Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_008_A11
(379 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9BQ16|TICN3_HUMAN Testican-3 precursor (SPARC/osteonect... 42 6e-04
sp|Q5RD69|TICN3_PONPY Testican-3 precursor (SPARC/osteonect... 42 6e-04
sp|Q8BKV0|TICN3_MOUSE Testican-3 precursor (SPARC/osteonect... 41 7e-04
sp|O88322|NID2_MOUSE Nidogen-2 precursor (NID-2) (Entactin-2) 40 0.001
sp|Q14112|NID2_HUMAN Nidogen-2 precursor (NID-2) (Osteonido... 39 0.004
sp|P06882|THYG_RAT Thyroglobulin precursor 39 0.005
sp|O08710|THYG_MOUSE Thyroglobulin precursor 39 0.005
sp|Q62288|TICN1_MOUSE Testican-1 precursor (SPOCK protein) 38 0.008
sp|Q08629|TICN1_HUMAN Testican-1 precursor (SPOCK protein) 38 0.008
sp|P01266|THYG_HUMAN Thyroglobulin precursor 38 0.008
>sp|Q9BQ16|TICN3_HUMAN Testican-3 precursor (SPARC/osteonectin, CWCV, and Kazal-like
domains proteoglycan 3)
Length = 436
Score = 41.6 bits (96), Expect = 6e-04
Identities = 16/31 (51%), Positives = 21/31 (67%), Gaps = 2/31 (6%)
Frame = +2
Query: 38 CEDTGMYKPVQCVGAA--CWCVDDSGDEIKG 124
C++ G YKP QC G+ CWCVD G+E+ G
Sbjct: 341 CDEDGYYKPTQCHGSVGQCWCVDRYGNEVMG 371
>sp|Q5RD69|TICN3_PONPY Testican-3 precursor (SPARC/osteonectin, CWCV, and Kazal-like
domains proteoglycan 3)
Length = 436
Score = 41.6 bits (96), Expect = 6e-04
Identities = 16/31 (51%), Positives = 21/31 (67%), Gaps = 2/31 (6%)
Frame = +2
Query: 38 CEDTGMYKPVQCVGAA--CWCVDDSGDEIKG 124
C++ G YKP QC G+ CWCVD G+E+ G
Sbjct: 341 CDEDGYYKPTQCHGSVGQCWCVDRYGNEVMG 371
>sp|Q8BKV0|TICN3_MOUSE Testican-3 precursor (SPARC/osteonectin, CWCV, and Kazal-like
domains proteoglycan 3)
Length = 436
Score = 41.2 bits (95), Expect = 7e-04
Identities = 16/31 (51%), Positives = 21/31 (67%), Gaps = 2/31 (6%)
Frame = +2
Query: 38 CEDTGMYKPVQCVGAA--CWCVDDSGDEIKG 124
C++ G YKP QC G+ CWCVD G+E+ G
Sbjct: 341 CDEDGYYKPTQCHGSVGQCWCVDRYGNEVVG 371
>sp|O88322|NID2_MOUSE Nidogen-2 precursor (NID-2) (Entactin-2)
Length = 1403
Score = 40.4 bits (93), Expect = 0.001
Identities = 16/35 (45%), Positives = 22/35 (62%), Gaps = 2/35 (5%)
Frame = +2
Query: 26 HFHFCEDTGMYKPVQCVGAA--CWCVDDSGDEIKG 124
H C+D G + P+QC G+ CWCVD +G E+ G
Sbjct: 987 HIPQCDDQGNFVPLQCHGSTGFCWCVDRNGHEVPG 1021
Score = 38.5 bits (88), Expect = 0.005
Identities = 15/31 (48%), Positives = 21/31 (67%), Gaps = 2/31 (6%)
Frame = +2
Query: 38 CEDTGMYKPVQCVGAA--CWCVDDSGDEIKG 124
C+D G + P+QC G + CWCVD G E++G
Sbjct: 1071 CDDLGHFIPLQCHGKSDFCWCVDKDGRELQG 1101
