Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_007_M05
(875 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q8VH51|RNPC2_MOUSE RNA-binding region containing protein... 209 6e-54
sp|Q14498|RNPC2_HUMAN RNA-binding region containing protein... 209 1e-53
sp|Q86U06|RBM23_HUMAN Probable RNA-binding protein 23 (RNA-... 150 6e-36
sp|P04147|PABP_YEAST Polyadenylate-binding protein, cytopla... 73 9e-13
sp|P15771|NUCL_CHICK Nucleolin (Protein C23) 72 3e-12
sp|Q13310|PABP4_HUMAN Polyadenylate-binding protein 4 (Poly... 70 6e-12
sp|O64380|PABP3_ARATH Polyadenylate-binding protein 3 (Poly... 67 6e-11
sp|P19338|NUCL_HUMAN Nucleolin (Protein C23) 67 8e-11
sp|Q05196|PABP5_ARATH Polyadenylate-binding protein 5 (Poly... 66 1e-10
sp|P29341|PABP1_MOUSE Polyadenylate-binding protein 1 (Poly... 65 3e-10
>sp|Q8VH51|RNPC2_MOUSE RNA-binding region containing protein 2 (Coactivator of activating
protein 1 and estrogen receptors) (Coactivator of AP-1
and ERs) (Transcription coactivator CAPER)
Length = 530
Score = 209 bits (533), Expect = 6e-54
Identities = 135/336 (40%), Positives = 180/336 (53%), Gaps = 47/336 (13%)
Frame = +3
Query: 9 LTDEEKDARTVNVWQLSHRVRTRDLEDLFSTVGKLCVVRLILDPRSGKSRGVAYIQFRNT 188
LT EE+DARTV QL+ R+R RDLE+ FSTVGK+ VR+I D S +SRG+AY++F +
Sbjct: 145 LTPEERDARTVFCMQLAARIRPRDLEEFFSTVGKVRDVRMISDRNSRRSRGIAYVEFVDV 204
Query: 189 ESVDKAXXXXXXXXXXVPIMIRTVSSEKCRAAEASMGGGGINMKGPTKLCISNLHEIITE 368
SV A VPI+++ +EK RAA A GP +L + +LH ITE
Sbjct: 205 SSVRLAIGLTGQRVLGVPIIVQASQAEKNRAA-AMANNLQKGSAGPMRLYVGSLHFNITE 263
Query: 369 KHLEEIFSPYGTINEIKLLNDI-NGRSSGTAFITFQKGENAKMALDQLNEFVLAQKPMKI 545
L IF P+G I I+L+ D GRS G FITF E AK AL+QLN F LA +PMK+
Sbjct: 264 DMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDSECAKKALEQLNGFELAGRPMKV 323
Query: 546 TPVTE--------SNFGSELNESQGVSMSASDRLGLMAKLAVGTSLQITPTV-------- 677
VTE S S+ E G+ + + RL LMA+LA GT LQI P
Sbjct: 324 GHVTERTDASSASSFLDSDELERTGIDLGTTGRLQLMARLAEGTGLQIPPAAQQALQMSG 383
Query: 678 ----------------------RTDERVV--------ISTQCIVLSNMFDVADAQDEEFC 767
+T+ + ++TQC LSNMF+ ++ +
Sbjct: 384 SLAFGAVAEFSFVIDLQTRLSQQTEASALAAAASVQPLATQCFQLSNMFNPQTEEEVGWD 443
