Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_008_E15
(837 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P31689|DNJA1_HUMAN DnaJ homolog subfamily A member 1 (He... 309 5e-84
sp|P63036|DNJA1_RAT DnaJ homolog subfamily A member 1 (DnaJ... 309 5e-84
sp|Q8WW22|DNJA4_HUMAN DnaJ homolog subfamily A member 4 308 1e-83
sp|Q9JMC3|DNJA4_MOUSE DnaJ homolog subfamily A member 4 (Mm... 308 2e-83
sp|O60884|DNJA2_HUMAN DnaJ homolog subfamily A member 2 (HI... 288 1e-77
sp|Q9QYJ0|DNJA2_MOUSE DnaJ homolog subfamily A member 2 (mDj3) 287 2e-77
sp|O35824|DNJA2_RAT DnaJ homolog subfamily A member 2 (RDJ2) 285 8e-77
sp|Q03363|DNJH1_ALLPO DnaJ protein homolog 1 (DNAJ-1) 259 6e-69
sp|P42824|DNJH2_ALLPO DnaJ protein homolog 2 254 3e-67
sp|P43644|DNJH_ATRNU DnaJ protein homolog ANJ1 246 4e-65
>sp|P31689|DNJA1_HUMAN DnaJ homolog subfamily A member 1 (Heat shock 40 kDa protein 4)
(DnaJ protein homolog 2) (HSJ-2) (HSDJ)
Length = 397
Score = 309 bits (792), Expect = 5e-84
Identities = 140/232 (60%), Positives = 185/232 (79%)
Frame = +1
Query: 1 DELYKGNTRKLAIQKNVICDKCNGRGGKEGAVQKCNSCRGMGVEVHIRQLGPGMVQQMQT 180
++LY G TRKLA+QKNVICDKC GRGGK+GAV+ C +CRG G+++ I Q+GPGMVQQ+Q+
Sbjct: 116 EDLYNGATRKLALQKNVICDKCEGRGGKKGAVECCPNCRGTGMQIRIHQIGPGMVQQIQS 175
Query: 181 TCRTCKGEREVINERDRCKKCEGQKVVREKKVLEVHIDKGMTDGQQIKFNGEGDQEPGLE 360
C C+G E I+ +DRCK C G+K+VREKK+LEVHIDKGM DGQ+I F+GEGDQEPGLE
Sbjct: 176 VCMECQGHGERISPKDRCKSCNGRKIVREKKILEVHIDKGMKDGQKITFHGEGDQEPGLE 235
Query: 361 PGDICIVLEEKPHNVFTRKKADLIYNMKLDLVDSLCGFKRTITTLDNRILVVETKPGEVI 540
PGDI IVL++K H VFTR+ DL M + LV++LCGF++ I+TLDNR +V+ + PG+++
Sbjct: 236 PGDIIIVLDQKDHAVFTRRGEDLFMCMDIQLVEALCGFQKPISTLDNRTIVITSHPGQIV 295
Query: 541 KNLEYRAIDNEGMPKYKSPFEQGRLIIQFDVVFPENNFLPTDKLNKLRSILP 696
K+ + + + NEGMP Y+ P+E+GRLII+F V FPEN FL DKL+ L +LP
Sbjct: 296 KHGDIKCVLNEGMPIYRRPYEKGRLIIEFKVNFPENGFLSPDKLSLLEKLLP 347
>sp|P63036|DNJA1_RAT DnaJ homolog subfamily A member 1 (DnaJ-like protein 1)
sp|P63037|DNJA1_MOUSE DnaJ homolog subfamily A member 1 (Heat shock 40 kDa protein 4)
(DnaJ protein homolog 2) (HSJ-2)
Length = 397
Score = 309 bits (792), Expect = 5e-84
Identities = 140/232 (60%), Positives = 185/232 (79%)
Frame = +1
Query: 1 DELYKGNTRKLAIQKNVICDKCNGRGGKEGAVQKCNSCRGMGVEVHIRQLGPGMVQQMQT 180
++LY G TRKLA+QKNVICDKC GRGGK+GAV+ C +CRG G+++ I Q+GPGMVQQ+Q+
