Reference:
Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= Dr_sW_007_B13
(867 letters)
Database: Non-redundant SwissProt sequences
184,735 sequences; 68,354,980 total letters
Score E
Sequences producing significant alignments: (bits) Value
sp|Q19958|STO2_CAEEL Stomatin protein 2 252 8e-67
sp|Q27433|MEC2_CAEEL Mechanosensory protein 2 251 2e-66
sp|P27105|STOM_HUMAN Erythrocyte band 7 integral membrane p... 248 1e-65
sp|P54116|STOM_MOUSE Erythrocyte band 7 integral membrane p... 248 2e-65
sp|Q22165|STO4_CAEEL Stomatin protein 4 246 6e-65
sp|Q8TAV4|STML3_HUMAN Stomatin-like protein 3 244 2e-64
sp|Q6PE84|STML3_MOUSE Stomatin-like protein 3 (Stomatin-rel... 244 2e-64
sp|Q21190|UNC1_CAEEL Uncoordinated protein 1 (Protein unc-1) 226 8e-59
sp|Q19200|STO1_CAEEL Stomatin protein 1 222 9e-58
sp|Q20657|STO3_CAEEL Stomatin protein 3 211 2e-54
>sp|Q19958|STO2_CAEEL Stomatin protein 2
Length = 314
Score = 252 bits (644), Expect = 8e-67
Identities = 126/217 (58%), Positives = 164/217 (75%)
Frame = +2
Query: 215 ISLFILVVFFPISLFFCLTVVAQYERAVIFRLGRLQGKGPKGPGLVFIIPCLDSIRKIDL 394
+S +++ FP+S++FC+ VV +YERAVIFRLGRL G G KGPG+ F++PC++S K+DL
Sbjct: 76 LSWIMVISTFPVSIYFCMKVVQEYERAVIFRLGRLIGGGAKGPGIFFVLPCIESYTKVDL 135
Query: 395 RTFTFNIPTQEVLTKDSVTVAVDAVVYYRIFNPVMSIVNVENANRSTKLLAQTTLRTVLG 574
RT +F++P QE+LTKDSVT +VDAV+YYRI N +S+ NVENA+ ST+LLAQTTLR +LG
Sbjct: 136 RTVSFSVPPQEILTKDSVTTSVDAVIYYRISNATVSVANVENAHHSTRLLAQTTLRNMLG 195
Query: 575 TVDLFQLLTGRDKIAHNMQGCLDNATEIWGVKVERVDIKDVRLPIQLQXXXXXXXXXXXX 754
T L ++L+ R+ +A +MQ LD ATE WG+KVERV+IKDVRLPIQLQ
Sbjct: 196 TRSLSEILSDRETLAASMQTILDEATESWGIKVERVEIKDVRLPIQLQRAMAAEAEATRE 255
Query: 755 XXXXVIAAEGEQKASVAYKAAAIELAESPISLQLRYL 865
VIAAEGEQKAS A + AA +A+SP +LQLRYL
Sbjct: 256 ARAKVIAAEGEQKASRALRDAASVIAQSPAALQLRYL 292
>sp|Q27433|MEC2_CAEEL Mechanosensory protein 2
Length = 481
Score = 251 bits (640), Expect = 2e-66
Identities = 129/222 (58%), Positives = 160/222 (72%)
Frame = +2
Query: 200 YLFKIISLFILVVFFPISLFFCLTVVAQYERAVIFRLGRLQGKGPKGPGLVFIIPCLDSI 379
++ I+S ++ PIS C+ VV +YERAVIFRLGRL G KGPG+ FI+PC+D+
Sbjct: 119 WILTILSYLLIFFTLPISACMCIKVVQEYERAVIFRLGRLMPGGAKGPGIFFIVPCIDTY 178
Query: 380 RKIDLRTFTFNIPTQEVLTKDSVTVAVDAVVYYRIFNPVMSIVNVENANRSTKLLAQTTL 559
RK+DLR +F +P QE+L+KDSVTVAVDAVVY+RI N +S+ NVE+A RSTKLLAQTTL
