Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= Dr_sW_007_H11 (616 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|Q75C43|SNX4_ASHGO Sorting nexin-4 (Autophagy-related pro... 37 0.052 sp|P07271|PIF1_YEAST DNA repair and recombination protein P... 33 0.44 sp|Q6CTQ0|SNX4_KLULA Sorting nexin-4 (Autophagy-related pro... 33 0.58 sp|Q4R5U9|SXN7_MACFA Sorting nexin-7 33 0.76 sp|Q9UNH6|SNX7_HUMAN Sorting nexin-7 32 0.99 sp|P12844|MYO3_CAEEL Myosin-3 (Myosin heavy chain A) (MHC A) 32 0.99 sp|Q7N365|YS56_PHOLL Hypothetical UPF0324 membrane protein ... 32 0.99 sp|P40007|YEJ2_YEAST Hypothetical 26.9 kDa protein in MNN1-... 32 0.99 sp|P47057|SNX4_YEAST Sorting nexin-4 (Autophagy-related pro... 32 1.3 sp|Q9CY18|SNX7_MOUSE Sorting nexin-7 31 2.2
>sp|Q75C43|SNX4_ASHGO Sorting nexin-4 (Autophagy-related protein 24) Length = 410 Score = 36.6 bits (83), Expect = 0.052 Identities = 25/99 (25%), Positives = 47/99 (47%) Frame = +1 Query: 88 WTQVQQVARRRNDAEAKFIASIVKQSKIQDQNEDISNQAEQGQVANKLHDIVSKNNADLI 267 +T + Q A RR K SK++ + + ++ + E A K+ D K + + Sbjct: 325 FTGINQEAARRE-----------KISKLESKVQALTTEVEN---AKKVADAFEK---EAL 367 Query: 268 SEIDRWKEQRCEETKEWLKVFADLHIDHYRQMSTIWRKV 384 E++ +++ + E K L AD HI+ Y++M W K+ Sbjct: 368 KEVEIFEQIKTRELKRSLTTLADHHIEFYQKMVNTWSKI 406
>sp|P07271|PIF1_YEAST DNA repair and recombination protein PIF1, mitochondrial precursor (ATP-dependent helicase PIF1) Length = 857 Score = 33.5 bits (75), Expect = 0.44 Identities = 20/53 (37%), Positives = 29/53 (54%), Gaps = 3/53 (5%) Frame = +1 Query: 193 SNQAEQGQVANKLHDIVSKNNADLISEIDRWKEQRC---EETKEWLKVFADLH 342 SN Q Q+ K I+SK + DL+S+ D W+E C E K+ K+ D+H Sbjct: 47 SNNFIQAQL--KHPSILSKEDLDLLSDSDDWEEPDCIQLETEKQEKKIITDIH 97
>sp|Q6CTQ0|SNX4_KLULA Sorting nexin-4 (Autophagy-related protein 24) Length = 400 Score = 33.1 bits (74), Expect = 0.58 Identities = 15/76 (19%), Positives = 40/76 (52%) Frame = +1 Query: 157 KQSKIQDQNEDISNQAEQGQVANKLHDIVSKNNADLISEIDRWKEQRCEETKEWLKVFAD 336 K +K++ + + ++++ E+ + + + +++ E++++++ + E K+ L A Sbjct: 324 KIAKLETRVQSLTDEVEKSK------QVADEFEKEVLKEVEQFEQIKTLELKDSLAALAQ 377 Query: 337 LHIDHYRQMSTIWRKV 384 HID Y M W K+ Sbjct: 378 KHIDFYDDMVEKWSKI 393
>sp|Q4R5U9|SXN7_MACFA Sorting nexin-7 Length = 387 Score = 32.7 bits (73), Expect = 0.76 Identities = 26/111 (23%), Positives = 46/111 (41%) Frame = +1 Query: 61 PWIVESSLYWTQVQQVARRRNDAEAKFIASIVKQSKIQDQNEDISNQAEQGQVANKLHDI 240 P + E LY + V +RR+ +A+ SK++ ++ + KL D Sbjct: 269 PVVREYVLYSEMLMGVMKRRDQIQAEL------DSKVEALTYKKTDTDLLPEEIGKLEDK 322 Query: 241 VSKNNADLISEIDRWKEQRCEETKEWLKVFADLHIDHYRQMSTIWRKVVMS 393 V N L ++ +RWK+ + K A+ +I +Y Q W + S Sbjct: 323 VECANNALKADWERWKQNMQNDIKLAFTDMAEENIHYYEQCLATWESFLTS 373
>sp|Q9UNH6|SNX7_HUMAN Sorting nexin-7 Length = 387 Score = 32.3 bits (72), Expect = 0.99 Identities = 26/111 (23%), Positives = 46/111 (41%) Frame = +1 Query: 61 PWIVESSLYWTQVQQVARRRNDAEAKFIASIVKQSKIQDQNEDISNQAEQGQVANKLHDI 240 P + E LY + V +RR+ +A+ SK++ ++ + KL D Sbjct: 269 PVVHEYVLYSEMLMGVMKRRDQIQAEL------DSKVEVLTYKKADTDLLPEEIGKLEDK 322 Query: 241 VSKNNADLISEIDRWKEQRCEETKEWLKVFADLHIDHYRQMSTIWRKVVMS 393 V N L ++ +RWK+ + K A+ +I +Y Q W + S Sbjct: 323 VECANNALKADWERWKQNMQNDIKLAFTDMAEENIHYYEQCLATWESFLTS 373
