Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_007_O16
(645 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|O35286|DHX15_MOUSE Putative pre-mRNA splicing factor RNA... 344 1e-94
sp|O43143|DHX15_HUMAN Putative pre-mRNA splicing factor RNA... 344 1e-94
sp|Q20875|DHX15_CAEEL Putative pre-mRNA splicing factor ATP... 321 1e-87
sp|O22899|DHX15_ARATH Putative pre-mRNA splicing factor ATP... 313 2e-85
sp|P53131|PRP43_YEAST Pre-mRNA splicing factor RNA helicase... 240 3e-63
sp|O42945|DHX15_SCHPO Probable pre-mRNA splicing factor RNA... 226 3e-59
sp|O17438|DHX15_STRPU Putative pre-mRNA splicing factor ATP... 162 7e-40
sp|Q14562|DHX8_HUMAN ATP-dependent helicase DHX8 (RNA helic... 152 9e-37
sp|O60231|DHX16_HUMAN Putative pre-mRNA splicing factor RNA... 150 2e-36
sp|Q7YR39|DHX16_PANTR Putative pre-mRNA splicing factor RNA... 150 2e-36
>sp|O35286|DHX15_MOUSE Putative pre-mRNA splicing factor RNA helicase (DEAH box protein 15)
Length = 795
Score = 344 bits (883), Expect = 1e-94
Identities = 159/199 (79%), Positives = 181/199 (90%)
Frame = +2
Query: 2 TAMLSVPQCFVRPTEARTAADEAKMGFAHIDGDHLTMLNVYHAFKQNREDSQWCYEHFVN 181
TAMLSVPQCFVRPTEA+ AADEAKM FAHIDGDHLT+LNVYHAFKQN E QWCY++F+N
Sbjct: 591 TAMLSVPQCFVRPTEAKKAADEAKMRFAHIDGDHLTLLNVYHAFKQNHESVQWCYDNFIN 650
Query: 182 YRSLKAADNVRIQLSRIMDRFNLRRSSTDFSSKDYYVNIRKALVSGFFMQVAHLERSGHY 361
YRSL +ADNVR QLSRIMDRFNL R STDF+S+DYY+NIRKALV+G+FMQVAHLER+GHY
Sbjct: 651 YRSLMSADNVRQQLSRIMDRFNLPRRSTDFTSRDYYINIRKALVTGYFMQVAHLERTGHY 710
Query: 362 LTVKDNQIVHLHPSTCLDHKPEWVLYNEFVLTTKNFIRTVCEVKPEWLVKVAPQYYDMSN 541
LTVKDNQ+V LHPST LDHKPEWVLYNEFVLTTKN+IRT ++KPEWLVK+APQYYDMSN
Sbjct: 711 LTVKDNQVVQLHPSTVLDHKPEWVLYNEFVLTTKNYIRTCTDIKPEWLVKIAPQYYDMSN 770
Query: 542 FPPCAAKEIIERIINRMQN 598
FP C AK ++RII ++Q+
Sbjct: 771 FPQCEAKRQLDRIIAKLQS 789
>sp|O43143|DHX15_HUMAN Putative pre-mRNA splicing factor RNA helicase (DEAH box protein 15)
(ATP-dependent RNA helicase #46)
Length = 795
Score = 344 bits (883), Expect = 1e-94
Identities = 159/199 (79%), Positives = 181/199 (90%)
Frame = +2
Query: 2 TAMLSVPQCFVRPTEARTAADEAKMGFAHIDGDHLTMLNVYHAFKQNREDSQWCYEHFVN 181
TAMLSVPQCFVRPTEA+ AADEAKM FAHIDGDHLT+LNVYHAFKQN E QWCY++F+N
Sbjct: 591 TAMLSVPQCFVRPTEAKKAADEAKMRFAHIDGDHLTLLNVYHAFKQNHESVQWCYDNFIN 650
Query: 182 YRSLKAADNVRIQLSRIMDRFNLRRSSTDFSSKDYYVNIRKALVSGFFMQVAHLERSGHY 361
YRSL +ADNVR QLSRIMDRFNL R STDF+S+DYY+NIRKALV+G+FMQVAHLER+GHY
Sbjct: 651 YRSLMSADNVRQQLSRIMDRFNLPRRSTDFTSRDYYINIRKALVTGYFMQVAHLERTGHY 710
Query: 362 LTVKDNQIVHLHPSTCLDHKPEWVLYNEFVLTTKNFIRTVCEVKPEWLVKVAPQYYDMSN 541
