Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_007_N06
(815 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P40926|MDHM_HUMAN Malate dehydrogenase, mitochondrial pr... 329 5e-90
sp|P04636|MDHM_RAT Malate dehydrogenase, mitochondrial prec... 328 1e-89
sp|P00346|MDHM_PIG Malate dehydrogenase, mitochondrial prec... 328 1e-89
sp|P08249|MDHM_MOUSE Malate dehydrogenase, mitochondrial pr... 327 2e-89
sp|O02640|MDHM_CAEEL Probable malate dehydrogenase, mitocho... 307 2e-83
sp|O82399|MDHI_ARATH Probable malate dehydrogenase, glyoxys... 287 2e-77
sp|Q42972|MDHG_ORYSA Malate dehydrogenase, glyoxysomal prec... 285 1e-76
sp|P19446|MDHG_CITLA Malate dehydrogenase, glyoxysomal prec... 281 1e-75
sp|P46488|MDHG_CUCSA Malate dehydrogenase, glyoxysomal prec... 280 3e-75
sp|Q9ZP05|MDHG_ARATH Malate dehydrogenase, glyoxysomal prec... 280 4e-75
>sp|P40926|MDHM_HUMAN Malate dehydrogenase, mitochondrial precursor
Length = 338
Score = 329 bits (844), Expect = 5e-90
Identities = 167/268 (62%), Positives = 198/268 (73%)
Frame = +1
Query: 1 QPMSLLLKKSSAVDRLALYDIAHVKGVAADLSHIETPAVVNGYLGPSELLECLKNSDVVV 180
QP+SLLLK S V RL LYDIAH GVAADLSHIET A V GYLGP +L +CLK DVVV
Sbjct: 38 QPLSLLLKNSPLVSRLTLYDIAHTPGVAADLSHIETKAAVKGYLGPEQLPDCLKGCDVVV 97
Query: 181 IPAGVPRKPGMTRDDLFNTNASIVADLVHGCAQACPKAIICIITNPVNSTVPIAAEILKK 360
IPAGVPRKPGMTRDDLFNTNA+IVA L CAQ CP+A+IC+I NPVNST+PI AE+ KK
Sbjct: 98 IPAGVPRKPGMTRDDLFNTNATIVATLTAACAQHCPEAMICVIANPVNSTIPITAEVFKK 157
Query: 361 AGCYDPKRLFGVTTLDIVRSNTFISEAKHLDVTKMPVPVIGGHSGVTIVPVISQAIPSVS 540
G Y+P ++FGVTTLDIVR+NTF++E K LD ++ VPVIGGH+G TI+P+ISQ P V
Sbjct: 158 HGVYNPNKIFGVTTLDIVRANTFVAELKGLDPARVNVPVIGGHAGKTIIPLISQCTPKVD 217
Query: 541 FPESEISKLTIRIQNAGTEVVEAKAGAGSATLSMAYAGVRFVKRILAAMKGNKNICRVCI 720
FP+ +++ LT RIQ AGTEVV+AKAGAGSATLSMAYAG RFV ++ AM G + +
Sbjct: 218 FPQDQLTALTGRIQEAGTEVVKAKAGAGSATLSMAYAGARFVFSLVDAMNGKEGVVECSF 277
Query: 721 CGIKYNRSKILC*PSFAWT**IEKNLGL 804
+ P IEKNLG+
Sbjct: 278 VKSQETECTYFSTPLLLGKKGIEKNLGI 305
>sp|P04636|MDHM_RAT Malate dehydrogenase, mitochondrial precursor
Length = 338
Score = 328 bits (841), Expect = 1e-89
Identities = 167/268 (62%), Positives = 199/268 (74%)
