Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_007_B19
(793 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q4X1D7|CWC25_ASPFU Pre-mRNA splicing factor cwc25 45 3e-04
sp|Q9QX47|SON_MOUSE SON protein 40 0.006
sp|Q5T200|K0853_HUMAN Protein KIAA0853 40 0.006
sp|O01159|RSP7_CAEEL Probable splicing factor, arginine/ser... 39 0.016
sp|P39936|IF4F2_YEAST Eukaryotic initiation factor 4F subun... 39 0.021
sp|Q61136|PRP4B_MOUSE Serine/threonine-protein kinase PRP4 ... 39 0.021
sp|Q99MR6|ARS2_MOUSE Arsenite-resistance protein 2 39 0.021
sp|P25555|GBP2_YEAST Single-strand telomeric DNA-binding pr... 39 0.021
sp|P18583|SON_HUMAN SON protein (SON3) (Negative regulatory... 39 0.021
sp|Q9BXP5|ARS2_HUMAN Arsenite-resistance protein 2 39 0.021
>sp|Q4X1D7|CWC25_ASPFU Pre-mRNA splicing factor cwc25
Length = 447
Score = 44.7 bits (104), Expect = 3e-04
Identities = 60/228 (26%), Positives = 85/228 (37%), Gaps = 19/228 (8%)
Frame = +2
Query: 83 RRSPADYRKEISRNRAMSPPRKEYSMRDLSPRVREISPRMRDVEPRIRDVEPRIRDMDPR 262
RR D ++ SR+R S R + D R S R R P D R R D
Sbjct: 177 RRDRGD--RDRSRDRDRSHRRSRHEDEDAHRSHRHRSHRHRSRSPLSPDRSDRKRGDDRD 234
Query: 263 FRDYAPR--SRNFENRSRDGRRDYSPNA--------RDRHFSPVRYQHDRYEYSPPRSRN 412
+RD R R E+R D R D DRH S + + DRY++S R
Sbjct: 235 YRDERDRRDDRRDEHRGHDRRDDRRSERDRRADRGDEDRHSSRYKDRDDRYDHSTRRRSY 294
Query: 413 YERDNFP-------ERRRNDVRPFXXXXXXXXXXXXXXXFRPRGGRFNSQRGNTRGRDNL 571
+R P +RRR + R RP R N ++ N R
Sbjct: 295 ADRSPSPRRGNHYYDRRRTEDR------SDGYHRDSRNHDRPEFYRGNDRKVNKEPR--- 345
Query: 572 NRFDSNQRNNYNRPRDESSMRRGHINDNPKRK--VEQVPNSGIPPQKK 709
DSN R + RDE + + + + ++K E + N+ QK+
Sbjct: 346 ---DSNLRERSSNTRDEVAGNKEKVLEEERKKKLAEMMSNADELEQKR 390
>sp|Q9QX47|SON_MOUSE SON protein
Length = 2404
Score = 40.4 bits (93), Expect = 0.006
Identities = 36/116 (31%), Positives = 50/116 (43%), Gaps = 9/116 (7%)
Frame = +2
Query: 119 RNRAMSPPRKEYSMR-------DLSPRVREISPRMRDVEPRIRDVEPRIRDMDPRFRDYA 277
R+R+ +P R+ S+ +SP R +P R P R P R P R
Sbjct: 1913 RSRSHTPSRRRRSISVGRRRSFSISPSRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRSRT 1972
Query: 278 PRSRNFENRSRDGRRDYS--PNARDRHFSPVRYQHDRYEYSPPRSRNYERDNFPER 439
P SR +RS RR +S P R +P+R + R RSR+ ER P+R
Sbjct: 1973 P-SRRRRSRSAVRRRSFSISPVRLRRSRTPLRRRFSRSPIRRKRSRSSERGRSPKR 2027
>sp|Q5T200|K0853_HUMAN Protein KIAA0853
Length = 1668
Score = 40.4 bits (93), Expect = 0.006
Identities = 64/231 (27%), Positives = 90/231 (38%), Gaps = 17/231 (7%)
Frame = +2
Query: 80 MRRSPADYRKEI--SRNRAMSPPRKEYSMRDLSPRVREISPRMRDVEPRIRDVEPRIRDM 253
+RRS + Y S R SPPR MR+ E + + D R+ RD
Sbjct: 367 LRRSASPYPSHSLSSPQRKQSPPRHRSPMREKGRHDHERTSQSHDRRHERREDTRGKRDR 426
Query: 254 DPRFRDYAPRSRNFENRSRDGRRDYSP-NARDRHFSPVRYQHDRYEYSPPRS-------R 409
