Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_007_J12
(555 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q01406|SRC8_CHICK Src substrate protein p85 (p80) (Corta... 81 2e-15
sp|Q60598|SRC8_MOUSE Src substrate cortactin 75 1e-13
sp|Q14247|SRC8_HUMAN Src substrate cortactin (Amplaxin) (On... 72 7e-13
sp|P14317|HCLS1_HUMAN Hematopoietic lineage cell-specific p... 71 2e-12
sp|P49710|HCLS1_MOUSE Hematopoietic lineage cell-specific p... 67 4e-11
sp|Q925Q9|SH3K1_RAT SH3-domain kinase binding protein 1 (SH... 66 5e-11
sp|Q8R550|SH3K1_MOUSE SH3-domain kinase binding protein 1 (... 65 9e-11
sp|P43603|YFJ4_YEAST Hypothetical 40.4 kDa protein in PES4-... 64 2e-10
sp|Q96B97|SH3K1_HUMAN SH3-domain kinase binding protein 1 (... 64 3e-10
sp|Q9UJU6|DBNL_HUMAN Drebrin-like protein (SH3 domain-conta... 64 3e-10
>sp|Q01406|SRC8_CHICK Src substrate protein p85 (p80) (Cortactin)
Length = 563
Score = 80.9 bits (198), Expect = 2e-15
Identities = 45/145 (31%), Positives = 75/145 (51%), Gaps = 4/145 (2%)
Frame = +1
Query: 40 KSALGWDTEQVSKN----VSHQNEPDVPTATVTKKIEQLSVKEDIRIEKQSSNDPVEPVA 207
+ A+ +D E KN S ++EP+ T ++ + + E ++ V VA
Sbjct: 431 QDAVSYDAESAYKNSSTTYSAEHEPESGYKTTGSDYQEAVSQREAEYEPET----VYEVA 486
Query: 208 GYGEEHHSHDIEETEPQHNFETNQSSDEGLIAVALFDFDGEEEDEVNFAAGDTITHIEKI 387
G G+ + + + N ++ G+ A+AL+D+ +DE++F D IT+IE I
Sbjct: 487 GAGDHYQAEE--------NTYDEYENELGITAIALYDYQAAGDDEISFDPDDIITNIEMI 538
Query: 388 DSGWWVGVINGRKGMFPSNYVEINE 462
D GWW GV GR G+FP+NYVE+ +
Sbjct: 539 DDGWWRGVCKGRYGLFPANYVELRQ 563
Score = 45.8 bits (107), Expect = 7e-05
Identities = 21/35 (60%), Positives = 27/35 (77%)
Frame = +1
Query: 1 FGGKFGVQSDRQDKSALGWDTEQVSKNVSHQNEPD 105
FGGKFGVQ+DRQDK ALGWD ++ K H+++ D
Sbjct: 241 FGGKFGVQTDRQDKCALGWDHQE--KVQLHESQKD 273
Score = 40.4 bits (93), Expect = 0.003
Identities = 19/33 (57%), Positives = 28/33 (84%), Gaps = 1/33 (3%)
Frame = +1
Query: 1 FGGKFGVQSDRQDKSALGWD-TEQVSKNVSHQN 96
FGGKFGVQ++RQD SA+G+D E+++K+ S Q+
Sbjct: 278 FGGKFGVQTERQDPSAVGFDYKEKLAKHESQQD 310
Score = 40.0 bits (92), Expect = 0.004
Identities = 18/35 (51%), Positives = 26/35 (74%)
Frame = +1
Query: 1 FGGKFGVQSDRQDKSALGWDTEQVSKNVSHQNEPD 105
FGGK+GVQ+DR DKSA+G+D + K H+++ D
Sbjct: 167 FGGKYGVQADRVDKSAVGFDYQ--GKTEKHESQKD 199
Score = 37.0 bits (84), Expect = 0.033
Identities = 18/35 (51%), Positives = 24/35 (68%)
Frame = +1
Query: 1 FGGKFGVQSDRQDKSALGWDTEQVSKNVSHQNEPD 105
FGGKFGVQ+DR D+SA+G+ E K H ++ D
