Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= Dr_sW_008_D15 (518 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|P97742|CPT1A_MOUSE Carnitine O-palmitoyltransferase I, m... 150 2e-36 sp|Q68Y62|CPT1A_HORSE Carnitine O-palmitoyltransferase I, m... 149 4e-36 sp|P32198|CPT1A_RAT Carnitine O-palmitoyltransferase I, mit... 147 1e-35 sp|Q924X2|CPT1B_MOUSE Carnitine O-palmitoyltransferase I, m... 141 8e-34 sp|Q92523|CPT1B_HUMAN Carnitine O-palmitoyltransferase I, m... 140 1e-33 sp|P50416|CPT1A_HUMAN Carnitine O-palmitoyltransferase I, m... 140 2e-33 sp|Q63704|CPT1B_RAT Carnitine O-palmitoyltransferase I, mit... 139 5e-33 sp|Q8HY46|CPT1B_PIG Carnitine O-palmitoyltransferase I, mit... 137 2e-32 sp|Q8BGD5|CPT1C_MOUSE Carnitine O-palmitoyltransferase I, m... 131 1e-30 sp|Q8TCG5|CPT1C_HUMAN Carnitine O-palmitoyltransferase I, m... 130 1e-30
>sp|P97742|CPT1A_MOUSE Carnitine O-palmitoyltransferase I, mitochondrial liver isoform (CPT I) (CPTI-L) (Carnitine palmitoyltransferase 1A) Length = 773 Score = 150 bits (379), Expect = 2e-36 Identities = 75/140 (53%), Positives = 96/140 (68%) Frame = +1 Query: 16 KIRLFRRSCDMHQFLYREAMAGNGIDRHLFALFILSKGLGYDCEFLKDVLSSPWTLSTSQ 195 + +LF+ +C+ HQ LYR AM G GIDRHLF L+++SK L D FLK+VLS PW LSTSQ Sbjct: 629 RFKLFKIACEKHQHLYRLAMTGAGIDRHLFCLYVVSKYLAVDSPFLKEVLSEPWRLSTSQ 688 Query: 196 QPQQQINTGIDCDLPEYRDCVGPGGGFGPVSDNGYGVAYMFPGNFRFFFHISCNKSSPET 375 PQQQ+ D +Y D V GGGFGPV+D+GYGV+Y+ G FHIS SSPET Sbjct: 689 TPQQQVEL---FDFEKYPDYVSCGGGFGPVADDGYGVSYIIVGENFIHFHISSKFSSPET 745 Query: 376 DSNKFGDMIYKSLYDIKALF 435 DS++FG + +++ DI LF Sbjct: 746 DSHRFGKHLRQAMMDIITLF 765
>sp|Q68Y62|CPT1A_HORSE Carnitine O-palmitoyltransferase I, mitochondrial liver isoform (CPT I) (CPTI-L) (Carnitine palmitoyltransferase 1A) Length = 776 Score = 149 bits (376), Expect = 4e-36 Identities = 76/140 (54%), Positives = 97/140 (69%) Frame = +1 Query: 16 KIRLFRRSCDMHQFLYREAMAGNGIDRHLFALFILSKGLGYDCEFLKDVLSSPWTLSTSQ 195 K+RLF+ + + HQ LYR AM G+GIDRHLF L+++SK L D FLK+VLS PW LSTSQ Sbjct: 629 KLRLFKIASEKHQHLYRLAMTGSGIDRHLFCLYVVSKYLAVDSPFLKEVLSEPWRLSTSQ 688 Query: 196 QPQQQINTGIDCDLPEYRDCVGPGGGFGPVSDNGYGVAYMFPGNFRFFFHISCNKSSPET 375 PQQQ+ DL + V GGGFGPV+D+GYGV+Y+ G FHIS SSPET Sbjct: 689 TPQQQVEL---FDLERNPEYVSSGGGFGPVADDGYGVSYILVGENLINFHISSKFSSPET 745 Query: 376 DSNKFGDMIYKSLYDIKALF 435 DS++FG + +++ DI ALF Sbjct: 746 DSHRFGKHLKQAMNDIMALF 765
