Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_007_H22
(463 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q90839|DKK3_CHICK Dickkopf-related protein 3 precursor (... 32 0.53
sp|O54890|ITB3_MOUSE Integrin beta-3 precursor (Platelet me... 32 0.69
sp|P05106|ITB3_HUMAN Integrin beta-3 precursor (Platelet me... 32 0.90
sp|Q9UBP4|DKK3_HUMAN Dickkopf-related protein 3 precursor (... 32 0.90
sp|P53813|PROS_RAT Vitamin K-dependent protein S precursor 31 1.5
sp|P98118|PROS_RABIT Vitamin K-dependent protein S precursor 31 1.5
sp|P97776|ADA18_RAT ADAM 18 (A disintegrin and metalloprote... 31 1.5
sp|Q9Y219|JAG2_HUMAN Jagged-2 precursor (Jagged2) (HJ2) 30 2.0
sp|Q9QUN9|DKK3_MOUSE Dickkopf-related protein 3 precursor (... 30 2.6
sp|P24787|NEUV_CHICK Vasotocin-neurophysin VT precursor [Co... 30 2.6
>sp|Q90839|DKK3_CHICK Dickkopf-related protein 3 precursor (Dkk-3) (Dickkopf-3) (Lens
fiber protein CLFEST4)
Length = 350
Score = 32.3 bits (72), Expect = 0.53
Identities = 14/56 (25%), Positives = 25/56 (44%)
Frame = +3
Query: 114 CEFENGFCFAHDQCCGNLMCKIVNDFGQCSTVNLNEIHKAGVPCRSHNDCGANMCC 281
C+ ++ C +CCG+ +C +G+C + G C + +DC CC
Sbjct: 163 CKTQHTHCSRDVECCGDQLCV----WGECRKATSRG--ENGTICENQHDCNPGTCC 212
>sp|O54890|ITB3_MOUSE Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa)
(GPIIIa) (CD61 antigen)
Length = 787
Score = 32.0 bits (71), Expect = 0.69
Identities = 24/95 (25%), Positives = 40/95 (42%), Gaps = 5/95 (5%)
Frame = +3
Query: 120 FENGFCFAHDQC-CGNLMCKI--VNDFGQCSTVNLNEIHKAGVPC--RSHNDCGANMCCF 284
++ C H QC CG+ +C + C+T + G+ C R + +CG+ +C
Sbjct: 556 YKGEMCSGHGQCNCGDCVCDSDWTGYYCNCTTRTDTCMSTNGLLCSGRGNCECGSCVCVQ 615
Query: 285 SDTYGTGQREIRTCHNAIGQTCESHTKIKNDKMFN 389
+YG + TC +A C + K FN
Sbjct: 616 PGSYGDTCEKCPTCPDA----CSFKKECVECKKFN 646
>sp|P05106|ITB3_HUMAN Integrin beta-3 precursor (Platelet membrane glycoprotein IIIa)
(GPIIIa) (CD61 antigen)
Length = 788
Score = 31.6 bits (70), Expect = 0.90
Identities = 20/77 (25%), Positives = 34/77 (44%), Gaps = 5/77 (6%)
Frame = +3
Query: 120 FENGFCFAHDQC-CGNLMCKI--VNDFGQCSTVNLNEIHKAGVPC--RSHNDCGANMCCF 284
++ C H QC CG+ +C + C+T + G+ C R +CG+ +C
Sbjct: 557 YKGEMCSGHGQCSCGDCLCDSDWTGYYCNCTTRTDTCMSSNGLLCSGRGKCECGSCVCIQ 616
Query: 285 SDTYGTGQREIRTCHNA 335
+YG + TC +A
Sbjct: 617 PGSYGDTCEKCPTCPDA 633
>sp|Q9UBP4|DKK3_HUMAN Dickkopf-related protein 3 precursor (Dkk-3) (Dickkopf-3) (hDkk-3)
Length = 350
Score = 31.6 bits (70), Expect = 0.90
Identities = 14/56 (25%), Positives = 24/56 (42%)
Frame = +3
Query: 114 CEFENGFCFAHDQCCGNLMCKIVNDFGQCSTVNLNEIHKAGVPCRSHNDCGANMCC 281
C + C +CCG+ +C +G C+ + + G C + DC +CC
Sbjct: 171 CRGQRMLCTRDSECCGDQLCV----WGHCTKMATRGSN--GTICDNQRDCQPGLCC 220
>sp|P53813|PROS_RAT Vitamin K-dependent protein S precursor
Length = 675
Score = 30.8 bits (68), Expect = 1.5
Identities = 15/72 (20%), Positives = 29/72 (40%)
Frame = +3
Query: 63 FKCQHELAKLVLENEAKCEFENGFCFAHDQCCGNLMCKIVNDFGQCSTVNLNEIHKAGVP 242
+ C ++ +L N+ C+ + C CG +CK + +C N +