Query: 768 EEITEDIIAECSKLGGVLHVHVDKKGPSGNVYIKCP 875
EI +D+I EC+K GGV+H++VDK GNVY+KCP
Sbjct: 444 TEIKDDVIEECNKHGGVIHIYVDKNSAQGNVYVKCP 479
>sp|Q14498|RNPC2_HUMAN RNA-binding region containing protein 2 (Hepatocellular carcinoma
protein 1) (Splicing factor HCC1)
Length = 530
Score = 209 bits (531), Expect = 1e-53
Identities = 134/336 (39%), Positives = 180/336 (53%), Gaps = 47/336 (13%)
Frame = +3
Query: 9 LTDEEKDARTVNVWQLSHRVRTRDLEDLFSTVGKLCVVRLILDPRSGKSRGVAYIQFRNT 188
LT EE+DARTV QL+ R+R RDLE+ FSTVGK+ VR+I D S +S+G+AY++F +
Sbjct: 145 LTPEERDARTVFCMQLAARIRPRDLEEFFSTVGKVRDVRMISDRNSRRSKGIAYVEFVDV 204
Query: 189 ESVDKAXXXXXXXXXXVPIMIRTVSSEKCRAAEASMGGGGINMKGPTKLCISNLHEIITE 368
SV A VPI+++ +EK RAA A GP +L + +LH ITE
Sbjct: 205 SSVPLAIGLTGQRVLGVPIIVQASQAEKNRAA-AMANNLQKGSAGPMRLYVGSLHFNITE 263
Query: 369 KHLEEIFSPYGTINEIKLLNDI-NGRSSGTAFITFQKGENAKMALDQLNEFVLAQKPMKI 545
L IF P+G I I+L+ D GRS G FITF E AK AL+QLN F LA +PMK+
Sbjct: 264 DMLRGIFEPFGRIESIQLMMDSETGRSKGYGFITFSDSECAKKALEQLNGFELAGRPMKV 323
Query: 546 TPVTE--------SNFGSELNESQGVSMSASDRLGLMAKLAVGTSLQITPTV-------- 677
VTE S S+ E G+ + + RL LMA+LA GT LQI P
Sbjct: 324 GHVTERTDASSASSFLDSDELERTGIDLGTTGRLQLMARLAEGTGLQIPPAAQQALQMSG 383
Query: 678 ----------------------RTDERVV--------ISTQCIVLSNMFDVADAQDEEFC 767
+T+ + ++TQC LSNMF+ ++ +
Sbjct: 384 SLAFGAVAEFSFVIDLQTRLSQQTEASALAAAASVQPLATQCFQLSNMFNPQTEEEVGWD 443
Query: 768 EEITEDIIAECSKLGGVLHVHVDKKGPSGNVYIKCP 875
EI +D+I EC+K GGV+H++VDK GNVY+KCP
Sbjct: 444 TEIKDDVIEECNKHGGVIHIYVDKNSAQGNVYVKCP 479
>sp|Q86U06|RBM23_HUMAN Probable RNA-binding protein 23 (RNA-binding motif protein 23)
(RNA-binding region containing protein 4) (Splicing
factor SF2)
Length = 439
Score = 150 bits (378), Expect = 6e-36
Identities = 98/231 (42%), Positives = 133/231 (57%), Gaps = 9/231 (3%)
Frame = +3
Query: 9 LTDEEKDARTVNVWQLSHRVRTRDLEDLFSTVGKLCVVRLILDPRSGKSRGVAYIQFRNT 188
L+ EE+DARTV QL+ R+R RDLED FS VGK+ VR+I D S +S+G+AY++F
Sbjct: 158 LSPEERDARTVFCMQLAARIRPRDLEDFFSAVGKVRDVRIISDRNSRRSKGIAYVEFCEI 217
Query: 189 ESVDKAXXXXXXXXXXVPIMIRTVSSEKCRAAEAS---MGGGGINMKGPTKLCISNLHEI 359
+SV A VPI+++ +EK R A + G G GP +L + +LH
Sbjct: 218 QSVPLAIGLTGQRLLGVPIIVQASQAEKNRLAAMANNLQKGNG----GPMRLYVGSLHFN 273