Sbjct: 130 FGGKFGVQTDRVDQSAVGF--EYQGKTEKHASQKD 162
Score = 35.0 bits (79), Expect = 0.12
Identities = 16/35 (45%), Positives = 23/35 (65%)
Frame = +1
Query: 1 FGGKFGVQSDRQDKSALGWDTEQVSKNVSHQNEPD 105
FGGK+GV D+ DKSA+G+ E K H+++ D
Sbjct: 204 FGGKYGVDKDKVDKSAVGF--EYQGKTEKHESQKD 236
Score = 34.7 bits (78), Expect = 0.16
Identities = 16/30 (53%), Positives = 24/30 (80%), Gaps = 1/30 (3%)
Frame = +1
Query: 1 FGGKFGVQSDRQDKSALGWDTE-QVSKNVS 87
+GGKFGV+ DR DKSA+G + + ++SK+ S
Sbjct: 93 YGGKFGVEQDRMDKSAVGHEYQSKLSKHCS 122
Score = 33.1 bits (74), Expect = 0.47
Identities = 16/45 (35%), Positives = 24/45 (53%)
Frame = +1
Query: 1 FGGKFGVQSDRQDKSALGWDTEQVSKNVSHQNEPDVPTATVTKKI 135
FGGK+GVQ DR DK+A ++ + + + +P A T I
Sbjct: 315 FGGKYGVQKDRMDKNAATFEDIEKPTSTYQKTKPVERVANKTSSI 359
>sp|Q60598|SRC8_MOUSE Src substrate cortactin
Length = 546
Score = 74.7 bits (182), Expect = 1e-13
Identities = 44/146 (30%), Positives = 70/146 (47%), Gaps = 1/146 (0%)
Frame = +1
Query: 28 DRQDKSALGWDTEQVSKNVSHQ-NEPDVPTATVTKKIEQLSVKEDIRIEKQSSNDPVEPV 204
DR S + D S++ +EP+ + I + ++ + + + E
Sbjct: 413 DRPPSSPIYEDAAPFKAEPSYRGSEPEPEYSIEAAGIPEAGSQQGLTYTSEPVYETTEAP 472
Query: 205 AGYGEEHHSHDIEETEPQHNFETNQSSDEGLIAVALFDFDGEEEDEVNFAAGDTITHIEK 384
Y E ++D E SD G+ A+AL+D+ +DE++F D IT+IE
Sbjct: 473 GHYQAEDDTYDGYE------------SDLGITAIALYDYQAAGDDEISFDPDDIITNIEM 520
Query: 385 IDSGWWVGVINGRKGMFPSNYVEINE 462
ID GWW GV GR G+FP+NYVE+ +
Sbjct: 521 IDDGWWRGVCKGRYGLFPANYVELRQ 546
Score = 47.0 bits (110), Expect = 3e-05
Identities = 22/38 (57%), Positives = 28/38 (73%)
Frame = +1
Query: 1 FGGKFGVQSDRQDKSALGWDTEQVSKNVSHQNEPDVPT 114
FGGKFGVQ+DRQDK ALGWD ++ K H+++ D T
Sbjct: 232 FGGKFGVQTDRQDKCALGWDHQE--KLQLHESQKDYKT 267
Score = 40.0 bits (92), Expect = 0.004
Identities = 18/35 (51%), Positives = 26/35 (74%)
Frame = +1
Query: 1 FGGKFGVQSDRQDKSALGWDTEQVSKNVSHQNEPD 105
FGGK+GVQ+DR DKSA+G+D + K H+++ D
Sbjct: 158 FGGKYGVQADRVDKSAVGFDYQ--GKTEKHESQKD 190
Score = 40.0 bits (92), Expect = 0.004
Identities = 19/33 (57%), Positives = 27/33 (81%), Gaps = 1/33 (3%)
Frame = +1
Query: 1 FGGKFGVQSDRQDKSALGWD-TEQVSKNVSHQN 96
FGGKFGVQS+RQD SA+G+D E+++K+ Q+
Sbjct: 269 FGGKFGVQSERQDSSAVGFDYKERLAKHEPQQD 301
Score = 36.2 bits (82), Expect = 0.056
Identities = 18/35 (51%), Positives = 23/35 (65%)
Frame = +1
Query: 1 FGGKFGVQSDRQDKSALGWDTEQVSKNVSHQNEPD 105
FGGKFGVQ DR D+SA+G+ E K H ++ D
Sbjct: 121 FGGKFGVQMDRVDQSAVGF--EYQGKTEKHASQKD 153
