Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_007_M07
(663 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9DC61|MPPA_MOUSE Mitochondrial processing peptidase alp... 117 4e-26
sp|P20069|MPPA_RAT Mitochondrial processing peptidase alpha... 115 8e-26
sp|Q10713|MPPA_HUMAN Mitochondrial processing peptidase alp... 115 1e-25
sp|P97997|MPPA_BLAEM Mitochondrial processing peptidase alp... 108 2e-23
sp|O94745|MPPA_SCHPO Probable mitochondrial processing pept... 98 2e-20
sp|P23955|MPPA_NEUCR Mitochondrial processing peptidase alp... 98 2e-20
sp|P11914|MPPA_YEAST Mitochondrial processing peptidase alp... 97 3e-20
sp|Q9ZU25|MPPA1_ARATH Probable mitochondrial processing pep... 93 7e-19
sp|P29677|MPPA_SOLTU Mitochondrial processing peptidase alp... 90 6e-18
sp|O04308|MPPA2_ARATH Probable mitochondrial processing pep... 83 7e-16
>sp|Q9DC61|MPPA_MOUSE Mitochondrial processing peptidase alpha subunit, mitochondrial
precursor (Alpha-MPP) (P-55)
Length = 524
Score = 117 bits (292), Expect = 4e-26
Identities = 64/191 (33%), Positives = 100/191 (52%)
Frame = +3
Query: 3 FVHACLLQTLMXXXXXXXXXXXXXXMFSRLYKEVLHKYPWVNSVVAMNHSYSDTGLFTIT 182
F+ +L +M MFSRLY VL+++ W+ + + +HSY DTGL I
Sbjct: 333 FIPFAVLNMMMGGGGSFSAGGPGKGMFSRLYLNVLNRHHWMYNATSYHHSYEDTGLLCIH 392
Query: 183 GSSVPGNLDTLALVLAHQLKNMVKSIDKEDFARAKCQLKSMLLMNLETRAVVFEDIGRQV 362
S+ P + + ++ + M +++D + RAK QL SML+MNLE+R V+FED+GRQV
Sbjct: 393 ASADPRQVREMVEIITKEFILMGRTVDLVELERAKTQLMSMLMMNLESRPVIFEDVGRQV 452
Query: 363 IYQGHRNSADYWVEQIDKATEQEVRDFAQRMLLSRPAIAGFGKLEKLQSLEVITKLLEIS 542
+ R I ++++ A +ML +PA+A G L L + E I L
Sbjct: 453 LATHSRKLPHELCTLIRNVKPEDIKRVASKMLRGKPAVAALGDLTDLPTYEHIQAALSSR 512
Query: 543 EGFIPKSFRKF 575
G +P+S+R F
Sbjct: 513 NGHLPRSYRLF 523
>sp|P20069|MPPA_RAT Mitochondrial processing peptidase alpha subunit, mitochondrial
precursor (Alpha-MPP) (P-55)
Length = 524
Score = 115 bits (289), Expect = 8e-26
Identities = 63/191 (32%), Positives = 101/191 (52%)
Frame = +3
Query: 3 FVHACLLQTLMXXXXXXXXXXXXXXMFSRLYKEVLHKYPWVNSVVAMNHSYSDTGLFTIT 182
F+ +L +M MFSRLY VL+++ W+ + + +HSY DTGL I
Sbjct: 333 FIPFAVLNMMMGGGGSFSAGGPGKGMFSRLYLNVLNRHHWMYNATSYHHSYEDTGLLCIH 392
Query: 183 GSSVPGNLDTLALVLAHQLKNMVKSIDKEDFARAKCQLKSMLLMNLETRAVVFEDIGRQV 362
S+ P + + ++ + M +++D + RAK QL SML+MNLE+R V+FED+GRQV
Sbjct: 393 ASADPRQVREMVEIITKEFILMGRTVDLVELERAKTQLMSMLMMNLESRPVIFEDVGRQV 452
Query: 363 IYQGHRNSADYWVEQIDKATEQEVRDFAQRMLLSRPAIAGFGKLEKLQSLEVITKLLEIS 542
