Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_008_H05
(756 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q19673|TYR3_CAEEL Putative tyrosinase-like protein tyr-3... 120 3e-27
sp|Q20191|NAS13_CAEEL Zinc metalloproteinase nas-13 precurs... 67 7e-11
sp|Q9QXX0|JAG1_MOUSE Jagged-1 precursor (Jagged1) 66 1e-10
sp|P78504|JAG1_HUMAN Jagged-1 precursor (Jagged1) (hJ1) (CD... 66 1e-10
sp|Q63722|JAG1_RAT Jagged-1 precursor (Jagged1) 66 1e-10
sp|Q90Y54|JAG1B_BRARE Jagged-1b precursor (Jagged1b) (Jagged3) 64 3e-10
sp|P34269|TYR1_CAEEL Putative tyrosinase-like protein tyr-1... 60 6e-09
sp|Q6DI48|DLLA_BRARE Delta-like protein A precursor (DeltaA... 57 5e-08
sp|Q9Y219|JAG2_HUMAN Jagged-2 precursor (Jagged2) (HJ2) 56 1e-07
sp|P21783|NOTCH_XENLA Neurogenic locus notch protein homolo... 56 1e-07
>sp|Q19673|TYR3_CAEEL Putative tyrosinase-like protein tyr-3 precursor
Length = 683
Score = 120 bits (302), Expect = 3e-27
Identities = 64/193 (33%), Positives = 85/193 (44%), Gaps = 35/193 (18%)
Frame = +2
Query: 2 CTKWAREGLCKKNFNFMQKNCKFSCDACQDIGDGDNSNPNCLNSHESCDTWADRGECASN 181
C W+ +G C+KN +M CK SC C N N C + H +C W+ GEC N
Sbjct: 469 CGPWSAKGECQKNPVYMNVWCKASCRQCTP---NYNINEECSDRHTNCAMWSRSGECNKN 525
Query: 182 PGYMLVSCKKACNVCGKENK-----------------------------------CADYR 256
P +M +C+ +C CG+ C +
Sbjct: 526 PLWMSENCRSSCQKCGRSRAATCGGGGGADSISNPTTMPPATNNGQQNTPCDSPMCYNED 585
Query: 257 KRCPIMAKYGLCESDPRFMLQNCKESCGVCDGSSKNRPCVDANQDCAGWAASHECETNPS 436
+ CPI A+ G C S+P +M CK SCGVC + PC D + DCA WA EC N
Sbjct: 586 QCCPIWAQRGQCRSNPGYMTCQCKVSCGVCRPNYVYGPCADYHYDCAAWARRGECLKN-K 644
Query: 437 WMLYNCKKSCNHC 475
WM NC++SCN C
Sbjct: 645 WMPENCRRSCNTC 657
Score = 115 bits (289), Expect = 1e-25
Identities = 64/212 (30%), Positives = 88/212 (41%), Gaps = 36/212 (16%)
Frame = +2
Query: 119 NCLNSHESCDTWADRGECASNPGYMLVSCKKACNVC----GKENKCADYRKRCPIMAKYG 286
+C N +E C W+ +GEC NP YM V CK +C C +C+D C + ++ G
Sbjct: 461 SCFNENECCGPWSAKGECQKNPVYMNVWCKASCRQCTPNYNINEECSDRHTNCAMWSRSG 520
Query: 287 LCESDPRFMLQNCKESCGVC---------------------------DGSSKNRP----- 370
C +P +M +NC+ SC C + +N P
Sbjct: 521 ECNKNPLWMSENCRSSCQKCGRSRAATCGGGGGADSISNPTTMPPATNNGQQNTPCDSPM 580
Query: 371 CVDANQDCAGWAASHECETNPSWMLYNCKKSCNHCRDARLESISDPNCKDLQIHCLYWAN 550
C + +Q C WA +C +NP +M CK SC CR + P C D C WA
Sbjct: 581 CYNEDQCCPIWAQRGQCRSNPGYMTCQCKVSCGVCRP---NYVYGP-CADYHYDCAAWAR 636
Query: 551 AGECQLNPGWAKQNCPFSCQHCGGCRDLIQNC 646
GEC N W +NC SC C + L C
Sbjct: 637 RGECLKNK-WMPENCRRSCNTCVNQQQLAARC 667
Score = 103 bits (258), Expect = 4e-22
Identities = 62/203 (30%), Positives = 89/203 (43%), Gaps = 35/203 (17%)
Frame = +2
Query: 224 CGKENKCADYRKRCPIMAKYGLCESDPRFMLQNCKESCGVCDGSSK-NRPCVDANQDCAG 400
C EN+C C + G C+ +P +M CK SC C + N C D + +CA
Sbjct: 462 CFNENEC------CGPWSAKGECQKNPVYMNVWCKASCRQCTPNYNINEECSDRHTNCAM 515
Query: 401 WAASHECETNPSWMLYNCKKSCNHCRDAR---------LESISDPN-------------- 511
W+ S EC NP WM NC+ SC C +R +SIS+P
Sbjct: 516 WSRSGECNKNPLWMSENCRSSCQKCGRSRAATCGGGGGADSISNPTTMPPATNNGQQNTP 575
Query: 512 -----CKDLQIHCLYWANAGECQLNPGWAKQNCPFSCQHC------GGCRDLIQNCQNFA 658
C + C WA G+C+ NPG+ C SC C G C D +C +A
Sbjct: 576 CDSPMCYNEDQCCPIWAQRGQCRSNPGYMTCQCKVSCGVCRPNYVYGPCADYHYDCAAWA 635
Query: 659 NQGYCKTNEVYMNQSCKKTCGFC 727
+G C N+ +M ++C+++C C
Sbjct: 636 RRGECLKNK-WMPENCRRSCNTC 657
>sp|Q20191|NAS13_CAEEL Zinc metalloproteinase nas-13 precursor (Nematode astacin 13)
Length = 527
Score = 66.6 bits (161), Expect = 7e-11
Identities = 36/84 (42%), Positives = 41/84 (48%), Gaps = 5/84 (5%)
Frame = +2
Query: 239 KCADYRKRCPIMAKYGLCES--DPRFMLQNCKESCGVCDGSSKNRP-CVDANQDCAGWAA 409
KC D RK C +A+ G CES RFM +NC SCG C K + C DA C WA
Sbjct: 444 KCEDRRKDCEFLARAGHCESRFSIRFMTENCANSCGKCIAEEKRKEVCEDARTWCERWAN 503
Query: 410 SHECETN--PSWMLYNCKKSCNHC 475
S C +M C KSCN C
