Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_007_E22
(632 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P31226|SAX_RANCA Saxiphilin precursor (SAX) 65 1e-10
sp|P81439|EQST_ACTEQ Equistatin 62 9e-10
sp|P01267|THYG_BOVIN Thyroglobulin precursor 61 3e-09
sp|P06882|THYG_RAT Thyroglobulin precursor 60 6e-09
sp|O08710|THYG_MOUSE Thyroglobulin precursor 59 8e-09
sp|P01266|THYG_HUMAN Thyroglobulin precursor 59 8e-09
sp|O88322|NID2_MOUSE Nidogen-2 precursor (NID-2) (Entactin-2) 52 1e-06
sp|Q14112|NID2_HUMAN Nidogen-2 precursor (NID-2) (Osteonido... 52 2e-06
sp|Q8BKV0|TICN3_MOUSE Testican-3 precursor (SPARC/osteonect... 49 1e-05
sp|Q9BQ16|TICN3_HUMAN Testican-3 precursor (SPARC/osteonect... 48 2e-05
>sp|P31226|SAX_RANCA Saxiphilin precursor (SAX)
Length = 844
Score = 65.1 bits (157), Expect = 1e-10
Identities = 48/156 (30%), Positives = 78/156 (50%), Gaps = 15/156 (9%)
Frame = +2
Query: 83 SGECQESSECGID-SICISNICSANPKNTPCLEKYSKSRSGGLLGAQIPKCDSNGDFSPV 259
SGE E+S+ + I+ S+N CL++ ++ + ++G IP+CD G++ P
Sbjct: 80 SGEVYEASKDPYNLKPIIAEPYSSNRDLQKCLKERQQALAKKMIGHYIPQCDEKGNYQPQ 139
Query: 260 QCIGS--QCYCVDRDGKNIENYGAPIGES-INC------KCARDQDDY--RKTKLLGKMF 406
QC GS C+CV+ G+ I P G++ C KC +++ K+LG+
Sbjct: 140 QCHGSTGHCWCVNAMGEKISGTNTPPGQTRATCERHELPKCLKERQVALGGDEKVLGRFV 199
Query: 407 -RCTESGNYDSVQCIGSV--CFCANEHGQAIEGKQT 505
+C E GNY+ Q GS +C N G+ I G +T
Sbjct: 200 PQCDEKGNYEPQQFHGSTGYSWCVNAIGEEIAGTKT 235
>sp|P81439|EQST_ACTEQ Equistatin
Length = 199
Score = 62.4 bits (150), Expect = 9e-10
Identities = 38/121 (31%), Positives = 60/121 (49%), Gaps = 14/121 (11%)
Frame = +2
Query: 176 EKYSKSRSGGLLGAQIPKCDSNGDFSPVQCIGS--QCYCVDRDGKNIENYGAPIGESINC 349
++ S + GL+GA +P+C G+F QC GS C+CVD DGK I G I S +
Sbjct: 6 QQLQASANSGLIGAYVPQCKETGEFEEKQCWGSTGYCWCVDEDGKEI--LGTKIRGSPD- 62
Query: 350 KCARDQDDYRKTKLLGKMF----------RCTESGNYDSVQCIGS--VCFCANEHGQAIE 493
C+R + +++ + C G++D VQC S C+C ++ G+ +E
Sbjct: 63 -CSRRKAALTLCQMMQAIIVNVPGWCGPPSCKADGSFDEVQCCASNGECYCVDKKGKELE 121
Query: 494 G 496
G
Sbjct: 122 G 122
Score = 58.9 bits (141), Expect = 1e-08
Identities = 36/100 (36%), Positives = 48/100 (48%), Gaps = 9/100 (9%)
Frame = +2
Query: 224 PKCDSNGDFSPVQCIGS--QCYCVDRDGKNIENY---GAPIGESINCKCARDQDDYRKTK 388
P C ++G F VQC S +CYCVD+ GK +E G P E C +
