Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_007_J18
(792 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P51121|GLNA_XENLA Glutamine synthetase (Glutamate--ammon... 355 1e-97
sp|Q8HZM5|GLNA_CANFA Glutamine synthetase (Glutamate--ammon... 349 6e-96
sp|Q9QY94|GLNA_ACOCA Glutamine synthetase (Glutamate--ammon... 348 1e-95
sp|P15104|GLNA_HUMAN Glutamine synthetase (Glutamate--ammon... 346 4e-95
sp|P20478|GLNA2_DROME Glutamine synthetase 2, cytoplasmic (... 346 4e-95
sp|Q4R7U3|GLNA_MACFA Glutamine synthetase (Glutamate--ammon... 346 4e-95
sp|P46410|GLNA_PIG Glutamine synthetase (Glutamate--ammonia... 345 1e-94
sp|P15105|GLNA_MOUSE Glutamine synthetase (Glutamate--ammon... 344 2e-94
sp|P16580|GLNA_CHICK Glutamine synthetase (Glutamate--ammon... 343 3e-94
sp|Q04831|GLNA_PANAR Glutamine synthetase (Glutamate--ammon... 341 2e-93
>sp|P51121|GLNA_XENLA Glutamine synthetase (Glutamate--ammonia ligase)
Length = 392
Score = 355 bits (910), Expect = 1e-97
Identities = 155/215 (72%), Positives = 188/215 (87%)
Frame = +2
Query: 50 WPKLGFPGAQGPYYCGVGCNKVFGRDIIEAHYKACLFAGIKIAGTNAEVMPAQWEFQIGP 229
WP+ GFPG QGPYYCGVG +KV+GRD++E+HYKACL+AGIKI GTNAEVMP+QWEFQ+GP
Sbjct: 149 WPENGFPGPQGPYYCGVGADKVYGRDVVESHYKACLYAGIKICGTNAEVMPSQWEFQVGP 208
Query: 230 CEGINVSDHLWMARYLLHRVAEDFGVVVSFDPKPIAGDWNGAGAHTNYSTIQMRSPGGIK 409
CEGI++ DHLWMAR++LHRV EDFGVV + DPKP+ G+WNGAG HTNYST MR GG+K
Sbjct: 209 CEGIDMGDHLWMARFILHRVCEDFGVVATLDPKPMTGNWNGAGCHTNYSTESMRVEGGLK 268
Query: 410 YIEEAIEKMSKRHHEHIEAYDPHKGEDNRRRLTGRHETSTIDDFSSGVANRGASIRIPRQ 589
+IE+AIEK+ KRH HI YDP G+DN RRLTG+HETS+I +FS+GVANRGASIRIPRQ
Sbjct: 269 HIEDAIEKLGKRHDYHICVYDPRGGKDNSRRLTGQHETSSIHEFSAGVANRGASIRIPRQ 328
Query: 590 VSEDGFGYLEDRRPSSNCDPYSVTERIVRTTILED 694
V ++G+GY EDRRP++NCDPY+VTE +VRTTIL +
Sbjct: 329 VGQEGYGYFEDRRPAANCDPYAVTEALVRTTILNE 363
>sp|Q8HZM5|GLNA_CANFA Glutamine synthetase (Glutamate--ammonia ligase) (GS)
Length = 373
Score = 349 bits (895), Expect = 6e-96
Identities = 156/215 (72%), Positives = 183/215 (85%)
Frame = +2
Query: 50 WPKLGFPGAQGPYYCGVGCNKVFGRDIIEAHYKACLFAGIKIAGTNAEVMPAQWEFQIGP 229
WP GFPG QGPYYCGVG +K +GRDI+EAHY+ACL+AGIKIAGTNAEVMPAQWEFQIGP