Sbjct: 116 EDLYNGATRKLALQKNVICDKCEGRGGKKGAVECCPNCRGTGMQIRIHQIGPGMVQQIQS 175
Query: 181 TCRTCKGEREVINERDRCKKCEGQKVVREKKVLEVHIDKGMTDGQQIKFNGEGDQEPGLE 360
C C+G E I+ +DRCK C G+K+VREKK+LEVHIDKGM DGQ+I F+GEGDQEPGLE
Sbjct: 176 VCMECQGHGERISPKDRCKSCNGRKIVREKKILEVHIDKGMKDGQKITFHGEGDQEPGLE 235
Query: 361 PGDICIVLEEKPHNVFTRKKADLIYNMKLDLVDSLCGFKRTITTLDNRILVVETKPGEVI 540
PGDI IVL++K H VFTR+ DL M + LV++LCGF++ I+TLDNR +V+ + PG+++
Sbjct: 236 PGDIIIVLDQKDHAVFTRRGEDLFMCMDIQLVEALCGFQKPISTLDNRTIVITSHPGQIV 295
Query: 541 KNLEYRAIDNEGMPKYKSPFEQGRLIIQFDVVFPENNFLPTDKLNKLRSILP 696
K+ + + + NEGMP Y+ P+E+GRLII+F V FPEN FL DKL+ L +LP
Sbjct: 296 KHGDIKCVLNEGMPIYRRPYEKGRLIIEFKVNFPENGFLSPDKLSLLEKLLP 347
>sp|Q8WW22|DNJA4_HUMAN DnaJ homolog subfamily A member 4
Length = 397
Score = 308 bits (789), Expect = 1e-83
Identities = 140/233 (60%), Positives = 189/233 (81%)
Frame = +1
Query: 1 DELYKGNTRKLAIQKNVICDKCNGRGGKEGAVQKCNSCRGMGVEVHIRQLGPGMVQQMQT 180
++LY G T+KLA+QKNVIC+KC G GGK+G+V+KC C+G G+++HI+Q+GPGMVQQ+QT
Sbjct: 117 EDLYNGVTKKLALQKNVICEKCEGVGGKKGSVEKCPLCKGRGMQIHIQQIGPGMVQQIQT 176
Query: 181 TCRTCKGEREVINERDRCKKCEGQKVVREKKVLEVHIDKGMTDGQQIKFNGEGDQEPGLE 360
C CKG+ E IN +DRC+ C G KV+REKK++EVH++KGM DGQ+I F+GEGDQEP LE
Sbjct: 177 VCIECKGQGERINPKDRCESCSGAKVIREKKIIEVHVEKGMKDGQKILFHGEGDQEPELE 236
Query: 361 PGDICIVLEEKPHNVFTRKKADLIYNMKLDLVDSLCGFKRTITTLDNRILVVETKPGEVI 540
PGD+ IVL++K H+VF R+ DLI MK+ L ++LCGFK+TI TLDNRILV+ +K GEVI
Sbjct: 237 PGDVIIVLDQKDHSVFQRRGHDLIMKMKIQLSEALCGFKKTIKTLDNRILVITSKAGEVI 296
Query: 541 KNLEYRAIDNEGMPKYKSPFEQGRLIIQFDVVFPENNFLPTDKLNKLRSILPP 699
K+ + R + +EGMP YK+P E+G LIIQF V+FPE ++L +KL +L ++LPP
Sbjct: 297 KHGDLRCVRDEGMPIYKAPLEKGILIIQFLVIFPEKHWLSLEKLPQLEALLPP 349
>sp|Q9JMC3|DNJA4_MOUSE DnaJ homolog subfamily A member 4 (MmDjA4)
Length = 397
Score = 308 bits (788), Expect = 2e-83
Identities = 149/279 (53%), Positives = 203/279 (72%)
Frame = +1
Query: 1 DELYKGNTRKLAIQKNVICDKCNGRGGKEGAVQKCNSCRGMGVEVHIRQLGPGMVQQMQT 180
++LY G T+KLA+QKNVIC+KC G GGK+G+V+KC C+G G++VHI+Q+GPGMVQQ+QT
Sbjct: 117 EDLYNGITKKLALQKNVICEKCEGIGGKKGSVEKCPLCKGRGMQVHIQQIGPGMVQQIQT 176
Query: 181 TCRTCKGEREVINERDRCKKCEGQKVVREKKVLEVHIDKGMTDGQQIKFNGEGDQEPGLE 360
C CKG+ E IN +DRC+ C G KV REKK++EVH++KGM DGQ+I F+GEGDQEP L+
Sbjct: 177 VCIECKGQGERINPKDRCENCSGAKVTREKKIIEVHVEKGMKDGQKILFHGEGDQEPELD 236
Query: 361 PGDICIVLEEKPHNVFTRKKADLIYNMKLDLVDSLCGFKRTITTLDNRILVVETKPGEVI 540
