Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_007_N18
(923 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P24346|AN3_XENLA Putative ATP-dependent RNA helicase An3 192 9e-49
sp|O00571|DDX3X_HUMAN DEAD-box protein 3, X-chromosomal (He... 191 2e-48
sp|P16381|PL10_MOUSE Putative ATP-dependent RNA helicase PL10 190 6e-48
sp|Q62167|DDX3X_MOUSE DEAD-box protein 3, X-chromosomal (DE... 189 7e-48
sp|Q5RF43|DDX3Y_PONPY DEAD-box protein 3, Y-chromosomal 187 5e-47
sp|O15523|DDX3Y_HUMAN DEAD-box protein 3, Y-chromosomal 186 6e-47
sp|Q62095|DDX3Y_MOUSE DEAD-box protein 3, Y-chromosomal (DE... 184 3e-46
sp|Q6GVM6|DDX3Y_PANTR DEAD-box protein 3, Y-chromosomal 184 4e-46
sp|O13370|DED1_SCHPO ATP-dependent RNA helicase ded1 165 1e-40
sp|P06634|DED1_YEAST Probable ATP-dependent RNA helicase DED1 161 2e-39
>sp|P24346|AN3_XENLA Putative ATP-dependent RNA helicase An3
Length = 697
Score = 192 bits (489), Expect = 9e-49
Identities = 106/200 (53%), Positives = 125/200 (62%), Gaps = 3/200 (1%)
Frame = +3
Query: 3 YVDENEKRXXXXXXXXXXXXXXXXXVFVETKRGADALEGFLHTEGFRVASIHGDRSQTDR 182
+V+E +KR VFVETK+GADALE FL+ EG+ SIHGDRSQ DR
Sbjct: 462 WVEEMDKRSFLLDLLNATGKDSLTLVFVETKKGADALEDFLYHEGYACTSIHGDRSQRDR 521
Query: 183 ELALQCFREGSTPILVATAVAARGLDIPNVKFVINYDLPTDIEEYVHRIGRTGRVGNLGE 362
E AL FR G +PILVATAVAARGLDI NVK VIN+DLP+DIEEYVHRIGRTGRVGNLG
Sbjct: 522 EEALHQFRSGKSPILVATAVAARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRVGNLGL 581
Query: 363 AISFYTDKNNNVAKELVDILLEANQIVPDWLREKIGEAHR---XXXXXXXXXXXXXXXXR 533
A SF+ +KN N+ K+L+D+L+EA Q VP WL E H
Sbjct: 582 ATSFFNEKNINITKDLLDLLVEAKQEVPSWLENMAYEQHHKSSSRGRSKSRFSGGFGAKD 641
Query: 534 YMSSASGAPSYGTSRDYRQS 593
Y S+ S+G+SR R S
Sbjct: 642 YRQSSGAGSSFGSSRGGRSS 661
>sp|O00571|DDX3X_HUMAN DEAD-box protein 3, X-chromosomal (Helicase-like protein 2) (HLP2)
(DEAD-box, X isoform)
Length = 662
Score = 191 bits (485), Expect = 2e-48
Identities = 112/222 (50%), Positives = 133/222 (59%)
Frame = +3
Query: 3 YVDENEKRXXXXXXXXXXXXXXXXXVFVETKRGADALEGFLHTEGFRVASIHGDRSQTDR 182
+V+E++KR VFVETK+GAD+LE FL+ EG+ SIHGDRSQ DR
Sbjct: 421 WVEESDKRSFLLDLLNATGKDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDR 480
Query: 183 ELALQCFREGSTPILVATAVAARGLDIPNVKFVINYDLPTDIEEYVHRIGRTGRVGNLGE 362
E AL FR G +PILVATAVAARGLDI NVK VIN+DLP+DIEEYVHRIGRTGRVGNLG
Sbjct: 481 EEALHQFRSGKSPILVATAVAARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRVGNLGL 540
Query: 363 AISFYTDKNNNVAKELVDILLEANQIVPDWLREKIGEAHRXXXXXXXXXXXXXXXXRYMS 542