Sbjct: 179 RKVDLRVLSFEVPPQEILSKDSVTVAVDAVVYFRISNATISVTNVEDAARSTKLLAQTTL 238
Query: 560 RTVLGTVDLFQLLTGRDKIAHNMQGCLDNATEIWGVKVERVDIKDVRLPIQLQXXXXXXX 739
R +LGT L ++L+ R+ I+H MQ LD ATE WGVKVERV++KDVRLP+QLQ
Sbjct: 239 RNILGTKTLAEMLSDREAISHQMQTTLDEATEPWGVKVERVEVKDVRLPVQLQRAMAAEA 298
Query: 740 XXXXXXXXXVIAAEGEQKASVAYKAAAIELAESPISLQLRYL 865
VI AEGEQKAS A K AA +AESP +LQLRYL
Sbjct: 299 EAAREARAKVIVAEGEQKASRALKEAAEVIAESPSALQLRYL 340
>sp|P27105|STOM_HUMAN Erythrocyte band 7 integral membrane protein (Stomatin) (Protein
7.2b)
Length = 288
Score = 248 bits (634), Expect = 1e-65
Identities = 120/222 (54%), Positives = 162/222 (72%)
Frame = +2
Query: 200 YLFKIISLFILVVFFPISLFFCLTVVAQYERAVIFRLGRLQGKGPKGPGLVFIIPCLDSI 379
++ S V+ FPIS++ C+ ++ +YERA+IFRLGR+ G KGPGL FI+PC DS
Sbjct: 32 WILVAFSFLFTVITFPISIWMCIKIIKEYERAIIFRLGRILQGGAKGPGLFFILPCTDSF 91
Query: 380 RKIDLRTFTFNIPTQEVLTKDSVTVAVDAVVYYRIFNPVMSIVNVENANRSTKLLAQTTL 559
K+D+RT +F+IP QE+LTKDSVT++VD VVYYR+ N +++ N+ NA+ +T+LLAQTTL
Sbjct: 92 IKVDMRTISFDIPPQEILTKDSVTISVDGVVYYRVQNATLAVANITNADSATRLLAQTTL 151
Query: 560 RTVLGTVDLFQLLTGRDKIAHNMQGCLDNATEIWGVKVERVDIKDVRLPIQLQXXXXXXX 739
R VLGT +L Q+L+ R++IAHNMQ LD+AT+ WG+KVERV+IKDV+LP+QLQ
Sbjct: 152 RNVLGTKNLSQILSDREEIAHNMQSTLDDATDAWGIKVERVEIKDVKLPVQLQRAMAAEA 211
Query: 740 XXXXXXXXXVIAAEGEQKASVAYKAAAIELAESPISLQLRYL 865
VIAAEGE AS A K A++ + ESP +LQLRYL
Sbjct: 212 EASREARAKVIAAEGEMNASRALKEASMVITESPAALQLRYL 253
>sp|P54116|STOM_MOUSE Erythrocyte band 7 integral membrane protein (Stomatin) (Protein
7.2b)
Length = 284
Score = 248 bits (632), Expect = 2e-65
Identities = 123/241 (51%), Positives = 171/241 (70%)
Frame = +2
Query: 143 VPERFAARESKFSFIQTFEYLFKIISLFILVVFFPISLFFCLTVVAQYERAVIFRLGRLQ 322
+PE F RE+ + + ++ +S +++ FPIS++ C+ +V +YER +IFRLGR+
Sbjct: 15 IPESF--RENSKTELGACGWILVAVSFIFVLITFPISIWICIKIVKEYERVIIFRLGRIL 72
Query: 323 GKGPKGPGLVFIIPCLDSIRKIDLRTFTFNIPTQEVLTKDSVTVAVDAVVYYRIFNPVMS 502
G KGPGL FI+PC DS K+D+RT +F+IP QEVLTKDSVT++VD VVYYR+ N ++
Sbjct: 73 QGGAKGPGLFFILPCTDSFIKVDMRTISFDIPPQEVLTKDSVTISVDGVVYYRVQNATLA 132
Query: 503 IVNVENANRSTKLLAQTTLRTVLGTVDLFQLLTGRDKIAHNMQGCLDNATEIWGVKVERV 682
+ N+ NA+ +T+LLAQTTLR LGT +L Q+L+ R++IAH+MQ LD+AT+ WG+KVERV
Sbjct: 133 VANITNADSATRLLAQTTLRNALGTKNLSQILSDREEIAHHMQSTLDDATDDWGIKVERV 192