Frame = +1
Query: 1 QPMSLLLKKSSAVDRLALYDIAHVKGVAADLSHIETPAVVNGYLGPSELLECLKNSDVVV 180
QP+SLLLK S V RL LYDIAH GVAADLSHIET A V GYLGP +L +CLK DVVV
Sbjct: 38 QPLSLLLKNSPLVSRLTLYDIAHTPGVAADLSHIETRANVKGYLGPEQLPDCLKGCDVVV 97
Query: 181 IPAGVPRKPGMTRDDLFNTNASIVADLVHGCAQACPKAIICIITNPVNSTVPIAAEILKK 360
IPAGVPRKPGMTRDDLFNTNA+IVA L CAQ CP+A+ICII+NPVNST+PI AE+ KK
Sbjct: 98 IPAGVPRKPGMTRDDLFNTNATIVATLTAACAQHCPEAMICIISNPVNSTIPITAEVFKK 157
Query: 361 AGCYDPKRLFGVTTLDIVRSNTFISEAKHLDVTKMPVPVIGGHSGVTIVPVISQAIPSVS 540
G Y+P ++FGVTTLDIVR+NTF++E K LD ++ VPVIGGH+G TI+P+ISQ P V
Sbjct: 158 HGVYNPNKIFGVTTLDIVRANTFVAELKGLDPARVNVPVIGGHAGKTIIPLISQCTPKVD 217
Query: 541 FPESEISKLTIRIQNAGTEVVEAKAGAGSATLSMAYAGVRFVKRILAAMKGNKNICRVCI 720
FP+ +++ LT +IQ AGTEVV+AKAGAGSATLSMAYAG RFV ++ AM G + +
Sbjct: 218 FPQDQLATLTGKIQEAGTEVVKAKAGAGSATLSMAYAGARFVFSLVDAMNGKEGVIECSF 277
Query: 721 CGIKYNRSKILC*PSFAWT**IEKNLGL 804
K P +EKNLG+
Sbjct: 278 VQSKETECTYFSTPLLLGKKGLEKNLGI 305
>sp|P00346|MDHM_PIG Malate dehydrogenase, mitochondrial precursor
Length = 338
Score = 328 bits (840), Expect = 1e-89
Identities = 168/268 (62%), Positives = 197/268 (73%)
Frame = +1
Query: 1 QPMSLLLKKSSAVDRLALYDIAHVKGVAADLSHIETPAVVNGYLGPSELLECLKNSDVVV 180
QP+SLLLK S V RL LYDIAH GVAADLSHIET A V GYLGP +L +CLK DVVV
Sbjct: 38 QPLSLLLKNSPLVSRLTLYDIAHTPGVAADLSHIETRATVKGYLGPEQLPDCLKGCDVVV 97
Query: 181 IPAGVPRKPGMTRDDLFNTNASIVADLVHGCAQACPKAIICIITNPVNSTVPIAAEILKK 360
IPAGVPRKPGMTRDDLFNTNA+IVA L CAQ CP A+ICII+NPVNST+PI AE+ KK
Sbjct: 98 IPAGVPRKPGMTRDDLFNTNATIVATLTAACAQHCPDAMICIISNPVNSTIPITAEVFKK 157
Query: 361 AGCYDPKRLFGVTTLDIVRSNTFISEAKHLDVTKMPVPVIGGHSGVTIVPVISQAIPSVS 540
G Y+P ++FGVTTLDIVR+N F++E K LD ++ VPVIGGH+G TI+P+ISQ P V
Sbjct: 158 HGVYNPNKIFGVTTLDIVRANAFVAELKGLDPARVSVPVIGGHAGKTIIPLISQCTPKVD 217
Query: 541 FPESEISKLTIRIQNAGTEVVEAKAGAGSATLSMAYAGVRFVKRILAAMKGNKNICRVCI 720
FP+ ++S LT RIQ AGTEVV+AKAGAGSATLSMAYAG RFV ++ AM G + +
Sbjct: 218 FPQDQLSTLTGRIQEAGTEVVKAKAGAGSATLSMAYAGARFVFSLVDAMNGKEGVVECSF 277
Query: 721 CGIKYNRSKILC*PSFAWT**IEKNLGL 804
+ P IEKNLG+
Sbjct: 278 VKSQETDCPYFSTPLLLGKKGIEKNLGI 305
>sp|P08249|MDHM_MOUSE Malate dehydrogenase, mitochondrial precursor