A SF+ ++N N+ K+L+D+L+EA Q VP WL E H R S
Sbjct: 541 ATSFFNERNINITKDLLDLLVEAKQEVPSWLENMAYEHH------------YKGSSRGRS 588
Query: 543 SASGAPSYGTSRDYRQSQSHVDTRTQRQISYDESSFSSMRNS 668
+S +RDYRQS SSFSS R S
Sbjct: 589 KSSRFSGGFGARDYRQSS-----------GASSSSFSSSRAS 619
>sp|P16381|PL10_MOUSE Putative ATP-dependent RNA helicase PL10
Length = 660
Score = 190 bits (482), Expect = 6e-48
Identities = 112/224 (50%), Positives = 135/224 (60%)
Frame = +3
Query: 3 YVDENEKRXXXXXXXXXXXXXXXXXVFVETKRGADALEGFLHTEGFRVASIHGDRSQTDR 182
+V+E +KR VFVETK+GAD+LE FL+ EG+ SIHGDRSQ DR
Sbjct: 420 WVEEADKRSFLLDLLNATGKDSLILVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDR 479
Query: 183 ELALQCFREGSTPILVATAVAARGLDIPNVKFVINYDLPTDIEEYVHRIGRTGRVGNLGE 362
E AL FR G +PILVATAVAARGLDI NVK VIN+DLP+DIEEYVHRIGRTGRVGNLG
Sbjct: 480 EEALHQFRSGKSPILVATAVAARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRVGNLGL 539
Query: 363 AISFYTDKNNNVAKELVDILLEANQIVPDWLREKIGEAHRXXXXXXXXXXXXXXXXRYMS 542
A SF+ ++N N+ K+L+D+L+EA Q VP WL E H R S
Sbjct: 540 ATSFFNERNINITKDLLDLLVEAKQEVPSWLENMAFEHH------------YKGGSRGRS 587
Query: 543 SASGAPSYGTSRDYRQSQSHVDTRTQRQISYDESSFSSMRNSRN 674
+ + +G +RDYRQS SSFSS R S +
Sbjct: 588 KSRFSGGFG-ARDYRQSS-----------GASSSSFSSGRASNS 619
>sp|Q62167|DDX3X_MOUSE DEAD-box protein 3, X-chromosomal (DEAD-box RNA helicase DEAD3)
(mDEAD3) (Embryonic RNA helicase) (D1Pas1-related
sequence 2)
Length = 662
Score = 189 bits (481), Expect = 7e-48
Identities = 112/222 (50%), Positives = 132/222 (59%)
Frame = +3
Query: 3 YVDENEKRXXXXXXXXXXXXXXXXXVFVETKRGADALEGFLHTEGFRVASIHGDRSQTDR 182
+V+E +KR VFVETK+GAD+LE FL+ EG+ SIHGDRSQ DR
Sbjct: 421 WVEEIDKRSFLLDLLNATGKDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDR 480
Query: 183 ELALQCFREGSTPILVATAVAARGLDIPNVKFVINYDLPTDIEEYVHRIGRTGRVGNLGE 362
E AL FR G +PILVATAVAARGLDI NVK VIN+DLP+DIEEYVHRIGRTGRVGNLG
Sbjct: 481 EEALHQFRSGKSPILVATAVAARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRVGNLGL 540
Query: 363 AISFYTDKNNNVAKELVDILLEANQIVPDWLREKIGEAHRXXXXXXXXXXXXXXXXRYMS 542
A SF+ ++N N+ K+L+D+L+EA Q VP WL E H R S
Sbjct: 541 ATSFFNERNINITKDLLDLLVEAKQEVPSWLENMAFEHH------------YKGSSRGRS 588
Query: 543 SASGAPSYGTSRDYRQSQSHVDTRTQRQISYDESSFSSMRNS 668
+S +RDYRQS SSFSS R S
Sbjct: 589 KSSRFSGGFGARDYRQSS-----------GASSSSFSSSRAS 619
>sp|Q5RF43|DDX3Y_PONPY DEAD-box protein 3, Y-chromosomal
Length = 658
Score = 187 bits (474), Expect = 5e-47
Identities = 105/212 (49%), Positives = 125/212 (58%), Gaps = 18/212 (8%)
