Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_008_F05
(541 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|O60830|TI17B_HUMAN Mitochondrial import inner membrane t... 128 8e-30
sp|Q99595|TI17A_HUMAN Mitochondrial import inner membrane t... 127 2e-29
sp|Q9VNA0|TI17A_DROME Probable mitochondrial import inner m... 126 4e-29
sp|Q9Z0V8|TI17A_MOUSE Mitochondrial import inner membrane t... 125 5e-29
sp|Q9Z0V7|TI17B_MOUSE Mitochondrial import inner membrane t... 125 9e-29
sp|O35092|TI17A_RAT Mitochondrial import inner membrane tra... 125 9e-29
sp|Q9VGA2|TI17C_DROME Probable mitochondrial import inner m... 119 4e-27
sp|P39515|TIM17_YEAST Mitochondrial import inner membrane t... 118 1e-26
sp|P59670|TIM17_NEUCR Mitochondrial import inner membrane t... 115 7e-26
sp|O44477|TIM17_CAEEL Probable mitochondrial import inner m... 114 1e-25
>sp|O60830|TI17B_HUMAN Mitochondrial import inner membrane translocase subunit Tim17 B
(JM3)
Length = 172
Score = 128 bits (322), Expect = 8e-30
Identities = 61/133 (45%), Positives = 82/133 (61%)
Frame = +2
Query: 26 DPCPWRIFSDXXXXXXXXXXXXXLFNFVAGFKDAPSGLSKRLISAATRCKIRSPVLGGSF 205
+PCPWRI D +F + GF++AP G+ RL +A +IR+P +GGSF
Sbjct: 7 EPCPWRIVDDCGGAFTMGVIGGGVFQAIKGFRNAPVGIRHRLRGSANAVRIRAPQIGGSF 66
Query: 206 AMWGGTFSCVDCALIYGRKKEDPINSILAGGITGGVLAIRGGWSQVAGQAFVGAVLLGII 385
A+WGG FS +DC L+ R KEDP NSI +G +TG VLA R G + G A +G +LL +I
Sbjct: 67 AVWGGLFSTIDCGLVRLRGKEDPWNSITSGALTGAVLAARSGPLAMVGSAMMGGILLALI 126
Query: 386 EGCGILFQRFSTQ 424
EG GIL R++ Q
Sbjct: 127 EGVGILLTRYTAQ 139
>sp|Q99595|TI17A_HUMAN Mitochondrial import inner membrane translocase subunit Tim17 A
(Inner membrane preprotein translocase Tim17a)
Length = 171
Score = 127 bits (319), Expect = 2e-29
Identities = 59/132 (44%), Positives = 83/132 (62%)
Frame = +2
Query: 26 DPCPWRIFSDXXXXXXXXXXXXXLFNFVAGFKDAPSGLSKRLISAATRCKIRSPVLGGSF 205
+PCPWRI D +F + GF+++P G++ RL + T K R+P LGGSF
Sbjct: 7 EPCPWRIVDDCGGAFTMGTIGGGIFQAIKGFRNSPVGVNHRLRGSLTAIKTRAPQLGGSF 66
Query: 206 AMWGGTFSCVDCALIYGRKKEDPINSILAGGITGGVLAIRGGWSQVAGQAFVGAVLLGII 385
A+WGG FS +DC+++ R KEDP NSI +G +TG +LA R G + G A +G +LL +I
Sbjct: 67 AVWGGLFSMIDCSMVQVRGKEDPWNSITSGALTGAILAARNGPVAMVGSAAMGGILLALI 126
Query: 386 EGCGILFQRFST 421
EG GIL RF++
Sbjct: 127 EGAGILLTRFAS 138
>sp|Q9VNA0|TI17A_DROME Probable mitochondrial import inner membrane translocase subunit
Tim17 1
Length = 179
Score = 126 bits (316), Expect = 4e-29
Identities = 62/155 (40%), Positives = 88/155 (56%)
Frame = +2
Query: 26 DPCPWRIFSDXXXXXXXXXXXXXLFNFVAGFKDAPSGLSKRLISAATRCKIRSPVLGGSF 205
+PCP+RI D F + GF++APSGL RL + RS ++GG+F
Sbjct: 7 EPCPFRIVEDCGGAFAMGALGGGAFQAIKGFRNAPSGLGYRLSGGLAAVRARSGLVGGNF 66
Query: 206 AMWGGTFSCVDCALIYGRKKEDPINSILAGGITGGVLAIRGGWSQVAGQAFVGAVLLGII 385
A+WG TFS +DC+L+Y RKKEDP N+I++G TGG+LA R G + + A VG LL +I
