Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_008_E17
(639 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P28812|Y3568_PSEAE Hypothetical protein PA3568 166 5e-41
sp|P59871|ACSA_MYCBO Acetyl-coenzyme A synthetase (Acetate-... 156 5e-38
sp|Q72LY9|ACSA_LEPIC Acetyl-coenzyme A synthetase (Acetate-... 154 2e-37
sp|Q8EYG2|ACSA_LEPIN Acetyl-coenzyme A synthetase (Acetate-... 154 2e-37
sp|O69635|ACSA_MYCTU Acetyl-coenzyme A synthetase (Acetate-... 153 3e-37
sp|Q8UBV5|ACSA_AGRT5 Acetyl-coenzyme A synthetase (Acetate-... 149 6e-36
sp|Q9RRL7|ACSA_DEIRA Acetyl-coenzyme A synthetase (Acetate-... 147 2e-35
sp|Q82EL5|ACSA_STRAW Acetyl-coenzyme A synthetase (Acetate-... 147 2e-35
sp|Q9KWA3|ACSA_AGRRH Acetyl-coenzyme A synthetase (Acetate-... 146 5e-35
sp|Q9X928|ACSA_STRCO Acetyl-coenzyme A synthetase (Acetate-... 145 1e-34
>sp|P28812|Y3568_PSEAE Hypothetical protein PA3568
Length = 628
Score = 166 bits (420), Expect = 5e-41
Identities = 79/178 (44%), Positives = 115/178 (64%)
Frame = +3
Query: 105 YQIEFKQSIENKEEFWRKAANEIIWKKPSTQILDTTELHAPKWFNGSELNICHNCVDRHV 284
Y + +SI FW + A + W + IL++ +WF LN + +DR +
Sbjct: 3 YLQQHARSIAEPAAFWAEQARSLAWYQAPANILESLPDGTHRWFADGRLNSAYLALDRQI 62
Query: 285 EEGFGEQLAVIYDSPITGAVQKINYNQLLESVSKLAGVFAKCGITKGDRILIYLPMIPQT 464
EEG GEQ A+IYDSP+TG + +Y +L + V++LAG G+ KGDR++IY+PM+PQ
Sbjct: 63 EEGRGEQTALIYDSPVTGTQDRYSYLRLRDEVARLAGALRALGVGKGDRVIIYMPMVPQA 122
Query: 465 LVTMLACARLGAIHSLVFGGFAAKELAVRIKHCEPKLIVTTNVGVEPNRLIKYTDLVN 638
+ MLACARLGA+HS+VFGGFA ELA+RI PKL++T + G+E +R+I+Y LV+
Sbjct: 123 AMAMLACARLGAVHSVVFGGFAPYELALRIDDATPKLVLTASCGLEFDRVIEYKPLVD 180
>sp|P59871|ACSA_MYCBO Acetyl-coenzyme A synthetase (Acetate--CoA ligase) (Acyl-activating
enzyme)
Length = 651
Score = 156 bits (394), Expect = 5e-38
Identities = 70/158 (44%), Positives = 103/158 (65%)
Frame = +3
Query: 117 FKQSIENKEEFWRKAANEIIWKKPSTQILDTTELHAPKWFNGSELNICHNCVDRHVEEGF 296
++++ E++ FW K AN + W P T++LD +E KWF G ELN+ +NCVDRHVE G
Sbjct: 29 YREAEEDRLAFWAKQANRLSWTTPFTEVLDWSEAPFAKWFVGGELNVAYNCVDRHVEAGH 88
Query: 297 GEQLAVIYDSPITGAVQKINYNQLLESVSKLAGVFAKCGITKGDRILIYLPMIPQTLVTM 476
G+++A+ ++ G + + Y+ LL VSK A G+ GDR+ IYLP+IP+ ++ M
Sbjct: 89 GDRVAIHWEGEPVGDRRTLTYSDLLAEVSKAANALTDLGLVAGDRVAIYLPLIPEAVIAM 148
Query: 477 LACARLGAIHSLVFGGFAAKELAVRIKHCEPKLIVTTN 590
LACARLG +HS+VFGGF A L RI + KL++T +
Sbjct: 149 LACARLGIMHSVVFGGFTAAALQARIVDAQAKLLITAD 186
>sp|Q72LY9|ACSA_LEPIC Acetyl-coenzyme A synthetase (Acetate--CoA ligase) (Acyl-activating
enzyme)
Length = 661
Score = 154 bits (388), Expect = 2e-37
Identities = 75/184 (40%), Positives = 115/184 (62%), Gaps = 4/184 (2%)
Frame = +3
Query: 93 TLTKYQIEFKQSIENKEEFWRKAANEIIWKKPSTQILDTTELHAP-KWFNGSELNICHNC 269
+L Y+ +K+SIEN +FW + AN +IW K T++L +A +WF G +LN+ +NC
Sbjct: 27 SLKNYKSLYKESIENPNKFWAREANRLIWFKKWTKVLSHDFKNAKVEWFKGGKLNVSYNC 86
Query: 270 VDRHVEEGFGEQLAVIYDSPITGAVQKINYNQLLESVSKLAGVFAKCGITKGDRILIYLP 449
+DRH+ + A+I++ + + Y + V++ A + K G+ KGDR+L+YLP
Sbjct: 87 LDRHISTPLKNKAALIWEGDNPTESRVLTYYDVYREVNRFANILKKFGVKKGDRVLVYLP 146
Query: 450 MIPQTLVTMLACARLGAIHSLVFGGFAAKELAVRIKHCEPKLIVTTNVGV---EPNRLIK 620
MIP+ +T+LAC R+GAIHS+VFGGF+ + L RI C+PKL+VT + G +P L K
Sbjct: 147 MIPELAITILACTRIGAIHSVVFGGFSPEALQSRIDDCKPKLVVTADGGFRGGKPIELKK 206
Query: 621 YTDL 632
DL
Sbjct: 207 NVDL 210
>sp|Q8EYG2|ACSA_LEPIN Acetyl-coenzyme A synthetase (Acetate--CoA ligase) (Acyl-activating
enzyme)
Length = 661
Score = 154 bits (388), Expect = 2e-37
Identities = 75/184 (40%), Positives = 115/184 (62%), Gaps = 4/184 (2%)
Frame = +3
Query: 93 TLTKYQIEFKQSIENKEEFWRKAANEIIWKKPSTQILDTTELHAP-KWFNGSELNICHNC 269
+L Y+ +K+SIEN +FW + AN +IW K T++L +A +WF G +LN+ +NC
Sbjct: 27 SLKNYKSLYKESIENPNKFWAREANRLIWFKKWTKVLSHDFKNAKVEWFKGGKLNVSYNC 86
Query: 270 VDRHVEEGFGEQLAVIYDSPITGAVQKINYNQLLESVSKLAGVFAKCGITKGDRILIYLP 449
+DRH+ + A+I++ + + Y + V++ A + K G+ KGDR+L+YLP
Sbjct: 87 LDRHISTPLKNKAALIWEGDNPTESRVLTYYDVYREVNRFANILKKFGVKKGDRVLVYLP 146
Query: 450 MIPQTLVTMLACARLGAIHSLVFGGFAAKELAVRIKHCEPKLIVTTNVGV---EPNRLIK 620
MIP+ +T+LAC R+GAIHS+VFGGF+ + L RI C+PKL+VT + G +P L K
Sbjct: 147 MIPELAITILACTRIGAIHSVVFGGFSPEALQSRIDDCKPKLVVTADGGFRGGKPIELKK 206
Query: 621 YTDL 632
DL
Sbjct: 207 NVDL 210
>sp|O69635|ACSA_MYCTU Acetyl-coenzyme A synthetase (Acetate--CoA ligase) (Acyl-activating
enzyme)
Length = 651
Score = 153 bits (387), Expect = 3e-37
Identities = 69/158 (43%), Positives = 102/158 (64%)
Frame = +3
Query: 117 FKQSIENKEEFWRKAANEIIWKKPSTQILDTTELHAPKWFNGSELNICHNCVDRHVEEGF 296
++++ E++ FW K AN + W P T++LD + KWF G ELN+ +NCVDRHVE G
Sbjct: 29 YREAEEDRLAFWAKQANRLSWTTPFTEVLDWSGAPFAKWFVGGELNVAYNCVDRHVEAGH 88
Query: 297 GEQLAVIYDSPITGAVQKINYNQLLESVSKLAGVFAKCGITKGDRILIYLPMIPQTLVTM 476
G+++A+ ++ G + + Y+ LL VSK A G+ GDR+ IYLP+IP+ ++ M