Sbjct: 504 SGMCNQTVFKDYMRQKCAKSCNFC 527
Score = 49.3 bits (116), Expect = 1e-05
Identities = 27/83 (32%), Positives = 38/83 (45%), Gaps = 11/83 (13%)
Frame = +2
Query: 512 CKDLQIHCLYWANAGECQ--LNPGWAKQNCPFSCQHCGG-------CRDLIQNCQNFANQ 664
C+D + C + A AG C+ + + +NC SC C C D C+ +AN
Sbjct: 445 CEDRRKDCEFLARAGHCESRFSIRFMTENCANSCGKCIAEEKRKEVCEDARTWCERWANS 504
Query: 665 GYCKTN--EVYMNQSCKKTCGFC 727
G C + YM Q C K+C FC
Sbjct: 505 GMCNQTVFKDYMRQKCAKSCNFC 527
Score = 47.4 bits (111), Expect = 4e-05
Identities = 28/86 (32%), Positives = 38/86 (44%), Gaps = 4/86 (4%)
Frame = +2
Query: 371 CVDANQDCAGWAASHECETNPS--WMLYNCKKSCNHCRDARLESISDPNCKDLQIHCLYW 544
C D +DC A + CE+ S +M NC SC C E C+D + C W
Sbjct: 445 CEDRRKDCEFLARAGHCESRFSIRFMTENCANSCGKCI---AEEKRKEVCEDARTWCERW 501
Query: 545 ANAGECQ--LNPGWAKQNCPFSCQHC 616
AN+G C + + +Q C SC C
Sbjct: 502 ANSGMCNQTVFKDYMRQKCAKSCNFC 527
Score = 46.2 bits (108), Expect = 9e-05
Identities = 27/79 (34%), Positives = 37/79 (46%), Gaps = 4/79 (5%)
Frame = +2
Query: 2 CTKWAREGLCKKNFN--FMQKNCKFSCDACQDIGDGDNSNPNCLNSHESCDTWADRGECA 175
C AR G C+ F+ FM +NC SC C I + + C ++ C+ WA+ G C
Sbjct: 452 CEFLARAGHCESRFSIRFMTENCANSCGKC--IAE-EKRKEVCEDARTWCERWANSGMCN 508
Query: 176 SN--PGYMLVSCKKACNVC 226
YM C K+CN C
Sbjct: 509 QTVFKDYMRQKCAKSCNFC 527
Score = 42.0 bits (97), Expect = 0.002
Identities = 25/83 (30%), Positives = 34/83 (40%), Gaps = 8/83 (9%)
Frame = +2
Query: 122 CLNSHESCDTWADRGECASNPG--YMLVSCKKACNVCGKENK----CADYRKRCPIMAKY 283
C + + C+ A G C S +M +C +C C E K C D R C A
Sbjct: 445 CEDRRKDCEFLARAGHCESRFSIRFMTENCANSCGKCIAEEKRKEVCEDARTWCERWANS 504
Query: 284 GLCESD--PRFMLQNCKESCGVC 346
G+C +M Q C +SC C
Sbjct: 505 GMCNQTVFKDYMRQKCAKSCNFC 527
Score = 31.2 bits (69), Expect = 3.1
Identities = 12/39 (30%), Positives = 23/39 (58%), Gaps = 2/39 (5%)
Frame = +2
Query: 617 GGCRDLIQNCQNFANQGYCKT--NEVYMNQSCKKTCGFC 727
G C D ++C+ A G+C++ + +M ++C +CG C
Sbjct: 443 GKCEDRRKDCEFLARAGHCESRFSIRFMTENCANSCGKC 481
>sp|Q9QXX0|JAG1_MOUSE Jagged-1 precursor (Jagged1)
Length = 1218
Score = 65.9 bits (159), Expect = 1e-10
Identities = 67/296 (22%), Positives = 107/296 (36%), Gaps = 54/296 (18%)
Frame = +2
Query: 5 TKWAREGLCKKNFNFM--QKNCKFSCDACQDIGDGDN--------SNPNCLNSHESC--D 148
T W + LC K+ N+ + C + C + G S PNC + +C D
Sbjct: 286 TNWGGQ-LCDKDLNYCGTHQPC-LNRGTCSNTGPDKYQCSCPEGYSGPNCEIAEHACLSD 343
Query: 149 TWADRG---------ECASNPGYMLVSCKKACNVCGKENKCADYRKRCPIMAKYGLCESD 301
+RG EC +PG+ +C + C N + C + C
Sbjct: 344 PCHNRGSCKETSSGFECECSPGWTGPTCSTNIDDCSPNN--CSHGGTCQDLVNGFKCVCP 401
Query: 302 PRFMLQNCKESCGVCDGSSKNRPCVDANQDCAGWAASHECETNPSWMLYNCKKSCNHCRD 481
P++ + C+ C+ +PCV+A + C AS+ C+ P WM NC + N C
Sbjct: 402 PQWTGKTCQLDANECEA----KPCVNA-RSCKNLIASYYCDCLPGWMGQNCDININDCLG 456
Query: 482 ARLESISDPNCKDLQI-------------------------------HCLYWANAGECQL 568
+ +D +C+DL HC N +C
Sbjct: 457 ---QCQNDASCRDLVNGYRCICPPGYAGDHCERDIDECASNPCLNGGHCQNEINRFQCLC 513
Query: 569 NPGWAKQNCPFSCQHC--GGCRDLIQNCQNFANQGYCKTNEVYMNQSCKKTCGFCR 730
G++ C +C C++ Q C N A+ +CK E Y ++C CR
Sbjct: 514 PTGFSGNLCQLDIDYCEPNPCQNGAQ-CYNRASDYFCKCPEDYEGKNCSHLKDHCR 568
Score = 40.4 bits (93), Expect = 0.005
Identities = 50/244 (20%), Positives = 81/244 (33%), Gaps = 9/244 (3%)
Frame = +2
Query: 2 CTKWAREGLCKKNFNFMQKNCKFSCDACQDIGDGDNSNPNCLNSHESCDTWADRGECASN 181
C A + CK ++ KNC D C+ +SC +
Sbjct: 540 CYNRASDYFCKCPEDYEGKNCSHLKDHCRT---------TTCEVIDSCTVAMASNDTPEG 590
Query: 182 PGYMLVSCKKACNVCGKENKCADYRKRCPIMAKYGLCESDPRFMLQNCKESCGVCDGSSK 361
Y+ + NVCG KC K+ C+ + F C E+ C+ +
Sbjct: 591 VRYI------SSNVCGPHGKCKSQSG-----GKF-TCDCNKGFTGTYCHENINDCESN-- 636
Query: 362 NRPCVDANQDCAGWAASHECETNPSWMLYNCKKSCNHCRDARLESISDPNCKDLQIHCLY 541
PC + C S++C + W +C+ + N C ++ C+DL
Sbjct: 637 --PCKNGGT-CIDGVNSYKCICSDGWEGAHCENNINDC--SQNPCHYGGTCRDL------ 685