+ R I ++++ A +ML +PA+A G L L + E I L
Sbjct: 453 LATHSRKLPHELCTLIRNVKPEDIKRVASKMLRGKPAVAALGDLTDLPTYEHIQAALSSR 512
Query: 543 EGFIPKSFRKF 575
+G +P+++R F
Sbjct: 513 DGRLPRTYRLF 523
>sp|Q10713|MPPA_HUMAN Mitochondrial processing peptidase alpha subunit, mitochondrial
precursor (Alpha-MPP) (P-55) (HA1523)
Length = 525
Score = 115 bits (288), Expect = 1e-25
Identities = 64/191 (33%), Positives = 100/191 (52%)
Frame = +3
Query: 3 FVHACLLQTLMXXXXXXXXXXXXXXMFSRLYKEVLHKYPWVNSVVAMNHSYSDTGLFTIT 182
F+ +L +M MFSRLY VL+++ W+ + + +HSY DTGL I
Sbjct: 334 FIPFAVLNMMMGGGGSFSAGGPGKGMFSRLYLNVLNRHHWMYNATSYHHSYEDTGLLCIH 393
Query: 183 GSSVPGNLDTLALVLAHQLKNMVKSIDKEDFARAKCQLKSMLLMNLETRAVVFEDIGRQV 362
S+ P + + ++ + M ++D + RAK QL SML+MNLE+R V+FED+GRQV
Sbjct: 394 ASADPRQVREMVEIITKEFILMGGTVDTVELERAKTQLTSMLMMNLESRPVIFEDVGRQV 453
Query: 363 IYQGHRNSADYWVEQIDKATEQEVRDFAQRMLLSRPAIAGFGKLEKLQSLEVITKLLEIS 542
+ R I ++V+ A +ML +PA+A G L L + E I L
Sbjct: 454 LATRSRKLPHELCTLIRNVKPEDVKRVASKMLRGKPAVAALGDLTDLPTYEHIQTALSSK 513
Query: 543 EGFIPKSFRKF 575
+G +P+++R F
Sbjct: 514 DGRLPRTYRLF 524
>sp|P97997|MPPA_BLAEM Mitochondrial processing peptidase alpha subunit, mitochondrial
precursor (Alpha-MPP)
Length = 474
Score = 108 bits (269), Expect = 2e-23
Identities = 66/175 (37%), Positives = 90/175 (51%)
Frame = +3
Query: 21 LQTLMXXXXXXXXXXXXXXMFSRLYKEVLHKYPWVNSVVAMNHSYSDTGLFTITGSSVPG 200
LQ LM M+SRLY VL++Y W+ S A H+YS T LF I+ S VP
Sbjct: 282 LQVLMGGGGAFSAGGPGKGMYSRLYTNVLNRYRWMESCAAFQHAYSSTSLFGISASCVPS 341
Query: 201 NLDTLALVLAHQLKNMVKSIDKEDFARAKCQLKSMLLMNLETRAVVFEDIGRQVIYQGHR 380
L VLA + +M +++ E+ ARAK QLKS LLMNLE++ + EDIGRQV+ Q R
Sbjct: 342 FNPHLCNVLAGEFVHMARNLSDEEVARAKNQLKSSLLMNLESQVITVEDIGRQVLAQNQR 401
Query: 381 NSADYWVEQIDKATEQEVRDFAQRMLLSRPAIAGFGKLEKLQSLEVITKLLEISE 545
V I T ++ A+ ++ P + G E +TKL +I E
Sbjct: 402 LEPLELVNNISAVTRDDLVRVAEALVAKPPTMVAVG--------EDLTKLTDIKE 448
>sp|O94745|MPPA_SCHPO Probable mitochondrial processing peptidase alpha subunit,
mitochondrial precursor (Alpha-MPP)
Length = 494
Score = 97.8 bits (242), Expect = 2e-20
Identities = 56/138 (40%), Positives = 83/138 (60%), Gaps = 1/138 (0%)
Frame = +3
Query: 78 MFSRLYKEVLHKYPWVNSVVAMNHSYSDTGLFTITGSSVPGNLDTLALVLAHQLKNMVKS 257
M+SRLY VL++YPWV + +A NHSY+D+GLF + + + A ++ +L N V S
Sbjct: 328 MYSRLYLNVLNQYPWVETCMAFNHSYTDSGLFGMFVTILDDAAHLAAPLIIRELCNTVLS 387