Sbjct: 67 AVWGATFSAIDCSLVYFRKKEDPWNAIISGATTGGILAARTGLTSMLSSALVGGALLALI 126
Query: 386 EGCGILFQRFSTQAIVEESMPDNNQTISHQSLGLQ 490
EG GI+ +S + + S + Q + L Q
Sbjct: 127 EGVGIVVSHYSADSYRQVSPVERQQRYKQELLRQQ 161
>sp|Q9Z0V8|TI17A_MOUSE Mitochondrial import inner membrane translocase subunit Tim17 A
(Inner membrane preprotein translocase Tim17a)
Length = 171
Score = 125 bits (315), Expect = 5e-29
Identities = 59/132 (44%), Positives = 82/132 (62%)
Frame = +2
Query: 26 DPCPWRIFSDXXXXXXXXXXXXXLFNFVAGFKDAPSGLSKRLISAATRCKIRSPVLGGSF 205
+PCPWRI D +F GF+++P G++ RL + T K R+P LGGSF
Sbjct: 7 EPCPWRIVDDCGGAFTMGTIGGGIFQAFKGFRNSPVGINHRLRGSLTAIKTRAPQLGGSF 66
Query: 206 AMWGGTFSCVDCALIYGRKKEDPINSILAGGITGGVLAIRGGWSQVAGQAFVGAVLLGII 385
A+WGG FS +DC+++ R KEDP NSI +G +TG +LA R G + G A +G +LL +I
Sbjct: 67 AVWGGLFSTIDCSMVQIRGKEDPWNSITSGALTGAILAARNGPVAMVGSAAMGGILLALI 126
Query: 386 EGCGILFQRFST 421
EG GIL RF++
Sbjct: 127 EGAGILLTRFAS 138
>sp|Q9Z0V7|TI17B_MOUSE Mitochondrial import inner membrane translocase subunit Tim17 B
Length = 172
Score = 125 bits (313), Expect = 9e-29
Identities = 59/133 (44%), Positives = 80/133 (60%)
Frame = +2
Query: 26 DPCPWRIFSDXXXXXXXXXXXXXLFNFVAGFKDAPSGLSKRLISAATRCKIRSPVLGGSF 205
+PCPWRI D +F + GF++AP G+ R + +IR+P +GGSF
Sbjct: 7 EPCPWRIVDDCGGAFTMGVIGGGVFQAIKGFRNAPVGIRHRFRGSVNAVRIRAPQIGGSF 66
Query: 206 AMWGGTFSCVDCALIYGRKKEDPINSILAGGITGGVLAIRGGWSQVAGQAFVGAVLLGII 385
A+WGG FS +DC L+ R KEDP NSI +G +TG VLA R G + G A +G +LL +I
Sbjct: 67 AVWGGLFSTIDCGLVRLRGKEDPWNSISSGALTGAVLAARSGPLAMVGSAMMGGILLALI 126
Query: 386 EGCGILFQRFSTQ 424
EG GIL R++ Q
Sbjct: 127 EGVGILLTRYTAQ 139
>sp|O35092|TI17A_RAT Mitochondrial import inner membrane translocase subunit Tim17 A
(Inner membrane preprotein translocase Tim17a)
Length = 171
Score = 125 bits (313), Expect = 9e-29
Identities = 59/132 (44%), Positives = 81/132 (61%)
Frame = +2
Query: 26 DPCPWRIFSDXXXXXXXXXXXXXLFNFVAGFKDAPSGLSKRLISAATRCKIRSPVLGGSF 205
+PCPWRI D +F GF+++P G++ RL + T K R+P LGGSF
Sbjct: 7 EPCPWRIVDDCGGAFTMGTIGGGIFQAFKGFRNSPVGVNHRLRGSLTAIKTRAPQLGGSF 66
Query: 206 AMWGGTFSCVDCALIYGRKKEDPINSILAGGITGGVLAIRGGWSQVAGQAFVGAVLLGII 385
A+WGG FS +DC ++ R KEDP NSI +G +TG +LA R G + G A +G +LL +I
Sbjct: 67 AVWGGLFSTIDCGMVQIRGKEDPWNSITSGALTGAILAARNGPVAMVGSAAMGGILLALI 126
Query: 386 EGCGILFQRFST 421
EG GIL RF++
Sbjct: 127 EGAGILLTRFAS 138
>sp|Q9VGA2|TI17C_DROME Probable mitochondrial import inner membrane translocase subunit
Tim17 3
Length = 222
Score = 119 bits (299), Expect = 4e-27
Identities = 58/129 (44%), Positives = 79/129 (61%)
Frame = +2
Query: 11 IRHEGDPCPWRIFSDXXXXXXXXXXXXXLFNFVAGFKDAPSGLSKRLISAATRCKIRSPV 190
+ + PCP RI D LF F+ GF++AP+GL +RL K+R+P
Sbjct: 1 MEYNRQPCPIRIVEDCGCAFMMGTIGGSLFEFLKGFRNAPTGLQRRLYGGIDLVKMRTPS 60
Query: 191 LGGSFAMWGGTFSCVDCALIYGRKKEDPINSILAGGITGGVLAIRGGWSQVAGQAFVGAV 370
+ GSFA+WG TFS VDCAL++ R++ED NSIL+G TGG+LA R G +A A VG +