>sp|P32198|CPT1A_RAT Carnitine O-palmitoyltransferase I, mitochondrial liver isoform (CPT I) (CPTI-L) (Carnitine palmitoyltransferase 1A) Length = 773 Score = 147 bits (372), Expect = 1e-35 Identities = 74/140 (52%), Positives = 96/140 (68%) Frame = +1 Query: 16 KIRLFRRSCDMHQFLYREAMAGNGIDRHLFALFILSKGLGYDCEFLKDVLSSPWTLSTSQ 195 +++LF+ +C+ HQ LYR AM G GIDRHLF L+++SK L D FLK+VLS PW LSTSQ Sbjct: 629 RLKLFKIACEKHQHLYRLAMTGAGIDRHLFCLYVVSKYLAVDSPFLKEVLSEPWRLSTSQ 688 Query: 196 QPQQQINTGIDCDLPEYRDCVGPGGGFGPVSDNGYGVAYMFPGNFRFFFHISCNKSSPET 375 PQQQ+ D + D V GGGFGPV+D+GYGV+Y+ G FHIS SSPET Sbjct: 689 TPQQQVEL---FDFEKNPDYVSCGGGFGPVADDGYGVSYIIVGENFIHFHISSKFSSPET 745 Query: 376 DSNKFGDMIYKSLYDIKALF 435 DS++FG + +++ DI LF Sbjct: 746 DSHRFGKHLRQAMMDIITLF 765
>sp|Q924X2|CPT1B_MOUSE Carnitine O-palmitoyltransferase I, mitochondrial muscle isoform (CPT I) (CPTI-M) (Carnitine palmitoyltransferase 1B) Length = 772 Score = 141 bits (356), Expect = 8e-34 Identities = 74/137 (54%), Positives = 94/137 (68%) Frame = +1 Query: 25 LFRRSCDMHQFLYREAMAGNGIDRHLFALFILSKGLGYDCEFLKDVLSSPWTLSTSQQPQ 204 LFR++ + HQ +YR AM G GIDRHLF L+I+SK LG FL +VLS PW+LSTSQ PQ Sbjct: 632 LFRKASEKHQNMYRLAMTGAGIDRHLFCLYIVSKYLGVSSPFLAEVLSEPWSLSTSQIPQ 691 Query: 205 QQINTGIDCDLPEYRDCVGPGGGFGPVSDNGYGVAYMFPGNFRFFFHISCNKSSPETDSN 384 QI D +Y + +G GGGFGPV+D+GYGV+YM G FFHIS SS ET++ Sbjct: 692 FQI---CMFDPKQYPNHLGAGGGFGPVADDGYGVSYMIAGENTMFFHISSKYSSSETNAQ 748 Query: 385 KFGDMIYKSLYDIKALF 435 +FG+ I ++L DI LF Sbjct: 749 RFGNHIRQALLDIAELF 765
>sp|Q92523|CPT1B_HUMAN Carnitine O-palmitoyltransferase I, mitochondrial muscle isoform (CPT I) (CPTI-M) (Carnitine palmitoyltransferase 1B) (Carnitine palmitoyltransferase I like protein) Length = 772 Score = 140 bits (354), Expect = 1e-33 Identities = 73/141 (51%), Positives = 94/141 (66%) Frame = +1 Query: 25 LFRRSCDMHQFLYREAMAGNGIDRHLFALFILSKGLGYDCEFLKDVLSSPWTLSTSQQPQ 204 LF+++ HQ +YR AM G GIDRHLF L+++SK LG FL +VLS PW LSTSQ PQ Sbjct: 632 LFQKAAKKHQNMYRLAMTGAGIDRHLFCLYLVSKYLGVSSPFLAEVLSEPWRLSTSQIPQ 691 Query: 205 QQINTGIDCDLPEYRDCVGPGGGFGPVSDNGYGVAYMFPGNFRFFFHISCNKSSPETDSN 384 QI D ++ + +G GGGFGPV+D+GYGV+YM G FFHIS SS ET++ Sbjct: 692 SQIRM---FDPEQHPNHLGAGGGFGPVADDGYGVSYMIAGENTIFFHISSKFSSSETNAQ 748 Query: 385 KFGDMIYKSLYDIKALFDGPQ 447 +FG+ I K+L DI LF P+ Sbjct: 749 RFGNHIRKALLDIADLFQVPK 769