>sp|Q14112|NID2_HUMAN Nidogen-2 precursor (NID-2) (Osteonidogen)
Length = 1375
Score = 38.9 bits (89), Expect = 0.004
Identities = 15/35 (42%), Positives = 21/35 (60%), Gaps = 2/35 (5%)
Frame = +2
Query: 26 HFHFCEDTGMYKPVQCVGAA--CWCVDDSGDEIKG 124
H C++ G + P+QC G+ CWCVD G E+ G
Sbjct: 959 HIPQCDEQGNFLPLQCHGSTGFCWCVDPDGHEVPG 993
Score = 38.9 bits (89), Expect = 0.004
Identities = 15/31 (48%), Positives = 21/31 (67%), Gaps = 2/31 (6%)
Frame = +2
Query: 38 CEDTGMYKPVQCVGAA--CWCVDDSGDEIKG 124
C+D G + P+QC G + CWCVD G E++G
Sbjct: 1043 CDDLGHFIPLQCHGKSDFCWCVDKDGREVQG 1073
>sp|P06882|THYG_RAT Thyroglobulin precursor
Length = 2768
Score = 38.5 bits (88), Expect = 0.005
Identities = 16/31 (51%), Positives = 19/31 (61%), Gaps = 2/31 (6%)
Frame = +2
Query: 38 CEDTGMYKPVQC--VGAACWCVDDSGDEIKG 124
C+D+G Y PVQC CWCVD G E+ G
Sbjct: 121 CQDSGNYAPVQCDLQQVQCWCVDTEGMEVYG 151
Score = 37.7 bits (86), Expect = 0.008
Identities = 12/29 (41%), Positives = 17/29 (58%)
Frame = +2
Query: 38 CEDTGMYKPVQCVGAACWCVDDSGDEIKG 124
C G Y+ +QC CWCV+ G E++G
Sbjct: 620 CTAEGSYEDIQCYAGECWCVNSQGKEVEG 648
Score = 37.0 bits (84), Expect = 0.014
Identities = 14/31 (45%), Positives = 19/31 (61%), Gaps = 2/31 (6%)
Frame = +2
Query: 38 CEDTGMYKPVQCV--GAACWCVDDSGDEIKG 124
C + G ++ VQC G +CWCVD G E+ G
Sbjct: 53 CSEDGSFQTVQCQNDGQSCWCVDSDGTEVPG 83
Score = 36.2 bits (82), Expect = 0.024
Identities = 20/49 (40%), Positives = 25/49 (51%), Gaps = 1/49 (2%)
Frame = +2
Query: 38 CEDTGMYKPVQC-VGAACWCVDDSGDEIKGYITGIEKFYGKTCKCAKDK 181
C G Y+ VQC + CWCVD G EI G + G+ CAKD+
Sbjct: 320 CHRDGHYQTVQCQMERMCWCVDAQGIEIPG-----TRQQGQPLFCAKDQ 363
Score = 34.7 bits (78), Expect = 0.070
Identities = 13/29 (44%), Positives = 16/29 (55%)
Frame = +2
Query: 38 CEDTGMYKPVQCVGAACWCVDDSGDEIKG 124
C G + PVQC + C+CVD G I G
Sbjct: 687 CTSEGYFLPVQCFNSECYCVDAEGQVIPG 715
Score = 31.2 bits (69), Expect = 0.77
Identities = 14/31 (45%), Positives = 17/31 (54%), Gaps = 2/31 (6%)
Frame = +2
Query: 38 CEDTGMYKPVQCVGAA--CWCVDDSGDEIKG 124
C G ++PVQC CWCVD G+ I G
Sbjct: 1032 CNTIGGWEPVQCHPGTGQCWCVDGWGELIPG 1062
Score = 31.2 bits (69), Expect = 0.77
Identities = 13/27 (48%), Positives = 17/27 (62%), Gaps = 2/27 (7%)
Frame = +2
Query: 50 GMYKPVQC--VGAACWCVDDSGDEIKG 124
G + PVQC +CWCV SG+E+ G
Sbjct: 1175 GGFSPVQCDLAQGSCWCVLASGEEVPG 1201
Score = 28.1 bits (61), Expect = 6.5
Identities = 8/14 (57%), Positives = 12/14 (85%)
Frame = +2
Query: 83 ACWCVDDSGDEIKG 124
+CWCVD++G E+ G
Sbjct: 898 SCWCVDEAGQELDG 911
