Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_008_C10
(270 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P26268|ODPT_ASCSU Pyruvate dehydrogenase E1 component al... 106 2e-23
sp|P26267|ODPA_ASCSU Pyruvate dehydrogenase E1 component al... 101 6e-22
sp|P52899|ODPA_CAEEL Probable pyruvate dehydrogenase E1 com... 99 3e-21
sp|P26284|ODPA_RAT Pyruvate dehydrogenase E1 component alph... 92 3e-19
sp|P35486|ODPA_MOUSE Pyruvate dehydrogenase E1 component al... 92 3e-19
sp|P08559|ODPA_HUMAN Pyruvate dehydrogenase E1 component al... 92 3e-19
sp|P29804|ODPA_PIG Pyruvate dehydrogenase E1 component alph... 92 3e-19
sp|Q5R490|ODPA_PONPY Pyruvate dehydrogenase E1 component al... 92 3e-19
sp|Q8HXW9|ODPA_MACFA Pyruvate dehydrogenase E1 component al... 92 3e-19
sp|P29803|ODPAT_HUMAN Pyruvate dehydrogenase E1 component a... 90 1e-18
>sp|P26268|ODPT_ASCSU Pyruvate dehydrogenase E1 component alpha subunit type II,
mitochondrial precursor (PDHE1-A)
Length = 391
Score = 106 bits (264), Expect = 2e-23
Identities = 53/88 (60%), Positives = 62/88 (70%)
Frame = +1
Query: 7 ATFLLHSYKLHKLDSGPAHETTCTKADGLDMLKKMFQIRRMETVCGNLYKEKLIRGFCHL 186
ATF +KLHKLDSGP TK D L +M IRRMET GNLYKEK +RGFCHL
Sbjct: 25 ATFQAKPFKLHKLDSGPDVNMHVTKEDALRYYTQMQTIRRMETAAGNLYKEKKVRGFCHL 84
Query: 187 SSGQKAVAVGIEAALIPVDSIITSYRCH 270
SGQ+A AVG++AA+ P D+ IT+YRCH
Sbjct: 85 YSGQEACAVGMKAAMEPGDAAITAYRCH 112
>sp|P26267|ODPA_ASCSU Pyruvate dehydrogenase E1 component alpha subunit type I,
mitochondrial precursor (PDHE1-A)
Length = 396
Score = 101 bits (251), Expect = 6e-22
Identities = 49/88 (55%), Positives = 60/88 (68%)
Frame = +1
Query: 7 ATFLLHSYKLHKLDSGPAHETTCTKADGLDMLKKMFQIRRMETVCGNLYKEKLIRGFCHL 186
ATF +KLHKLDSGP TK D + +M IRRME+ GNLYKEK +RGFCHL
Sbjct: 30 ATFQTKPFKLHKLDSGPDINVHVTKEDAVHYYTQMLTIRRMESAAGNLYKEKKVRGFCHL 89
Query: 187 SSGQKAVAVGIEAALIPVDSIITSYRCH 270
SGQ+A AVG +AA+ D+ +T+YRCH
Sbjct: 90 YSGQEACAVGTKAAMDAGDAAVTAYRCH 117
>sp|P52899|ODPA_CAEEL Probable pyruvate dehydrogenase E1 component alpha subunit,
mitochondrial precursor (PDHE1-A)
Length = 397
Score = 99.0 bits (245), Expect = 3e-21
Identities = 47/80 (58%), Positives = 58/80 (72%)
Frame = +1
Query: 31 KLHKLDSGPAHETTCTKADGLDMLKKMFQIRRMETVCGNLYKEKLIRGFCHLSSGQKAVA 210
KLHKLD+GP T + D L + M IRRME+ GNLYKEK IRGFCHL SGQ+A A
Sbjct: 36 KLHKLDNGPNTSVTLNREDALKYYRDMQVIRRMESAAGNLYKEKKIRGFCHLYSGQEACA 95
Query: 211 VGIEAALIPVDSIITSYRCH 270
VG++AA+ D++IT+YRCH
Sbjct: 96 VGMKAAMTEGDAVITAYRCH 115
>sp|P26284|ODPA_RAT Pyruvate dehydrogenase E1 component alpha subunit, somatic form,
mitochondrial precursor (PDHE1-A type I)
Length = 390
Score = 92.4 bits (228), Expect = 3e-19
Identities = 43/90 (47%), Positives = 57/90 (63%)
Frame = +1
Query: 1 DSATFLLHSYKLHKLDSGPAHETTCTKADGLDMLKKMFQIRRMETVCGNLYKEKLIRGFC 180
+ ATF + LH+L+ GP T T+ DGL + M +RRME LYK+K+IRGFC
Sbjct: 32 NDATFEIKKCDLHRLEEGPPVTTVLTREDGLKYYRMMQTVRRMELKADQLYKQKIIRGFC 91
Query: 181 HLSSGQKAVAVGIEAALIPVDSIITSYRCH 270
HL GQ+A VG+EA + P D +IT+YR H
Sbjct: 92 HLCDGQEACCVGLEAGINPTDHLITAYRAH 121
>sp|P35486|ODPA_MOUSE Pyruvate dehydrogenase E1 component alpha subunit, somatic form,
mitochondrial precursor (PDHE1-A type I)
Length = 390
Score = 92.4 bits (228), Expect = 3e-19
Identities = 43/90 (47%), Positives = 57/90 (63%)
Frame = +1
Query: 1 DSATFLLHSYKLHKLDSGPAHETTCTKADGLDMLKKMFQIRRMETVCGNLYKEKLIRGFC 180
+ ATF + LH+L+ GP T T+ DGL + M +RRME LYK+K+IRGFC
Sbjct: 32 NDATFEIKKCDLHRLEEGPPVTTVLTREDGLKYYRMMQTVRRMELKADQLYKQKIIRGFC 91
