sp|O60830|TI17B_HUMAN Mitochondrial import inner membrane translocase subunit Tim17 B (JM3) Length = 172 Score = 114 bits (285), Expect = 1e-25 Identities = 54/110 (49%), Positives = 74/110 (67%) Frame = +3 Query: 51 LFNFVAGFKDAPSGLSKRLISAATRCKIRSPVLGGSFAMWGGTFSCVDCALIYGRKKEDP 230 +F + GF++AP G+ RL +A +IR+P +GGSFA+WGG FS +DC L+ R KEDP Sbjct: 30 VFQAIKGFRNAPVGIRHRLRGSANAVRIRAPQIGGSFAVWGGLFSTIDCGLVRLRGKEDP 89 Query: 231 INSILAGGITGGVLAIRGGWSQVAGQAFVGAVLLGIIEGCGILFQRFSTQ 380 NSI +G +TG VLA R G + G A +G +LL +IEG GIL R++ Q Sbjct: 90 WNSITSGALTGAVLAARSGPLAMVGSAMMGGILLALIEGVGILLTRYTAQ 139
>sp|Q99595|TI17A_HUMAN Mitochondrial import inner membrane translocase subunit Tim17 A (Inner membrane preprotein translocase Tim17a) Length = 171 Score = 113 bits (282), Expect = 3e-25 Identities = 52/109 (47%), Positives = 75/109 (68%) Frame = +3 Query: 51 LFNFVAGFKDAPSGLSKRLISAATRCKIRSPVLGGSFAMWGGTFSCVDCALIYGRKKEDP 230 +F + GF+++P G++ RL + T K R+P LGGSFA+WGG FS +DC+++ R KEDP Sbjct: 30 IFQAIKGFRNSPVGVNHRLRGSLTAIKTRAPQLGGSFAVWGGLFSMIDCSMVQVRGKEDP 89 Query: 231 INSILAGGITGGVLAIRGGWSQVAGQAFVGAVLLGIIEGCGILFQRFST 377 NSI +G +TG +LA R G + G A +G +LL +IEG GIL RF++ Sbjct: 90 WNSITSGALTGAILAARNGPVAMVGSAAMGGILLALIEGAGILLTRFAS 138
>sp|Q9Z0V8|TI17A_MOUSE Mitochondrial import inner membrane translocase subunit Tim17 A (Inner membrane preprotein translocase Tim17a) Length = 171 Score = 111 bits (278), Expect = 8e-25 Identities = 52/109 (47%), Positives = 74/109 (67%) Frame = +3 Query: 51 LFNFVAGFKDAPSGLSKRLISAATRCKIRSPVLGGSFAMWGGTFSCVDCALIYGRKKEDP 230 +F GF+++P G++ RL + T K R+P LGGSFA+WGG FS +DC+++ R KEDP Sbjct: 30 IFQAFKGFRNSPVGINHRLRGSLTAIKTRAPQLGGSFAVWGGLFSTIDCSMVQIRGKEDP 89 Query: 231 INSILAGGITGGVLAIRGGWSQVAGQAFVGAVLLGIIEGCGILFQRFST 377 NSI +G +TG +LA R G + G A +G +LL +IEG GIL RF++ Sbjct: 90 WNSITSGALTGAILAARNGPVAMVGSAAMGGILLALIEGAGILLTRFAS 138
>sp|Q9VGA2|TI17C_DROME Probable mitochondrial import inner membrane translocase subunit Tim17 3 Length = 222 Score = 111 bits (277), Expect = 1e-24 Identities = 52/101 (51%), Positives = 71/101 (70%) Frame = +3 Query: 51 LFNFVAGFKDAPSGLSKRLISAATRCKIRSPVLGGSFAMWGGTFSCVDCALIYGRKKEDP 230 LF F+ GF++AP+GL +RL K+R+P + GSFA+WG TFS VDCAL++ R++ED Sbjct: 29 LFEFLKGFRNAPTGLQRRLYGGIDLVKMRTPSIAGSFAVWGATFSTVDCALVHYRQREDA 88 Query: 231 INSILAGGITGGVLAIRGGWSQVAGQAFVGAVLLGIIEGCG 353 NSIL+G TGG+LA R G +A A VG ++L +IEG G Sbjct: 89 WNSILSGAATGGILAARNGIRAMANSALVGCLVLAMIEGAG 129
>sp|Q9Z0V7|TI17B_MOUSE Mitochondrial import inner membrane translocase subunit Tim17 B Length = 172 Score = 110 bits (276), Expect = 1e-24 Identities = 52/110 (47%), Positives = 72/110 (65%) Frame = +3 Query: 51 LFNFVAGFKDAPSGLSKRLISAATRCKIRSPVLGGSFAMWGGTFSCVDCALIYGRKKEDP 230 +F + GF++AP G+ R + +IR+P +GGSFA+WGG FS +DC L+ R KEDP Sbjct: 30 VFQAIKGFRNAPVGIRHRFRGSVNAVRIRAPQIGGSFAVWGGLFSTIDCGLVRLRGKEDP 89 Query: 231 INSILAGGITGGVLAIRGGWSQVAGQAFVGAVLLGIIEGCGILFQRFSTQ 380 NSI +G +TG VLA R G + G A +G +LL +IEG GIL R++ Q Sbjct: 90 WNSISSGALTGAVLAARSGPLAMVGSAMMGGILLALIEGVGILLTRYTAQ 139