Query: 542 WANAGECQLNPGWAKQNC--------PFSCQHCGGCRDLIQNCQNFANQGYCKTN-EVYM 694
N C GW + C +C + G C D + + G+ T +
Sbjct: 686 -VNDFYCDCKNGWKGKTCHSRDSQCDEATCNNGGTCYDEVDTFKCMCPGGWEGTTCNIAR 744
Query: 695 NQSC 706
N SC
Sbjct: 745 NSSC 748
Score = 33.1 bits (74), Expect = 0.83
Identities = 33/160 (20%), Positives = 55/160 (34%), Gaps = 9/160 (5%)
Frame = +2
Query: 47 FMQKNCKFSCDACQDIGDGDNSNPNCLNSHESCDTWADRGECASNPGYMLVSCKKACNVC 226
+M +NC + + C D S + +N + C PGY C++ + C
Sbjct: 442 WMGQNCDININDCLGQCQNDASCRDLVNGYR----------CICPPGYAGDHCERDIDEC 491
Query: 227 GK---------ENKCADYRKRCPIMAKYGLCESDPRFMLQNCKESCGVCDGSSKNRPCVD 379
+N+ ++ CP LC+ D + N PC +
Sbjct: 492 ASNPCLNGGHCQNEINRFQCLCPTGFSGNLCQLDIDYCEPN---------------PCQN 536
Query: 380 ANQDCAGWAASHECETNPSWMLYNCKKSCNHCRDARLESI 499
Q C A+ + C+ + NC +HCR E I
Sbjct: 537 GAQ-CYNRASDYFCKCPEDYEGKNCSHLKDHCRTTTCEVI 575
>sp|P78504|JAG1_HUMAN Jagged-1 precursor (Jagged1) (hJ1) (CD339 antigen)
Length = 1218
Score = 65.9 bits (159), Expect = 1e-10
Identities = 67/296 (22%), Positives = 107/296 (36%), Gaps = 54/296 (18%)
Frame = +2
Query: 5 TKWAREGLCKKNFNFM--QKNCKFSCDACQDIGDGDN--------SNPNCLNSHESC--D 148
T W + LC K+ N+ + C + C + G S PNC + +C D
Sbjct: 286 TNWGGQ-LCDKDLNYCGTHQPC-LNGGTCSNTGPDKYQCSCPEGYSGPNCEIAEHACLSD 343
Query: 149 TWADRG---------ECASNPGYMLVSCKKACNVCGKENKCADYRKRCPIMAKYGLCESD 301
+RG EC +PG+ +C + C N + C + C
Sbjct: 344 PCHNRGSCKETSLGFECECSPGWTGPTCSTNIDDCSPNN--CSHGGTCQDLVNGFKCVCP 401
Query: 302 PRFMLQNCKESCGVCDGSSKNRPCVDANQDCAGWAASHECETNPSWMLYNCKKSCNHCRD 481
P++ + C+ C+ +PCV+A + C AS+ C+ P WM NC + N C
Sbjct: 402 PQWTGKTCQLDANECEA----KPCVNA-KSCKNLIASYYCDCLPGWMGQNCDININDCLG 456
Query: 482 ARLESISDPNCKDLQI-------------------------------HCLYWANAGECQL 568
+ +D +C+DL HC N +C
Sbjct: 457 ---QCQNDASCRDLVNGYRCICPPGYAGDHCERDIDECASNPCLNGGHCQNEINRFQCLC 513
Query: 569 NPGWAKQNCPFSCQHC--GGCRDLIQNCQNFANQGYCKTNEVYMNQSCKKTCGFCR 730
G++ C +C C++ Q C N A+ +CK E Y ++C CR
Sbjct: 514 PTGFSGNLCQLDIDYCEPNPCQNGAQ-CYNRASDYFCKCPEDYEGKNCSHLKDHCR 568
Score = 33.1 bits (74), Expect = 0.83
Identities = 53/268 (19%), Positives = 92/268 (34%), Gaps = 40/268 (14%)
Frame = +2
Query: 47 FMQKNCKFSCDACQDIGDGDNSNPNCLNSHESCDTWADRGECASNPGYMLVSCKKACNVC 226
+M +NC + + C D S + +N + C PGY C++ + C
Sbjct: 442 WMGQNCDININDCLGQCQNDASCRDLVNGYR----------CICPPGYAGDHCERDIDEC 491
Query: 227 GK---------ENKCADYRKRCPIMAKYGLCESDPRFMLQNCKESCGVCDGSSKNRPCVD 379
+N+ ++ CP LC+ D + N PC +
Sbjct: 492 ASNPCLNGGHCQNEINRFQCLCPTGFSGNLCQLDIDYCEPN---------------PCQN 536
Query: 380 ANQDCAGWAASHECETNPSWMLYNCKKSCNHCRDARLESI--------SDPNCKDLQI-- 529
Q C A+ + C+ + NC +HCR E I S+ + ++
Sbjct: 537 GAQ-CYNRASDYFCKCPEDYEGKNCSHLKDHCRTTPCEVIDSCTVAMASNDTPEGVRYIS 595
Query: 530 ------HCLYWANAG---ECQLNPGWAKQNCPFS--------CQHCGGCRDLIQNCQNFA 658
H + +G C N G+ C + C++ G C D + + +
Sbjct: 596 SNVCGPHGKCKSQSGGKFTCDCNKGFTGTYCHENINDCESNPCRNGGTCIDGVNSYKCIC 655
Query: 659 NQG----YCKTNEVYMNQSCKKTCGFCR 730
+ G YC+TN +Q+ G CR
Sbjct: 656 SDGWEGAYCETNINDCSQNPCHNGGTCR 683
>sp|Q63722|JAG1_RAT Jagged-1 precursor (Jagged1)
Length = 1219
Score = 65.9 bits (159), Expect = 1e-10
Identities = 67/296 (22%), Positives = 107/296 (36%), Gaps = 54/296 (18%)
Frame = +2
Query: 5 TKWAREGLCKKNFNFM--QKNCKFSCDACQDIGDGDN--------SNPNCLNSHESC--D 148
T W + LC K+ N+ + C + C + G S PNC + +C D
Sbjct: 286 TNWGGQ-LCDKDLNYCGTHQPC-LNRGTCSNTGPDKYQCSCPEGYSGPNCEIAEHACLSD 343
Query: 149 TWADRG---------ECASNPGYMLVSCKKACNVCGKENKCADYRKRCPIMAKYGLCESD 301
+RG EC +PG+ +C + C N + C + C
Sbjct: 344 PCHNRGSCKETSSGFECECSPGWTGPTCSTNIDDCSPNN--CSHGGTCQDLVNGFKCVCP 401
Query: 302 PRFMLQNCKESCGVCDGSSKNRPCVDANQDCAGWAASHECETNPSWMLYNCKKSCNHCRD 481
P++ + C+ C+ +PCV+A + C AS+ C+ P WM NC + N C
Sbjct: 402 PQWTGKTCQLDANECEA----KPCVNA-RSCKNLIASYYCDCLPGWMGQNCDININDCLG 456
