Planarian EST Database


Dr_sW_007_H07

BLASTX 2.2.12 [Aug-07-2005]

Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= Dr_sW_007_H07
         (893 letters)

Database: Non-redundant SwissProt sequences 
           184,735 sequences; 68,354,980 total letters



                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

sp|P07154|CATL_RAT  Cathepsin L precursor (Major excreted pr...   303   3e-82
sp|P06797|CATL_MOUSE  Cathepsin L precursor (Major excreted ...   301   1e-81
sp|O60911|CATL2_HUMAN  Cathepsin L2 precursor (Cathepsin V) ...   300   4e-81
sp|P43236|CATK_RABIT  Cathepsin K precursor (OC-2 protein)        293   4e-79
sp|Q9GL24|CATL_CANFA  Cathepsin L precursor [Contains: Cathe...   292   8e-79
sp|P07711|CATL_HUMAN  Cathepsin L precursor (Major excreted ...   291   1e-78
sp|P25975|CATL_BOVIN  Cathepsin L precursor [Contains: Cathe...   291   2e-78
sp|P43235|CATK_HUMAN  Cathepsin K precursor (Cathepsin O) (C...   290   4e-78
sp|P61277|CATK_MACMU  Cathepsin K precursor >gi|47117667|sp|...   290   4e-78
sp|Q26636|CATL_SARPE  Cathepsin L precursor [Contains: Cathe...   289   6e-78
>sp|P07154|CATL_RAT Cathepsin L precursor (Major excreted protein) (MEP) (Cyclic
           protein 2) (CP-2) [Contains: Cathepsin L heavy chain;
           Cathepsin L light chain]
          Length = 334

 Score =  303 bits (777), Expect = 3e-82
 Identities = 161/302 (53%), Positives = 205/302 (67%), Gaps = 5/302 (1%)
 Frame = +2

Query: 2   TSVLLLFTILLRSSAFKFQINEELNDEWNLYKTRYQKSYLSIVELTRRIIWEENLRYIQH 181
           T +LLL  + L ++    + ++  N +W+ +K+ +++ Y +  E  RR +WE+N+R IQ 
Sbjct: 2   TPLLLLAVLCLGTALATPKFDQTFNAQWHQWKSTHRRLYGTNEEEWRRAVWEKNMRMIQL 61

Query: 182 HNLEYDLGKHSYYLGVNEYADLTHEEFKIKFLGLKPINRNYSRTIFMPPENMDNYPKSVD 361
           HN EY  GKH + + +N + D+T+EEF+    G +       R +F  P  M   PK+VD
Sbjct: 62  HNGEYSNGKHGFTMEMNAFGDMTNEEFRQIVNGYRHQKHKKGR-LFQEPL-MLQIPKTVD 119

Query: 362 WRKKGYVTPVKNQGQCGSCWSFSTTGALEGQHFRKRKQLVSLSEQQLVDCSKDYQNNGCN 541
           WR+KG VTPVKNQGQCGSCW+FS +G LEGQ F K  +L+SLSEQ LVDCS D  N GCN
Sbjct: 120 WREKGCVTPVKNQGQCGSCWAFSASGCLEGQMFLKTGKLISLSEQNLVDCSHDQGNQGCN 179

Query: 542 GGLMDNAFQYIQKY-GLESEADYPYTAMDGPCKYDSTKVVAHCTGFVDIKKGNEKDLTKA 718
           GGLMD AFQYI++  GL+SE  YPY A DG CKY +   VA+ TGFVDI +  EK L KA
Sbjct: 180 GGLMDFAFQYIKENGGLDSEESYPYEAKDGSCKYRAEYAVANDTGFVDIPQ-QEKALMKA 238

Query: 719 VATVGPISVAIDASRPSFQLYKGGIYNEVNCSSNNLDHGVLAVGYGAEG----KNHFWIV 886
           VATVGPISVA+DAS PS Q Y  GIY E NCSS +LDHGVL VGYG EG    K+ +W+V
Sbjct: 239 VATVGPISVAMDASHPSLQFYSSGIYYEPNCSSKDLDHGVLVVGYGYEGTDSNKDKYWLV 298

Query: 887 KN 892
           KN
Sbjct: 299 KN 300
>sp|P06797|CATL_MOUSE Cathepsin L precursor (Major excreted protein) (MEP) (p39 cysteine
           proteinase) [Contains: Cathepsin L heavy chain;
           Cathepsin L light chain]
          Length = 334