>sp|P50416|CPT1A_HUMAN Carnitine O-palmitoyltransferase I, mitochondrial liver isoform (CPT I) (CPTI-L) (Carnitine palmitoyltransferase 1A) Length = 773 Score = 140 bits (353), Expect = 2e-33 Identities = 70/140 (50%), Positives = 95/140 (67%) Frame = +1 Query: 16 KIRLFRRSCDMHQFLYREAMAGNGIDRHLFALFILSKGLGYDCEFLKDVLSSPWTLSTSQ 195 +++LF+ + + HQ +YR AM G+GIDRHLF L+++SK L + FLK+VLS PW LSTSQ Sbjct: 629 RLKLFKLASEKHQHMYRLAMTGSGIDRHLFCLYVVSKYLAVESPFLKEVLSEPWRLSTSQ 688 Query: 196 QPQQQINTGIDCDLPEYRDCVGPGGGFGPVSDNGYGVAYMFPGNFRFFFHISCNKSSPET 375 PQQQ+ DL + V GGGFGPV+D+GYGV+Y+ G FHIS S PET Sbjct: 689 TPQQQVEL---FDLENNPEYVSSGGGFGPVADDGYGVSYILVGENLINFHISSKFSCPET 745 Query: 376 DSNKFGDMIYKSLYDIKALF 435 DS++FG + +++ DI LF Sbjct: 746 DSHRFGRHLKEAMTDIITLF 765
>sp|Q63704|CPT1B_RAT Carnitine O-palmitoyltransferase I, mitochondrial muscle isoform (CPT I) (CPTI-M) (Carnitine palmitoyltransferase 1B) (Carnitine palmitoyltransferase I-like protein) Length = 772 Score = 139 bits (349), Expect = 5e-33 Identities = 73/137 (53%), Positives = 94/137 (68%) Frame = +1 Query: 25 LFRRSCDMHQFLYREAMAGNGIDRHLFALFILSKGLGYDCEFLKDVLSSPWTLSTSQQPQ 204 LFR++ + HQ +YR AM G GIDRHLF L+I+SK LG FL +VLS PW+LSTSQ PQ Sbjct: 632 LFRKASEKHQNMYRLAMTGAGIDRHLFCLYIVSKYLGVRSPFLDEVLSEPWSLSTSQIPQ 691 Query: 205 QQINTGIDCDLPEYRDCVGPGGGFGPVSDNGYGVAYMFPGNFRFFFHISCNKSSPETDSN 384 QI D +Y + +G GGGFGPV+D+GYGV+YM G FFH+S SS ET++ Sbjct: 692 FQI---CMFDPKQYPNHLGAGGGFGPVADHGYGVSYMIAGENTMFFHVSSKLSSSETNAL 748 Query: 385 KFGDMIYKSLYDIKALF 435 +FG+ I ++L DI LF Sbjct: 749 RFGNHIRQALLDIADLF 765
>sp|Q8HY46|CPT1B_PIG Carnitine O-palmitoyltransferase I, mitochondrial muscle isoform (CPT I) (CPTI-M) (Carnitine palmitoyltransferase 1B) Length = 772 Score = 137 bits (345), Expect = 2e-32 Identities = 71/141 (50%), Positives = 93/141 (65%) Frame = +1 Query: 25 LFRRSCDMHQFLYREAMAGNGIDRHLFALFILSKGLGYDCEFLKDVLSSPWTLSTSQQPQ 204 LFR++ HQ +YR AM G GIDRHLF L+++SK LG FL +VLS PW LSTSQ Q Sbjct: 632 LFRKAAQKHQNMYRLAMTGAGIDRHLFCLYVVSKYLGVSSPFLAEVLSEPWRLSTSQIAQ 691 Query: 205 QQINTGIDCDLPEYRDCVGPGGGFGPVSDNGYGVAYMFPGNFRFFFHISCNKSSPETDSN 384 QI D +Y + +G GGGFGPV+D+GYGV+YM G FFH+S SS ET++ Sbjct: 692 FQIRM---FDPNKYPNHLGAGGGFGPVADDGYGVSYMIAGENTIFFHVSSKFSSSETNAQ 748 Query: 385 KFGDMIYKSLYDIKALFDGPQ 447 +FG+ I ++L D+ LF P+ Sbjct: 749 RFGNHIRQALLDLADLFQVPK 769