Length = 338
Score = 327 bits (839), Expect = 2e-89
Identities = 167/268 (62%), Positives = 198/268 (73%)
Frame = +1
Query: 1 QPMSLLLKKSSAVDRLALYDIAHVKGVAADLSHIETPAVVNGYLGPSELLECLKNSDVVV 180
QP+SLLLK S V RL LYDIAH GVAADLSHIET A V GYLGP +L +CLK DVVV
Sbjct: 38 QPLSLLLKNSPLVSRLTLYDIAHTPGVAADLSHIETRANVKGYLGPEQLPDCLKGCDVVV 97
Query: 181 IPAGVPRKPGMTRDDLFNTNASIVADLVHGCAQACPKAIICIITNPVNSTVPIAAEILKK 360
IPAGVPRKPGMTRDDLFNTNA+IVA L CAQ CP+A++CII NPVNST+PI AE+ KK
Sbjct: 98 IPAGVPRKPGMTRDDLFNTNATIVATLTAACAQHCPEAMVCIIANPVNSTIPITAEVFKK 157
Query: 361 AGCYDPKRLFGVTTLDIVRSNTFISEAKHLDVTKMPVPVIGGHSGVTIVPVISQAIPSVS 540
G Y+P ++FGVTTLDIVR+NTF++E K LD ++ VPVIGGH+G TI+P+ISQ P V
Sbjct: 158 HGVYNPNKIFGVTTLDIVRANTFVAELKGLDPARVNVPVIGGHAGKTIIPLISQCTPKVD 217
Query: 541 FPESEISKLTIRIQNAGTEVVEAKAGAGSATLSMAYAGVRFVKRILAAMKGNKNICRVCI 720
FP+ +++ LT RIQ AGTEVV+AKAGAGSATLSMAYAG RFV ++ AM G + +
Sbjct: 218 FPQDQLATLTGRIQEAGTEVVKAKAGAGSATLSMAYAGARFVFSLVDAMNGLEGVVECSF 277
Query: 721 CGIKYNRSKILC*PSFAWT**IEKNLGL 804
K P +EKNLG+
Sbjct: 278 VQSKETECTYFSTPLLLGKKGLEKNLGI 305
>sp|O02640|MDHM_CAEEL Probable malate dehydrogenase, mitochondrial precursor
Length = 341
Score = 307 bits (787), Expect = 2e-83
Identities = 154/235 (65%), Positives = 184/235 (78%)
Frame = +1
Query: 1 QPMSLLLKKSSAVDRLALYDIAHVKGVAADLSHIETPAVVNGYLGPSELLECLKNSDVVV 180
QP+ LLLK+ V LALYD+ + GVAADLSHI++ A V + GP EL ++N+DV+V
Sbjct: 42 QPLGLLLKQDPLVAHLALYDVVNTPGVAADLSHIDSNAKVTAHTGPKELYAAVENADVIV 101
Query: 181 IPAGVPRKPGMTRDDLFNTNASIVADLVHGCAQACPKAIICIITNPVNSTVPIAAEILKK 360
IPAGVPRKPGMTRDDLFNTNA IV DL A+A PKA+I IITNPVNSTVPIA+E+LKK
Sbjct: 102 IPAGVPRKPGMTRDDLFNTNAGIVRDLAAVIAKASPKALIAIITNPVNSTVPIASEVLKK 161
Query: 361 AGCYDPKRLFGVTTLDIVRSNTFISEAKHLDVTKMPVPVIGGHSGVTIVPVISQAIPSVS 540
AG YDPKR+FGVTTLD+VRS F+SE K D +K VPV+GGH+G+TI+P++SQ PS
Sbjct: 162 AGVYDPKRVFGVTTLDVVRSQAFVSELKGHDASKTVVPVVGGHAGITIIPLLSQVKPSTK 221
Query: 541 FPESEISKLTIRIQNAGTEVVEAKAGAGSATLSMAYAGVRFVKRILAAMKGNKNI 705
F E EISKLT RIQ+AGTEVV AKAGAGSATLSMA AG RF ++ +KG KN+
Sbjct: 222 FSEEEISKLTPRIQDAGTEVVNAKAGAGSATLSMALAGARFANALVRGIKGEKNV 276