 Score =  301 bits (772), Expect = 1e-81
 Identities = 162/300 (54%), Positives = 203/300 (67%), Gaps = 5/300 (1%)
 Frame = +2

Query: 8   VLLLFTILLRSSAFKFQINEELNDEWNLYKTRYQKSYLSIVELTRRIIWEENLRYIQHHN 187
           +LLL  + L ++    + ++  + EW+ +K+ +++ Y +  E  RR IWE+N+R IQ HN
Sbjct: 4   LLLLAVLCLGTALATPKFDQTFSAEWHQWKSTHRRLYGTNEEEWRRAIWEKNMRMIQLHN 63

Query: 188 LEYDLGKHSYYLGVNEYADLTHEEFKIKFLGLKPINRNYSRTIFMPPENMDNYPKSVDWR 367
            EY  G+H + + +N + D+T+EEF+    G +       R +F  P  M   PKSVDWR
Sbjct: 64  GEYSNGQHGFSMEMNAFGDMTNEEFRQVVNGYRHQKHKKGR-LFQEPL-MLKIPKSVDWR 121

Query: 368 KKGYVTPVKNQGQCGSCWSFSTTGALEGQHFRKRKQLVSLSEQQLVDCSKDYQNNGCNGG 547
           +KG VTPVKNQGQCGSCW+FS +G LEGQ F K  +L+SLSEQ LVDCS    N GCNGG
Sbjct: 122 EKGCVTPVKNQGQCGSCWAFSASGCLEGQMFLKTGKLISLSEQNLVDCSHAQGNQGCNGG 181

Query: 548 LMDNAFQYIQKY-GLESEADYPYTAMDGPCKYDSTKVVAHCTGFVDIKKGNEKDLTKAVA 724
           LMD AFQYI++  GL+SE  YPY A DG CKY +   VA+ TGFVDI +  EK L KAVA
Sbjct: 182 LMDFAFQYIKENGGLDSEESYPYEAKDGSCKYRAEFAVANDTGFVDIPQ-QEKALMKAVA 240

Query: 725 TVGPISVAIDASRPSFQLYKGGIYNEVNCSSNNLDHGVLAVGYGAEG----KNHFWIVKN 892
           TVGPISVA+DAS PS Q Y  GIY E NCSS NLDHGVL VGYG EG    KN +W+VKN
Sbjct: 241 TVGPISVAMDASHPSLQFYSSGIYYEPNCSSKNLDHGVLLVGYGYEGTDSNKNKYWLVKN 300
>sp|O60911|CATL2_HUMAN Cathepsin L2 precursor (Cathepsin V) (Cathepsin U)
          Length = 334

 Score =  300 bits (768), Expect = 4e-81
 Identities = 159/300 (53%), Positives = 200/300 (66%), Gaps = 5/300 (1%)
 Frame = +2

Query: 8   VLLLFTILLRSSAFKFQINEELNDEWNLYKTRYQKSYLSIVELTRRIIWEENLRYIQHHN 187
           VL  F + + S+  KF  N  L+ +W  +K  +++ Y +  E  RR +WE+N++ I+ HN
Sbjct: 6   VLAAFCLGIASAVPKFDQN--LDTKWYQWKATHRRLYGANEEGWRRAVWEKNMKMIELHN 63

Query: 188 LEYDLGKHSYYLGVNEYADLTHEEFKIKFLGLKPINRNYSRTIFMPPENMDNYPKSVDWR 367
            EY  GKH + + +N + D+T+EEF+ + +G     +     +F  P  +D  PKSVDWR
Sbjct: 64  GEYSQGKHGFTMAMNAFGDMTNEEFR-QMMGCFRNQKFRKGKVFREPLFLD-LPKSVDWR 121

Query: 368 KKGYVTPVKNQGQCGSCWSFSTTGALEGQHFRKRKQLVSLSEQQLVDCSKDYQNNGCNGG 547
           KKGYVTPVKNQ QCGSCW+FS TGALEGQ FRK  +LVSLSEQ LVDCS+   N GCNGG
Sbjct: 122 KKGYVTPVKNQKQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQGNQGCNGG 181

Query: 548 LMDNAFQYIQKY-GLESEADYPYTAMDGPCKYDSTKVVAHCTGFVDIKKGNEKDLTKAVA 724
            M  AFQY+++  GL+SE  YPY A+D  CKY     VA+ TGF  +  G EK L KAVA
Sbjct: 182 FMARAFQYVKENGGLDSEESYPYVAVDEICKYRPENSVANDTGFTVVAPGKEKALMKAVA 241