Query: 360 ITEKHLEEIFSPYGTINEIKLLNDIN-GRSSGTAFITFQKGENAKMALDQLNEFVLAQKP 536
ITE L IF P+G I+ I L+ D + GRS G FITF E A+ AL+QLN F LA +P
Sbjct: 274 ITEDMLRGIFEPFGKIDNIVLMKDSDTGRSKGYGFITFSDSECARRALEQLNGFELAGRP 333
Query: 537 MKITPVTES-NFGSELNESQGVSM----SASDRLGLMAKLAVGTSLQITPT 674
M++ VTE + G+++ G SA R LMAKLA G +Q+ T
Sbjct: 334 MRVGHVTERLDGGTDITFPDGDQELDLGSAGGRFQLMAKLAEGAGIQLPST 384
>sp|P04147|PABP_YEAST Polyadenylate-binding protein, cytoplasmic and nuclear
(Poly(A)-binding protein) (PABP) (ARS consensus binding
protein ACBP-67) (Polyadenylate tail-binding protein)
Length = 577
Score = 73.2 bits (178), Expect = 9e-13
Identities = 54/192 (28%), Positives = 87/192 (45%), Gaps = 1/192 (0%)
Frame = +3
Query: 21 EKDARTVNVWQLSHRVRTRDLEDLFSTVGKLCVVRLILDPRSGKSRGVAYIQFRNTESVD 200
E + ++ V L V L D+FS +G + +R+ D + S G AY+ F + E+
Sbjct: 34 ENSSASLYVGDLEPSVSEAHLYDIFSPIGSVSSIRVCRDAITKTSLGYAYVNFNDHEAGR 93
Query: 201 KAXXXXXXXXXXVPIMIRTVSSEKCRAAEASMGGGGINMKGPTKLCISNLHEIITEKHLE 380
KA + + CR S + KG + I NLH I K L
Sbjct: 94 KAIEQ---------LNYTPIKGRLCRIMW-SQRDPSLRKKGSGNIFIKNLHPDIDNKALY 143
Query: 381 EIFSPYGTINEIKLLNDINGRSSGTAFITFQKGENAKMALDQLNEFVLAQKPMKITP-VT 557
+ FS +G I K+ D NG+S G F+ F++ AK A+D LN +L + + + P ++
Sbjct: 144 DTFSVFGDILSSKIATDENGKSKGFGFVHFEEEGAAKEAIDALNGMLLNGQEIYVAPHLS 203
Query: 558 ESNFGSELNESQ 593
S+L E++
Sbjct: 204 RKERDSQLEETK 215
Score = 58.5 bits (140), Expect = 2e-08
Identities = 45/184 (24%), Positives = 78/184 (42%), Gaps = 8/184 (4%)
Frame = +3
Query: 18 EEKDARTVNVWQLSHRVRTRD--LEDLFSTVGKLCVVRLILDPRSGKSRGVAYIQFRNTE 191
EE A N++ + T D ++LF+ G + L D GK +G ++ + E
Sbjct: 212 EETKAHYTNLYVKNINSETTDEQFQELFAKFGPIVSASLEKDA-DGKLKGFGFVNYEKHE 270
Query: 192 SVDKAXXXXXXXXXX-VPIMIRTVSSEKCRAAEASMGGGGINMKGPTK-----LCISNLH 353
KA + + + R ++ K L + NL
Sbjct: 271 DAVKAVEALNDSELNGEKLYVGRAQKKNERMHVLKKQYEAYRLEKMAKYQGVNLFVKNLD 330
Query: 354 EIITEKHLEEIFSPYGTINEIKLLNDINGRSSGTAFITFQKGENAKMALDQLNEFVLAQK 533
+ + ++ LEE F+PYGTI K++ NG+S G F+ F E A A+ + N+ ++A K
Sbjct: 331 DSVDDEKLEEEFAPYGTITSAKVMRTENGKSKGFGFVCFSTPEEATKAITEKNQQIVAGK 390
Query: 534 PMKI 545
P+ +
Sbjct: 391 PLYV 394