Query: 482 ARLESISDPNCKDLQI-------------------------------HCLYWANAGECQL 568
+ +D +C+DL HC N +C
Sbjct: 457 ---QCQNDASCRDLVNGYRCICPPGYAGDHCERDIDECASNPCLNGGHCQNEINRFQCLC 513
Query: 569 NPGWAKQNCPFSCQHC--GGCRDLIQNCQNFANQGYCKTNEVYMNQSCKKTCGFCR 730
G++ C +C C++ Q C N A+ +CK E Y ++C CR
Sbjct: 514 PTGFSGNLCQLDIDYCEPNPCQNGAQ-CYNRASDYFCKCPEDYEGKNCSHLKDHCR 568
Score = 43.5 bits (101), Expect = 6e-04
Identities = 59/270 (21%), Positives = 92/270 (34%), Gaps = 42/270 (15%)
Frame = +2
Query: 23 GLCKKNFNFMQKNCK--FSCDACQDIGDGDNSNPNCLNSHESCDTWAD------------ 160
G C+ N Q C FS + CQ D NP C N + + +D
Sbjct: 500 GHCQNEINRFQCLCPTGFSGNLCQLDIDYCEPNP-CQNGAQCYNRASDYFCKCPEDYEGK 558
Query: 161 -----RGECASNPGYMLVSCKKAC--------------NVCGKENKCADYRKRCPIMAKY 283
+ C + P ++ SC A NVCG KC + K+
Sbjct: 559 NCSHLKDHCRTTPCEVIDSCTVAMASNDTPEGVRYISSNVCGPHGKC-----KSESGGKF 613
Query: 284 GLCESDPRFMLQNCKESCGVCDGSSKNRPCVDANQDCAGWAASHECETNPSWMLYNCKKS 463
C+ + F C E+ C+G+ PC + C S++C + W +C+ +
Sbjct: 614 -TCDCNKGFTGTYCHENINDCEGN----PCTNGGT-CIDGVNSYKCICSDGWEGAHCENN 667
Query: 464 CNHCRDARLESISDPNCKDLQIHCLYWANAGECQLNPGWAKQNC--------PFSCQHCG 619
N C ++ C+DL N C GW + C +C + G
Sbjct: 668 INDC--SQNPCHYGGTCRDL-------VNDFYCDCKNGWKGKTCHSRDSQCDEATCNNGG 718
Query: 620 GCRDLIQNCQNFANQGYCKTN-EVYMNQSC 706
C D + + G+ T + N SC
Sbjct: 719 TCYDEVDTFKCMCPGGWEGTTCNIARNSSC 748
Score = 32.7 bits (73), Expect = 1.1
Identities = 33/160 (20%), Positives = 55/160 (34%), Gaps = 9/160 (5%)
Frame = +2
Query: 47 FMQKNCKFSCDACQDIGDGDNSNPNCLNSHESCDTWADRGECASNPGYMLVSCKKACNVC 226
+M +NC + + C D S + +N + C PGY C++ + C
Sbjct: 442 WMGQNCDININDCLGQCQNDASCRDLVNGYR----------CICPPGYAGDHCERDIDEC 491
Query: 227 GK---------ENKCADYRKRCPIMAKYGLCESDPRFMLQNCKESCGVCDGSSKNRPCVD 379
+N+ ++ CP LC+ D + N PC +
Sbjct: 492 ASNPCLNGGHCQNEINRFQCLCPTGFSGNLCQLDIDYCEPN---------------PCQN 536
Query: 380 ANQDCAGWAASHECETNPSWMLYNCKKSCNHCRDARLESI 499
Q C A+ + C+ + NC +HCR E I
Sbjct: 537 GAQ-CYNRASDYFCKCPEDYEGKNCSHLKDHCRTTPCEVI 575
>sp|Q90Y54|JAG1B_BRARE Jagged-1b precursor (Jagged1b) (Jagged3)
Length = 1213
Score = 64.3 bits (155), Expect = 3e-10
Identities = 55/241 (22%), Positives = 87/241 (36%), Gaps = 38/241 (15%)
Frame = +2
Query: 122 CLNSHESCDTWADRGECASNPGYMLVSCKKACNVCGKENKCAD----------YRKRC-- 265
CLN +T D+ +C+ GY V+C++A + C N CA+ Y C
Sbjct: 303 CLNGGTCSNTGPDKYQCSCEDGYSGVNCERAEHAC-LSNPCANGGTCKETSQGYECHCAI 361
Query: 266 ---------------PIMAKYG----------LCESDPRFMLQNCKESCGVCDGSSKNRP 370
P K+G C P + + C+ C+ ++P
Sbjct: 362 GWSGTSCEINVDDCTPNQCKHGGTCQDLVNGFKCACPPHWTGKTCQIDANECE----DKP 417
Query: 371 CVDANQDCAGWAASHECETNPSWMLYNCKKSCNHCRDARLESISDPNCKDLQIHCLYWAN 550
CV+A + C ++ CE P W NC + N C+ + ++ CKDL N
Sbjct: 418 CVNA-KSCHNLIGAYFCECLPGWSGQNCDININDCKG---QCLNGGTCKDL-------VN 466
Query: 551 AGECQLNPGWAKQNCPFSCQHCGGCRDLI-QNCQNFANQGYCKTNEVYMNQSCKKTCGFC 727
C PG+ + C C L CQ+ N C + Q C+ +C
Sbjct: 467 GYRCLCPPGYTGEQCEKDVDECASSPCLNGGRCQDEVNGFQCLCPAGFSGQLCQLDIDYC 526
Query: 728 R 730
+
Sbjct: 527 K 527
Score = 38.1 bits (87), Expect = 0.026
Identities = 52/202 (25%), Positives = 77/202 (38%), Gaps = 4/202 (1%)
Frame = +2
Query: 23 GLCKKNFNFMQKNCKFSCDACQDIGDGDNSNPN-CLNSHESCD--TWADRGECASNPGYM 193
G C N + CK + + ++ NP+ C NS D W R ECA PG+
Sbjct: 754 GTCVVNGDSFNCVCKEGWEGSTCTENTNDCNPHPCYNSGTCVDGENWY-RCECA--PGFA 810
Query: 194 LVSCKKACNVCGKENKCADYRKRCPIMAKYGLCESDPRFMLQNCKESCGVCDGSSKNRPC 373
C+ N C + + CA + C C P + +C+E G RPC
Sbjct: 811 GPDCRININEC-QSSPCA-FGSTCVDEINGYRCLCPPGRIGPDCQEVVG--------RPC 860
Query: 374 VDANQDCAGWAASHECETNPSWMLYNCKKSCNHCRDARLESISDPNCKDLQIHC-LYWAN 550
+ Q A A W ++ CN C+ C++ +IHC + W
Sbjct: 861 IANGQVTADGA---------KW-----EEDCNICQ-----------CQNGRIHCTMMWCG 895
Query: 551 AGECQLNPGWAKQNCPFSCQHC 616
C++ G A+ CP S Q C
Sbjct: 896 PKSCRI--GKARGGCPAS-QSC 914
Score = 36.2 bits (82), Expect = 0.098
