Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_008_G07
(926 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q99MZ3|WBS14_MOUSE Williams-Beuren syndrome chromosome r... 88 4e-17
sp|Q9NP71|WBS14_HUMAN Williams-Beuren syndrome chromosome r... 86 1e-16
sp|Q9UH92|MLX_HUMAN MAx-like protein X (Max-like bHLHZip pr... 52 2e-06
sp|O08609|MLX_MOUSE MAx-like protein X (Max-like bHLHZip pr... 52 2e-06
sp|P41846|WBS14_CAEEL WBSCR14 protein homolog (Mlx interactor) 50 7e-06
sp|P29616|MYSC_CHICK Myosin heavy chain, cardiac muscle iso... 35 0.30
sp|Q9UTK5|ALM1_SCHPO Abnormal long morphology protein 1 (Sp8) 34 0.67
sp|Q01476|UBP2_YEAST Ubiquitin carboxyl-terminal hydrolase ... 33 1.5
sp|Q8NBJ4|GP73_HUMAN Golgi phosphoprotein 2 (Golgi membrane... 32 1.9
sp|Q09883|SPN6_SCHPO Septin homolog spn6 32 1.9
>sp|Q99MZ3|WBS14_MOUSE Williams-Beuren syndrome chromosome region 14 protein homolog (Mlx
interactor) (MLX-interacting protein-like)
Length = 864
Score = 87.8 bits (216), Expect = 4e-17
Identities = 45/124 (36%), Positives = 69/124 (55%)
Frame = +3
Query: 555 SSRDQNKISKAALLHKASEQIKRLRNEKYHIQSEIVSLQNEIDALQNRFSVFCSQLPATG 734
S++ K+SKA L K +E I L+ E+ +Q E L++EI+ L ++ QLPATG
Sbjct: 692 SAQPSLKVSKATTLQKTAEYILMLQQERAAMQEEAQQLRDEIEELNAAINLCQQQLPATG 751
Query: 735 VCLNSSKSSEGRKWFDEFVMKNSSTNWKFYIFCTMFESLFTSYNNSVSTLSMEDLAHNVA 914
V + + + R FD++V + NWKF++F + LF S+N VST S+ L
Sbjct: 752 VPITHQRFDQMRDMFDDYVRTRTLHNWKFWVFSILIRPLFESFNGMVSTASLHSLRQTSL 811
Query: 915 SWLE 926
+WLE
Sbjct: 812 AWLE 815
>sp|Q9NP71|WBS14_HUMAN Williams-Beuren syndrome chromosome region 14 protein (WS
basic-helix-loop-helix leucine zipper protein) (WS-bHLH)
(Mlx interactor) (MLX-interacting protein-like)
Length = 852
Score = 86.3 bits (212), Expect = 1e-16
Identities = 44/124 (35%), Positives = 69/124 (55%)
Frame = +3
Query: 555 SSRDQNKISKAALLHKASEQIKRLRNEKYHIQSEIVSLQNEIDALQNRFSVFCSQLPATG 734
S++ K+SKA L K +E I L+ E+ +Q E L++EI+ L ++ QLPATG
Sbjct: 680 SAQPSLKVSKATTLQKTAEYILMLQQERAGLQEEAQQLRDEIEELNAAINLCQQQLPATG 739
Query: 735 VCLNSSKSSEGRKWFDEFVMKNSSTNWKFYIFCTMFESLFTSYNNSVSTLSMEDLAHNVA 914
V + + + R FD++V + NWKF++F + LF S+N VST S+ L
Sbjct: 740 VPITHQRFDQMRDMFDDYVRTRTLHNWKFWVFSILIRPLFESFNGMVSTASVHTLRQTSL 799
Query: 915 SWLE 926
+WL+
Sbjct: 800 AWLD 803
>sp|Q9UH92|MLX_HUMAN MAx-like protein X (Max-like bHLHZip protein) (BigMax protein)
(Protein Mlx) (Transcription factor-like protein 4)
Length = 298
Score = 52.4 bits (124), Expect = 2e-06
Identities = 41/145 (28%), Positives = 73/145 (50%), Gaps = 6/145 (4%)
Frame = +3
Query: 510 NVVQQYLDELGTILTSSRDQN------KISKAALLHKASEQIKRLRNEKYHIQSEIVSLQ 671
