Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= Dr_sW_007_C16 (269 letters) Database: Non-redundant SwissProt sequences 184,735 sequences; 68,354,980 total letters Score E Sequences producing significant alignments: (bits) Value sp|P04069|CBPB_ASTFL Carboxypeptidase B 47 1e-05 sp|Q96IY4|CBPB2_HUMAN Carboxypeptidase B2 precursor (Carbox... 40 0.002 sp|P00730|CBPA1_BOVIN Carboxypeptidase A1 precursor 39 0.005 sp|Q9JHH6|CBPB2_MOUSE Carboxypeptidase B2 precursor (Carbox... 38 0.006 sp|Q7TPZ8|CBPA1_MOUSE Carboxypeptidase A1 precursor 38 0.008 sp|P00731|CBPA1_RAT Carboxypeptidase A1 precursor 38 0.008 sp|Q6P8K8|CBPA4_MOUSE Carboxypeptidase A4 precursor 37 0.019 sp|Q9EQV9|CBPB2_RAT Carboxypeptidase B2 precursor (Carboxyp... 36 0.024 sp|P15085|CBPA1_HUMAN Carboxypeptidase A1 precursor 35 0.054 sp|O02350|CBPA_ANOGA Zinc carboxypeptidase A precursor 34 0.093
>sp|P04069|CBPB_ASTFL Carboxypeptidase B Length = 303 Score = 47.4 bits (111), Expect = 1e-05 Identities = 29/67 (43%), Positives = 37/67 (55%) Frame = +1 Query: 13 GGAYDWIKTKTKVKYAYTLELRPSREYTTGLAGFLAPISYISRSGEEVYAGLLATVQAMT 192 GG+ DW K + VKYAYT+ELR TG GFL P + I +GEE + G V+ + Sbjct: 245 GGSDDWAKGEGGVKYAYTIELR-----DTGNYGFLLPENQIIPTGEETFEG----VKVVA 295 Query: 193 N*TKSKY 213 N K Y Sbjct: 296 NFVKDTY 302
>sp|Q96IY4|CBPB2_HUMAN Carboxypeptidase B2 precursor (Carboxypeptidase U) (Thrombin-activatable fibrinolysis inhibitor) (TAFI) (Plasma carboxypeptidase B) (pCPB) Length = 423 Score = 39.7 bits (91), Expect = 0.002 Identities = 23/55 (41%), Positives = 30/55 (54%) Frame = +1 Query: 4 LLPGGAYDWIKTKTKVKYAYTLELRPSREYTTGLAGFLAPISYISRSGEEVYAGL 168 L PGG DWI +KY++T+ELR TG GFL P YI + E +A + Sbjct: 364 LAPGGGDDWIYD-LGIKYSFTIELR-----DTGTYGFLLPERYIKPTCREAFAAV 412
>sp|P00730|CBPA1_BOVIN Carboxypeptidase A1 precursor Length = 419 Score = 38.5 bits (88), Expect = 0.005 Identities = 22/61 (36%), Positives = 33/61 (54%) Frame = +1 Query: 13 GGAYDWIKTKTKVKYAYTLELRPSREYTTGLAGFLAPISYISRSGEEVYAGLLATVQAMT 192 GG+ DW + +KY++T ELR TG GFL P S I + +E + G+L ++ Sbjct: 362 GGSIDWSYNQG-IKYSFTFELR-----DTGRYGFLLPASQIIPTAQETWLGVLTIMEHTL 415 Query: 193 N 195 N Sbjct: 416 N 416
>sp|Q9JHH6|CBPB2_MOUSE Carboxypeptidase B2 precursor (Carboxypeptidase U) (Thrombin-activatable fibrinolysis inhibitor) (TAFI) (Carboxypeptidase R) (CPR) Length = 422 Score = 38.1 bits (87), Expect = 0.006 Identities = 23/55 (41%), Positives = 30/55 (54%) Frame = +1 Query: 4 LLPGGAYDWIKTKTKVKYAYTLELRPSREYTTGLAGFLAPISYISRSGEEVYAGL 168 L PGG+ DWI +KY++T+ELR TG GFL P YI + E A + Sbjct: 363 LAPGGSDDWIYD-LGIKYSFTIELR-----DTGRYGFLLPERYIKPTCAEALAAI 411
>sp|Q7TPZ8|CBPA1_MOUSE Carboxypeptidase A1 precursor Length = 419 Score = 37.7 bits (86), Expect = 0.008 Identities = 22/53 (41%), Positives = 29/53 (54%) Frame = +1 Query: 13 GGAYDWIKTKTKVKYAYTLELRPSREYTTGLAGFLAPISYISRSGEEVYAGLL 171 G DW ++ +KY++T ELR TGL GFL P S I + EE + LL Sbjct: 362 GSTIDWTYSQG-IKYSFTFELRD-----TGLRGFLLPASQIIPTAEETWLALL 408