>sp|O82399|MDHI_ARATH Probable malate dehydrogenase, glyoxysomal precursor
Length = 354
Score = 287 bits (735), Expect = 2e-77
Identities = 143/235 (60%), Positives = 178/235 (75%)
Frame = +1
Query: 1 QPMSLLLKKSSAVDRLALYDIAHVKGVAADLSHIETPAVVNGYLGPSELLECLKNSDVVV 180
QP+++L+K + V L LYD+A+ GV AD+SH++T AVV G+LG +L E L D+V+
Sbjct: 56 QPLAMLMKMNPLVSVLHLYDVANAPGVTADISHMDTSAVVRGFLGQPQLEEALTGMDLVI 115
Query: 181 IPAGVPRKPGMTRDDLFNTNASIVADLVHGCAQACPKAIICIITNPVNSTVPIAAEILKK 360
IPAGVPRKPGMTRDDLFN NA IV L A+ CPKAI+ II+NPVNSTVPIAAE+ KK
Sbjct: 116 IPAGVPRKPGMTRDDLFNINAGIVRTLSEAIAKCCPKAIVNIISNPVNSTVPIAAEVFKK 175
Query: 361 AGCYDPKRLFGVTTLDIVRSNTFISEAKHLDVTKMPVPVIGGHSGVTIVPVISQAIPSVS 540
AG +DPK+L GVT LD+VR+NTF++E LD ++ VPV+GGH+GVTI+P++SQ P S
Sbjct: 176 AGTFDPKKLMGVTMLDVVRANTFVAEVMSLDpreVEVPVVGGHAGVTILPLLSQVKPPCS 235
Query: 541 FPESEISKLTIRIQNAGTEVVEAKAGAGSATLSMAYAGVRFVKRILAAMKGNKNI 705
F + EI LT RIQN GTEVVEAKAGAGSATLSMAYA V F L ++G+ NI
Sbjct: 236 FTQKEIEYLTDRIQNGGTEVVEAKAGAGSATLSMAYAAVEFADACLRGLRGDANI 290
Score = 31.2 bits (69), Expect = 3.6
Identities = 13/23 (56%), Positives = 18/23 (78%)
Frame = +2
Query: 707 VECAFVESNITEAKFFANPLLLG 775
VECA+V S++TE FFA+ + LG
Sbjct: 291 VECAYVASHVTELPFFASKVRLG 313
>sp|Q42972|MDHG_ORYSA Malate dehydrogenase, glyoxysomal precursor
Length = 356
Score = 285 bits (729), Expect = 1e-76
Identities = 144/235 (61%), Positives = 174/235 (74%)
Frame = +1
Query: 1 QPMSLLLKKSSAVDRLALYDIAHVKGVAADLSHIETPAVVNGYLGPSELLECLKNSDVVV 180
QP++LL+K + V L LYD+ + GV AD+SH+ T AVV G+LG +L L D+V+
Sbjct: 58 QPLALLMKMNPLVSVLHLYDVVNTPGVTADISHMNTGAVVRGFLGQPQLENALTGMDLVI 117
Query: 181 IPAGVPRKPGMTRDDLFNTNASIVADLVHGCAQACPKAIICIITNPVNSTVPIAAEILKK 360
IPAGVPRKPGMTRDDLFN NA IV L G A+ CP AI+ +I+NPVNSTVPIAAE+ KK
Sbjct: 118 IPAGVPRKPGMTRDDLFNINAGIVRTLCEGIAKCCPNAIVNVISNPVNSTVPIAAEVFKK 177
Query: 361 AGCYDPKRLFGVTTLDIVRSNTFISEAKHLDVTKMPVPVIGGHSGVTIVPVISQAIPSVS 540
AG YDPKRL GVTTLD+VR+NTF++E LD + VPVIGGH+GVTI+P++SQ P S
Sbjct: 178 AGTYDPKRLLGVTTLDVVRANTFVAEVLGLDPRDVNVPVIGGHAGVTILPLLSQVNPPCS 237
Query: 541 FPESEISKLTIRIQNAGTEVVEAKAGAGSATLSMAYAGVRFVKRILAAMKGNKNI 705
F EIS LT RIQN GTEVVEAKAGAGSATLSMAYA +F L ++G+ I
