Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_007_D14
(627 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|P07954|FUMH_HUMAN Fumarate hydratase, mitochondrial prec... 246 4e-65
sp|P97807|FUMH_MOUSE Fumarate hydratase, mitochondrial prec... 246 4e-65
sp|Q60HF9|FUMH_MACFA Fumarate hydratase, mitochondrial prec... 246 4e-65
sp|P14408|FUMH_RAT Fumarate hydratase, mitochondrial precur... 244 1e-64
sp|P10173|FUMH_PIG Fumarate hydratase, mitochondrial (Fumar... 241 8e-64
sp|P93033|FUM1_ARATH Fumarate hydratase 1, mitochondrial pr... 240 2e-63
sp|Q7SX99|FUMH_BRARE Fumarate hydratase, mitochondrial prec... 240 2e-63
sp|P55250|FUMH_RHIOR Fumarate hydratase, mitochondrial prec... 239 4e-63
sp|Q9FI53|FUM2_ARATH Fumarate hydratase 2, chloroplast prec... 239 5e-63
sp|Q9ZCQ4|FUMC_RICPR Fumarate hydratase class II (Fumarase C) 234 2e-61
>sp|P07954|FUMH_HUMAN Fumarate hydratase, mitochondrial precursor (Fumarase)
Length = 510
Score = 246 bits (627), Expect = 4e-65
Identities = 116/182 (63%), Positives = 146/182 (80%)
Frame = +2
Query: 2 NTLATSLMKIANDFRFLGSGPRCGVGEFLLPENEPGSSIMPGKINPTQCESMSMVCAQVM 181
NT A SLMKIAND RFLGSGPR G+GE +LPENEPGSSIMPGK+NPTQCE+M+MV AQVM
Sbjct: 329 NTTACSLMKIANDIRFLGSGPRSGLGELILPENEPGSSIMPGKVNPTQCEAMTMVAAQVM 388
Query: 182 GNYVAISIGSSQGNLELNVYKPLIINNLLHSIQLLADCSKCFVKYCVSGLTLNTAQINTY 361
GN+VA+++G S G+ ELNV+KP++I N+LHS +LL D S F + CV G+ NT +IN
Sbjct: 389 GNHVAVTVGGSNGHFELNVFKPMMIKNVLHSARLLGDASVSFTENCVVGIQANTERINKL 448
Query: 362 VNQSLMLVTALNSHIGYDKSAQIAKYAHKNNCSLKEAAVQLKLVSDEDFDKWLDPWKMIS 541
+N+SLMLVTALN HIGYDK+A+IAK AHKN +LKE A++L ++ E FD+W+ P M+
Sbjct: 449 MNESLMLVTALNPHIGYDKAAKIAKTAHKNGSTLKETAIELGYLTAEQFDEWVKPKDMLG 508
Query: 542 PK 547
PK
Sbjct: 509 PK 510
>sp|P97807|FUMH_MOUSE Fumarate hydratase, mitochondrial precursor (Fumarase) (EF-3)
Length = 507
Score = 246 bits (627), Expect = 4e-65
Identities = 116/182 (63%), Positives = 146/182 (80%)
Frame = +2
Query: 2 NTLATSLMKIANDFRFLGSGPRCGVGEFLLPENEPGSSIMPGKINPTQCESMSMVCAQVM 181
NT A SLMKIAND RFLGSGPR G+GE +LPENEPGSSIMPGK+NPTQCE+M+MV AQVM
Sbjct: 326 NTAACSLMKIANDIRFLGSGPRSGLGELILPENEPGSSIMPGKVNPTQCEAMTMVAAQVM 385
Query: 182 GNYVAISIGSSQGNLELNVYKPLIINNLLHSIQLLADCSKCFVKYCVSGLTLNTAQINTY 361
GN+VA+++G S G+ ELNV+KP++I N+LHS +LL D S F + CV G+ NT +IN
Sbjct: 386 GNHVAVTVGGSNGHFELNVFKPMMIKNVLHSARLLGDASVSFTENCVVGIQANTERINKL 445
Query: 362 VNQSLMLVTALNSHIGYDKSAQIAKYAHKNNCSLKEAAVQLKLVSDEDFDKWLDPWKMIS 541
+N+SLMLVTALN HIGYDK+A+IAK AHKN +LKE A++L ++ E FD+W+ P M+
