Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_008_E04
(324 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q10991|CATL_SHEEP Cathepsin L [Contains: Cathepsin L hea... 145 2e-35
sp|Q9GL24|CATL_CANFA Cathepsin L precursor [Contains: Cathe... 143 1e-34
sp|P06797|CATL_MOUSE Cathepsin L precursor (Major excreted ... 142 2e-34
sp|P25975|CATL_BOVIN Cathepsin L precursor [Contains: Cathe... 142 2e-34
sp|O60911|CATL2_HUMAN Cathepsin L2 precursor (Cathepsin V) ... 142 2e-34
sp|Q28944|CATL_PIG Cathepsin L precursor [Contains: Catheps... 141 4e-34
sp|P07154|CATL_RAT Cathepsin L precursor (Major excreted pr... 139 2e-33
sp|Q26636|CATL_SARPE Cathepsin L precursor [Contains: Cathe... 136 1e-32
sp|P07711|CATL_HUMAN Cathepsin L precursor (Major excreted ... 134 5e-32
sp|Q9JIA9|CATR_MOUSE Cathepsin R precursor 133 1e-31
>sp|Q10991|CATL_SHEEP Cathepsin L [Contains: Cathepsin L heavy chain; Cathepsin L light
chain]
Length = 217
Score = 145 bits (367), Expect = 2e-35
Identities = 69/94 (73%), Positives = 76/94 (80%), Gaps = 1/94 (1%)
Frame = +2
Query: 5 KAVATVGPISVAIDASRPSFQLYKGGIYNEVNCSSNNLDHGVLAVGYGAEGKNH-FWIVK 181
KAVATVGPISVAIDA SFQ YK GIY + +CSS +LDHGVL VGYG EG N+ FWIVK
Sbjct: 124 KAVATVGPISVAIDAGHSSFQFYKSGIYYDPDCSSKDLDHGVLVVGYGFEGTNNKFWIVK 183
Query: 182 NSWGPTWGISGYIKMSKDKKNQCGIATMASYPTV 283
NSWGP WG GY+KM+KD+ N CGIAT ASYPTV
Sbjct: 184 NSWGPEWGNKGYVKMAKDQNNHCGIATAASYPTV 217
>sp|Q9GL24|CATL_CANFA Cathepsin L precursor [Contains: Cathepsin L heavy chain; Cathepsin
L light chain]
Length = 333
Score = 143 bits (361), Expect = 1e-34
Identities = 68/96 (70%), Positives = 76/96 (79%), Gaps = 3/96 (3%)
Frame = +2
Query: 5 KAVATVGPISVAIDASRPSFQLYKGGIYNEVNCSSNNLDHGVLAVGYGAEG---KNHFWI 175
KAVAT+GPISVAIDA SFQ YK GIY + +CSS +LDHGVL VGYG EG N FWI
Sbjct: 238 KAVATLGPISVAIDAGHQSFQFYKSGIYFDPDCSSKDLDHGVLVVGYGFEGTDSNNKFWI 297
Query: 176 VKNSWGPTWGISGYIKMSKDKKNQCGIATMASYPTV 283
VKNSWGP WG +GY+KM+KD+ N CGIAT ASYPTV
Sbjct: 298 VKNSWGPEWGWNGYVKMAKDQNNHCGIATAASYPTV 333
>sp|P06797|CATL_MOUSE Cathepsin L precursor (Major excreted protein) (MEP) (p39 cysteine
proteinase) [Contains: Cathepsin L heavy chain;
Cathepsin L light chain]
Length = 334
Score = 142 bits (359), Expect = 2e-34
Identities = 67/97 (69%), Positives = 75/97 (77%), Gaps = 4/97 (4%)
Frame = +2
Query: 5 KAVATVGPISVAIDASRPSFQLYKGGIYNEVNCSSNNLDHGVLAVGYGAEG----KNHFW 172
KAVATVGPISVA+DAS PS Q Y GIY E NCSS NLDHGVL VGYG EG KN +W
