Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_007_M08
(829 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q7T019|DZP1_BRARE Zinc finger protein Dzip1 (DAZ-interac... 54 5e-07
sp|Q86YF9|DZIP1_HUMAN Zinc finger protein DZIP1 (DAZ-intera... 47 5e-05
sp|Q8BMD2|DZIP1_MOUSE Zinc finger protein DZIP1 (DAZ-intera... 45 2e-04
sp|Q96YR5|RAD50_SULTO DNA double-strand break repair rad50 ... 43 0.001
sp|O95819|M4K4_HUMAN Mitogen-activated protein kinase kinas... 43 0.001
sp|Q9FLH0|NMCP_ARATH Putative nuclear matrix constituent pr... 42 0.002
sp|Q9JIX8|ACINU_MOUSE Apoptotic chromatin condensation indu... 42 0.002
sp|P15924|DESP_HUMAN Desmoplakin (DP) (250/210 kDa paraneop... 40 0.008
sp|Q09863|YAFA_SCHPO Hypothetical protein C29E6.10c in chro... 40 0.010
sp|Q14151|SAFB2_HUMAN Scaffold attachment factor B2 39 0.017
>sp|Q7T019|DZP1_BRARE Zinc finger protein Dzip1 (DAZ-interacting protein 1 homolog)
(Iguana protein)
Length = 898
Score = 53.9 bits (128), Expect = 5e-07
Identities = 37/146 (25%), Positives = 73/146 (50%), Gaps = 2/146 (1%)
Frame = +2
Query: 2 CPYCEKAFLNGTFLQAHLEKRHADRYIKDWYLIENQRKRSPKREHSEERPAEKDKTLELI 181
C +CEKAF+N +FLQ+H+++RH + + +NQ+K + E ++ L L+
Sbjct: 209 CQHCEKAFMNASFLQSHMQRRHPSEFDMK-LMTDNQKKIQTVKLQDEINKLQEQ--LTLV 265
Query: 182 LQKLMEQRKGSPVQQKNYDDDLRRMLSEFDRERREW-QLQMDRLKDEIEKLRHQLWLANQ 358
++ Q+K +Q + +L + EF R+ W + + R+ +I++++
Sbjct: 266 TSQMETQQKDYTAKQ---EKELIQRQEEFKRQLEIWKEEEKMRMNSKIDEVKQACQRDMD 322
Query: 359 KPRSHLKNLEDD-LDHEQDNIERARQ 433
+NLE + L +Q NI+ + Q
Sbjct: 323 SINQRNRNLETELLKLQQKNIQESMQ 348
>sp|Q86YF9|DZIP1_HUMAN Zinc finger protein DZIP1 (DAZ-interacting protein 1/2)
Length = 867
Score = 47.4 bits (111), Expect = 5e-05
Identities = 38/155 (24%), Positives = 71/155 (45%), Gaps = 10/155 (6%)
Frame = +2
Query: 2 CPYCEKAFLNGTFLQAHLEKRHADRYIKDWYLIENQRKRSPKREHSEERPAE---KDKTL 172
C +C+KAF+N FLQ+H+++RH + EN K E+ +E + L
Sbjct: 200 CHFCDKAFMNQAFLQSHIQRRHTE---------ENSHFEYQKNAQIEKLRSEIVVLKEEL 250
Query: 173 ELILQKLMEQRKGSPVQ-------QKNYDDDLRRMLSEFDRERREWQLQMDRLKDEIEKL 331
+L +L S V+ QK ++D ++ FDR + E + ++L DE+EK+
Sbjct: 251 QLTRSELEAAHHASAVRFSKEYEMQKTKEEDFLKL---FDRWKEE---EKEKLVDEMEKV 304
Query: 332 RHQLWLANQKPRSHLKNLEDDLDHEQDNIERARQK 436
+ K L + L+++ I+++ +
Sbjct: 305 KEMF----MKEFKELTSKNSALEYQLSEIQKSNMQ 335