Query: 683 DIKDVRLPIQLQXXXXXXXXXXXXXXXXVIAAEGEQKASVAYKAAAIELAESPISLQLRY 862
+IKDV+LP+QLQ VIAAEGE AS A K A++ + ESP +LQLRY
Sbjct: 193 EIKDVKLPVQLQRAMAAEAEAAREARAKVIAAEGEMNASRALKEASMVITESPAALQLRY 252
Query: 863 L 865
L
Sbjct: 253 L 253
>sp|Q22165|STO4_CAEEL Stomatin protein 4
Length = 281
Score = 246 bits (628), Expect = 6e-65
Identities = 127/222 (57%), Positives = 162/222 (72%)
Frame = +2
Query: 200 YLFKIISLFILVVFFPISLFFCLTVVAQYERAVIFRLGRLQGKGPKGPGLVFIIPCLDSI 379
++ IIS +++ P+S FFCL VV +YERAVIFRLGRL+ G +GPG+ FIIPC++S
Sbjct: 28 WIITIISYLVVLFTLPLSAFFCLKVVQEYERAVIFRLGRLKHGGARGPGIFFIIPCIESF 87
Query: 380 RKIDLRTFTFNIPTQEVLTKDSVTVAVDAVVYYRIFNPVMSIVNVENANRSTKLLAQTTL 559
+KIDLR +F++P QE+L+KDSVTV+VDAV+Y+RI N +S++NVE+A RSTKLLAQTTL
Sbjct: 88 KKIDLRVVSFDVPPQEILSKDSVTVSVDAVIYFRISNATVSVINVEDAARSTKLLAQTTL 147
Query: 560 RTVLGTVDLFQLLTGRDKIAHNMQGCLDNATEIWGVKVERVDIKDVRLPIQLQXXXXXXX 739
R LGT L ++L+ RD I+ MQ LD AT+ WGVKVERV+IKDVRLPIQLQ
Sbjct: 148 RNFLGTRTLAEMLSSRDAISMQMQAALDEATDPWGVKVERVEIKDVRLPIQLQRAMAAEA 207
Query: 740 XXXXXXXXXVIAAEGEQKASVAYKAAAIELAESPISLQLRYL 865
+IAAEGEQ AS A AA +A SP ++QLRYL
Sbjct: 208 EAARAAGAKIIAAEGEQLASRALADAADVIATSPCAIQLRYL 249
>sp|Q8TAV4|STML3_HUMAN Stomatin-like protein 3
Length = 291
Score = 244 bits (623), Expect = 2e-64
Identities = 117/217 (53%), Positives = 162/217 (74%)
Frame = +2
Query: 215 ISLFILVVFFPISLFFCLTVVAQYERAVIFRLGRLQGKGPKGPGLVFIIPCLDSIRKIDL 394
+S ++++ FPIS++ CL ++ +YERAV+FRLGR+Q KGPGL+ ++PC+D K+DL
Sbjct: 34 LSFLLVIITFPISIWMCLKIIKEYERAVVFRLGRIQADKAKGPGLILVLPCIDVFVKVDL 93
Query: 395 RTFTFNIPTQEVLTKDSVTVAVDAVVYYRIFNPVMSIVNVENANRSTKLLAQTTLRTVLG 574
RT T NIP QE+LT+DSVT VD VVYYRI++ V ++ NV + +++T LLAQTTLR VLG
Sbjct: 94 RTVTCNIPPQEILTRDSVTTQVDGVVYYRIYSAVSAVANVNDVHQATFLLAQTTLRNVLG 153
Query: 575 TVDLFQLLTGRDKIAHNMQGCLDNATEIWGVKVERVDIKDVRLPIQLQXXXXXXXXXXXX 754
T L Q+L GR++IAH++Q LD+ATE+WG++V RV+IKDVR+P+QLQ
Sbjct: 154 TQTLSQILAGREEIAHSIQTLLDDATELWGIRVARVEIKDVRIPVQLQRSMAAEAEATRE 213
Query: 755 XXXXVIAAEGEQKASVAYKAAAIELAESPISLQLRYL 865
V+AAEGE AS + K+A++ LAESPI+LQLRYL
Sbjct: 214 ARAKVLAAEGEMNASKSLKSASMVLAESPIALQLRYL 250
>sp|Q6PE84|STML3_MOUSE Stomatin-like protein 3 (Stomatin-related olfactory protein)
Length = 287
Score = 244 bits (623), Expect = 2e-64
Identities = 117/222 (52%), Positives = 165/222 (74%)
Frame = +2