Query: 258 IDKEDFARAKCQLKSMLLMNLETRAVVFEDIGRQVIYQ-GHRNSADYWVEQIDKATEQEV 434
+ E+ RAK QLKS LLMNLE+R + ED+GRQ+ Q G + +E+ID T ++
Sbjct: 388 VTSEETERAKNQLKSSLLMNLESRMISLEDLGRQIQTQNGLYITPKEMIEKIDALTPSDL 447
Query: 435 RDFAQRMLLSRPAIAGFG 488
A+R+L + G G
Sbjct: 448 SRVARRVLTGNVSNPGNG 465
>sp|P23955|MPPA_NEUCR Mitochondrial processing peptidase alpha subunit, mitochondrial
precursor (Alpha-MPP)
Length = 577
Score = 97.8 bits (242), Expect = 2e-20
Identities = 59/161 (36%), Positives = 88/161 (54%), Gaps = 5/161 (3%)
Frame = +3
Query: 21 LQTLMXXXXXXXXXXXXXXMFSRLYKEVLHKYPWVNSVVAMNHSYSDTGLFTITGSSVPG 200
LQTL+ M+SRLY VL+++ WV S VA NHSY+D+GLF I S PG
Sbjct: 379 LQTLLGGGGSFSAGGPGKGMYSRLYTNVLNQHGWVESCVAFNHSYTDSGLFGIAASCYPG 438
Query: 201 NLDTLALVLAHQLKNMV-----KSIDKEDFARAKCQLKSMLLMNLETRAVVFEDIGRQVI 365
+ V+ +L + ++ + + +RAK QL+S LLMNLE+R V ED+GRQV
Sbjct: 439 RTLPMLQVMCRELHALTTDHGYSALGELEVSRAKNQLRSSLLMNLESRMVELEDLGRQVQ 498
Query: 366 YQGHRNSADYWVEQIDKATEQEVRDFAQRMLLSRPAIAGFG 488
G + +I++ T +++R A+R++ AG G
Sbjct: 499 VHGRKIPVREMTRRINELTVKDLRRVAKRVVGGMANNAGQG 539
>sp|P11914|MPPA_YEAST Mitochondrial processing peptidase alpha subunit, mitochondrial
precursor (Alpha-MPP)
Length = 482
Score = 97.4 bits (241), Expect = 3e-20
Identities = 58/161 (36%), Positives = 88/161 (54%), Gaps = 4/161 (2%)
Frame = +3
Query: 21 LQTLMXXXXXXXXXXXXXXMFSRLYKEVLHKYPWVNSVVAMNHSYSDTGLFTITGSSVPG 200
LQTL+ M+SRLY VL++Y +V + VA NHSYSD+G+F I+ S +P
Sbjct: 279 LQTLLGGGGSFSAGGPGKGMYSRLYTHVLNQYYFVENCVAFNHSYSDSGIFGISLSCIPQ 338
Query: 201 NLDTLALVLAHQLKNMVKSID----KEDFARAKCQLKSMLLMNLETRAVVFEDIGRQVIY 368
V+A Q+ N + D +++ +RAK QLKS LLMNLE++ V ED+GRQV+
Sbjct: 339 AAPQAVEVIAQQMYNTFANKDLRLTEDEVSRAKNQLKSSLLMNLESKLVELEDMGRQVLM 398
Query: 369 QGHRNSADYWVEQIDKATEQEVRDFAQRMLLSRPAIAGFGK 491
G + + + +I+ ++ A+ + AG GK
Sbjct: 399 HGRKIPVNEMISKIEDLKPDDISRVAEMIFTGNVNNAGNGK 439
>sp|Q9ZU25|MPPA1_ARATH Probable mitochondrial processing peptidase alpha subunit 1,
mitochondrial precursor (Alpha-MPP 1)
Length = 503
Score = 92.8 bits (229), Expect = 7e-19
Identities = 56/174 (32%), Positives = 90/174 (51%), Gaps = 1/174 (0%)
Frame = +3
Query: 6 VHACLLQTLMXXXXXXXXXXXXXXMFSRLYKEVLHKYPWVNSVVAMNHSYSDTGLFTITG 185
V A +LQ LM M S LY+ VL++Y V S A ++DTGLF I G
Sbjct: 326 VTATVLQMLMGGGGSFSAGGPGKGMHSWLYRRVLNEYQEVQSCTAFTSIFNDTGLFGIYG 385
Query: 186 SSVPGNLDTLALVLAHQLKNMVKS-IDKEDFARAKCQLKSMLLMNLETRAVVFEDIGRQV 362
S P + A +LK++ +++ RAK KS +LMNLE+R + EDIGRQ+