>sp|Q8BMD2|DZIP1_MOUSE Zinc finger protein DZIP1 (DAZ-interacting protein 1 homolog)
Length = 852
Score = 45.4 bits (106), Expect = 2e-04
Identities = 31/118 (26%), Positives = 64/118 (54%), Gaps = 7/118 (5%)
Frame = +2
Query: 2 CPYCEKAFLNGTFLQAHLEKRHADRYIKDWYLIENQRKRSPKREHSEERPAEKDKTLELI 181
C +C+KAF+N FLQ+H+++RH + D +L N + ++ + + + E+ L+L
Sbjct: 185 CHFCDKAFMNQAFLQSHIQRRHTE----DSHLEYNTKAQTDRLQKEIDMLKEQ---LQLT 237
Query: 182 LQKLMEQRKGSPVQ-------QKNYDDDLRRMLSEFDRERREWQLQMDRLKDEIEKLR 334
+L + V+ QK+ ++D ++ FDR + E + ++L +E+EK++
Sbjct: 238 RSQLESAQHSHAVRFSKDYEMQKSKEEDFLKL---FDRWKEE---EKEKLLEEMEKVK 289
>sp|Q96YR5|RAD50_SULTO DNA double-strand break repair rad50 ATPase
Length = 879
Score = 43.1 bits (100), Expect = 0.001
Identities = 35/119 (29%), Positives = 65/119 (54%), Gaps = 2/119 (1%)
Frame = +2
Query: 95 LIENQRKRSPKREHSEERPAEKDKTLELILQKLMEQRKGSPVQQKNYDDDLRRMLSEFDR 274
+IE Q K E SE + +K+K LE I ++L + ++K Y+D ++ E +
Sbjct: 183 IIELQSLEKYKNE-SENQKIQKEKELENIKRELEDLNIKEEKERKKYEDIVKLNEEEEKK 241
Query: 275 ERREWQL--QMDRLKDEIEKLRHQLWLANQKPRSHLKNLEDDLDHEQDNIERARQKAID 445
E+R +L +++LKD+I +LR ++ N + R + LE D+ E+D + ++K I+
Sbjct: 242 EKRYVELISLLNKLKDDISELREEVKDEN-RLREEKEKLEKDI-LEKDKLIEEKEKIIE 298
>sp|O95819|M4K4_HUMAN Mitogen-activated protein kinase kinase kinase kinase 4 (MAPK/ERK
kinase kinase kinase 4) (MEK kinase kinase 4) (MEKKK 4)
(HPK/GCK-like kinase HGK) (Nck interacting kinase)
Length = 1239
Score = 42.7 bits (99), Expect = 0.001
Identities = 36/157 (22%), Positives = 72/157 (45%), Gaps = 15/157 (9%)
Frame = +2
Query: 26 LNGTFLQAHLEKRHADRYIKDWYLIENQRKRSPK---------REHSEERPAEKDKTLEL 178
L FL+ E + ++ L++ Q+ R + R+ E+ E+ + LE
Sbjct: 352 LRRDFLRLQQENKERSEALRRQQLLQEQQLREQEEYKRQLLAERQKRIEQQKEQRRRLEE 411
Query: 179 ILQKLMEQRKGSPVQQKNYDDDLRRMLSEFDR------ERREWQLQMDRLKDEIEKLRHQ 340
++ E R+ +Q+ + + +R L E +R ERR + + R++ E E +R Q
Sbjct: 412 QQRREREARRQQEREQRRREQEEKRRLEELERRRKEEEERRRAEEEKRRVEREQEYIRRQ 471
Query: 341 LWLANQKPRSHLKNLEDDLDHEQDNIERARQKAIDDH 451
L ++ + HL+ L+ L EQ + R + +++H
Sbjct: 472 L----EEEQRHLEVLQQQLLQEQAMLLECRWREMEEH 504
>sp|Q9FLH0|NMCP_ARATH Putative nuclear matrix constituent protein 1-like protein
(NMCP1-like)
Length = 1042
Score = 42.4 bits (98), Expect = 0.002
