Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_008_A24
(304 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9D7W4|TSN17_MOUSE Tetraspanin-17 (Tspan-17) (Transmembr... 89 2e-18
sp|Q96FV3|TSN17_HUMAN Tetraspanin-17 (Tspan-17) (Transmembr... 87 2e-17
sp|Q8NG11|TSN14_HUMAN Tetraspanin-14 (Tspan-14) (Transmembr... 82 3e-16
sp|Q8QZY6|TSN14_MOUSE Tetraspanin-14 (Tspan-14) (Transmembr... 81 7e-16
sp|P62080|TSN5_MOUSE Tetraspanin-5 (Tspan-5) (Transmembrane... 80 1e-15
sp|Q68VK5|TSN5_RAT Tetraspanin-5 (Tspan-5) (Transmembrane 4... 80 1e-15
sp|Q9H1Z9|TSN10_HUMAN Tetraspanin-10 (Tspan-10) (Oculospanin) 65 5e-11
sp|Q8VCF5|TSN10_MOUSE Tetraspanin-10 (Tspan-10) (Oculospanin) 63 2e-10
sp|O95858|TSN15_HUMAN Tetraspanin-15 (Tspan-15) (Transmembr... 60 2e-09
sp|Q80WR1|TSN18_MOUSE Tetraspanin-18 (Tspan-18) 35 0.054
>sp|Q9D7W4|TSN17_MOUSE Tetraspanin-17 (Tspan-17) (Transmembrane 4 superfamily member 17)
(Tetraspan protein SB134) (F-box only protein 23)
Length = 270
Score = 89.4 bits (220), Expect = 2e-18
Identities = 42/91 (46%), Positives = 59/91 (64%), Gaps = 2/91 (2%)
Frame = +2
Query: 26 YRENVDLRDLFEWVQEIWLLCCGIDGPNDWDMNMYFNCS--SPSAEKCAVPPSCCRTTPK 199
YR+++DL++L ++ QE W CCG GPNDW++N+YFNC+ +PS E+C VP SCC P
Sbjct: 136 YRDDLDLQNLIDFAQEYWS-CCGARGPNDWNLNIYFNCTDLNPSRERCGVPFSCCVRDPA 194
Query: 200 NNIRNLLCGRMIRDNSMAKSRNEKIYTIGCV 292
++ N CG IR + + IYT GCV
Sbjct: 195 EDVLNTQCGYDIR-LKLELEQEGSIYTKGCV 224
>sp|Q96FV3|TSN17_HUMAN Tetraspanin-17 (Tspan-17) (Transmembrane 4 superfamily member 17)
(Tetraspan protein SB134) (F-box only protein 23)
Length = 263
Score = 86.7 bits (213), Expect = 2e-17
Identities = 40/91 (43%), Positives = 59/91 (64%), Gaps = 2/91 (2%)
Frame = +2
Query: 26 YRENVDLRDLFEWVQEIWLLCCGIDGPNDWDMNMYFNCS--SPSAEKCAVPPSCCRTTPK 199
YR+++DL++L ++ QE W CCG GPNDW++N+YFNC+ +PS E+C VP SCC P
Sbjct: 136 YRDDIDLQNLIDFAQEYWS-CCGARGPNDWNLNIYFNCTDLNPSRERCGVPFSCCVRDPA 194
Query: 200 NNIRNLLCGRMIRDNSMAKSRNEKIYTIGCV 292
++ N CG +R + + I+T GCV
Sbjct: 195 EDVLNTQCGYDVR-LKLELEQQGFIHTKGCV 224
>sp|Q8NG11|TSN14_HUMAN Tetraspanin-14 (Tspan-14) (Transmembrane 4 superfamily member 14)
(DC-TM4F2)
Length = 270
Score = 82.4 bits (202), Expect = 3e-16
Identities = 42/94 (44%), Positives = 59/94 (62%), Gaps = 2/94 (2%)
Frame = +2
Query: 23 NYRENVDLRDLFEWVQEIWLLCCGIDGPNDWDMNMYFNCS--SPSAEKCAVPPSCCRTTP 196
+YR+++DL++L + +Q+ CCG GP DWD+N+YFNCS S S EKC VP SCC P
Sbjct: 133 SYRDDIDLQNLIDSLQKA-NQCCGAYGPEDWDLNVYFNCSGASYSREKCGVPFSCCVPDP 191
Query: 197 KNNIRNLLCGRMIRDNSMAKSRNEKIYTIGCVYA 298
+ N CG +R +K +E I+T GC+ A
Sbjct: 192 AQKVVNTQCGYDVRIQLKSK-WDESIFTKGCIQA 224
>sp|Q8QZY6|TSN14_MOUSE Tetraspanin-14 (Tspan-14) (Transmembrane 4 superfamily member 14)
Length = 270
Score = 81.3 bits (199), Expect = 7e-16
Identities = 42/94 (44%), Positives = 59/94 (62%), Gaps = 2/94 (2%)
Frame = +2
Query: 23 NYRENVDLRDLFEWVQEIWLLCCGIDGPNDWDMNMYFNCS--SPSAEKCAVPPSCCRTTP 196
+YR+++DL++L + +Q+ CCG GP DWD+N+YFNCS S S EKC VP SCC P
Sbjct: 133 SYRDDIDLQNLIDSLQKA-NQCCGAYGPEDWDLNVYFNCSGASYSREKCGVPFSCCVPDP 191
Query: 197 KNNIRNLLCGRMIRDNSMAKSRNEKIYTIGCVYA 298
+ N CG +R +K +E I+T GC+ A
Sbjct: 192 AQKVVNTQCGYDVRIQLKSK-WDEFIFTKGCIQA 224
>sp|P62080|TSN5_MOUSE Tetraspanin-5 (Tspan-5) (Transmembrane 4 superfamily member 9)
(Tetraspan NET-4)