PGD+ IVL++K H+VF R+ DLI MK+ L ++LCGFK+TI TLD+R+LV+ +K GEVI
Sbjct: 237 PGDVIIVLDQKDHSVFQRRGQDLIMKMKIQLSEALCGFKKTIKTLDDRVLVISSKSGEVI 296
Query: 541 KNLEYRAIDNEGMPKYKSPFEQGRLIIQFDVVFPENNFLPTDKLNKLRSILPPFTVFIIT 720
K+ + + I NEGMP YK+P E+G +IIQF VVFPE +L +KL +L ++LPP IT
Sbjct: 297 KHGDLKCIRNEGMPIYKAPLEKGVMIIQFLVVFPEKQWLSQEKLPQLEALLPPRQKVRIT 356
Query: 721 R*YERSRGMCFASLRSKHGNSKSQDRYHERHHVYDSDDE 837
M L+ + N +S + + Y+ DDE
Sbjct: 357 ------DDMDQVELKEFNPNEQS---WRQHREAYEEDDE 386
>sp|O60884|DNJA2_HUMAN DnaJ homolog subfamily A member 2 (HIRA interacting protein 4)
(Cell cycle progression restoration gene 3 protein)
(Dnj3)
Length = 412
Score = 288 bits (737), Expect = 1e-77
Identities = 134/232 (57%), Positives = 174/232 (75%)
Frame = +1
Query: 1 DELYKGNTRKLAIQKNVICDKCNGRGGKEGAVQKCNSCRGMGVEVHIRQLGPGMVQQMQT 180
++LY G T KL + KNV+C C+G+GGK GAVQKC++CRG GV + IRQL PGMVQQMQ+
Sbjct: 125 EDLYNGKTTKLQLSKNVLCSACSGQGGKSGAVQKCSACRGRGVRIMIRQLAPGMVQQMQS 184
Query: 181 TCRTCKGEREVINERDRCKKCEGQKVVREKKVLEVHIDKGMTDGQQIKFNGEGDQEPGLE 360
C C GE EVINE+DRCKKCEG+KV++E K+LEVH+DKGM GQ+I F GE DQ PG+E
Sbjct: 185 VCSDCNGEGEVINEKDRCKKCEGKKVIKEVKILEVHVDKGMKHGQRITFTGEADQAPGVE 244
Query: 361 PGDICIVLEEKPHNVFTRKKADLIYNMKLDLVDSLCGFKRTITTLDNRILVVETKPGEVI 540
PGDI ++L+EK H VF R DL K+ LV++LCGF+ T LD R +VV+ PG+VI
Sbjct: 245 PGDIVLLLQEKEHEVFQRDGNDLHMTYKIGLVEALCGFQFTFKHLDGRQIVVKYPPGKVI 304
Query: 541 KNLEYRAIDNEGMPKYKSPFEQGRLIIQFDVVFPENNFLPTDKLNKLRSILP 696
+ R + EGMP+Y++PFE+G L I+FDV FPENN++ DKL++L +LP
Sbjct: 305 EPGCVRVVRGEGMPQYRNPFEKGDLYIKFDVQFPENNWINPDKLSELEDLLP 356
>sp|Q9QYJ0|DNJA2_MOUSE DnaJ homolog subfamily A member 2 (mDj3)
Length = 412
Score = 287 bits (735), Expect = 2e-77
Identities = 134/232 (57%), Positives = 174/232 (75%)
Frame = +1
Query: 1 DELYKGNTRKLAIQKNVICDKCNGRGGKEGAVQKCNSCRGMGVEVHIRQLGPGMVQQMQT 180
++LY G T KL + KNV+C C+G+GGK GAVQKC++CRG GV + IRQL PGMVQQMQ+
Sbjct: 125 EDLYNGKTTKLQLSKNVLCSACSGQGGKSGAVQKCSACRGRGVRIMIRQLAPGMVQQMQS 184
Query: 181 TCRTCKGEREVINERDRCKKCEGQKVVREKKVLEVHIDKGMTDGQQIKFNGEGDQEPGLE 360
C C GE EVINE+DRCKKCEG+KV++E K+LEVH+DKGM GQ+I F GE DQ PG+E
Sbjct: 185 VCSDCNGEGEVINEKDRCKKCEGKKVIKEVKILEVHVDKGMKHGQRITFTGEADQAPGVE 244
Query: 361 PGDICIVLEEKPHNVFTRKKADLIYNMKLDLVDSLCGFKRTITTLDNRILVVETKPGEVI 540
PGDI ++L+EK H VF R DL K+ LV++LCGF+ T LD R +VV+ PG+VI
Sbjct: 245 PGDIVLLLQEKEHEVFQRDGNDLHMTYKIGLVEALCGFQFTFKHLDARQIVVKYPPGKVI 304