>sp|P15771|NUCL_CHICK Nucleolin (Protein C23)
Length = 694
Score = 71.6 bits (174), Expect = 3e-12
Identities = 53/180 (29%), Positives = 91/180 (50%)
Frame = +3
Query: 6 KLTDEEKDARTVNVWQLSHRVRTRDLEDLFSTVGKLCVVRLILDPRSGKSRGVAYIQFRN 185
K +E+DART+ V L +RV +++++F + VRL+L+ + G S+G+AYI+F+
Sbjct: 362 KENKKERDARTLFVKNLPYRVTEDEMKNVFENALE---VRLVLN-KEGSSKGMAYIEFKT 417
Query: 186 TESVDKAXXXXXXXXXXVPIMIRTVSSEKCRAAEASMGGGGINMKGPTKLCISNLHEIIT 365
+KA M+ + EK + E+ GGG K L ++NL +
Sbjct: 418 EAEAEKALEEKQGTEVDGRAMVIDYTGEKSQ-QESQKGGGERESK---TLIVNNLSYAAS 473
Query: 366 EKHLEEIFSPYGTINEIKLLNDINGRSSGTAFITFQKGENAKMALDQLNEFVLAQKPMKI 545
E+ L+E+F IK+ + GR G AF+ F E+AK AL+ N + + +++
Sbjct: 474 EETLQELFK---KATSIKMPQNNQGRPKGYAFVEFPTAEDAKEALNSCNNTEIEGRAIRL 530
>sp|Q13310|PABP4_HUMAN Polyadenylate-binding protein 4 (Poly(A)-binding protein 4) (PABP
4) (Inducible poly(A)-binding protein) (iPABP)
(Activated-platelet protein 1) (APP-1)
Length = 644
Score = 70.5 bits (171), Expect = 6e-12
Identities = 44/159 (27%), Positives = 77/159 (48%), Gaps = 1/159 (0%)
Frame = +3
Query: 39 VNVWQLSHRVRTRDLEDLFSTVGKLCVVRLILDPRSGKSRGVAYIQFRNTESVDKAXXXX 218
V + L + + L D FS G + +++ D S+G A++ F E+ DKA
Sbjct: 101 VFIKNLDKSIDNKALYDTFSAFGNILSCKVVCDENG--SKGYAFVHFETQEAADKAIEKM 158
Query: 219 XXXXXXV-PIMIRTVSSEKCRAAEASMGGGGINMKGPTKLCISNLHEIITEKHLEEIFSP 395
+ + S K R AE G K T + I N E + ++ L+E+FS
Sbjct: 159 NGMLLNDRKVFVGRFKSRKEREAEL-----GAKAKEFTNVYIKNFGEEVDDESLKELFSQ 213
Query: 396 YGTINEIKLLNDINGRSSGTAFITFQKGENAKMALDQLN 512
+G +K++ D NG+S G F++++K E+A A++++N
Sbjct: 214 FGKTLSVKVMRDPNGKSKGFGFVSYEKHEDANKAVEEMN 252
Score = 68.6 bits (166), Expect = 2e-11
Identities = 50/186 (26%), Positives = 88/186 (47%), Gaps = 6/186 (3%)
Frame = +3
Query: 6 KLTDEEKDARTVNVWQLSHRVRTRDLEDLFSTVGKLCVVRLILDPRSGKSRGVAYIQFRN 185
+L + K+ V + V L++LFS GK V+++ DP +GKS+G ++ +
Sbjct: 182 ELGAKAKEFTNVYIKNFGEEVDDESLKELFSQFGKTLSVKVMRDP-NGKSKGFGFVSYEK 240
Query: 186 TESVDKAXXXXXXXXXXVPIMIRTVSSEKC-RAAEAS-----MGGGGINMKGPTKLCISN 347
E +KA I+ + +K R AE + I+ L I N
Sbjct: 241 HEDANKAVEEMNGKEISGKIIFVGRAQKKVERQAELKRKFEQLKQERISRYQGVNLYIKN 300
Query: 348 LHEIITEKHLEEIFSPYGTINEIKLLNDINGRSSGTAFITFQKGENAKMALDQLNEFVLA 527