+ +++ D+L TI+ + + Q+ K+SKA +L K + I+ L EK + E+ +L+
Sbjct: 143 DAIKRGYDDLQTIVPTCQQQDFSIGSQKLSKAIVLQKTIDYIQFLHKEKKKQEEEVSTLR 202
Query: 672 NEIDALQNRFSVFCSQLPATGVCLNSSKSSEGRKWFDEFVMKNSSTNWKFYIFCTMFESL 851
++ AL+ V Q+ V + EG + V KF +F + +SL
Sbjct: 203 KDVTALKI-MKVNYEQI----VKAHQDNPHEGEDQVSDQV--------KFNVFQGIMDSL 249
Query: 852 FTSYNNSVSTLSMEDLAHNVASWLE 926
F S+N S+S S ++L+ V SW+E
Sbjct: 250 FQSFNASISVASFQELSACVFSWIE 274
>sp|O08609|MLX_MOUSE MAx-like protein X (Max-like bHLHZip protein) (BigMax protein)
(Protein Mlx) (Transcription factor-like protein 4)
Length = 298
Score = 52.4 bits (124), Expect = 2e-06
Identities = 41/145 (28%), Positives = 73/145 (50%), Gaps = 6/145 (4%)
Frame = +3
Query: 510 NVVQQYLDELGTILTSSRDQN------KISKAALLHKASEQIKRLRNEKYHIQSEIVSLQ 671
+ +++ D+L TI+ + + Q+ K+SKA +L K + I+ L EK + E+ +L+
Sbjct: 143 DAIKRGYDDLQTIVPTCQQQDFSIGSQKLSKAIVLQKTIDYIQFLHKEKKKQEEEVSTLR 202
Query: 672 NEIDALQNRFSVFCSQLPATGVCLNSSKSSEGRKWFDEFVMKNSSTNWKFYIFCTMFESL 851
++ AL+ V Q+ V + EG + V KF +F + +SL
Sbjct: 203 KDVTALKI-MKVNYEQI----VKAHQDNPHEGEDQVSDQV--------KFNVFQGIMDSL 249
Query: 852 FTSYNNSVSTLSMEDLAHNVASWLE 926
F S+N S+S S ++L+ V SW+E
Sbjct: 250 FQSFNASISVASFQELSACVFSWIE 274
>sp|P41846|WBS14_CAEEL WBSCR14 protein homolog (Mlx interactor)
Length = 1009
Score = 50.4 bits (119), Expect = 7e-06
Identities = 30/126 (23%), Positives = 64/126 (50%), Gaps = 9/126 (7%)
Frame = +3
Query: 573 KISKAALLHKASEQIKRLRNEKYHIQSEIVSLQNEIDALQNRFSVFCSQLPATGVCLNSS 752
K + A +L K+++ I+RL+ EK+ +I + +I+ L + + S LP + +SS
Sbjct: 839 KPTNAVVLAKSADHIRRLQAEKWDKTQKIDEAKAKIEKLNQKITSLQSNLPQSSAPSSSS 898
Query: 753 K---SSEGRKWFDEFVMKNSSTNWKFYIFCTMFESLFTSYNNSVS------TLSMEDLAH 905
+ + +FD +V + + NW+F++ M + + + NS + + S ++A
Sbjct: 899 QVDSKTSLETFFDRYVKEGAKKNWRFWVMSQMLKPICVTQTNSFASSVAGDSSSRNEVAA 958
Query: 906 NVASWL 923
+ + WL
Sbjct: 959 SCSDWL 964
>sp|P29616|MYSC_CHICK Myosin heavy chain, cardiac muscle isoform
Length = 1102
Score = 35.0 bits (79), Expect = 0.30
Identities = 20/66 (30%), Positives = 38/66 (57%), Gaps = 7/66 (10%)
Frame = +3
Query: 507 NNVVQQYLDELGTILTSSRDQNKISKAALLHKASEQIKRLR-------NEKYHIQSEIVS 665
NN++Q LDEL +L + K+++ LL +A+E++ L N+K ++ +I
Sbjct: 844 NNLLQSELDELRALLDQTERARKLAEHELL-EATERVNLLHTQNTSLINQKKKLEGDISQ 902
Query: 666 LQNEID 683
+QNE++
Sbjct: 903 MQNEVE 908
>sp|Q9UTK5|ALM1_SCHPO Abnormal long morphology protein 1 (Sp8)
Length = 1727
Score = 33.9 bits (76), Expect = 0.67
Identities = 39/173 (22%), Positives = 76/173 (43%), Gaps = 21/173 (12%)
Frame = +3
Query: 414 IQPTSSAARYKKSKSPSLFNQSIKMKHN------LSANNV--VQQYLDELGTILTSSRDQ 569