Query: 541 KNLEYRAIDNEGMPKYKSPFEQGRLIIQFDVVFPENNFLPTDKLNKLRSILP 696
+ R + EGMP+Y++PFE+G L I+FDV FPENN++ DKL++L +LP
Sbjct: 305 EPGCVRVVRGEGMPQYRNPFEKGDLYIKFDVQFPENNWINPDKLSELEDLLP 356
>sp|O35824|DNJA2_RAT DnaJ homolog subfamily A member 2 (RDJ2)
Length = 412
Score = 285 bits (730), Expect = 8e-77
Identities = 133/232 (57%), Positives = 173/232 (74%)
Frame = +1
Query: 1 DELYKGNTRKLAIQKNVICDKCNGRGGKEGAVQKCNSCRGMGVEVHIRQLGPGMVQQMQT 180
++LY G T KL + KNV+C C+G+GGK GAVQKC++CRG GV + IRQL PGMVQQMQ+
Sbjct: 125 EDLYNGKTTKLQLSKNVLCSACSGQGGKSGAVQKCSACRGRGVRIMIRQLAPGMVQQMQS 184
Query: 181 TCRTCKGEREVINERDRCKKCEGQKVVREKKVLEVHIDKGMTDGQQIKFNGEGDQEPGLE 360
C C GE EVINE+DRCKKCEG+KV++E K+LEVH+DKGM GQ+I F GE DQ PG+E
Sbjct: 185 VCSDCNGEGEVINEKDRCKKCEGKKVIKEVKILEVHVDKGMKHGQRITFTGEADQAPGVE 244
Query: 361 PGDICIVLEEKPHNVFTRKKADLIYNMKLDLVDSLCGFKRTITTLDNRILVVETKPGEVI 540
PGDI + ++EK H VF R DL K+ LV++LCGF+ T LD R +VV+ PG+VI
Sbjct: 245 PGDIVLFVQEKEHEVFQRDGNDLHMTYKIGLVEALCGFQFTFKHLDARQIVVKYPPGKVI 304
Query: 541 KNLEYRAIDNEGMPKYKSPFEQGRLIIQFDVVFPENNFLPTDKLNKLRSILP 696
+ R + EGMP+Y++PFE+G L I+FDV FPENN++ DKL++L +LP
Sbjct: 305 EPGCVRVVRGEGMPQYRNPFEKGDLYIKFDVQFPENNWINPDKLSELEDLLP 356
>sp|Q03363|DNJH1_ALLPO DnaJ protein homolog 1 (DNAJ-1)
Length = 397
Score = 259 bits (662), Expect = 6e-69
Identities = 130/281 (46%), Positives = 182/281 (64%), Gaps = 2/281 (0%)
Frame = +1
Query: 1 DELYKGNTRKLAIQKNVICDKCNGRGGKEGAVQKCNSCRGMGVEVHIRQLGPGMVQQMQT 180
+ELY G ++KL++ +NVIC KCNG+G K GA +C SC+G G++V IRQLGPGM+QQMQ
Sbjct: 109 EELYNGTSKKLSLSRNVICSKCNGKGSKSGASMRCASCQGSGMKVSIRQLGPGMIQQMQH 168
Query: 181 TCRTCKGEREVINERDRCKKCEGQKVVREKKVLEVHIDKGMTDGQQIKFNGEGDQEPGLE 360
C CKG E+IN++DRC C+G+KVV+EKKVLEVH++KGM +GQ+I F GE D+ P
Sbjct: 169 PCNDCKGTGEMINDKDRCPLCKGEKVVQEKKVLEVHVEKGMQNGQRITFPGEADEAPDTV 228
Query: 361 PGDICIVLEEKPHNVFTRKKADLIYNMKLDLVDSLCGFKRTITTLDNRILVVETKPGEVI 540
GDI VL++K H F RK DL Y L L ++LCGF+ +T LD R L++++ PGEV+
Sbjct: 229 TGDIVFVLQQKEHPKFQRKGDDLFYKHTLSLTEALCGFQFVLTHLDGRQLLIKSNPGEVV 288
Query: 541 KNLEYRAIDNEGMPKYKSPFEQGRLIIQFDVVFPENNFLPTDKLNKLRSILPPFTVFIIT 720
K +++AI++EGMP Y+ PF +G+L IQF V FP++ L D+ + S+LP +T
Sbjct: 289 KPDQFKAINDEGMPMYQRPFMRGKLYIQFLVDFPDS--LTPDQCKVIESVLPRSASSQLT 346
Query: 721 R*YERSRGMCFASLRSKHGNSKSQDRYHERH--HVYDSDDE 837
+ C + + R +H YD DDE
Sbjct: 347 ---DMEIDECEETTMHDVNIEEEMRRKQHQHAQEAYDEDDE 384