Sbjct: 89 GDRVAIHWEGEPVGDRRTLTYSDLLAEVSKAANALTDLGLVAGDRVAIYLPLIPEAVIAM 148
Query: 477 LACARLGAIHSLVFGGFAAKELAVRIKHCEPKLIVTTN 590
LACARLG +HS+VFGGF A L RI + KL++T +
Sbjct: 149 LACARLGIMHSVVFGGFTAAALQARIVDAQAKLLITAD 186
>sp|Q8UBV5|ACSA_AGRT5 Acetyl-coenzyme A synthetase (Acetate--CoA ligase) (Acyl-activating
enzyme)
Length = 651
Score = 149 bits (376), Expect = 6e-36
Identities = 75/174 (43%), Positives = 112/174 (64%), Gaps = 2/174 (1%)
Frame = +3
Query: 102 KYQIEFKQSIENKEEFWRKAANEIIWKKPSTQILDTT-ELHAP-KWFNGSELNICHNCVD 275
+YQ +++S+E+ E+FW K I W KP T++ +T+ + P KWF N+ +NC+D
Sbjct: 22 RYQKWYQESVEDPEKFWDKHGRRIDWFKPYTKVKNTSFKGRVPIKWFEDGLTNVSYNCID 81
Query: 276 RHVEEGFGEQLAVIYDSPITGAVQKINYNQLLESVSKLAGVFAKCGITKGDRILIYLPMI 455
RH++ GE+ A+I++ +KI YNQL + V +LA V K G+ KGDR+ IY+PMI
Sbjct: 82 RHLKT-HGERTAIIWEGDNPYIDKKITYNQLYDYVCRLANVLKKHGVKKGDRVTIYMPMI 140
Query: 456 PQTLVTMLACARLGAIHSLVFGGFAAKELAVRIKHCEPKLIVTTNVGVEPNRLI 617
P+ MLACAR+GA+HS+VFGGF+ + LA RI CE ++T + GV + I
Sbjct: 141 PEAAYAMLACARIGAVHSVVFGGFSPEALAGRIVDCESTFVITCDEGVRGGKPI 194
>sp|Q9RRL7|ACSA_DEIRA Acetyl-coenzyme A synthetase (Acetate--CoA ligase) (Acyl-activating
enzyme)
Length = 649
Score = 147 bits (372), Expect = 2e-35
Identities = 65/165 (39%), Positives = 109/165 (66%)
Frame = +3
Query: 102 KYQIEFKQSIENKEEFWRKAANEIIWKKPSTQILDTTELHAPKWFNGSELNICHNCVDRH 281
+Y+ ++QS++ ++FW + A+++ W K ++LD E HA +WF G + NI +N +DR+
Sbjct: 34 EYERRYRQSLDQPDDFWSEVAHDLHWMKDWDRVLDWQEPHA-QWFVGGQTNIAYNALDRN 92
Query: 282 VEEGFGEQLAVIYDSPITGAVQKINYNQLLESVSKLAGVFAKCGITKGDRILIYLPMIPQ 461
V+ G G++ A+I++ G V+ Y +LL V K A + G+ GDR+ +Y+P+IP+
Sbjct: 93 VQRGLGDKRAIIWEGE-DGEVRTYTYAELLREVCKAANALEELGVVAGDRVTLYMPLIPE 151
Query: 462 TLVTMLACARLGAIHSLVFGGFAAKELAVRIKHCEPKLIVTTNVG 596
+ MLACAR+GA+HS+VFGGF+ LA RI + + KL++T + G
Sbjct: 152 AAIAMLACARIGAVHSIVFGGFSVSALADRINNAQSKLLITADAG 196
>sp|Q82EL5|ACSA_STRAW Acetyl-coenzyme A synthetase (Acetate--CoA ligase) (Acyl-activating
enzyme)
Length = 652
Score = 147 bits (371), Expect = 2e-35
Identities = 68/160 (42%), Positives = 103/160 (64%)
Frame = +3
Query: 117 FKQSIENKEEFWRKAANEIIWKKPSTQILDTTELHAPKWFNGSELNICHNCVDRHVEEGF 296
++Q+ ++ FW + A + W T+ LD + KWF +LN+ +NCVDRHVE G
Sbjct: 33 YEQAKADRLGFWAEQARRLTWATEPTETLDWSNPPFAKWFKDGKLNVAYNCVDRHVEAGH 92
Query: 297 GEQLAVIYDSPITGAVQKINYNQLLESVSKLAGVFAKCGITKGDRILIYLPMIPQTLVTM 476