Sbjct: 90 PSCKADGSFDEVQCCASNGECYCVDKKGKELEGTRQKGRPSCERHLSPCEEARLQAHSNS 149
Query: 389 LLGKMF--RCTESGNYDSVQCIGSV--CFCANEHGQAIEG 496
L MF +C E G+Y+ VQC S C+C +E G + G
Sbjct: 150 LRVGMFVPQCLEDGSYNPVQCWPSTGYCWCVDEGGVKVPG 189
Score = 38.5 bits (88), Expect = 0.014
Identities = 19/52 (36%), Positives = 30/52 (57%), Gaps = 3/52 (5%)
Frame = +2
Query: 164 TPCLEKYSKSRSGGL-LGAQIPKCDSNGDFSPVQCIGS--QCYCVDRDGKNI 310
+PC E ++ S L +G +P+C +G ++PVQC S C+CVD G +
Sbjct: 136 SPCEEARLQAHSNSLRVGMFVPQCLEDGSYNPVQCWPSTGYCWCVDEGGVKV 187
>sp|P01267|THYG_BOVIN Thyroglobulin precursor
Length = 2769
Score = 60.8 bits (146), Expect = 3e-09
Identities = 31/103 (30%), Positives = 45/103 (43%), Gaps = 8/103 (7%)
Frame = +2
Query: 221 IPKCDSNGDFSPVQCIGSQCYCVDRDGKNIENYGAPIGESINCKCARDQDDYRKTKLLGK 400
+P C + G + VQC C+CVD G+ + G C ++ R LLG
Sbjct: 616 VPACTAEGSYEEVQCFAGDCWCVDAQGRELAGSRVRGGRP-RCPTECEKQRARMQSLLGS 674
Query: 401 --------MFRCTESGNYDSVQCIGSVCFCANEHGQAIEGKQT 505
+ CT GN+ VQC S C+C + GQ I G ++
Sbjct: 675 QPAGSSLFVPACTSKGNFLPVQCFNSECYCVDTEGQPIPGTRS 717
Score = 54.7 bits (130), Expect = 2e-07
Identities = 38/129 (29%), Positives = 55/129 (42%), Gaps = 23/129 (17%)
Frame = +2
Query: 134 SNICSANPKNTPCLEKYSKSRSGGLLGAQ-------IPKCDSNGDFSPVQCIGSQCYCVD 292
S + P+ EK ++R LLG+Q +P C S G+F PVQC S+CYCVD
Sbjct: 648 SRVRGGRPRCPTECEK-QRARMQSLLGSQPAGSSLFVPACTSKGNFLPVQCFNSECYCVD 706
Query: 293 RDGKNIENYGAPIGESINCKCARDQDDYR--------------KTKLLGKMF--RCTESG 424
+G+ I + +GE C R L ++ +C+ SG
Sbjct: 707 TEGQPIPGTRSALGEPKKCPSPCQLQAERAFLGTVRTLVSNPSTLPALSSIYIPQCSASG 766
Query: 425 NYDSVQCIG 451
+ VQC G
Sbjct: 767 QWSPVQCDG 775
Score = 52.0 bits (123), Expect = 1e-06
Identities = 30/102 (29%), Positives = 47/102 (46%), Gaps = 10/102 (9%)
Frame = +2
Query: 221 IPKCDSNGDFSPVQC--IGSQCYCVDRDGKNI---ENYGAPIGESINCKCARDQ---DDY 376
+P+C +G F VQC G+ C+CVD DG+ + G P C+ + Q Y
Sbjct: 49 VPQCAEDGSFQTVQCGKDGASCWCVDADGREVPGSRQPGRPAACLSFCQLQKQQILLSSY 108
Query: 377 RKTKLLGKMFRCTESGNYDSVQC--IGSVCFCANEHGQAIEG 496
+ + +C +SG+Y VQC C+C + G + G
Sbjct: 109 INSTATSYLPQCQDSGDYSPVQCDLRRRQCWCVDAEGMEVYG 150
Score = 43.1 bits (100), Expect = 6e-04
Identities = 39/125 (31%), Positives = 55/125 (44%), Gaps = 6/125 (4%)
Frame = +2
Query: 89 ECQESSECGIDSICISNICSANPKNTPCLEKYSKSRSGGLLGAQIPKCDSNGDFSPVQC- 265
E S + G + C+S C K L Y S + L P+C +GD+SPVQC