Sbjct: 149 WPSNGFPGPQGPYYCGVGADKAYGRDIVEAHYRACLYAGIKIAGTNAEVMPAQWEFQIGP 208
Query: 230 CEGINVSDHLWMARYLLHRVAEDFGVVVSFDPKPIAGDWNGAGAHTNYSTIQMRSPGGIK 409
CEGI++ DHLW+AR++LHRV EDFGV+ +FDPKPI G+WNGAG HTN+ST MR G+K
Sbjct: 209 CEGIDMGDHLWVARFILHRVCEDFGVIATFDPKPIPGNWNGAGCHTNFSTKAMREENGLK 268
Query: 410 YIEEAIEKMSKRHHEHIEAYDPHKGEDNRRRLTGRHETSTIDDFSSGVANRGASIRIPRQ 589
YIEE+IEK+SKRH HI AYDP G DN RRLTG HETS I+DFS+GVANRGASIRIPR
Sbjct: 269 YIEESIEKLSKRHQYHIRAYDPKGGLDNARRLTGFHETSNINDFSAGVANRGASIRIPRT 328
Query: 590 VSEDGFGYLEDRRPSSNCDPYSVTERIVRTTILED 694
V ++ GY EDRRPS+NCDP+SVTE ++RT +L +
Sbjct: 329 VGQEKKGYFEDRRPSANCDPFSVTEALIRTCLLNE 363
>sp|Q9QY94|GLNA_ACOCA Glutamine synthetase (Glutamate--ammonia ligase) (GS)
Length = 373
Score = 348 bits (893), Expect = 1e-95
Identities = 156/215 (72%), Positives = 181/215 (84%)
Frame = +2
Query: 50 WPKLGFPGAQGPYYCGVGCNKVFGRDIIEAHYKACLFAGIKIAGTNAEVMPAQWEFQIGP 229
WP GFPG QGPYYCGVG +K +GRDI+EAHY+ACL+AG+KI GTNAEVMPAQWEFQIGP
Sbjct: 149 WPSNGFPGPQGPYYCGVGADKAYGRDIVEAHYRACLYAGVKITGTNAEVMPAQWEFQIGP 208
Query: 230 CEGINVSDHLWMARYLLHRVAEDFGVVVSFDPKPIAGDWNGAGAHTNYSTIQMRSPGGIK 409
CEGI + DHLW+AR++LHRV EDFGV+ +FDPKPI G+WNGAG HTN+ST MR G+K
Sbjct: 209 CEGIRMGDHLWVARFILHRVCEDFGVIATFDPKPIPGNWNGAGCHTNFSTKAMREENGLK 268
Query: 410 YIEEAIEKMSKRHHEHIEAYDPHKGEDNRRRLTGRHETSTIDDFSSGVANRGASIRIPRQ 589
YIEEAI+K+SKRH HI AYDP G DN RRLTG HETS I+DFS+GVANRGASIRIPR
Sbjct: 269 YIEEAIDKLSKRHQYHIRAYDPKGGLDNARRLTGFHETSNINDFSAGVANRGASIRIPRT 328
Query: 590 VSEDGFGYLEDRRPSSNCDPYSVTERIVRTTILED 694
V ++ GY EDRRPS+NCDPY+VTE IVRT +L +
Sbjct: 329 VGQEKRGYFEDRRPSANCDPYAVTEAIVRTCLLNE 363
>sp|P15104|GLNA_HUMAN Glutamine synthetase (Glutamate--ammonia ligase) (GS)
Length = 373
Score = 346 bits (888), Expect = 4e-95
Identities = 154/215 (71%), Positives = 182/215 (84%)
Frame = +2
Query: 50 WPKLGFPGAQGPYYCGVGCNKVFGRDIIEAHYKACLFAGIKIAGTNAEVMPAQWEFQIGP 229
WP GFPG QGPYYCGVG ++ +GRDI+EAHY+ACL+AG+KIAGTNAEVMPAQWEFQIGP
Sbjct: 149 WPSNGFPGPQGPYYCGVGADRAYGRDIVEAHYRACLYAGVKIAGTNAEVMPAQWEFQIGP 208
Query: 230 CEGINVSDHLWMARYLLHRVAEDFGVVVSFDPKPIAGDWNGAGAHTNYSTIQMRSPGGIK 409
CEGI++ DHLW+AR++LHRV EDFGV+ +FDPKPI G+WNGAG HTN+ST MR G+K
Sbjct: 209 CEGISMGDHLWVARFILHRVCEDFGVIATFDPKPIPGNWNGAGCHTNFSTKAMREENGLK 268