Score = 34.7 bits (78), Expect = 0.16
Identities = 15/35 (42%), Positives = 23/35 (65%)
Frame = +1
Query: 1 FGGKFGVQSDRQDKSALGWDTEQVSKNVSHQNEPD 105
FGGK+G+ D+ DKSA+G+ E K H+++ D
Sbjct: 195 FGGKYGIDKDKVDKSAVGF--EYQGKTEKHESQKD 227
Score = 34.7 bits (78), Expect = 0.16
Identities = 24/90 (26%), Positives = 37/90 (41%)
Frame = +1
Query: 1 FGGKFGVQSDRQDKSALGWDTEQVSKNVSHQNEPDVPTATVTKKIEQLSVKEDIRIEKQS 180
FGGK+GVQ DR DK+A T + V + VP VT K + + +++
Sbjct: 306 FGGKYGVQKDRMDKNA---STFEEVVQVPSAYQKTVPIEAVTSKTSNIRANFENLAKERE 362
Query: 181 SNDPVEPVAGYGEEHHSHDIEETEPQHNFE 270
D + A + E+ E + E
Sbjct: 363 QEDRRKAEAERAQRMAKERQEQEEARRKLE 392
Score = 33.5 bits (75), Expect = 0.36
Identities = 15/30 (50%), Positives = 24/30 (80%), Gaps = 1/30 (3%)
Frame = +1
Query: 1 FGGKFGVQSDRQDKSALGWDTE-QVSKNVS 87
+GGKFGV+ DR D+SA+G + + ++SK+ S
Sbjct: 84 YGGKFGVEQDRMDRSAVGHEYQSKLSKHCS 113
>sp|Q14247|SRC8_HUMAN Src substrate cortactin (Amplaxin) (Oncogene EMS1)
Length = 550
Score = 72.4 bits (176), Expect = 7e-13
Identities = 31/60 (51%), Positives = 42/60 (70%)
Frame = +1
Query: 283 SDEGLIAVALFDFDGEEEDEVNFAAGDTITHIEKIDSGWWVGVINGRKGMFPSNYVEINE 462
+D G AVAL+D+ +DE++F D IT+IE ID GWW GV GR G+FP+NYVE+ +
Sbjct: 491 NDLGYTAVALYDYQAAGDDEISFDPDDIITNIEMIDDGWWRGVCKGRYGLFPANYVELRQ 550
Score = 47.0 bits (110), Expect = 3e-05
Identities = 22/38 (57%), Positives = 28/38 (73%)
Frame = +1
Query: 1 FGGKFGVQSDRQDKSALGWDTEQVSKNVSHQNEPDVPT 114
FGGKFGVQ+DRQDK ALGWD ++ K H+++ D T
Sbjct: 232 FGGKFGVQTDRQDKCALGWDHQE--KLQLHESQKDYKT 267
Score = 40.8 bits (94), Expect = 0.002
Identities = 19/33 (57%), Positives = 28/33 (84%), Gaps = 1/33 (3%)
Frame = +1
Query: 1 FGGKFGVQSDRQDKSALGWD-TEQVSKNVSHQN 96
FGGKFGVQS+RQD +A+G+D E+++K+ S Q+
Sbjct: 269 FGGKFGVQSERQDSAAVGFDYKEKLAKHESQQD 301
Score = 39.7 bits (91), Expect = 0.005
Identities = 18/35 (51%), Positives = 26/35 (74%)
Frame = +1
Query: 1 FGGKFGVQSDRQDKSALGWDTEQVSKNVSHQNEPD 105
FGGK+GVQ+DR DKSA+G+D + K H+++ D
Sbjct: 158 FGGKYGVQADRVDKSAVGFDYQ--GKTEKHESQRD 190
Score = 37.4 bits (85), Expect = 0.025
Identities = 23/63 (36%), Positives = 32/63 (50%), Gaps = 1/63 (1%)
Frame = +1
Query: 1 FGGKFGVQSDRQDKSALGWDTEQVSKNVSHQNEPDVPTATVTKKIEQLSVK-EDIRIEKQ 177
FGGK+GVQ DR DK+A T + VS + VP VT K + E++ EK+
Sbjct: 306 FGGKYGVQKDRMDKNA---STFEDVTQVSSAYQKTVPVEAVTSKTSNIRANFENLAKEKE 362
Query: 178 SSN 186
+
Sbjct: 363 QED 365
Score = 36.2 bits (82), Expect = 0.056
Identities = 18/35 (51%), Positives = 23/35 (65%)