Query: 200 YLFKIISLFILVVFFPISLFFCLTVVAQYERAVIFRLGRLQGKGPKGPGLVFIIPCLDSI 379
++ +S +++V FPIS++ CL ++ +YERAV+FRLGR+Q KGPGL+ ++PC+D
Sbjct: 25 WILFFLSFLLMLVTFPISVWMCLKIIKEYERAVVFRLGRIQADKAKGPGLILVLPCIDVF 84
Query: 380 RKIDLRTFTFNIPTQEVLTKDSVTVAVDAVVYYRIFNPVMSIVNVENANRSTKLLAQTTL 559
K+DLRT T NIP QE+LT+DSVT VD VVYYRI++ V ++ NV + +++T LLAQTTL
Sbjct: 85 VKVDLRTVTCNIPPQEILTRDSVTTQVDGVVYYRIYSAVSAVANVNDVHQATFLLAQTTL 144
Query: 560 RTVLGTVDLFQLLTGRDKIAHNMQGCLDNATEIWGVKVERVDIKDVRLPIQLQXXXXXXX 739
R VLGT L Q+L+GR++IAH++Q LD+ATE+WG++V RV+IKDVR+P+QLQ
Sbjct: 145 RNVLGTQTLSQILSGREEIAHSIQTLLDDATELWGIRVARVEIKDVRIPVQLQRSMAAEA 204
Query: 740 XXXXXXXXXVIAAEGEQKASVAYKAAAIELAESPISLQLRYL 865
V+AAEGE AS + K+A++ LAESP++LQLRYL
Sbjct: 205 EATREARAKVLAAEGEMNASKSLKSASMVLAESPVALQLRYL 246
>sp|Q21190|UNC1_CAEEL Uncoordinated protein 1 (Protein unc-1)
Length = 285
Score = 226 bits (575), Expect = 8e-59
Identities = 116/224 (51%), Positives = 155/224 (69%)
Frame = +2
Query: 194 FEYLFKIISLFILVVFFPISLFFCLTVVAQYERAVIFRLGRLQGKGPKGPGLVFIIPCLD 373
F Y + +S +++V FP S+ CL V+ +YER VIFR+GRL G +GPG++FIIPC+D
Sbjct: 31 FGYALQALSWILIIVTFPFSMCVCLKVIKEYERVVIFRIGRLVFGGARGPGMIFIIPCID 90
Query: 374 SIRKIDLRTFTFNIPTQEVLTKDSVTVAVDAVVYYRIFNPVMSIVNVENANRSTKLLAQT 553
+ RKIDLR ++ +P QE+L+KDSVTV+VDAVVY+R +P+ S+ NV++A STKLLAQT
Sbjct: 91 TYRKIDLRVVSYAVPPQEILSKDSVTVSVDAVVYFRTSDPIASVNNVDDAIYSTKLLAQT 150
Query: 554 TLRTVLGTVDLFQLLTGRDKIAHNMQGCLDNATEIWGVKVERVDIKDVRLPIQLQXXXXX 733
TLR LG L ++LT R+ IA + LD TE WGVKVERV++KD+RLP QL
Sbjct: 151 TLRNALGMKTLTEMLTEREAIAQLCETILDEGTEHWGVKVERVEVKDIRLPQQLTRAMAA 210
Query: 734 XXXXXXXXXXXVIAAEGEQKASVAYKAAAIELAESPISLQLRYL 865
V+AAEGEQKAS A K AA + +P++LQLR+L
Sbjct: 211 EAEAAREARAKVVAAEGEQKASRALKEAADVIQANPVALQLRHL 254
>sp|Q19200|STO1_CAEEL Stomatin protein 1
Length = 330
Score = 222 bits (566), Expect = 9e-58
Identities = 111/217 (51%), Positives = 159/217 (73%)
Frame = +2
Query: 215 ISLFILVVFFPISLFFCLTVVAQYERAVIFRLGRLQGKGPKGPGLVFIIPCLDSIRKIDL 394
+S ++ + FP+S+F C+ +V +Y+RAV+FRLGRL KGPG+ FIIPC+D+ IDL
Sbjct: 47 MSYVLIFLTFPVSVFMCIKIVQEYQRAVVFRLGRLV-PDVKGPGIFFIIPCIDTFLNIDL 105
Query: 395 RTFTFNIPTQEVLTKDSVTVAVDAVVYYRIFNPVMSIVNVENANRSTKLLAQTTLRTVLG 574
R ++N+P+QE+L++DSVTV+VDAVVY+++F+P+ S+V V NA STKLLAQTTLRT+LG
Sbjct: 106 RVASYNVPSQEILSRDSVTVSVDAVVYFKVFDPITSVVGVGNATDSTKLLAQTTLRTILG 165
