Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_007_O15
(423 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q13526|PIN1_HUMAN Peptidyl-prolyl cis-trans isomerase NI... 168 5e-42
sp|Q9QUR7|PIN1_MOUSE Peptidyl-prolyl cis-trans isomerase NI... 166 2e-41
sp|P54353|DOD_DROME Dodo protein 141 6e-34
sp|O74448|PIN1_SCHPO Peptidyl-prolyl cis-trans isomerase pin1 135 3e-32
sp|O60045|SSP1_NEUCR Peptidyl-prolyl cis-trans isomerase ss... 133 2e-31
sp|Q9SL42|PIN1_ARATH Peptidyl-prolyl cis-trans isomerase 1 ... 125 4e-29
sp|Q94G00|PIN1_MALDO Peptidyl-prolyl cis-trans isomerase 1 ... 121 7e-28
sp|Q9LEK8|PIN1_DIGLA Peptidyl-prolyl cis-trans isomerase 1 ... 118 6e-27
sp|P22696|ESS1_YEAST Peptidyl-prolyl cis-trans isomerase ES... 108 5e-24
sp|P24327|PRSA_BACSU Foldase protein prsA precursor 68 9e-12
>sp|Q13526|PIN1_HUMAN Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (Rotamase
Pin1) (PPIase Pin1)
Length = 163
Score = 168 bits (425), Expect = 5e-42
Identities = 84/132 (63%), Positives = 99/132 (75%), Gaps = 8/132 (6%)
Frame = +1
Query: 4 SQWEFPAVAAEN--------TSSVKCSHLLVKHKESRRASSWREANITRTKEEALELLKS 159
SQWE P+ + + + V+CSHLLVKH +SRR SSWR+ ITRTKEEALEL+
Sbjct: 32 SQWERPSGNSSSGGKNGQGEPARVRCSHLLVKHSQSRRPSSWRQEKITRTKEEALELING 91
Query: 160 YEEKIRSGECSFASLAEQFSDCSSAKRGGDLGHFKRGQMQKPFEDVGFSLKIGEMSGPVW 339
Y +KI+SGE F SLA QFSDCSSAK GDLG F RGQMQKPFED F+L+ GEMSGPV+
Sbjct: 92 YIQKIKSGEEDFESLASQFSDCSSAKARGDLGAFSRGQMQKPFEDASFALRTGEMSGPVF 151
Query: 340 TDSGVHLIFRTE 375
TDSG+H+I RTE
Sbjct: 152 TDSGIHIILRTE 163
>sp|Q9QUR7|PIN1_MOUSE Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (Rotamase
Pin1) (PPIase Pin1)
Length = 165
Score = 166 bits (420), Expect = 2e-41
Identities = 83/134 (61%), Positives = 98/134 (73%), Gaps = 10/134 (7%)
Frame = +1
Query: 4 SQWEFPAVAAE----------NTSSVKCSHLLVKHKESRRASSWREANITRTKEEALELL 153
SQWE P+ + + V+CSHLLVKH +SRR SSWR+ ITR+KEEALEL+
Sbjct: 32 SQWERPSGGSTVGGSSKNGQGEPAKVRCSHLLVKHSQSRRPSSWRQEKITRSKEEALELI 91
Query: 154 KSYEEKIRSGECSFASLAEQFSDCSSAKRGGDLGHFKRGQMQKPFEDVGFSLKIGEMSGP 333
Y +KI+SGE F SLA QFSDCSSAK GDLG F RGQMQKPFED F+L+ GEMSGP
Sbjct: 92 NGYIQKIKSGEEDFESLASQFSDCSSAKARGDLGPFSRGQMQKPFEDASFALRTGEMSGP 151
Query: 334 VWTDSGVHLIFRTE 375
V+TDSG+H+I RTE
Sbjct: 152 VFTDSGIHIILRTE 165
>sp|P54353|DOD_DROME Dodo protein
Length = 166
Score = 141 bits (355), Expect = 6e-34
Identities = 75/134 (55%), Positives = 86/134 (64%), Gaps = 11/134 (8%)
Frame = +1
Query: 1 ESQWEFPAVAAENTSS-----------VKCSHLLVKHKESRRASSWREANITRTKEEALE 147
ESQW+ P A+ V C HLLVKHK SRR SSWREANITRTKEEA
Sbjct: 31 ESQWDQPTEPAKKAGGGSAGGGDAPDEVHCLHLLVKHKGSRRPSSWREANITRTKEEAQL 90