Sbjct: 237 KAVATVGPISVAMDASHPSLQFYSSGIYYEPNCSSKNLDHGVLLVGYGYEGTDSNKNKYW 296
Query: 173 IVKNSWGPTWGISGYIKMSKDKKNQCGIATMASYPTV 283
+VKNSWG WG+ GYIK++KD+ N CG+AT ASYP V
Sbjct: 297 LVKNSWGSEWGMEGYIKIAKDRDNHCGLATAASYPVV 333
>sp|P25975|CATL_BOVIN Cathepsin L precursor [Contains: Cathepsin L heavy chain; Cathepsin
L light chain]
Length = 334
Score = 142 bits (359), Expect = 2e-34
Identities = 68/97 (70%), Positives = 75/97 (77%), Gaps = 4/97 (4%)
Frame = +2
Query: 5 KAVATVGPISVAIDASRPSFQLYKGGIYNEVNCSSNNLDHGVLAVGYGAEG----KNHFW 172
KAVATVGPISVAIDA SFQ YK GIY + +CS +LDHGVL VGYG EG N FW
Sbjct: 238 KAVATVGPISVAIDAGHTSFQFYKSGIYYDPDCSCKDLDHGVLVVGYGFEGTDSNNNKFW 297
Query: 173 IVKNSWGPTWGISGYIKMSKDKKNQCGIATMASYPTV 283
IVKNSWGP WG +GY+KM+KD+ N CGIAT ASYPTV
Sbjct: 298 IVKNSWGPEWGWNGYVKMAKDQNNHCGIATAASYPTV 334
>sp|O60911|CATL2_HUMAN Cathepsin L2 precursor (Cathepsin V) (Cathepsin U)
Length = 334
Score = 142 bits (358), Expect = 2e-34
Identities = 67/97 (69%), Positives = 75/97 (77%), Gaps = 4/97 (4%)
Frame = +2
Query: 5 KAVATVGPISVAIDASRPSFQLYKGGIYNEVNCSSNNLDHGVLAVGYGAEGKN----HFW 172
KAVATVGPISVA+DA SFQ YK GIY E +CSS NLDHGVL VGYG EG N +W
Sbjct: 238 KAVATVGPISVAMDAGHSSFQFYKSGIYFEPDCSSKNLDHGVLVVGYGFEGANSNNSKYW 297
Query: 173 IVKNSWGPTWGISGYIKMSKDKKNQCGIATMASYPTV 283
+VKNSWGP WG +GY+K++KDK N CGIAT ASYP V
Sbjct: 298 LVKNSWGPEWGSNGYVKIAKDKNNHCGIATAASYPNV 334
>sp|Q28944|CATL_PIG Cathepsin L precursor [Contains: Cathepsin L heavy chain; Cathepsin
L light chain]
Length = 334
Score = 141 bits (356), Expect = 4e-34
Identities = 67/97 (69%), Positives = 76/97 (78%), Gaps = 4/97 (4%)
Frame = +2
Query: 5 KAVATVGPISVAIDASRPSFQLYKGGIYNEVNCSSNNLDHGVLAVGYGAEG----KNHFW 172
KAVATVGPISVAIDA SFQ YK GIY + +CSS +LDHGVL VGYG EG + FW
Sbjct: 238 KAVATVGPISVAIDAGHSSFQFYKSGIYYDPDCSSKDLDHGVLVVGYGFEGTDSNSSKFW 297
Query: 173 IVKNSWGPTWGISGYIKMSKDKKNQCGIATMASYPTV 283
IVKNSWGP WG +GY+KM+KD+ N CGI+T ASYPTV
Sbjct: 298 IVKNSWGPEWGWNGYVKMAKDQNNHCGISTAASYPTV 334
>sp|P07154|CATL_RAT Cathepsin L precursor (Major excreted protein) (MEP) (Cyclic
protein 2) (CP-2) [Contains: Cathepsin L heavy chain;
Cathepsin L light chain]
Length = 334
Score = 139 bits (350), Expect = 2e-33
Identities = 65/97 (67%), Positives = 75/97 (77%), Gaps = 4/97 (4%)
Frame = +2
Query: 5 KAVATVGPISVAIDASRPSFQLYKGGIYNEVNCSSNNLDHGVLAVGYGAEG----KNHFW 172
KAVATVGPISVA+DAS PS Q Y GIY E NCSS +LDHGVL VGYG EG K+ +W