Sbjct: 79 EVPGSRQPGRPAACLS-FCQLQ-KQQILLSSYINSTATSYL----PQCQDSGDYSPVQCD 132
Query: 266 -IGSQCYCVDRDGKNIENYGAPIGESINCKCARDQDDYRKTKLLGKMFR----CTESGNY 430
QC+CVD +G +E YG + +C R + + L G R C+ G +
Sbjct: 133 LRRRQCWCVDAEG--MEVYGTR-QQGRPARCPRSCEIRNRRLLHGVGDRSPPQCSPDGAF 189
Query: 431 DSVQC 445
VQC
Sbjct: 190 RPVQC 194
Score = 34.3 bits (77), Expect = 0.27
Identities = 14/34 (41%), Positives = 22/34 (64%), Gaps = 2/34 (5%)
Frame = +2
Query: 215 AQIPKCDSNGDFSPVQCIGS--QCYCVDRDGKNI 310
A +P+CD+ G + PVQC + C+CVD G+ +
Sbjct: 1026 AYLPQCDAFGGWEPVQCHAATGHCWCVDGKGEYV 1059
Score = 31.6 bits (70), Expect = 1.8
Identities = 12/31 (38%), Positives = 18/31 (58%), Gaps = 1/31 (3%)
Frame = +2
Query: 221 IPKCDSNGDFSPVQC-IGSQCYCVDRDGKNI 310
+P C +G++ QC G C+CVD G+ I
Sbjct: 316 VPSCHPDGEYQAAQCQQGGPCWCVDSRGQEI 346
>sp|P06882|THYG_RAT Thyroglobulin precursor
Length = 2768
Score = 59.7 bits (143), Expect = 6e-09
Identities = 31/102 (30%), Positives = 46/102 (45%), Gaps = 7/102 (6%)
Frame = +2
Query: 221 IPKCDSNGDFSPVQCIGSQCYCVDRDGKNIENYGAPIGE---SINCKCARDQ-DDYRKTK 388
+P C + G + +QC +C+CV+ GK +E G C+ R Q + +
Sbjct: 617 VPSCTAEGSYEDIQCYAGECWCVNSQGKEVEGSRVSGGHPRCPTKCEKQRAQMQNLAGAQ 676
Query: 389 LLGKMF---RCTESGNYDSVQCIGSVCFCANEHGQAIEGKQT 505
G F CT G + VQC S C+C + GQ I G Q+
Sbjct: 677 PAGSSFFVPTCTSEGYFLPVQCFNSECYCVDAEGQVIPGTQS 718
Score = 53.9 bits (128), Expect = 3e-07
Identities = 44/154 (28%), Positives = 65/154 (42%), Gaps = 23/154 (14%)
Frame = +2
Query: 134 SNICSANPKNTPCLEKYSKSRSGGLLGAQ-------IPKCDSNGDFSPVQCIGSQCYCVD 292
S + +P+ EK +++ L GAQ +P C S G F PVQC S+CYCVD
Sbjct: 649 SRVSGGHPRCPTKCEK-QRAQMQNLAGAQPAGSSFFVPTCTSEGYFLPVQCFNSECYCVD 707
Query: 293 RDGKNIENYGAPIGESINC-KCARDQDDYRKTKLLGKMF---------------RCTESG 424
+G+ I + IGE C + Q + ++G + +C+ SG
Sbjct: 708 AEGQVIPGTQSTIGEPKLCPSVCQLQAEQAFLGVVGVLLSNSSMVPPISSVYIPQCSTSG 767
Query: 425 NYDSVQCIGSVCFCANEHGQAIEGKQTVSIGNSD 526
+ VQC G H Q E + + NSD
Sbjct: 768 QWMPVQCDG-------PHEQVFEWYERWNTQNSD 794
Score = 48.9 bits (115), Expect = 1e-05
Identities = 31/102 (30%), Positives = 47/102 (46%), Gaps = 10/102 (9%)
Frame = +2
Query: 221 IPKCDSNGDFSPVQC--IGSQCYCVDRDGKNI---ENYGAPIGESINCKCARDQ---DDY 376
+P+C +G F VQC G C+CVD DG + G P C+ + + Y
Sbjct: 50 VPQCSEDGSFQTVQCQNDGQSCWCVDSDGTEVPGSRQLGRPTACLSFCQLHKQRILLSSY 109