Query: 725 TVGPISVAIDASRPSFQLYKGGIYNEVNCSSNNLDHGVLAVGYGAEGKN----HFWIVKN 892
           TVGPISVA+DA   SFQ YK GIY E +CSS NLDHGVL VGYG EG N     +W+VKN
Sbjct: 242 TVGPISVAMDAGHSSFQFYKSGIYFEPDCSSKNLDHGVLVVGYGFEGANSNNSKYWLVKN 301
>sp|P43236|CATK_RABIT Cathepsin K precursor (OC-2 protein)
          Length = 329

 Score =  293 bits (750), Expect = 4e-79
 Identities = 152/295 (51%), Positives = 196/295 (66%), Gaps = 3/295 (1%)
 Frame = +2

Query: 17  LFTILLRSSAFKFQINEELNDEWNLYKTRYQKSYLSIV-ELTRRIIWEENLRYIQHHNLE 193
           L  +LL   +F     E L+ +W L+K  Y K Y S V E++RR+IWE+NL++I  HNLE
Sbjct: 4   LKVLLLPVVSFALHPEEILDTQWELWKKTYSKQYNSKVDEISRRLIWEKNLKHISIHNLE 63

Query: 194 YDLGKHSYYLGVNEYADLTHEEFKIKFLGLK-PINRNYSRTIFMPPENMDNYPKSVDWRK 370
             LG H+Y L +N   D+T EE   K  GLK P +R++S      P+     P S+D+RK
Sbjct: 64  ASLGVHTYELAMNHLGDMTSEEVVQKMTGLKVPPSRSHSNDTLYIPDWEGRTPDSIDYRK 123

Query: 371 KGYVTPVKNQGQCGSCWSFSTTGALEGQHFRKRKQLVSLSEQQLVDCSKDYQNNGCNGGL 550
           KGYVTPVKNQGQCGSCW+FS+ GALEGQ  +K  +L++LS Q LVDC  +  N GC GG 
Sbjct: 124 KGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSE--NYGCGGGY 181

Query: 551 MDNAFQYIQKY-GLESEADYPYTAMDGPCKYDSTKVVAHCTGFVDIKKGNEKDLTKAVAT 727
           M NAFQY+Q+  G++SE  YPY   D  C Y+ T   A C G+ +I +GNEK L +AVA 
Sbjct: 182 MTNAFQYVQRNRGIDSEDAYPYVGQDESCMYNPTGKAAKCRGYREIPEGNEKALKRAVAR 241

Query: 728 VGPISVAIDASRPSFQLYKGGIYNEVNCSSNNLDHGVLAVGYGAEGKNHFWIVKN 892
           VGP+SVAIDAS  SFQ Y  G+Y + NCSS+N++H VLAVGYG +  N  WI+KN
Sbjct: 242 VGPVSVAIDASLTSFQFYSKGVYYDENCSSDNVNHAVLAVGYGIQKGNKHWIIKN 296
>sp|Q9GL24|CATL_CANFA Cathepsin L precursor [Contains: Cathepsin L heavy chain; Cathepsin
           L light chain]
          Length = 333

 Score =  292 bits (748), Expect = 8e-79
 Identities = 155/292 (53%), Positives = 195/292 (66%), Gaps = 5/292 (1%)
 Frame = +2

Query: 32  LRSSAFKFQINEELNDEWNLYKTRYQKSYLSIVELTRRIIWEENLRYIQHHNLEYDLGKH 211
           + S+A KF  ++ LN +W  +K  +++ Y    E  RR +WE+N++ I+ HN EY  GKH
Sbjct: 14  IASAAPKF--DQSLNAQWYQWKATHRRLYGMNEEGWRRAVWEKNMKMIELHNREYSQGKH 71

Query: 212 SYYLGVNEYADLTHEEFKIKFLGLKPINRNYSRTIFMPPENMDNYPKSVDWRKKGYVTPV 391
            + + +N + D+T+EEF+    G +  N+ + +            PKSVDWR+KGYVTPV
Sbjct: 72  GFTMAMNAFGDMTNEEFRQVMNGFQ--NQKHKKGKMFQEPLFAEIPKSVDWREKGYVTPV 129

Query: 392 KNQGQCGSCWSFSTTGALEGQHFRKRKQLVSLSEQQLVDCSKDYQNNGCNGGLMDNAFQY 571
           KNQGQCGSCW+FS TGALEGQ FRK  +LVSLSEQ LVDCS+   N GCNGGLMDNAF+Y
Sbjct: 130 KNQGQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRAQGNEGCNGGLMDNAFRY 189