L + I ++ L + FSP+G+I K++ + +GRS G F+ F E A A+ ++N ++
Sbjct: 301 LDDTIDDEKLRKEFSPFGSITSAKVMLE-DGRSKGFGFVCFSSPEEATKAVTEMNGRIVG 359
Query: 528 QKPMKI 545
KP+ +
Sbjct: 360 SKPLYV 365
Score = 52.0 bits (123), Expect = 2e-06
Identities = 29/72 (40%), Positives = 44/72 (61%), Gaps = 1/72 (1%)
Frame = +3
Query: 333 LCISNLHEIITEKHLEEIFSPYGTINEIKLLND-INGRSSGTAFITFQKGENAKMALDQL 509
L + +LH +TE L E FSP G + I++ D I RS G A++ FQ+ +A+ ALD +
Sbjct: 13 LYVGDLHSDVTEAMLYEKFSPAGPVLSIRVCRDMITRRSLGYAYVNFQQPADAERALDTM 72
Query: 510 NEFVLAQKPMKI 545
N V+ KP++I
Sbjct: 73 NFDVIKGKPIRI 84
>sp|O64380|PABP3_ARATH Polyadenylate-binding protein 3 (Poly(A)-binding protein 3) (PABP
3)
Length = 660
Score = 67.0 bits (162), Expect = 6e-11
Identities = 51/175 (29%), Positives = 77/175 (44%)
Frame = +3
Query: 9 LTDEEKDARTVNVWQLSHRVRTRDLEDLFSTVGKLCVVRLILDPRSGKSRGVAYIQFRNT 188
+ D+ ++ L +V L DLF V + VR+ D ++ +S G AYI F N
Sbjct: 41 VADQTHPNSSLYAGDLDPKVTEAHLFDLFKHVANVVSVRVCRD-QNRRSLGYAYINFSNP 99
Query: 189 ESVDKAXXXXXXXXXXVPIMIRTVSSEKCRAAEASMGGGGINMKGPTKLCISNLHEIITE 368
+A P+ R + S + G + I NL I
Sbjct: 100 NDAYRAMEALNY----TPLFDRPIR------IMLSNRDPSTRLSGKGNIFIKNLDASIDN 149
Query: 369 KHLEEIFSPYGTINEIKLLNDINGRSSGTAFITFQKGENAKMALDQLNEFVLAQK 533
K L E FS +GTI K+ D+ GRS G F+ F+K E+A+ A+D+LN ++ K
Sbjct: 150 KALFETFSSFGTILSCKVAMDVTGRSKGYGFVQFEKEESAQAAIDKLNGMLMNDK 204
Score = 54.7 bits (130), Expect = 3e-07
Identities = 40/171 (23%), Positives = 72/171 (42%), Gaps = 17/171 (9%)
Frame = +3
Query: 84 EDLFSTVGKLCVVR--LILDPRSGKSRGVAYIQFRNTESVDKAXXXXXXXXXXVPIMI-- 251
++L T GK V+ +++ +SG SR ++ F TE+ A ++
Sbjct: 243 DELRKTFGKFGVISSAVVMRDQSGNSRCFGFVNFECTEAAASAVEKMNGISLGDDVLYVG 302
Query: 252 -------------RTVSSEKCRAAEASMGGGGINMKGPTKLCISNLHEIITEKHLEEIFS 392
R E+ E S G L + NL + + ++ L+E+FS
Sbjct: 303 RAQKKSEREEELRRKFEQERINRFEKSQGAN---------LYLKNLDDSVDDEKLKEMFS 353
Query: 393 PYGTINEIKLLNDINGRSSGTAFITFQKGENAKMALDQLNEFVLAQKPMKI 545
YG + K++ + G S G F+ + E A AL ++N ++ +KP+ I
Sbjct: 354 EYGNVTSSKVMLNPQGMSRGFGFVAYSNPEEALRALSEMNGKMIGRKPLYI 404
>sp|P19338|NUCL_HUMAN Nucleolin (Protein C23)
Length = 707
Score = 66.6 bits (161), Expect = 8e-11