Frame = +3
Query: 3 YVDENEKRXXXXXXXXXXXXXXXXXVFVETKRGADALEGFLHTEGFRVASIHGDRSQTDR 182
+V++ +KR VFVETK+GAD+LE FL+ EG+ SIHGDRSQ DR
Sbjct: 419 WVEDLDKRSFLLDLLGATGRDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDR 478
Query: 183 ELALQCFREGSTPILVATAVAARGLDIPNVKFVINYDLPTDIEEYVHRIGRTGRVGNLGE 362
E AL FR G +PILVATAVAARGLDI NV+ VIN+DLP+DIEEYVHRIGRTGRVGNLG
Sbjct: 479 EEALHQFRSGKSPILVATAVAARGLDISNVRHVINFDLPSDIEEYVHRIGRTGRVGNLGL 538
Query: 363 AISFYTDKNNNVAKELVDILLEANQIVPDWLREKIGEAH------------------RXX 488
A SF+ +KN N+ K+L+D+L+EA Q VP WL E H R
Sbjct: 539 ATSFFNEKNMNITKDLLDLLVEAKQEVPSWLENMAYEHHYKGGSRGRSKRFSGGFGARDY 598
Query: 489 XXXXXXXXXXXXXXRYMSSASGAPSYGTSRDY 584
R SS SG YG SR +
Sbjct: 599 RQSSGSSSSGFGASRGSSSRSGGSGYGNSRGF 630
>sp|O15523|DDX3Y_HUMAN DEAD-box protein 3, Y-chromosomal
Length = 660
Score = 186 bits (473), Expect = 6e-47
Identities = 95/159 (59%), Positives = 114/159 (71%)
Frame = +3
Query: 3 YVDENEKRXXXXXXXXXXXXXXXXXVFVETKRGADALEGFLHTEGFRVASIHGDRSQTDR 182
+V++ +KR VFVETK+GAD+LE FL+ EG+ SIHGDRSQ DR
Sbjct: 419 WVEDLDKRSFLLDILGATGSDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDR 478
Query: 183 ELALQCFREGSTPILVATAVAARGLDIPNVKFVINYDLPTDIEEYVHRIGRTGRVGNLGE 362
E AL FR G +PILVATAVAARGLDI NV+ VIN+DLP+DIEEYVHRIGRTGRVGNLG
Sbjct: 479 EEALHQFRSGKSPILVATAVAARGLDISNVRHVINFDLPSDIEEYVHRIGRTGRVGNLGL 538
Query: 363 AISFYTDKNNNVAKELVDILLEANQIVPDWLREKIGEAH 479
A SF+ +KN N+ K+L+D+L+EA Q VP WL E H
Sbjct: 539 ATSFFNEKNMNITKDLLDLLVEAKQEVPSWLENMAYEHH 577
>sp|Q62095|DDX3Y_MOUSE DEAD-box protein 3, Y-chromosomal (DEAD-box RNA helicase DEAD2)
(mDEAD2) (D1Pas1-related sequence 1)
Length = 658
Score = 184 bits (467), Expect = 3e-46
Identities = 107/221 (48%), Positives = 129/221 (58%)
Frame = +3
Query: 3 YVDENEKRXXXXXXXXXXXXXXXXXVFVETKRGADALEGFLHTEGFRVASIHGDRSQTDR 182
+V+E +KR VFVETK+GAD+LE FL E + SIHGDRSQ DR
Sbjct: 420 WVEELDKRSFLLDLLNATGKDSLTLVFVETKKGADSLENFLFQERYACTSIHGDRSQKDR 479
Query: 183 ELALQCFREGSTPILVATAVAARGLDIPNVKFVINYDLPTDIEEYVHRIGRTGRVGNLGE 362
E AL FR G PILVATAVAARGLDI NVK VIN+DLP+DIEEYVHRIGRTGRVGNLG
Sbjct: 480 EEALHQFRSGRKPILVATAVAARGLDISNVKHVINFDLPSDIEEYVHRIGRTGRVGNLGL 539
Query: 363 AISFYTDKNNNVAKELVDILLEANQIVPDWLREKIGEAHRXXXXXXXXXXXXXXXXRYMS 542
A SF+ ++N N+ K+L+D+L+EA Q VP WL E H R S
Sbjct: 540 ATSFFNERNLNITKDLLDLLVEAKQEVPSWLESMAYEHH------------YKGSSRGRS 587
Query: 543 SASGAPSYGTSRDYRQSQSHVDTRTQRQISYDESSFSSMRN 665
+ + +G +RDYRQS + + S S N
Sbjct: 588 KSRFSGGFG-ARDYRQSSGSANAGFNSNRANSSRSSGSSHN 627