Sbjct: 237 KAVATVGPISVAMDASHPSLQFYSSGIYYEPNCSSKDLDHGVLVVGYGYEGTDSNKDKYW 296
Query: 173 IVKNSWGPTWGISGYIKMSKDKKNQCGIATMASYPTV 283
+VKNSWG WG+ GYIK++KD+ N CG+AT ASYP V
Sbjct: 297 LVKNSWGKEWGMDGYIKIAKDRNNHCGLATAASYPIV 333
>sp|Q26636|CATL_SARPE Cathepsin L precursor [Contains: Cathepsin L heavy chain; Cathepsin
L light chain]
Length = 339
Score = 136 bits (343), Expect = 1e-32
Identities = 63/94 (67%), Positives = 73/94 (77%), Gaps = 1/94 (1%)
Frame = +2
Query: 5 KAVATVGPISVAIDASRPSFQLYKGGIYNEVNCSSNNLDHGVLAVGYGA-EGKNHFWIVK 181
KAVAT+GP+SVAIDAS SFQLY G+YNE C NLDHGVL VGYG E +W+VK
Sbjct: 246 KAVATMGPVSVAIDASHESFQLYSEGVYNEPECDEQNLDHGVLVVGYGTDESGMDYWLVK 305
Query: 182 NSWGPTWGISGYIKMSKDKKNQCGIATMASYPTV 283
NSWG TWG GYIKM++++ NQCGIAT +SYPTV
Sbjct: 306 NSWGTTWGEQGYIKMARNQNNQCGIATASSYPTV 339
>sp|P07711|CATL_HUMAN Cathepsin L precursor (Major excreted protein) (MEP) [Contains:
Cathepsin L heavy chain; Cathepsin L light chain]
Length = 333
Score = 134 bits (338), Expect = 5e-32
Identities = 63/97 (64%), Positives = 74/97 (76%), Gaps = 4/97 (4%)
Frame = +2
Query: 5 KAVATVGPISVAIDASRPSFQLYKGGIYNEVNCSSNNLDHGVLAVGYGAEG----KNHFW 172
KAVATVGPISVAIDA SF YK GIY E +CSS ++DHGVL VGYG E N +W
Sbjct: 237 KAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYW 296
Query: 173 IVKNSWGPTWGISGYIKMSKDKKNQCGIATMASYPTV 283
+VKNSWG WG+ GY+KM+KD++N CGIA+ ASYPTV
Sbjct: 297 LVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV 333
>sp|Q9JIA9|CATR_MOUSE Cathepsin R precursor
Length = 334
Score = 133 bits (334), Expect = 1e-31
Identities = 59/96 (61%), Positives = 74/96 (77%), Gaps = 4/96 (4%)
Frame = +2
Query: 8 AVATVGPISVAIDASRPSFQLYKGGIYNEVNCSSNNLDHGVLAVGYGAEG----KNHFWI 175
AVAT+GPI+ IDAS SF+ YKGGIY+E NCSS+ + HGVL VGYG +G NH+W+
Sbjct: 239 AVATIGPITAGIDASHESFKNYKGGIYHEPNCSSDTVTHGVLVVGYGFKGIETDGNHYWL 298
Query: 176 VKNSWGPTWGISGYIKMSKDKKNQCGIATMASYPTV 283
+KNSWG WGI GY+K++KDK N CGIA+ A YPT+
Sbjct: 299 IKNSWGKRWGIRGYMKLAKDKNNHCGIASYAHYPTI 334
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 37,601,050
Number of Sequences: 369166
Number of extensions: 735847
Number of successful extensions: 2165
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 1977
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2007
length of database: 68,354,980
effective HSP length: 76
effective length of database: 54,315,120
effective search space used: 1683768720
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)