Query: 377 RKTKLLGKMFRCTESGNYDSVQC-IGSV-CFCANEHGQAIEG 496
+ + +C +SGNY VQC + V C+C + G + G
Sbjct: 110 INSTDALYLPQCQDSGNYAPVQCDLQQVQCWCVDTEGMEVYG 151
Score = 38.1 bits (87), Expect = 0.019
Identities = 35/125 (28%), Positives = 54/125 (43%), Gaps = 6/125 (4%)
Frame = +2
Query: 89 ECQESSECGIDSICISNICSANPKNTPCLEKYSKSRSGGLLGAQIPKCDSNGDFSPVQC- 265
E S + G + C+S C + K L Y S +P+C +G+++PVQC
Sbjct: 80 EVPGSRQLGRPTACLS-FCQLH-KQRILLSSYINSTDA----LYLPQCQDSGNYAPVQCD 133
Query: 266 -IGSQCYCVDRDGKNIENYGAPIGESINCKCARDQDDYRKTKLLG----KMFRCTESGNY 430
QC+CVD +G +E YG + +C R + + L G +C G +
Sbjct: 134 LQQVQCWCVDTEG--MEVYGTR-QQGRPTRCPRSCEIRSRRLLHGVGDKSPPQCDADGEF 190
Query: 431 DSVQC 445
VQC
Sbjct: 191 MPVQC 195
Score = 33.9 bits (76), Expect = 0.36
Identities = 28/106 (26%), Positives = 49/106 (46%), Gaps = 19/106 (17%)
Frame = +2
Query: 212 GAQIPKCDSNGDFSPVQCI--GSQCYCVDRDGKNIENYGAPIGES-------INCKCAR- 361
G +P+C++ G + PVQC QC+CVD G+ I G+ + S +C+ +R
Sbjct: 1026 GPYMPQCNTIGGWEPVQCHPGTGQCWCVDGWGELIP--GSLMARSSQMPQCPTSCELSRA 1083
Query: 362 -------DQDDYRKTKLLGKMFR--CTESGNYDSVQCIGSVCFCAN 472
Q +++ G +F C ++G Y Q G+ +C +
Sbjct: 1084 NGLISAWKQAGHQRNPGPGDLFTPVCLQTGEYVRQQTSGTGAWCVD 1129
Score = 32.0 bits (71), Expect = 1.4
Identities = 19/53 (35%), Positives = 25/53 (47%), Gaps = 4/53 (7%)
Frame = +2
Query: 221 IPKCDSNGDFSPVQC-IGSQCYCVDRDGKNI---ENYGAPIGESINCKCARDQ 367
IP C +G + VQC + C+CVD G I G P+ CA+DQ
Sbjct: 317 IPSCHRDGHYQTVQCQMERMCWCVDAQGIEIPGTRQQGQPL------FCAKDQ 363
>sp|O08710|THYG_MOUSE Thyroglobulin precursor
Length = 2766
Score = 59.3 bits (142), Expect = 8e-09
Identities = 31/102 (30%), Positives = 45/102 (44%), Gaps = 7/102 (6%)
Frame = +2
Query: 221 IPKCDSNGDFSPVQCIGSQCYCVDRDGKNIENYGAPIGE---SINCKCARDQ-DDYRKTK 388
+P C + G + +QC +C+CVD GK ++ G C+ R Q +
Sbjct: 617 VPSCTAGGSYEDIQCYAGECWCVDSRGKELDGSRVRGGRPRCPTKCEKQRAQMQSLASAQ 676
Query: 389 LLGKMF---RCTESGNYDSVQCIGSVCFCANEHGQAIEGKQT 505
G F CT G + VQC S C+C + GQ I G Q+
Sbjct: 677 PAGSSFFVPTCTREGYFLPVQCFNSECYCVDTEGQVIPGTQS 718
Score = 49.7 bits (117), Expect = 6e-06
Identities = 28/93 (30%), Positives = 43/93 (46%), Gaps = 16/93 (17%)
Frame = +2
Query: 221 IPKCDSNGDFSPVQCIGSQCYCVDRDGKNIENYGAPIGESINC-KCARDQDDYRKTKLLG 397
+P C G F PVQC S+CYCVD +G+ I + +GE+ C + Q + ++G
Sbjct: 684 VPTCTREGYFLPVQCFNSECYCVDTEGQVIPGTQSTVGEAKQCPSVCQLQAEQAFLGVVG 743