>sp|O08710|THYG_MOUSE Thyroglobulin precursor
Length = 2766
Score = 38.5 bits (88), Expect = 0.005
Identities = 16/31 (51%), Positives = 19/31 (61%), Gaps = 2/31 (6%)
Frame = +2
Query: 38 CEDTGMYKPVQC--VGAACWCVDDSGDEIKG 124
C+D+G Y PVQC CWCVD G E+ G
Sbjct: 121 CQDSGNYAPVQCDLQRVQCWCVDTEGMEVYG 151
Score = 37.7 bits (86), Expect = 0.008
Identities = 13/29 (44%), Positives = 16/29 (55%)
Frame = +2
Query: 38 CEDTGMYKPVQCVGAACWCVDDSGDEIKG 124
C G Y+ +QC CWCVD G E+ G
Sbjct: 620 CTAGGSYEDIQCYAGECWCVDSRGKELDG 648
Score = 36.6 bits (83), Expect = 0.018
Identities = 14/31 (45%), Positives = 19/31 (61%), Gaps = 2/31 (6%)
Frame = +2
Query: 38 CEDTGMYKPVQCV--GAACWCVDDSGDEIKG 124
C + G ++ VQC G +CWCVD G E+ G
Sbjct: 53 CSEDGSFQTVQCQNDGQSCWCVDSDGREVPG 83
Score = 34.3 bits (77), Expect = 0.091
Identities = 18/49 (36%), Positives = 23/49 (46%), Gaps = 1/49 (2%)
Frame = +2
Query: 38 CEDTGMYKPVQC-VGAACWCVDDSGDEIKGYITGIEKFYGKTCKCAKDK 181
C G Y+ VQC CWCVD G E+ G + G+ CA D+
Sbjct: 320 CHRDGHYQTVQCQTEGMCWCVDAQGREVPG-----TRQQGQPPSCAADQ 363
Score = 34.3 bits (77), Expect = 0.091
Identities = 13/29 (44%), Positives = 16/29 (55%)
Frame = +2
Query: 38 CEDTGMYKPVQCVGAACWCVDDSGDEIKG 124
C G + PVQC + C+CVD G I G
Sbjct: 687 CTREGYFLPVQCFNSECYCVDTEGQVIPG 715
Score = 32.3 bits (72), Expect = 0.35
Identities = 13/27 (48%), Positives = 17/27 (62%), Gaps = 2/27 (7%)
Frame = +2
Query: 50 GMYKPVQC--VGAACWCVDDSGDEIKG 124
G + PVQC +CWCV SG+E+ G
Sbjct: 1175 GAFSPVQCDLAQGSCWCVLGSGEEVPG 1201
Score = 32.0 bits (71), Expect = 0.45
Identities = 14/31 (45%), Positives = 17/31 (54%), Gaps = 2/31 (6%)
Frame = +2
Query: 38 CEDTGMYKPVQCVGAA--CWCVDDSGDEIKG 124
C G ++PVQC CWCVD G+ I G
Sbjct: 1032 CNMIGGWEPVQCHAGTGQCWCVDGRGEFIPG 1062
>sp|Q62288|TICN1_MOUSE Testican-1 precursor (SPOCK protein)
Length = 442
Score = 37.7 bits (86), Expect = 0.008
Identities = 15/31 (48%), Positives = 19/31 (61%), Gaps = 2/31 (6%)
Frame = +2
Query: 38 CEDTGMYKPVQCVGAA--CWCVDDSGDEIKG 124
C + G YK QC G+ CWCVD G+E+ G
Sbjct: 340 CNEEGYYKATQCHGSTGQCWCVDKYGNELAG 370
>sp|Q08629|TICN1_HUMAN Testican-1 precursor (SPOCK protein)
Length = 439
Score = 37.7 bits (86), Expect = 0.008
Identities = 15/31 (48%), Positives = 19/31 (61%), Gaps = 2/31 (6%)
Frame = +2
Query: 38 CEDTGMYKPVQCVGAA--CWCVDDSGDEIKG 124
C + G YK QC G+ CWCVD G+E+ G
Sbjct: 337 CNEEGYYKATQCHGSTGQCWCVDKYGNELAG 367
>sp|P01266|THYG_HUMAN Thyroglobulin precursor
Length = 2768
Score = 37.7 bits (86), Expect = 0.008
Identities = 16/31 (51%), Positives = 19/31 (61%), Gaps = 2/31 (6%)