+ R+ ++ ++ SRD R D P + RDR R DR E R R
Sbjct: 427 EKDSREEREYEQD-QSSSRDHRDDREPRDGRDRR--DARDTRDRRELRDSRDMRDSREMR 483
Query: 410 NYERDNFPERRRNDVRPFXXXXXXXXXXXXXXXFRPRGGRFNSQRGNT-------RGRDN 568
+Y RD R D R +R R GR ++ +T GR++
Sbjct: 484 DYSRDTKESRDPRDSR----------STRDAHDYRDREGRDTHRKEDTYPEESRSYGRNH 533
Query: 569 LNRFDSNQRNNYNRPRDESSMRRGHINDNPKRKVEQVPNSGIPPQKKSRDS 721
L R +S++ N R+ES R ND R +VP P+K SR S
Sbjct: 534 L-REESSRTEIRNESRNES--RSEIRNDRMGRSRGRVPEL---PEKGSRGS 578
Score = 32.3 bits (72), Expect = 1.5
Identities = 45/221 (20%), Positives = 72/221 (32%)
Frame = +2
Query: 98 DYRKEISRNRAMSPPRKEYSMRDLSPRVREISPRMRDVEPRIRDVEPRIRDMDPRFRDYA 277
D R+E R + R E + R R+ R R+ E R R+
Sbjct: 657 DERREERRVDRVDDRRDERARERDRERERDRERERERERERDREREKERELERERARERE 716
Query: 278 PRSRNFENRSRDGRRDYSPNARDRHFSPVRYQHDRYEYSPPRSRNYERDNFPERRRNDVR 457
+R RD RD+ + +R R R ER+ ER R
Sbjct: 717 REREKERDRERDRDRDHDRERERERERDREKEREREREERERERERERERERERERE--- 773
Query: 458 PFXXXXXXXXXXXXXXXFRPRGGRFNSQRGNTRGRDNLNRFDSNQRNNYNRPRDESSMRR 637
R R + +R R ++ ++ ++R R++ + R
Sbjct: 774 ------------------RERARERDKERERQRDWEDKDKGRDDRREKREEIREDRNPRD 815
Query: 638 GHINDNPKRKVEQVPNSGIPPQKKSRDSSFETSP*ELLFNS 760
GH K++ N G P ++S E SP +NS
Sbjct: 816 GHDERKSKKRYR---NEGSPSPRQSPKRRREHSPDSDAYNS 853
Score = 30.4 bits (67), Expect = 5.8
Identities = 37/121 (30%), Positives = 42/121 (34%), Gaps = 10/121 (8%)
Frame = +2
Query: 125 RAMSPPRKEYSMRDLSPRVREISPRMRDVEPRIRDVEPRIRDMDPRF-------RDYAPR 283
R+ P R Y RD + R+ S R E RD R RD P D R
Sbjct: 599 RSSYPERDRYPERDNRDQARDSSFERRHGERDRRD--NRERDQRPSSPIRHQGRNDELER 656
Query: 284 SRNFENRSRD---GRRDYSPNARDRHFSPVRYQHDRYEYSPPRSRNYERDNFPERRRNDV 454
E R D RRD RDR R + E R R ER+ ER R
Sbjct: 657 DERREERRVDRVDDRRDERARERDRERERDRERERERERERDREREKERELERERARERE 716
Query: 455 R 457
R
Sbjct: 717 R 717
Score = 29.6 bits (65), Expect = 9.8
Identities = 30/139 (21%), Positives = 57/139 (41%), Gaps = 25/139 (17%)
Frame = +2
Query: 107 KEISRNRAMSPPRKEYSMRDLSPRVREISPRMRDVEPRIRD---------VEPRIRD-MD 256
K+ + A+S P + + + ++ PR P I + + +++D ++
Sbjct: 232 KKDRKTSAVSSPLLDQQRNSKTNQSKKKGPRTPSPPPPIPEDIALGKKYKEKYKVKDRIE 291
Query: 257 PRFRDYAPRSRNFENRSRDGRRDYSPNARDRHFSPVRYQH-----------DRYEYSPPR 403
+ RD R R+FE + + S + +H SP+ +H R+ SP R
Sbjct: 292 EKTRDGKDRGRDFERQREKRDKPRSTSPAGQHHSPISSRHHSSSSQSGSSIQRHSPSPRR 351
Query: 404 SR----NYERDNFPERRRN 448
R +Y+R P RR+
Sbjct: 352 KRTPSPSYQRTLTPPLRRS 370
>sp|O01159|RSP7_CAEEL Probable splicing factor, arginine/serine-rich 7 (p54)
Length = 452
Score = 38.9 bits (89), Expect = 0.016
Identities = 49/211 (23%), Positives = 73/211 (34%), Gaps = 13/211 (6%)
Frame = +2
Query: 146 KEYSMRDLSPRVREISPRMRDVEPRIRDVEPRIR-----DMDPRFRDYAPRSRNFENRSR 310