LTVKDNQ+V LHPST LDHKPEWVLYNEFVLTTKN+IRT ++KPEWLVK+APQYYDMSN
Sbjct: 711 LTVKDNQVVQLHPSTVLDHKPEWVLYNEFVLTTKNYIRTCTDIKPEWLVKIAPQYYDMSN 770
Query: 542 FPPCAAKEIIERIINRMQN 598
FP C AK ++RII ++Q+
Sbjct: 771 FPQCEAKRQLDRIIAKLQS 789
>sp|Q20875|DHX15_CAEEL Putative pre-mRNA splicing factor ATP-dependent RNA helicase F56D2.6
Length = 739
Score = 321 bits (822), Expect = 1e-87
Identities = 145/198 (73%), Positives = 173/198 (87%)
Frame = +2
Query: 2 TAMLSVPQCFVRPTEARTAADEAKMGFAHIDGDHLTMLNVYHAFKQNREDSQWCYEHFVN 181
TAMLSVPQC+VRP E RT ADEAK FAHIDGDHLT+LNVYH+FKQN+ED QWCY++F+N
Sbjct: 535 TAMLSVPQCWVRPNEMRTEADEAKARFAHIDGDHLTLLNVYHSFKQNQEDPQWCYDNFIN 594
Query: 182 YRSLKAADNVRIQLSRIMDRFNLRRSSTDFSSKDYYVNIRKALVSGFFMQVAHLERSGHY 361
YR++K AD VR QLSR+MD++NLRR STDF S+DYY+NIRKALV+GFFMQVAHLERSGHY
Sbjct: 595 YRTMKTADTVRTQLSRVMDKYNLRRVSTDFKSRDYYLNIRKALVAGFFMQVAHLERSGHY 654
Query: 362 LTVKDNQIVHLHPSTCLDHKPEWVLYNEFVLTTKNFIRTVCEVKPEWLVKVAPQYYDMSN 541
+TVKDNQ+V+LHPST LDHKPEW LYNEFVLTTKNFIRTV +V+PEWL+++APQYYD+ N
Sbjct: 655 VTVKDNQLVNLHPSTVLDHKPEWALYNEFVLTTKNFIRTVTDVRPEWLLQIAPQYYDLDN 714
Query: 542 FPPCAAKEIIERIINRMQ 595
FP K + ++ +Q
Sbjct: 715 FPDGDTKRKLTTVMQTLQ 732
>sp|O22899|DHX15_ARATH Putative pre-mRNA splicing factor ATP-dependent RNA helicase
Length = 729
Score = 313 bits (802), Expect = 2e-85
Identities = 141/201 (70%), Positives = 171/201 (85%)
Frame = +2
Query: 2 TAMLSVPQCFVRPTEARTAADEAKMGFAHIDGDHLTMLNVYHAFKQNREDSQWCYEHFVN 181
+AMLSVP CFVRP EA+ AADEAK F HIDGDHLT+LNVYHA+KQN ED WC+E+FVN
Sbjct: 522 SAMLSVPNCFVRpreAQKAADEAKARFGHIDGDHLTLLNVYHAYKQNNEDPNWCFENFVN 581
Query: 182 YRSLKAADNVRIQLSRIMDRFNLRRSSTDFSSKDYYVNIRKALVSGFFMQVAHLERSGHY 361
R++K+ADNVR QL RIM RFNL+ STDF+S+DYYVNIRKA+++G+FMQVAHLER+GHY
Sbjct: 582 NRAMKSADNVRQQLVRIMSRFNLKMCSTDFNSRDYYVNIRKAMLAGYFMQVAHLERTGHY 641
Query: 362 LTVKDNQIVHLHPSTCLDHKPEWVLYNEFVLTTKNFIRTVCEVKPEWLVKVAPQYYDMSN 541
LTVKDNQ+VHLHPS CLDHKPEWV+YNE+VLTT+NFIRTV +++ EWLV VA YYD+SN
Sbjct: 642 LTVKDNQVVHLHPSNCLDHKPEWVIYNEYVLTTRNFIRTVTDIRGEWLVDVAQHYYDLSN 701
Query: 542 FPPCAAKEIIERIINRMQNGK 604
FP C AK +E++ + + K
Sbjct: 702 FPNCEAKRALEKLYKKREREK 722
>sp|P53131|PRP43_YEAST Pre-mRNA splicing factor RNA helicase PRP43 (Helicase JA1)
Length = 767
Score = 240 bits (612), Expect = 3e-63
Identities = 121/212 (57%), Positives = 155/212 (73%), Gaps = 12/212 (5%)
Frame = +2
Query: 5 AMLSVPQCFVRPTEARTAADEAKMGFAHIDGDHLTMLNVYHAFKQNREDS----QWCYEH 172
AMLSVP F+RPT+ + AD+AK FAH DGDH+T+LNVYHAFK + +WC +H
Sbjct: 547 AMLSVPNVFIRPTKDKKRADDAKNIFAHPDGDHITLLNVYHAFKSDEAYEYGIHKWCRDH 606
Query: 173 FVNYRSLKAADNVRIQLSRIMDRFNLRRSSTDFSSKDYYVNIRKALVSGFFMQVAHLERS 352