Query: 398 KMF---------------RCTESGNYDSVQCIG 451
+ +C+ SG + VQC G
Sbjct: 744 VLLSNSSMVPSISNVYIPQCSASGQWRHVQCDG 776
Score = 48.1 bits (113), Expect = 2e-05
Identities = 31/102 (30%), Positives = 48/102 (47%), Gaps = 10/102 (9%)
Frame = +2
Query: 221 IPKCDSNGDFSPVQCI--GSQCYCVDRDGKNI---ENYGAPIGESINCKCARDQ---DDY 376
+P+C +G F VQC G C+CVD DG+ + G P C+ + + Y
Sbjct: 50 VPQCSEDGSFQTVQCQNDGQSCWCVDSDGREVPGSRQLGRPTVCLSFCQLHKQRILLGSY 109
Query: 377 RKTKLLGKMFRCTESGNYDSVQC-IGSV-CFCANEHGQAIEG 496
+ + +C +SGNY VQC + V C+C + G + G
Sbjct: 110 INSTDALYLPQCQDSGNYAPVQCDLQRVQCWCVDTEGMEVYG 151
Score = 42.4 bits (98), Expect = 0.001
Identities = 37/125 (29%), Positives = 56/125 (44%), Gaps = 6/125 (4%)
Frame = +2
Query: 89 ECQESSECGIDSICISNICSANPKNTPCLEKYSKSRSGGLLGAQIPKCDSNGDFSPVQC- 265
E S + G ++C+S C + K L Y S +P+C +G+++PVQC
Sbjct: 80 EVPGSRQLGRPTVCLS-FCQLH-KQRILLGSYINSTDA----LYLPQCQDSGNYAPVQCD 133
Query: 266 -IGSQCYCVDRDGKNIENYGAPIGESINCKCARDQDDYRKTKLLGKMFR----CTESGNY 430
QC+CVD +G +E YG + +C R + + L G R CT G +
Sbjct: 134 LQRVQCWCVDTEG--MEVYGTR-QQGRPTRCPRSCEIRNRRLLHGVGDRSPPQCTADGEF 190
Query: 431 DSVQC 445
VQC
Sbjct: 191 MPVQC 195
Score = 34.7 bits (78), Expect = 0.21
Identities = 21/73 (28%), Positives = 37/73 (50%), Gaps = 5/73 (6%)
Frame = +2
Query: 164 TPC-LEKYSKSRSGGLLGAQIPKCDSNGDFSPVQC-IGSQCYCVDRDGKNI---ENYGAP 328
T C +E+++ +R G + IP+C +G + VQC C+CVD G+ + G P
Sbjct: 300 TKCEVEQFAATRFGH---SYIPRCHRDGHYQTVQCQTEGMCWCVDAQGREVPGTRQQGQP 356
Query: 329 IGESINCKCARDQ 367
+ + CA ++
Sbjct: 357 PSCAADQSCALER 369
Score = 33.5 bits (75), Expect = 0.46
Identities = 29/106 (27%), Positives = 47/106 (44%), Gaps = 19/106 (17%)
Frame = +2
Query: 212 GAQIPKCDSNGDFSPVQCIG--SQCYCVDRDGKNIENYGAPIGES-------INCKCAR- 361
G +P+C+ G + PVQC QC+CVD G+ I G+ + S NC+ +R
Sbjct: 1026 GPYMPQCNMIGGWEPVQCHAGTGQCWCVDGRGEFIP--GSLMSRSSQMPQCPTNCELSRA 1083
Query: 362 -------DQDDYRKTKLLGKMF--RCTESGNYDSVQCIGSVCFCAN 472
Q ++ G +F C ++G Y Q G+ +C +
Sbjct: 1084 SGLISAWKQAGPQRNPGPGDLFIPVCLQTGEYVRKQTSGTGTWCVD 1129
Score = 29.3 bits (64), Expect = 8.8
Identities = 11/31 (35%), Positives = 18/31 (58%), Gaps = 1/31 (3%)
Frame = +2
Query: 407 RCTESGNYDSVQC-IGSVCFCANEHGQAIEG 496
RC G+Y +VQC +C+C + G+ + G
Sbjct: 319 RCHRDGHYQTVQCQTEGMCWCVDAQGREVPG 349
>sp|P01266|THYG_HUMAN Thyroglobulin precursor