Query: 572 IQ-KYGLESEADYPYTAMD-GPCKYDSTKVVAHCTGFVDIKKGNEKDLTKAVATVGPISV 745
           ++   GL+SE  YPY   D   C Y      A+ TGFVD+ +  EK L KAVAT+GPISV
Sbjct: 190 VKDNGGLDSEESYPYLGRDTETCNYKPECSAANDTGFVDLPQ-REKALMKAVATLGPISV 248

Query: 746 AIDASRPSFQLYKGGIYNEVNCSSNNLDHGVLAVGYGAEG---KNHFWIVKN 892
           AIDA   SFQ YK GIY + +CSS +LDHGVL VGYG EG    N FWIVKN
Sbjct: 249 AIDAGHQSFQFYKSGIYFDPDCSSKDLDHGVLVVGYGFEGTDSNNKFWIVKN 300
>sp|P07711|CATL_HUMAN Cathepsin L precursor (Major excreted protein) (MEP) [Contains:
           Cathepsin L heavy chain; Cathepsin L light chain]
          Length = 333

 Score =  291 bits (746), Expect = 1e-78
 Identities = 157/302 (51%), Positives = 194/302 (64%), Gaps = 5/302 (1%)
 Frame = +2

Query: 2   TSVLLLFTILLRSSAFKFQINEELNDEWNLYKTRYQKSYLSIVELTRRIIWEENLRYIQH 181
           T +L  F + + S+   F  +  L  +W  +K  + + Y    E  RR +WE+N++ I+ 
Sbjct: 4   TLILAAFCLGIASATLTF--DHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIEL 61

Query: 182 HNLEYDLGKHSYYLGVNEYADLTHEEFKIKFLGLKPINRNYSRTIFMPPENMDNYPKSVD 361
           HN EY  GKHS+ + +N + D+T EEF+    G +  NR   +            P+SVD
Sbjct: 62  HNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQ--NRKPRKGKVFQEPLFYEAPRSVD 119

Query: 362 WRKKGYVTPVKNQGQCGSCWSFSTTGALEGQHFRKRKQLVSLSEQQLVDCSKDYQNNGCN 541
           WR+KGYVTPVKNQGQCGSCW+FS TGALEGQ FRK  +L+SLSEQ LVDCS    N GCN
Sbjct: 120 WREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCN 179

Query: 542 GGLMDNAFQYIQ-KYGLESEADYPYTAMDGPCKYDSTKVVAHCTGFVDIKKGNEKDLTKA 718
           GGLMD AFQY+Q   GL+SE  YPY A +  CKY+    VA+ TGFVDI K  EK L KA
Sbjct: 180 GGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPK-QEKALMKA 238

Query: 719 VATVGPISVAIDASRPSFQLYKGGIYNEVNCSSNNLDHGVLAVGYGAEG----KNHFWIV 886
           VATVGPISVAIDA   SF  YK GIY E +CSS ++DHGVL VGYG E      N +W+V
Sbjct: 239 VATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLV 298

Query: 887 KN 892
           KN
Sbjct: 299 KN 300
>sp|P25975|CATL_BOVIN Cathepsin L precursor [Contains: Cathepsin L heavy chain; Cathepsin
           L light chain]
          Length = 334

 Score =  291 bits (745), Expect = 2e-78
 Identities = 154/285 (54%), Positives = 190/285 (66%), Gaps = 6/285 (2%)
 Frame = +2

Query: 56  QINEELNDEWNLYKTRYQKSYLSIVELTRRIIWEENLRYIQHHNLEYDLGKHSYYLGVNE 235
           +++  L+  W+ +K  +++ Y    E  RR +WE+N + I  HN EY  GKH++ + +N 
Sbjct: 20  KLDPNLDAHWHQWKATHRRLYGMNEEEWRRAVWEKNKKIIDLHNQEYSEGKHAFRMAMNA 79

Query: 236 YADLTHEEFKIKFLGLKPINRNYSRTIFMPPENMDNYPKSVDWRKKGYVTPVKNQGQCGS 415
           + D+T+EEF+    G +  N+ + +        + + PKSVDW KKGYVTPVKNQGQCGS
Sbjct: 80  FGDMTNEEFRQVMNGFQ--NQKHKKGKLFHEPLLVDVPKSVDWTKKGYVTPVKNQGQCGS 137