Identities = 36/124 (29%), Positives = 62/124 (50%), Gaps = 5/124 (4%)
Frame = +2
Query: 92 YLIENQRKRSPKREHSEERPAEKDKTLE---LILQKLMEQRKGSPVQQKNYDDDLRRMLS 262
Y IEN+R+ E+ E++K LE + K M +++ VQ + D R+
Sbjct: 657 YCIENKREELENSSRDREKAFEQEKKLEEERIQSLKEMAEKELEHVQVELKRLDAERLEI 716
Query: 263 EFDRERREWQLQMDRLKDEIEKLRHQLWLANQKPRSHLKNLEDDLDHEQDNIERAR--QK 436
+ DRERRE + LKD +E+L+ Q + R L+ D++ HE + +++ +
Sbjct: 717 KLDRERRE--REWAELKDSVEELKVQREKL-ETQRHMLRAERDEIRHEIEELKKLENLKV 773
Query: 437 AIDD 448
A+DD
Sbjct: 774 ALDD 777
>sp|Q9JIX8|ACINU_MOUSE Apoptotic chromatin condensation inducer in the nucleus (Acinus)
Length = 1338
Score = 42.0 bits (97), Expect = 0.002
Identities = 33/126 (26%), Positives = 57/126 (45%), Gaps = 11/126 (8%)
Frame = +2
Query: 101 ENQRKRSPKREHSEERPAEKDKTLELILQKLMEQRKGSP-----------VQQKNYDDDL 247
+++ K+S K+E ++E P K +L L + K +P + QK +
Sbjct: 1189 KSKEKKSEKKEKAQEEPPAK------LLDDLFRKTKAAPCIYWLPLTESQIVQKEAEQAE 1242
Query: 248 RRMLSEFDRERREWQLQMDRLKDEIEKLRHQLWLANQKPRSHLKNLEDDLDHEQDNIERA 427
R E R+ RE + Q +R K+ + QL +K R H + E D + E+D +R
Sbjct: 1243 RAKEREKRRKEREEEEQKEREKEAERERNRQL--EREKRREHSRERERDRERERDRGDRE 1300
Query: 428 RQKAID 445
R++ D
Sbjct: 1301 RERERD 1306
>sp|P15924|DESP_HUMAN Desmoplakin (DP) (250/210 kDa paraneoplastic pemphigus antigen)
Length = 2871
Score = 40.0 bits (92), Expect = 0.008
Identities = 31/118 (26%), Positives = 57/118 (48%), Gaps = 12/118 (10%)
Frame = +2
Query: 104 NQRKRSPKREHSEERPAEKD--------KTLELILQKLMEQRKGSPVQQKNYDDDLRRML 259
N+ KR+ + + + E++ K + + L +Q + + + +K +DDLR+
Sbjct: 1578 NRLKRTASEDSCKRKKLEEELEGMRRSLKEQAIKITNLTQQLEQASIVKKRSEDDLRQQR 1637
Query: 260 SEFD---RERREWQLQMDRLKDEIEKLRHQLWLANQK-PRSHLKNLEDDLDHEQDNIE 421
D RE++ Q ++ RL E+E LR QL + ++HL+N +H Q IE
Sbjct: 1638 DVLDGHLREKQRTQEELRRLSSEVEALRRQLLQEQESVKQAHLRN-----EHFQKAIE 1690
>sp|Q09863|YAFA_SCHPO Hypothetical protein C29E6.10c in chromosome I
Length = 1085
Score = 39.7 bits (91), Expect = 0.010
Identities = 37/134 (27%), Positives = 63/134 (47%), Gaps = 4/134 (2%)
Frame = +2
Query: 41 LQAHLEKRHADRYIKDWYLIE--NQRKRSP--KREHSEERPAEKDKTLELILQKLMEQRK 208
LQA+ EK R K IE N+RK+ K+ +E+ +K K L+L ++ ++R+
Sbjct: 557 LQAYREKVAQQRQAKLLEEIEEENKRKQERELKKIREKEKKRDKKKQLKLAKEEERQRRE 616
Query: 209 GSPVQQKNYDDDLRRMLSEFDRERREWQLQMDRLKDEIEKLRHQLWLANQKPRSHLKNLE 388