Frame = +2
Query: 38 CEDTGMYKPVQC--VGAACWCVDDSGDEIKG 124
C+D+G Y PVQC CWCVD G E+ G
Sbjct: 120 CQDSGDYAPVQCDVQQVQCWCVDAEGMEVYG 150
Score = 37.0 bits (84), Expect = 0.014
Identities = 18/44 (40%), Positives = 22/44 (50%)
Frame = +2
Query: 38 CEDTGMYKPVQCVGAACWCVDDSGDEIKGYITGIEKFYGKTCKC 169
C G + PVQC + C+CVD G I G + I GK KC
Sbjct: 687 CTSEGHFLPVQCFNSECYCVDAEGQAIPGTRSAI----GKPKKC 726
Score = 36.2 bits (82), Expect = 0.024
Identities = 13/29 (44%), Positives = 16/29 (55%)
Frame = +2
Query: 38 CEDTGMYKPVQCVGAACWCVDDSGDEIKG 124
C G Y+ VQC CWCV+ G E+ G
Sbjct: 620 CTTEGSYEDVQCFSGECWCVNSWGKELPG 648
Score = 35.8 bits (81), Expect = 0.031
Identities = 15/34 (44%), Positives = 20/34 (58%), Gaps = 2/34 (5%)
Frame = +2
Query: 38 CEDTGMYKPVQCVGAA--CWCVDDSGDEIKGYIT 133
C+ G ++PVQC CWCVD+ G I G +T
Sbjct: 1031 CDAFGSWEPVQCHAGTGHCWCVDEKGGFIPGSLT 1064
Score = 35.4 bits (80), Expect = 0.041
Identities = 15/29 (51%), Positives = 20/29 (68%), Gaps = 2/29 (6%)
Frame = +2
Query: 44 DTGMYKPVQCVGA--ACWCVDDSGDEIKG 124
+ G + PVQC A +CWCV DSG+E+ G
Sbjct: 1172 EDGGFSPVQCDQAQGSCWCVMDSGEEVPG 1200
Score = 33.5 bits (75), Expect = 0.16
Identities = 13/31 (41%), Positives = 19/31 (61%), Gaps = 2/31 (6%)
Frame = +2
Query: 38 CEDTGMYKPVQCV--GAACWCVDDSGDEIKG 124
C + G ++ VQC G +CWCV +G E+ G
Sbjct: 52 CAEDGSFQTVQCQNDGRSCWCVGANGSEVLG 82
Score = 32.7 bits (73), Expect = 0.26
Identities = 14/30 (46%), Positives = 16/30 (53%), Gaps = 1/30 (3%)
Frame = +2
Query: 38 CEDTGMYKPVQC-VGAACWCVDDSGDEIKG 124
C G Y+ VQC CWCVD G E+ G
Sbjct: 319 CRRNGDYQAVQCQTEGPCWCVDAQGKEMHG 348
Score = 32.3 bits (72), Expect = 0.35
Identities = 14/29 (48%), Positives = 19/29 (65%), Gaps = 1/29 (3%)
Frame = +2
Query: 38 CEDTGMYKPVQCVGAACWCVDD-SGDEIK 121
C +TG Y +Q GA WCVD SG+E++
Sbjct: 1108 CLETGEYARLQASGAGTWCVDPASGEELR 1136
Score = 28.5 bits (62), Expect = 5.0
Identities = 8/13 (61%), Positives = 12/13 (92%)
Frame = +2
Query: 86 CWCVDDSGDEIKG 124
CWCVD++G E++G
Sbjct: 898 CWCVDEAGQELEG 910
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 48,238,756
Number of Sequences: 369166
Number of extensions: 967421
Number of successful extensions: 2635
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2512
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2608
length of database: 68,354,980
effective HSP length: 92
effective length of database: 51,359,360
effective search space used: 1694858880
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)