Identities = 51/171 (29%), Positives = 85/171 (49%), Gaps = 1/171 (0%)
Frame = +3
Query: 6 KLTDEEKDARTVNVWQLSHRVRTRDLEDLFSTVGKLCVVRLILDPRSGKSRGVAYIQFRN 185
K + +E+DART+ L ++V +L+++F ++ +V + GKS+G+AYI+F+
Sbjct: 384 KDSKKERDARTLLAKNLPYKVTQDELKEVFEDAAEIRLVS-----KDGKSKGIAYIEFKT 438
Query: 186 TESVDKAXXXXXXXXXXVPIMIRTVSSEKCRAAEASMGGGGINMKGPTK-LCISNLHEII 362
+K + + EK + + GG G +K L +SNL
Sbjct: 439 EADAEKTFEEKQGTEIDGRSISLYYTGEKGQNQDYR-GGKNSTWSGESKTLVLSNLSYSA 497
Query: 363 TEKHLEEIFSPYGTINEIKLLNDINGRSSGTAFITFQKGENAKMALDQLNE 515
TE+ L+E+F IK+ + NG+S G AFI F E+AK AL+ N+
Sbjct: 498 TEETLQEVFEK---ATFIKVPQNQNGKSKGYAFIEFASFEDAKEALNSCNK 545
>sp|Q05196|PABP5_ARATH Polyadenylate-binding protein 5 (Poly(A)-binding protein 5) (PABP
5)
Length = 668
Score = 65.9 bits (159), Expect = 1e-10
Identities = 52/163 (31%), Positives = 72/163 (44%)
Frame = +3
Query: 45 VWQLSHRVRTRDLEDLFSTVGKLCVVRLILDPRSGKSRGVAYIQFRNTESVDKAXXXXXX 224
V L V L DLF+ V + +R+ D + +S G AY+ F N E +A
Sbjct: 49 VGDLDPSVNESHLLDLFNQVAPVHNLRVCRD-LTHRSLGYAYVNFANPEDASRAMESLNY 107
Query: 225 XXXXVPIMIRTVSSEKCRAAEASMGGGGINMKGPTKLCISNLHEIITEKHLEEIFSPYGT 404
PI R + S + G + I NL I K L E FS +GT
Sbjct: 108 ----APIRDRPIR------IMLSNRDPSTRLSGKGNVFIKNLDASIDNKALYETFSSFGT 157
Query: 405 INEIKLLNDINGRSSGTAFITFQKGENAKMALDQLNEFVLAQK 533
I K+ D+ GRS G F+ F+K E A+ A+D+LN +L K
Sbjct: 158 ILSCKVAMDVVGRSKGYGFVQFEKEETAQAAIDKLNGMLLNDK 200
Score = 51.6 bits (122), Expect = 3e-06
Identities = 37/176 (21%), Positives = 78/176 (44%), Gaps = 7/176 (3%)
Frame = +3
Query: 39 VNVWQLSHRVRTRDLEDLFSTVGKLCVVRLILDPRSGKSRGVAYIQFRNTESVDKAXXXX 218
V V L + +L+ F G + +++ +SG SR ++ F + E+ A
Sbjct: 227 VYVKNLPKEITDDELKKTFGKYGDISSA-VVMKDQSGNSRSFGFVNFVSPEAAAVAVEKM 285
Query: 219 XXXXXXVPIMIRTVSSEKC-------RAAEASMGGGGINMKGPTKLCISNLHEIITEKHL 377
++ + +K R E ++G + L + NL + + ++ L
Sbjct: 286 NGISLGEDVLYVGRAQKKSDREEELRRKFEQERISRFEKLQG-SNLYLKNLDDSVNDEKL 344
Query: 378 EEIFSPYGTINEIKLLNDINGRSSGTAFITFQKGENAKMALDQLNEFVLAQKPMKI 545
+E+FS YG + K++ + G S G F+ + E A +A+ ++N ++ +KP+ +
Sbjct: 345 KEMFSEYGNVTSCKVMMNSQGLSRGFGFVAYSNPEEALLAMKEMNGKMIGRKPLYV 400
>sp|P29341|PABP1_MOUSE Polyadenylate-binding protein 1 (Poly(A)-binding protein 1) (PABP