Length = 2768
Score = 59.3 bits (142), Expect = 8e-09
Identities = 30/103 (29%), Positives = 48/103 (46%), Gaps = 8/103 (7%)
Frame = +2
Query: 221 IPKCDSNGDFSPVQCIGSQCYCVDRDGKNIENYGAPIGESINCKCARDQDDYRKTKLLGK 400
+P C + G + VQC +C+CV+ GK + G+ C ++ R L+G
Sbjct: 617 VPSCTTEGSYEDVQCFSGECWCVNSWGKELPGSRVRGGQP-RCPTDCEKQRARMQSLMGS 675
Query: 401 --------MFRCTESGNYDSVQCIGSVCFCANEHGQAIEGKQT 505
+ CT G++ VQC S C+C + GQAI G ++
Sbjct: 676 QPAGSTLFVPACTSEGHFLPVQCFNSECYCVDAEGQAIPGTRS 718
Score = 53.5 bits (127), Expect = 4e-07
Identities = 33/96 (34%), Positives = 48/96 (50%), Gaps = 7/96 (7%)
Frame = +2
Query: 83 SGECQESSECGIDSICISNICSANPKNTPCLEKYSKSRSGGLLGAQ-------IPKCDSN 241
SGEC + G + + S + P+ EK ++R L+G+Q +P C S
Sbjct: 633 SGECWCVNSWGKE-LPGSRVRGGQPRCPTDCEK-QRARMQSLMGSQPAGSTLFVPACTSE 690
Query: 242 GDFSPVQCIGSQCYCVDRDGKNIENYGAPIGESINC 349
G F PVQC S+CYCVD +G+ I + IG+ C
Sbjct: 691 GHFLPVQCFNSECYCVDAEGQAIPGTRSAIGKPKKC 726
Score = 45.8 bits (107), Expect = 9e-05
Identities = 29/102 (28%), Positives = 47/102 (46%), Gaps = 10/102 (9%)
Frame = +2
Query: 221 IPKCDSNGDFSPVQC--IGSQCYCVDRDGKNI---ENYGAPIGESINCKCARDQ---DDY 376
+P+C +G F VQC G C+CV +G + G P+ C+ + Q Y
Sbjct: 49 VPQCAEDGSFQTVQCQNDGRSCWCVGANGSEVLGSRQPGRPVACLSFCQLQKQQILLSGY 108
Query: 377 RKTKLLGKMFRCTESGNYDSVQC-IGSV-CFCANEHGQAIEG 496
+ + +C +SG+Y VQC + V C+C + G + G
Sbjct: 109 INSTDTSYLPQCQDSGDYAPVQCDVQQVQCWCVDAEGMEVYG 150
Score = 42.0 bits (97), Expect = 0.001
Identities = 26/80 (32%), Positives = 42/80 (52%), Gaps = 5/80 (6%)
Frame = +2
Query: 221 IPKCDSNGDFSPVQCIGS--QCYCVDRDGKNIENYGA-PIGESINCKCARDQDDYRKTKL 391
+P+C +GD++PVQC QC+CVD +G +E YG +G C + + + R
Sbjct: 117 LPQCQDSGDYAPVQCDVQQVQCWCVDAEG--MEVYGTRQLGRPKRCPRSCEIRNRRLLHG 174
Query: 392 LGKMF--RCTESGNYDSVQC 445
+G +C+ G + VQC
Sbjct: 175 VGDKSPPQCSAEGEFMPVQC 194
Score = 37.0 bits (84), Expect = 0.042
Identities = 28/106 (26%), Positives = 44/106 (41%), Gaps = 19/106 (17%)
Frame = +2
Query: 212 GAQIPKCDSNGDFSPVQCIG--SQCYCVDRDGKNIENYGAPIGESINC-KCARDQDDYRK 382
G +P+CD+ G + PVQC C+CVD G I G+ S+ +C + R
Sbjct: 1025 GPYMPQCDAFGSWEPVQCHAGTGHCWCVDEKGGFIP--GSLTARSLQIPQCPTTCEKSRT 1082
Query: 383 TKLLGKMFR----------------CTESGNYDSVQCIGSVCFCAN 472
+ LL + C E+G Y +Q G+ +C +
Sbjct: 1083 SGLLSSWKQARSQENPSPKDLFVPACLETGEYARLQASGAGTWCVD 1128