Identities = 55/261 (21%), Positives = 92/261 (35%), Gaps = 26/261 (9%)
Frame = +2
Query: 23 GLCKKNFNFMQKNCK--FSCDACQDIGDGDNSNPNCLNSHESCDTWADRGECASNPGYML 196
G CK N + C ++ + C+ D S+P CLN C + +C G+
Sbjct: 459 GTCKDLVNGYRCLCPPGYTGEQCEKDVDECASSP-CLNGGR-CQDEVNGFQCLCPAGFSG 516
Query: 197 VSCKKACNVCGKENKCADYRKRCPIMAKYGLCESDPRFMLQNCKE--------SCGVCDG 352
C+ + C K N C + +C +A C+ + +NC SC V D
Sbjct: 517 QLCQLDIDYC-KPNPCQN-GAQCFNLASDYFCKCPDDYEGKNCSHLKDHCRTTSCQVIDS 574
Query: 353 -----SSKNRP----------CVDANQDCAGWAASHECETNPSWMLYNCKKSCNHCRDAR 487
+S + P C + + CE + C ++ N C
Sbjct: 575 CTVAVASNSTPEGVRYISSNVCGPHGRCRSQAGGQFTCECQEGFRGTYCHENINDCE--- 631
Query: 488 LESISDPNCKDLQIHCLYWANAGECQLNPGWAKQNCPFSCQHCGGCRDLIQN-CQNFANQ 664
S+P C++ C+ N +C GW +C + C L + CQ+ N
Sbjct: 632 ----SNP-CRNGGT-CIDKVNVYQCICADGWEGVHCEINIDDCSLNPCLNKGACQDLVND 685
Query: 665 GYCKTNEVYMNQSCKKTCGFC 727
YC+ + ++C C
Sbjct: 686 FYCECRNGWKGKTCHSRDSQC 706
Score = 34.3 bits (77), Expect = 0.37
Identities = 57/275 (20%), Positives = 89/275 (32%), Gaps = 33/275 (12%)
Frame = +2
Query: 2 CTKWAREGLCKKNFNFMQKNCKFSCDACQDIGDGDNSNPNCLNSHESCDTWADRGECASN 181
C A + CK ++ KNC D C+ +C +SC
Sbjct: 537 CFNLASDYFCKCPDDYEGKNCSHLKDHCR--------TTSC-QVIDSCTVAVASNSTPEG 587
Query: 182 PGYMLVSCKKACNVCGKENKCADYRKRCPIMAKYGLCESDPRFMLQNCKESCGVCDGS-- 355
Y+ + NVCG +C R ++ CE F C E+ C+ +
Sbjct: 588 VRYI------SSNVCGPHGRC-----RSQAGGQF-TCECQEGFRGTYCHENINDCESNPC 635
Query: 356 SKNRPCVDA----NQDCA-GWAASH------ECETNPSWMLYNCKKSCN----HCRD--- 481
C+D CA GW H +C NP C+ N CR+
Sbjct: 636 RNGGTCIDKVNVYQCICADGWEGVHCEINIDDCSLNPCLNKGACQDLVNDFYCECRNGWK 695
Query: 482 ARLESISDPNCKDLQIH----CLYWANAGECQLNPGWAKQNC---------PFSCQHCGG 622
+ D C + + C + +C+ +PGW C P C++ G
Sbjct: 696 GKTCHSRDSQCDEATCNNGGTCHDEGDTFKCRCSPGWEGATCNIAKNSSCLPNPCENGGT 755
Query: 623 CRDLIQNCQNFANQGYCKTNEVYMNQSCKKTCGFC 727
C + N +F C E + +C + C
Sbjct: 756 C---VVNGDSF----NCVCKEGWEGSTCTENTNDC 783
Score = 32.3 bits (72), Expect = 1.4
Identities = 25/119 (21%), Positives = 45/119 (37%)
Frame = +2
Query: 128 NSHESCDTWADRGECASNPGYMLVSCKKACNVCGKENKCADYRKRCPIMAKYGLCESDPR 307
N+ +C D +C +PG+ +C A N N C + C + C
Sbjct: 712 NNGGTCHDEGDTFKCRCSPGWEGATCNIAKNSSCLPNPC-ENGGTCVVNGDSFNCVCKEG 770
Query: 308 FMLQNCKESCGVCDGSSKNRPCVDANQDCAGWAASHECETNPSWMLYNCKKSCNHCRDA 484
+ C E+ C+ PC ++ C + CE P + +C+ + N C+ +
Sbjct: 771 WEGSTCTENTNDCN----PHPCYNSG-TCVDGENWYRCECAPGFAGPDCRININECQSS 824
>sp|P34269|TYR1_CAEEL Putative tyrosinase-like protein tyr-1 precursor
Length = 601
Score = 60.1 bits (144), Expect = 6e-09
Identities = 23/81 (28%), Positives = 40/81 (49%)
Frame = +2
Query: 233 ENKCADYRKRCPIMAKYGLCESDPRFMLQNCKESCGVCDGSSKNRPCVDANQDCAGWAAS 412
++ C + C ++ C ++ +M + C++SCG+C + NR C D + CA W
Sbjct: 477 QSNCYNEDPCCNQWSRQNECRTNTVYMNRYCRKSCGLCQSNDNNRGCHDRHISCAYWRGQ 536
Query: 413 HECETNPSWMLYNCKKSCNHC 475
+ C WM NC+ +C C
Sbjct: 537 NFCTRRRQWMAENCQATCGWC 557
Score = 58.9 bits (141), Expect = 1e-08
Identities = 29/98 (29%), Positives = 43/98 (43%)
Frame = +2
Query: 371 CVDANQDCAGWAASHECETNPSWMLYNCKKSCNHCRDARLESISDPNCKDLQIHCLYWAN 550
C + + C W+ +EC TN +M C+KSC C+ + ++ C D I C YW
Sbjct: 480 CYNEDPCCNQWSRQNECRTNTVYMNRYCRKSCGLCQ----SNDNNRGCHDRHISCAYWRG 535
Query: 551 AGECQLNPGWAKQNCPFSCQHCGGCRDLIQNCQNFANQ 664
C W +NC +C C + Q C + A Q
Sbjct: 536 QNFCTRRRQWMAENCQATCGWCN--MNEAQLCASVARQ 571
Score = 57.0 bits (136), Expect = 5e-08
Identities = 24/80 (30%), Positives = 38/80 (47%), Gaps = 3/80 (3%)
Frame = +2
Query: 119 NCLNSHESCDTWADRGECASNPGYMLVSCKKACNVCGKENK---CADYRKRCPIMAKYGL 289
NC N C+ W+ + EC +N YM C+K+C +C + C D C
Sbjct: 479 NCYNEDPCCNQWSRQNECRTNTVYMNRYCRKSCGLCQSNDNNRGCHDRHISCAYWRGQNF 538
Query: 290 CESDPRFMLQNCKESCGVCD 349
C ++M +NC+ +CG C+
Sbjct: 539 CTRRRQWMAENCQATCGWCN 558
Score = 56.2 bits (134), Expect = 9e-08