Sbjct: 446 MNESLMLVTALNPHIGYDKAAKIAKTAHKNGSTLKETAIELGYLTAEQFDEWVKPKDMLG 505
Query: 542 PK 547
PK
Sbjct: 506 PK 507
>sp|Q60HF9|FUMH_MACFA Fumarate hydratase, mitochondrial precursor (Fumarase)
Length = 510
Score = 246 bits (627), Expect = 4e-65
Identities = 116/182 (63%), Positives = 146/182 (80%)
Frame = +2
Query: 2 NTLATSLMKIANDFRFLGSGPRCGVGEFLLPENEPGSSIMPGKINPTQCESMSMVCAQVM 181
NT A SLMKIAND RFLGSGPR G+GE +LPENEPGSSIMPGK+NPTQCE+M+MV AQVM
Sbjct: 329 NTTACSLMKIANDIRFLGSGPRSGLGELILPENEPGSSIMPGKVNPTQCEAMTMVAAQVM 388
Query: 182 GNYVAISIGSSQGNLELNVYKPLIINNLLHSIQLLADCSKCFVKYCVSGLTLNTAQINTY 361
GN+VA+++G S G+ ELNV+KP++I N+LHS +LL D S F + CV G+ NT +IN
Sbjct: 389 GNHVAVTVGGSNGHFELNVFKPMMIKNVLHSARLLGDASVSFTENCVVGIQANTERINKL 448
Query: 362 VNQSLMLVTALNSHIGYDKSAQIAKYAHKNNCSLKEAAVQLKLVSDEDFDKWLDPWKMIS 541
+N+SLMLVTALN HIGYDK+A+IAK AHKN +LKE A++L ++ E FD+W+ P M+
Sbjct: 449 MNESLMLVTALNPHIGYDKAAKIAKTAHKNGSTLKETAIELGYLTAEQFDEWVKPKDMLG 508
Query: 542 PK 547
PK
Sbjct: 509 PK 510
>sp|P14408|FUMH_RAT Fumarate hydratase, mitochondrial precursor (Fumarase)
Length = 507
Score = 244 bits (623), Expect = 1e-64
Identities = 115/182 (63%), Positives = 146/182 (80%)
Frame = +2
Query: 2 NTLATSLMKIANDFRFLGSGPRCGVGEFLLPENEPGSSIMPGKINPTQCESMSMVCAQVM 181
NT A SLMKIAND RFLGSGPR G+GE +LPENEPGSSIMPGK+NPTQCE+M+MV AQVM
Sbjct: 326 NTTACSLMKIANDIRFLGSGPRSGLGELILPENEPGSSIMPGKVNPTQCEAMTMVAAQVM 385
Query: 182 GNYVAISIGSSQGNLELNVYKPLIINNLLHSIQLLADCSKCFVKYCVSGLTLNTAQINTY 361
GN+VA+++G S G+ ELNV+KP++I N+LHS +LL D S F + CV G+ NT +IN
Sbjct: 386 GNHVAVTVGGSNGHFELNVFKPMMIKNVLHSARLLGDASVSFTENCVVGIQANTERINKL 445
Query: 362 VNQSLMLVTALNSHIGYDKSAQIAKYAHKNNCSLKEAAVQLKLVSDEDFDKWLDPWKMIS 541
+N+SLMLVTALN HIGYDK+A+IAK AHKN +LK+ A++L ++ E FD+W+ P M+
Sbjct: 446 MNESLMLVTALNPHIGYDKAAKIAKTAHKNGSTLKKTAIELGYLTAEQFDEWVKPKDMLG 505
Query: 542 PK 547
PK
Sbjct: 506 PK 507
>sp|P10173|FUMH_PIG Fumarate hydratase, mitochondrial (Fumarase)
Length = 466
Score = 241 bits (616), Expect = 8e-64
Identities = 114/182 (62%), Positives = 145/182 (79%)
Frame = +2
Query: 2 NTLATSLMKIANDFRFLGSGPRCGVGEFLLPENEPGSSIMPGKINPTQCESMSMVCAQVM 181
NT A SLMKIAND RFLGSGPR G+GE +LPENEPGSSIMPGK+NPTQCE+++MV AQVM
Sbjct: 285 NTTACSLMKIANDIRFLGSGPRSGLGELILPENEPGSSIMPGKVNPTQCEALTMVAAQVM 344
Query: 182 GNYVAISIGSSQGNLELNVYKPLIINNLLHSIQLLADCSKCFVKYCVSGLTLNTAQINTY 361
GN+VA+++G S G+ ELNV+KP++I N+LHS +LL D + F + CV G+ NT +IN
Sbjct: 345 GNHVAVTVGGSNGHFELNVFKPMMIKNVLHSARLLGDAAVSFTENCVVGIQANTERINKL 404