>sp|Q8BGD5|CPT1C_MOUSE Carnitine O-palmitoyltransferase I, mitochondrial brain isoform (Carnitine palmitoyltransferase 1C) (CPT IC) Length = 798 Score = 131 bits (329), Expect = 1e-30 Identities = 69/139 (49%), Positives = 87/139 (62%) Frame = +1 Query: 19 IRLFRRSCDMHQFLYREAMAGNGIDRHLFALFILSKGLGYDCEFLKDVLSSPWTLSTSQQ 198 + LFR + D HQ L + AM+G GIDRHLFAL+I+S+ L FL V S W LSTSQ Sbjct: 625 LALFRVAVDKHQALLKAAMSGQGIDRHLFALYIMSRLLHMQSPFLTQVQSQQWLLSTSQV 684 Query: 199 PQQQINTGIDCDLPEYRDCVGPGGGFGPVSDNGYGVAYMFPGNFRFFFHISCNKSSPETD 378 P QQ + D+ Y D V GGGFGP D+GYG++Y+F G FHIS KSS ETD Sbjct: 685 PVQQTHL---IDVHNYPDYVSSGGGFGPAHDHGYGISYIFMGENAITFHISSKKSSTETD 741 Query: 379 SNKFGDMIYKSLYDIKALF 435 S++ G I +L D+ +LF Sbjct: 742 SHRLGQHIENALLDVASLF 760
>sp|Q8TCG5|CPT1C_HUMAN Carnitine O-palmitoyltransferase I, mitochondrial brain isoform (Carnitine palmitoyltransferase 1C) (CPT IC) Length = 803 Score = 130 bits (328), Expect = 1e-30 Identities = 69/143 (48%), Positives = 90/143 (62%) Frame = +1 Query: 19 IRLFRRSCDMHQFLYREAMAGNGIDRHLFALFILSKGLGYDCEFLKDVLSSPWTLSTSQQ 198 + LFR + D HQ L + AM+G G+DRHLFAL+I+S+ L FL V S W LSTSQ Sbjct: 627 LALFRVAVDKHQALLKAAMSGQGVDRHLFALYIVSRFLHLQSPFLTQVHSEQWQLSTSQI 686 Query: 199 PQQQINTGIDCDLPEYRDCVGPGGGFGPVSDNGYGVAYMFPGNFRFFFHISCNKSSPETD 378 P QQ++ D+ Y D V GGGFGP D+GYGV+Y+F G+ FHIS KSS +TD Sbjct: 687 PVQQMHL---FDVHNYPDYVSSGGGFGPADDHGYGVSYIFMGDGMITFHISSKKSSTKTD 743 Query: 379 SNKFGDMIYKSLYDIKALFDGPQ 447 S++ G I +L D+ +LF Q Sbjct: 744 SHRLGQHIEDALLDVASLFQAGQ 766
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 63,568,849 Number of Sequences: 369166 Number of extensions: 1381499 Number of successful extensions: 4573 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 4076 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 4542 length of database: 68,354,980 effective HSP length: 103 effective length of database: 49,327,275 effective search space used: 3403581975 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)