G+++A+ ++ G + I Y +L + VSK A + G+ KGDR+ +YLPMIP+ +V M
Sbjct: 93 GDRVAIHFEGE-PGDSRAITYAELKDEVSKAANALTELGVQKGDRVAVYLPMIPEAVVAM 151
Query: 477 LACARLGAIHSLVFGGFAAKELAVRIKHCEPKLIVTTNVG 596
LACAR+GA HS+VFGGF+A +A RIK + KL++T + G
Sbjct: 152 LACARIGAAHSVVFGGFSADAIAARIKDADAKLVITADGG 191
>sp|Q9KWA3|ACSA_AGRRH Acetyl-coenzyme A synthetase (Acetate--CoA ligase) (Acyl-activating
enzyme)
Length = 652
Score = 146 bits (368), Expect = 5e-35
Identities = 71/178 (39%), Positives = 108/178 (60%), Gaps = 2/178 (1%)
Frame = +3
Query: 72 VNKRSVQTLTKYQIEFKQSIENKEEFWRKAANEIIWKKPSTQILDT--TELHAPKWFNGS 245
V ++ +YQ + +S+ + E+FW K I W KP T + DT T + KWF
Sbjct: 12 VESHALINKAEYQEWYAESVADPEQFWGKHGKRIDWFKPYTSVKDTSFTGDVSIKWFEDG 71
Query: 246 ELNICHNCVDRHVEEGFGEQLAVIYDSPITGAVQKINYNQLLESVSKLAGVFAKCGITKG 425
E N+ +NC+DRH+ G+Q+A+I++ +KI Y +L E V ++A V K G+ KG
Sbjct: 72 ETNVSYNCIDRHLATN-GDQVAIIWEGDDPSLDRKITYRELYEHVCRMANVLKKHGVKKG 130
Query: 426 DRILIYLPMIPQTLVTMLACARLGAIHSLVFGGFAAKELAVRIKHCEPKLIVTTNVGV 599
DR+ IY+PM+P+ MLACAR+GAIHS+VFGGF+ + L RI C+ ++T + G+
Sbjct: 131 DRVTIYMPMVPEAAYAMLACARIGAIHSVVFGGFSPEALGGRIVDCQSTFVITCDEGL 188
>sp|Q9X928|ACSA_STRCO Acetyl-coenzyme A synthetase (Acetate--CoA ligase) (Acyl-activating
enzyme)
Length = 651
Score = 145 bits (365), Expect = 1e-34
Identities = 66/160 (41%), Positives = 104/160 (65%)
Frame = +3
Query: 117 FKQSIENKEEFWRKAANEIIWKKPSTQILDTTELHAPKWFNGSELNICHNCVDRHVEEGF 296
++Q+ ++ FW + A + W K T+ LD + KWF LN+ +NCVDRHVE G
Sbjct: 33 YEQAKADRLGFWAEQARRLTWAKEPTETLDWSNPPFAKWFKDGTLNVAYNCVDRHVEAGN 92
Query: 297 GEQLAVIYDSPITGAVQKINYNQLLESVSKLAGVFAKCGITKGDRILIYLPMIPQTLVTM 476
G+++A+ ++ +G + + Y QL + VSK A + G+ KGDR+ IY+PMIP+T + M
Sbjct: 93 GDRVAIHFEGE-SGDSRALTYAQLKDEVSKAANALLELGVQKGDRVAIYMPMIPETAIAM 151
Query: 477 LACARLGAIHSLVFGGFAAKELAVRIKHCEPKLIVTTNVG 596
LACAR+GA HS+VFGGF++ LA RI+ + ++++T + G
Sbjct: 152 LACARIGAAHSVVFGGFSSDALATRIQDADARVVITADGG 191
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 70,921,524
Number of Sequences: 369166
Number of extensions: 1422194
Number of successful extensions: 3815
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3603
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3691
length of database: 68,354,980
effective HSP length: 106
effective length of database: 48,773,070
effective search space used: 5169945420
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)