Query: 362 VNQSLMLVTALNSHIGYDKSAQIAKYAHKNNCSLKEAAVQLKLVSDEDFDKWLDPWKMIS 541
+N+SLMLVTALN HIGYDK+A+IAK AHKN +LK AV+L ++ E FD+W+ P M+
Sbjct: 405 MNESLMLVTALNPHIGYDKAAKIAKTAHKNGSTLKATAVELGYLTAEQFDEWVKPRDMLG 464
Query: 542 PK 547
PK
Sbjct: 465 PK 466
>sp|P93033|FUM1_ARATH Fumarate hydratase 1, mitochondrial precursor (Fumarase 1)
Length = 492
Score = 240 bits (612), Expect = 2e-63
Identities = 113/181 (62%), Positives = 147/181 (81%)
Frame = +2
Query: 2 NTLATSLMKIANDFRFLGSGPRCGVGEFLLPENEPGSSIMPGKINPTQCESMSMVCAQVM 181
NT+ATSLMKIAND RFLGSGPRCG+GE +LPENEPGSSIMPGK+NPTQCE+++MVCAQVM
Sbjct: 310 NTIATSLMKIANDIRFLGSGPRCGLGELVLPENEPGSSIMPGKVNPTQCEALTMVCAQVM 369
Query: 182 GNYVAISIGSSQGNLELNVYKPLIINNLLHSIQLLADCSKCFVKYCVSGLTLNTAQINTY 361
GN+VA+++G S G+ ELNV+KP+I + LLHS++L+AD S F K CV G+ N +I+
Sbjct: 370 GNHVAVTVGGSNGHFELNVFKPVIASALLHSVRLIADASASFEKNCVRGIEANRERISKL 429
Query: 362 VNQSLMLVTALNSHIGYDKSAQIAKYAHKNNCSLKEAAVQLKLVSDEDFDKWLDPWKMIS 541
+++SLMLVT+LN IGYD +A +AK AHK C+LKEAA+ L +++ E+FD + P KMI
Sbjct: 430 LHESLMLVTSLNPKIGYDNAAAVAKKAHKEGCTLKEAALNLGVLTAEEFDTLVVPEKMIG 489
Query: 542 P 544
P
Sbjct: 490 P 490
>sp|Q7SX99|FUMH_BRARE Fumarate hydratase, mitochondrial precursor (Fumarase)
Length = 509
Score = 240 bits (612), Expect = 2e-63
Identities = 112/182 (61%), Positives = 148/182 (81%)
Frame = +2
Query: 2 NTLATSLMKIANDFRFLGSGPRCGVGEFLLPENEPGSSIMPGKINPTQCESMSMVCAQVM 181
NT+A S+MKIAND RFLGSGPR G+GE +LPENEPGSSIMPGK+NPTQCE+M+MV AQVM
Sbjct: 328 NTVAVSMMKIANDIRFLGSGPRSGLGELILPENEPGSSIMPGKVNPTQCEAMTMVAAQVM 387
Query: 182 GNYVAISIGSSQGNLELNVYKPLIINNLLHSIQLLADCSKCFVKYCVSGLTLNTAQINTY 361
GN+VA+++G S G+ ELNV+KP+II N+L+S +LL D S F CV G+ NT +IN
Sbjct: 388 GNHVAVTVGGSNGHFELNVFKPMIIKNVLNSARLLGDASVSFTNNCVVGIEANTERINKL 447
Query: 362 VNQSLMLVTALNSHIGYDKSAQIAKYAHKNNCSLKEAAVQLKLVSDEDFDKWLDPWKMIS 541
+++SLMLVTALN HIGYDK+A+IAK AHK+ +LKEAA++L ++++ F++W+ P M+
Sbjct: 448 MSESLMLVTALNPHIGYDKAAKIAKTAHKDGSTLKEAALKLGFLNEQQFEEWVRPHDMLG 507
Query: 542 PK 547
PK
Sbjct: 508 PK 509
>sp|P55250|FUMH_RHIOR Fumarate hydratase, mitochondrial precursor (Fumarase)
Length = 494
Score = 239 bits (610), Expect = 4e-63
Identities = 115/182 (63%), Positives = 144/182 (79%)
Frame = +2
Query: 2 NTLATSLMKIANDFRFLGSGPRCGVGEFLLPENEPGSSIMPGKINPTQCESMSMVCAQVM 181
NT+A SLMKIAND R+LGSGPRCG+GE LPENEPGSSIMPGK+NPTQCE+M+MVCAQVM
Sbjct: 312 NTVACSLMKIANDIRYLGSGPRCGLGELSLPENEPGSSIMPGKVNPTQCEAMTMVCAQVM 371
Query: 182 GNYVAISIGSSQGNLELNVYKPLIINNLLHSIQLLADCSKCFVKYCVSGLTLNTAQINTY 361
GN AIS+ S G ELNV+KP++I NL+ SI+L++D S F K CV G+ N +I++