Score = 35.8 bits (81), Expect = 0.094
Identities = 20/55 (36%), Positives = 25/55 (45%), Gaps = 6/55 (10%)
Frame = +2
Query: 221 IPKCDSNGDFSPVQC-IGSQCYCVDRDGKNI---ENYGAP--IGESINCKCARDQ 367
+P C NGD+ VQC C+CVD GK + G P E +C R Q
Sbjct: 316 VPSCRRNGDYQAVQCQTEGPCWCVDAQGKEMHGTRQQGEPPSCAEGQSCASERQQ 370
Score = 30.8 bits (68), Expect = 3.0
Identities = 19/50 (38%), Positives = 26/50 (52%), Gaps = 7/50 (14%)
Frame = +2
Query: 221 IPKCDS-NGDFSPVQCIGSQ--CYCVDRDGKNIENY----GAPIGESINC 349
+P C + +G FSPVQC +Q C+CV G+ + G P ES C
Sbjct: 1166 VPACRAEDGGFSPVQCDQAQGSCWCVMDSGEEVPGTRVTGGQPACESPRC 1215
>sp|O88322|NID2_MOUSE Nidogen-2 precursor (NID-2) (Entactin-2)
Length = 1403
Score = 52.0 bits (123), Expect = 1e-06
Identities = 31/118 (26%), Positives = 56/118 (47%), Gaps = 23/118 (19%)
Frame = +2
Query: 221 IPKCDSNGDFSPVQCIGSQ--CYCVDRDGKNIENYGAPIGESINCKCARDQDDYRKTKLL 394
IP+CD G+F P+QC GS C+CVDR+G + P G S C + ++ + +
Sbjct: 988 IPQCDDQGNFVPLQCHGSTGFCWCVDRNGHEVPGTQTPPG-STPPHCGPPPEPTQRPRTV 1046
Query: 395 GKMFR-------------------CTESGNYDSVQCIG--SVCFCANEHGQAIEGKQT 505
+ +R C + G++ +QC G C+C ++ G+ ++G ++
Sbjct: 1047 CERWRESLLEHYGGTPRDDQYVPQCDDLGHFIPLQCHGKSDFCWCVDKDGRELQGTRS 1104
Score = 41.2 bits (95), Expect = 0.002
Identities = 17/45 (37%), Positives = 26/45 (57%), Gaps = 2/45 (4%)
Frame = +2
Query: 221 IPKCDSNGDFSPVQCIGSQ--CYCVDRDGKNIENYGAPIGESINC 349
+P+CD G F P+QC G C+CVD+DG+ ++ + G C
Sbjct: 1068 VPQCDDLGHFIPLQCHGKSDFCWCVDKDGRELQGTRSQPGTRPAC 1112
>sp|Q14112|NID2_HUMAN Nidogen-2 precursor (NID-2) (Osteonidogen)
Length = 1375
Score = 51.6 bits (122), Expect = 2e-06
Identities = 36/140 (25%), Positives = 65/140 (46%), Gaps = 26/140 (18%)
Frame = +2
Query: 164 TPCLEKYSKSRSG-GLLGAQ--IPKCDSNGDFSPVQCIGSQ--CYCVDRDGKNIENYGAP 328
TPC ++ +++ GA+ IP+CD G+F P+QC GS C+CVD DG + P
Sbjct: 938 TPCEQQQRHAQAQYAYPGARFHIPQCDEQGNFLPLQCHGSTGFCWCVDPDGHEVPGTQTP 997
Query: 329 IGESINCKCARDQDDYRKTKLLGKMFR-------------------CTESGNYDSVQCIG 451
G S C + ++ + + +R C + G++ +QC G
Sbjct: 998 PG-STPPHCGPSPEPTQRPPTICERWRENLLEHYGGTPRDDQYVPQCDDLGHFIPLQCHG 1056
Query: 452 --SVCFCANEHGQAIEGKQT 505
C+C ++ G+ ++G ++
Sbjct: 1057 KSDFCWCVDKDGREVQGTRS 1076
Score = 42.4 bits (98), Expect = 0.001
Identities = 17/45 (37%), Positives = 27/45 (60%), Gaps = 2/45 (4%)
Frame = +2