>sp|O35092|TI17A_RAT Mitochondrial import inner membrane translocase subunit Tim17 A (Inner membrane preprotein translocase Tim17a) Length = 171 Score = 110 bits (276), Expect = 1e-24 Identities = 52/109 (47%), Positives = 73/109 (66%) Frame = +3 Query: 51 LFNFVAGFKDAPSGLSKRLISAATRCKIRSPVLGGSFAMWGGTFSCVDCALIYGRKKEDP 230 +F GF+++P G++ RL + T K R+P LGGSFA+WGG FS +DC ++ R KEDP Sbjct: 30 IFQAFKGFRNSPVGVNHRLRGSLTAIKTRAPQLGGSFAVWGGLFSTIDCGMVQIRGKEDP 89 Query: 231 INSILAGGITGGVLAIRGGWSQVAGQAFVGAVLLGIIEGCGILFQRFST 377 NSI +G +TG +LA R G + G A +G +LL +IEG GIL RF++ Sbjct: 90 WNSITSGALTGAILAARNGPVAMVGSAAMGGILLALIEGAGILLTRFAS 138
>sp|P39515|TIM17_YEAST Mitochondrial import inner membrane translocase subunit TIM17 (Mitochondrial protein import protein 2) (Mitochondrial inner membrane protein MIM17) Length = 158 Score = 107 bits (268), Expect = 1e-23 Identities = 51/104 (49%), Positives = 71/104 (68%) Frame = +3 Query: 63 VAGFKDAPSGLSKRLISAATRCKIRSPVLGGSFAMWGGTFSCVDCALIYGRKKEDPINSI 242 + GF+++P G +R A + K R+PVLGG+F +WGG FS DCA+ RK+EDP N+I Sbjct: 35 IKGFRNSPLG--ERGSGAMSAIKARAPVLGGNFGVWGGLFSTFDCAVKAVRKREDPWNAI 92 Query: 243 LAGGITGGVLAIRGGWSQVAGQAFVGAVLLGIIEGCGILFQRFS 374 +AG TGG LA+RGGW + A LLG+IEG G++FQR++ Sbjct: 93 IAGFFTGGALAVRGGWRHTRNSSITCACLLGVIEGVGLMFQRYA 136
>sp|O44477|TIM17_CAEEL Probable mitochondrial import inner membrane translocase subunit Tim17 Length = 181 Score = 104 bits (260), Expect = 1e-22 Identities = 55/130 (42%), Positives = 82/130 (63%) Frame = +3 Query: 51 LFNFVAGFKDAPSGLSKRLISAATRCKIRSPVLGGSFAMWGGTFSCVDCALIYGRKKEDP 230 +F G+K+A G K+L+ ++RS + G FA WGG FS +DC L+ RKKEDP Sbjct: 30 IFQAFGGYKNAAKG--KKLVGMMREVRMRSTLTGVQFAAWGGMFSTIDCCLVAIRKKEDP 87 Query: 231 INSILAGGITGGVLAIRGGWSQVAGQAFVGAVLLGIIEGCGILFQRFSTQAIVEESMPDN 410 INSI++GG+TG +LAIR G +AG A +G+V+L +IEG G++ R+ A+++ + P Sbjct: 88 INSIVSGGLTGALLAIRSGPKVMAGSAILGSVILAMIEGVGLVTTRW-MGAMMDPTQPPP 146 Query: 411 NQTISHQSLG 440 +SLG Sbjct: 147 EALDDPRSLG 156
>sp|Q9VN97|TI17D_DROME Probable mitochondrial import inner membrane translocase subunit Tim17 4 Length = 224 Score = 103 bits (256), Expect = 3e-22 Identities = 46/101 (45%), Positives = 69/101 (68%) Frame = +3 Query: 51 LFNFVAGFKDAPSGLSKRLISAATRCKIRSPVLGGSFAMWGGTFSCVDCALIYGRKKEDP 230 LF ++ GF++APSGL + L ++R+P + GSFA+WG TFS VDC ++ R++ED Sbjct: 29 LFQYLKGFRNAPSGLRRGLHGGIESVRLRTPAIAGSFAIWGATFSTVDCVMVSYRQREDS 88 Query: 231 INSILAGGITGGVLAIRGGWSQVAGQAFVGAVLLGIIEGCG 353 N+I++G TGG+LA R G +A AFVG ++L ++EG G Sbjct: 89 WNAIVSGAATGGILAARNGIRAMANSAFVGCLVLAMLEGAG 129
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 56,008,838 Number of Sequences: 369166 Number of extensions: 1199005 Number of successful extensions: 3869 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 3600 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 3835 length of database: 68,354,980 effective HSP length: 102 effective length of database: 49,512,010 effective search space used: 3168768640 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)