Sbjct: 386 CSSPQFAAKAIELAAKELKDVAGGKVNQAHLDRAKAATKSAVLMNLESRMIAAEDIGRQI 445
Query: 363 IYQGHRNSADYWVEQIDKATEQEVRDFAQRMLLSRPAIAGFGKLEKLQSLEVIT 524
+ G R D +++ +D+ T +++ DF +++ + FG + + S + I+
Sbjct: 446 LTYGERKPVDQFLKSVDQLTLKDIADFTSKVISKPLTMGSFGDVLAVPSYDTIS 499
>sp|P29677|MPPA_SOLTU Mitochondrial processing peptidase alpha subunit, mitochondrial
precursor (Alpha-MPP) (Ubiquinol-cytochrome-c reductase
subunit II)
Length = 504
Score = 89.7 bits (221), Expect = 6e-18
Identities = 53/171 (30%), Positives = 91/171 (53%), Gaps = 2/171 (1%)
Frame = +3
Query: 18 LLQTLMXXXXXXXXXXXXXXMFSRLYKEVLHKYPWVNSVVAMNHSYSDTGLFTITGSSVP 197
+LQ LM M+SRLY VL++YP +++ A + Y++TGLF I G++
Sbjct: 328 VLQMLMGGGGSFSAGGPGKGMYSRLYLRVLNQYPQIHAFSAFSSIYNNTGLFGIQGTTSS 387
Query: 198 GNLDTLALVLAHQLKNMVK--SIDKEDFARAKCQLKSMLLMNLETRAVVFEDIGRQVIYQ 371
V +L + +D+ RAK KS +LMNLE+R V EDIGRQ++
Sbjct: 388 DFGPQAVDVAVKELIAVANPSEVDQVQLNRAKQATKSAILMNLESRMVASEDIGRQLLTY 447
Query: 372 GHRNSADYWVEQIDKATEQEVRDFAQRMLLSRPAIAGFGKLEKLQSLEVIT 524
G RN +++++ ID + +++ Q+++ S +A +G + L S + ++
Sbjct: 448 GERNPVEHFLKAIDAVSAKDIASVVQKLISSPLTMASYGDVLSLPSYDAVS 498
>sp|O04308|MPPA2_ARATH Probable mitochondrial processing peptidase alpha subunit 2,
mitochondrial precursor (Alpha-MPP 2)
Length = 499
Score = 82.8 bits (203), Expect = 7e-16
Identities = 49/173 (28%), Positives = 89/173 (51%), Gaps = 1/173 (0%)
Frame = +3
Query: 12 ACLLQTLMXXXXXXXXXXXXXXMFSRLYKEVLHKYPWVNSVVAMNHSYSDTGLFTITGSS 191
A +LQ LM M S LY +L+++ S A +++TGLF I G +
Sbjct: 324 ATVLQMLMGGGGSFSAGGPGKGMHSWLYLRLLNQHQQFQSCTAFTSVFNNTGLFGIYGCT 383
Query: 192 VPGNLDTLALVLAHQLKNMVKS-IDKEDFARAKCQLKSMLLMNLETRAVVFEDIGRQVIY 368
P ++A ++ + ++++ RAK KS +LMNLE+R + EDIGRQ++
Sbjct: 384 SPEFASQGIELVASEMNAVADGKVNQKHLDRAKAATKSAILMNLESRMIAAEDIGRQILT 443
Query: 369 QGHRNSADYWVEQIDKATEQEVRDFAQRMLLSRPAIAGFGKLEKLQSLEVITK 527
G R D +++ +D+ T +++ DF +++ +A FG + + S + ++K
Sbjct: 444 YGERKPVDQFLKTVDQLTLKDIADFTSKVITKPLTMATFGDVLNVPSYDSVSK 496
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 66,786,570
Number of Sequences: 369166
Number of extensions: 1228548
Number of successful extensions: 3176
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3098
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3161
length of database: 68,354,980
effective HSP length: 106
effective length of database: 48,773,070
effective search space used: 5560129980
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)