Frame = +1
Query: 1 FGGKFGVQSDRQDKSALGWDTEQVSKNVSHQNEPD 105
FGGKFGVQ DR D+SA+G+ E K H ++ D
Sbjct: 121 FGGKFGVQMDRVDQSAVGF--EYQGKTEKHASQKD 153
Score = 34.7 bits (78), Expect = 0.16
Identities = 16/30 (53%), Positives = 24/30 (80%), Gaps = 1/30 (3%)
Frame = +1
Query: 1 FGGKFGVQSDRQDKSALGWDTE-QVSKNVS 87
+GGKFGV+ DR DKSA+G + + ++SK+ S
Sbjct: 84 YGGKFGVEQDRMDKSAVGHEYQSKLSKHCS 113
Score = 34.7 bits (78), Expect = 0.16
Identities = 15/35 (42%), Positives = 23/35 (65%)
Frame = +1
Query: 1 FGGKFGVQSDRQDKSALGWDTEQVSKNVSHQNEPD 105
FGGK+G+ D+ DKSA+G+ E K H+++ D
Sbjct: 195 FGGKYGIDKDKVDKSAVGF--EYQGKTEKHESQKD 227
>sp|P14317|HCLS1_HUMAN Hematopoietic lineage cell-specific protein (Hematopoietic
cell-specific LYN substrate 1) (LckBP1) (p75)
Length = 486
Score = 71.2 bits (173), Expect = 2e-12
Identities = 47/147 (31%), Positives = 71/147 (48%), Gaps = 29/147 (19%)
Frame = +1
Query: 109 PTATVTKKIEQLSVKEDIRIEKQSSNDPV---EPVAGYG--EEHHSHDIEETEPQHNFET 273
P A + +E L V+E+ E + +P EP Y EE H+ +E EP+ ++E
Sbjct: 341 PPALPPRTLEGLQVEEEPVYEAEPEPEPEPEPEPENDYEDVEEMDRHE-QEDEPEGDYEE 399
Query: 274 NQSSDE------------------------GLIAVALFDFDGEEEDEVNFAAGDTITHIE 381
++ G+ AVAL+D+ GE DE++F D IT IE
Sbjct: 400 VLEPEDSSFSSALAGSSGCPAGAGAGAVALGISAVALYDYQGEGSDELSFDPDDVITDIE 459
Query: 382 KIDSGWWVGVINGRKGMFPSNYVEINE 462
+D GWW G +G G+FP+NYV++ E
Sbjct: 460 MVDEGWWRGRCHGHFGLFPANYVKLLE 486
Score = 37.4 bits (85), Expect = 0.025
Identities = 17/33 (51%), Positives = 26/33 (78%), Gaps = 1/33 (3%)
Frame = +1
Query: 1 FGGKFGVQSDRQDKSALGWDTE-QVSKNVSHQN 96
FGGK+GV+ DR DKSA+G+D + +V K+ S ++
Sbjct: 120 FGGKYGVERDRADKSAVGFDYKGEVEKHTSQKD 152
Score = 35.4 bits (80), Expect = 0.095
Identities = 25/104 (24%), Positives = 40/104 (38%)
Frame = +1
Query: 1 FGGKFGVQSDRQDKSALGWDTEQVSKNVSHQNEPDVPTATVTKKIEQLSVKEDIRIEKQS 180
FGG++G+Q DR DKSA+G+ NE + PT K + R K
Sbjct: 194 FGGQYGIQKDRVDKSAVGF------------NEMEAPTTAYKKTTPIEAASSGARGLKAK 241
Query: 181 SNDPVEPVAGYGEEHHSHDIEETEPQHNFETNQSSDEGLIAVAL 312
E EE + + + + T +S + +A+
Sbjct: 242 FESMAEEKRKREEEEKAQQVARRQQERKAVTKRSPEAPQPVIAM 285
Score = 34.3 bits (77), Expect = 0.21
Identities = 16/35 (45%), Positives = 24/35 (68%)
Frame = +1
Query: 1 FGGKFGVQSDRQDKSALGWDTEQVSKNVSHQNEPD 105
+GG+FGV+ DR DKSA+G E V++ H ++ D
Sbjct: 83 YGGRFGVERDRMDKSAVG--HEYVAEVEKHSSQTD 115
Score = 34.3 bits (77), Expect = 0.21
Identities = 14/35 (40%), Positives = 25/35 (71%)
Frame = +1