>sp|Q6GVM6|DDX3Y_PANTR DEAD-box protein 3, Y-chromosomal
Length = 660
Score = 184 bits (466), Expect = 4e-46
Identities = 93/151 (61%), Positives = 112/151 (74%)
Frame = +3
Query: 3 YVDENEKRXXXXXXXXXXXXXXXXXVFVETKRGADALEGFLHTEGFRVASIHGDRSQTDR 182
+V++ +KR VFVETK+GAD+LE FL+ EG+ SIHGDRSQ DR
Sbjct: 419 WVEDLDKRSFLLDILGAAGTDSLTLVFVETKKGADSLEDFLYHEGYACTSIHGDRSQRDR 478
Query: 183 ELALQCFREGSTPILVATAVAARGLDIPNVKFVINYDLPTDIEEYVHRIGRTGRVGNLGE 362
E AL FR G +PILVATAVAARGLDI NV+ VIN+DLP+DIEEYVHRIGRTGRVGNLG
Sbjct: 479 EEALHQFRSGKSPILVATAVAARGLDISNVRHVINFDLPSDIEEYVHRIGRTGRVGNLGL 538
Query: 363 AISFYTDKNNNVAKELVDILLEANQIVPDWL 455
A SF+ +KN N+ K+L+D+L+EA Q VP WL
Sbjct: 539 ATSFFNEKNINITKDLLDLLVEAKQEVPSWL 569
>sp|O13370|DED1_SCHPO ATP-dependent RNA helicase ded1
Length = 636
Score = 165 bits (418), Expect = 1e-40
Identities = 82/151 (54%), Positives = 104/151 (68%)
Frame = +3
Query: 3 YVDENEKRXXXXXXXXXXXXXXXXXVFVETKRGADALEGFLHTEGFRVASIHGDRSQTDR 182
+V+++EKR +FVETKR AD L +L F SIHGDR+Q +R
Sbjct: 410 HVEDSEKRSYLLDILHTLPPEGLTLIFVETKRMADTLTDYLLNSNFPATSIHGDRTQRER 469
Query: 183 ELALQCFREGSTPILVATAVAARGLDIPNVKFVINYDLPTDIEEYVHRIGRTGRVGNLGE 362
E AL+ FR G T I+VATAVA+RGLDIPNV VINYDLPTDI++YVHRIGRTGR GN G+
Sbjct: 470 ERALELFRSGRTSIMVATAVASRGLDIPNVTHVINYDLPTDIDDYVHRIGRTGRAGNTGQ 529
Query: 363 AISFYTDKNNNVAKELVDILLEANQIVPDWL 455
A++F+ N +AKEL+++L EANQ P +L
Sbjct: 530 AVAFFNRNNKGIAKELIELLQEANQECPSFL 560
>sp|P06634|DED1_YEAST Probable ATP-dependent RNA helicase DED1
Length = 604
Score = 161 bits (408), Expect = 2e-39
Identities = 79/133 (59%), Positives = 101/133 (75%)
Frame = +3
Query: 78 VFVETKRGADALEGFLHTEGFRVASIHGDRSQTDRELALQCFREGSTPILVATAVAARGL 257
+FVETKR AD L FL + FR +IHGDR+Q++RE AL FR G+ +LVATAVAARGL
Sbjct: 404 IFVETKRMADQLTDFLIMQNFRATAIHGDRTQSERERALAAFRSGAATLLVATAVAARGL 463
Query: 258 DIPNVKFVINYDLPTDIEEYVHRIGRTGRVGNLGEAISFYTDKNNNVAKELVDILLEANQ 437
DIPNV VINYDLP+D+++YVHRIGRTGR GN G A +F+ +N+N+ K L +IL EANQ
Sbjct: 464 DIPNVTHVINYDLPSDVDDYVHRIGRTGRAGNTGLATAFFNSENSNIVKGLHEILTEANQ 523
Query: 438 IVPDWLREKIGEA 476
VP +L++ + A
Sbjct: 524 EVPSFLKDAMMSA 536
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 97,427,081
Number of Sequences: 369166
Number of extensions: 1922586
Number of successful extensions: 6645
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 6253
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 6622
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 9462723610
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)