sp|P62079|TSN5_HUMAN Tetraspanin-5 (Tspan-5) (Transmembrane 4 superfamily member 9)
(Tetraspan NET-4)
Length = 268
Score = 80.5 bits (197), Expect = 1e-15
Identities = 39/91 (42%), Positives = 55/91 (60%), Gaps = 2/91 (2%)
Frame = +2
Query: 26 YRENVDLRDLFEWVQEIWLLCCGIDGPNDWDMNMYFNC--SSPSAEKCAVPPSCCRTTPK 199
YR+++DL++L ++ QE W CCG G +DW++N+YFNC S+ S E+C VP SCC P
Sbjct: 134 YRDDIDLQNLIDFTQEYWQ-CCGAFGADDWNLNIYFNCTDSNASRERCGVPFSCCTKDPA 192
Query: 200 NNIRNLLCGRMIRDNSMAKSRNEKIYTIGCV 292
++ N CG R + IYT GCV
Sbjct: 193 EDVINTQCGYDARQKPEV-DQQIVIYTKGCV 222
>sp|Q68VK5|TSN5_RAT Tetraspanin-5 (Tspan-5) (Transmembrane 4 superfamily member 9)
Length = 268
Score = 80.1 bits (196), Expect = 1e-15
Identities = 39/91 (42%), Positives = 54/91 (59%), Gaps = 2/91 (2%)
Frame = +2
Query: 26 YRENVDLRDLFEWVQEIWLLCCGIDGPNDWDMNMYFNC--SSPSAEKCAVPPSCCRTTPK 199
YR+++DL+ L ++ QE W CCG G +DW++N+YFNC S+ S E+C VP SCC P
Sbjct: 134 YRDDIDLQSLIDFTQEYWQ-CCGAFGADDWNLNIYFNCTDSNASRERCGVPFSCCTKDPA 192
Query: 200 NNIRNLLCGRMIRDNSMAKSRNEKIYTIGCV 292
++ N CG R + IYT GCV
Sbjct: 193 EDVINTQCGYDARQKPEV-DQQIVIYTKGCV 222
>sp|Q9H1Z9|TSN10_HUMAN Tetraspanin-10 (Tspan-10) (Oculospanin)
Length = 355
Score = 65.1 bits (157), Expect = 5e-11
Identities = 27/60 (45%), Positives = 39/60 (65%)
Frame = +2
Query: 5 LKTILINYRENVDLRDLFEWVQEIWLLCCGIDGPNDWDMNMYFNCSSPSAEKCAVPPSCC 184
L+ + +Y+++ DLR L + VQ + L CCG DW N+YFNCSSP + C++P SCC
Sbjct: 186 LRVAIAHYQDDPDLRFLLDQVQ-LGLRCCGAASYQDWQQNLYFNCSSPGVQACSLPASCC 244
>sp|Q8VCF5|TSN10_MOUSE Tetraspanin-10 (Tspan-10) (Oculospanin)
Length = 331
Score = 63.2 bits (152), Expect = 2e-10
Identities = 30/75 (40%), Positives = 43/75 (57%), Gaps = 1/75 (1%)
Frame = +2
Query: 5 LKTILINYRENVDLRDLFEWVQEIWLLCCGIDGPNDWDMNMYFNCSSPSAEKCAVPPSCC 184
L +I+Y ++ DL L + VQ + L CCG DW N+YFNCSSP + C++P SCC
Sbjct: 184 LHAAIIHYWDDPDLHFLLDQVQ-LGLQCCGAVSYQDWQQNLYFNCSSPGVQACSLPASCC 242
Query: 185 RTTPKNN-IRNLLCG 226
++ + N CG
Sbjct: 243 INPQEDGAVVNTQCG 257
>sp|O95858|TSN15_HUMAN Tetraspanin-15 (Tspan-15) (Transmembrane 4 superfamily member 15)
(Tetraspan NET-7)
Length = 294
Score = 59.7 bits (143), Expect = 2e-09
Identities = 33/100 (33%), Positives = 53/100 (53%), Gaps = 1/100 (1%)
Frame = +2
Query: 2 NLKTILINYRENVDLRDLFEWVQEIWLLCCGIDGPNDWDMNMYFNCSSPSAEKCAVPPSC 181
N++ + NY +++D +++ ++VQ+ + CCG + DW N Y +CS+P C VP +C
Sbjct: 127 NIRRGIENYYDDLDFKNIMDFVQKKFK-CCGGEDYRDWSKNQYHDCSAPGPLACGVPYTC 185
Query: 182 C-RTTPKNNIRNLLCGRMIRDNSMAKSRNEKIYTIGCVYA 298
C R T + N +CG D S + IY GC A
Sbjct: 186 CIRNT--TEVVNTMCGYKTIDKERF-SVQDVIYVRGCTNA 222
>sp|Q80WR1|TSN18_MOUSE Tetraspanin-18 (Tspan-18)
Length = 248
Score = 35.0 bits (79), Expect = 0.054
Identities = 14/38 (36%), Positives = 22/38 (57%)
Frame = +2
Query: 86 CCGIDGPNDWDMNMYFNCSSPSAEKCAVPPSCCRTTPK 199
CCG++GP D+ + F + E+ VP +CCR P+
Sbjct: 147 CCGVNGPEDFKLASVFRLLTLDTEE--VPKACCRREPQ 182
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 37,794,903
Number of Sequences: 369166
Number of extensions: 714053
Number of successful extensions: 1731
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 1672
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 1709
length of database: 68,354,980
effective HSP length: 69
effective length of database: 55,608,265
effective search space used: 1723856215
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)