>sp|P00731|CBPA1_RAT Carboxypeptidase A1 precursor Length = 419 Score = 37.7 bits (86), Expect = 0.008 Identities = 22/53 (41%), Positives = 29/53 (54%) Frame = +1 Query: 13 GGAYDWIKTKTKVKYAYTLELRPSREYTTGLAGFLAPISYISRSGEEVYAGLL 171 G DW ++ +KY++T ELR TGL GFL P S I + EE + LL Sbjct: 362 GSTIDWTYSQG-IKYSFTFELRD-----TGLRGFLLPASQIIPTAEETWLALL 408
>sp|Q6P8K8|CBPA4_MOUSE Carboxypeptidase A4 precursor Length = 420 Score = 36.6 bits (83), Expect = 0.019 Identities = 22/52 (42%), Positives = 27/52 (51%) Frame = +1 Query: 13 GGAYDWIKTKTKVKYAYTLELRPSREYTTGLAGFLAPISYISRSGEEVYAGL 168 G + DW +KYA+T ELR TG GFL P S I + EE + GL Sbjct: 363 GSSVDWAYDNG-IKYAFTFELR-----DTGYYGFLLPASQIIPTAEETWLGL 408
>sp|Q9EQV9|CBPB2_RAT Carboxypeptidase B2 precursor (Carboxypeptidase U) (Thrombin-activatable fibrinolysis inhibitor) (TAFI) (Carboxypeptidase R) (CPR) Length = 422 Score = 36.2 bits (82), Expect = 0.024 Identities = 22/55 (40%), Positives = 30/55 (54%) Frame = +1 Query: 4 LLPGGAYDWIKTKTKVKYAYTLELRPSREYTTGLAGFLAPISYISRSGEEVYAGL 168 L PGG+ DWI +KY++T+ELR TG GFL P +I + E A + Sbjct: 363 LAPGGSDDWIYD-LGIKYSFTIELR-----DTGRYGFLLPERFIKPTCAEALAAV 411
>sp|P15085|CBPA1_HUMAN Carboxypeptidase A1 precursor Length = 419 Score = 35.0 bits (79), Expect = 0.054 Identities = 21/61 (34%), Positives = 31/61 (50%) Frame = +1 Query: 13 GGAYDWIKTKTKVKYAYTLELRPSREYTTGLAGFLAPISYISRSGEEVYAGLLATVQAMT 192 G DW ++ +KY++T ELR TG GFL P S I + +E + LL ++ Sbjct: 362 GSTIDWTYSQG-IKYSFTFELR-----DTGRYGFLLPASQIIPTAKETWLALLTIMEHTL 415 Query: 193 N 195 N Sbjct: 416 N 416
>sp|O02350|CBPA_ANOGA Zinc carboxypeptidase A precursor Length = 433 Score = 34.3 bits (77), Expect = 0.093 Identities = 20/57 (35%), Positives = 28/57 (49%) Frame = +1 Query: 13 GGAYDWIKTKTKVKYAYTLELRPSREYTTGLAGFLAPISYISRSGEEVYAGLLATVQ 183 G + DW VK AYT ELRP + GF+ P + I +GEE L+ ++ Sbjct: 368 GSSVDWSYGAQDVKIAYTYELRPDGD---AWNGFVLPPNEIVPTGEETLDSLITLLE 421
Database: Non-redundant SwissProt sequences Posted date: Dec 6, 2005 7:40 AM Number of letters in database: 68,354,980 Number of sequences in database: 184,735 Database: swissprot.01 Posted date: Dec 6, 2005 8:18 AM Number of letters in database: 66,202,850 Number of sequences in database: 184,431 Lambda K H 0.318 0.134 0.401 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 27,670,379 Number of Sequences: 369166 Number of extensions: 441380 Number of successful extensions: 990 Number of sequences better than 10.0: 10 Number of HSP's better than 10.0 without gapping: 984 Number of HSP's successfully gapped in prelim test: 0 Number of HSP's that attempted gapping in prelim test: 0 Number of HSP's gapped (non-prelim): 987 length of database: 68,354,980 effective HSP length: 59 effective length of database: 57,455,615 effective search space used: 1723668450 frameshift window, decay const: 40, 0.1 T: 12 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits)