Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_007_O08
(731 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|O43657|TSN6_HUMAN Tetraspanin-6 (Tspan-6) (Transmembrane... 41 0.003
sp|O60637|TSN3_HUMAN Tetraspanin-3 (Tspan-3) (Transmembrane... 41 0.003
sp|Q62283|TSN7_MOUSE Tetraspanin-7 (Tspan-7) (Transmembrane... 40 0.008
sp|Q9UKR8|TNS16_HUMAN Tetraspanin-16 (Tspan-16) (Transmembr... 39 0.011
sp|O60635|TSN1_HUMAN Tetraspanin-1 (Tspan-1) (Tetraspan NET... 39 0.019
sp|Q9QY33|TSN3_MOUSE Tetraspanin-3 (Tspan-3) (Transmembrane... 38 0.024
sp|Q7YQL0|TSN7_PANTR Tetraspanin-7 (Tspan-7) (Transmembrane... 37 0.041
sp|P41732|TSN7_HUMAN Tetraspanin-7 (Tspan-7) (Transmembrane... 37 0.041
sp|Q7YQK9|TSN7_PONPY Tetraspanin-7 (Tspan-7) (Transmembrane... 37 0.041
sp|Q5RC27|TSN1_PONPY Tetraspanin-1 (Tspan-1) 37 0.054
>sp|O43657|TSN6_HUMAN Tetraspanin-6 (Tspan-6) (Transmembrane 4 superfamily member 6)
(T245 protein) (Tetraspanin TM4-D) (A15 homolog)
Length = 245
Score = 41.2 bits (95), Expect = 0.003
Identities = 34/145 (23%), Positives = 53/145 (36%), Gaps = 1/145 (0%)
Frame = +3
Query: 210 SLVQQNATSIGAIAFAVGCVLVALAILGIIAVCCCSXXXXXXXXXXXXXXXXXGLIVLIA 389
SL+ + AT++ + A G V++ L G A C S L+ I
Sbjct: 51 SLLNEKATNVPFVLIATGTVIILLGTFGCFATCRASAWMLKLYAMFLTLVFLVELVAAIV 110
Query: 390 FYGANSQTKIFVPLVNYLQTGIINKYKDIKST-EPESIFVNVIQITANCCGLYNYTDFNS 566
+ + K N + K ST + S V+ IQ T +CCG+ +Y D+
Sbjct: 111 GFVFRHEIK------NSFKNNYEKALKQYNSTGDYRSHAVDKIQNTLHCCGVTDYRDWTD 164
Query: 567 ATSFNRVAFGSDNKQYNLTFPLSCC 641
++ FP SCC
Sbjct: 165 TNYYSEKG-----------FPKSCC 178
>sp|O60637|TSN3_HUMAN Tetraspanin-3 (Tspan-3) (Transmembrane 4 superfamily member 8)
(Tetraspanin TM4-A)
Length = 253
Score = 41.2 bits (95), Expect = 0.003
Identities = 30/134 (22%), Positives = 54/134 (40%), Gaps = 2/134 (1%)
Frame = +3
Query: 246 IAFAVGCVLVALAILGIIAVCCCSXXXXXXXXXXXXXXXXXGLIVLIAFYGANSQTKIFV 425
+ AVG +L + ++G A S ++V++ Y ++ +
Sbjct: 56 VIIAVGALLFIIGLIGCCATIRESRCGLATFVIILLLVFVTEVVVVVLGYVYRAKVE--- 112
Query: 426 PLVNYLQTGIINKYKDIKSTEPE--SIFVNVIQITANCCGLYNYTDFNSATSFNRVAFGS 599
N + I YK T P+ S ++ +Q +CCG++NY+D+ + F
Sbjct: 113 ---NEVDRSIQKVYKTYNGTNPDAASRAIDYVQRQLHCCGIHNYSDWENTDWFKETK--- 166