Query: 410 YIEEAIEKMSKRHHEHIEAYDPHKGEDNRRRLTGRHETSTIDDFSSGVANRGASIRIPRQ 589
YIEEAIEK+SKRH HI AYDP G DN RRLTG HETS I+DFS+GVANR ASIRIPR
Sbjct: 269 YIEEAIEKLSKRHQYHIRAYDPKGGLDNARRLTGFHETSNINDFSAGVANRSASIRIPRT 328
Query: 590 VSEDGFGYLEDRRPSSNCDPYSVTERIVRTTILED 694
V ++ GY EDRRPS+NCDP+SVTE ++RT +L +
Sbjct: 329 VGQEKKGYFEDRRPSANCDPFSVTEALIRTCLLNE 363
>sp|P20478|GLNA2_DROME Glutamine synthetase 2, cytoplasmic (Glutamate--ammonia ligase 2)
Length = 369
Score = 346 bits (888), Expect = 4e-95
Identities = 153/215 (71%), Positives = 185/215 (86%)
Frame = +2
Query: 50 WPKLGFPGAQGPYYCGVGCNKVFGRDIIEAHYKACLFAGIKIAGTNAEVMPAQWEFQIGP 229
WPK GFPG QGPYYCGVG NKV+ RDI++AHY+ACL+AGIK++GTNAEVMPAQWEFQ+GP
Sbjct: 155 WPKNGFPGPQGPYYCGVGANKVYARDIVDAHYRACLYAGIKVSGTNAEVMPAQWEFQVGP 214
Query: 230 CEGINVSDHLWMARYLLHRVAEDFGVVVSFDPKPIAGDWNGAGAHTNYSTIQMRSPGGIK 409
CEGI++ D LWMAR+LLHR++E+FG+V + DPKP+ GDWNGAGAHTN ST MR GGI+
Sbjct: 215 CEGISIGDDLWMARFLLHRISEEFGIVSTLDPKPMPGDWNGAGAHTNVSTKAMREDGGIR 274
Query: 410 YIEEAIEKMSKRHHEHIEAYDPHKGEDNRRRLTGRHETSTIDDFSSGVANRGASIRIPRQ 589
IE+A+ K+SK H HI AYDP +G+DN RRLTG+HETS+I+DFS+GVANRG SIRIPR
Sbjct: 275 DIEKAVAKLSKCHERHIRAYDPKQGQDNARRLTGKHETSSINDFSAGVANRGCSIRIPRG 334
Query: 590 VSEDGFGYLEDRRPSSNCDPYSVTERIVRTTILED 694
V++DG GY EDRRPSSNCDPYSV E I+RT L++
Sbjct: 335 VNDDGKGYFEDRRPSSNCDPYSVVEAILRTICLDE 369
>sp|Q4R7U3|GLNA_MACFA Glutamine synthetase (Glutamate--ammonia ligase) (GS)
Length = 374
Score = 346 bits (888), Expect = 4e-95
Identities = 154/215 (71%), Positives = 182/215 (84%)
Frame = +2
Query: 50 WPKLGFPGAQGPYYCGVGCNKVFGRDIIEAHYKACLFAGIKIAGTNAEVMPAQWEFQIGP 229
WP GFPG QGPYYCGVG ++ +GRDI+EAHY+ACL+AG+KIAGTNAEVMPAQWEFQIGP
Sbjct: 150 WPSNGFPGPQGPYYCGVGADRAYGRDIVEAHYRACLYAGVKIAGTNAEVMPAQWEFQIGP 209
Query: 230 CEGINVSDHLWMARYLLHRVAEDFGVVVSFDPKPIAGDWNGAGAHTNYSTIQMRSPGGIK 409
CEGI++ DHLW+AR++LHRV EDFGV+ +FDPKPI G+WNGAG HTN+ST MR G+K
Sbjct: 210 CEGISMGDHLWVARFILHRVCEDFGVIATFDPKPIPGNWNGAGCHTNFSTKAMREENGLK 269
Query: 410 YIEEAIEKMSKRHHEHIEAYDPHKGEDNRRRLTGRHETSTIDDFSSGVANRGASIRIPRQ 589
YIEEAIEK+SKRH HI AYDP G DN RRLTG HETS I+DFS+GVANR ASIRIPR
Sbjct: 270 YIEEAIEKLSKRHQYHIRAYDPKGGLDNARRLTGFHETSNINDFSAGVANRSASIRIPRT 329
Query: 590 VSEDGFGYLEDRRPSSNCDPYSVTERIVRTTILED 694