++NYRSL AADN+R QL R+M+R+NL ++TD+ S Y+ NIRKAL SGFFMQVA +RS
Sbjct: 607 YLNYRSLSAADNIRSQLERLMNRYNLELNTTDYESPKYFDNIRKALASGFFMQVAK-KRS 665
Query: 353 GH--YLTVKDNQIVHLHPSTCLDHKPEWVLYNEFVLTTKNFIRTVCEVKPEWLVKVAPQY 526
G Y+TVKDNQ V +HPST L H EWV+YNEFVLT+KN+IRTV V+PEWL+++AP Y
Sbjct: 666 GAKGYITVKDNQDVLIHPSTVLGHDAEWVIYNEFVLTSKNYIRTVTSVRPEWLIEIAPAY 725
Query: 527 YDMSNFPPCAAKEIIERI------INRMQNGK 604
YD+SNF K +ERI +N ++ GK
Sbjct: 726 YDLSNFQKGDVKLSLERIKEKVDRLNELKQGK 757
>sp|O42945|DHX15_SCHPO Probable pre-mRNA splicing factor RNA helicase prp43
Length = 735
Score = 226 bits (577), Expect = 3e-59
Identities = 107/182 (58%), Positives = 136/182 (74%), Gaps = 1/182 (0%)
Frame = +2
Query: 2 TAMLSVPQCFVRPTEARTAADEAKMGFAHIDGDHLTMLNVYHAFKQNREDSQWCYEHFVN 181
TA+LSVP FVRP AR ADE + F H DGDHLT+LNVYHA+K + WC+ HF++
Sbjct: 528 TALLSVPNVFVRPNSARKLADEMRQQFTHPDGDHLTLLNVYHAYKSGEGTADWCWNHFLS 587
Query: 182 YRSLKAADNVRIQLSRIMDRFNLRRSSTDFSSKDYYVNIRKALVSGFFMQVAHLERSG-H 358
+R+L +ADNVR QL R M+R + ST F K+YYVNIR+ALVSGFFMQVA +G +
Sbjct: 588 HRALISADNVRKQLRRTMERQEVELISTPFDDKNYYVNIRRALVSGFFMQVAKKSANGKN 647
Query: 359 YLTVKDNQIVHLHPSTCLDHKPEWVLYNEFVLTTKNFIRTVCEVKPEWLVKVAPQYYDMS 538
Y+T+KDNQ+V LHPS L PEWV+YNEFVLTTK+FIR V ++PEWL+++AP YYD+
Sbjct: 648 YVTMKDNQVVSLHPSCGLSVTPEWVVYNEFVLTTKSFIRNVTAIRPEWLIELAPNYYDLD 707
Query: 539 NF 544
+F
Sbjct: 708 DF 709
>sp|O17438|DHX15_STRPU Putative pre-mRNA splicing factor ATP-dependent RNA helicase PRP1
Length = 455
Score = 162 bits (410), Expect = 7e-40
Identities = 74/97 (76%), Positives = 88/97 (90%)
Frame = +2
Query: 2 TAMLSVPQCFVRPTEARTAADEAKMGFAHIDGDHLTMLNVYHAFKQNREDSQWCYEHFVN 181
TAMLSVPQCF+RP EA+ ADEAKM FAHIDGDHLT+LNVYHAFKQN ED QWCY++F+
Sbjct: 359 TAMLSVPQCFLRPNEAKKLADEAKMRFAHIDGDHLTLLNVYHAFKQNNEDPQWCYDNFIQ 418
Query: 182 YRSLKAADNVRIQLSRIMDRFNLRRSSTDFSSKDYYV 292
YRSLK+AD+VR QL+RIMDRF L+R+ST+F+SKDYY+
Sbjct: 419 YRSLKSADSVRQQLARIMDRFALQRTSTNFNSKDYYL 455
>sp|Q14562|DHX8_HUMAN ATP-dependent helicase DHX8 (RNA helicase HRH1) (DEAH-box protein 8)
Length = 1220
Score = 152 bits (383), Expect = 9e-37
Identities = 76/180 (42%), Positives = 115/180 (63%), Gaps = 1/180 (0%)
Frame = +2
Query: 5 AMLSVPQCFVRPTEARTAADEAKMGFAHIDGDHLTMLNVYHAFKQNREDSQWCYEHFVNY 184
+MLSV F RP + + AD+ K F +GDHLT+L VY+++K N+ + WCYE+F+
Sbjct: 1010 SMLSVQNVFYRPKDKQALADQKKAKFHQTEGDHLTLLAVYNSWKNNKFSNPWCYENFIQA 1069
Query: 185 RSLKAADNVRIQLSRIMDRFNLRRSSTDFSSKDYYVNIRKALVSGFFMQVAHLERSGHYL 364
RSL+ A ++R Q+ IMDR L S S+ V ++KA+ SGFF A + Y
Sbjct: 1070 RSLRRAQDIRKQMLGIMDRHKLDVVSCGKST----VRVQKAICSGFFRNAAKKDPQEGYR 1125