Query: 600 DNKQYNLTFPLSCC 641
N + PLSCC
Sbjct: 167 -----NQSVPLSCC 175
>sp|Q62283|TSN7_MOUSE Tetraspanin-7 (Tspan-7) (Transmembrane 4 superfamily member 2)
(Cell surface glycoprotein A15) (PE31) (TALLA homolog)
Length = 249
Score = 39.7 bits (91), Expect = 0.008
Identities = 32/150 (21%), Positives = 61/150 (40%)
Frame = +3
Query: 207 ISLVQQNATSIGAIAFAVGCVLVALAILGIIAVCCCSXXXXXXXXXXXXXXXXXGLIVLI 386
ISL+ +N+T+ + G +V + G A C S L+ I
Sbjct: 48 ISLIAENSTNAPYVLIGTGTTIVVFGLFGCFATCRGSPWMLKLYAMFLSLVFLAELVAGI 107
Query: 387 AFYGANSQTKIFVPLVNYLQTGIINKYKDIKSTEPESIFVNVIQITANCCGLYNYTDFNS 566
+ + + K +L+T + ++ + S V+ +Q + +CCG+ NYT+++S
Sbjct: 108 SGFVFRHEIKD-----TFLRT-YTDAMQNYNGNDERSRAVDHVQRSLSCCGVQNYTNWSS 161
Query: 567 ATSFNRVAFGSDNKQYNLTFPLSCCLYDQD 656
+ F + P SCC+ + D
Sbjct: 162 SPYF-----------LDHGIPPSCCMNETD 180
>sp|Q9UKR8|TNS16_HUMAN Tetraspanin-16 (Tspan-16) (Transmembrane 4 superfamily member 16)
(Tetraspanin TM4-B)
Length = 245
Score = 39.3 bits (90), Expect = 0.011
Identities = 37/156 (23%), Positives = 56/156 (35%), Gaps = 5/156 (3%)
Frame = +3
Query: 189 ADASGVISLVQQNATSIGAIAFAVGCVLVALAILGIIAVCCCSXXXXXXXXXXXXXXXXX 368
A + V+ L +G + +GC+ V L G S
Sbjct: 41 ASLTNVLGLSSAYLLHVGNLCLVMGCITVLLGCAGWYGATKESRGTLLFCILSM------ 94
Query: 369 GLIVLIAFYGANSQTKIFVPLVN-----YLQTGIINKYKDIKSTEPESIFVNVIQITANC 533
+IVLI A + +F P+V + + Y+ + S N++ C
Sbjct: 95 -VIVLIMEVTAATVVLLFFPIVGDVALEHTFVTLRKNYRGYNEPDDYSTQWNLVMEKLKC 153
Query: 534 CGLYNYTDFNSATSFNRVAFGSDNKQYNLTFPLSCC 641
CG+ NYTDF S +SF T+P SCC
Sbjct: 154 CGVNNYTDF-SGSSFEMTT--------GHTYPRSCC 180
>sp|O60635|TSN1_HUMAN Tetraspanin-1 (Tspan-1) (Tetraspan NET-1) (Tetraspanin TM4-C)
Length = 241
Score = 38.5 bits (88), Expect = 0.019
Identities = 41/167 (24%), Positives = 57/167 (34%), Gaps = 2/167 (1%)
Frame = +3
Query: 201 GVISLVQQNATSIGAIAFAVGCVLVALAILGIIAVCCCSXXXXXXXXXXXXXXXXXGLIV 380
G +S ++G A G V+ AL LG S L++
Sbjct: 44 GPLSSSAMQFVNVGYFLIAAGVVVFALGFLGCYGAKTESKCALVTFFFIL-------LLI 96
Query: 381 LIAFYGANSQTKIFVPLVNYLQTGIINKY--KDIKSTEPESIFVNVIQITANCCGLYNYT 554
IA A ++ + + T ++ KD S E + N CCG NYT
Sbjct: 97 FIAEVAAAVVALVYTTMAEHFLTLLVVPAIKKDYGSQEDFTQVWNTTMKGLKCCGFTNYT 156