+ ++ L E R++RE Q RLK E EK + +L ++ + K E
Sbjct: 617 AERLAEQAAQKALEAKRQEEARKKREEQ----RLKREQEKKQQELERQKREEKQKQKERE 672
Query: 389 DDLDHEQDNIERAR 430
L +Q +R +
Sbjct: 673 KKLKKQQQEADREK 686
Score = 34.3 bits (77), Expect = 0.43
Identities = 33/152 (21%), Positives = 71/152 (46%), Gaps = 23/152 (15%)
Frame = +2
Query: 59 KRHADRYIKDWYLIENQRKRSPKRE-----HSEERPAEKDKTLELILQKLMEQRKGSPVQ 223
KR +R +K + E ++KR K++ E + E ++ E QK +E ++ +
Sbjct: 581 KRKQERELKK--IREKEKKRDKKKQLKLAKEEERQRREAERLAEQAAQKALEAKRQEEAR 638
Query: 224 QKNYDDDLRR----MLSEFDRERREWQLQMDRLKDEIEKLRHQLWLANQKPRSHLKNLED 391
+K + L+R E +R++RE + + K+ +KL+ Q A+++ + + L +
Sbjct: 639 KKREEQRLKREQEKKQQELERQKRE---EKQKQKEREKKLKKQQQEADREKMAREQRLRE 695
Query: 392 D--------------LDHEQDNIERARQKAID 445
+ LD E++ ER R++ ++
Sbjct: 696 EEEKRILEERKRREKLDKEEE--ERRRRELLE 725
Score = 31.6 bits (70), Expect = 2.8
Identities = 24/103 (23%), Positives = 49/103 (47%), Gaps = 1/103 (0%)
Frame = +2
Query: 140 EERPAEKDKTLELILQKLMEQRKGSPVQQKNYDDDLRRMLSEFDRERREWQLQMDRLKDE 319
E+R E + ++ +L EQR ++K ++L E + E + Q + E
Sbjct: 534 EQRMEEGRRMFQIFAARLFEQRVLQAYREKVAQQRQAKLLEEIEEENKRKQ------ERE 587
Query: 320 IEKLRHQLWLANQKPRSHLKNLEDDLDHEQDNI-ERARQKAID 445
++K+R + ++K + L E+ E + + E+A QKA++
Sbjct: 588 LKKIREKEKKRDKKKQLKLAKEEERQRREAERLAEQAAQKALE 630
>sp|Q14151|SAFB2_HUMAN Scaffold attachment factor B2
Length = 953
Score = 38.9 bits (89), Expect = 0.017
Identities = 34/114 (29%), Positives = 62/114 (54%), Gaps = 5/114 (4%)
Frame = +2
Query: 110 RKRSPKREHSEERPAE-KDKTLELILQKLMEQRKGSPVQQKNYDDDLRRMLSEFDRERRE 286
++RS K S++R +E K+K L K+ EQR+ +Q+ + ++R +RE+RE
Sbjct: 592 KERSSK---SQDRKSESKEKRDILSFDKIKEQRERE--RQRQREREIRETERRREREQRE 646
Query: 287 WQLQMDRLKDEIEKLRHQ---LWLANQKPRSHLKNLE-DDLDHEQDNIERARQK 436
+ +++ + EK R Q L L Q+ R + +E + L+ E+ +ER R+K
Sbjct: 647 REQRLEAFHERKEKARLQRERLQLECQRQRLERERMERERLERERMRVERERRK 700
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 85,281,024
Number of Sequences: 369166
Number of extensions: 1590323
Number of successful extensions: 7242
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 6286
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 7160
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 8004331590
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)