Query: 575 TVDLFQLLTGRDKIAHNMQGCLDNATEIWGVKVERVDIKDVRLPIQLQXXXXXXXXXXXX 754
T L ++L+ R+KI+ +M+ LD ATE WG+KVERV+++DVRLP Q+Q
Sbjct: 166 THTLSEILSDREKISADMKISLDEATEPWGIKVERVELRDVRLPSQMQRAMAAEAEATRD 225
Query: 755 XXXXVIAAEGEQKASVAYKAAAIELAESPISLQLRYL 865
+IAAEGE +AS A AA +++S ++QLRYL
Sbjct: 226 AGAKIIAAEGELRASAALAEAATIISKSEGAMQLRYL 262
>sp|Q20657|STO3_CAEEL Stomatin protein 3
Length = 267
Score = 211 bits (537), Expect = 2e-54
Identities = 105/224 (46%), Positives = 155/224 (69%)
Frame = +2
Query: 194 FEYLFKIISLFILVVFFPISLFFCLTVVAQYERAVIFRLGRLQGKGPKGPGLVFIIPCLD 373
F+++ I + L++ FP+S+FFC+ +V +Y+R VIFRLGRL P+GPG+V ++P +D
Sbjct: 15 FDFVALICAWAFLLLTFPVSIFFCVKIVKEYDRMVIFRLGRLWQDNPRGPGIVLVLPFID 74
Query: 374 SIRKIDLRTFTFNIPTQEVLTKDSVTVAVDAVVYYRIFNPVMSIVNVENANRSTKLLAQT 553
S + +DLR ++++PTQE+LT+DSVT+ VDA VYYR +P+ S+ V +A+ ST+ LAQ+
Sbjct: 75 SHKTVDLRVMSYDVPTQEMLTRDSVTIGVDAAVYYRTSDPIASLARVNDAHMSTRQLAQS 134
Query: 554 TLRTVLGTVDLFQLLTGRDKIAHNMQGCLDNATEIWGVKVERVDIKDVRLPIQLQXXXXX 733
+LR VLGT L +L+T R IA ++ LD+AT WG+ VERV+IKD+RLP ++
Sbjct: 135 SLRNVLGTRSLAELMTDRHGIAVQVKYILDSATLFWGIHVERVEIKDIRLpreMCRAMAA 194
Query: 734 XXXXXXXXXXXVIAAEGEQKASVAYKAAAIELAESPISLQLRYL 865
V+ A+GE AS+A++ AA ELA SP +LQLRYL
Sbjct: 195 EAEAQRESDAKVVTAQGELDASMAFQKAADELAGSPTALQLRYL 238
Database: Non-redundant SwissProt sequences
Posted date: Dec 6, 2005 7:40 AM
Number of letters in database: 68,354,980
Number of sequences in database: 184,735
Database: swissprot.01
Posted date: Dec 6, 2005 8:18 AM
Number of letters in database: 66,202,850
Number of sequences in database: 184,431
Lambda K H
0.318 0.134 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 74,402,953
Number of Sequences: 369166
Number of extensions: 1254439
Number of successful extensions: 3271
Number of sequences better than 10.0: 10
Number of HSP's better than 10.0 without gapping: 3176
Number of HSP's successfully gapped in prelim test: 0
Number of HSP's that attempted gapping in prelim test: 0
Number of HSP's gapped (non-prelim): 3246
length of database: 68,354,980
effective HSP length: 110
effective length of database: 48,034,130
effective search space used: 8550075140
frameshift window, decay const: 40, 0.1
T: 12
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)