Query: 555 DFNSATSFNRVAFGSDNKQYNLTFPLSCCLYDQDFTINTTNRDSCIK 695
DF + F N FP CC D NT N ++C K
Sbjct: 157 DFEDSPYFKE----------NSAFPPFCC---NDNVTNTAN-ETCTK 189
>sp|Q9QY33|TSN3_MOUSE Tetraspanin-3 (Tspan-3) (Transmembrane 4 superfamily member 8)
(Tetraspanin TM4-A) (OSP-associated protein 1) (OAP-1)
Length = 253
Score = 38.1 bits (87), Expect = 0.024
Identities = 29/134 (21%), Positives = 53/134 (39%), Gaps = 2/134 (1%)
Frame = +3
Query: 246 IAFAVGCVLVALAILGIIAVCCCSXXXXXXXXXXXXXXXXXGLIVLIAFYGANSQTKIFV 425
+ AVG +L + ++G A S ++V++ Y ++ +
Sbjct: 56 VIIAVGALLFIIGLIGCCATIRESRCGLATFVFILLLVFVTEVVVVVLGYVYRAKVE--- 112
Query: 426 PLVNYLQTGIINKYKDIKSTEPE--SIFVNVIQITANCCGLYNYTDFNSATSFNRVAFGS 599
N + I YK T + S ++ +Q +CCG++NY+D+ + F
Sbjct: 113 ---NEVDRSIQKVYKTYNGTNSDAASRAIDYVQRQLHCCGIHNYSDWENTDWFKETK--- 166
Query: 600 DNKQYNLTFPLSCC 641
N + PLSCC
Sbjct: 167 -----NQSVPLSCC 175
>sp|Q7YQL0|TSN7_PANTR Tetraspanin-7 (Tspan-7) (Transmembrane 4 superfamily member 2)
Length = 244
Score = 37.4 bits (85), Expect = 0.041
Identities = 34/154 (22%), Positives = 60/154 (38%), Gaps = 4/154 (2%)
Frame = +3
Query: 207 ISLVQQNATSIGAIAFAVGCVLVALAILGIIAVCCCSXXXXXXXXXXXXXXXXXGLIVLI 386
ISL+ +N+T+ + G +V + G A C S L+ I
Sbjct: 43 ISLIAENSTNAPYVLIGTGTTIVVFGLFGCFATCRGSPWMLKLYAMFLSLVFLAELVAGI 102
Query: 387 AFYGANSQTKIFVPLVNYLQTGIINKYKDIKST----EPESIFVNVIQITANCCGLYNYT 554
+ + + K +L+T Y D T + S V+ +Q + +CCG+ NYT
Sbjct: 103 SGFVFRHEIKD-----TFLRT-----YTDAMQTYNGNDERSRAVDHVQRSLSCCGVQNYT 152
Query: 555 DFNSATSFNRVAFGSDNKQYNLTFPLSCCLYDQD 656
+++++ F P SCC+ + D
Sbjct: 153 NWSTSPYF-----------LEHGIPPSCCMNETD 175
>sp|P41732|TSN7_HUMAN Tetraspanin-7 (Tspan-7) (Transmembrane 4 superfamily member 2)
(Cell surface glycoprotein A15) (T-cell acute
lymphoblastic leukemia associated antigen 1) (TALLA-1)
(Membrane component, X chromosome, surface marker 1)
(CD231 antigen)
Length = 249
Score = 37.4 bits (85), Expect = 0.041
Identities = 34/154 (22%), Positives = 60/154 (38%), Gaps = 4/154 (2%)
Frame = +3
Query: 207 ISLVQQNATSIGAIAFAVGCVLVALAILGIIAVCCCSXXXXXXXXXXXXXXXXXGLIVLI 386
ISL+ +N+T+ + G +V + G A C S L+ I
Sbjct: 48 ISLIAENSTNAPYVLIGTGTTIVVFGLFGCFATCRGSPWMLKLYAMFLSLVFLAELVAGI 107
