Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_007_C15
(447 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q9QZA6|CD151_RAT Platelet endothelial tetraspan antigen ... 71 1e-12
sp|P48509|CD151_HUMAN Platelet-endothelial tetraspan antige... 69 6e-12
sp|O35566|C151_MOUSE Platelet-endothelial tetraspan antigen... 68 1e-11
sp|Q9XSK2|CD63_BOVIN CD63 antigen 64 2e-10
sp|O43657|TSN6_HUMAN Tetraspanin-6 (Tspan-6) (Transmembrane... 62 4e-10
sp|O70401|TSN6_MOUSE Tetraspanin-6 (Tspan-6) (Transmembrane... 62 4e-10
sp|P61171|CD151_MACMU Platelet-endothelial tetraspan antige... 62 6e-10
sp|P28648|CD63_RAT CD63 antigen (AD1 antigen) 59 4e-09
sp|P08962|CD63_HUMAN CD63 antigen (Melanoma-associated anti... 59 5e-09
sp|Q28709|CD63_RABIT CD63 antigen 59 6e-09
>sp|Q9QZA6|CD151_RAT Platelet endothelial tetraspan antigen 3 (CD151 antigen)
Length = 253
Score = 70.9 bits (172), Expect = 1e-12
Identities = 31/106 (29%), Positives = 56/106 (52%), Gaps = 2/106 (1%)
Frame = +1
Query: 7 VTKTVDSLQQAMQCCGATKMTDWLQSDWYQNSKNKTQPFPSSCCDPITSPCWELGYDKKA 186
VT VD LQQ CCG+ DW S+W ++ + ++ P SCC + + C + +
Sbjct: 142 VTNAVDKLQQEFHCCGSNNSRDWRDSEWIRSGEADSRVVPDSCCKTVVTGCGKREHASNI 201
Query: 187 F--TDGCIPKMFSYAKTYFPLVIGITLGIAFFEIFVVVCAFCLCRN 318
+ GCI K+ S+ + + ++ + +GIA ++F ++ CL R+
Sbjct: 202 YKVEGGCITKLESFIQEHLRVIGAVGIGIACVQVFGMIFTCCLYRS 247
>sp|P48509|CD151_HUMAN Platelet-endothelial tetraspan antigen 3 (PETA-3) (GP27) (Membrane
glycoprotein SFA-1) (CD151 antigen) (Tetraspanin-24)
(Tspan-24)
Length = 253
Score = 68.6 bits (166), Expect = 6e-12
Identities = 30/106 (28%), Positives = 55/106 (51%), Gaps = 2/106 (1%)
Frame = +1
Query: 7 VTKTVDSLQQAMQCCGATKMTDWLQSDWYQNSKNKTQPFPSSCCDPITSPCWELGYDKKA 186
VT VD LQQ CCG+ DW S+W ++ + + P SCC + + C + +
Sbjct: 142 VTSAVDQLQQEFHCCGSNNSQDWRDSEWIRSQEAGGRVVPDSCCKTVVALCGQRDHASNI 201
Query: 187 F--TDGCIPKMFSYAKTYFPLVIGITLGIAFFEIFVVVCAFCLCRN 318
+ GCI K+ ++ + + ++ + +GIA ++F ++ CL R+
Sbjct: 202 YKVEGGCITKLETFIQEHLRVIGAVGIGIACVQVFGMIFTCCLYRS 247
>sp|O35566|C151_MOUSE Platelet-endothelial tetraspan antigen 3 (PETA-3) (GP27) (Membrane
glycoprotein SFA-1) (CD151 antigen)
Length = 253
Score = 67.8 bits (164), Expect = 1e-11
Identities = 29/106 (27%), Positives = 56/106 (52%), Gaps = 2/106 (1%)
Frame = +1
Query: 7 VTKTVDSLQQAMQCCGATKMTDWLQSDWYQNSKNKTQPFPSSCCDPITSPCWELGYDKKA 186
V+ VD LQQ CCG+ DW S+W ++ + ++ P SCC + + C + +
