Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_007_I16
(788 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q63699|CDK2_RAT Cell division protein kinase 2 69 1e-11
sp|P24941|CDK2_HUMAN Cell division protein kinase 2 (p33 pr... 68 3e-11
sp|O55076|CDK2_CRIGR Cell division protein kinase 2 68 3e-11
sp|P97377|CDK2_MOUSE Cell division protein kinase 2 68 3e-11
sp|P48963|CDK2_MESAU Cell division protein kinase 2 67 7e-11
sp|P43450|CDK2_CARAU Cell division protein kinase 2 66 1e-10
sp|Q80YP0|CDK3_MOUSE Truncated cell division protein kinase... 65 3e-10
sp|P23437|CDK2_XENLA Cell division protein kinase 2 (CDC2 h... 64 5e-10
sp|P29618|CDC21_ORYSA Cell division control protein 2 homol... 62 2e-09
sp|P23111|CDC2_MAIZE Cell division control protein 2 homolo... 60 5e-09
>sp|Q63699|CDK2_RAT Cell division protein kinase 2
Length = 298
Score = 68.9 bits (167), Expect = 1e-11
Identities = 41/125 (32%), Positives = 69/125 (55%), Gaps = 2/125 (1%)
Frame = +2
Query: 389 MENVTVQKKIDQGQYGKIFLCYDEISRSTVAMKKCKLEANGKLENFTGIINEIQVVSLL- 565
MEN +KI +G YG ++ ++++ VA+KK +L+ + T I + +SLL
Sbjct: 1 MENFQKVEKIGEGTYGVVYKAKNKLTGEVVALKKIRLDTETEGVPSTAI----REISLLK 56
Query: 566 -MDHPNIIKIFDFYRDEKYFCVTMEYMDQKSVRCYLDKNNNRPLPEPLIKQFSLQVLDGL 742
++HPNI+K+ D E + E++ Q ++ ++D + LP PLIK + Q+L GL
Sbjct: 57 ELNHPNIVKLLDVIHTENKLYLVFEFLHQ-DLKKFMDASALTGLPLPLIKSYLFQLLQGL 115
Query: 743 VFMHS 757
F HS
Sbjct: 116 AFCHS 120
>sp|P24941|CDK2_HUMAN Cell division protein kinase 2 (p33 protein kinase)
Length = 298
Score = 68.2 bits (165), Expect = 3e-11
Identities = 40/125 (32%), Positives = 69/125 (55%), Gaps = 2/125 (1%)
Frame = +2
Query: 389 MENVTVQKKIDQGQYGKIFLCYDEISRSTVAMKKCKLEANGKLENFTGIINEIQVVSLL- 565
MEN +KI +G YG ++ ++++ VA+KK +L+ + T I+ +SLL
Sbjct: 1 MENFQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTA----IREISLLK 56
Query: 566 -MDHPNIIKIFDFYRDEKYFCVTMEYMDQKSVRCYLDKNNNRPLPEPLIKQFSLQVLDGL 742
++HPNI+K+ D E + E++ Q ++ ++D + +P PLIK + Q+L GL
Sbjct: 57 ELNHPNIVKLLDVIHTENKLYLVFEFLHQ-DLKKFMDASALTGIPLPLIKSYLFQLLQGL 115
Query: 743 VFMHS 757
F HS
Sbjct: 116 AFCHS 120
>sp|O55076|CDK2_CRIGR Cell division protein kinase 2
Length = 298
Score = 68.2 bits (165), Expect = 3e-11
Identities = 40/125 (32%), Positives = 69/125 (55%), Gaps = 2/125 (1%)
Frame = +2
Query: 389 MENVTVQKKIDQGQYGKIFLCYDEISRSTVAMKKCKLEANGKLENFTGIINEIQVVSLL- 565
MEN +KI +G YG ++ ++++ VA+KK +L+ + T I+ +SLL
Sbjct: 1 MENFQKVEKIGEGTYGVVYKAKNKLTGEVVALKKIRLDTETEGVPSTA----IREISLLK 56
Query: 566 -MDHPNIIKIFDFYRDEKYFCVTMEYMDQKSVRCYLDKNNNRPLPEPLIKQFSLQVLDGL 742