Query: 1 FGGKFGVQSDRQDKSALGWDTEQVSKNVSHQNEPD 105
FGG++GV+ D+ DK+ALG+D + + H+++ D
Sbjct: 157 FGGRYGVEKDKWDKAALGYDYK--GETEKHESQRD 189
>sp|P49710|HCLS1_MOUSE Hematopoietic lineage cell-specific protein (Hematopoietic
cell-specific LYN substrate 1) (LckBP1)
Length = 486
Score = 66.6 bits (161), Expect = 4e-11
Identities = 30/74 (40%), Positives = 45/74 (60%), Gaps = 3/74 (4%)
Frame = +1
Query: 244 ETEPQHNFETNQSSDEG---LIAVALFDFDGEEEDEVNFAAGDTITHIEKIDSGWWVGVI 414
E P +++ S+ G + A+AL+D+ GE DE++F D IT IE +D GWW G
Sbjct: 412 EDTPSLSYQAGPSAGAGGAGISAIALYDYQGEGSDELSFDPDDIITDIEMVDEGWWRGQC 471
Query: 415 NGRKGMFPSNYVEI 456
G G+FP+NYV++
Sbjct: 472 RGHFGLFPANYVKL 485
Score = 37.4 bits (85), Expect = 0.025
Identities = 17/33 (51%), Positives = 26/33 (78%), Gaps = 1/33 (3%)
Frame = +1
Query: 1 FGGKFGVQSDRQDKSALGWDTE-QVSKNVSHQN 96
FGGK+GV+ DR DKSA+G+D + +V K+ S ++
Sbjct: 120 FGGKYGVERDRADKSAVGFDYKGEVEKHASQKD 152
Score = 35.4 bits (80), Expect = 0.095
Identities = 14/35 (40%), Positives = 26/35 (74%)
Frame = +1
Query: 1 FGGKFGVQSDRQDKSALGWDTEQVSKNVSHQNEPD 105
FGG++GV+ D++DK+ALG+D + + H+++ D
Sbjct: 157 FGGRYGVEKDKRDKAALGYDYK--GETEKHESQRD 189
Score = 33.9 bits (76), Expect = 0.28
Identities = 19/66 (28%), Positives = 38/66 (57%), Gaps = 5/66 (7%)
Frame = +1
Query: 1 FGGKFGVQSDRQDKSALGWDTEQVSKNVSHQNEPDVPTAT-----VTKKIEQLSVKEDIR 165
FGG++G+Q DR DKSA+G++ E + +++ + A+ + K E L+ ++ R
Sbjct: 194 FGGQYGIQKDRVDKSAVGFN-EMEAPTTAYKKTTPIEAASSGARGLKAKFESLAEEKRKR 252
Query: 166 IEKQSS 183
E++ +
Sbjct: 253 EEEEKA 258
Score = 33.1 bits (74), Expect = 0.47
Identities = 16/35 (45%), Positives = 23/35 (65%)
Frame = +1
Query: 1 FGGKFGVQSDRQDKSALGWDTEQVSKNVSHQNEPD 105
+GG+FGV+ DR DKSA+G E V+ H ++ D
Sbjct: 83 YGGQFGVERDRMDKSAVG--HEYVADVEKHSSQTD 115
>sp|Q925Q9|SH3K1_RAT SH3-domain kinase binding protein 1 (SH3 containing, expressed in
tumorigenic astrocytes) (Regulator of ubiquitous kinase)
(Ruk)
Length = 709
Score = 66.2 bits (160), Expect = 5e-11
Identities = 31/67 (46%), Positives = 44/67 (65%), Gaps = 1/67 (1%)
Frame = +1
Query: 301 AVALFDFDGEEEDEVNFAAGDTITHIEKIDSGWWVGVINGRKGMFPSNYV-EINE*KKIY 477
A+ FD+ + +DE+ + G+ IT+I K D GWW G INGR+G+FP N+V EI K +
Sbjct: 4 AIVEFDYQAQHDDELTISVGEVITNIRKEDGGWWEGQINGRRGLFPDNFVREIK--KDVK 61
Query: 478 KHLLINR 498
K LL N+
Sbjct: 62 KDLLSNK 68
Score = 55.8 bits (133), Expect = 7e-08
Identities = 22/51 (43%), Positives = 35/51 (68%), Gaps = 2/51 (3%)
Frame = +1