Query: 387 AFYGANSQTKIFVPLVNYLQTGIINKYKDIKST----EPESIFVNVIQITANCCGLYNYT 554
+ + + K +L+T Y D T + S V+ +Q + +CCG+ NYT
Sbjct: 108 SGFVFRHEIKD-----TFLRT-----YTDAMQTYNGNDERSRAVDHVQRSLSCCGVQNYT 157
Query: 555 DFNSATSFNRVAFGSDNKQYNLTFPLSCCLYDQD 656
+++++ F P SCC+ + D
Sbjct: 158 NWSTSPYF-----------LEHGIPPSCCMNETD 180
>sp|Q7YQK9|TSN7_PONPY Tetraspanin-7 (Tspan-7) (Transmembrane 4 superfamily member 2)
Length = 244
Score = 37.4 bits (85), Expect = 0.041
Identities = 34/154 (22%), Positives = 60/154 (38%), Gaps = 4/154 (2%)
Frame = +3
Query: 207 ISLVQQNATSIGAIAFAVGCVLVALAILGIIAVCCCSXXXXXXXXXXXXXXXXXGLIVLI 386
ISL+ +N+T+ + G +V + G A C S L+ I
Sbjct: 43 ISLIAENSTNAPYVLIGTGTTIVVFGLFGCFATCRGSPWMLKLYAMFLSLVFLAELVAGI 102
Query: 387 AFYGANSQTKIFVPLVNYLQTGIINKYKDIKST----EPESIFVNVIQITANCCGLYNYT 554
+ + + K +L+T Y D T + S V+ +Q + +CCG+ NYT
Sbjct: 103 SGFVFRHEIKD-----TFLRT-----YTDAMQTYDGKDDRSQAVDHVQRSLSCCGVQNYT 152
Query: 555 DFNSATSFNRVAFGSDNKQYNLTFPLSCCLYDQD 656
+++++ F P SCC+ + D
Sbjct: 153 NWSTSPYF-----------LEHGIPPSCCMNETD 175
>sp|Q5RC27|TSN1_PONPY Tetraspanin-1 (Tspan-1)
Length = 241
Score = 37.0 bits (84), Expect = 0.054
Identities = 42/167 (25%), Positives = 57/167 (34%), Gaps = 2/167 (1%)
Frame = +3
Query: 201 GVISLVQQNATSIGAIAFAVGCVLVALAILGIIAVCCCSXXXXXXXXXXXXXXXXXGLIV 380
G +S ++G A G V+ AL LG S L++
Sbjct: 44 GPLSSSAMQFVNVGYFLIAAGVVVFALGFLGCYGAKTESKCALMTFFFIL-------LLI 96
Query: 381 LIAFYGANSQTKIFVPLVNYLQTGIINKY--KDIKSTEPESIFVNVIQITANCCGLYNYT 554
IA A ++ + + T ++ KD S E + N CCG NYT
Sbjct: 97 FIAEVAAAVVALVYTTMAEHFLTLLVVPAIKKDYGSQEDFTQVWNTTMKGLKCCGFTNYT 156
Query: 555 DFNSATSFNRVAFGSDNKQYNLTFPLSCCLYDQDFTINTTNRDSCIK 695
DF S + N FP CC D NT N D+C K
Sbjct: 157 DFED----------SPYLKENHAFPPFCC---NDNITNTAN-DTCTK 189
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 82,920,399
Number of Sequences: 369166
Number of extensions: 1665679
Number of successful extensions: 5250
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5012
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5229
length of database: 68,354,980
effective HSP length: 108
effective length of database: 48,403,600
effective search space used: 6534486000
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)