++HPNI+K+ D E + E++ Q ++ ++D + +P PLIK + Q+L GL
Sbjct: 57 ELNHPNIVKLLDVIHTENKLYLVFEFLHQ-DLKKFMDASAVTGIPLPLIKSYLFQLLQGL 115
Query: 743 VFMHS 757
F HS
Sbjct: 116 AFCHS 120
>sp|P97377|CDK2_MOUSE Cell division protein kinase 2
Length = 346
Score = 68.2 bits (165), Expect = 3e-11
Identities = 40/125 (32%), Positives = 69/125 (55%), Gaps = 2/125 (1%)
Frame = +2
Query: 389 MENVTVQKKIDQGQYGKIFLCYDEISRSTVAMKKCKLEANGKLENFTGIINEIQVVSLL- 565
MEN +KI +G YG ++ ++++ VA+KK +L+ + T I+ +SLL
Sbjct: 1 MENFQKVEKIGEGTYGVVYKAKNKLTGEVVALKKIRLDTETEGVPSTA----IREISLLK 56
Query: 566 -MDHPNIIKIFDFYRDEKYFCVTMEYMDQKSVRCYLDKNNNRPLPEPLIKQFSLQVLDGL 742
++HPNI+K+ D E + E++ Q ++ ++D + +P PLIK + Q+L GL
Sbjct: 57 ELNHPNIVKLLDVIHTENKLYLVFEFLHQ-DLKKFMDASALTGIPLPLIKSYLFQLLQGL 115
Query: 743 VFMHS 757
F HS
Sbjct: 116 AFCHS 120
>sp|P48963|CDK2_MESAU Cell division protein kinase 2
Length = 298
Score = 66.6 bits (161), Expect = 7e-11
Identities = 40/125 (32%), Positives = 68/125 (54%), Gaps = 2/125 (1%)
Frame = +2
Query: 389 MENVTVQKKIDQGQYGKIFLCYDEISRSTVAMKKCKLEANGKLENFTGIINEIQVVSLL- 565
MEN +KI +G YG ++ ++++ VA+KK +L+ + T I+ +SLL
Sbjct: 1 MENFQKVEKIGEGTYGVVYKAKNKLTGEVVALKKIRLDTETEGVPSTA----IREISLLK 56
Query: 566 -MDHPNIIKIFDFYRDEKYFCVTMEYMDQKSVRCYLDKNNNRPLPEPLIKQFSLQVLDGL 742
++HPNI+K+ D E + E + Q ++ ++D + +P PLIK + Q+L GL
Sbjct: 57 ELNHPNIVKLLDVIHTENKLYLVFELLHQ-DLKKFMDASAVTGIPLPLIKSYLFQLLQGL 115
Query: 743 VFMHS 757
F HS
Sbjct: 116 AFCHS 120
>sp|P43450|CDK2_CARAU Cell division protein kinase 2
Length = 298
Score = 65.9 bits (159), Expect = 1e-10
Identities = 38/125 (30%), Positives = 69/125 (55%), Gaps = 2/125 (1%)
Frame = +2
Query: 389 MENVTVQKKIDQGQYGKIFLCYDEISRSTVAMKKCKLEANGKLENFTGIINEIQVVSLL- 565
ME+ +KI +G YG ++ ++++ TVA+KK +L+ + T I+ +SLL
Sbjct: 1 MESFQKVEKIGEGTYGVVYKAKNKVTGETVALKKIRLDTETEGVPSTA----IREISLLK 56
Query: 566 -MDHPNIIKIFDFYRDEKYFCVTMEYMDQKSVRCYLDKNNNRPLPEPLIKQFSLQVLDGL 742
++HPNI+K+ D E + E++ Q ++ ++D + + PL+K + Q+L GL
Sbjct: 57 ELNHPNIVKLHDVIHTENKLYLVFEFLHQ-DLKRFMDSSTVTGISLPLVKSYLFQLLQGL 115
Query: 743 VFMHS 757
F HS
Sbjct: 116 AFCHS 120
>sp|Q80YP0|CDK3_MOUSE Truncated cell division protein kinase 3 homolog
Length = 186
Score = 64.7 bits (156), Expect = 3e-10
Identities = 37/118 (31%), Positives = 66/118 (55%), Gaps = 2/118 (1%)
Frame = +2
Query: 410 KKIDQGQYGKIFLCYDEISRSTVAMKKCKLEANGKLENFTGIINEIQVVSLLMD--HPNI 583
+KI +G YG ++ ++++ VA+KK +L+ + T + + +SLL + HPNI
Sbjct: 8 EKIGEGTYGVVYKARNKVTGQLVALKKIRLDLEAEGVPSTAV----REISLLKELKHPNI 63
Query: 584 IKIFDFYRDEKYFCVTMEYMDQKSVRCYLDKNNNRPLPEPLIKQFSLQVLDGLVFMHS 757