>sp|P12844|MYO3_CAEEL Myosin-3 (Myosin heavy chain A) (MHC A) Length = 1969 Score = 32.3 bits (72), Expect = 0.99 Identities = 19/86 (22%), Positives = 45/86 (52%), Gaps = 4/86 (4%) Frame = +1 Query: 94 QVQQVARRRNDAEAKFIASIVKQSKIQDQNEDISNQAEQGQVANKLHDI----VSKNNAD 261 Q+++ R++++ +F+AS + + +Q + ++++ QAE + A + + + + N D Sbjct: 1669 QIEEEQRQKDEIREQFLASEKRNAILQSEKDELAQQAEAAERARRNAEAECIELREQNND 1728 Query: 262 LISEIDRWKEQRCEETKEWLKVFADL 339 L + + QR + E L A+L Sbjct: 1729 LNAHVSALTGQRRKLEGELLAAHAEL 1754
Score = 29.6 bits (65), Expect = 6.4 Identities = 19/73 (26%), Positives = 36/73 (49%), Gaps = 5/73 (6%) Frame = +1 Query: 142 IASIVKQSKIQDQ-----NEDISNQAEQGQVANKLHDIVSKNNADLISEIDRWKEQRCEE 306 +A + K+ K Q++ NED+ ++ ++ K+ + + + +L IDR K R + Sbjct: 1002 VAKLNKEKKHQEESNRKLNEDLQSEEDKVNHLEKIRNKLEQQMDELEENIDREKRSRGDI 1061 Query: 307 TKEWLKVFADLHI 345 K KV DL + Sbjct: 1062 EKAKRKVEGDLKV 1074
>sp|Q7N365|YS56_PHOLL Hypothetical UPF0324 membrane protein plu2856 Length = 360 Score = 32.3 bits (72), Expect = 0.99 Identities = 13/52 (25%), Positives = 28/52 (53%) Frame = +2 Query: 2 HHHWEINTNNQLKIFNGKSNHGLLRVVSIGHKFSRLLDDATMLRQNLSLVLL 157 H+ W T IF G + H + +VV++GH S ++ ++ + + +++L Sbjct: 194 HYQWLPLTQETFGIFTGSTLHEVAQVVAVGHAISDQTENVAVISKMIRVMML 245
>sp|P40007|YEJ2_YEAST Hypothetical 26.9 kDa protein in MNN1-PMI40 intergenic region Length = 231 Score = 32.3 bits (72), Expect = 0.99 Identities = 21/90 (23%), Positives = 41/90 (45%), Gaps = 5/90 (5%) Frame = +1 Query: 109 ARRRNDAEAKFIASIVKQSKIQDQNEDIS-----NQAEQGQVANKLHDIVSKNNADLISE 273 AR + D + + + K D +ED++ + E+ +V KL ++ S+ Sbjct: 117 ARIQRDKNGDVVRVVYGKKKNFDADEDVNEIKARDTTEETEVVKKLEELASR-------P 169 Query: 274 IDRWKEQRCEETKEWLKVFADLHIDHYRQM 363 + R + + E +EWL+ H D Y++M Sbjct: 170 VIRKERSQSEREEEWLEKLYKKHGDDYKKM 199
>sp|P47057|SNX4_YEAST Sorting nexin-4 (Autophagy-related protein 24) (Cytoplasm to vacuole targeting protein 13) Length = 423 Score = 32.0 bits (71), Expect = 1.3 Identities = 20/79 (25%), Positives = 35/79 (44%), Gaps = 14/79 (17%) Frame = +1 Query: 190 ISNQAEQGQVANKLHDIVSKNNADL--------------ISEIDRWKEQRCEETKEWLKV 327 I+ +A + + NKL ++ +L + EID ++ + E K+ L Sbjct: 341 INQEASRREKINKLEGKITSLTGELENAKKVADGFEQECLKEIDHFESVKTAEIKKSLGS 400 Query: 328 FADLHIDHYRQMSTIWRKV 384 AD HI+ Y ++ W KV Sbjct: 401 LADHHIEFYERILEAWEKV 419
>sp|Q9CY18|SNX7_MOUSE Sorting nexin-7 Length = 387 Score = 31.2 bits (69), Expect = 2.2 Identities = 28/115 (24%), Positives = 48/115 (41%), Gaps = 4/115 (3%) Frame = +1 Query: 61 PWIVESSLYWTQVQQVARRRN----DAEAKFIASIVKQSKIQDQNEDISNQAEQGQVANK 228 P + E LY + V +RR+ + ++K A K++ I E+I K Sbjct: 269 PVVHEYVLYSEMLVGVMKRRDQIQTELDSKVEALTYKKADIDLLTEEIG----------K 318 Query: 229 LHDIVSKNNADLISEIDRWKEQRCEETKEWLKVFADLHIDHYRQMSTIWRKVVMS 393 L D V N L ++ +RWK+ + + A+ +I +Y Q W + S Sbjct: 319 LEDKVECANNALKADWERWKQNMKNDLRSAFTDTAEQNIRYYEQCLATWESFLTS 373
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 64,284,158 Number of Sequences: 369166 Number of extensions: 1115097 Number of successful extensions: 3279 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 3204 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 3278 length of database: 68,354,980 effective HSP length: 105 effective length of database: 48,957,805 effective search space used: 4846822695 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)