Query: 365 TVKDNQIVHLHPSTCL-DHKPEWVLYNEFVLTTKNFIRTVCEVKPEWLVKVAPQYYDMSN 541
T+ D Q+V++HPS+ L + +PEWV+Y+E VLTTK ++R V + P WLV+ AP ++ +S+
Sbjct: 1126 TLIDQQVVYIHPSSALFNRQPEWVVYHELVLTTKEYMREVTTIDPRWLVEFAPAFFKVSD 1185
>sp|O60231|DHX16_HUMAN Putative pre-mRNA splicing factor RNA helicase (ATP-dependent RNA
helicase #3) (DEAH-box protein 16)
Length = 1041
Score = 150 bits (380), Expect = 2e-36
Identities = 82/194 (42%), Positives = 119/194 (61%), Gaps = 2/194 (1%)
Frame = +2
Query: 5 AMLSVPQC-FVRPTEARTAADEAKMGFAHIDGDHLTMLNVYHAFKQNREDSQWCYEHFVN 181
AMLSV F RP + AD A++ F GDHL +LNVY + ++ SQWCYE+FV
Sbjct: 845 AMLSVNNSIFYRPKDKVVHADNARVNFFLPGGDHLVLLNVYTQWAESGYSSQWCYENFVQ 904
Query: 182 YRSLKAADNVRIQLSRIMDRFNLRRSSTDFSSKDYYVNIRKALVSGFFMQVAHLERSGHY 361
+RS++ A +VR QL +++R + SS Y+ +RKA+ +G+F A L RSG Y
Sbjct: 905 FRSMRRARDVREQLEGLLERVEVGLSSCQGD----YIRVRKAITAGYFYHTARLTRSG-Y 959
Query: 362 LTVKDNQIVHLHPSTCL-DHKPEWVLYNEFVLTTKNFIRTVCEVKPEWLVKVAPQYYDMS 538
TVK Q V +HP++ L + +P W+LY+E VLTTK F+R V E++ WL++VAP YY
Sbjct: 960 RTVKQQQTVFIHPNSSLFEQQPRWLLYHELVLTTKEFMRQVLEIESSWLLEVAPHYYKAK 1019
Query: 539 NFPPCAAKEIIERI 580
AK++ ++I
Sbjct: 1020 ELEDPHAKKMPKKI 1033
>sp|Q7YR39|DHX16_PANTR Putative pre-mRNA splicing factor RNA helicase (ATP-dependent RNA
helicase #3) (DEAH-box protein 16)
Length = 1044
Score = 150 bits (380), Expect = 2e-36
Identities = 82/194 (42%), Positives = 119/194 (61%), Gaps = 2/194 (1%)
Frame = +2
Query: 5 AMLSVPQC-FVRPTEARTAADEAKMGFAHIDGDHLTMLNVYHAFKQNREDSQWCYEHFVN 181
AMLSV F RP + AD A++ F GDHL +LNVY + ++ SQWCYE+FV
Sbjct: 848 AMLSVNNSIFYRPKDKVVHADNARVNFFLPGGDHLVLLNVYTQWAESGYSSQWCYENFVQ 907
Query: 182 YRSLKAADNVRIQLSRIMDRFNLRRSSTDFSSKDYYVNIRKALVSGFFMQVAHLERSGHY 361
+RS++ A +VR QL +++R + SS Y+ +RKA+ +G+F A L RSG Y
Sbjct: 908 FRSMRRARDVREQLEGLLERVEVGLSSCQGD----YIRVRKAITAGYFYHTARLTRSG-Y 962
Query: 362 LTVKDNQIVHLHPSTCL-DHKPEWVLYNEFVLTTKNFIRTVCEVKPEWLVKVAPQYYDMS 538
TVK Q V +HP++ L + +P W+LY+E VLTTK F+R V E++ WL++VAP YY
Sbjct: 963 RTVKQQQTVFIHPNSSLFEQQPRWLLYHELVLTTKEFMRQVLEIESSWLLEVAPHYYKAK 1022
Query: 539 NFPPCAAKEIIERI 580
AK++ ++I
Sbjct: 1023 ELEDPHAKKMPKKI 1036
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 83,199,775
Number of Sequences: 369166
Number of extensions: 1790886
Number of successful extensions: 5075
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4913
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5029
length of database: 68,354,980
effective HSP length: 106
effective length of database: 48,773,070
effective search space used: 5267491560
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)