Sbjct: 182 YHCSCKIGFAMLTNKKDCK-DVDECSLKPSVCGTAVCKNIPGDFECECPNGYRYDPSSKS 240
Query: 243 CRSHNDCGANMC 278
C+ ++C N C
Sbjct: 241 CKDVDECSENTC 252
>sp|P98118|PROS_RABIT Vitamin K-dependent protein S precursor
Length = 646
Score = 30.8 bits (68), Expect = 1.5
Identities = 16/72 (22%), Positives = 27/72 (37%)
Frame = +3
Query: 63 FKCQHELAKLVLENEAKCEFENGFCFAHDQCCGNLMCKIVNDFGQCSTVNLNEIHKAGVP 242
+ C + ++L NE C+ + C CG +CK +C +
Sbjct: 153 YHCSCKSGFVMLANEKDCK-DMDECSVKPSVCGTAVCKNTPGDFECECSEGYRYNPTAKS 211
Query: 243 CRSHNDCGANMC 278
C ++C NMC
Sbjct: 212 CEDIDECSENMC 223
>sp|P97776|ADA18_RAT ADAM 18 (A disintegrin and metalloproteinase domain 18)
(Transmembrane metalloproteinase-like, disintegrin-like,
and cysteine-rich protein III) (tMDC III)
Length = 445
Score = 30.8 bits (68), Expect = 1.5
Identities = 23/78 (29%), Positives = 33/78 (42%), Gaps = 13/78 (16%)
Frame = +3
Query: 102 NEAKCEFENGFCFAHDQCCGNLMCKIVND----FGQCSTVNLNEIHKAGVPCRSHND--C 263
NE +C+F+ +CC + CK+ G C T E+ AG PCR D C
Sbjct: 131 NETECQFK--------ECCNHETCKLKGSAQCGSGTCCTPKC-ELSAAGTPCRKAVDPEC 181
Query: 264 -------GANMCCFSDTY 296
G++ C DT+
Sbjct: 182 DFTEYCDGSSSHCVPDTF 199
>sp|Q9Y219|JAG2_HUMAN Jagged-2 precursor (Jagged2) (HJ2)
Length = 1238
Score = 30.4 bits (67), Expect = 2.0
Identities = 25/108 (23%), Positives = 41/108 (37%), Gaps = 8/108 (7%)
Frame = +3
Query: 57 NGFKCQHELAKLVLENEAKCEFENGF----CFAHDQCCGNLMCKIVNDFGQCSTVNLNEI 224
NG +C + LE + C + F C + C C++++ G + +
Sbjct: 547 NGARCYN------LEGDYYCACPDDFGGKNCSVprePCPGGACRVIDGCGSDAGPGMPGT 600
Query: 225 HKAGVPCRSHNDC----GANMCCFSDTYGTGQREIRTCHNAIGQTCES 356
+GV C H C G N C D+ TG + +GQ C +
Sbjct: 601 AASGV-CGPHGRCVSQPGGNFSCICDSGFTGTYCHENIDDCLGQPCRN 647
>sp|Q9QUN9|DKK3_MOUSE Dickkopf-related protein 3 precursor (Dkk-3) (Dickkopf-3) (mDkk-3)
Length = 349
Score = 30.0 bits (66), Expect = 2.6
Identities = 14/56 (25%), Positives = 23/56 (41%)
Frame = +3
Query: 114 CEFENGFCFAHDQCCGNLMCKIVNDFGQCSTVNLNEIHKAGVPCRSHNDCGANMCC 281
C + C +CCG+ +C +G C+ + G C + DC +CC
Sbjct: 171 CRDQQMLCTRDSECCGDQLCA----WGHCTQKATKGGN--GTICDNQRDCQPGLCC 220
>sp|P24787|NEUV_CHICK Vasotocin-neurophysin VT precursor [Contains: Vasotocin (VT);
Neurophysin VT]
Length = 161
Score = 30.0 bits (66), Expect = 2.6
Identities = 20/60 (33%), Positives = 28/60 (46%), Gaps = 5/60 (8%)
Frame = +3
Query: 129 GFCFAHDQCCG-NLMCKI-VNDFGQCSTVNL--NEIHKAGVPCRSHNDCGAN-MCCFSDT 293
G CF CCG L C + + +C+ + + G PC S C AN +CC +DT
Sbjct: 50 GRCFGPGICCGAELGCYLGTAETRRCAEEDYMPSPCQAGGQPCGSDGRCAANGVCCSADT 109
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 52,013,946
Number of Sequences: 369166
Number of extensions: 1050396
Number of successful extensions: 2986
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2878
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2984
length of database: 68,354,980
effective HSP length: 101
effective length of database: 49,696,745
effective search space used: 2584230740
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)