Sbjct: 238 FTSEEISYLTTRIQNGGTEVVEAKAGAGSATLSMAYAASKFADACLRGLRGDAGI 292
Score = 30.8 bits (68), Expect = 4.6
Identities = 13/23 (56%), Positives = 17/23 (73%)
Frame = +2
Query: 707 VECAFVESNITEAKFFANPLLLG 775
VEC+FV S +TE FFA+ + LG
Sbjct: 293 VECSFVASQVTELPFFASKVRLG 315
>sp|P19446|MDHG_CITLA Malate dehydrogenase, glyoxysomal precursor
Length = 356
Score = 281 bits (720), Expect = 1e-75
Identities = 138/235 (58%), Positives = 176/235 (74%)
Frame = +1
Query: 1 QPMSLLLKKSSAVDRLALYDIAHVKGVAADLSHIETPAVVNGYLGPSELLECLKNSDVVV 180
QP+++L+K + V L LYD+ + GV AD+SH++T AVV G+LG +L L D+++
Sbjct: 58 QPLAMLMKMNPLVSVLHLYDVVNAPGVTADISHMDTGAVVRGFLGQQQLEAALTGMDLII 117
Query: 181 IPAGVPRKPGMTRDDLFNTNASIVADLVHGCAQACPKAIICIITNPVNSTVPIAAEILKK 360
+PAGVPRKPGMTRDDLF NA IV L G A+ CP+AI+ +I+NPVNSTVPIAAE+ KK
Sbjct: 118 VPAGVPRKPGMTRDDLFKINAGIVKTLCEGIAKCCPRAIVNLISNPVNSTVPIAAEVFKK 177
Query: 361 AGCYDPKRLFGVTTLDIVRSNTFISEAKHLDVTKMPVPVIGGHSGVTIVPVISQAIPSVS 540
AG YDPKRL GVT LD+VR+NTF++E LD + VPV+GGH+GVTI+P++SQ P S
Sbjct: 178 AGTYDPKRLLGVTMLDVVRANTFVAEVLGLDPRDVDVPVVGGHAGVTILPLLSQVKPPSS 237
Query: 541 FPESEISKLTIRIQNAGTEVVEAKAGAGSATLSMAYAGVRFVKRILAAMKGNKNI 705
F + EIS LT RIQN GTEVVEAKAGAGSATLSMAYA V+F L ++G+ +
Sbjct: 238 FTQEEISYLTDRIQNGGTEVVEAKAGAGSATLSMAYAAVKFADACLRGLRGDAGV 292
Score = 32.0 bits (71), Expect = 2.1
Identities = 13/23 (56%), Positives = 17/23 (73%)
Frame = +2
Query: 707 VECAFVESNITEAKFFANPLLLG 775
+ECAFV S +TE FFA+ + LG
Sbjct: 293 IECAFVSSQVTELPFFASKVRLG 315
>sp|P46488|MDHG_CUCSA Malate dehydrogenase, glyoxysomal precursor
Length = 356
Score = 280 bits (717), Expect = 3e-75
Identities = 140/235 (59%), Positives = 175/235 (74%)
Frame = +1
Query: 1 QPMSLLLKKSSAVDRLALYDIAHVKGVAADLSHIETPAVVNGYLGPSELLECLKNSDVVV 180
QP+++L+K + V L LYD+ + GV AD+SH++T AVV G+LG +L L D+VV
Sbjct: 58 QPLAMLMKMNPLVSVLHLYDVVNAPGVTADISHMDTGAVVRGFLGQQQLERALTGMDLVV 117
Query: 181 IPAGVPRKPGMTRDDLFNTNASIVADLVHGCAQACPKAIICIITNPVNSTVPIAAEILKK 360
IPAGVPRKPGMTRDDLF NA IV L G A+ CP AI+ +I+NPVNSTVPIAAE+ KK
Sbjct: 118 IPAGVPRKPGMTRDDLFKINAGIVKTLCEGIAKCCPTAIVNLISNPVNSTVPIAAEVFKK 177
Query: 361 AGCYDPKRLFGVTTLDIVRSNTFISEAKHLDVTKMPVPVIGGHSGVTIVPVISQAIPSVS 540