Sbjct: 372 GNNTAISVAGSNGQFELNVFKPVMIKNLIQSIRLISDASISFTKNCVVGIEANEKKISSI 431
Query: 362 VNQSLMLVTALNSHIGYDKSAQIAKYAHKNNCSLKEAAVQLKLVSDEDFDKWLDPWKMIS 541
+N+SLMLVTALN HIGYDK+A+ AK AHK +LKEAA+ L ++ E+FD+W+ P MIS
Sbjct: 432 MNESLMLVTALNPHIGYDKAAKCAKKAHKEGTTLKEAALSLGYLTSEEFDQWVRPEDMIS 491
Query: 542 PK 547
K
Sbjct: 492 AK 493
>sp|Q9FI53|FUM2_ARATH Fumarate hydratase 2, chloroplast precursor (Fumarase 2)
Length = 499
Score = 239 bits (609), Expect = 5e-63
Identities = 114/181 (62%), Positives = 146/181 (80%)
Frame = +2
Query: 2 NTLATSLMKIANDFRFLGSGPRCGVGEFLLPENEPGSSIMPGKINPTQCESMSMVCAQVM 181
NT+ATSLMKIAND RFLGSGPRCG+GE LPENEPGSSIMPGK+NPTQCE+++MVCAQVM
Sbjct: 317 NTIATSLMKIANDIRFLGSGPRCGLGELSLPENEPGSSIMPGKVNPTQCEALTMVCAQVM 376
Query: 182 GNYVAISIGSSQGNLELNVYKPLIINNLLHSIQLLADCSKCFVKYCVSGLTLNTAQINTY 361
GN+VA++IG S G+ ELNV+KP+I + LLHSI+L+AD S F K CV G+ N +I+
Sbjct: 377 GNHVAVTIGGSNGHFELNVFKPVIASALLHSIRLIADASASFEKNCVRGIEANRERISKL 436
Query: 362 VNQSLMLVTALNSHIGYDKSAQIAKYAHKNNCSLKEAAVQLKLVSDEDFDKWLDPWKMIS 541
+++SLMLVT+LN IGYD +A +AK AHK C+LK AA++L +++ E+FD + P KMI
Sbjct: 437 LHESLMLVTSLNPKIGYDNAAAVAKRAHKEGCTLKHAAMKLGVLTSEEFDTLVVPEKMIG 496
Query: 542 P 544
P
Sbjct: 497 P 497
>sp|Q9ZCQ4|FUMC_RICPR Fumarate hydratase class II (Fumarase C)
Length = 461
Score = 234 bits (596), Expect = 2e-61
Identities = 116/180 (64%), Positives = 143/180 (79%)
Frame = +2
Query: 2 NTLATSLMKIANDFRFLGSGPRCGVGEFLLPENEPGSSIMPGKINPTQCESMSMVCAQVM 181
NT+A SLMKIAND R LGSGPRCG+GE LPENEPGSSIMPGK+NPTQ E+++MVC QVM
Sbjct: 282 NTIAVSLMKIANDIRLLGSGPRCGLGELHLPENEPGSSIMPGKVNPTQVEALTMVCTQVM 341
Query: 182 GNYVAISIGSSQGNLELNVYKPLIINNLLHSIQLLADCSKCFVKYCVSGLTLNTAQINTY 361
GN+V ++I S G+LELNV+KP+II N+L SI+LL+D FV +CV GL N A+INT
Sbjct: 342 GNHVTVTIAGSNGHLELNVFKPVIIYNILQSIELLSDSVNSFVTHCVKGLEPNIARINTL 401
Query: 362 VNQSLMLVTALNSHIGYDKSAQIAKYAHKNNCSLKEAAVQLKLVSDEDFDKWLDPWKMIS 541
++SLMLVT LN HIGYD +A+IAK AHK +LKEAA +L +S+E+FDK + P KMIS
Sbjct: 402 RDKSLMLVTVLNPHIGYDNAAKIAKEAHKYGITLKEAAKKLNFLSEEEFDKIVVPEKMIS 461
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 72,434,913
Number of Sequences: 369166
Number of extensions: 1456415
Number of successful extensions: 3976
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3876
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3969
length of database: 68,354,980
effective HSP length: 106
effective length of database: 48,773,070
effective search space used: 4974853140
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)