Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_008_F08
(843 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9UBX3|DIC_HUMAN Mitochondrial dicarboxylate carrier 257 2e-68
sp|Q9QZD8|DIC_MOUSE Mitochondrial dicarboxylate carrier 250 3e-66
sp|Q9CR62|M2OM_MOUSE Mitochondrial 2-oxoglutarate/malate ca... 160 3e-39
sp|Q02978|M2OM_HUMAN Mitochondrial 2-oxoglutarate/malate ca... 160 3e-39
sp|P22292|M2OM_BOVIN Mitochondrial 2-oxoglutarate/malate ca... 160 3e-39
sp|P97700|M2OM_RAT Mitochondrial 2-oxoglutarate/malate carr... 157 3e-38
sp|O97562|UCP2_PIG Mitochondrial uncoupling protein 2 (UCP 2) 142 1e-33
sp|P56499|UCP3_RAT Mitochondrial uncoupling protein 3 (UCP 3) 141 3e-33
sp|P56501|UCP3_MOUSE Mitochondrial uncoupling protein 3 (UC... 140 4e-33
sp|O77792|UCP3_BOVIN Mitochondrial uncoupling protein 3 (UC... 139 1e-32
>sp|Q9UBX3|DIC_HUMAN Mitochondrial dicarboxylate carrier
Length = 287
Score = 257 bits (657), Expect = 2e-68
Identities = 131/225 (58%), Positives = 164/225 (72%), Gaps = 4/225 (1%)
Frame = +1
Query: 1 ALYNGLSASLLRQLTYSMTRFGLYETYK----ASKKGATPFYEKAGVSMVSGFIGGIVGN 168
ALY+GLSASL RQ+TYS+TRF +YET + +G PF+EK + VSG GG VG
Sbjct: 59 ALYSGLSASLCRQMTYSLTRFAIYETVRDRVAKGSQGPLPFHEKVLLGSVSGLAGGFVGT 118
Query: 169 PADMVNVRMQNDMKVAKELRRNYKNAVDGMFRVAREEGVVVLFSGVSMTATRAAFMTFGQ 348
PAD+VNVRMQND+K+ + RRNY +A+DG++RVAREEG+ LFSG +M ++R A +T GQ
Sbjct: 119 PADLVNVRMQNDVKLPQGQRRNYAHALDGLYRVAREEGLRRLFSGATMASSRGALVTVGQ 178
Query: 349 LAFYDLFKQMMIQSGLFSDNIITHFTASTGAAGIATLMTQPFDVMKTRLMNAKPGTYSGL 528
L+ YD KQ+++ +G SDNI THF AS A G AT + QP DV+KTRLMN+K G Y G+
Sbjct: 179 LSCYDQAKQLVLSTGYLSDNIFTHFVASFIAGGCATFLCQPLDVLKTRLMNSK-GEYQGV 237
Query: 529 LECGADIMKTGPLGFFKGLVPAFIRLGPQTILTFVFLEQLRMNFG 663
C + K GPL F+KGLVPA IRL P T+LTFVFLEQLR NFG
Sbjct: 238 FHCAVETAKLGPLAFYKGLVPAGIRLIPHTVLTFVFLEQLRKNFG 282
>sp|Q9QZD8|DIC_MOUSE Mitochondrial dicarboxylate carrier
Length = 287
Score = 250 bits (639), Expect = 3e-66
Identities = 127/225 (56%), Positives = 159/225 (70%), Gaps = 4/225 (1%)
Frame = +1
Query: 1 ALYNGLSASLLRQLTYSMTRFGLYETYK----ASKKGATPFYEKAGVSMVSGFIGGIVGN 168
ALYNGLSASL RQ+TYS+TRF +YET + +G PFY K + +SG GG VG
Sbjct: 58 ALYNGLSASLCRQMTYSLTRFAIYETMRDYMTKDSQGPLPFYNKVLLGGISGLTGGFVGT 117
Query: 169 PADMVNVRMQNDMKVAKELRRNYKNAVDGMFRVAREEGVVVLFSGVSMTATRAAFMTFGQ 348
PAD+VNVRMQNDMK+ RRNY +A+DG++RVAREE + LFSG +M ++R A +T GQ
Sbjct: 118 PADLVNVRMQNDMKLPPSQRRNYSHALDGLYRVAREESLRKLFSGATMASSRGALVTVGQ 177
Query: 349 LAFYDLFKQMMIQSGLFSDNIITHFTASTGAAGIATLMTQPFDVMKTRLMNAKPGTYSGL 528
L+ YD KQ+++ +G SDNI THF +S A G AT + QP DV+KTRLMN+K G Y G+
Sbjct: 178 LSCYDQAKQLVLSTGYLSDNIFTHFVSSFIAGGCATFLCQPLDVLKTRLMNSK-GEYQGV 236
Query: 529 LECGADIMKTGPLGFFKGLVPAFIRLGPQTILTFVFLEQLRMNFG 663
C + K GP FFKGL PA IRL P T+LTF+FLEQLR +FG
Sbjct: 237 FHCAMETAKLGPQAFFKGLFPAGIRLIPHTVLTFMFLEQLRKHFG 281
>sp|Q9CR62|M2OM_MOUSE Mitochondrial 2-oxoglutarate/malate carrier protein (OGCP) (Solute
carrier family 25 member 11)
Length = 314
Score = 160 bits (406), Expect = 3e-39
Identities = 93/224 (41%), Positives = 125/224 (55%), Gaps = 9/224 (4%)
Frame = +1
Query: 4 LYNGLSASLLRQLTYSMTRFGLYETYKASKKGA--TP--FYEKAGVSMVSGFIGGIVGNP 171
+Y GLSA LLRQ TY+ TR G+Y GA TP F KA + M +G G VG P
Sbjct: 80 IYTGLSAGLLRQATYTTTRLGIYTVLFERLTGADGTPPGFLLKALIGMTAGATGAFVGTP 139
Query: 172 ADMVNVRMQNDMKVAKELRRNYKNAVDGMFRVAREEGVVVLFSGVSMTATRAAFMTFGQL 351
A++ +RM D ++ + RR YKN + + R+AREEGV L+ G T RA + QL
Sbjct: 140 AEVALIRMTADGRLPADQRRGYKNVFNALVRIAREEGVPTLWRGCIPTMARAVVVNAAQL 199
Query: 352 AFYDLFKQMMIQSGLFSDNIITHFTASTGAAGIATLMTQPFDVMKTRLMN-----AKPGT 516
A Y KQ ++ SG FSDNI+ HF AS + + T + P D++KTR+ N KP
Sbjct: 200 ASYSQSKQFLLDSGYFSDNILCHFCASMISGLVTTAASMPVDIVKTRIQNMRMIDGKPEY 259
Query: 517 YSGLLECGADIMKTGPLGFFKGLVPAFIRLGPQTILTFVFLEQL 648
+GL + G +KG P + RLGP T+LTF+FLEQ+
Sbjct: 260 KNGLDVLLKVVRYEGFFSLWKGFTPYYARLGPHTVLTFIFLEQM 303
Score = 33.9 bits (76), Expect = 0.58
Identities = 26/89 (29%), Positives = 42/89 (47%), Gaps = 8/89 (8%)
Frame = +1
Query: 136 VSGFIGGIVG-------NPADMVNVRMQNDMKVAKELRRNYKNAVDGMFRVAREEGVVVL 294
V GG+ G P D+V RMQ + AK R YK + + + + EG+ +
Sbjct: 23 VKFLFGGLAGMGATVFVQPLDLVKNRMQLSGEGAKT--REYKTSFHALTSILKTEGLKGI 80
Query: 295 FSGVSMTATRAAFMTFGQLAFYD-LFKQM 378
++G+S R A T +L Y LF+++
Sbjct: 81 YTGLSAGLLRQATYTTTRLGIYTVLFERL 109
>sp|Q02978|M2OM_HUMAN Mitochondrial 2-oxoglutarate/malate carrier protein (OGCP) (Solute
carrier family 25 member 11)
Length = 314
Score = 160 bits (406), Expect = 3e-39
Identities = 92/224 (41%), Positives = 124/224 (55%), Gaps = 9/224 (4%)
Frame = +1
Query: 4 LYNGLSASLLRQLTYSMTRFGLYETYKASKKGA--TP--FYEKAGVSMVSGFIGGIVGNP 171
+Y GLSA LLRQ TY+ TR G+Y GA TP F KA + M +G G VG P
Sbjct: 80 IYTGLSAGLLRQATYTTTRLGIYTVLFERLTGADGTPPGFLLKAVIGMTAGATGAFVGTP 139
Query: 172 ADMVNVRMQNDMKVAKELRRNYKNAVDGMFRVAREEGVVVLFSGVSMTATRAAFMTFGQL 351
A++ +RM D ++ + RR YKN + + R+ REEGV+ L+ G T RA + QL
Sbjct: 140 AEVALIRMTADGRLPADQRRGYKNVFNALIRITREEGVLTLWRGCIPTMARAVVVNAAQL 199
Query: 352 AFYDLFKQMMIQSGLFSDNIITHFTASTGAAGIATLMTQPFDVMKTRLMN-----AKPGT 516
A Y KQ ++ SG FSDNI+ HF AS + + T + P D+ KTR+ N KP
Sbjct: 200 ASYSQSKQFLLDSGYFSDNILCHFCASMISGLVTTAASMPVDIAKTRIQNMRMIDGKPEY 259
Query: 517 YSGLLECGADIMKTGPLGFFKGLVPAFIRLGPQTILTFVFLEQL 648
+GL + G +KG P + RLGP T+LTF+FLEQ+
Sbjct: 260 KNGLDVLFKVVRYEGFFSLWKGFTPYYARLGPHTVLTFIFLEQM 303
Score = 33.5 bits (75), Expect = 0.76
Identities = 26/89 (29%), Positives = 42/89 (47%), Gaps = 8/89 (8%)
Frame = +1
Query: 136 VSGFIGGIVG-------NPADMVNVRMQNDMKVAKELRRNYKNAVDGMFRVAREEGVVVL 294
V GG+ G P D+V RMQ + AK R YK + + + + EG+ +
Sbjct: 23 VKFLFGGLAGMGATVFVQPLDLVKNRMQLSGEGAKT--REYKTSFHALTSILKAEGLRGI 80
Query: 295 FSGVSMTATRAAFMTFGQLAFYD-LFKQM 378
++G+S R A T +L Y LF+++
Sbjct: 81 YTGLSAGLLRQATYTTTRLGIYTVLFERL 109
>sp|P22292|M2OM_BOVIN Mitochondrial 2-oxoglutarate/malate carrier protein (OGCP)
Length = 314
Score = 160 bits (406), Expect = 3e-39
Identities = 92/224 (41%), Positives = 125/224 (55%), Gaps = 9/224 (4%)
Frame = +1
Query: 4 LYNGLSASLLRQLTYSMTRFGLYETYKASKKGA--TP--FYEKAGVSMVSGFIGGIVGNP 171
+Y GLSA LLRQ TY+ TR G+Y GA TP F KA + M +G G VG P
Sbjct: 80 IYTGLSAGLLRQATYTTTRLGIYTVLFERLTGADGTPPGFLLKAVIGMTAGATGAFVGTP 139
Query: 172 ADMVNVRMQNDMKVAKELRRNYKNAVDGMFRVAREEGVVVLFSGVSMTATRAAFMTFGQL 351
A++ +RM D ++ + RR YKN + +FR+ +EEGV L+ G T RA + QL
Sbjct: 140 AEVALIRMTADGRLPVDQRRGYKNVFNALFRIVQEEGVPTLWRGCIPTMARAVVVNAAQL 199
Query: 352 AFYDLFKQMMIQSGLFSDNIITHFTASTGAAGIATLMTQPFDVMKTRLMN-----AKPGT 516
A Y KQ ++ SG FSDNI+ HF AS + + T + P D++KTR+ N KP
Sbjct: 200 ASYSQSKQFLLDSGYFSDNILCHFCASMISGLVTTAASMPVDIVKTRIQNMRMIDGKPEY 259
Query: 517 YSGLLECGADIMKTGPLGFFKGLVPAFIRLGPQTILTFVFLEQL 648
+GL + G +KG P + RLGP T+LTF+FLEQ+
Sbjct: 260 KNGLDVLVKVVRYEGFFSLWKGFTPYYARLGPHTVLTFIFLEQM 303
Score = 35.4 bits (80), Expect = 0.20
Identities = 27/89 (30%), Positives = 42/89 (47%), Gaps = 8/89 (8%)
Frame = +1
Query: 136 VSGFIGGIVG-------NPADMVNVRMQNDMKVAKELRRNYKNAVDGMFRVAREEGVVVL 294
V GG+ G P D+V RMQ + AK R YK + + + R EG+ +
Sbjct: 23 VKFLFGGLAGMGATVFVQPLDLVKNRMQLSGEGAKT--REYKTSFHALISILRAEGLRGI 80
Query: 295 FSGVSMTATRAAFMTFGQLAFYD-LFKQM 378
++G+S R A T +L Y LF+++
Sbjct: 81 YTGLSAGLLRQATYTTTRLGIYTVLFERL 109
>sp|P97700|M2OM_RAT Mitochondrial 2-oxoglutarate/malate carrier protein (OGCP) (Solute
carrier family 25 member 11)
Length = 314
Score = 157 bits (398), Expect = 3e-38
Identities = 92/224 (41%), Positives = 124/224 (55%), Gaps = 9/224 (4%)
Frame = +1
Query: 4 LYNGLSASLLRQLTYSMTRFGLYETYKASKKGA--TP--FYEKAGVSMVSGFIGGIVGNP 171
+Y GLSA LLRQ TY+ TR G+Y GA TP F KA + M +G G VG P
Sbjct: 80 IYTGLSAGLLRQATYTTTRLGIYTVLFERLTGADGTPPGFLLKALIGMTAGATGAFVGPP 139
Query: 172 ADMVNVRMQNDMKVAKELRRNYKNAVDGMFRVAREEGVVVLFSGVSMTATRAAFMTFGQL 351
A++ +RM D ++ + RR YKN + + R+AREEGV L+ G T RA + QL
Sbjct: 140 AEVALIRMTADGRLPADQRRGYKNVFNALIRIAREEGVPTLWRGCIPTMARAVVVNAAQL 199
Query: 352 AFYDLFKQMMIQSGLFSDNIITHFTASTGAAGIATLMTQPFDVMKTRLMN-----AKPGT 516
A Y KQ ++ SG FSDNI+ HF A + + T + P D++KTR+ N KP
Sbjct: 200 ASYSQSKQFLLDSGYFSDNILCHFCAIMISGLVTTAASMPVDIVKTRIQNMRMIDEKPEY 259
Query: 517 YSGLLECGADIMKTGPLGFFKGLVPAFIRLGPQTILTFVFLEQL 648
+GL + G +KG P + RLGP T+LTF+FLEQ+
Sbjct: 260 KNGLDVLLKVVRYEGFFSLWKGFTPYYARLGPHTVLTFIFLEQM 303
Score = 33.1 bits (74), Expect = 0.99
Identities = 26/89 (29%), Positives = 42/89 (47%), Gaps = 8/89 (8%)
Frame = +1
Query: 136 VSGFIGGIVG-------NPADMVNVRMQNDMKVAKELRRNYKNAVDGMFRVAREEGVVVL 294
V GG+ G P D+V RMQ + AK R YK + + + + EG+ +
Sbjct: 23 VKFLFGGLAGMGATVFVQPLDLVXNRMQLSGEGAKT--REYKTSFHALTSILKAEGLRGI 80
Query: 295 FSGVSMTATRAAFMTFGQLAFYD-LFKQM 378
++G+S R A T +L Y LF+++
Sbjct: 81 YTGLSAGLLRQATYTTTRLGIYTVLFERL 109
>sp|O97562|UCP2_PIG Mitochondrial uncoupling protein 2 (UCP 2)
Length = 309
Score = 142 bits (358), Expect = 1e-33
Identities = 83/225 (36%), Positives = 124/225 (55%), Gaps = 8/225 (3%)
Frame = +1
Query: 1 ALYNGLSASLLRQLTYSMTRFGLYETYKAS-KKGATPFYEKAGVSM------VSGFIGGI 159
+LYNGL A L RQ++++ R GLY++ K KG+ E AG+ +G +
Sbjct: 77 SLYNGLVAGLQRQMSFASVRIGLYDSVKHFYTKGS----EHAGIGSRLLAGSTTGALAVA 132
Query: 160 VGNPADMVNVRMQNDMKVAKELRRNYKNAVDGMFRVAREEGVVVLFSGVSMTATRAAFMT 339
V P D+V VR Q + R Y++ VD +AREEG+ L+ G S R A +
Sbjct: 133 VAQPTDVVKVRFQAQARAGGG--RRYRSTVDAYKTIAREEGLRGLWKGTSPNVARNAIVN 190
Query: 340 FGQLAFYDLFKQMMIQSGLFSDNIITHFTASTGAAGIATLMTQPFDVMKTRLMNAKPGTY 519
+L YDL K ++++ L +D++ HFT++ GA T++ P DV+KTR MN+ PG Y
Sbjct: 191 CAELVTYDLIKDTLLKADLMTDDLPCHFTSAFGAGFCTTVIASPVDVVKTRYMNSAPGQY 250
Query: 520 SGLLECGADIM-KTGPLGFFKGLVPAFIRLGPQTILTFVFLEQLR 651
S C ++ K GP F+KG P+F+RLG ++ FV EQL+
Sbjct: 251 SSAGHCALTMLQKEGPRAFYKGFTPSFLRLGSWNVVMFVTYEQLK 295
>sp|P56499|UCP3_RAT Mitochondrial uncoupling protein 3 (UCP 3)
Length = 308
Score = 141 bits (355), Expect = 3e-33
Identities = 77/220 (35%), Positives = 120/220 (54%), Gaps = 5/220 (2%)
Frame = +1
Query: 7 YNGLSASLLRQLTYSMTRFGLYETYKASKKGATPFYEKAGVSMVSGFIGGIVG----NPA 174
Y+GL A L RQ++++ R GLY++ K + + +++G G + P
Sbjct: 75 YSGLVAGLHRQMSFASIRIGLYDSVKQFYTPKGTDHSSVAIRILAGCTTGAMAVTCAQPT 134
Query: 175 DMVNVRMQNDMKVAKELRRNYKNAVDGMFRVAREEGVVVLFSGVSMTATRAAFMTFGQLA 354
D+V VR Q +++ R Y+ +D +AREEGV L+ G TR A + ++
Sbjct: 135 DVVKVRFQAMIRLGTGGERKYRGTMDAYRTIAREEGVRGLWKGTWPNITRNAIVNCAEMV 194
Query: 355 FYDLFKQMMIQSGLFSDNIITHFTASTGAAGIATLMTQPFDVMKTRLMNAKPGTYSGLLE 534
YD+ K+ ++ S LF+DN HF ++ GA AT++ P DV+KTR MNA PG Y L
Sbjct: 195 TYDIIKEKLLDSHLFTDNFPCHFVSAFGAGFCATVVASPVDVVKTRYMNAPPGRYRSPLH 254
Query: 535 CGAD-IMKTGPLGFFKGLVPAFIRLGPQTILTFVFLEQLR 651
C + + GP F+KG +P+F+RLG ++ FV EQL+
Sbjct: 255 CMLRMVAQEGPTAFYKGFMPSFLRLGSWNVMMFVTYEQLK 294
Score = 37.4 bits (85), Expect = 0.052
Identities = 36/152 (23%), Positives = 55/152 (36%), Gaps = 7/152 (4%)
Frame = +1
Query: 169 PADMVNVRMQNDMKVAKELRRNYKNAVDGMFRVAREEGVVVLFSGVSMTATRAAFMTFGQ 348
P D VR+Q + Y+ + + + R EG +SG+ R +
Sbjct: 33 PLDTAKVRLQIQGENPGVQSVQYRGVLGTILTMVRTEGPRSPYSGLVAGLHRQMSFASIR 92
Query: 349 LAFYDLFKQMMIQSGLFSDNIITHFTASTGAAGIATLMTQPFDVMKTRLM-NAKPGT--- 516
+ YD KQ G ++ A +A QP DV+K R + GT
Sbjct: 93 IGLYDSVKQFYTPKGTDHSSVAIRILAGCTTGAMAVTCAQPTDVVKVRFQAMIRLGTGGE 152
Query: 517 --YSGLLECGADIMK-TGPLGFFKGLVPAFIR 603
Y G ++ I + G G +KG P R
Sbjct: 153 RKYRGTMDAYRTIAREEGVRGLWKGTWPNITR 184
>sp|P56501|UCP3_MOUSE Mitochondrial uncoupling protein 3 (UCP 3)
Length = 308
Score = 140 bits (353), Expect = 4e-33
Identities = 80/222 (36%), Positives = 124/222 (55%), Gaps = 7/222 (3%)
Frame = +1
Query: 7 YNGLSASLLRQLTYSMTRFGLYETYKA--SKKGATPFYEKAGVSMVSGFIGGIVG----N 168
Y+GL A L RQ++++ R GLY++ K + KGA + + +++G G +
Sbjct: 75 YSGLVAGLHRQMSFASIRIGLYDSVKQFYTPKGAD--HSSVAIRILAGCTTGAMAVTCAQ 132
Query: 169 PADMVNVRMQNDMKVAKELRRNYKNAVDGMFRVAREEGVVVLFSGVSMTATRAAFMTFGQ 348
P D+V VR Q +++ R Y+ +D +AREEGV L+ G TR A + +
Sbjct: 133 PTDVVKVRFQAMIRLGTGGERKYRGTMDAYRTIAREEGVRGLWKGTWPNITRNAIVNCAE 192
Query: 349 LAFYDLFKQMMIQSGLFSDNIITHFTASTGAAGIATLMTQPFDVMKTRLMNAKPGTYSGL 528
+ YD+ K+ +++S LF+DN HF ++ GA AT++ P DV+KTR MNA G Y
Sbjct: 193 MVTYDIIKEKLLESHLFTDNFPCHFVSAFGAGFCATVVASPVDVVKTRYMNAPLGRYRSP 252
Query: 529 LECGAD-IMKTGPLGFFKGLVPAFIRLGPQTILTFVFLEQLR 651
L C + + GP F+KG VP+F+RLG ++ FV EQL+
Sbjct: 253 LHCMLKMVAQEGPTAFYKGFVPSFLRLGAWNVMMFVTYEQLK 294
Score = 37.7 bits (86), Expect = 0.040
Identities = 36/152 (23%), Positives = 55/152 (36%), Gaps = 7/152 (4%)
Frame = +1
Query: 169 PADMVNVRMQNDMKVAKELRRNYKNAVDGMFRVAREEGVVVLFSGVSMTATRAAFMTFGQ 348
P D VR+Q + Y+ + + + R EG +SG+ R +
Sbjct: 33 PLDTAKVRLQIQGENPGAQSVQYRGVLGTILTMVRTEGPRSPYSGLVAGLHRQMSFASIR 92
Query: 349 LAFYDLFKQMMIQSGLFSDNIITHFTASTGAAGIATLMTQPFDVMKTRLM-NAKPGT--- 516
+ YD KQ G ++ A +A QP DV+K R + GT
Sbjct: 93 IGLYDSVKQFYTPKGADHSSVAIRILAGCTTGAMAVTCAQPTDVVKVRFQAMIRLGTGGE 152
Query: 517 --YSGLLECGADIMK-TGPLGFFKGLVPAFIR 603
Y G ++ I + G G +KG P R
Sbjct: 153 RKYRGTMDAYRTIAREEGVRGLWKGTWPNITR 184
>sp|O77792|UCP3_BOVIN Mitochondrial uncoupling protein 3 (UCP 3)
Length = 311
Score = 139 bits (349), Expect = 1e-32
Identities = 76/222 (34%), Positives = 119/222 (53%), Gaps = 5/222 (2%)
Frame = +1
Query: 1 ALYNGLSASLLRQLTYSMTRFGLYETYKA--SKKGA--TPFYEKAGVSMVSGFIGGIVGN 168
+LY+GL A L RQ++++ R GLY++ K + KG+ + + +G +
Sbjct: 76 SLYSGLVAGLQRQMSFASIRIGLYDSVKQFYTPKGSDHSSIITRILAGCTTGAMAVTCAQ 135
Query: 169 PADMVNVRMQNDMKVAKELRRNYKNAVDGMFRVAREEGVVVLFSGVSMTATRAAFMTFGQ 348
P D+V +R Q M R Y +D +AREEGV L+ G+ TR A + G+
Sbjct: 136 PTDVVKIRFQASMHTGLGGNRKYSGTMDAYRTIAREEGVRGLWKGILPNITRNAIVNCGE 195
Query: 349 LAFYDLFKQMMIQSGLFSDNIITHFTASTGAAGIATLMTQPFDVMKTRLMNAKPGTYSGL 528
+ YD+ K+ ++ L +DN HF ++ GA ATL+ P DV+KTR MN+ PG Y
Sbjct: 196 MVTYDIIKEKLLDYHLLTDNFPCHFVSAFGAGFCATLVASPVDVVKTRYMNSPPGQYHSP 255
Query: 529 LECGAD-IMKTGPLGFFKGLVPAFIRLGPQTILTFVFLEQLR 651
+C + + GP F+KG P+F+RLG ++ FV EQ++
Sbjct: 256 FDCMLKMVTQEGPTAFYKGFTPSFLRLGSWNVVMFVTYEQMK 297
Score = 48.1 bits (113), Expect = 3e-05
Identities = 43/155 (27%), Positives = 64/155 (41%), Gaps = 10/155 (6%)
Frame = +1
Query: 169 PADMVNVRMQ--NDMKVAKELRR-NYKNAVDGMFRVAREEGVVVLFSGVSMTATRAAFMT 339
P D VR+Q + + A R Y+ + + + R EG L+SG+ R
Sbjct: 33 PLDTAKVRLQIQGENQAALAARSAQYRGVLGTILTMVRTEGPRSLYSGLVAGLQRQMSFA 92
Query: 340 FGQLAFYDLFKQMMIQSGLFSDNIITHFTASTGAAGIATLMTQPFDVMKTRL---MNAKP 510
++ YD KQ G +IIT A +A QP DV+K R M+
Sbjct: 93 SIRIGLYDSVKQFYTPKGSDHSSIITRILAGCTTGAMAVTCAQPTDVVKIRFQASMHTGL 152
Query: 511 G---TYSGLLECGADIMK-TGPLGFFKGLVPAFIR 603
G YSG ++ I + G G +KG++P R
Sbjct: 153 GGNRKYSGTMDAYRTIAREEGVRGLWKGILPNITR 187
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 92,741,656
Number of Sequences: 369166
Number of extensions: 1857504
Number of successful extensions: 5180
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4505
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4969
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 8245425915
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)