KE ++ RV I P+ + E + ++E IR D R R +PR R + R
Sbjct: 229 KERPLKIQHSRVAIIKPQAKTDEQALGEIEEAIRMGRNGDDRDRRRSRSPRRRRSPSPRR 288
Query: 311 DGRRDYSPNARDRHFSPVRYQHDRYEYSPPRSRNYERDNFPERRRNDVRPFXXXXXXXXX 490
RRD RDR DR RSR+ +RD +R+R+ R
Sbjct: 289 --RRDSRDRDRDR-------DRDRRRSRDRRSRSRDRDRDRDRKRSRSRDRKRRSRSRDN 339
Query: 491 XXXXXXFRPRGGRFNSQRGNTRGRDNLNRFDSNQRNNYNRPRDESSMRRGHINDNPKRKV 670
R + R R+ +++ + R R S +R D K
Sbjct: 340 KDRDRKRSRSRDRRRRSKSRDRKRERSRSRSKDRKRDKKRSRSRSPEKRRDKEDRKTEKK 399
Query: 671 EQVPNSGI--------PPQKKSRDSSFETSP 739
E S + +K S D +E P
Sbjct: 400 ENENESSLREKLLEKKAARKDSSDDEWEEKP 430
>sp|P39936|IF4F2_YEAST Eukaryotic initiation factor 4F subunit p130 (eIF4F p130) (eIF-4F
p130) (mRNA cap-binding protein complex subunit p130)
Length = 914
Score = 38.5 bits (88), Expect = 0.021
Identities = 24/56 (42%), Positives = 33/56 (58%), Gaps = 7/56 (12%)
Frame = +2
Query: 533 NSQRGNTR----GRDNLNRFDSNQRNNYNRPRDE-SSMRRGHINDNPK--RKVEQV 679
NSQR N+R + N NR+ SN+RN N RD +S + G +N + RKVE+V
Sbjct: 839 NSQRSNSRFNNHNQSNSNRYSSNRRNMQNTQRDSFASTKTGSFRNNQRNARKVEEV 894
>sp|Q61136|PRP4B_MOUSE Serine/threonine-protein kinase PRP4 homolog (PRP4 pre-mRNA
processing factor 4 homolog) (Pre-mRNA protein kinase)
Length = 1007
Score = 38.5 bits (88), Expect = 0.021
Identities = 49/203 (24%), Positives = 74/203 (36%), Gaps = 17/203 (8%)
Frame = +2
Query: 86 RSPADYRKEISRNRAMSPPRK------EYSMRDLSPRVREISPRMRDVEPRIRDVE-PRI 244
+SP D R + R+ S RK + + + ++ S + P R P+
Sbjct: 293 KSPVDLRDKSKDRRSRSKERKSKRSEIDKEKKPIKSPSKDASSGKENRSPSRRPGRSPKR 352
Query: 245 RDMDPRFRDYAPRSRNFENRSRDGRRDYSPN--------ARDRHFSPVRYQHDRYEYSPP 400
R + P+ RD + RSR+ R ++ SP+ A+ R R + +R S P
Sbjct: 353 RSLSPKLRDKSRRSRSPLLNDRRSKQSKSPSRTLSPGRRAKSRSLERKRREPERRRLSSP 412
Query: 401 RSRNYERDNFPER--RRNDVRPFXXXXXXXXXXXXXXXFRPRGGRFNSQRGNTRGRDNLN 574
R+R RD+ R R D P R R S+ R R
Sbjct: 413 RTR--PRDDILGRCERSKDASPINRWSPTRRRSRSPIRRRSRSPLRRSRSPRRRSRSPRR 470
Query: 575 RFDSNQRNNYNRPRDESSMRRGH 643
R R + +R R S R GH
Sbjct: 471 R--DRSRRSKSRLRRRSRSRGGH 491
Score = 32.3 bits (72), Expect = 1.5
Identities = 36/98 (36%), Positives = 42/98 (42%), Gaps = 19/98 (19%)
Frame = +2
Query: 86 RSPADYRKEISRNRAMSP---PRKEYSMR-----DLSP-------RVREISP-RMRDVEP 217
RS R+E R R SP PR + R D SP R R SP R R P
Sbjct: 395 RSLERKRREPERRRLSSPRTRPRDDILGRCERSKDASPINRWSPTRRRSRSPIRRRSRSP 454
Query: 218 RIRDVEPRIRDMDPRFRDYAPRSRN---FENRSRDGRR 322
R PR R PR RD + RS++ +RSR G R
Sbjct: 455 LRRSRSPRRRSRSPRRRDRSRRSKSRLRRRSRSRGGHR 492
>sp|Q99MR6|ARS2_MOUSE Arsenite-resistance protein 2
Length = 875
Score = 38.5 bits (88), Expect = 0.021
Identities = 33/79 (41%), Positives = 38/79 (48%), Gaps = 4/79 (5%)
Frame = +2