Query: 310 LFDFDGEEEDEVNFAAGDTITHIEK--IDSGWWVGVINGRKGMFPSNYVEI 456
+F ++ + +DE+ GD +T I K ID GWW G +NGR+G+FP N+V++
Sbjct: 319 IFPYEAQNDDELTIKEGDIVTLINKDCIDVGWWEGELNGRRGVFPDNFVKL 369
Score = 55.1 bits (131), Expect = 1e-07
Identities = 28/107 (26%), Positives = 52/107 (48%), Gaps = 5/107 (4%)
Frame = +1
Query: 148 VKEDIRIEKQSSNDPVEPVAGYGEEHHSHDIEETEPQHNFET-----NQSSDEGLIAVAL 312
+K+D++ + S+ P +P+ HD+ + ET +
Sbjct: 56 IKKDVKKDLLSNKAPEKPM---------HDVSSGNSLLSSETILRTNKRGERRRRRCQVA 106
Query: 313 FDFDGEEEDEVNFAAGDTITHIEKIDSGWWVGVINGRKGMFPSNYVE 453
F + + +DE+ GD I + +++ GWW GV+NG+ GMFPSN+++
Sbjct: 107 FSYLPQNDDELELKVGDIIEVVGEVEEGWWEGVLNGKTGMFPSNFIK 153
>sp|Q8R550|SH3K1_MOUSE SH3-domain kinase binding protein 1 (SH3 containing, expressed in
tumorigenic astrocytes) (Regulator of ubiquitous kinase)
(Ruk)
Length = 709
Score = 65.5 bits (158), Expect = 9e-11
Identities = 31/67 (46%), Positives = 44/67 (65%), Gaps = 1/67 (1%)
Frame = +1
Query: 301 AVALFDFDGEEEDEVNFAAGDTITHIEKIDSGWWVGVINGRKGMFPSNYV-EINE*KKIY 477
A+ FD+ + +DE+ + G+ IT+I K D GWW G INGR+G+FP N+V EI K +
Sbjct: 4 AIVEFDYQAQHDDELTISVGEVITNIRKEDGGWWEGQINGRRGLFPDNFVREIK--KDMK 61
Query: 478 KHLLINR 498
K LL N+
Sbjct: 62 KDLLSNK 68
Score = 55.8 bits (133), Expect = 7e-08
Identities = 22/51 (43%), Positives = 35/51 (68%), Gaps = 2/51 (3%)
Frame = +1
Query: 310 LFDFDGEEEDEVNFAAGDTITHIEK--IDSGWWVGVINGRKGMFPSNYVEI 456
+F ++ + +DE+ GD +T I K ID GWW G +NGR+G+FP N+V++
Sbjct: 319 IFPYEAQNDDELTIKEGDIVTLINKDCIDVGWWEGELNGRRGVFPDNFVKL 369
Score = 54.3 bits (129), Expect = 2e-07
Identities = 28/107 (26%), Positives = 52/107 (48%), Gaps = 5/107 (4%)
Frame = +1
Query: 148 VKEDIRIEKQSSNDPVEPVAGYGEEHHSHDIEETEPQHNFET-----NQSSDEGLIAVAL 312
+K+D++ + S+ P +P+ HD+ + ET +
Sbjct: 56 IKKDMKKDLLSNKAPEKPM---------HDVSSGNALLSSETILRTNKRGERRRRRCQVA 106
Query: 313 FDFDGEEEDEVNFAAGDTITHIEKIDSGWWVGVINGRKGMFPSNYVE 453
F + + +DE+ GD I + +++ GWW GV+NG+ GMFPSN+++
Sbjct: 107 FSYLPQNDDELELKVGDIIEVVGEVEEGWWEGVLNGKTGMFPSNFIK 153
>sp|P43603|YFJ4_YEAST Hypothetical 40.4 kDa protein in PES4-HIS2 intergenic region
Length = 373
Score = 63.9 bits (154), Expect = 2e-10
Identities = 29/54 (53%), Positives = 39/54 (72%), Gaps = 2/54 (3%)
Frame = +1
Query: 301 AVALFDFDGEEEDEVNFAAGDTITHIEKIDS--GWWVGVINGRKGMFPSNYVEI 456
AVAL+ F GEE ++ F GD IT ++K DS WW G +NGR+G+FP+NYVE+
Sbjct: 319 AVALYSFAGEESGDLPFRKGDVITILKKSDSQNDWWTGRVNGREGIFPANYVEL 372