V ++ GY EDRRPS+NCDP+SVTE ++RT +L +
Sbjct: 330 VGQEKKGYFEDRRPSANCDPFSVTEALIRTCLLNE 364
>sp|P46410|GLNA_PIG Glutamine synthetase (Glutamate--ammonia ligase) (GS)
Length = 373
Score = 345 bits (884), Expect = 1e-94
Identities = 154/215 (71%), Positives = 181/215 (84%)
Frame = +2
Query: 50 WPKLGFPGAQGPYYCGVGCNKVFGRDIIEAHYKACLFAGIKIAGTNAEVMPAQWEFQIGP 229
WP GFPG QGPYYCGVG +K +GRDI+EAHY+ACL+AGIKI GTNAEVMPAQWEFQIGP
Sbjct: 149 WPSNGFPGPQGPYYCGVGADKAYGRDIVEAHYRACLYAGIKIGGTNAEVMPAQWEFQIGP 208
Query: 230 CEGINVSDHLWMARYLLHRVAEDFGVVVSFDPKPIAGDWNGAGAHTNYSTIQMRSPGGIK 409
CEGI++ DHLW+AR++LHRV EDFGV+ +FDPKPI G+WNGAG HTN+ST MR G+K
Sbjct: 209 CEGIDMGDHLWVARFILHRVCEDFGVIATFDPKPIPGNWNGAGCHTNFSTKAMREENGLK 268
Query: 410 YIEEAIEKMSKRHHEHIEAYDPHKGEDNRRRLTGRHETSTIDDFSSGVANRGASIRIPRQ 589
YIEEAIEK+SKRH HI AYDP G DN RRLTG HETS I+DFS+GVANRGASIRIPR
Sbjct: 269 YIEEAIEKLSKRHQYHIRAYDPKGGLDNTRRLTGFHETSNINDFSAGVANRGASIRIPRT 328
Query: 590 VSEDGFGYLEDRRPSSNCDPYSVTERIVRTTILED 694
++ GY EDRRPS+NCDP++VTE ++RT +L +
Sbjct: 329 GGQEKKGYFEDRRPSANCDPFAVTEALIRTCLLNE 363
>sp|P15105|GLNA_MOUSE Glutamine synthetase (Glutamate--ammonia ligase) (GS)
Length = 373
Score = 344 bits (882), Expect = 2e-94
Identities = 154/215 (71%), Positives = 180/215 (83%)
Frame = +2
Query: 50 WPKLGFPGAQGPYYCGVGCNKVFGRDIIEAHYKACLFAGIKIAGTNAEVMPAQWEFQIGP 229
WP GFPG QGPYYCGVG +K +GRDI+EAHY+ACL+AG+KI GTNAEVMPAQWEFQIGP
Sbjct: 149 WPSNGFPGPQGPYYCGVGADKAYGRDIVEAHYRACLYAGVKITGTNAEVMPAQWEFQIGP 208
Query: 230 CEGINVSDHLWMARYLLHRVAEDFGVVVSFDPKPIAGDWNGAGAHTNYSTIQMRSPGGIK 409
CEGI + DHLW+AR++LHRV EDFGV+ +FDPKPI G+WNGAG HTN+ST MR G+K
Sbjct: 209 CEGIRMGDHLWIARFILHRVCEDFGVIATFDPKPIPGNWNGAGCHTNFSTKAMREENGLK 268
Query: 410 YIEEAIEKMSKRHHEHIEAYDPHKGEDNRRRLTGRHETSTIDDFSSGVANRGASIRIPRQ 589
+IEEAI+K+SKRH HI AYDP G DN R LTG HETS I+DFS+GVANRGASIRIPR
Sbjct: 269 WIEEAIDKLSKRHQYHIRAYDPKGGLDNARALTGFHETSNINDFSAGVANRGASIRIPRT 328
Query: 590 VSEDGFGYLEDRRPSSNCDPYSVTERIVRTTILED 694
V ++ GY EDRRPS+NCDPY+VTE IVRT +L +
Sbjct: 329 VGQEKKGYFEDRRPSANCDPYAVTEAIVRTCLLNE 363
>sp|P16580|GLNA_CHICK Glutamine synthetase (Glutamate--ammonia ligase) (GS)
Length = 373
Score = 343 bits (880), Expect = 3e-94