Query: 185 EISPRMRDVEPRIRDVEPRIRDMDPRFR--DYAPRS--RNFENRSRDGRRDYSPNARDRH 352
E R RD R R R R+ D R R D+ R R E RSR RDY N R+R
Sbjct: 7 EYDRRRRDKFRRERSDYDRSRERDERRRGDDWNDREWDRGRERRSRGEYRDYDRNRRER- 65
Query: 353 FSPVRYQHDRYEYSPPRSR 409
FSP R+E SPP+ R
Sbjct: 66 FSP-----PRHELSPPQKR 79
>sp|P25555|GBP2_YEAST Single-strand telomeric DNA-binding protein GBP2 (G-strand binding
protein 2) (RAP1 localization factor 6)
Length = 427
Score = 38.5 bits (88), Expect = 0.021
Identities = 44/134 (32%), Positives = 54/134 (40%), Gaps = 8/134 (5%)
Frame = +2
Query: 230 VEPRIRDMDPRFRDYAPRSRNFENRSRDGRRDYSPNARDRHFSPVRYQHDRYEYSPPRSR 409
V R+ D R+ DY S N N SR RRD R F +DRY+ S SR
Sbjct: 19 VRRRLSDDRDRYDDYNDSSSNNGNGSRRQRRD-----RGSRF------NDRYDQSYGGSR 67
Query: 410 NYERDNFPERR----RNDVRPFXXXXXXXXXXXXXXXFRPRGGRFNSQRGNTRG----RD 565
++ N+P RR R R F RGGR RG T G RD
Sbjct: 68 YHDDRNWPPRRGGRGRGGSRSF------------------RGGR-GGGRGRTLGPIVERD 108
Query: 566 NLNRFDSNQRNNYN 607
+FD+ +RN N
Sbjct: 109 LERQFDATKRNFEN 122
>sp|P18583|SON_HUMAN SON protein (SON3) (Negative regulatory element-binding protein)
(NRE-binding protein) (DBP-5) (Bax antagonist selected in
saccharomyces 1) (BASS1)
Length = 2426
Score = 38.5 bits (88), Expect = 0.021
Identities = 47/142 (33%), Positives = 56/142 (39%), Gaps = 23/142 (16%)
Frame = +2
Query: 83 RRSPADYRKEIS--------RNRAMSPPRKEYSMRDLSPRVREISPRMRDVEPRIRDVEP 238
R S D RK + R+R+ +P R+ S R ISP R P R P
Sbjct: 1908 RSSSRDNRKTVRARSRTPSRRSRSHTPSRRRRSRSVGRRRSFSISPSRRSRTPSRRSRTP 1967
Query: 239 RIRDMDPRFRDYAP--RSRNFENRSR--DGRRDYSPNARDRHFS--PVRYQHDR------ 382
R P R P RSR RSR RR R R FS PVR + R
Sbjct: 1968 SRRSRTPSRRSRTPSRRSRTPSRRSRTPSRRRRSRSVVRRRSFSISPVRLRRSRTPLRRR 2027
Query: 383 YEYSP---PRSRNYERDNFPER 439
+ SP RSR+ ER P+R
Sbjct: 2028 FSRSPIRRKRSRSSERGRSPKR 2049
>sp|Q9BXP5|ARS2_HUMAN Arsenite-resistance protein 2
Length = 876
Score = 38.5 bits (88), Expect = 0.021
Identities = 33/79 (41%), Positives = 38/79 (48%), Gaps = 4/79 (5%)
Frame = +2
Query: 185 EISPRMRDVEPRIRDVEPRIRDMDPRFR--DYAPRS--RNFENRSRDGRRDYSPNARDRH 352
E R RD R R R R+ D R R D+ R R E RSR RDY N R+R
Sbjct: 7 EYDRRRRDKFRRERSDYDRSRERDERRRGDDWNDREWDRGRERRSRGEYRDYDRNRRER- 65
Query: 353 FSPVRYQHDRYEYSPPRSR 409
FSP R+E SPP+ R
Sbjct: 66 FSP-----PRHELSPPQKR 79
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 75,840,317
Number of Sequences: 369166
Number of extensions: 1497420
Number of successful extensions: 4839
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 4220
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 4656
length of database: 68,354,980
effective HSP length: 109
effective length of database: 48,218,865
effective search space used: 7425705210
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)