+Q +A + K + SL+N + +N +S N++ +Q+ D + + L ++
Sbjct: 298 LQSEVAALQEKLTSQQSLYNNVTEELNNNKQQLLISENSLRELQEKYDSVVSELQVVKEN 357
Query: 570 NKISKAA---LLHKASEQIKRLRNEKYH----------IQSEIVSLQNEIDALQNRFSVF 710
S +A L ++++ ++N ++ +Q ++ SL+ ++D L N+FS F
Sbjct: 358 KNTSVSAGVGLFSPLAQKLSAVQNPEFSFTKVYSDNMKLQQKVSSLKLQLDRLTNKFSSF 417
Query: 711 CSQLPATGVCLNSSKSSEGRKWFDEFVMKNSSTNWKFYIFCTMFESLFTSYNN 869
C Q+ + +S E V N N+ + ESL TS NN
Sbjct: 418 CEQVKQRIPVVKQQRS--------EIVRNNIYMNF-------LSESLETSNNN 455
>sp|Q01476|UBP2_YEAST Ubiquitin carboxyl-terminal hydrolase 2 (Ubiquitin thiolesterase 2)
(Ubiquitin-specific processing protease 2)
(Deubiquitinating enzyme 2)
Length = 1272
Score = 32.7 bits (73), Expect = 1.5
Identities = 24/93 (25%), Positives = 45/93 (48%), Gaps = 6/93 (6%)
Frame = +3
Query: 564 DQNKISKAAL-LHKASEQIKRLRNEKYHIQSEIVSLQNEIDALQNRFSVFCSQLPATG-- 734
+ + I K L + A++ IK LRN +I +E++ L N+I++L+ + S G
Sbjct: 1135 ESDTIKKTPLKIEAANDVIKTLRNNVQNIDNELMKLYNDINSLEEKISHQFDDFKEYGYS 1194
Query: 735 ---VCLNSSKSSEGRKWFDEFVMKNSSTNWKFY 824
V ++ ++S G W +N + W+ Y
Sbjct: 1195 LFSVFIHRGEASYGHYWI-YIKDRNRNGIWRKY 1226
>sp|Q8NBJ4|GP73_HUMAN Golgi phosphoprotein 2 (Golgi membrane protein GP73)
Length = 401
Score = 32.3 bits (72), Expect = 1.9
Identities = 22/92 (23%), Positives = 39/92 (42%)
Frame = +3
Query: 480 IKMKHNLSANNVVQQYLDELGTILTSSRDQNKISKAALLHKASEQIKRLRNEKYHIQSEI 659
I+ HN +V + Y DE ++ N + L+ +Q+K L+ +Q ++
Sbjct: 84 IQSSHNFQLESVNKLYQDEKAVLVN-----NITTGERLIRVLQDQLKTLQRNYGRLQQDV 138
Query: 660 VSLQNEIDALQNRFSVFCSQLPATGVCLNSSK 755
+ Q L+ +FS SQ C+N K
Sbjct: 139 LQFQKNQTNLERKFSYDLSQ------CINQMK 164
>sp|Q09883|SPN6_SCHPO Septin homolog spn6
Length = 380
Score = 32.3 bits (72), Expect = 1.9
Identities = 29/117 (24%), Positives = 47/117 (40%), Gaps = 15/117 (12%)
Frame = +3
Query: 465 LFNQSIKMKHNLSANNVVQQYLDELGTILTSSRDQNKISKAALLHKASEQIKRLRNEKYH 644
L N+ + N + N+ ++Y R+Q K+ + E +RL NEK
Sbjct: 270 LINRHMLELINTTETNIYERY----------RREQLTNRKSGIPKLKKEHYERLNNEKRA 319
Query: 645 IQSEIVSLQNEI---------------DALQNRFSVFCSQLPATGVCLNSSKSSEGR 770
IQ +I + NE DAL + S + ++ A + S KS +GR
Sbjct: 320 IQQKITQMTNETESFFQAKEEKMIETRDALNSELSEYHERIRALETQIESLKSYKGR 376
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 107,167,455
Number of Sequences: 369166
Number of extensions: 2216934
Number of successful extensions: 5735
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5456
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5725
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 9510757740
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)