Query: 221 IPKCDSNGDFSPVQCIGSQ--CYCVDRDGKNIENYGAPIGESINC 349
+P+CD G F P+QC G C+CVD+DG+ ++ + G + C
Sbjct: 1040 VPQCDDLGHFIPLQCHGKSDFCWCVDKDGREVQGTRSQPGTTPAC 1084
>sp|Q8BKV0|TICN3_MOUSE Testican-3 precursor (SPARC/osteonectin, CWCV, and Kazal-like
domains proteoglycan 3)
Length = 436
Score = 48.5 bits (114), Expect = 1e-05
Identities = 35/93 (37%), Positives = 46/93 (49%), Gaps = 11/93 (11%)
Frame = +2
Query: 119 DSICISN---ICSANPKNTPCLEKYS--KSRSG--GLLGAQIPKCDSNGDFSPVQCIGS- 274
DS+ +N C ++ PC + S + R G LLG IP CD +G + P QC GS
Sbjct: 297 DSLISNNEWCYCFQRQQDPPCHTELSNIQKRQGIKKLLGQYIPLCDEDGYYKPTQCHGSV 356
Query: 275 -QCYCVDRDGKNIENYGAPIGESIN--CKCARD 364
QC+CVDR G + +G IN CA D
Sbjct: 357 GQCWCVDRYGNEV------VGSRINGVADCAID 383
Score = 33.1 bits (74), Expect = 0.61
Identities = 17/42 (40%), Positives = 23/42 (54%), Gaps = 3/42 (7%)
Frame = +2
Query: 386 KLLGKMFR-CTESGNYDSVQCIGSV--CFCANEHGQAIEGKQ 502
KLLG+ C E G Y QC GSV C+C + +G + G +
Sbjct: 332 KLLGQYIPLCDEDGYYKPTQCHGSVGQCWCVDRYGNEVVGSR 373
>sp|Q9BQ16|TICN3_HUMAN Testican-3 precursor (SPARC/osteonectin, CWCV, and Kazal-like
domains proteoglycan 3)
Length = 436
Score = 48.1 bits (113), Expect = 2e-05
Identities = 35/93 (37%), Positives = 46/93 (49%), Gaps = 11/93 (11%)
Frame = +2
Query: 119 DSICISN---ICSANPKNTPCLEKYS--KSRSG--GLLGAQIPKCDSNGDFSPVQCIGS- 274
DS+ +N C ++ PC + S + R G LLG IP CD +G + P QC GS
Sbjct: 297 DSLISNNEWCYCFQRQQDPPCQTELSNIQKRQGVKKLLGQYIPLCDEDGYYKPTQCHGSV 356
Query: 275 -QCYCVDRDGKNIENYGAPIGESIN--CKCARD 364
QC+CVDR G + +G IN CA D
Sbjct: 357 GQCWCVDRYGNEV------MGSRINGVADCAID 383
Score = 33.1 bits (74), Expect = 0.61
Identities = 17/42 (40%), Positives = 23/42 (54%), Gaps = 3/42 (7%)
Frame = +2
Query: 386 KLLGKMFR-CTESGNYDSVQCIGSV--CFCANEHGQAIEGKQ 502
KLLG+ C E G Y QC GSV C+C + +G + G +
Sbjct: 332 KLLGQYIPLCDEDGYYKPTQCHGSVGQCWCVDRYGNEVMGSR 373
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 68,089,798
Number of Sequences: 369166
Number of extensions: 1420930
Number of successful extensions: 4505
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4071
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4428
length of database: 68,354,980
effective HSP length: 106
effective length of database: 48,773,070
effective search space used: 5072399280
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)