Identities = 29/105 (27%), Positives = 46/105 (43%), Gaps = 5/105 (4%)
Frame = +2
Query: 2 CTKWAREGLCKKNFNFMQKNCKFSCDACQDIGDGDNSNPNCLNSHESCDTWADRGECASN 181
C +W+R+ C+ N +M + C+ SC CQ +++N C + H SC W + C
Sbjct: 487 CNQWSRQNECRTNTVYMNRYCRKSCGLCQ----SNDNNRGCHDRHISCAYWRGQNFCTRR 542
Query: 182 PGYMLVSCKKACNVCGKEN-----KCADYRKRCPIMAKYGLCESD 301
+M +C+ C C A +R AK+ L E D
Sbjct: 543 RQWMAENCQATCGWCNMNEAQLCASVARQSRRVRRNAKFWLTEPD 587
Score = 50.4 bits (119), Expect = 5e-06
Identities = 23/79 (29%), Positives = 36/79 (45%), Gaps = 6/79 (7%)
Frame = +2
Query: 509 NCKDLQIHCLYWANAGECQLNPGWAKQNCPFSCQHCG------GCRDLIQNCQNFANQGY 670
NC + C W+ EC+ N + + C SC C GC D +C + Q +
Sbjct: 479 NCYNEDPCCNQWSRQNECRTNTVYMNRYCRKSCGLCQSNDNNRGCHDRHISCAYWRGQNF 538
Query: 671 CKTNEVYMNQSCKKTCGFC 727
C +M ++C+ TCG+C
Sbjct: 539 CTRRRQWMAENCQATCGWC 557
Score = 42.4 bits (98), Expect = 0.001
Identities = 14/29 (48%), Positives = 21/29 (72%)
Frame = +2
Query: 644 CQNFANQGYCKTNEVYMNQSCKKTCGFCR 730
C ++ Q C+TN VYMN+ C+K+CG C+
Sbjct: 487 CNQWSRQNECRTNTVYMNRYCRKSCGLCQ 515
>sp|Q6DI48|DLLA_BRARE Delta-like protein A precursor (DeltaA protein)
Length = 772
Score = 57.0 bits (136), Expect = 5e-08
Identities = 54/224 (24%), Positives = 81/224 (36%), Gaps = 9/224 (4%)
Frame = +2
Query: 86 QDIGDGDNSNPNCLNSHESCDTWADRGECASNPGYMLVSCKKACNVCGKENKCADYRKRC 265
QD+ + P CLN +T C+ PG+ SC+ N C N C + C
Sbjct: 289 QDLNYCTHHKP-CLNGATCSNTGQGSYTCSCRPGFSGASCEIEVNEC-TGNPCRN-GGSC 345
Query: 266 PIMAKYGLCESDPRFMLQNCKESCGVC-DGSSKNRPCVDANQDCAGWAASHECETNPSWM 442
M C P F +NC+ S C DG PC + + + C+ +
Sbjct: 346 TDMENTYSCTCPPGFYGKNCELSAMTCADG-----PCFNGGRCADNPDGGYFCQCPTGYA 400
Query: 443 LYNCKKSCNHCRDARLESISDPNCKDLQIHCLYWANAGECQLNPGWAKQNCP-------- 598
+NC+K +HC S C + C+ N+ CQ G+ NC
Sbjct: 401 GFNCEKKIDHC--------SSSPCSN-GARCVDLVNSYLCQCPDGFTGMNCDRAGDECSM 451
Query: 599 FSCQHCGGCRDLIQNCQNFANQGYCKTNEVYMNQSCKKTCGFCR 730
+ CQ+ G CQ A+ C Y ++C C+
Sbjct: 452 YPCQNGG-------TCQEGASGYMCTCPPGYTGRNCSSPVSRCQ 488
Score = 42.0 bits (97), Expect = 0.002
Identities = 37/159 (23%), Positives = 53/159 (33%)
Frame = +2
Query: 2 CTKWAREGLCKKNFNFMQKNCKFSCDACQDIGDGDNSNPNCLNSHESCDTWADRGECASN 181
CT C F KNC+ S C D C N D C
Sbjct: 345 CTDMENTYSCTCPPGFYGKNCELSAMTCAD--------GPCFNGGRCADNPDGGYFCQCP 396
Query: 182 PGYMLVSCKKACNVCGKENKCADYRKRCPIMAKYGLCESDPRFMLQNCKESCGVCDGSSK 361
GY +C+K + C + C++ RC + LC+ F NC + C
Sbjct: 397 TGYAGFNCEKKIDHC-SSSPCSN-GARCVDLVNSYLCQCPDGFTGMNCDRAGDEC----S 450
Query: 362 NRPCVDANQDCAGWAASHECETNPSWMLYNCKKSCNHCR 478
PC + C A+ + C P + NC + C+
Sbjct: 451 MYPCQNGG-TCQEGASGYMCTCPPGYTGRNCSSPVSRCQ 488
>sp|Q9Y219|JAG2_HUMAN Jagged-2 precursor (Jagged2) (HJ2)
Length = 1238
Score = 55.8 bits (133), Expect = 1e-07
Identities = 63/276 (22%), Positives = 89/276 (32%), Gaps = 55/276 (19%)
Frame = +2
Query: 8 KWAREGLCKKNFNFMQKNCKFS-------------CDACQDIGDGDNSNPNCLNSHESC- 145
K +E +CK+ N + C CD C P C+ H SC
Sbjct: 238 KECKEAVCKQGCNLLHGGCTVPGECRCSYGWQGRFCDECVPY-------PGCV--HGSCV 288
Query: 146 DTWADRGECASNPGYMLVSCKKACNVCGKENKCAD-----------YRKRCPI------- 271
+ W + C +N G +L C K N CG + C + YR CP
Sbjct: 289 EPW--QCNCETNWGGLL--CDKDLNYCGSHHPCTNGGTCINAEPDQYRCTCPDGYSGRNC 344
Query: 272 -----------MAKYGLCESDPRFMLQNCKE-----SCGVCDGSSKNRPCVDANQDCAGW 403
A G C P +C +C + + PC A C
Sbjct: 345 EKAEHACTSNPCANGGSCHEVPSGFECHCPSGWSGPTCALDIDECASNPCA-AGGTCVDQ 403
Query: 404 AASHECETNPSWMLYNCKKSCNHCRDARLESISDPNCKDLQIHCLYWANAGECQLNPGWA 583
EC W+ C+ N C ++ +CK+L C PGW
Sbjct: 404 VDGFECICPEQWVGATCQLDANECEGK--PCLNAFSCKNL-------IGGYYCDCIPGWK 454
Query: 584 KQNCPFS-------CQHCGGCRDLIQNCQNFANQGY 670
NC + CQH G C+DL+ Q +G+
Sbjct: 455 GINCHINVNDCRGQCQHGGTCKDLVNGYQCVCPRGF 490
Score = 35.4 bits (80), Expect = 0.17
Identities = 53/228 (23%), Positives = 75/228 (32%), Gaps = 16/228 (7%)
Frame = +2