Sbjct: 142 VSSAVDKLQQEFHCCGSNNSQDWQDSEWIRSGEADSRVVPDSCCKTMVAGCGKRDHASNI 201
Query: 187 F--TDGCIPKMFSYAKTYFPLVIGITLGIAFFEIFVVVCAFCLCRN 318
+ GCI K+ ++ + + ++ + +GIA ++F ++ CL R+
Sbjct: 202 YKVEGGCITKLETFIQEHLRVIGAVGIGIACVQVFGMIFTCCLYRS 247
>sp|Q9XSK2|CD63_BOVIN CD63 antigen
Length = 237
Score = 63.9 bits (154), Expect = 2e-10
Identities = 34/100 (34%), Positives = 50/100 (50%)
Frame = +1
Query: 19 VDSLQQAMQCCGATKMTDWLQSDWYQNSKNKTQPFPSSCCDPITSPCWELGYDKKAFTDG 198
+D +Q+ +CCGA TDW + T P SCC IT C K T+G
Sbjct: 136 LDKMQKDFECCGAANYTDW------EKILAVTNKVPDSCCVNITHNCGINFVVKDIHTEG 189
Query: 199 CIPKMFSYAKTYFPLVIGITLGIAFFEIFVVVCAFCLCRN 318
C+ K+ ++ + +V+ LGIAF EI +V A CL ++
Sbjct: 190 CVEKIAAWLRKNVLVVVAAALGIAFVEILGIVLACCLVKS 229
>sp|O43657|TSN6_HUMAN Tetraspanin-6 (Tspan-6) (Transmembrane 4 superfamily member 6)
(T245 protein) (Tetraspanin TM4-D) (A15 homolog)
Length = 245
Score = 62.4 bits (150), Expect = 4e-10
Identities = 31/105 (29%), Positives = 50/105 (47%)
Frame = +1
Query: 19 VDSLQQAMQCCGATKMTDWLQSDWYQNSKNKTQPFPSSCCDPITSPCWELGYDKKAFTDG 198
VD +Q + CCG T DW +++Y + FP SCC C K +G
Sbjct: 144 VDKIQNTLHCCGVTDYRDWTDTNYYSE-----KGFPKSCCK--LEDCTPQRDADKVNNEG 196
Query: 199 CIPKMFSYAKTYFPLVIGITLGIAFFEIFVVVCAFCLCRNTVQHQ 333
C K+ + ++ +V GI+ G+A F++ + A+CL R +Q
Sbjct: 197 CFIKVMTIIESEMGVVAGISFGVACFQLIGIFLAYCLSRAITNNQ 241
>sp|O70401|TSN6_MOUSE Tetraspanin-6 (Tspan-6) (Transmembrane 4 superfamily member 6)
Length = 245
Score = 62.4 bits (150), Expect = 4e-10
Identities = 31/108 (28%), Positives = 53/108 (49%)
Frame = +1
Query: 10 TKTVDSLQQAMQCCGATKMTDWLQSDWYQNSKNKTQPFPSSCCDPITSPCWELGYDKKAF 189
++ VD +Q + CCG T DW +++Y + FP SCC C+ K
Sbjct: 141 SEAVDKIQSTLHCCGVTNYGDWKGTNYYSETG-----FPKSCCK--LEGCYPQRDADKVN 193
Query: 190 TDGCIPKMFSYAKTYFPLVIGITLGIAFFEIFVVVCAFCLCRNTVQHQ 333
+GC K+ + ++ +V GI+ G+A F++ + A+CL R +Q
Sbjct: 194 EEGCFIKVMTTIESEMGVVAGISFGVACFQLIGIFLAYCLSRAITNNQ 241
>sp|P61171|CD151_MACMU Platelet-endothelial tetraspan antigen 3 (PETA-3) (CD151 antigen)
sp|P61170|CD151_CERAE Platelet-endothelial tetraspan antigen 3 (PETA-3) (CD151 antigen)
Length = 253
Score = 62.0 bits (149), Expect = 6e-10
Identities = 29/106 (27%), Positives = 53/106 (50%), Gaps = 2/106 (1%)
Frame = +1
Query: 7 VTKTVDSLQQAMQCCGATKMTDWLQSDWYQNSKNKTQPFPSSCCDPITSPCWELGYDKKA 186
VT VD LQQ CCG+ DW S+W + + + + P SCC + + C + +