Query: 416 CWSFSTTGALEGQHFRKRKQLVSLSEQQLVDCSKDYQNNGCNGGLMDNAFQYIQ-KYGLE 592
           CW+FS TGALEGQ FRK  +LVSLSEQ LVDCS+   N GCNGGLMDNAFQYI+   GL+
Sbjct: 138 CWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRAQGNQGCNGGLMDNAFQYIKDNGGLD 197

Query: 593 SEADYPYTAMD-GPCKYDSTKVVAHCTGFVDIKKGNEKDLTKAVATVGPISVAIDASRPS 769
           SE  YPY A D   C Y      A+ TGFVDI +  EK L KAVATVGPISVAIDA   S
Sbjct: 198 SEESYPYLATDTNSCNYKPECSAANDTGFVDIPQ-REKALMKAVATVGPISVAIDAGHTS 256

Query: 770 FQLYKGGIYNEVNCSSNNLDHGVLAVGYGAEG----KNHFWIVKN 892
           FQ YK GIY + +CS  +LDHGVL VGYG EG     N FWIVKN
Sbjct: 257 FQFYKSGIYYDPDCSCKDLDHGVLVVGYGFEGTDSNNNKFWIVKN 301
>sp|P43235|CATK_HUMAN Cathepsin K precursor (Cathepsin O) (Cathepsin X) (Cathepsin O2)
          Length = 329

 Score =  290 bits (742), Expect = 4e-78
 Identities = 151/295 (51%), Positives = 196/295 (66%), Gaps = 3/295 (1%)
 Frame = +2

Query: 17  LFTILLRSSAFKFQINEELNDEWNLYKTRYQKSYLSIV-ELTRRIIWEENLRYIQHHNLE 193
           L  +LL   +F     E L+  W L+K  ++K Y + V E++RR+IWE+NL+YI  HNLE
Sbjct: 4   LKVLLLPVVSFALYPEEILDTHWELWKKTHRKQYNNKVDEISRRLIWEKNLKYISIHNLE 63

Query: 194 YDLGKHSYYLGVNEYADLTHEEFKIKFLGLK-PINRNYSRTIFMPPENMDNYPKSVDWRK 370
             LG H+Y L +N   D+T EE   K  GLK P++ + S      PE     P SVD+RK
Sbjct: 64  ASLGVHTYELAMNHLGDMTSEEVVQKMTGLKVPLSHSRSNDTLYIPEWEGRAPDSVDYRK 123

Query: 371 KGYVTPVKNQGQCGSCWSFSTTGALEGQHFRKRKQLVSLSEQQLVDCSKDYQNNGCNGGL 550
           KGYVTPVKNQGQCGSCW+FS+ GALEGQ  +K  +L++LS Q LVDC  +  N+GC GG 
Sbjct: 124 KGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSE--NDGCGGGY 181

Query: 551 MDNAFQYIQKY-GLESEADYPYTAMDGPCKYDSTKVVAHCTGFVDIKKGNEKDLTKAVAT 727
           M NAFQY+QK  G++SE  YPY   +  C Y+ T   A C G+ +I +GNEK L +AVA 
Sbjct: 182 MTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKALKRAVAR 241

Query: 728 VGPISVAIDASRPSFQLYKGGIYNEVNCSSNNLDHGVLAVGYGAEGKNHFWIVKN 892
           VGP+SVAIDAS  SFQ Y  G+Y + +C+S+NL+H VLAVGYG +  N  WI+KN
Sbjct: 242 VGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIKN 296
>sp|P61277|CATK_MACMU Cathepsin K precursor
 sp|P61276|CATK_MACFA Cathepsin K precursor
          Length = 329

 Score =  290 bits (742), Expect = 4e-78
 Identities = 151/295 (51%), Positives = 196/295 (66%), Gaps = 3/295 (1%)
 Frame = +2

Query: 17  LFTILLRSSAFKFQINEELNDEWNLYKTRYQKSYLSIV-ELTRRIIWEENLRYIQHHNLE 193
           L  +LL   +F     E L+  W L+K  ++K Y S V E++RR+IWE+NL+YI  HNLE
Sbjct: 4   LKVLLLPVMSFALYPEEILDTHWELWKKTHRKQYNSKVDEISRRLIWEKNLKYISIHNLE 63

Query: 194 YDLGKHSYYLGVNEYADLTHEEFKIKFLGLK-PINRNYSRTIFMPPENMDNYPKSVDWRK 370
             LG H+Y L +N   D+T+EE   K  GLK P + + S      P+     P SVD+RK
Sbjct: 64  ASLGVHTYELAMNHLGDMTNEEVVQKMTGLKVPASHSRSNDTLYIPDWEGRAPDSVDYRK 123