Identities = 154/215 (71%), Positives = 180/215 (83%)
Frame = +2
Query: 50 WPKLGFPGAQGPYYCGVGCNKVFGRDIIEAHYKACLFAGIKIAGTNAEVMPAQWEFQIGP 229
WP FPG QGPYYCGVG +K +GRDI+EAHY+ACL+AG+KI GTNAEVMPAQWEFQ+GP
Sbjct: 149 WPSNCFPGPQGPYYCGVGADKAYGRDIVEAHYRACLYAGVKIGGTNAEVMPAQWEFQVGP 208
Query: 230 CEGINVSDHLWMARYLLHRVAEDFGVVVSFDPKPIAGDWNGAGAHTNYSTIQMRSPGGIK 409
CEGI + DHLW+AR++LHRV EDFGV+VSFDPKPI G+WNGAG HTN+ST MR GG+K
Sbjct: 209 CEGIEMGDHLWIARFILHRVCEDFGVIVSFDPKPIPGNWNGAGCHTNFSTKNMREDGGLK 268
Query: 410 YIEEAIEKMSKRHHEHIEAYDPHKGEDNRRRLTGRHETSTIDDFSSGVANRGASIRIPRQ 589
+IEEAIEK+SKRH HI AYDP G DN RRLTG HETS+I +FS+GVANRGASIRIPR
Sbjct: 269 HIEEAIEKLSKRHQYHIRAYDPKGGLDNARRLTGFHETSSIHEFSAGVANRGASIRIPRN 328
Query: 590 VSEDGFGYLEDRRPSSNCDPYSVTERIVRTTILED 694
V + GY EDR PS+NCDPY+VTE +VRT +L +
Sbjct: 329 VGHEKKGYFEDRGPSANCDPYAVTEALVRTCLLNE 363
>sp|Q04831|GLNA_PANAR Glutamine synthetase (Glutamate--ammonia ligase)
Length = 361
Score = 341 bits (874), Expect = 2e-93
Identities = 156/215 (72%), Positives = 181/215 (84%)
Frame = +2
Query: 50 WPKLGFPGAQGPYYCGVGCNKVFGRDIIEAHYKACLFAGIKIAGTNAEVMPAQWEFQIGP 229
WPK G+PG QGPYYCGVG N+V+GRD++EAHY+ACL AGI I+G NA+VMPAQWEFQ+GP
Sbjct: 146 WPKNGYPGPQGPYYCGVGANRVYGRDVVEAHYRACLCAGINISGENAKVMPAQWEFQVGP 205
Query: 230 CEGINVSDHLWMARYLLHRVAEDFGVVVSFDPKPIAGDWNGAGAHTNYSTIQMRSPGGIK 409
CEGI + D LWMARYLLHRVAEDF VVV+ DPKPI GDWNGAG HTN+ST MR P GI
Sbjct: 206 CEGITMGDDLWMARYLLHRVAEDFDVVVTLDPKPIPGDWNGAGMHTNFSTEAMRGPNGIL 265
Query: 410 YIEEAIEKMSKRHHEHIEAYDPHKGEDNRRRLTGRHETSTIDDFSSGVANRGASIRIPRQ 589
IE AI+K+SK H +HI+AYDPH G+DN RRLTG +ETS+I DFS+GVANRGASIRIPR
Sbjct: 266 EIESAIDKLSKVHEKHIKAYDPHAGKDNERRLTGHYETSSIHDFSAGVANRGASIRIPRG 325
Query: 590 VSEDGFGYLEDRRPSSNCDPYSVTERIVRTTILED 694
V+E+ GYLEDRRPSSN DPY V+ER+VRT L +
Sbjct: 326 VAEEKTGYLEDRRPSSNADPYVVSERLVRTICLNE 360
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 90,695,998
Number of Sequences: 369166
Number of extensions: 1905595
Number of successful extensions: 5504
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5157
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5417
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 7425705210
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)