Query: 181 HLSSGQKAVAVGIEAALIPVDSIITSYRCH 270
HL GQ+A VG+EA + P D +IT+YR H
Sbjct: 92 HLCDGQEACCVGLEAGINPTDHLITAYRAH 121
>sp|P08559|ODPA_HUMAN Pyruvate dehydrogenase E1 component alpha subunit, somatic form,
mitochondrial precursor (PDHE1-A type I)
Length = 390
Score = 92.4 bits (228), Expect = 3e-19
Identities = 43/90 (47%), Positives = 57/90 (63%)
Frame = +1
Query: 1 DSATFLLHSYKLHKLDSGPAHETTCTKADGLDMLKKMFQIRRMETVCGNLYKEKLIRGFC 180
+ ATF + LH+L+ GP T T+ DGL + M +RRME LYK+K+IRGFC
Sbjct: 32 NDATFEIKKCDLHRLEEGPPVTTVLTREDGLKYYRMMQTVRRMELKADQLYKQKIIRGFC 91
Query: 181 HLSSGQKAVAVGIEAALIPVDSIITSYRCH 270
HL GQ+A VG+EA + P D +IT+YR H
Sbjct: 92 HLCDGQEACCVGLEAGINPTDHLITAYRAH 121
>sp|P29804|ODPA_PIG Pyruvate dehydrogenase E1 component alpha subunit, somatic form,
mitochondrial precursor (PDHE1-A type I)
Length = 389
Score = 92.4 bits (228), Expect = 3e-19
Identities = 43/90 (47%), Positives = 57/90 (63%)
Frame = +1
Query: 1 DSATFLLHSYKLHKLDSGPAHETTCTKADGLDMLKKMFQIRRMETVCGNLYKEKLIRGFC 180
+ ATF + LH+L+ GP T T+ DGL + M +RRME LYK+K+IRGFC
Sbjct: 31 NDATFEIKKCDLHRLEEGPPVTTVLTREDGLKYYRMMQTVRRMELKADQLYKQKIIRGFC 90
Query: 181 HLSSGQKAVAVGIEAALIPVDSIITSYRCH 270
HL GQ+A VG+EA + P D +IT+YR H
Sbjct: 91 HLCDGQEACCVGLEAGINPTDHLITAYRAH 120
>sp|Q5R490|ODPA_PONPY Pyruvate dehydrogenase E1 component alpha subunit, somatic form,
mitochondrial precursor (PDHE1-A type I)
Length = 390
Score = 92.4 bits (228), Expect = 3e-19
Identities = 43/90 (47%), Positives = 57/90 (63%)
Frame = +1
Query: 1 DSATFLLHSYKLHKLDSGPAHETTCTKADGLDMLKKMFQIRRMETVCGNLYKEKLIRGFC 180
+ ATF + LH+L+ GP T T+ DGL + M +RRME LYK+K+IRGFC
Sbjct: 32 NDATFEIKKCDLHRLEEGPPVTTVLTREDGLKYYRMMQTVRRMELKADQLYKQKIIRGFC 91
Query: 181 HLSSGQKAVAVGIEAALIPVDSIITSYRCH 270
HL GQ+A VG+EA + P D +IT+YR H
Sbjct: 92 HLCDGQEACCVGLEAGINPTDHLITAYRAH 121
>sp|Q8HXW9|ODPA_MACFA Pyruvate dehydrogenase E1 component alpha subunit, somatic form,
mitochondrial precursor (PDHE1-A type I)
Length = 390
Score = 92.4 bits (228), Expect = 3e-19
Identities = 43/90 (47%), Positives = 57/90 (63%)
Frame = +1
Query: 1 DSATFLLHSYKLHKLDSGPAHETTCTKADGLDMLKKMFQIRRMETVCGNLYKEKLIRGFC 180
+ ATF + LH+L+ GP T T+ DGL + M +RRME LYK+K+IRGFC
Sbjct: 32 NDATFEIKKCDLHRLEEGPPVTTVLTREDGLKYYRMMQTVRRMELKADQLYKQKIIRGFC 91
Query: 181 HLSSGQKAVAVGIEAALIPVDSIITSYRCH 270
HL GQ+A VG+EA + P D +IT+YR H
Sbjct: 92 HLCDGQEACCVGLEAGINPTDHLITAYRAH 121
>sp|P29803|ODPAT_HUMAN Pyruvate dehydrogenase E1 component alpha subunit, testis-specific
form, mitochondrial precursor (PDHE1-A type II)
Length = 388
Score = 90.1 bits (222), Expect = 1e-18
Identities = 43/90 (47%), Positives = 56/90 (62%)
Frame = +1
Query: 1 DSATFLLHSYKLHKLDSGPAHETTCTKADGLDMLKKMFQIRRMETVCGNLYKEKLIRGFC 180
+ ATF + L+ L+ GP T T+A+GL + M +RRME LYK+K IRGFC
Sbjct: 30 NDATFEIKKCDLYLLEEGPPVTTVLTRAEGLKYYRMMLTVRRMELKADQLYKQKFIRGFC 89
Query: 181 HLSSGQKAVAVGIEAALIPVDSIITSYRCH 270
HL GQ+A VG+EA + P D +ITSYR H
Sbjct: 90 HLCDGQEACCVGLEAGINPSDHVITSYRAH 119
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 29,557,534
Number of Sequences: 369166
Number of extensions: 473482
Number of successful extensions: 948
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 943
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 948
length of database: 68,354,980
effective HSP length: 59
effective length of database: 57,455,615
effective search space used: 1723668450
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)