Query: 95 GDGDNSNPN-CL----NSHESCDTWADRGECASNPGYMLVSCKKA---CNV--CGKENKC 244
G+ ++NPN CL +S C + CA + G+ +C C+ C C
Sbjct: 668 GELCDTNPNDCLPDPCHSRGRCYDLVNDFYCACDDGWKGKTCHSREFQCDAYTCSNGGTC 727
Query: 245 AD----YRKRCPIMAKYGLCESDPRFMLQNCKESCGVCDGSS-KNRPCVDANQDCAGWAA 409
D +R CP K +C V SS PCV+ C G A
Sbjct: 728 YDSGDTFRCACPPGWK---------------GSTCAVAKNSSCLPNPCVNGGT-CVGSGA 771
Query: 410 SHECETNPSWMLYNCKKSCNHCRDARLESISDPNCKDLQIHCLYWANAGECQLNPGWAKQ 589
S C W C + N C C + I C+ N C+ PG+A
Sbjct: 772 SFSCICRDGWEGRTCTHNTNDCNPL--------PCYNGGI-CVDGVNWFRCECAPGFAGP 822
Query: 590 NCPFSCQHCGGCRDLI-QNCQNFANQGYCKTNEVYMNQSCKKTCGFCR 730
+C + C C + N C C++ GF R
Sbjct: 823 DCRINIDECQSSPCAYGATCVDEINGYRCSCPPGRAGPRCQEVIGFGR 870
>sp|P21783|NOTCH_XENLA Neurogenic locus notch protein homolog precursor (XOTCH protein)
Length = 2524
Score = 55.8 bits (133), Expect = 1e-07
Identities = 57/242 (23%), Positives = 91/242 (37%), Gaps = 7/242 (2%)
Frame = +2
Query: 23 GLCKKNFNFMQKNCK----FSCDACQDIGDGDNSNPNCLNSHESCDTWADRGECASNPGY 190
G C+ + + C+ ++ D+CQ D SNP C N + C + + C PG+
Sbjct: 115 GTCELLNSVTEYKCRCPPGWTGDSCQQ-ADPCASNP-CANGGK-CLPFEIQYICKCPPGF 171
Query: 191 MLVSCKKACNVCGKENKCADYRKRCPIMAKYGLCESDPRFMLQNCKESCGVCDGSSKNRP 370
+CK+ N C +N C + + Y C RF +NC E C+ S P
Sbjct: 172 HGATCKQDINECS-QNPCKNGGQCINEFGSYR-CTCQNRFTGRNCDEPYVPCNPS----P 225
Query: 371 CVDANQDCAGWAASHECETNPSWMLYNCKKSCNHCRDARLESISDPNCKDLQIHCLYWAN 550
C++ S++C P + NC+++ + C NC++ C+ N
Sbjct: 226 CLNGGTCRQTDDTSYDCTCLPGFSGQNCEENIDDC--------PSNNCRNGGT-CVDGVN 276
Query: 551 AGECQLNPGWAKQNCPFSCQHCGGCRDLIQN---CQNFANQGYCKTNEVYMNQSCKKTCG 721
CQ P W Q C C + QN C N C + + C +
Sbjct: 277 TYNCQCPPDWTGQYCTEDVDECQLMPNACQNGGTCHNTYGGYNCVCVNGWTGEDCSENID 336
Query: 722 FC 727
C
Sbjct: 337 DC 338
Score = 45.4 bits (106), Expect = 2e-04
Identities = 52/240 (21%), Positives = 85/240 (35%), Gaps = 4/240 (1%)
Frame = +2
Query: 23 GLCKKNFNFMQKNCK--FSCDACQDIGDGDNSNPNCLNSHESCDTWADRGECASNPGYML 196
G CK N C + C + NSNP C+ H +C + +C G+
Sbjct: 690 GTCKDQINGFTCVCPDGYHDHMCLSEVNECNSNP-CI--HGACHDGVNGYKCDCEAGWSG 746
Query: 197 VSCKKACNVCGKENKCADYRKRCPIMAKYGLCESDPRFMLQNCKESCGVCDGSSKNRPCV 376
+C N C + N C + C M +C F NC+ + C + PC+
Sbjct: 747 SNCDINNNEC-ESNPCMN-GGTCKDMTGAYICTCKAGFSGPNCQTNINECSSN----PCL 800
Query: 377 DANQDCAGWAASHECETNPSWMLYNCKKSCNHCRDARLESISDPNCKDLQIHCLYWANAG 556
+ + C A ++C + C+ C + ++ CK+ + +
Sbjct: 801 N-HGTCIDDVAGYKCNCMLPYTGAICEAVLAPCAGSPCKN--GGRCKESEDFETF----- 852
Query: 557 ECQLNPGWAKQNCPFSCQHCGG--CRDLIQNCQNFANQGYCKTNEVYMNQSCKKTCGFCR 730
C+ PGW Q C C CR+ CQN C Y ++C+ C+
Sbjct: 853 SCECPPGWQGQTCEIDMNECVNRPCRN-GATCQNTNGSYKCNCKPGYTGRNCEMDIDDCQ 911
Score = 43.1 bits (100), Expect = 8e-04
Identities = 53/224 (23%), Positives = 78/224 (34%), Gaps = 3/224 (1%)
Frame = +2
Query: 29 CKKNFNFMQKNCKFSCDACQDIGDGDNSNPNCLNSHESCDTWADRGECASNPGYMLVSCK 208
C + +NC+ D CQ PN ++ SC + C G+ C+
Sbjct: 892 CNCKPGYTGRNCEMDIDDCQ---------PNPCHNGGSCSDGINMFFCNCPAGFRGPKCE 942
Query: 209 KACNVCGKENKCADYRKRCPIMAKYGLCESDPRFMLQNCKESCGVCDGSSKNRPCVDANQ 388
+ N C N C + C C P F +C+ + C SS C +
Sbjct: 943 EDINECA-SNPCKN-GANCTDCVNSYTCTCQPGFSGIHCESNTPDCTESS----CFNGG- 995
Query: 389 DCAGWAASHECETNPSWMLYNCKKSCNHCRDARLESISDPNCKDLQIHCLYWANAGECQL 568
C + C+ P + C+ N C S P CL N G CQ
Sbjct: 996 TCIDGINTFTCQCPPGFTGSYCQHDINECD-------SKP--------CL---NGGTCQD 1037
Query: 569 NPGWAKQNCPFSCQHCGGCRDLIQNCQN--FANQGYC-KTNEVY 691
+ G K CP C++L++ C + N G C +TN Y
Sbjct: 1038 SYGTYKCTCPQGYTGL-NCQNLVRWCDSSPCKNGGKCWQTNNFY 1080
Score = 40.8 bits (94), Expect = 0.004
Identities = 63/248 (25%), Positives = 80/248 (32%), Gaps = 31/248 (12%)
Frame = +2
Query: 59 NCKFSCDACQDIGDGDNSNPNCLNSHESCDTWADRGECASNPGYMLVSCK---KAC--NV 223
NC+ D C SN L + C D EC PGY C C N
Sbjct: 636 NCETKIDDCA-------SN---LCDNGKCIDKIDGYECTCEPGYTGKLCNININECDSNP 685