IK+ D EK + E++ Q R ++D + LP P++K + Q+L+G+ F HS
Sbjct: 64 IKLLDVVHREKKLYMVFEFLTQDLKR-HMDSSPTSELPLPVVKSYLAQLLEGVSFCHS 120
>sp|P23437|CDK2_XENLA Cell division protein kinase 2 (CDC2 homolog Eg1 protein kinase)
Length = 297
Score = 63.9 bits (154), Expect = 5e-10
Identities = 38/125 (30%), Positives = 68/125 (54%), Gaps = 2/125 (1%)
Frame = +2
Query: 389 MENVTVQKKIDQGQYGKIFLCYDEISRSTVAMKKCKLEANGKLENFTGIINEIQVVSLL- 565
MEN +KI +G YG ++ + + VA+KK +L+ + T I+ +SLL
Sbjct: 1 MENFQKVEKIGEGTYGVVYKARNRETGEIVALKKIRLDTETEGVPSTA----IREISLLK 56
Query: 566 -MDHPNIIKIFDFYRDEKYFCVTMEYMDQKSVRCYLDKNNNRPLPEPLIKQFSLQVLDGL 742
++HPNI+K+ D E + E+++Q ++ ++D++N + L+K + Q+L GL
Sbjct: 57 ELNHPNIVKLLDVIHTENKLYLVFEFLNQ-DLKKFMDRSNISGISLALVKSYLFQLLQGL 115
Query: 743 VFMHS 757
F HS
Sbjct: 116 AFCHS 120
>sp|P29618|CDC21_ORYSA Cell division control protein 2 homolog 1
Length = 294
Score = 62.0 bits (149), Expect = 2e-09
Identities = 38/125 (30%), Positives = 65/125 (52%), Gaps = 2/125 (1%)
Frame = +2
Query: 389 MENVTVQKKIDQGQYGKIFLCYDEISRSTVAMKKCKLEANGKLENFTGIINEIQVVSLL- 565
ME ++KI +G YG ++ D+++ T+A+KK +LE + T I+ +SLL
Sbjct: 1 MEQYEKEEKIGEGTYGVVYRARDKVTNETIALKKIRLEQEDEGVPSTA----IREISLLK 56
Query: 566 -MDHPNIIKIFDFYRDEKYFCVTMEYMDQKSVRCYLDKNNNRPLPEPLIKQFSLQVLDGL 742
M H NI+++ D EK + EY+D ++ ++D LIK + Q+L G+
Sbjct: 57 EMHHGNIVRLHDVIHSEKRIYLVFEYLD-LDLKKFMDSCPEFAKNPTLIKSYLYQILRGV 115
Query: 743 VFMHS 757
+ HS
Sbjct: 116 AYCHS 120
>sp|P23111|CDC2_MAIZE Cell division control protein 2 homolog (p34cdc2)
Length = 294
Score = 60.5 bits (145), Expect = 5e-09
Identities = 38/125 (30%), Positives = 64/125 (51%), Gaps = 2/125 (1%)
Frame = +2
Query: 389 MENVTVQKKIDQGQYGKIFLCYDEISRSTVAMKKCKLEANGKLENFTGIINEIQVVSLL- 565
ME +KI +G YG ++ D+ + T+A+KK +LE + T I+ +SLL
Sbjct: 1 MEQYEKVEKIGEGTYGVVYKALDKATNETIALKKIRLEQEDEGVPSTA----IREISLLK 56
Query: 566 -MDHPNIIKIFDFYRDEKYFCVTMEYMDQKSVRCYLDKNNNRPLPEPLIKQFSLQVLDGL 742
M+H NI+++ D EK + EY+D ++ ++D LIK + Q+L G+
Sbjct: 57 EMNHGNIVRLHDVVHSEKRIYLVFEYLD-LDLKKFMDSCPEFAKNPTLIKSYLYQILHGV 115
Query: 743 VFMHS 757
+ HS
Sbjct: 116 AYCHS 120
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 94,025,825
Number of Sequences: 369166
Number of extensions: 1999477
Number of successful extensions: 6044
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5540
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5860
length of database: 68,354,980
effective HSP length: 108
effective length of database: 48,403,600
effective search space used: 7454154400
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)