AG YDPKRL GVT LD+VR+NTF++E LD + VPV+GGH+GVTI+P++SQ P S
Sbjct: 178 AGTYDPKRLLGVTMLDVVRANTFVAEVLGLDPRDVNVPVVGGHAGVTILPLLSQVKPPSS 237
Query: 541 FPESEISKLTIRIQNAGTEVVEAKAGAGSATLSMAYAGVRFVKRILAAMKGNKNI 705
F + EI+ LT RIQN GTEVVEAKAGAGSATLSMAYA V+F L ++G+ +
Sbjct: 238 FTQEEINYLTDRIQNGGTEVVEAKAGAGSATLSMAYAAVKFADACLRGLRGDAGV 292
Score = 32.0 bits (71), Expect = 2.1
Identities = 14/23 (60%), Positives = 16/23 (69%)
Frame = +2
Query: 707 VECAFVESNITEAKFFANPLLLG 775
VECAFV S +TE FFA + LG
Sbjct: 293 VECAFVSSQVTELPFFATKVRLG 315
>sp|Q9ZP05|MDHG_ARATH Malate dehydrogenase, glyoxysomal precursor (mbNAD-MDH)
Length = 354
Score = 280 bits (715), Expect = 4e-75
Identities = 138/235 (58%), Positives = 174/235 (74%)
Frame = +1
Query: 1 QPMSLLLKKSSAVDRLALYDIAHVKGVAADLSHIETPAVVNGYLGPSELLECLKNSDVVV 180
Q +SLL+K + V L LYD+ + GV AD+SH++T AVV G+LG +L + L D+V+
Sbjct: 56 QSLSLLMKMNPLVSLLHLYDVVNAPGVTADVSHMDTGAVVRGFLGAKQLEDALTGMDLVI 115
Query: 181 IPAGVPRKPGMTRDDLFNTNASIVADLVHGCAQACPKAIICIITNPVNSTVPIAAEILKK 360
IPAG+PRKPGMTRDDLF NA IV L G A+ CP AI+ +I+NPVNSTVPIAAE+ KK
Sbjct: 116 IPAGIPRKPGMTRDDLFKINAGIVKTLCEGVAKCCPNAIVNLISNPVNSTVPIAAEVFKK 175
Query: 361 AGCYDPKRLFGVTTLDIVRSNTFISEAKHLDVTKMPVPVIGGHSGVTIVPVISQAIPSVS 540
AG YDPK+L GVTTLD+ R+NTF++E LD ++ VPV+GGH+GVTI+P++SQ P S
Sbjct: 176 AGTYDPKKLLGVTTLDVARANTFVAEVLGLDpreVDVPVVGGHAGVTILPLLSQVKPPSS 235
Query: 541 FPESEISKLTIRIQNAGTEVVEAKAGAGSATLSMAYAGVRFVKRILAAMKGNKNI 705
F EI LT RIQN GTEVVEAKAGAGSATLSMAYA +F L ++G+ N+
Sbjct: 236 FTPQEIEYLTNRIQNGGTEVVEAKAGAGSATLSMAYAAAKFADACLRGLRGDANV 290
Score = 30.4 bits (67), Expect = 6.1
Identities = 13/23 (56%), Positives = 16/23 (69%)
Frame = +2
Query: 707 VECAFVESNITEAKFFANPLLLG 775
VEC+FV S +TE FFA + LG
Sbjct: 291 VECSFVASQVTELAFFATKVRLG 313
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 92,918,893
Number of Sequences: 369166
Number of extensions: 1925466
Number of successful extensions: 5791
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5400
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5643
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 7811456130
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)