Query: 224 CGKENKCAD----YRKRCPIMAKYGLCESDPRFMLQNCKES-C--GVCDGSSKNRPCVDA 382
C C D + CP +C S+ + C + C G C C
Sbjct: 686 CRNGGTCKDQINGFTCVCPDGYHDHMCLSE----VNECNSNPCIHGACHDGVNGYKC--- 738
Query: 383 NQDC-AGWAAS------HECETNPSWMLYNCKKSCNHCRDARLESISDPNCKDLQIHCLY 541
DC AGW+ S +ECE+NP CK S PNC+
Sbjct: 739 --DCEAGWSGSNCDINNNECESNPCMNGGTCKDMTGAYICTCKAGFSGPNCQ-------- 788
Query: 542 WANAGECQLNP---------GWAKQNCPFSCQHCGG-CRDLIQNCQN--FANQGYCKTNE 685
N EC NP A C + G C ++ C N G CK +E
Sbjct: 789 -TNINECSSNPCLNHGTCIDDVAGYKCNCMLPYTGAICEAVLAPCAGSPCKNGGRCKESE 847
Query: 686 VYMNQSCK 709
+ SC+
Sbjct: 848 DFETFSCE 855
Score = 39.7 bits (91), Expect = 0.009
Identities = 45/216 (20%), Positives = 72/216 (33%), Gaps = 13/216 (6%)
Frame = +2
Query: 23 GLCKK--NFNFMQKNCKFSCDACQDIGDGDNSNPNCLNSHESCDTWADRGECASNPGYML 196
G+C N +F + ++ C++ D +PN + +C + C GY
Sbjct: 1119 GMCVDTGNTHFCRCQAGYTGSYCEE--QVDECSPNPCQNGATCTDYLGGYSCECVAGYHG 1176
Query: 197 VSCKKACN-----VCGKENKCAD----YRKRCPIMAKYGLCESDPRFMLQNCKESCGVCD 349
V+C + N C C D Y+ CP + CE N + D
Sbjct: 1177 VNCSEEINECLSHPCQNGGTCIDLINTYKCSCPRGTQGVHCEI-------NVDDCTPFYD 1229
Query: 350 GSSKNRPCVDANQDCAGWAASHECETNPSWMLYNCKKSCNHCRDARLESISDPNCKDLQI 529
+ C + N C + C P ++ C+ N C +S NC L
Sbjct: 1230 SFTLEPKCFN-NGKCIDRVGGYNCICPPGFVGERCEGDVNECLSNPCDSRGTQNCIQL-- 1286
Query: 530 HCLYWANAGECQLNPGWAKQNCPFSCQHCGG--CRD 631
N C+ G+ + C C G CR+
Sbjct: 1287 -----VNDYRCECRQGFTGRRCESVVDGCKGMPCRN 1317
Score = 38.5 bits (88), Expect = 0.020
Identities = 59/240 (24%), Positives = 84/240 (35%), Gaps = 37/240 (15%)
Frame = +2
Query: 110 SNPNCLNSHESCDTWADRGE--CASNPGYM-------LVSCKKACNVCGKENKCAD---- 250
SNP N +CDT G+ C PGY + C N C +C +
Sbjct: 377 SNP--CNEGSNCDTNPVNGKAICTCPPGYTGPACNNDVDECSLGANPCEHGGRCTNTLGS 434
Query: 251 YRKRCPIMAKYGLCESDPRFMLQN-------CKESCG----VCDGSSKNRPCVDANQDCA 397
++ CP CE D L N C + G +C + C +CA
Sbjct: 435 FQCNCPQGYAGPRCEIDVNECLSNPCQNDSTCLDQIGEFQCICMPGYEGLYCETNIDECA 494
Query: 398 GWAASH--ECETNPSWMLYNCKK--SCNHCRDARLESISDPNCKDLQIHCLYWANAGECQ 565
H +C + +C S N C+ E S P CK+ CL N+ CQ
Sbjct: 495 SNPCLHNGKCIDKINEFRCDCPTGFSGNLCQHDFDECTSTP-CKN-GAKCLDGPNSYTCQ 552
Query: 566 LNPGWAKQNC--------PFSCQHCGGCRDLIQNCQNFANQGYC-KTNEVYMNQSCKKTC 718
G+ ++C P C H G C+D I GY + + +N+ K C
Sbjct: 553 CTEGFTGRHCEQDINECIPDPC-HYGTCKDGIATFTCLCRPGYTGRLCDNDINECLSKPC 611
Score = 37.4 bits (85), Expect = 0.044
Identities = 60/277 (21%), Positives = 93/277 (33%), Gaps = 45/277 (16%)
Frame = +2
Query: 23 GLCKKNFNFMQKNC--KFSCDACQDIGDGDNSNPNCLNSHESCDTWADRGECASNPGYML 196
G C F + C +F+ C + N +P CLN T +C PG+
Sbjct: 192 GQCINEFGSYRCTCQNRFTGRNCDEPYVPCNPSP-CLNGGTCRQTDDTSYDCTCLPGFSG 250
Query: 197 VSCKKACNVCGKEN-----KCAD----YRKRCPI--MAKYGLCESDPRFMLQNCKESCGV 343
+C++ + C N C D Y +CP +Y + D ++ N ++ G
Sbjct: 251 QNCEENIDDCPSNNCRNGGTCVDGVNTYNCQCPPDWTGQYCTEDVDECQLMPNACQNGGT 310
Query: 344 CDGSSKNRPCVDAN-----------QDCAGWAASHECETNPSWMLYNCKKSCNHCRDARL 490
C + CV N DCA A + + C+ C H R L
Sbjct: 311 CHNTYGGYNCVCVNGWTGEDCSENIDDCANAACHSGATCHDRVASFYCE--CPHGRTGLL 368
Query: 491 -----ESISDP-----NCKDLQIHCLYWANAGECQLNPGWAKQNCPFS----------CQ 610
IS+P NC ++ C PG+ C C+
Sbjct: 369 CHLDNACISNPCNEGSNCDTNPVN-----GKAICTCPPGYTGPACNNDVDECSLGANPCE 423
Query: 611 HCGGCRDLIQNCQNFANQGYCKTN-EVYMNQSCKKTC 718
H G C + + + Q QGY E+ +N+ C
Sbjct: 424 HGGRCTNTLGSFQCNCPQGYAGPRCEIDVNECLSNPC 460
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 93,956,899
Number of Sequences: 369166
Number of extensions: 2162016
Number of successful extensions: 7172
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5754
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6702
length of database: 68,354,980
effective HSP length: 108
effective length of database: 48,403,600
effective search space used: 6921714800
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)