Query: 148 LLKSYEEKIRSGECSFASLAEQFSDCSSAKRGGDLGHFKRGQMQKPFEDVGFSLKIGEMS 327
LL+ Y KI E +F LA +SDCSSAKRGGDLG F RGQMQ FED F L + ++S
Sbjct: 91 LLEVYRNKIVQQEATFDELARSYSDCSSAKRGGDLGKFGRGQMQAAFEDAAFKLNVNQLS 150
Query: 328 GPVWTDSGVHLIFR 369
G V +DSG+H+I R
Sbjct: 151 GIVDSDSGLHIILR 164
>sp|O74448|PIN1_SCHPO Peptidyl-prolyl cis-trans isomerase pin1
Length = 175
Score = 135 bits (341), Expect = 3e-32
Identities = 68/123 (55%), Positives = 87/123 (70%)
Frame = +1
Query: 1 ESQWEFPAVAAENTSSVKCSHLLVKHKESRRASSWREANITRTKEEALELLKSYEEKIRS 180
E Q A N+ ++ SHLLVKH+ESRR SSW+E +ITR+KEEA +L + YE+ ++S
Sbjct: 51 ELQESVTPTEASNSPKIRASHLLVKHRESRRPSSWKEEHITRSKEEARKLAEHYEQLLKS 110
Query: 181 GECSFASLAEQFSDCSSAKRGGDLGHFKRGQMQKPFEDVGFSLKIGEMSGPVWTDSGVHL 360
G S LA + SDCSSA+RGG+LG F R +MQKPFED F+LK GE+SG V T SG H+
Sbjct: 111 GSVSMHDLAMKESDCSSARRGGELGEFGRDEMQKPFEDAAFALKPGEISGVVETSSGFHI 170
Query: 361 IFR 369
I R
Sbjct: 171 IQR 173
>sp|O60045|SSP1_NEUCR Peptidyl-prolyl cis-trans isomerase ssp-1 (PPIase ssp1)
Length = 186
Score = 133 bits (334), Expect = 2e-31
Identities = 65/107 (60%), Positives = 82/107 (76%)
Frame = +1
Query: 49 VKCSHLLVKHKESRRASSWREANITRTKEEALELLKSYEEKIRSGECSFASLAEQFSDCS 228
++C+HLLVKH +SRR SSWRE+ ITRTK+EAL L+ +E++I+SG S LA SDCS
Sbjct: 72 IRCAHLLVKHNQSRRPSSWRESEITRTKQEALTTLQGFEQRIKSGSISLGELALTESDCS 131
Query: 229 SAKRGGDLGHFKRGQMQKPFEDVGFSLKIGEMSGPVWTDSGVHLIFR 369
SA++ GDLG+F RG MQK FED F+LK GE+SG V T SG+HLI R
Sbjct: 132 SARKRGDLGYFGRGDMQKEFEDAAFALKPGEISGIVDTASGLHLIER 178
>sp|Q9SL42|PIN1_ARATH Peptidyl-prolyl cis-trans isomerase 1 (Rotamase Pin1) (PPIase Pin1)
(PIN1At)
Length = 119
Score = 125 bits (314), Expect = 4e-29
Identities = 63/112 (56%), Positives = 83/112 (74%), Gaps = 4/112 (3%)
Frame = +1
Query: 49 VKCSHLLVKHKESRRASSWREAN----ITRTKEEALELLKSYEEKIRSGECSFASLAEQF 216
VK SH+L+KH+ SRR +SW++ +T T+E A+E LKS E I SG+ +F +A +
Sbjct: 7 VKASHILIKHQGSRRKASWKDPEGKIILTTTREAAVEQLKSIREDIVSGKANFEEVATRV 66
Query: 217 SDCSSAKRGGDLGHFKRGQMQKPFEDVGFSLKIGEMSGPVWTDSGVHLIFRT 372
SDCSSAKRGGDLG F RGQMQKPFE+ ++LK+G++S V TDSGVH+I RT
Sbjct: 67 SDCSSAKRGGDLGSFGRGQMQKPFEEATYALKVGDISDIVDTDSGVHIIKRT 118
>sp|Q94G00|PIN1_MALDO Peptidyl-prolyl cis-trans isomerase 1 (Rotamase Pin1) (PPIase Pin1)
(MdPin1)
Length = 121
Score = 121 bits (303), Expect = 7e-28
Identities = 63/114 (55%), Positives = 82/114 (71%), Gaps = 4/114 (3%)
Frame = +1
Query: 43 SSVKCSHLLVKHKESRRASSWR--EANITR--TKEEALELLKSYEEKIRSGECSFASLAE 210
+ V+ SH+L+KH+ SRR +SW+ E I R T++ A+ LK+ + I SG+ F LA
Sbjct: 7 NQVRASHILIKHQGSRRKASWKDPEGQIIRNTTRDSAVSQLKALRDDILSGKAKFDDLAA 66