>sp|P42824|DNJH2_ALLPO DnaJ protein homolog 2
Length = 418
Score = 254 bits (648), Expect = 3e-67
Identities = 117/232 (50%), Positives = 166/232 (71%)
Frame = +1
Query: 1 DELYKGNTRKLAIQKNVICDKCNGRGGKEGAVQKCNSCRGMGVEVHIRQLGPGMVQQMQT 180
++LY G ++KL++ +NV+C KC G+G K GA C SC+G G++V IRQLGPGM+QQMQ
Sbjct: 130 EDLYNGTSKKLSLSRNVLCTKCKGKGSKSGASMNCASCQGSGMKVSIRQLGPGMIQQMQH 189
Query: 181 TCRTCKGEREVINERDRCKKCEGQKVVREKKVLEVHIDKGMTDGQQIKFNGEGDQEPGLE 360
C CKG E+I+++DRC +C+G+KVV++KKVLEVH++KGM +GQ+I F GE D+ P
Sbjct: 190 PCNECKGTGEMISDKDRCPQCKGEKVVQQKKVLEVHVEKGMQNGQKITFPGEADEAPDTV 249
Query: 361 PGDICIVLEEKPHNVFTRKKADLIYNMKLDLVDSLCGFKRTITTLDNRILVVETKPGEVI 540
GDI VL++K H F RK DL Y L L ++LCGF+ +T LDNR L++++ PGEVI
Sbjct: 250 TGDIVFVLQQKEHPKFKRKGDDLFYEHSLSLTEALCGFQFVLTHLDNRQLLIKSNPGEVI 309
Query: 541 KNLEYRAIDNEGMPKYKSPFEQGRLIIQFDVVFPENNFLPTDKLNKLRSILP 696
K +++ I++EGMP Y+ PF +G+L I F V FP++ L D+ L S+LP
Sbjct: 310 KPDQFKGINDEGMPMYQRPFMRGKLYIHFSVDFPDS--LTPDQCKALESVLP 359
>sp|P43644|DNJH_ATRNU DnaJ protein homolog ANJ1
Length = 417
Score = 246 bits (629), Expect = 4e-65
Identities = 115/233 (49%), Positives = 163/233 (69%)
Frame = +1
Query: 1 DELYKGNTRKLAIQKNVICDKCNGRGGKEGAVQKCNSCRGMGVEVHIRQLGPGMVQQMQT 180
++L+ G T+KL++ +NVIC KC G+G K GA KC+ C+G G++V IR LGP M+QQMQ
Sbjct: 130 EDLFTGTTKKLSLSRNVICSKCTGKGSKSGASMKCSGCQGTGMKVSIRHLGPSMIQQMQH 189
Query: 181 TCRTCKGEREVINERDRCKKCEGQKVVREKKVLEVHIDKGMTDGQQIKFNGEGDQEPGLE 360
C CKG E IN++DRC +C+G+KVV+EKKVLEV ++KGM GQ+I F GE D+ P
Sbjct: 190 PCNECKGTGETINDKDRCPQCKGEKVVQEKKVLEVVVEKGMQHGQKITFPGEADEAPDTV 249
Query: 361 PGDICIVLEEKPHNVFTRKKADLIYNMKLDLVDSLCGFKRTITTLDNRILVVETKPGEVI 540
GDI VL++K H F RK DL Y L L ++LCGF+ +T LD R L++++ GEV+
Sbjct: 250 TGDIVFVLQQKEHPKFKRKGEDLFYEHTLSLTEALCGFRFVLTHLDGRQLLIKSNLGEVV 309
Query: 541 KNLEYRAIDNEGMPKYKSPFEQGRLIIQFDVVFPENNFLPTDKLNKLRSILPP 699
K +++AI++EGMP Y+ PF +G++ I F V FP++ L D++ L +ILPP
Sbjct: 310 KPDQFKAIEDEGMPIYQRPFMKGKMYIHFTVEFPDS--LNPDQVKSLEAILPP 360
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 89,329,172
Number of Sequences: 369166
Number of extensions: 1776167
Number of successful extensions: 5884
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5160
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5360
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 8148988185
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)