>sp|Q96B97|SH3K1_HUMAN SH3-domain kinase binding protein 1 (Cbl-interacting protein of 85
kDa) (Human Src-family kinase binding protein 1) (HSB-1)
(CD2 binding protein 3) (CD2BP3)
Length = 665
Score = 63.5 bits (153), Expect = 3e-10
Identities = 30/67 (44%), Positives = 44/67 (65%), Gaps = 1/67 (1%)
Frame = +1
Query: 301 AVALFDFDGEEEDEVNFAAGDTITHIEKIDSGWWVGVINGRKGMFPSNYV-EINE*KKIY 477
A+ FD+ + +DE+ + G+ IT+I K D GWW G INGR+G+FP N+V EI K++
Sbjct: 4 AIVEFDYQAQHDDELTISVGEIITNIRKEDGGWWEGQINGRRGLFPDNFVREIK--KEMK 61
Query: 478 KHLLINR 498
K L N+
Sbjct: 62 KDPLTNK 68
Score = 55.8 bits (133), Expect = 7e-08
Identities = 22/51 (43%), Positives = 35/51 (68%), Gaps = 2/51 (3%)
Frame = +1
Query: 310 LFDFDGEEEDEVNFAAGDTITHIEK--IDSGWWVGVINGRKGMFPSNYVEI 456
+F ++ + +DE+ GD +T I K ID GWW G +NGR+G+FP N+V++
Sbjct: 275 IFPYEAQNDDELTIKEGDIVTLINKDCIDVGWWEGELNGRRGVFPDNFVKL 325
Score = 53.9 bits (128), Expect = 3e-07
Identities = 19/47 (40%), Positives = 32/47 (68%)
Frame = +1
Query: 313 FDFDGEEEDEVNFAAGDTITHIEKIDSGWWVGVINGRKGMFPSNYVE 453
F + + +DE+ GD I + +++ GWW GV+NG+ GMFPSN+++
Sbjct: 107 FSYLPQNDDELELKVGDIIEVVGEVEEGWWEGVLNGKTGMFPSNFIK 153
>sp|Q9UJU6|DBNL_HUMAN Drebrin-like protein (SH3 domain-containing protein 7) (Drebrin F)
(Cervical SH3P7) (HPK1-interacting protein of 55 kDa)
(HIP-55) (Cervical mucin-associated protein)
Length = 430
Score = 63.5 bits (153), Expect = 3e-10
Identities = 42/122 (34%), Positives = 58/122 (47%), Gaps = 1/122 (0%)
Frame = +1
Query: 100 PDVPTATVTKKIEQLSVKEDIRIEKQSSNDPVEPVAGYGEEHHSHDIEETEPQHNFETNQ 279
P P V + E+ +E E P+ G G EH H I+
Sbjct: 319 PSTPPCLVQAE-EEAVYEEPPEQETFYEQPPLVQQQGAGSEHIDHHIQG---------QG 368
Query: 280 SSDEGLIAVALFDFDGEEEDEVNFAAGDTITHIEKIDSGWWVGV-INGRKGMFPSNYVEI 456
S +GL A AL+D+ ++ E++F + IT IE ID GWW G +G GMFP+NYVE+
Sbjct: 369 LSGQGLCARALYDYQAADDTEISFDPENLITGIEVIDEGWWRGYGPDGHFGMFPANYVEL 428
Query: 457 NE 462
E
Sbjct: 429 IE 430
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.313 0.133 0.389
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 62,427,385
Number of Sequences: 369166
Number of extensions: 1197674
Number of successful extensions: 3416
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3164
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3339
length of database: 68,354,980
effective HSP length: 104
effective length of database: 49,142,540
effective search space used: 3931403200
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)