Query: 371 KGYVTPVKNQGQCGSCWSFSTTGALEGQHFRKRKQLVSLSEQQLVDCSKDYQNNGCNGGL 550
           KGYVTPVKNQGQCGSCW+FS+ GALEGQ  +K  +L++LS Q LVDC  +  N+GC GG 
Sbjct: 124 KGYVTPVKNQGQCGSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSE--NDGCGGGY 181

Query: 551 MDNAFQYIQKY-GLESEADYPYTAMDGPCKYDSTKVVAHCTGFVDIKKGNEKDLTKAVAT 727
           M NAFQY+QK  G++SE  YPY   +  C Y+ T   A C G+ +I +GNEK L +AVA 
Sbjct: 182 MTNAFQYVQKNRGIDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKALKRAVAR 241

Query: 728 VGPISVAIDASRPSFQLYKGGIYNEVNCSSNNLDHGVLAVGYGAEGKNHFWIVKN 892
           VGP+SVAIDAS  SFQ Y  G+Y + +C+S+NL+H VLAVGYG +  N  WI+KN
Sbjct: 242 VGPVSVAIDASLTSFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGNKHWIIKN 296
>sp|Q26636|CATL_SARPE Cathepsin L precursor [Contains: Cathepsin L heavy chain; Cathepsin
           L light chain]
          Length = 339

 Score =  289 bits (740), Expect = 6e-78
 Identities = 150/284 (52%), Positives = 190/284 (66%), Gaps = 10/284 (3%)
 Frame = +2

Query: 71  LNDEWNLYKTRYQKSYLSIVELTRRI-IWEENLRYIQHHNLEYDLGKHSYYLGVNEYADL 247
           + +EW+ YK +++K+Y + VE   R+ I+ EN   I  HN  +  GK SY LG+N+YAD+
Sbjct: 24  IKEEWHTYKLQHRKNYANEVEERFRMKIFNENRHKIAKHNQLFAQGKVSYKLGLNKYADM 83

Query: 248 THEEFKIKFLGLKPINRNYSR-------TIFMPPENMDNYPKSVDWRKKGYVTPVKNQGQ 406
            H EFK    G     R   R         ++PP ++   PKSVDWR+ G VT VK+QG 
Sbjct: 84  LHHEFKETMNGYNHTLRQLMRERTGLVGATYIPPAHV-TVPKSVDWREHGAVTGVKDQGH 142

Query: 407 CGSCWSFSTTGALEGQHFRKRKQLVSLSEQQLVDCSKDYQNNGCNGGLMDNAFQYIQ-KY 583
           CGSCW+FS+TGALEGQHFRK   LVSLSEQ LVDCS  Y NNGCNGGLMDNAF+YI+   
Sbjct: 143 CGSCWAFSSTGALEGQHFRKAGVLVSLSEQNLVDCSTKYGNNGCNGGLMDNAFRYIKDNG 202

Query: 584 GLESEADYPYTAMDGPCKYDSTKVVAHCTGFVDIKKGNEKDLTKAVATVGPISVAIDASR 763
           G+++E  YPY  +D  C ++   + A  TGFVDI +G+E+ + KAVAT+GP+SVAIDAS 
Sbjct: 203 GIDTEKSYPYEGIDDSCHFNKATIGATDTGFVDIPEGDEEKMKKAVATMGPVSVAIDASH 262

Query: 764 PSFQLYKGGIYNEVNCSSNNLDHGVLAVGYGA-EGKNHFWIVKN 892
            SFQLY  G+YNE  C   NLDHGVL VGYG  E    +W+VKN
Sbjct: 263 ESFQLYSEGVYNEPECDEQNLDHGVLVVGYGTDESGMDYWLVKN 306
  Database: Non-redundant SwissProt sequences
    Posted date:  Dec 6, 2005  7:40 AM
  Number of letters in database: 68,354,980
  Number of sequences in database:  184,735
  
  Database: swissprot.01
    Posted date:  Dec 6, 2005  8:18 AM
  Number of letters in database: 66,202,850
  Number of sequences in database:  184,431
  
Lambda     K      H
   0.318    0.134    0.401 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 101,571,263
Number of Sequences: 369166
Number of extensions: 2084893
Number of successful extensions: 6366
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 5569
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 5796
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 8982382310
frameshift window, decay const: 40,  0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)