Sbjct: 61 IAGSFAVWGATFSTVDCALVHYRQREDAWNSILSGAATGGILAARNGIRAMANSALVGCL 120
Query: 371 LLGIIEGCG 397
+L +IEG G
Sbjct: 121 VLAMIEGAG 129
>sp|P39515|TIM17_YEAST Mitochondrial import inner membrane translocase subunit TIM17
(Mitochondrial protein import protein 2) (Mitochondrial
inner membrane protein MIM17)
Length = 158
Score = 118 bits (295), Expect = 1e-26
Identities = 58/134 (43%), Positives = 82/134 (61%)
Frame = +2
Query: 17 HEGDPCPWRIFSDXXXXXXXXXXXXXLFNFVAGFKDAPSGLSKRLISAATRCKIRSPVLG 196
H DPCP I +D +++ + GF+++P G +R A + K R+PVLG
Sbjct: 5 HSRDPCPIVILNDFGGAFAMGAIGGVVWHGIKGFRNSPLG--ERGSGAMSAIKARAPVLG 62
Query: 197 GSFAMWGGTFSCVDCALIYGRKKEDPINSILAGGITGGVLAIRGGWSQVAGQAFVGAVLL 376
G+F +WGG FS DCA+ RK+EDP N+I+AG TGG LA+RGGW + A LL
Sbjct: 63 GNFGVWGGLFSTFDCAVKAVRKREDPWNAIIAGFFTGGALAVRGGWRHTRNSSITCACLL 122
Query: 377 GIIEGCGILFQRFS 418
G+IEG G++FQR++
Sbjct: 123 GVIEGVGLMFQRYA 136
>sp|P59670|TIM17_NEUCR Mitochondrial import inner membrane translocase subunit tim-17
Length = 155
Score = 115 bits (288), Expect = 7e-26
Identities = 66/153 (43%), Positives = 88/153 (57%), Gaps = 3/153 (1%)
Frame = +2
Query: 17 HEGDPCPWRIFSDXXXXXXXXXXXXXLFNFVAGFKDAPSGLSKRLISAATRCKIRSPVLG 196
H DPCPW I +D +++ + GF+++P G +R I A T K+R+P LG
Sbjct: 3 HTRDPCPWVILNDFGGAFAMGAIGGTIWHGIKGFRNSPYG--ERRIGAITAIKMRAPALG 60
Query: 197 GSFAMWGGTFSCVDCALIYGRK-KEDPINSILAGGITGGVLAIRGGWSQVAGQAFVGAVL 373
G+F +WGG FS DCA+ R KEDP NSILAG TGG LA+RGG+ A AVL
Sbjct: 61 GNFGVWGGLFSTFDCAIKGLRNHKEDPWNSILAGFFTGGALAVRGGYKAARNGAIGCAVL 120
Query: 374 LGIIEGCGILFQRFSTQAIVEE--SMPDNNQTI 466
L +IEG GI FQ+ A E + P +N+ +
Sbjct: 121 LAVIEGVGIGFQKMLAGATKLEAPAPPPSNEKV 153
>sp|O44477|TIM17_CAEEL Probable mitochondrial import inner membrane translocase subunit
Tim17
Length = 181
Score = 114 bits (286), Expect = 1e-25
Identities = 61/153 (39%), Positives = 90/153 (58%)
Frame = +2
Query: 26 DPCPWRIFSDXXXXXXXXXXXXXLFNFVAGFKDAPSGLSKRLISAATRCKIRSPVLGGSF 205
+PCP+RI D +F G+K+A G K+L+ ++RS + G F
Sbjct: 7 EPCPYRIGDDIGSAFAMGLVGGSIFQAFGGYKNAAKG--KKLVGMMREVRMRSTLTGVQF 64
Query: 206 AMWGGTFSCVDCALIYGRKKEDPINSILAGGITGGVLAIRGGWSQVAGQAFVGAVLLGII 385
A WGG FS +DC L+ RKKEDPINSI++GG+TG +LAIR G +AG A +G+V+L +I
Sbjct: 65 AAWGGMFSTIDCCLVAIRKKEDPINSIVSGGLTGALLAIRSGPKVMAGSAILGSVILAMI 124
Query: 386 EGCGILFQRFSTQAIVEESMPDNNQTISHQSLG 484
EG G++ R+ A+++ + P +SLG
Sbjct: 125 EGVGLVTTRW-MGAMMDPTQPPPEALDDPRSLG 156
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 61,317,957
Number of Sequences: 369166
Number of extensions: 1291249
Number of successful extensions: 4031
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3738
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3992
length of database: 68,354,980
effective HSP length: 104
effective length of database: 49,142,540
effective search space used: 3685690500
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)