Query: 211 QFSDCSSAKRGGDLGHFKRGQMQKPFEDVGFSLKIGEMSGPVWTDSGVHLIFRT 372
++SDCSSAKRGGDLG F R QMQKPFE+ F+LK+GEMS V TDSGVH+I RT
Sbjct: 67 RYSDCSSAKRGGDLGPFGRNQMQKPFEEATFALKVGEMSDIVDTDSGVHIIKRT 120
>sp|Q9LEK8|PIN1_DIGLA Peptidyl-prolyl cis-trans isomerase 1 (Rotamase Pin1) (PPIase Pin1)
(DlPar13)
Length = 118
Score = 118 bits (295), Expect = 6e-27
Identities = 59/116 (50%), Positives = 83/116 (71%), Gaps = 4/116 (3%)
Frame = +1
Query: 37 NTSSVKCSHLLVKHKESRRASSWREAN----ITRTKEEALELLKSYEEKIRSGECSFASL 204
++ V+ SH+L+KH+ SRR SSW++ + T+++A+ L+S +++ S SF+ L
Sbjct: 2 SSEKVRASHILIKHQGSRRKSSWKDPDGSLISATTRDDAVSQLQSLRQELLSDPASFSDL 61
Query: 205 AEQFSDCSSAKRGGDLGHFKRGQMQKPFEDVGFSLKIGEMSGPVWTDSGVHLIFRT 372
A + S CSSAKRGGDLG F RGQMQKPFE+ F+LK+GE+S V TDSGVH+I RT
Sbjct: 62 ASRHSHCSSAKRGGDLGPFGRGQMQKPFEEATFALKVGEISDIVDTDSGVHIIKRT 117
>sp|P22696|ESS1_YEAST Peptidyl-prolyl cis-trans isomerase ESS1 (PPIase ESS1)
(Processing/termination factor 1) (Parvulin ESS1)
Length = 170
Score = 108 bits (270), Expect = 5e-24
Identities = 62/133 (46%), Positives = 84/133 (63%), Gaps = 11/133 (8%)
Frame = +1
Query: 4 SQWEFPAVA---------AENTSSVKCSHLLVKHKESRRASSWREANITRTKEEALELLK 156
SQWE P ++ V+C H+L+KHK+SRR +S R NIT +K++A + LK
Sbjct: 36 SQWEEPEGTNKDQLHKHLRDHPVRVRCLHILIKHKDSRRPASHRSENITISKQDATDELK 95
Query: 157 SYEEKIR--SGECSFASLAEQFSDCSSAKRGGDLGHFKRGQMQKPFEDVGFSLKIGEMSG 330
+ ++ S SF +LA++ SDCSS KRGGDLG F RG+MQ FED F LK+GE+S
Sbjct: 96 TLITRLDDDSKTNSFEALAKERSDCSSYKRGGDLGWFGRGEMQPSFEDAAFQLKVGEVSD 155
Query: 331 PVWTDSGVHLIFR 369
V + SGVH+I R
Sbjct: 156 IVESGSGVHVIKR 168
>sp|P24327|PRSA_BACSU Foldase protein prsA precursor
Length = 292
Score = 67.8 bits (164), Expect = 9e-12
Identities = 44/110 (40%), Positives = 59/110 (53%), Gaps = 1/110 (0%)
Frame = +1
Query: 49 VKCSHLLVKHKESRRASSWREANITRTKEEALELLKSYEEKIRSGECSFASLAEQFSDCS 228
++ SH+LV K +T EE E+K++ GE F LA+++S S
Sbjct: 137 IRASHILVADK--------------KTAEEV-------EKKLKKGE-KFEDLAKEYSTDS 174
Query: 229 SAKRGGDLGHF-KRGQMQKPFEDVGFSLKIGEMSGPVWTDSGVHLIFRTE 375
SA +GGDLG F K GQM + F F LK GE+S PV T G H+I +TE
Sbjct: 175 SASKGGDLGWFAKEGQMDETFSKAAFKLKTGEVSDPVKTQYGYHIIKKTE 224
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 46,316,007
Number of Sequences: 369166
Number of extensions: 821913
Number of successful extensions: 2369
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2326
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2360
length of database: 68,354,980
effective HSP length: 99
effective length of database: 50,066,215
effective search space used: 2052714815
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)