Sbjct: 142 VTSAVDQLQQEFHCCGSNNSQDWRDSEWIRLREARGRVVPDSCCKTVVAGCGQRDHAFNI 201
Query: 187 F--TDGCIPKMFSYAKTYFPLVIGITLGIAFFEIFVVVCAFCLCRN 318
+ G I K+ ++ + + ++ + GIA ++F ++ CL R+
Sbjct: 202 YKVEGGFITKLETFIQEHLRVIGAVGTGIACVQVFGMIFTCCLYRS 247
>sp|P28648|CD63_RAT CD63 antigen (AD1 antigen)
Length = 238
Score = 59.3 bits (142), Expect = 4e-09
Identities = 31/100 (31%), Positives = 49/100 (49%)
Frame = +1
Query: 19 VDSLQQAMQCCGATKMTDWLQSDWYQNSKNKTQPFPSSCCDPITSPCWELGYDKKAFTDG 198
+D LQ+ +CCGA+ TDW + + P SCC IT C + T G
Sbjct: 136 LDKLQKENKCCGASNYTDWERIPGMAKDR-----VPDSCCINITVGCGNDFKESTIHTQG 190
Query: 199 CIPKMFSYAKTYFPLVIGITLGIAFFEIFVVVCAFCLCRN 318
C+ + ++ + LV G LGIAF E+ ++ + CL ++
Sbjct: 191 CVETIAAWLRKNVLLVAGAALGIAFVEVLGIIFSCCLVKS 230
>sp|P08962|CD63_HUMAN CD63 antigen (Melanoma-associated antigen ME491)
(Lysosome-associated membrane glycoprotein 3) (LAMP-3)
(Ocular melanoma-associated antigen) (OMA81H)
(Granulophysin) (Tetraspanin-30) (Tspan-30)
Length = 238
Score = 58.9 bits (141), Expect = 5e-09
Identities = 33/100 (33%), Positives = 50/100 (50%)
Frame = +1
Query: 19 VDSLQQAMQCCGATKMTDWLQSDWYQNSKNKTQPFPSSCCDPITSPCWELGYDKKAFTDG 198
+D +Q +CCGA TDW + SKN+ P SCC +T C +K +G
Sbjct: 136 LDRMQADFKCCGAANYTDWEKIP--SMSKNRV---PDSCCINVTVGCGINFNEKAIHKEG 190
Query: 199 CIPKMFSYAKTYFPLVIGITLGIAFFEIFVVVCAFCLCRN 318
C+ K+ + + +V LGIAF E+ +V A CL ++
Sbjct: 191 CVEKIGGWLRKNVLVVAAAALGIAFVEVLGIVFACCLVKS 230
>sp|Q28709|CD63_RABIT CD63 antigen
Length = 238
Score = 58.5 bits (140), Expect = 6e-09
Identities = 31/100 (31%), Positives = 47/100 (47%)
Frame = +1
Query: 19 VDSLQQAMQCCGATKMTDWLQSDWYQNSKNKTQPFPSSCCDPITSPCWELGYDKKAFTDG 198
+D +Q+ CCGA TDW + P SCC +TS C K + +G
Sbjct: 136 LDRMQKDFTCCGAANYTDWATIPGMTRDR-----VPDSCCVNVTSGCGVKFNVKDIYVEG 190
Query: 199 CIPKMFSYAKTYFPLVIGITLGIAFFEIFVVVCAFCLCRN 318
C+ K+ + + +V LGIAF E+ +V A CL ++
Sbjct: 191 CVEKIGLWLRKNVLVVAAAALGIAFVEVLGIVFACCLVKS 230
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 53,492,829
Number of Sequences: 369166
Number of extensions: 1050320
Number of successful extensions: 2570
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 2491
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 2540
length of database: 68,354,980
effective HSP length: 100
effective length of database: 49,881,480
effective search space used: 2394311040
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)