1)
Length = 636
Score = 64.7 bits (156), Expect = 3e-10
Identities = 39/154 (25%), Positives = 75/154 (48%), Gaps = 1/154 (0%)
Frame = +3
Query: 54 LSHRVRTRDLEDLFSTVGKLCVVRLILDPRSGKSRGVAYIQFRNTESVDKAXXXXXXXXX 233
L + + L D FS G + +++ D S+G ++ F E+ ++A
Sbjct: 106 LDKSIDNKALYDTFSAFGNILSCKVVCDENG--SKGYGFVHFETQEAAERAIEKMNGMLL 163
Query: 234 XV-PIMIRTVSSEKCRAAEASMGGGGINMKGPTKLCISNLHEIITEKHLEEIFSPYGTIN 410
+ + S+K R AE G K T + I N E + ++ L+E+F +G
Sbjct: 164 NDRKVFVGRFKSQKEREAEL-----GARAKEFTNVYIKNFGEDMDDERLKELFGKFGPAL 218
Query: 411 EIKLLNDINGRSSGTAFITFQKGENAKMALDQLN 512
+K++ D +G+S G F++F++ E+A+ A+D++N
Sbjct: 219 SVKVMTDESGKSKGFGFVSFERHEDAQKAVDEMN 252
Score = 60.8 bits (146), Expect = 5e-09
Identities = 45/161 (27%), Positives = 72/161 (44%), Gaps = 6/161 (3%)
Frame = +3
Query: 81 LEDLFSTVGKLCVVRLILDPRSGKSRGVAYIQFRNTESVDKAXXXXXXXXXX-VPIMIRT 257
L++LF G V+++ D SGKS+G ++ F E KA I +
Sbjct: 207 LKELFGKFGPALSVKVMTD-ESGKSKGFGFVSFERHEDAQKAVDEMNGKELNGKQIYVGR 265
Query: 258 VSSEKCRAAEAS-----MGGGGINMKGPTKLCISNLHEIITEKHLEEIFSPYGTINEIKL 422
+ R E M I L + NL + I ++ L + FSP+GTI K+
Sbjct: 266 AQKKVERQTELKRKFEQMKQDRITRYQGVNLYVKNLDDGIDDERLRKEFSPFGTITSAKV 325
Query: 423 LNDINGRSSGTAFITFQKGENAKMALDQLNEFVLAQKPMKI 545
+ + GRS G F+ F E A A+ ++N ++A KP+ +
Sbjct: 326 MME-GGRSKGFGFVCFSSPEEATKAVTEMNGRIVATKPLYV 365
Score = 52.0 bits (123), Expect = 2e-06
Identities = 30/72 (41%), Positives = 44/72 (61%), Gaps = 1/72 (1%)
Frame = +3
Query: 333 LCISNLHEIITEKHLEEIFSPYGTINEIKLLND-INGRSSGTAFITFQKGENAKMALDQL 509
L + +LH +TE L E FSP G I I++ D I RS G A++ FQ+ +A+ ALD +
Sbjct: 13 LYVGDLHPDVTEAMLYEKFSPAGPILSIRVCRDMITRRSLGYAYVNFQQPADAERALDTM 72
Query: 510 NEFVLAQKPMKI 545
N V+ KP++I
Sbjct: 73 NFDVIKGKPVRI 84
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 99,108,456
Number of Sequences: 369166
Number of extensions: 1949278
Number of successful extensions: 5507
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5079
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5407
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 8694177530
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)